Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2K5VP)

Drug Name

Coxsackievirus A21 Drug Info

Synonyms

Cavatak (TN)

Indication

Disease Entry	ICD 11	Status	REF
Glioblastoma multiforme	2A00.0	Phase 2	[1]
Bladder cancer	2C94	Phase 1/2	[2]
Lung cancer	2C25.0	Phase 1/2	[2]
Melanoma	2C30	Phase 1/2	[2]
Prostate cancer	2C82.0	Phase 1/2	[2]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Complement decay-accelerating factor (CD55)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PAT-SC1	DMZKFJO	Gastric adenocarcinoma	2B72	Phase 1/2	[3]
Onyvax-105	DMGIN7J	Prostate cancer	2C82.0	Phase 1/2	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Complement decay-accelerating factor (CD55)	TT5Z9WY	DAF_HUMAN	Inhibitor	[1]

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References

1	Oncolytic Coxsackievirus A21 as a novel therapy for multiple myeloma. Br J Haematol. 2007 Apr;137(2):133-41.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1. Oncol Rep. 2014 Mar;31(3):1059-66.
4	Technology evaluation: Onyvax-105, Onyvax. Curr Opin Mol Ther. 2003 Dec;5(6):668-72.