Details of the Drug

General Information of Drug (ID: DM2K5VP)

Drug Name
Coxsackievirus A21
Synonyms Cavatak (TN)
Indication
Disease Entry ICD 11 Status REF
Glioblastoma multiforme 2A00.0 Phase 2 [1]
Bladder cancer 2C94 Phase 1/2 [2]
Lung cancer 2C25.0 Phase 1/2 [2]
Melanoma 2C30 Phase 1/2 [2]
Prostate cancer 2C82.0 Phase 1/2 [2]
Cross-matching ID
TTD ID
D0C4BL
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement decay-accelerating factor (CD55) TT5Z9WY DAF_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Glioblastoma multiforme
ICD Disease Classification 2A00.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement decay-accelerating factor (CD55) DTT CD55 2.44E-02 2.16 3.38
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Oncolytic Coxsackievirus A21 as a novel therapy for multiple myeloma. Br J Haematol. 2007 Apr;137(2):133-41.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)