General Information of Drug (ID: DM2YAUX)

Drug Name
4(Z)-(5'-Deoxyadenosin-5'-ylidene)butanoic acid Drug Info
Synonyms CHEMBL525000
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44576814
TTD Drug ID
DM2YAUX

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ARISTEROMYCIN DMRXB74 N. A. N. A. Terminated [2]
Nicotinamide-Adenine-Dinucleotide DM9LRKB N. A. N. A. Investigative [3]
2-Propanol, Isopropanol DML5O0H Discovery agent N.A. Investigative [4]
Neplanocin A DMXULGK Discovery agent N.A. Investigative [5]
5'-deoxy-5'-ureidoadenosine DM8IQX4 Discovery agent N.A. Investigative [6]
5(E)-(5'-Deoxyadenosin-5'-ylidene)pentanoic acid DM1IGOD Discovery agent N.A. Investigative [1]
5-methylenearisteromycin DMIQ1X3 Discovery agent N.A. Investigative [2]
NORARISTEROMYCIN DMZ9024 Discovery agent N.A. Investigative [7]
D-Eritadenine DM2XT7S N. A. N. A. Investigative [3]
5'-S-ethyl-5'-thioadenosine DM0PQH1 Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adenosylhomocysteinase (AHCY) TTE2KUJ SAHH_HUMAN Inhibitor [1]

References

1 Synthesis of 5'-functionalized nucleosides: S-Adenosylhomocysteine analogues with the carbon-5' and sulfur atoms replaced by a vinyl or halovinyl u... Bioorg Med Chem. 2008 May 15;16(10):5424-33.
2 Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase. Bioorg Med Chem. 2008 Apr 1;16(7):3809-15.
3 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
5 Molecular approaches for the treatment of hemorrhagic fever virus infections. Antiviral Res. 1993 Sep;22(1):45-75.
6 Design, synthesis, and molecular modeling studies of 5'-deoxy-5'-ureidoadenosine: 5'-ureido group as multiple hydrogen bonding donor in the active ... Bioorg Med Chem Lett. 2007 Aug 15;17(16):4456-9.
7 Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocystein... Bioorg Med Chem Lett. 2008 Apr 15;18(8):2615-8.