Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM79E2K)

• Drug Name: Aminodeoxykanamycin Drug Info
• Synonyms: Aminodeoxykanamycin; bekanamycin; Kanamycin B; nebramycin factor 5; Bekanamycine; Bekanamycinum; Becanamicina; Bekanamycinum [INN-Latin]; Bekanamycine [INN-French]; Becanamicina [INN-Spanish]; EINECS 225-170-5; BRN 0061646; Aminodeoxykanamycin sulfate; 4696-76-8; Antibiotic derived from Streptomyces kanamyceticus; AC1L2FQA; AC1Q57UP; Antibiotic derived from Streptomyces kanamyceticus. Kanamycin B; (1r,2s,4r,6s)-4,6-diamino-3-[(3-amino-3-deoxy-; A-d-glucopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 439318
  ChEBI ID: CHEBI:28098
  CAS Number: CAS 4696-76-8
  TTD Drug ID: DM79E2K

Molecule-Related Drug Atlas

Drug(s) Targeting Bacterial 16S ribosomal RNA (Bact 16S rRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Framycetin	DMF8DNE	Acute liver failure	DB91	Approved	[2]
Oxazolidinones	DMBM47Z	Gram-positive bacterial infection	1B74-1G40	Phase 2	[3]
Apramycin	DMU8QD2	Gram-negative bacterial infection	1B74-1G40	Phase 1	[1]
G418	DMKTJBU	Discovery agent	N.A.	Investigative	[1]
Hygromycin B	DMEZ92A	Discovery agent	N.A.	Investigative	[1]
Ribostamycin	DMXWUHA	Discovery agent	N.A.	Investigative	[1]
Neamine	DMNCU6H	Discovery agent	N.A.	Investigative	[1]
Butirosin B	DMR6GJK	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial 16S ribosomal RNA (Bact 16S rRNA)	TT38DW5	NOUNIPROTAC	Inhibitor	[1]

References

• [1] RNA as a target for small molecules. Curr Opin Chem Biol. 2000 Dec;4(6):678-86.
• [2] Antistaphylococcal activity of gentamicin. Minerva Med. 1975 Dec 8;66(84):4505-26.
• [3] Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors. RNA. 1999 Jul;5(7):939-46.