Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7N3MX)

Drug Name
3,4-dihydroxyphenylacetaldehyde Drug Info
Synonyms DOPAL
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
119219
ChEBI ID
CHEBI:27978
CAS Number
CAS 5707-55-1
TTD Drug ID
DM7N3MX
INTEDE Drug ID
DR2034

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Aminomuconic semialdehyde dehydrogenase (ALDH12) DE870HF AL8A1_HUMAN Substrate [2]
Aldehyde dehydrogenase 7 (ALDH7) DE2ZWSM AL3B1_HUMAN Substrate [2]
Aldehyde dehydrogenase 5 (ALDHX) DEXI4UQ AL1B1_HUMAN Substrate [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6632).
2 Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase. Pharmacol Rev. 2007 Jun;59(2):125-50.