Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMC013U)

Drug Name

6-Thiophen-2-yl-imidazo[2,1-b]thiazole Drug Info

Synonyms

6-(thiophen-2-yl)imidazo[2,1-b][1,3]thiazole; AC1Q7FWK; AC1N51XV; CHEMBL12113; IFLab2_000013; IFLab1_003798; MolPort-000-476-548; HMS1422M14; ZINC406855; STL115074; CCG-22586; AKOS002232733; MCULE-2716534216; 6-(2-Thienyl)imidazo[2,1-b]thiazole; IDI1_019039; IDI1_009905; imidazo[2,1-b]thiazole,6-(2-thienyl)-; KB-305118; EU-0080970; ST50113084; 6-(2-thienyl)imidazo[2,1-b]1,3-thiazoline; 6-thiophen-2-ylimidazo[2,1-b][1,3]thiazole; SR-01000506671

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 4164759
TTD Drug ID: DMC013U

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

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Drug(s) Targeting NADH dehydrogenase (MT-ND3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NADH	DM5NM6E	Parkinson disease	8A00.0	Approved	[2]
N-Formylmethionine	DM7GBDX	Discovery agent	N.A.	Investigative	[3]
6-Thiophen-3-yl-imidazo[2,1-b]thiazole	DM90VJ6	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
NADH dehydrogenase (MT-ND3)	TTTJF7V	NU3M_HUMAN	Inhibitor	[1]

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References

1	Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase. J Med Chem. 1995 Mar 31;38(7):1090-7.
2	Mechanism of cadmium-decreased glucuronidation in the rat. Biochem Pharmacol. 1992 Dec 1;44(11):2139-47.
3	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.