Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DME29PX)

Drug Name
4-Hydroxy-1,2,5-Thiadiazole-3-Carboxylic Acid Drug Info
Synonyms
4-HYDROXY-1,2,5-THIADIAZOLE-3-CARBOXYLIC ACID; LDHA Inhibitor, 1; 45654-48-6; GBD; AC1L9M6Z; C3H2N2O3S; 1,2,5-Thiadiazole, TDA1; SCHEMBL2573610; CHEMBL1232973; BDBM23251; MolPort-006-168-875; ZINC6523896; AKOS006380523; DB03162; 4-oxo-1,2,5-thiadiazole-3-carboxylic acid; Z2467454497; 4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
448652
CAS Number
CAS 45654-48-6
TTD Drug ID
DME29PX

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting L-lactate dehydrogenase (LDH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nicotinamide-Adenine-Dinucleotide DM9LRKB N. A. N. A. Investigative [1]
OXAMATE DMTYBC9 Discovery agent N.A. Investigative [1]
3,7-DIHYDROXYNAPHTHALENE-2-CARBOXYLIC ACID DMJ0654 Discovery agent N.A. Investigative [2]
4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid DM6WJ4K Discovery agent N.A. Investigative [1]
3-Hydroxyisoxazole-4-Carboxylic Acid DMKLZXV Discovery agent N.A. Investigative [1]
Naphthalene-2,6-disulfonic acid DMLHWNG Discovery agent N.A. Investigative [3]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
L-lactate dehydrogenase (LDH) TTAZHU0 LDHA_HUMAN; LDHB_HUMAN; LDHC_HUMAN Inhibitor [1]

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
3 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.