Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFGQ2S)

Drug Name
Erythrityl Tetranitrate Drug Info
Synonyms
Cardilate; Cardiloid; Cardivell; Cardiwell; Erythritetranitrat; Nitroerythrit; Nitroerythrite; Nitroerythrol; Tetranitrin; Tetranitrol; Eritritile tetranitrato; Eritritile tetranitrato [DCIT]; Eritrityl tetranitrate; Eritrityli tetranitras; Erythritol tetranitrate; Erythrityl tetranitrate [USAN]; Erythrol tetranitrate; Tetranitrato de eritritilo; Eritrityli tetranitras [INN-Latin]; Erythritol, tetranitrate; Meso-Erythritol tetranitrate; Tetranitrate d'erithrityle; Tetranitrate d'eritrityle; Tetranitrato de eritritilo [INN-Spanish]; Erythritol, tetranitrate (8CI); Tetranitrate d'eritrityle [INN-French]; 1,2,3,4-Butanetetralyl tetranitrate; 1,3,4-trinitrooxybutan-2-yl nitrate
Indication
Disease Entry ICD 11 Status REF
Angina pectoris BA40 Approved [1]
Therapeutic Class
Vasodilator Agents
Cross-matching ID
PubChem CID
5284553
ChEBI ID
CHEBI:60072
CAS Number
CAS 7297-25-8
TTD Drug ID
DMFGQ2S

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Guanylate cyclase (GC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Respiratory failure CB41 Approved [2]
Isosorbide dinitrate DMBI4JG Anal fissure DB50.0 Approved [2]
Methylene blue DMJAPE7 Acquired methemoglobinemia 3A93 Approved [4]
Isosorbide mononitrate DMYLMU0 Hydrocephalus 8D64 Approved [2]
Pirsidomine DMHI6GE Angina pectoris BA40 Phase 2 [5]
IW-1701 DM457XO Sickle-cell disorder 3A51 Phase 2 [6]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Guanylate cyclase (GC) TT6HPVC NOUNIPROTAC Stimulator [2] , [3]

References

1 Drug information of Erythrityl Tetranitrate, 2008. eduDrugs.
2 Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart. Mol Cell Biochem. 2010 Jan;333(1-2):191-201.
3 Nitric oxide modulation of the growth hormone-releasing activity of Hexarelin in young and old dogs. Metabolism. 1999 Feb;48(2):176-82.
4 Curcumin ameliorates high glucose-induced acute vascular endothelial dysfunction in rat thoracic aorta. Clin Exp Pharmacol Physiol. 2009 Dec;36(12):1177-82.
5 Activation of soluble guanylyl cyclase by the nitrovasodilator 3-morpholinosydnonimine involves formation of S-nitrosoglutathione. Mol Pharmacol. 1998 Jul;54(1):207-12.
6 Clinical pipeline report, company report or official report of Cyclerion Therapeutics.