Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHI6GE)

Drug Name
Pirsidomine Drug Info
Synonyms C87-3754; CAS-936
Indication
Disease Entry ICD 11 Status REF
Angina pectoris BA40 Phase 2 [1]
Cross-matching ID
PubChem CID
9571076
CAS Number
CAS 132722-74-8
TTD Drug ID
DMHI6GE

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Guanylate cyclase (GC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [3]
Isosorbide Dinitrate DMBI4JG Anal fissure DB50.0 Approved [3]
Methylene blue DMJAPE7 Acquired methemoglobinemia 3A93 Approved [4]
Isosorbide Mononitrate DMYLMU0 Angina pectoris BA40 Approved [3]
Erythrityl Tetranitrate DMFGQ2S Angina pectoris BA40 Approved [3]
IW-1701 DM457XO Sickle-cell disorder 3A51 Phase 2 [5]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Guanylate cyclase (GC) TT6HPVC NOUNIPROTAC Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001151)
2 Activation of soluble guanylyl cyclase by the nitrovasodilator 3-morpholinosydnonimine involves formation of S-nitrosoglutathione. Mol Pharmacol. 1998 Jul;54(1):207-12.
3 Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart. Mol Cell Biochem. 2010 Jan;333(1-2):191-201.
4 Curcumin ameliorates high glucose-induced acute vascular endothelial dysfunction in rat thoracic aorta. Clin Exp Pharmacol Physiol. 2009 Dec;36(12):1177-82.
5 Clinical pipeline report, company report or official report of Cyclerion Therapeutics.