Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJ18YL)

Drug Name
Secnidazole Drug Info
Synonyms
3366-95-8; Secnidazol; Secnidazolum; Flagentyl; Secnidazolum [INN-Latin]; Solosec; RP 14539; Secnidazol [INN-Spanish]; PM 185184;Secnidazole (Flagentyl); SYM-1219; EINECS 222-134-0; seknidazol; MLS000559043; PM-185184; NCGC00095158-01; SMR000149359; RP-14539
Indication
Disease Entry ICD 11 Status REF
Amoebiasis 1A36 Approved [1]
Bacterial vaginosis MF3A Approved [2]
Cross-matching ID
PubChem CID
71815
ChEBI ID
CHEBI:94433
CAS Number
CAS 3366-95-8
TTD Drug ID
DMJ18YL
INTEDE Drug ID
DR2431
ACDINA Drug ID
D01418

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DME
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Metabolized By Nitroreductase (NTR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metronidazole DMTIVEN Abscess Approved [3]
Tindamax DM3OWT4 Bacterial infection 1A00-1C4Z Approved [3]
AI3-23606 DMHMT49 N. A. N. A. Phase 1 [3]
BENZOQUINONE DMNBA0G Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Nitroreductase (NTR) Main DME DEAN5EW NFSB_ENTCL Substrate [3]

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85.
3 Overexpression, isotopic labeling, and spectral characterization of Enterobacter cloacae nitroreductase. Protein Expr Purif. 1998 Jun;13(1):53-60.