Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMKLZXV)

• Drug Name: 3-Hydroxyisoxazole-4-Carboxylic Acid Drug Info
• Synonyms: 3-HYDROXYISOXAZOLE-4-CARBOXYLIC ACID; 178316-78-4; GAG; AC1L9M6X; 3-isoxazolol carboxylic acid; SCHEMBL353410; CHEMBL1232960; CTK0H1143; BDBM23242; DTXSID30332285; 1,2(1,5)-Isoxazole, IOA1; AKOS022719234; AKOS006383552; 3-oxo-1,2-oxazole-4-carboxylic acid; DB02111; 3-hydroxy-1,2-oxazole-4-carboxylic acid; 3-oxo-2,3-dihydroisoxazole-4-carboxylic acid; 2429-EP2311823A1; 2429-EP2308960A1; 4-Isoxazolecarboxylicacid, 2,3-dihydro-3-oxo-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 448651
  CAS Number: CAS 178316-78-4
  TTD Drug ID: DMKLZXV

Molecule-Related Drug Atlas

Drug(s) Targeting L-lactate dehydrogenase (LDH)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Nicotinamide-Adenine-Dinucleotide	DM9LRKB	N. A.	N. A.	Investigative	[1]
OXAMATE	DMTYBC9	Discovery agent	N.A.	Investigative	[1]
3,7-DIHYDROXYNAPHTHALENE-2-CARBOXYLIC ACID	DMJ0654	Discovery agent	N.A.	Investigative	[2]
4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid	DM6WJ4K	Discovery agent	N.A.	Investigative	[1]
Naphthalene-2,6-disulfonic acid	DMLHWNG	Discovery agent	N.A.	Investigative	[3]
4-Hydroxy-1,2,5-Thiadiazole-3-Carboxylic Acid	DME29PX	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
L-lactate dehydrogenase (LDH)	TTAZHU0	LDHA_HUMAN; LDHB_HUMAN; LDHC_HUMAN	Inhibitor	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [2] DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
• [3] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.