Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRE4FC)

Drug Name

Arginine Drug Info

Synonyms

DL-Arginine hydrochloride; 32042-43-6; 2-Amino-5-guanidinopentanoic acid hydrochloride; argininhydrochlorid; DL-Arginine HCl; 220144-84-3; H-DL-Arg-OH.xHCl; DL-(+/-)-Arginine Hydrochloride; 1-Hydrochloride arginine; NSC7914; Arginine monochloride; 2-Amino-5-guanidinovaleric acid monohydrochloride; WLN: MUYZM3YZVQ & DL-Arginine hydrochloride, 98%, anhydrous; Arginine monohydrochloride, L-(+)-; ARGININE, (L); L(+)-Arginine hydrochloride; D-Arginine, hydrochloride (1:1); EINECS 250-903-0; EINECS 239-674-8

Indication

Disease Entry	ICD 11	Status	REF
Growth hormone deficiency	5A61.3	Approved	[1]

Cross-matching ID

PubChem CID: 6322
ChEBI ID: CHEBI:16467
CAS Number: CAS 74-79-3
TTD Drug ID: DMRE4FC
VARIDT Drug ID: DR00188

Molecule-Related Drug Atlas

Molecule Type:

DTP

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Transported By Mitochondrial ornithine transporter 3 (SLC25A29)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-lysine	DMOD5CK	Discovery agent	N.A.	Investigative	[4]
L-Homoarginine	DML83XP	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Mitochondrial ornithine transporter 2 (SLC25A2)	DTDPJ3F	ORNT2_HUMAN	Substrate	[2]
Sodium-coupled neutral amino acid transporter 9 (SLC38A9)	DTF7MYK	S38A9_HUMAN	Substrate	[3]
Mitochondrial ornithine transporter 3 (SLC25A29)	DT96BT4	MCATL_HUMAN	Substrate	[4]

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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Asymmetric dimethylarginine is transported by the mitochondrial carrier SLC25A2. Amino Acids. 2016 Feb;48(2):427-36.
3	Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. Science. 2015 Jan 9;347(6218):188-94.
4	The human gene SLC25A29, of solute carrier family 25, encodes a mitochondrial transporter of basic amino acids. J Biol Chem. 2014 May 9;289(19):13374-84.