Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMS10LE)

Drug Name

1-cyclohexyl-1-isopropyl-3,3-dimethylselenourea Drug Info

Synonyms

CHEMBL399930; 1-cyclohexyl-1-isopropyl-3,3-dimethylselenourea

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Bacterial Urease (Bact ureC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetohydroxamic Acid	DMYX7NI	Urinary tract infection	GC08	Approved	[2]
3-(4-bromobenzyl)-1,1-dimethylselenourea	DMAKMIJ	Discovery agent	N.A.	Investigative	[1]
3-dodecyl-1,1-dimethylthiourea	DMO5EBI	Discovery agent	N.A.	Investigative	[1]
N-glycylglycinehydroxamic acid	DMPEZHC	Discovery agent	N.A.	Investigative	[3]
3-(4-bromophenyl)-1,1-dimethylthiourea	DMXMZRE	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Facile one-pot synthesis of thio and selenourea derivatives: a new class of potent urease inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6387-91.
2	Enzymatic, immunological and phylogenetic characterization of Brucella suis urease. BMC Microbiol. 2008 Jul 19;8:121.
3	Design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases. J Med Chem. 2008 Sep 25;51(18):5736-44.