Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUDW1J)

Drug Name
3-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid Drug Info
Synonyms
3-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid; 26180-28-9; 3-(2,5-dimethylpyrrol-1-yl)benzoic acid; 3-(2,5-Dimethyl-pyrrol-1-yl)-benzoic acid; MLS000053036; Benzoic acid, m-(2,5-dimethylpyrrol-1-yl)-; SMR000068999; m-(2,5-Dimethylpyrrol-1-yl)benzoic acid; Benzoic acid,3-(2,5-dimethyl-1H-pyrrol-1-yl)-; 3-(2,5-dimethylpyrrolyl)benzoic acid; SR-01000430237; 3-(2,5-dimethylpyrrol-1-yl) benzoic acd; benzoic acid, 3-(2,5-dimethyl-1h-pyrrol-1-yl)-; BAS 00687694; AC1L4UOW; Probes2_000222; Probes2_000239; Probes1_000276
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
213329
CAS Number
CAS 26180-28-9
TTD Drug ID
DMUDW1J

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial Lethal factor (Bact lef)
Drug Name Drug ID Indication ICD 11 Highest Status REF
IQ-DAA DMHP71R Bacillus anthracis infection 1G40 Phase 1 [2]
GM6001 DM7V9CT Corneal ulcer 9A76 Discontinued in Phase 2 [3]
Bisindolylmaleimide-I DMOQJZC Discovery agent N.A. Investigative [4]
MMI270 DM38N2K Discovery agent N.A. Investigative [5]
NSC-622445 DME35CB Discovery agent N.A. Investigative [1]
N-(Sulfanylacetyl)Tyrosylprolylmethioninamide DMWJDYZ Discovery agent N.A. Investigative [3]
N-(3,4-dihydroxybenzyl)oleamide DM67XSW Discovery agent N.A. Investigative [6]
N,N'-Bis(4-Amino-2-Methylquinolin-6-Yl)Urea DMT4USP Discovery agent N.A. Investigative [3]
N-hydroxy-4-(oleamidomethyl)benzamide DMUSHZK Discovery agent N.A. Investigative [6]
N-(3,4,5-trihydroxyphenethyl)oleamide DMQ5USA Discovery agent N.A. Investigative [7]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Lethal factor (Bact lef) TTIQSC1 LEF_BACAN Inhibitor [1]

References

1 Novel small-molecule inhibitors of anthrax lethal factor identified by high-throughput screening. J Med Chem. 2006 Aug 24;49(17):5232-44.
2 Anti-toxin antibodies in prophylaxis and treatment of inhalation anthrax.Future Microbiol.2009 Feb;4(1):35-43.
3 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4 Amiodarone and bepridil inhibit anthrax toxin entry into host cells. Antimicrob Agents Chemother. 2007 Jul;51(7):2403-11.
5 The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection. Bioorg Med Chem Lett. 2006 Feb 15;16(4):964-8.
6 Inhibitors of anthrax lethal factor based upon N-oleoyldopamine. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2467-70.
7 Inhibitors of anthrax lethal factor. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4575-8.