General Information of Drug (ID: DMUOYQR)

Drug Name
AVI-5126 Drug Info
Synonyms Resten-CP; NeuGene (CABG), AVI
Indication
Disease Entry ICD 11 Status REF
Coronary artery disease BA80 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMUOYQR

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Resten-NG DMM4EJI Coronary artery disease BA80 Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Myc messenger RNA (MYC mRNA) TTNQ5ZP MYC_HUMAN Not Available [2]

References

1 ClinicalTrials.gov (NCT00451256) Safety and Efficacy Study of AVI-5126 When Used on Vein Grafts Before Use in Heart by-Pass Graft Surgery (CABG). U.S. National Institutes of Health.
2 Efficacy of a phosphorodiamidate morpholino oligomer antisense compound in the inhibition of corneal transplant rejection in a rat cornea transplant model. J Ocul Pharmacol Ther. 2012 Apr;28(2):194-201.
3 Local delivery of c-myc neutrally charged antisense oligonucleotides with transport catheter inhibits myointimal hyperplasia and positively affects vascular remodeling in the rabbit balloon injury model. Catheter Cardiovasc Interv. 2001 Oct;54(2):247-56.