Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWU17O)

Drug Name
(E,E)-1,7-Diphenyl-4,6-heptadien-3-one Drug Info
Synonyms
Alnustone; 33457-62-4; Alnusone; CHEMBL461082; 1,7-diphenylhepta-4,6-dien-3-one; 1,7-Diphenyl-4,6-heptadien-3-one; HEP-DIENE-ONE DER FR ALPINA KATSUMANDAI; AC1NSVUW; 4,6-Heptadien-3-one, 1,7-diphenyl-; (E,E)-1,7-Diphenyl-4,6-heptadien-3-one; DAH-3-keto-4,6-dien; (4E,6E)-1,7-diphenylhepta-4,6-dien-3-one; DTXSID30415724; OWMJDOUOHDOUFG-FNCQTZNRSA-N; MolPort-028-600-133; ZINC1538308; NSC378841; BDBM50300191; AKOS030524791; NSC-378841; AK544086; Y0026; trans,trans-1,7-diphenyl-1,3-heptadien-5-one
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5317598
CAS Number
CAS 33457-62-4
TTD Drug ID
DMWU17O

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Influenza Neuraminidase (Influ NA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Oseltamivir DMGO72P Influenza 1E30-1E32 Approved [2]
Zanamivir DMFMBZ4 Influenza 1E30-1E32 Approved [2]
Peramivir DMNXY5K Influenza virus infection 1E30-1E32 Approved [3]
UX-001 DMD2O0L Hereditary inclusion body myositis 4A41.2 Phase 3 [4]
CS-8958 DM4CSDH Influenza virus infection 1E30-1E32 Phase 3 [3]
DAS-181 DM0Y8JP Influenza virus infection 1E30-1E32 Phase 2 [5]
Lactose DMO4GPK Discovery agent N.A. Phase 1 [4]
GS-3435 DMV7JC6 Influenza virus infection 1E30-1E32 Terminated [6]
BCX-140 DMBJERO Influenza virus infection 1E30-1E32 Terminated [7]
Alpha-D-Mannose DMF5DLW Discovery agent N.A. Investigative [4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Influenza Neuraminidase (Influ NA) TT50QJ3 NRAM_I33A0 Inhibitor [1]

References

1 Antiviral potential and molecular insight into neuraminidase inhibiting diarylheptanoids from Alpinia katsumadai. J Med Chem. 2010 Jan 28;53(2):778-86.
2 Current and future antiviral therapy of severe seasonal and avian influenza. Antiviral Res. 2008 Apr;78(1):91-102.
3 Developing new antiviral agents for influenza treatment: what does the future hold Clin Infect Dis. 2009 Jan 1;48 Suppl 1:S3-13.
4 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
5 Inhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion protein. PLoS One. 2009 Nov 6;4(11):e7838.
6 US patent application no. 2010,0081,713, Compositions and methods for treating viral infections.
7 CN patent application no. 104447481, Benzoic acid thiourea anti-influenza virus compounds as well as preparation method and use thereof.