Details of the Drug Reposition | DrugMAP

General Information of This Drug (ID: DM58WKG)

Drug Name	Panobinostat DM58WKG
Synonyms	Faridak; LBH 589; LBH589; LBH-589; LBH-589B; NVP-LBH589; NVP-LBH-589; Panobinostat, NVP-LBH589, LBH589; (E)-N-HYDROXY-3-(4-{[2-(2-METHYL-1H-INDOL-3-YL)-ETHYLAMINO]-METHYL}-PHENYL)-ACRYLAMIDE; (E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide
Drug Type	Small molecular drug
Structure
Structure	3D MOL			2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)

4 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Primary cutaneous T-cell lymphoma	DIS35WVW	N.A.	Approved	[1]
Chronic graft versus host disease	DIS1MM9J	N.A.	Approved	[1]
Plasma cell myeloma	DIS0DFZ0	2A83.1	Approved	[1]
Non-small-cell lung cancer	DIS5Y6R9	2C25.Y	Approved	[1]
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1 Phase 3 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Type-2 diabetes	DIS3X247	5A11	Phase 3	[2]
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1 Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Primary myelofibrosis	DIS6L0CN	2A20.2	Phase 2	[2]
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References

1	Panobinostat FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7489).