Details of the Drug Reposition

General Information of This Drug (ID: DM5XPIJ)

Drug Name
Leuprolide   DM5XPIJ
Synonyms Enantone; Eligard (TN); Leuprorelin (INN); Viadur (TN); 5-oxoprolylhistidyltryptophylseryltyrosylleucylleucyl-n5-(diaminomethylidene)ornithyl-n-ethylprolinamide
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
2 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Plasma cell myeloma DIS0DFZ0 2A83.1 Approved [1]
Prostate cancer DISF190Y 2C82.0 Approved [2]
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2 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Precocious puberty DISYI2XZ N.A. Discontinued in Phase 2 [3]
High blood pressure DISY2OHH BA00 Discontinued in Phase 2 [3]
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1 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Endometriosis DISX1AG8 GA10 Investigative [1]
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References

1 Leuprolide FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1175).
3 ClinicalTrials.gov (NCT01652014) Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies