General Information of Disease (ID: DISY2OHH)

Disease Name High blood pressure
Synonyms
hypertension; HTN; high blood pressure; hyperpiesia; pressure, high blood; blood pressure, increased; hypertensive disease; vascular hypertensive disorder; increased blood pressure; blood pressure, high
Disease Class BA00: Essential hypertension
Definition
Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.
Disease Hierarchy
DISLG4XS: Arterial disorder
DISY2OHH: High blood pressure
ICD Code
ICD-11
ICD-11: BA00
ICD-10
ICD-10: I10
Expand ICD-10
I10,I11,I12,I13,I15,I20
Expand ICD-9
401413
Disease Identifiers
MONDO ID
MONDO_0005044
MESH ID
D006973
UMLS CUI
C0020538
MedGen ID
6969
HPO ID
HP:0000822
SNOMED CT ID
38341003

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 17 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Alkavervir DMB4HFI Approved NA [1]
Bendroflumethiazide DM7EVLC Approved Small molecular drug [2]
Benzthiazide DMQWZ0H Approved Small molecular drug [3]
Chlorthalidone DM4DMBT Approved Small molecular drug [4]
Ethacrynate Sodium DM5M4NT Approved Small molecular drug [1]
Ethacrynic acid DM60QMR Approved Small molecular drug [5]
Guanabenz DM5QWEL Approved Small molecular drug [6]
Irbesartan DMTP1DC Approved Small molecular drug [7]
Lisinopril DMUOK4C Approved Small molecular drug [8]
Mephentermine DMFJH5Q Approved Small molecular drug [1]
Nadolol DMW6GVL Approved Small molecular drug [9]
Nicardipine DMCDYW7 Approved Small molecular drug [10]
Olmesartan medoxomil DMWBHRY Approved Small molecular drug [11]
Pinacidil DMRADYL Approved Small molecular drug [12]
Timolol DM3NXRU Approved Small molecular drug [13]
Triamterene DM2HU9I Approved Small molecular drug [14]
Veratrum Viride Root DMJVW4H Approved NA [1]
------------------------------------------------------------------------------------
⏷ Show the Full List of 17 Drug(s)
This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Cilnidipine DM1975O Phase 3 Small molecular drug [15]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 664 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABAT TTT2LD9 Limited Biomarker [16]
ABCC8 TTP835K Limited Biomarker [17]
ABCG1 TTMWDGU Limited Biomarker [18]
ADAM17 TT6AZXG Limited Altered Expression [19]
ADORA1 TTK25J1 Limited Therapeutic [20]
AGER TTMO9HF Limited Altered Expression [21]
AHSG TTKF4WV Limited Genetic Variation [22]
AKR1B1 TTFBNVI Limited Biomarker [23]
ASIC2 TTVMWLP Limited Biomarker [24]
ASIC3 TTLGDIS Limited Biomarker [24]
ATP4A TTF1QVM Limited Biomarker [25]
AVPR2 TTK8R02 Limited ModifyingMutation [26]
B2M TTY7FKA Limited Altered Expression [27]
BCL2A1 TTGT9C7 Limited Biomarker [28]
CCNE1 TTCEJ4F Limited Biomarker [29]
CD14 TT6I7DC Limited Altered Expression [30]
CHRM2 TTYEG6Q Limited Altered Expression [31]
CLCN2 TT30NW6 Limited Biomarker [32]
COL18A1 TT63DI9 Limited Altered Expression [33]
CRLF1 TT6YF5K Limited Altered Expression [31]
CRYZ TTP6UO8 Limited Biomarker [34]
CTLA4 TTI2S1D Limited Biomarker [35]
CXCR1 TTMWT8Z Limited Biomarker [36]
CXCR2 TT30C9G Limited Biomarker [37]
CYP1A2 TTS1DTU Limited Genetic Variation [38]
DRD3 TT4C8EA Limited Biomarker [39]
DUSP1 TTG8HIM Limited Biomarker [40]
DUSP5 TTZN92A Limited Genetic Variation [41]
ENPEP TT9PBIL Limited Biomarker [42]
ESRRG TT9ZRHB Limited Biomarker [43]
F3 TT38MDJ Limited Altered Expression [44]
FCGR2B TT5RWKQ Limited Biomarker [45]
FGF23 TT2IZ4K Limited Altered Expression [46]
FGFBP1 TTV1YFT Limited Biomarker [47]
FGL2 TTYBS89 Limited Biomarker [48]
GLO1 TTV9A7R Limited Biomarker [49]
GRIA1 TTVPQTF Limited Biomarker [50]
GSTP1 TT40K12 Limited Genetic Variation [51]
HCAR1 TTVK4ZO Limited Biomarker [52]
HCRTR1 TT60Q8D Limited Biomarker [53]
HSPB8 TTY0OJN Limited Genetic Variation [54]
HSPG2 TT5UM29 Limited Biomarker [55]
IL18RAP TTZUJVE Limited Biomarker [56]
IL1R2 TT51DEV Limited Altered Expression [57]
IL31RA TT9HPX0 Limited Biomarker [58]
IL5RA TTXH9AD Limited Biomarker [59]
ITPR1 TT5HWAT Limited Biomarker [60]
ITPR3 TTH1769 Limited Biomarker [60]
KCNH1 TT9XKUC Limited Altered Expression [31]
KCNJ5 TTEO25X Limited Biomarker [61]
KCNK9 TTL4FMB Limited Biomarker [62]
KCNQ5 TTWVL5Q Limited Biomarker [63]
KDM5B TTCLI75 Limited Biomarker [64]
LSS TT7O8ZA Limited Genetic Variation [65]
LYZ TTAOZBW Limited Biomarker [66]
MAP3K10 TT9FN4J Limited Biomarker [67]
MAS1 TTOISYB Limited Altered Expression [68]
MBP TT2RY5P Limited Biomarker [69]
MC2R TTPWFDX Limited Biomarker [70]
MMP2 TTLM12X Limited Altered Expression [71]
MSLN TT4RXME Limited Biomarker [72]
MVD TTE5J6X Limited Biomarker [73]
NCF1 TTZ4JC3 Limited Biomarker [74]
NGFR TTEDJN4 Limited Biomarker [75]
OXSR1 TT7ZY03 Limited Altered Expression [76]
PABPC1 TTHC8EF Limited Biomarker [77]
PDGFB TTQA6SX Limited Biomarker [78]
PDGFC TTOABM9 Limited Biomarker [79]
PFKFB3 TTTHMQJ Limited Biomarker [80]
PKD2L1 TTAHD89 Limited Biomarker [81]
PLG TTP86E2 Limited Biomarker [82]
PPIA TTL2ADK Limited Altered Expression [83]
PRKCH TTONI0R Limited Genetic Variation [84]
PTGDR TTNVEIR Limited Altered Expression [85]
RNPEP TTD74YX Limited Biomarker [86]
SAA1 TTY0DN9 Limited Biomarker [87]
SCGB1A1 TTONPVW Limited Genetic Variation [88]
SERPINA6 TTJL8VG Limited Altered Expression [89]
SH2B3 TT36N7Z Limited Biomarker [90]
SIRT5 TTH0IOD Limited Altered Expression [91]
SLC22A2 TT0XOJN Limited Genetic Variation [92]
SLC29A4 TTTR957 Limited Altered Expression [93]
SLC36A1 TTUYIZW Limited Biomarker [94]
SLC5A7 TTRV7W3 Limited Altered Expression [31]
SORT1 TTRX9AV Limited Biomarker [95]
SRGN TTCHB06 Limited Genetic Variation [96]
ST8SIA4 TTDP8YM Limited Genetic Variation [97]
STYK1 TTRMCYJ Limited Genetic Variation [98]
TACR3 TTBPGLU Limited Biomarker [99]
TGFBR1 TTP4520 Limited Biomarker [100]
THBD TTAPV67 Limited Biomarker [101]
TICAM1 TT2GQT6 Limited Biomarker [102]
TNFSF14 TTKVENM Limited Biomarker [103]
TRPM5 TT1N8F3 Limited Biomarker [104]
UGCG TTPHEX3 Limited Biomarker [105]
XDH TT7RJY8 Limited Biomarker [106]
ADCY5 TTN64VU Disputed Biomarker [107]
ANXA1 TTUCK4B Disputed Biomarker [108]
APOB TTN1IE2 Disputed Biomarker [109]
ARSB TTESQTG Disputed Altered Expression [110]
ATG7 TTLVB9Z Disputed Biomarker [111]
ATP1A2 TT5B6HJ Disputed Biomarker [112]
BMPR2 TTGKF90 Disputed Biomarker [113]
CASP8 TT6SZNG Disputed Biomarker [114]
CASP9 TTB6T7O Disputed Biomarker [114]
CUL3 TTPCU0Q Disputed Genetic Variation [115]
CYP17A1 TTRA5BZ Disputed Biomarker [116]
EP300 TTGH73N Disputed Biomarker [117]
GGT1 TTZVT7O Disputed Genetic Variation [118]
GNAI3 TT8QF3W Disputed Therapeutic [119]
GRK3 TT5A4DX Disputed Biomarker [120]
HRH3 TT9JNIC Disputed Biomarker [121]
HSD17B4 TTL1WGS Disputed Biomarker [122]
IKBKB TTJ3E9X Disputed Biomarker [123]
ITGAV TTT1R2L Disputed Biomarker [124]
NFKBIA TTSHAEB Disputed Therapeutic [125]
OXTR TTSCIUP Disputed Biomarker [126]
PRKCD TT7A1BO Disputed Biomarker [127]
PRKCE TT57MT2 Disputed Biomarker [128]
PTK2 TTON5IT Disputed Biomarker [129]
PTPRJ TTWMKXP Disputed Biomarker [130]
RGS4 TTGTKX9 Disputed Therapeutic [131]
SQSTM1 TTOT2RY Disputed Biomarker [132]
SRC TT6PKBN Disputed Biomarker [133]
TBXAS1 TTKNWZ4 Disputed Biomarker [134]
ACAT1 TTK3C21 moderate Genetic Variation [135]
ACVR2A TTX2DRI moderate Genetic Variation [136]
ACVRL1 TTGYPTC moderate Biomarker [137]
ADAMTS1 TTS2TEI moderate Altered Expression [138]
ADAMTS4 TTYG6BU moderate Altered Expression [138]
ADM2 TTM642F moderate Biomarker [139]
AKR1C3 TT5ZWB6 moderate Biomarker [140]
ALAD TTJHKYD moderate Biomarker [141]
ALOX15 TTN9T81 moderate Biomarker [142]
ALOX5AP TTDMBF5 moderate Genetic Variation [143]
AOC3 TT7HC21 moderate Altered Expression [144]
APEX1 TTHGL48 moderate Biomarker [145]
APOA1 TT5S8DR moderate Biomarker [146]
APOH TT2OUI9 moderate Biomarker [147]
ARG1 TT7ZQEV moderate Genetic Variation [148]
ARRB2 TT8SO2I moderate Biomarker [149]
ATIC TT9NVXQ moderate Biomarker [150]
ATXN2 TTPQJ7P moderate Biomarker [151]
BGN TT0JPVF moderate Biomarker [152]
BRCA2 TTUARD6 moderate Biomarker [153]
BRD1 TTT09OB moderate Biomarker [154]
C3AR1 TTI6B3F moderate Altered Expression [155]
CACNA1D TT7RGTM moderate Genetic Variation [156]
CALR TTUZ7OA moderate Biomarker [157]
CBS TTVZJ7G moderate Posttranslational Modification [158]
CCL22 TTBTWI1 moderate Genetic Variation [159]
CCR3 TTD3XFU moderate Altered Expression [160]
COASY TT4YO0Z moderate Biomarker [161]
COL1A2 TTUABC1 moderate Altered Expression [162]
COMT TTKWFB8 moderate Biomarker [163]
CRHR2 TTIY658 moderate Biomarker [164]
CRY2 TTAO58M moderate Genetic Variation [165]
CTH TTLQUZS moderate Altered Expression [166]
CTSA TT5NILS moderate Biomarker [167]
CTSK TTDZN01 moderate Biomarker [168]
CYP2A6 TTAQ6ZW moderate Genetic Variation [169]
DAPK3 TTERVQN moderate Biomarker [170]
DLG4 TT9PB26 moderate Altered Expression [171]
F10 TTCIHJA moderate Biomarker [172]
F8 TT1290U moderate Biomarker [173]
FGF10 TTNPEFX moderate Biomarker [174]
FLT1 TT1VAUK moderate Biomarker [175]
FN1 TTPJ921 moderate Altered Expression [176]
FPR1 TT5Y4EM moderate Genetic Variation [177]
FURIN TTH9WF6 moderate Genetic Variation [156]
G6PD TTKN8W0 moderate Biomarker [178]
GAD2 TT7UY6K moderate Biomarker [179]
GCH1 TTLSWP6 moderate Biomarker [180]
GIP TT40HS5 moderate Biomarker [181]
GJB6 TTAU8SJ moderate Biomarker [182]
GLA TTIS03D moderate Genetic Variation [183]
GPR88 TTMRQY1 moderate Biomarker [184]
GPRC6A TTI1PRE moderate Biomarker [185]
GUCY1B1 TTLBYH1 moderate Biomarker [186]
HBA2 TTQO71U moderate Biomarker [187]
HDAC5 TTUELN5 moderate Biomarker [188]
HEXIM1 TTFOKAH moderate Altered Expression [189]
HMBS TTT0HW3 moderate Biomarker [190]
HTR1E TTCPG9S moderate Biomarker [191]
HTR2A TTJQOD7 moderate Biomarker [192]
HTR2B TT0K1SC moderate Altered Expression [193]
IGFBP1 TTCJTWF moderate Altered Expression [194]
IL10RB TTJTRMK moderate Biomarker [195]
IL17F TT2B6PS moderate Altered Expression [196]
IL1R1 TTWOTEA moderate Biomarker [197]
ITGB8 TTIF29E moderate Genetic Variation [198]
KCNMA1 TTE87WJ moderate Biomarker [199]
LHCGR TT2O4W9 moderate Biomarker [200]
LPA TTU9LGY moderate Genetic Variation [201]
LPAR3 TTE2YJR moderate Biomarker [185]
MBTPS1 TTNSM2I moderate Biomarker [202]
MC3R TTNI91K moderate Genetic Variation [203]
MGAM TTXWASR moderate Biomarker [204]
MMP8 TTGA1IV moderate Altered Expression [205]
MRGPRX1 TTIX6PK moderate Biomarker [185]
MSR1 TT2TDH9 moderate Genetic Variation [206]
NCR1 TTQNRJM moderate Altered Expression [207]
NOD2 TTYPUHA moderate Biomarker [208]
NOS1 TTZUFI5 moderate Biomarker [209]
NPEPPS TT371QC moderate Genetic Variation [210]
OPRK1 TTQW87Y moderate Biomarker [211]
OXER1 TT7WBSV moderate Biomarker [185]
P2RX1 TTJW7B3 moderate Altered Expression [212]
PAH TTGSVH2 moderate Altered Expression [213]
PAM TTF4ZPC moderate Genetic Variation [214]
PDGFD TTSN0GA moderate Genetic Variation [215]
PDPK1 TTYMGWX moderate Biomarker [216]
PDX1 TT8SGZK moderate Genetic Variation [217]
PLA2G7 TTDNFMT moderate Altered Expression [218]
PLCG1 TT6T4JI moderate Altered Expression [219]
PLD2 TTRLMKF moderate Biomarker [220]
PLIN1 TTIV27N moderate Genetic Variation [221]
PLOD1 TTEKJP3 moderate Genetic Variation [222]
PPARG TTT2SVW moderate Biomarker [223]
PPARGC1B TTKSQ3W moderate Altered Expression [224]
PRKACA TT5U49F moderate Biomarker [225]
PRKD1 TTSLUMT moderate Biomarker [226]
PSEN2 TTWN3F4 moderate Altered Expression [227]
PSMB8 TTEAD9J moderate Biomarker [228]
PTEN TTXJ3W7 moderate Biomarker [229]
PTGDR2 TTQDMX5 moderate Biomarker [230]
S100A12 TTQ4ESF moderate Biomarker [231]
S100A6 TT716MY moderate Biomarker [232]
SCAP TTL6U2P moderate Genetic Variation [233]
SCN10A TT90XZ8 moderate Biomarker [234]
SCN8A TT54ERL moderate Biomarker [235]
SELE TT1PL7M moderate Genetic Variation [236]
SENP1 TTW9HY5 moderate Biomarker [237]
SGCA TTS9Q5V moderate Biomarker [238]
SLC26A9 TTKRVU0 moderate Altered Expression [239]
SLC2A9 TTIF3GB moderate Genetic Variation [240]
SLC6A4 TT3ROYC moderate Biomarker [241]
SLC7A1 TT4S150 moderate Biomarker [242]
SLC8A1 TTCF82X moderate Altered Expression [243]
SLK TT8K4DE moderate Biomarker [244]
SMAD6 TTON5JB moderate Biomarker [245]
SPHK2 TTCN0M9 moderate Biomarker [202]
TACR1 TTZPO1L moderate Biomarker [246]
TAGLN TTDRZ9H moderate Biomarker [247]
TAOK3 TTO7L0V moderate Biomarker [244]
TBXA2R TT2O84V moderate Biomarker [248]
TDO2 TTXNCBV moderate Altered Expression [249]
TGFB3 TTWOMY8 moderate Altered Expression [250]
TLR3 TTD24Y0 moderate Biomarker [102]
TLR6 TTWRI8V moderate Biomarker [251]
TLR8 TT8CWFK moderate Biomarker [252]
TNFRSF11A TT3K9S2 moderate Genetic Variation [253]
TPH1 TTZSJHV moderate Biomarker [254]
TRPC3 TTNVC34 moderate Biomarker [255]
VDAC2 TTM1I7L moderate Altered Expression [256]
VDAC3 TTT48SQ moderate Biomarker [257]
VHL TTEMWSD moderate Genetic Variation [258]
VIPR2 TT4O5P0 moderate Biomarker [259]
ABCA1 TTJW1GN Strong Biomarker [260]
ABCB1 TT3OT40 Strong Genetic Variation [261]
ABCC1 TTOI92F Strong Biomarker [262]
ABCC4 TTUEAFL Strong Biomarker [263]
ABCC9 TTEF5MJ Strong Biomarker [264]
ACKR3 TTRQJTC Strong Biomarker [265]
ACR TTAHE2N Strong Altered Expression [266]
ADA TTLP57V Strong Genetic Variation [267]
ADAMTS13 TTUREBK Strong Altered Expression [268]
ADCYAP1 TTW4LYC Strong Biomarker [269]
ADCYAP1R1 TT5OREU Strong Biomarker [270]
ADGRL3 TTQST3U Strong Genetic Variation [271]
ADM TTV14YH Strong Biomarker [139]
ADORA2A TTM2AOE Strong Biomarker [272]
ADORA2B TTNE7KG Strong Biomarker [273]
ADRA1A TTNGILX Strong Biomarker [265]
ADRA1D TT34BHT Strong Biomarker [274]
ADRA2B TTWM4TY Strong Biomarker [275]
ADRA2C TT2NUT5 Strong Genetic Variation [276]
ADRB1 TTR6W5O Strong Genetic Variation [277]
ADRB3 TTMXGCW Strong Genetic Variation [278]
AGRP TT4DE1O Strong Biomarker [279]
AGTR2 TTQVOEI Strong Biomarker [280]
AGXT TTF5NVW Strong Genetic Variation [281]
AHR TT037IE Strong Biomarker [282]
AKT2 TTH24WI Strong Biomarker [283]
ALDH2 TTFLN4T Strong Genetic Variation [284]
ALOX12 TT12ABZ Strong Biomarker [285]
ALOX5 TTSJ6Q4 Strong Biomarker [286]
AMACR TTLN1AP Strong Genetic Variation [287]
AMOT TTI48OS Strong Biomarker [288]
ANGPTL3 TT59GO7 Strong Altered Expression [289]
ANO1 TTOJI4S Strong Altered Expression [290]
ANPEP TTPHMWB Strong Biomarker [291]
AOC1 TTM3B5R Strong Biomarker [292]
APCS TTB7VAT Strong Altered Expression [293]
APEH TTYWEDQ Strong Biomarker [294]
APOA4 TTNC3WS Strong Genetic Variation [295]
APOL1 TTDB8PW Strong Biomarker [296]
APP TTE4KHA Strong Biomarker [297]
AQP1 TTSF1KH Strong Biomarker [298]
AR TTKPW01 Strong Biomarker [299]
ARG2 TTV1AG6 Strong Biomarker [300]
ARRB1 TTMVD4A Strong Biomarker [301]
ASIC1 TTRJYB6 Strong Biomarker [24]
ATP1A1 TTWK8D0 Strong Genetic Variation [302]
ATP2A2 TTE6THL Strong Posttranslational Modification [303]
AVP TTJ8EWH Strong Biomarker [304]
AVPR1A TT4TFGN Strong Genetic Variation [305]
BAX TTQ57WJ Strong Altered Expression [306]
BCL2 TTFOUV4 Strong Altered Expression [307]
BDKRB1 TTG5QIA Strong Biomarker [308]
BDKRB2 TTGY8IW Strong Genetic Variation [309]
BECN1 TT5M7LN Strong Altered Expression [310]
BMP10 TTTG6H1 Strong Biomarker [137]
BMP4 TTD3BSX Strong Genetic Variation [311]
BRS3 TTKYEPM Strong Biomarker [265]
C5 TTKANGO Strong Biomarker [312]
C5AR1 TTHXFA1 Strong Altered Expression [313]
CA14 TTEYTKG Strong Genetic Variation [314]
CA2 TTANPDJ Strong Genetic Variation [315]
CACNA1C TTZIFHC Strong Biomarker [316]
CACNA1H TTZPWGN Strong Genetic Variation [317]
CACNA2D1 TTFK1JQ Strong Biomarker [318]
CALCA TTVSFJW Strong Biomarker [231]
CAPN1 TT1WBIJ Strong Altered Expression [319]
CASP3 TTPF2QI Strong Altered Expression [320]
CASR TTBUYHA Strong Biomarker [321]
CAV1 TTXUBN2 Strong Biomarker [322]
CCL2 TTNAY0P Strong Biomarker [323]
CCL21 TTLZK1U Strong Genetic Variation [324]
CCR5 TTJIH8Q Strong Biomarker [325]
CD36 TTPJMCU Strong Genetic Variation [326]
CD59 TTBGTEJ Strong Biomarker [74]
CD69 TTPQE9F Strong Biomarker [327]
CDH2 TT1WS0T Strong Biomarker [328]
CDKN2A TTFTWQ8 Strong Biomarker [329]
CETP TTFQAYR Strong Biomarker [330]
CFH TTUW6OP Strong Altered Expression [331]
CLCN3 TT8XNZ7 Strong Biomarker [332]
CLCN6 TTCJRDO Strong Genetic Variation [333]
CLCN7 TTST1AJ Strong Biomarker [334]
CLCNKA TT823N1 Strong Genetic Variation [335]
CMA1 TT8VUE0 Strong Altered Expression [336]
CMKLR1 TT4UGZL Strong Altered Expression [310]
CNP TT71P0H Strong Biomarker [337]
CNR1 TT6OEDT Strong Biomarker [338]
CPB2 TTP18AY Strong Altered Expression [339]
CPS1 TT42M75 Strong Biomarker [340]
CRH TTA7YIZ Strong Biomarker [341]
CRHR1 TT7EFHR Strong Biomarker [342]
CRY1 TT5MLZR Strong Genetic Variation [343]
CTF1 TTXGTZU Strong Genetic Variation [344]
CTSC TT4H0V2 Strong Biomarker [345]
CTSG TTQAJF1 Strong Altered Expression [346]
CX3CL1 TT1OFBQ Strong Biomarker [347]
CX3CR1 TT2T98G Strong Biomarker [348]
CXCL2 TTZF0K2 Strong Biomarker [349]
CXCR6 TT2BVUA Strong Biomarker [265]
CYP11A1 TTSYVO6 Strong Biomarker [350]
CYP1B1 TTI84H7 Strong Biomarker [351]
CYP2B6 TTMH124 Strong Altered Expression [352]
CYP2C19 TTZ58XG Strong Biomarker [353]
CYP2D6 TTVG215 Strong Genetic Variation [277]
DDR1 TTI1FPZ Strong Biomarker [354]
DHFR TTYZVDJ Strong Biomarker [355]
DIO1 TTU3X26 Strong Genetic Variation [356]
DMD TTWLFXU Strong Biomarker [357]
DPEP1 TTYUENF Strong Genetic Variation [358]
DPP4 TTDIGC1 Strong Biomarker [359]
DRD1 TTZFYLI Strong Biomarker [360]
DRD2 TTEX248 Strong Genetic Variation [361]
EBP TT4VQZX Strong Biomarker [362]
ECE1 TTQ9RYT Strong Genetic Variation [363]
EDNRA TTKRD0G Strong Biomarker [364]
EGLN1 TT9ISBX Strong Biomarker [365]
EIF2AK4 TT9U4EP Strong Genetic Variation [366]
ELANE TTPLTSQ Strong Biomarker [367]
ELK3 TT5OJMV Strong Biomarker [368]
ENPP1 TTZTIWS Strong Genetic Variation [369]
ENTPD1 TTYM8DJ Strong Biomarker [370]
EPAS1 TTWPA54 Strong Biomarker [371]
EPHA4 TTG84D3 Strong Biomarker [372]
EPHA6 TTFAHWI Strong Genetic Variation [373]
EPHB1 TT8MDAC Strong Biomarker [368]
EPHB6 TTZEMUY Strong Biomarker [374]
EPHX2 TT7WVHI Strong Biomarker [375]
EPOR TTAUX24 Strong Genetic Variation [376]
ERAP1 TT60XFL Strong Genetic Variation [377]
ESR2 TTOM3J0 Strong Biomarker [378]
F11 TTDM4ZU Strong Biomarker [379]
F11R TT3C8EG Strong Altered Expression [380]
F12 TTRJSMV Strong Biomarker [381]
F2R TTL935N Strong Biomarker [382]
F2RL3 TTD0652 Strong Biomarker [383]
F7 TTF0EGX Strong Genetic Variation [384]
FABP1 TTIV96N Strong Biomarker [385]
FABP2 TTS4YLO Strong Genetic Variation [386]
FABP3 TT3TGLR Strong Altered Expression [387]
FDXR TT3W4IX Strong Genetic Variation [388]
FES TTLBY21 Strong Genetic Variation [389]
FGF1 TTMY81X Strong Altered Expression [390]
FGF2 TTGKIED Strong Altered Expression [391]
FGF21 TTQ916P Strong Biomarker [392]
FHL1 TTI7ENL Strong Altered Expression [393]
FNDC1 TTQJCV8 Strong Genetic Variation [394]
FOS TTOM5AU Strong Biomarker [395]
FPR2 TTOJ1NF Strong Altered Expression [396]
FSHR TTZFDBT Strong Genetic Variation [397]
GAL TTXZAJ5 Strong Biomarker [398]
GCG TT6Y4PN Strong Altered Expression [399]
GCGR TT9O6WS Strong Genetic Variation [400]
GCK TTDLNGZ Strong Genetic Variation [401]
GDF15 TT4MXVG Strong Biomarker [387]
GDF2 TTAP4T1 Strong Biomarker [137]
GEM TTAZF9M Strong Biomarker [402]
GH1 TTT3YKH Strong Biomarker [403]
GHSR TTWDC17 Strong Biomarker [404]
GJA1 TT4F7SL Strong Biomarker [405]
GJA5 TTFQKZ7 Strong Biomarker [406]
GJC1 TTEP7OC Strong Therapeutic [407]
GLP1R TTVIMDE Strong Biomarker [408]
GNRH1 TT0ID4A Strong Biomarker [409]
GP1BA TTVB0Q9 Strong Biomarker [349]
GPER1 TTDSB34 Strong Biomarker [410]
GPR182 TTT23CG Strong Biomarker [411]
GPR20 TT26C7Z Strong Genetic Variation [412]
GPR35 TT254XD Strong Biomarker [413]
GPR39 TTTPCNU Strong Genetic Variation [414]
GPX1 TTYAHBP Strong Genetic Variation [415]
GRK2 TTAZ3MN Strong Biomarker [416]
GRK5 TTTCXO0 Strong Biomarker [120]
GSK3B TTRSMW9 Strong Altered Expression [417]
GSR TTEP6RV Strong Altered Expression [418]
GSTA1 TT4P8DE Strong Genetic Variation [419]
GSTO1 TTWO3SH Strong Genetic Variation [420]
HCRT TTU5HJP Strong Biomarker [421]
HDAC6 TT5ZKDI Strong Biomarker [422]
HDAC8 TTT6LFV Strong Biomarker [423]
HMGB1 TTWQYB7 Strong Biomarker [424]
HMGCS2 TTS0EZJ Strong Genetic Variation [425]
HNF1A TT01M3K Strong Genetic Variation [426]
HOXA11 TTEX4ZA Strong Genetic Variation [156]
HP TTLC8E1 Strong Biomarker [427]
HSD11B1 TTN7BL9 Strong Biomarker [428]
HSPD1 TT9HL5R Strong Biomarker [429]
HTR1B TTK8CXU Strong Altered Expression [430]
IAPP TTHN8EM Strong Biomarker [431]
ICAM1 TTA1L39 Strong Biomarker [432]
ID1 TTBXVDE Strong Altered Expression [433]
IDE TT2EDHU Strong Altered Expression [434]
IGF1R TTQFBMY Strong Biomarker [435]
IGFBP2 TTU4QSN Strong Biomarker [436]
IL16 TTW4R0B Strong Biomarker [437]
INS TTZOPHG Strong Biomarker [438]
INSR TTCBFJO Strong Altered Expression [439]
IRAK1 TTXAJWN Strong Biomarker [440]
IRS1 TTAJSQ0 Strong Biomarker [441]
ITGA2 TTSJ542 Strong Biomarker [442]
JAK2 TTRMX3V Strong Biomarker [91]
JUN TTS7IR5 Strong Biomarker [395]
KCNA5 TTW0CMT Strong Biomarker [443]
KCNJ1 TTJ13ST Strong Genetic Variation [444]
KCNJ11 TT329V4 Strong Genetic Variation [445]
KCNN3 TT9JH25 Strong Biomarker [446]
KCNQ1 TT846HF Strong Genetic Variation [447]
KLK1 TT5T3P6 Strong Biomarker [140]
KLK4 TT4319X Strong Biomarker [448]
KLKB1 TTN0PCX Strong Altered Expression [449]
KNG1 TTDJ4MY Strong Biomarker [450]
LAMC2 TTNS7H3 Strong Biomarker [451]
LEPR TT0HD6V Strong Genetic Variation [452]
LGALS3 TTFPQV7 Strong Altered Expression [453]
LIPA TTS8T1M Strong Biomarker [454]
LIPG TTHSZXO Strong Altered Expression [455]
LPAR2 TTB7Y8I Strong Biomarker [265]
LRP1 TTF2V7I Strong Genetic Variation [456]
LRP2 TTPH1AJ Strong Genetic Variation [457]
LRP5 TT7VMG4 Strong Genetic Variation [458]
LTF TTSZDQU Strong Therapeutic [459]
LYN TT1RWNJ Strong Genetic Variation [412]
MAOB TTGP7BY Strong Genetic Variation [460]
MAPK8 TT0K6EO Strong Biomarker [461]
MAPK9 TT3IVG2 Strong Biomarker [462]
MBL2 TTMQDZ5 Strong Genetic Variation [463]
MDK TTV8UE7 Strong Biomarker [464]
MIF TT6804T Strong Biomarker [465]
MLYCD TT9Z4YD Strong Biomarker [466]
MMP10 TTXLEG7 Strong Biomarker [467]
MMP3 TTUZ2L5 Strong Genetic Variation [468]
MMP7 TTMTWOS Strong Genetic Variation [469]
MMP9 TT6X50U Strong Altered Expression [470]
MTOR TTCJG29 Strong Biomarker [471]
MYD88 TTB6Q2O Strong Biomarker [472]
MYH7 TTNIMDP Strong Biomarker [473]
MYLK TT18ETS Strong Biomarker [474]
NAMPT TTD1WIG Strong Altered Expression [475]
NEDD9 TT1UREA Strong Biomarker [476]
NES TTHZ752 Strong Altered Expression [477]
NFE2L2 TTA6ZN2 Strong Genetic Variation [478]
NISCH TT789FN Strong Altered Expression [479]
NLRP3 TT4EN8X Strong Biomarker [321]
NNT TTKIH76 Strong Biomarker [480]
NOS2 TTF10I9 Strong Altered Expression [481]
NOX4 TTQRBSJ Strong Biomarker [482]
NPPC TTRK0B9 Strong Genetic Variation [483]
NPR3 TTWVLS6 Strong Biomarker [337]
NPY TT64REZ Strong Biomarker [484]
NPY1R TTRK9JT Strong Genetic Variation [485]
NPY2R TTJ6WK9 Strong Genetic Variation [486]
NQO1 TT8XK6L Strong Biomarker [487]
NR1H3 TTECBXN Strong Biomarker [488]
NR3C2 TT26PHO Strong Biomarker [489]
NR4A3 TTJQB49 Strong Genetic Variation [490]
NRG1 TTEH395 Strong Biomarker [491]
NT5E TTK0O6Y Strong Altered Expression [370]
OLR1 TTKSND3 Strong Biomarker [492]
OPA1 TTTU49Q Strong Biomarker [493]
ORAI1 TTE76YK Strong Biomarker [494]
OTC TT5KIO9 Strong Genetic Variation [495]
P2RX3 TT2THBD Strong Biomarker [496]
P2RX4 TT1NLOA Strong Genetic Variation [497]
P2RX7 TT473XN Strong Biomarker [498]
P2RY12 TTZ1DT0 Strong Genetic Variation [499]
P2RY6 TTNVSKA Strong Biomarker [500]
PADI4 TTQHAXM Strong Biomarker [501]
PCSK1 TTED9LZ Strong Genetic Variation [502]
PCSK6 TT75LN9 Strong Biomarker [337]
PDE2A TTJGW1Z Strong Biomarker [503]
PDE3B TTN34SQ Strong Genetic Variation [504]
PDE4D TTSKMI8 Strong Genetic Variation [505]
PDE5A TTJ0IQB Strong Biomarker [506]
PDGFRA TT8FYO9 Strong Altered Expression [507]
PDGFRB TTI7421 Strong Altered Expression [508]
PDK1 TTCZOF2 Strong Biomarker [216]
PECAM1 TT4EZB2 Strong Biomarker [509]
PGF TT48I1Y Strong Genetic Variation [510]
PLAT TTXAGYU Strong Biomarker [511]
POSTN TT8ALTZ Strong Biomarker [512]
PPARA TTJ584C Strong Biomarker [513]
PPARD TT2JWF6 Strong Genetic Variation [514]
PPIB TT6ZFQ4 Strong Altered Expression [515]
PRCP TTTJZ4M Strong Biomarker [516]
PRKCA TTFJ8Q1 Strong Biomarker [517]
PRKCB TTYPXQF Strong Biomarker [518]
PRKG1 TT7IZSA Strong Biomarker [519]
PROC TTZUXYS Strong Biomarker [349]
PRSS8 TTT4N0Q Strong Genetic Variation [520]
PSEN1 TTZ3S8C Strong Biomarker [153]
PTGER1 TTG1QMU Strong Genetic Variation [521]
PTGER4 TT79WV3 Strong Biomarker [522]
PTGES TTYLQ8V Strong Biomarker [523]
PTGES2 TTWU04I Strong Biomarker [524]
PTGIS TTLXKZR Strong Biomarker [525]
PTGS1 TT8NGED Strong Biomarker [526]
PTH TT6F7GZ Strong Altered Expression [527]
PTK2B TTTEFBV Strong Posttranslational Modification [528]
PTPN1 TTELIN2 Strong Therapeutic [529]
PYY TTVFJLX Strong Biomarker [486]
QPCT TTJ7YTV Strong Genetic Variation [530]
RAC1 TT2M9CG Strong Biomarker [531]
RAD51 TTC0G1L Strong Biomarker [532]
RALBP1 TTVSRUA Strong Biomarker [533]
RASA1 TTPNZ1F Strong Altered Expression [534]
RBP4 TT0C8BY Strong Biomarker [535]
RENBP TTZCG0Q Strong Biomarker [536]
RHO TTH0KSX Strong Biomarker [537]
RHOA TTP2U16 Strong Altered Expression [538]
ROBO4 TT3S9TY Strong Altered Expression [539]
ROCK1 TTZN7RP Strong Biomarker [540]
ROCK2 TTGWKQJ Strong Genetic Variation [540]
RPS6KB1 TTG0U4H Strong Biomarker [541]
RYR1 TTU5CIX Strong Biomarker [542]
S1PR1 TT9JZCK Strong Biomarker [543]
SCT TTOBVIN Strong Biomarker [544]
SELPLG TTS5K8U Strong Biomarker [545]
SERPINC1 TT4QPUL Strong Biomarker [546]
SETD2 TTPC3H4 Strong Biomarker [547]
SGK1 TTTV8EJ Strong Altered Expression [548]
SIK1 TT1H6LC Strong Altered Expression [234]
SIRT2 TTLKF5M Strong Biomarker [549]
SIRT6 TTUXYWF Strong Genetic Variation [550]
SLC12A1 TTS087L Strong Altered Expression [551]
SLC12A3 TTP362L Strong Biomarker [552]
SLC12A6 TT8DFHE Strong Biomarker [553]
SLC17A5 TTFSUIA Strong Biomarker [554]
SLC19A1 TT09I7D Strong Genetic Variation [555]
SLC22A12 TTA592U Strong Genetic Variation [556]
SLC26A4 TT7X02I Strong Biomarker [557]
SLC28A2 TTVP9IQ Strong Altered Expression [558]
SLC29A1 TTLXAKE Strong Altered Expression [93]
SLC2A1 TT79TKF Strong Biomarker [559]
SLC2A12 TTZO36H Strong Altered Expression [560]
SLC2A4 TTP6MT5 Strong Genetic Variation [561]
SLC3A2 TT5CZSM Strong Altered Expression [562]
SLC5A1 TT2UE56 Strong Biomarker [563]
SLC5A4 TTN7Y4P Strong Altered Expression [551]
SLC6A3 TTVBI8W Strong Genetic Variation [564]
SLC6A9 TTHJTF7 Strong Biomarker [565]
SLC9A1 TTGSEFH Strong Biomarker [566]
SLC9A3 TTFZVPO Strong Biomarker [567]
SLCO1B1 TTFGXEB Strong Genetic Variation [568]
SLCO1C1 TT340CE Strong Genetic Variation [356]
SLCO4C1 TTACFNR Strong Biomarker [569]
SMAD3 TTHQZV7 Strong Biomarker [570]
SMAD9 TTX8EBV Strong Biomarker [571]
SOD2 TT9O4C5 Strong Altered Expression [572]
SORD TTLSRBZ Strong Biomarker [573]
SPHK1 TTOHFIY Strong Biomarker [574]
SRR TTZFUY6 Strong Genetic Variation [575]
SST TTWF7UG Strong Genetic Variation [576]
SSTR4 TTAE1BR Strong Biomarker [265]
STS TTHM0R1 Strong Genetic Variation [577]
SUCNR1 TT4FX9Y Strong Altered Expression [578]
SULF2 TTLQTHB Strong Altered Expression [579]
TGFB1 TTR9XHZ Strong Biomarker [580]
TGFBR2 TTZE3P7 Strong Altered Expression [581]
TGM2 TT2F4OL Strong Biomarker [582]
THBS1 TTKI0H1 Strong Biomarker [583]
TLR1 TTW14D0 Strong Genetic Variation [584]
TMSB4X TTMVAIU Strong Biomarker [585]
TNC TTUCPMY Strong Biomarker [547]
TNF TTF8CQI Strong Altered Expression [586]
TNFRSF11B TT2CJ75 Strong Biomarker [587]
TNFRSF1B TT63WSF Strong Altered Expression [588]
TNNI3 TTNLDK6 Strong Biomarker [589]
TPT1 TT3PTB6 Strong Biomarker [590]
TRH TT2Z39D Strong Biomarker [591]
TRHR TT4J8MF Strong Biomarker [592]
TRIP10 TTKHTGE Strong Biomarker [593]
TRPA1 TTELV3W Strong Biomarker [594]
TRPC5 TT32NQ1 Strong Biomarker [595]
TRPC6 TTRBT3W Strong Altered Expression [596]
TRPM2 TTEBMN7 Strong Biomarker [597]
TRPM6 TTV76RD Strong Biomarker [598]
TRPM7 TTFPVZO Strong Biomarker [599]
TRPM8 TTXDKTO Strong Altered Expression [600]
TRPV1 TTMI6F5 Strong Biomarker [601]
TRPV4 TTKP2SU Strong Biomarker [602]
TSHR TT6NYJA Strong Genetic Variation [603]
TXN TTZJ5U9 Strong Biomarker [604]
TXNRD3 TTDYFVB Strong Biomarker [605]
UCP1 TTI12YJ Strong Genetic Variation [606]
UCP2 TTSC2YM Strong Altered Expression [607]
UCP3 TT12RJK Strong Biomarker [608]
ULK3 TTYENHQ Strong Biomarker [609]
USP2 TTUEQ1W Strong Genetic Variation [610]
USP8 TT1J07C Strong Genetic Variation [156]
UTRN TTNO1VA Strong Biomarker [611]
UTS2 TTERU0T Strong Biomarker [612]
UTS2R TTW5UDX Strong Altered Expression [613]
VCAM1 TTHCEF6 Strong Biomarker [614]
VDAC1 TTAMKGB Strong Biomarker [615]
VDR TTK59TV Strong Genetic Variation [616]
VEGFC TT0QUFV Strong Biomarker [617]
VIP TTGTWLF Strong Biomarker [618]
VKORC1 TTEUC8H Strong Genetic Variation [619]
WNK3 TTI7FDX Strong Biomarker [620]
WT1 TTZ8UT4 Strong Genetic Variation [621]
YES1 TT0SQ8J Strong Genetic Variation [156]
FOSL2 TT689IR Definitive Altered Expression [622]
LGR4 TTY6C71 Definitive Altered Expression [623]
PRTN3 TT5MLC4 Definitive Biomarker [624]
ROS1 TTSZ6Y3 Definitive Biomarker [625]
SLC30A8 TTXIGT7 Definitive Biomarker [626]
TRPM4 TTJ2HKA Definitive Biomarker [17]
------------------------------------------------------------------------------------
⏷ Show the Full List of 664 DTT(s)
This Disease Is Related to 35 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ATP12A DT5NLZA Limited Biomarker [25]
SLC29A2 DTW78DQ Limited Altered Expression [93]
SLC29A3 DTZAWTH Limited Altered Expression [93]
SLC2A3 DT9SQ3L Limited Biomarker [627]
SLC22A4 DT2EG60 moderate Biomarker [628]
SLC22A5 DT3HUVD moderate Biomarker [628]
SLC24A2 DTKRWE8 moderate Genetic Variation [629]
SLC28A3 DT4YL5R moderate Genetic Variation [630]
SLC2A6 DTS4MKQ moderate Genetic Variation [240]
SLC35A1 DTVZIRG moderate Biomarker [631]
SLC48A1 DTZFHNT moderate Biomarker [632]
SLC52A1 DT7NOKR moderate Biomarker [633]
ABCA3 DT2T6VQ Strong Genetic Variation [634]
ABCB6 DTF9Y2V Strong Biomarker [635]
ABCC6 DT582KR Strong Biomarker [636]
ATP7A DT0LT17 Strong Biomarker [637]
CACNB2 DTBZWL4 Strong Biomarker [638]
SLC12A2 DTHKL3Q Strong Biomarker [639]
SLC22A7 DT0OC1Q Strong Genetic Variation [156]
SLC25A20 DTQOUM4 Strong Genetic Variation [315]
SLC25A3 DTCRIWV Strong Biomarker [640]
SLC26A6 DTVGOLN Strong Genetic Variation [641]
SLC2A2 DTUJPOL Strong Altered Expression [224]
SLC2A5 DTOR02F Strong Biomarker [642]
SLC31A1 DTP8L4F Strong Biomarker [637]
SLC35F3 DTEHSG0 Strong Genetic Variation [643]
SLC39A12 DT1UIT5 Strong Biomarker [626]
SLC39A8 DTLPQGT Strong Genetic Variation [389]
SLC4A1 DTB0Q3P Strong Genetic Variation [644]
SLC4A4 DTWDEIL Strong Biomarker [645]
SLC4A7 DT03V27 Strong Genetic Variation [646]
SLC6A19 DTOTAUP Strong Genetic Variation [647]
SLC9B2 DT4JZLA Strong Biomarker [648]
SLC9C1 DT9J8DO Strong Genetic Variation [649]
SLC30A10 DTYBI73 Definitive Biomarker [626]
------------------------------------------------------------------------------------
⏷ Show the Full List of 35 DTP(s)
This Disease Is Related to 48 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
AOC2 DE8DP90 Limited Biomarker [650]
CYP2R1 DEBIHM3 Limited Biomarker [651]
CYP7A1 DEDZRQ1 Limited Genetic Variation [652]
NDUFS7 DEIW03B Limited Genetic Variation [653]
SULT1A3 DEP7E8X Limited Biomarker [654]
HSD3B2 DEN0GVQ Disputed Biomarker [655]
AKR1C4 DEAJN47 moderate Biomarker [656]
CYP2C18 DEZMWRE moderate Genetic Variation [657]
CYP4B1 DEMF740 moderate Biomarker [658]
GCLC DESYL1F moderate Biomarker [105]
GNPDA2 DEPJGQB moderate Genetic Variation [659]
MT1A DE5ME8A moderate Genetic Variation [478]
PCYT1A DEQYXD4 moderate Biomarker [660]
PER1 DE9HF0I moderate Biomarker [661]
PGPEP1 DEVDR46 moderate Genetic Variation [156]
PMM2 DEBRX3L moderate Biomarker [662]
PON2 DEHJU7E moderate Biomarker [663]
PSAT1 DEBS17P moderate Genetic Variation [210]
SI DE5EO4Y moderate Biomarker [204]
ABO DESIA7R Strong Biomarker [664]
ACSS2 DEE76VW Strong Genetic Variation [665]
ADH1B DEEN9RD Strong Genetic Variation [666]
APRT DE2MV1R Strong Biomarker [667]
BAAT DERA3OF Strong Biomarker [668]
CHDH DEAHED0 Strong Biomarker [669]
CHST3 DEQIZP2 Strong Biomarker [283]
CRMP1 DE0EUXB Strong Biomarker [611]
CYB5R3 DE4A3BL Strong Biomarker [670]
CYP4A11 DE2XQGW Strong Genetic Variation [671]
CYP4F12 DED26GV Strong Genetic Variation [98]
CYP4F3 DEFCMPI Strong Biomarker [672]
DDAH1 DEY0TQC Strong Altered Expression [673]
FAAH DEUM1EX Strong Biomarker [674]
FMO3 DEP76YL Strong Genetic Variation [675]
FXYD2 DEULQ45 Strong Biomarker [108]
GSTO2 DEHMPZR Strong Genetic Variation [420]
MAT1A DEQ6NC9 Strong Genetic Variation [676]
MAT2B DEKF1OH Strong Biomarker [605]
MTRR DE6NIY9 Strong Genetic Variation [677]
NDUFS3 DE741FI Strong Genetic Variation [678]
NT5C2 DE1DOKJ Strong Biomarker [679]
P4HA2 DE5EGK0 Strong Genetic Variation [680]
PNPO DE3Z1RA Strong Biomarker [681]
PTGDS DER3H9C Strong Altered Expression [85]
SULT1E1 DESTKG6 Strong Biomarker [682]
ACP3 DEDW5H6 Definitive Biomarker [683]
CYP3A7 DERD86B Definitive Biomarker [684]
NAT8 DEA742Z Definitive Genetic Variation [685]
------------------------------------------------------------------------------------
⏷ Show the Full List of 48 DME(s)
This Disease Is Related to 731 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACD OTC54EPO Limited Genetic Variation [686]
ADD3 OTDRSHAZ Limited Biomarker [687]
AHCYL1 OTX8L3M5 Limited Biomarker [688]
ANGPT4 OT881M3K Limited Biomarker [42]
ANGPTL1 OTXIN6V5 Limited Biomarker [42]
ANGPTL6 OTOQ5W67 Limited Biomarker [689]
APPBP2 OTLNFV4J Limited Biomarker [94]
ARMC5 OTO7IV74 Limited Biomarker [690]
ASIC5 OT1KWTC1 Limited Genetic Variation [691]
ATF2 OTNIZPEA Limited Biomarker [692]
ATP2A3 OTFYDEES Limited Biomarker [693]
BEND3 OTXPIPVP Limited Biomarker [694]
BOLA3 OTDEDY0S Limited Biomarker [695]
BUB1B OT8KME51 Limited Biomarker [696]
C4BPA OTHNH6Y8 Limited Biomarker [635]
CAMK2A OTJGX19T Limited Biomarker [697]
CAPN5 OTQ8QM7K Limited Genetic Variation [698]
CARD14 OTADQHOV Limited Biomarker [635]
CCL7 OTDIS99H Limited Biomarker [699]
CD82 OTH8MC64 Limited Biomarker [700]
CDO1 OTLG1P77 Limited Biomarker [701]
CNN2 OTH3CSXA Limited Biomarker [702]
COX4I1 OTU0FC24 Limited Biomarker [703]
COX5A OTP0961M Limited Biomarker [85]
CROT OTWK68MM Limited Biomarker [704]
DBI OT884QY9 Limited Biomarker [705]
EIF4G2 OTEO98CR Limited Biomarker [706]
FANCD2 OTVEB5LF Limited Biomarker [153]
FLCN OTVM78XM Limited Genetic Variation [707]
FMR1 OTWEV0T5 Limited Genetic Variation [708]
FOXF1 OT2CJZ5K Limited Genetic Variation [686]
GGTLC1 OTWJKUHQ Limited Biomarker [709]
GNAS OTMH8BKJ Limited Genetic Variation [710]
GOLM1 OTOZSV6O Limited Biomarker [711]
GOSR2 OTYHIYN2 Limited Biomarker [712]
GRHL3 OT1V4ZEH Limited Genetic Variation [618]
HFE OTDD93KB Limited Genetic Variation [713]
HGS OTCYYCAC Limited Genetic Variation [714]
HJV OT4235J2 Limited Genetic Variation [715]
HNRNPF OTSMBXMF Limited Biomarker [716]
HSPA14 OTZCA5LK Limited Biomarker [429]
HYLS1 OT3SW5UC Limited Biomarker [717]
IMPA1 OTBUVW1Z Limited Biomarker [718]
INPPL1 OTCDAVBQ Limited Altered Expression [719]
KCNAB1 OT25GJE9 Limited Biomarker [720]
KCNIP3 OTCQPEM4 Limited Biomarker [721]
MFSD1 OTPRRXCX Limited Biomarker [722]
MPST OTCDPH5D Limited Biomarker [67]
MRPL4 OT8AE74Y Limited Biomarker [704]
MSTO1 OT37XCNP Limited Biomarker [67]
MTPN OT5N60RU Limited Biomarker [723]
MYOC OT6DAHNF Limited Genetic Variation [724]
NDUFS4 OTJKUYEE Limited Biomarker [653]
NPHS2 OTLCNUII Limited Altered Expression [725]
NUCB2 OTHO6JWN Limited Biomarker [726]
ORAI3 OTUP3OH3 Limited Biomarker [727]
OXR1 OTPIDMT3 Limited Altered Expression [728]
PCSK1N OT7ZRW2F Limited Biomarker [729]
PDIA5 OT76ZSX5 Limited Genetic Variation [98]
PGP OT6QQ7OR Limited Biomarker [730]
PHACTR1 OTAMPX9V Limited Genetic Variation [731]
PHLDA2 OTMV9DPP Limited Biomarker [732]
PKHD1 OTAH8SMF Limited Genetic Variation [733]
PLA2G5 OTQRSKCZ Limited Genetic Variation [734]
PLCB3 OT0OMDEM Limited Biomarker [735]
PPP6C OTR1STMJ Limited Biomarker [736]
PPP6R3 OTIXD60Q Limited Biomarker [737]
PUM3 OTN1IPNS Limited Biomarker [729]
RBM4 OT5SFQA3 Limited Biomarker [738]
RGN OTD04KB1 Limited Biomarker [739]
RMDN1 OTE1NB6U Limited Biomarker [703]
RMDN2 OTK5WSFI Limited Biomarker [703]
RMDN3 OTKO7AUM Limited Biomarker [703]
RRAD OTW2O4GD Limited Genetic Variation [740]
SAA2 OTYAVJWG Limited Biomarker [87]
SAGE1 OT4H6FFA Limited Biomarker [741]
SCNN1A OTE2KVZV Limited Genetic Variation [742]
SERPINE2 OTYF5340 Limited Biomarker [743]
SORL1 OTQ8FFNS Limited Biomarker [744]
SPATA6 OTWQQONT Limited Altered Expression [307]
SSH1 OT4BE2M4 Limited Biomarker [745]
SULT1A4 OTHJ8WWV Limited Biomarker [654]
SV2C OTIH108W Limited Biomarker [746]
SYBU OT3FQV7N Limited Biomarker [703]
TCN2 OT41D0L3 Limited Genetic Variation [747]
TDRD9 OTS4UBI8 Limited Biomarker [717]
TGFBR3 OTQOOUC4 Limited Altered Expression [748]
TRIM69 OTTEGTRD Limited Biomarker [102]
TSHZ1 OTYQ9ECW Limited Biomarker [749]
TSPAN33 OTH6C0WU Limited Biomarker [729]
ACTC1 OTJU04B1 Disputed Biomarker [750]
AQP4 OTA9MYD5 Disputed Biomarker [751]
ARHGDIA OTEXWJDO Disputed Biomarker [752]
ATP5F1A OT3FZDLX Disputed Biomarker [493]
BAD OT63ERYM Disputed Therapeutic [753]
CLDN16 OTTHAIKR Disputed Biomarker [754]
CORIN OT4SK7DK Disputed Genetic Variation [755]
COX5B OTDP94F3 Disputed Biomarker [756]
CYP4A22 OTHO7KC4 Disputed Biomarker [757]
DYNLL1 OTR69LHT Disputed Therapeutic [758]
ENO1 OTB1KWJS Disputed Biomarker [759]
ENTPD2 OTZ2PKPM Disputed Biomarker [760]
FADD OTV7GFHH Disputed Therapeutic [761]
FAH OTGZA1YR Disputed Biomarker [762]
GABBR1 OTU5A52J Disputed Biomarker [763]
KCNJ8 OTZ8G8FE Disputed Biomarker [764]
KLHL3 OTEJ6850 Disputed Genetic Variation [765]
MAP1LC3A OTPMGIU4 Disputed Biomarker [132]
MSX2 OT1WDKE1 Disputed Biomarker [766]
MYH9 OT94Z706 Disputed Genetic Variation [767]
MYOD1 OTV2S79X Disputed Biomarker [768]
NR2F2 OTJFS67N Disputed Biomarker [769]
NUDT1 OTZSES3W Disputed Biomarker [770]
OXT OT48M72Z Disputed Biomarker [771]
PDCD11 OTS1NJK2 Disputed Genetic Variation [772]
PIK3R1 OT5BZ1J9 Disputed Biomarker [773]
QDPR OTSKOIUX Disputed Biomarker [774]
RFFL OT85MGDH Disputed Biomarker [775]
SCNN1G OTSJYQVQ Disputed Biomarker [776]
TJP2 OTQUY6BV Disputed Biomarker [777]
ACO1 OT2VUR7L moderate Biomarker [778]
ACSM3 OT0AE1IV moderate Biomarker [779]
ACTN4 OTCNZAJ5 moderate Biomarker [780]
ADAM11 OTPTVW5W moderate Genetic Variation [159]
ADGRA2 OTBT4W36 moderate Biomarker [184]
ADIPOR2 OT2HDTL8 moderate Biomarker [781]
ALKBH1 OTADGU5D moderate Biomarker [782]
ALMS1 OTW66JKS moderate Altered Expression [783]
AMBP OTLU8GU8 moderate Genetic Variation [784]
ANGPTL8 OTQFINCD moderate Altered Expression [289]
APBB3 OTNUTR0N moderate Genetic Variation [206]
AQP5 OT77GBY8 moderate Biomarker [785]
ARHGAP1 OT0H2ZBZ moderate Biomarker [786]
ARHGEF10 OTHJ1Y4I moderate Genetic Variation [787]
ART1 OT7FBG5W moderate Biomarker [788]
ATL1 OTR2788Y moderate Altered Expression [176]
ATOH7 OTUBW5PV moderate Biomarker [789]
ATP5PF OTDAE8FP moderate Biomarker [790]
ATP6V0A2 OTJBDX0Y moderate Biomarker [791]
BET1 OTGX2557 moderate Biomarker [792]
C1QTNF6 OT57EPQC moderate Altered Expression [793]
CACUL1 OT6P1ZVP moderate Genetic Variation [794]
CAMK4 OT47RDGV moderate Genetic Variation [795]
CARTPT OTTE4V9S moderate Altered Expression [796]
CAST OTBXZZGF moderate Biomarker [797]
CAVIN4 OTB1DM2C moderate Biomarker [798]
CBLN2 OT29SSBE moderate Biomarker [799]
CCL13 OTNX0JD0 moderate Altered Expression [800]
CCNQ OT183N7L moderate Biomarker [801]
CD2AP OTC76KQM moderate Altered Expression [802]
CEBPZ OT11BATG moderate Biomarker [803]
CFHR1 OT72R16T moderate Genetic Variation [804]
CHRNA3 OTCZQY1U moderate Genetic Variation [805]
CIRBP OTXWTPBL moderate Biomarker [806]
CLC OTYMYR85 moderate Genetic Variation [206]
CLDN7 OTNE0XHQ moderate Altered Expression [807]
CLEC16A OTLGV5SV moderate Genetic Variation [808]
CLOCK OTNEOJY7 moderate Biomarker [661]
CNTN4 OTULXVE0 moderate Altered Expression [809]
COL21A1 OT7GS82E moderate Genetic Variation [358]
COL9A1 OTWBR27Y moderate Biomarker [235]
COL9A2 OT1ZBDBV moderate Biomarker [235]
COL9A3 OTCUJOEK moderate Biomarker [235]
COMP OTS2FPMI moderate Biomarker [235]
CORO1A OTVAZOHC moderate Biomarker [810]
CPOX OTIAY121 moderate Biomarker [85]
CTBP1 OTVYH2DH moderate Biomarker [811]
CTRL OTB6NA5O moderate Biomarker [812]
CXCL5 OTZOUPCA moderate Biomarker [813]
DAB2 OTRMQTMZ moderate Biomarker [814]
DAPK2 OTWODUQG moderate Biomarker [611]
DNM3 OTDMUGCR moderate Biomarker [809]
DPAGT1 OTYEJAGZ moderate Altered Expression [815]
DRAM1 OTIJTXEN moderate Genetic Variation [816]
DUOX1 OTQ2AEW0 moderate Altered Expression [696]
DUOX2 OTU14HCN moderate Altered Expression [696]
EBF3 OTB0IWLW moderate Biomarker [817]
EFNB2 OT0DCUOM moderate Biomarker [818]
ENO3 OT3HYKYI moderate Biomarker [819]
ETV5 OTE2OBM4 moderate Genetic Variation [820]
FAIM2 OT6QINVO moderate Genetic Variation [659]
FAM78B OTIY35CP moderate Genetic Variation [217]
FBLN2 OTEHR7N7 moderate Biomarker [821]
FGA OTMIHY80 moderate Genetic Variation [822]
FHL2 OT0OAYWT moderate Biomarker [823]
FHOD3 OT1WUBQX moderate Altered Expression [824]
FIG4 OT501PY9 moderate Genetic Variation [825]
FIS1 OT2HL10J moderate Biomarker [826]
FLVCR1 OT9XCFOC moderate Biomarker [827]
FNDC5 OT5CSK9X moderate Biomarker [828]
FOXN1 OTE80D6I moderate Altered Expression [829]
FZD4 OTGLZIE0 moderate Biomarker [185]
GAL3ST1 OTSFFZRD moderate Altered Expression [830]
GALNT2 OTZZ5386 moderate Genetic Variation [831]
GLCCI1 OTU0R1CU moderate Genetic Variation [832]
GPR151 OT7EACU6 moderate Biomarker [185]
GPR162 OTK4LT3K moderate Biomarker [833]
GPR37L1 OTOV08EV moderate Biomarker [834]
GRK6 OT4LZTP9 moderate Biomarker [835]
GSTM2 OTG4WT05 moderate Genetic Variation [836]
GUCY1A1 OTPTCBUN moderate Biomarker [186]
HAP1 OT6SG0JQ moderate Biomarker [145]
HBA1 OTW2BQF4 moderate Biomarker [187]
HDHD2 OTNO5X2M moderate Biomarker [837]
HLTF OTRX2OSF moderate Altered Expression [838]
HOMER1 OTWFD3SI moderate Altered Expression [171]
HPX OT14T7Q1 moderate Biomarker [427]
HSPA1L OTC2V1K6 moderate Genetic Variation [839]
HSPA2 OTSDET7B moderate Genetic Variation [839]
HTN1 OTH3W1RR moderate Altered Expression [840]
IFIH1 OTZA2AHA moderate Altered Expression [841]
IFNL2 OT4BMJF7 moderate Biomarker [800]
IL10RA OTOX3D1D moderate Biomarker [195]
KLF15 OTGMQMVR moderate Altered Expression [842]
KRT5 OTVGI9HT moderate Biomarker [843]
L3MBTL4 OTERBGKR moderate Genetic Variation [844]
LAT2 OTWJDKIH moderate Genetic Variation [845]
LGR6 OTPZ1PWR moderate Biomarker [185]
LLGL2 OTU8ZDC4 moderate Genetic Variation [217]
LYPLAL1 OT8F2DCV moderate Genetic Variation [820]
MCU OTQZAYWQ moderate Genetic Variation [846]
MEPE OTXJRUW0 moderate Genetic Variation [847]
MINDY4 OTBZ2SZB moderate Biomarker [298]
MOV10 OT0KAY9G moderate Genetic Variation [156]
MRGPRX3 OTRKCCDS moderate Biomarker [185]
MRGPRX4 OTOBHZVA moderate Biomarker [185]
MTA2 OTCCYIQJ moderate Biomarker [848]
MVP OTJGHJRB moderate Biomarker [849]
MYL2 OT78PC0C moderate Genetic Variation [850]
MYOCD OTSJNHTH moderate Biomarker [851]
ND1 OTCLGIXV moderate Genetic Variation [852]
NDUFA10 OTBURQ3A moderate Genetic Variation [853]
NECTIN1 OTTE5ZR6 moderate Biomarker [854]
NFU1 OTL58QZS moderate Genetic Variation [855]
NGB OTW0SIUY moderate Genetic Variation [856]
NPBWR1 OTN8NRXK moderate Biomarker [857]
NPC1 OTRIPICX moderate Genetic Variation [659]
NPW OTO7MT28 moderate Biomarker [857]
NREP OT2AZPKK moderate Altered Expression [250]
NSD2 OTQ6SW4R moderate Biomarker [858]
NT5C1A OTS7UF36 moderate Biomarker [859]
NUPR1 OT4FU8C0 moderate Altered Expression [860]
PAG1 OTFOJUIQ moderate Biomarker [861]
PAK3 OT80M3BV moderate Genetic Variation [862]
PC OT6O0V51 moderate Altered Expression [863]
PCBP4 OTDLL4NB moderate Biomarker [861]
PDC OT1UUVYY moderate Biomarker [864]
PHF14 OTZT3GV1 moderate Genetic Variation [865]
PIEZO1 OTBG1FU4 moderate Biomarker [866]
PIPOX OTWTCOTN moderate Genetic Variation [867]
PKD2 OTIXBU8H moderate Biomarker [727]
PLAG1 OTT9AJQY moderate Genetic Variation [210]
PLCE1 OTJISZOX moderate Genetic Variation [868]
PPP1CB OTYFTYFR moderate Posttranslational Modification [869]
PPP1R14A OTQODWZB moderate Altered Expression [870]
PPP1R9B OTDCTHTT moderate Biomarker [871]
PRF1 OTFVXD7H moderate Genetic Variation [872]
PRH1 OTQZ6HX0 moderate Biomarker [873]
PRKAA2 OTU1KZPV moderate Biomarker [874]
PRKAG2 OTHTAM54 moderate Altered Expression [875]
PRRC2A OTBX6FM5 moderate Genetic Variation [876]
PSD4 OTEFB87Z moderate Genetic Variation [877]
PTPN5 OT2H1KDK moderate Biomarker [878]
PXDN OTFGGM9R moderate Biomarker [879]
PXN OTVMMUOF moderate Altered Expression [880]
RABGEF1 OTWC3Z3R moderate Biomarker [881]
RAMP3 OTX6XLLM moderate Altered Expression [882]
RAP1A OT5RH6TI moderate Biomarker [881]
RAP1B OTHEIIMM moderate Biomarker [869]
RBFOX2 OTXY1WVH moderate Biomarker [883]
RBM47 OT6W67VM moderate Genetic Variation [358]
RCAN1 OT1MVXC7 moderate Genetic Variation [884]
REM1 OTUXL0HC moderate Biomarker [885]
RGCC OTYJMLWM moderate Altered Expression [886]
RGS1 OTGXJYMG moderate Biomarker [887]
RNPC3 OTW5MKC1 moderate Biomarker [888]
RPL13 OTFKNTD6 moderate Biomarker [190]
RPS6 OTT4D1LN moderate Altered Expression [531]
RPTOR OT4TQZ9F moderate Genetic Variation [156]
RRAS OTBBF28C moderate Genetic Variation [358]
RRS1 OTTNCZN6 moderate Biomarker [889]
RUBCNL OTMQIDOI moderate Biomarker [890]
RUNX1T1 OT30DED5 moderate Biomarker [656]
RXFP4 OTJRBOZP moderate Genetic Variation [891]
SACM1L OT6ORKTD moderate Genetic Variation [892]
SAP130 OT01SO0E moderate Biomarker [893]
SEMA3F OTQFMS8S moderate Genetic Variation [808]
SERPINA5 OTTZXPGD moderate Genetic Variation [894]
SF3B3 OTAC9LZT moderate Biomarker [893]
SMS OT8JYKNH moderate Biomarker [895]
SOX18 OTPUMHWA moderate Genetic Variation [896]
SRA1 OTYOGMTG moderate Genetic Variation [206]
STIM1 OT8CLQ1W moderate Biomarker [727]
STK25 OT4YPNTF moderate Biomarker [244]
TAF7L OTPDZ6XV moderate Biomarker [897]
TAS2R13 OTSTOX5G moderate Genetic Variation [898]
TASOR OTEAMOON moderate Biomarker [899]
TBX2 OTTOT7A9 moderate Genetic Variation [156]
TCEANC OTERP9MX moderate Genetic Variation [844]
TCOF1 OT4BOYTM moderate Biomarker [837]
TERF2IP OT3M5P3G moderate Biomarker [881]
TMEM11 OTL9HDEY moderate Biomarker [662]
TMEM54 OTPQEFR0 moderate Genetic Variation [794]
TOR2A OT1EGCDU moderate Biomarker [900]
TOX OTE8BL5Z moderate Genetic Variation [901]
TREML2 OTKQGKVJ moderate Genetic Variation [902]
TRIM67 OTXRZN27 moderate Biomarker [903]
TRIO OT71X1AK moderate Biomarker [904]
A2M OTFTX90K Strong Genetic Variation [905]
ABCG8 OTIJ76XW Strong Genetic Variation [906]
ACACA OT5CQPZY Strong Biomarker [907]
ACADSB OTDO6HBG Strong Genetic Variation [681]
ACCS OTHIHI9D Strong Genetic Variation [665]
ACTB OT1MCP2F Strong Biomarker [908]
ADAMTS16 OTTKUH99 Strong Biomarker [909]
ADAMTS18 OTRMFI04 Strong Biomarker [910]
ADD2 OTRCPCD2 Strong Genetic Variation [911]
ADIPOR1 OT65ZFZN Strong Biomarker [781]
AFG3L2 OTRPMAUX Strong CausalMutation [912]
AGAP1 OTVX8835 Strong Genetic Variation [913]
AGFG1 OTI8ZKC4 Strong Biomarker [914]
AGPS OTFBFPV4 Strong Genetic Variation [915]
AGTRAP OT02N7LD Strong Biomarker [916]
AGXT2 OTO6QUTM Strong Biomarker [917]
AKAP10 OTPNFTOU Strong Genetic Variation [918]
ALDH7A1 OTV57BZD Strong Genetic Variation [919]
ALOX15B OTWQQ08W Strong Biomarker [920]
AMH OT5FH4BD Strong Genetic Variation [921]
AMY1A OT6G4B8O Strong Biomarker [922]
APBB1IP OTN02KUV Strong Genetic Variation [923]
APCDD1 OTV9AD0L Strong Biomarker [924]
APOA5 OTEVKLVA Strong Genetic Variation [925]
APOC1 OTA58CED Strong Biomarker [926]
AQP2 OTQLBKK6 Strong Altered Expression [927]
ARF6 OTVV7KJO Strong Biomarker [928]
ARHGAP42 OTIDSJMK Strong Biomarker [929]
ARHGAP6 OTNVXXFX Strong Altered Expression [534]
ARHGEF25 OT7162TD Strong Altered Expression [930]
ARHGEF28 OT3F32IU Strong Biomarker [931]
ARHGEF40 OTFSKXG9 Strong Biomarker [932]
ARID1B OTILK3Q7 Strong Genetic Variation [933]
ARID3A OTZZ4SFP Strong Genetic Variation [933]
ARMS2 OTUXHJ9H Strong Genetic Variation [934]
ARSD OTAHW9M8 Strong Biomarker [935]
ARSL OTF1VTCR Strong Biomarker [446]
ARTN OTWIWGL6 Strong Biomarker [279]
ATOX1 OT05LF59 Strong Therapeutic [936]
ATP1B1 OTTO6ZP4 Strong Biomarker [937]
ATP2B2 OT1NPZ9T Strong Genetic Variation [938]
ATP2B3 OT9DIEOP Strong Genetic Variation [938]
ATP2B4 OTMWFDAC Strong Biomarker [939]
ATP5F1B OTLFZUQK Strong Biomarker [940]
ATP6V0A1 OT1IK0KA Strong Biomarker [941]
B3GAT1 OTXFP98E Strong Biomarker [942]
BAG6 OT4Z0S2U Strong Genetic Variation [389]
BCAP31 OTKSACR4 Strong Genetic Variation [943]
BGLAP OTK1YLWQ Strong Genetic Variation [944]
BHLHE41 OTY9GJ1Y Strong Altered Expression [945]
BMPER OTBYON4H Strong Biomarker [946]
BMPR1A OTQOA4ZH Strong Altered Expression [947]
BMS1 OTEGQ8ZO Strong Biomarker [907]
BNIP1 OT7USYCY Strong Biomarker [948]
BORCS7 OTQUOZC2 Strong Genetic Variation [156]
BPIFB4 OTHF0EOJ Strong Genetic Variation [949]
BRCA1 OT5BN6VH Strong Biomarker [532]
BST1 OTAV5SE7 Strong Genetic Variation [950]
BTBD8 OT3A3RD7 Strong Biomarker [951]
BTG3 OT9ANHVT Strong Biomarker [952]
BTN2A1 OTUYPMZJ Strong Biomarker [217]
BTNL2 OTTTEMZA Strong Altered Expression [953]
C1QL1 OTNQ0G3E Strong Biomarker [341]
C1QTNF1 OT7I7KHC Strong Biomarker [954]
C1QTNF3 OTOJMWW0 Strong Altered Expression [955]
CABIN1 OT4G5CIK Strong Biomarker [443]
CALD1 OTNJKJ6Q Strong Genetic Variation [943]
CAPN10 OTS9LJW4 Strong Genetic Variation [956]
CAPZA1 OTAXA66U Strong Genetic Variation [156]
CASQ2 OT09MNQ8 Strong Genetic Variation [957]
CASZ1 OTWJ2OR8 Strong Genetic Variation [958]
CAV3 OTWSFDB4 Strong Altered Expression [959]
CCL28 OTY6XNQ7 Strong Biomarker [800]
CCN4 OT69BER9 Strong Genetic Variation [960]
CCNL2 OT0NIKYM Strong Biomarker [801]
CD164L2 OT0LZOPP Strong Genetic Variation [961]
CD5L OTPY4WQR Strong Biomarker [327]
CDH13 OTD2CYM5 Strong Genetic Variation [962]
CDH18 OTC06P9H Strong Genetic Variation [412]
CDKAL1 OTA0SGNE Strong Genetic Variation [963]
CDSN OTQW4HV6 Strong Biomarker [964]
CELA2A OTY8QG2J Strong Biomarker [965]
CERS5 OT5A2DNI Strong Genetic Variation [358]
CHCHD5 OTVESFOA Strong Biomarker [966]
CHGA OTXYX5JH Strong Biomarker [967]
CHGB OT7SAQT2 Strong Genetic Variation [968]
CISD2 OTVS7S2H Strong Genetic Variation [969]
CLIC4 OT6KTPKD Strong Biomarker [928]
CLTRN OTXGFJ3F Strong Altered Expression [970]
CMYA5 OTYV0RME Strong Biomarker [971]
CNBP OTTGM9NK Strong Altered Expression [972]
CNN1 OTVPG39Z Strong Biomarker [702]
CNNM2 OTZHO8WU Strong Genetic Variation [973]
CNTN3 OTC1274J Strong Genetic Variation [974]
CNTN5 OTWU5FLZ Strong Biomarker [975]
CNTNAP2 OT48T2ZP Strong Genetic Variation [976]
COL17A1 OTID5AH2 Strong Genetic Variation [98]
COL1A1 OTI31178 Strong Biomarker [977]
COL3A1 OTT1EMLM Strong Genetic Variation [978]
COL4A1 OTL6D1YE Strong Genetic Variation [979]
COL4A2 OTJK1LKN Strong Biomarker [980]
COL6A5 OTJT8O80 Strong Genetic Variation [271]
COL8A1 OTWBTED2 Strong Genetic Variation [981]
COMMD5 OT6R7DXN Strong Biomarker [982]
COX8A OTU0NR39 Strong Biomarker [85]
CPQ OTTNZNLD Strong Biomarker [983]
CRIP3 OT7H1YOY Strong Genetic Variation [156]
CRISP2 OT8HLTV5 Strong Biomarker [583]
CSMD1 OTIVDSC4 Strong Biomarker [984]
CST3 OTNZ6AO4 Strong Biomarker [985]
CUX2 OTDJTQAJ Strong Genetic Variation [156]
CYGB OTX153DQ Strong Altered Expression [986]
DCP1B OTX7PHCI Strong Biomarker [987]
DDX53 OTHK3EGZ Strong Genetic Variation [988]
DEGS1 OT4WXPKW Strong Biomarker [989]
DENR OTXP9HOY Strong Biomarker [611]
DHX40 OTOL02QN Strong Biomarker [501]
DLEU7 OTVKX1YP Strong Genetic Variation [990]
DNAAF1 OTYLQLHO Strong Genetic Variation [991]
DNM1L OTXK1Q1G Strong Biomarker [611]
DNTT OTFSEF12 Strong Biomarker [992]
DROSHA OTCE68KZ Strong Genetic Variation [993]
DSC3 OTYG47F8 Strong Biomarker [994]
DST OTHZBM4X Strong Genetic Variation [995]
DUSP2 OTH54FMR Strong Biomarker [270]
DYM OTQ670WI Strong Biomarker [310]
EDN3 OTN7Q9BE Strong Biomarker [996]
EFEMP1 OTZVUOOB Strong Biomarker [997]
EFNB1 OT7JJW8P Strong Biomarker [998]
EFNB3 OT12WTXQ Strong Biomarker [998]
ELN OTFSO7PG Strong Biomarker [999]
EMD OTR8ZANE Strong Biomarker [1000]
EML6 OTE1MUQS Strong Genetic Variation [156]
ENHO OT91QASK Strong Biomarker [1001]
ERAL1 OTSH78HD Strong Biomarker [1002]
ERCC3 OTVAW3P1 Strong Altered Expression [1003]
ETV3 OTEN03BM Strong Biomarker [1004]
EXOSC10 OTH8Z0AL Strong Biomarker [1005]
EYA3 OTHLP1J3 Strong Altered Expression [1006]
FAM20C OTW5YZ7X Strong Biomarker [1007]
FBL OTRODIE5 Strong Biomarker [1008]
FBN1 OTYCJT63 Strong Biomarker [1009]
FCN3 OTPRENLS Strong Genetic Variation [961]
FGB OT6RKLI9 Strong Genetic Variation [1010]
FGD4 OTYXJQCW Strong Genetic Variation [156]
FGD5 OT5VIRP2 Strong Genetic Variation [1011]
FOXRED1 OTYEB8YK Strong Genetic Variation [1012]
FRMD3 OT0CD2GG Strong Genetic Variation [412]
FSD1 OT8P6PT3 Strong Biomarker [1013]
FSD1L OTBQ48RF Strong Biomarker [1013]
GABPA OT9YB2SA Strong Genetic Variation [478]
GATA5 OTO81B63 Strong Biomarker [1014]
GCA OTAJ7ZHG Strong Biomarker [1015]
GHRH OT94U6MO Strong Genetic Variation [576]
GML OTHKIB62 Strong Genetic Variation [156]
GNA12 OT3IRZH3 Strong Biomarker [1016]
GNA14 OTYZ1ZI0 Strong Biomarker [1017]
GNAI2 OTTLGRGH Strong Genetic Variation [1018]
GOLPH3 OTDLGYM3 Strong Biomarker [711]
GOT2 OT6XBWN0 Strong Genetic Variation [1019]
GPR42 OTEB0ROY Strong Biomarker [265]
GPR75 OT8SPUGC Strong Biomarker [1020]
GREB1 OTU6ZA26 Strong Biomarker [1021]
GRHL1 OTZ4MNEW Strong Biomarker [1022]
GRK4 OTUU8V2S Strong Biomarker [1023]
GSTA5 OTG7ID8U Strong Biomarker [108]
GSTCD OTIIINMT Strong Biomarker [51]
GSTM3 OTLA2WJT Strong Genetic Variation [1024]
GSTM5 OTMMBFY8 Strong Genetic Variation [1025]
GSTT2 OTANW3TJ Strong Biomarker [108]
GUCA2B OTZERX04 Strong Genetic Variation [1026]
GYPA OTABU4YV Strong Genetic Variation [1027]
GYPB OTESHUIX Strong Genetic Variation [1027]
GYPE OTBHAG6A Strong Genetic Variation [1027]
GYS1 OTJZJRWK Strong Genetic Variation [1028]
H2AX OT18UX57 Strong Therapeutic [532]
HBG2 OT4J48JJ Strong Biomarker [1029]
HEY1 OTJQL0I3 Strong Biomarker [539]
HNRNPD OT5UO1FA Strong Biomarker [1030]
HOPX OTBSR6C9 Strong Biomarker [334]
HOXA3 OTIX5XFB Strong Genetic Variation [412]
HOXB7 OTC7WYU8 Strong Genetic Variation [358]
HPCAL1 OTOBBFRD Strong Biomarker [1021]
HTN3 OTEUXA81 Strong Biomarker [1031]
IER3 OTZJI5FZ Strong Biomarker [1032]
IGF2BP2 OT4ZSEEE Strong Genetic Variation [963]
IKZF5 OTJN51OC Strong Genetic Variation [1033]
ILF3 OTKMZ5K5 Strong Genetic Variation [1034]
IMPACT OTQ923OB Strong Biomarker [1035]
INHA OT7HWCO3 Strong Biomarker [1036]
INSRR OT3F75WA Strong Genetic Variation [1037]
ISYNA1 OT49ONSE Strong Genetic Variation [1038]
ITGB1BP2 OTHYX9F3 Strong Genetic Variation [1039]
ITM2B OTMXEPXB Strong Biomarker [108]
JAG1 OT3LGT6K Strong Biomarker [1040]
JPH3 OTHTJO2I Strong Biomarker [1041]
KALRN OT8WRCBH Strong Genetic Variation [1042]
KCNMB1 OTO4KNJ4 Strong Genetic Variation [1043]
KIF2B OTLPAX4N Strong Genetic Variation [1044]
KIR2DS5 OTXLEN11 Strong Biomarker [1045]
KL OTD4VWU6 Strong Altered Expression [1046]
KLHL29 OTS5Z1QN Strong Genetic Variation [1047]
KLK12 OTNYK59J Strong Biomarker [1048]
KLK9 OTGJWBIF Strong Biomarker [952]
KNSTRN OTYA7UXS Strong Biomarker [1049]
KRT16 OTGA0EQN Strong Genetic Variation [1050]
KRT8 OTTM4X11 Strong Biomarker [328]
LCE1C OTQY73YS Strong Biomarker [1051]
LCN1 OT8BWXTV Strong Altered Expression [1052]
LDOC1 OTWZH4O9 Strong Biomarker [948]
LHB OT5GBOVJ Strong Biomarker [409]
LIPC OTZY5SC9 Strong Genetic Variation [1053]
LMNA OT3SG7ZR Strong Altered Expression [1054]
LPIN1 OTQ75KF2 Strong Genetic Variation [1055]
LRPAP1 OT6DVD2Q Strong Biomarker [1056]
LRRC10B OT9NKWFW Strong Genetic Variation [156]
LSP1 OTSPSIFO Strong Genetic Variation [156]
MACROD2 OTNQCHC6 Strong Genetic Variation [414]
MAP3K15 OT1E21HI Strong Biomarker [1057]
MAP6 OTPUI00F Strong Genetic Variation [1058]
MAP9 OTZD5099 Strong Genetic Variation [1059]
MARCHF8 OTH7PNN2 Strong Genetic Variation [1060]
MBD2 OTUQPP0R Strong Altered Expression [1061]
MCAT OTH07FIW Strong Biomarker [329]
MCM3AP OT895FEC Strong Genetic Variation [825]
MCPH1 OTYT3TT5 Strong Biomarker [329]
MDH1 OTJEO4E8 Strong Biomarker [108]
MED23 OTKZQT0R Strong Biomarker [1062]
MEF2A OTV2SF6E Strong Biomarker [1063]
MEST OT8Q4U8Y Strong Biomarker [401]
MEX3C OT8AJG1I Strong Biomarker [1064]
MFAP1 OTZN4FT3 Strong Biomarker [667]
MFN2 OTPYN8A3 Strong Biomarker [1065]
MICALL2 OT1IQM3K Strong Genetic Variation [958]
MKKS OTLF5T11 Strong Genetic Variation [1066]
MLXIP OT30UNI7 Strong Genetic Variation [1060]
MMD OTB5I4OC Strong Biomarker [1067]
MOB3C OT2OFNGF Strong Biomarker [271]
MOK OTQK7M9V Strong Altered Expression [21]
MPI OTBH6ZK1 Strong Biomarker [1068]
MPV17 OT579DMU Strong Biomarker [1069]
MRAP2 OTCQS7DB Strong Genetic Variation [1070]
MTHFD1 OTMKHVWC Strong Posttranslational Modification [1071]
MTMR9 OTGCBJHD Strong Genetic Variation [1072]
MX1 OT6X8G5T Strong Altered Expression [1073]
MYH6 OT3YNCH1 Strong Biomarker [1074]
MYL3 OTKD3RSX Strong Biomarker [1075]
MYLIP OTL0PFGV Strong Genetic Variation [1060]
MYO6 OTJQYRC7 Strong Biomarker [1076]
MYO9B OTQ94R5K Strong Genetic Variation [156]
NBEAL2 OTMCAXWR Strong Biomarker [1077]
NCDN OT5CE7LO Strong Biomarker [328]
NCF2 OTAUW7L2 Strong Biomarker [1078]
ND2 OTG9OHOX Strong Genetic Variation [1079]
NDFIP2 OT34DCAP Strong Genetic Variation [610]
NEDD4L OT1B19RU Strong Genetic Variation [1080]
NEFH OTMSCW5I Strong Biomarker [1081]
NFAT5 OTKIE59S Strong Genetic Variation [1082]
NFATC2 OTK5T6HZ Strong Genetic Variation [156]
NFATC3 OTYOORME Strong Biomarker [1083]
NFIL3 OTQH9HM3 Strong Biomarker [1084]
NFYA OTWFFOVH Strong Altered Expression [145]
NKX2-5 OTS1SAWM Strong Biomarker [1085]
NLRC3 OTWLLFFN Strong Biomarker [1086]
NLRP6 OTEREN4W Strong Genetic Variation [1087]
NOG OTGRHHPG Strong Biomarker [245]
NOVA2 OTQ2X3Q4 Strong Biomarker [1088]
NOX3 OT0FFJH8 Strong Genetic Variation [1089]
NOX5 OTHTH59G Strong Biomarker [1090]
NPAS2 OTMRT2TS Strong Biomarker [945]
NPHS1 OT21JD3P Strong Genetic Variation [1091]
NPL OTA7P0TO Strong Genetic Variation [1092]
NPTN OTAQKSAU Strong Biomarker [108]
NPTXR OTQJEOIH Strong Genetic Variation [1093]
NTS OTPGDNQS Strong Genetic Variation [618]
OGN OTKP5S4L Strong Biomarker [1094]
OPN1LW OTFNUZ7O Strong Biomarker [861]
OR10A4 OTYYB8SY Strong Biomarker [1095]
OR5B12 OTCGNJVZ Strong Genetic Variation [358]
OSER1 OTN8C6JQ Strong Biomarker [76]
OSR1 OTB19LEQ Strong Biomarker [76]
P2RX6 OT1FNTXA Strong Genetic Variation [497]
P3H4 OTZPXYSH Strong Biomarker [1096]
PADI1 OT13WAQX Strong Biomarker [1097]
PAQR7 OTIWX5AM Strong Genetic Variation [555]
PDIA2 OTC2WMXS Strong Biomarker [1097]
PDLIM5 OTLQVV22 Strong Genetic Variation [1098]
PEAR1 OT2XLTB2 Strong Biomarker [1099]
PFN1 OTHTGA1H Strong Biomarker [997]
PHEX OTG7N3J7 Strong Biomarker [1100]
PHOX2A OTVS3R2X Strong Genetic Variation [1101]
PITX2 OTWMXAOY Strong Biomarker [1102]
PKD1 OT5ALRZ5 Strong Genetic Variation [1103]
PLA2G15 OT6VJTPA Strong Genetic Variation [665]
PLCD1 OT6WFVXZ Strong Biomarker [1104]
PLEKHA7 OTNUMAZ0 Strong Genetic Variation [1105]
PLEKHG1 OTDVYW2F Strong Genetic Variation [412]
PLEKHH2 OT3TK3NN Strong Genetic Variation [584]
PLXNA2 OTNNBJMQ Strong Biomarker [1106]
PLXNA3 OTMZIBVG Strong Biomarker [1107]
PODXL OTPNQXF3 Strong Altered Expression [1108]
POLI OTBA4DCE Strong Genetic Variation [1109]
PPBP OT1FHGQS Strong Biomarker [1110]
PPIG OTZ8BTTM Strong Altered Expression [1111]
PPL OTTM4WDO Strong Genetic Variation [1112]
PPP3R1 OTGQNFJQ Strong Biomarker [1113]
PPP6R2 OTERHESI Strong Biomarker [1114]
PRKAA1 OT7TNF0L Strong Biomarker [874]
PRKAB1 OT1OG4QZ Strong Biomarker [874]
PRRX1 OTTZK5G8 Strong Genetic Variation [923]
PRSS55 OTXXWI5Y Strong Biomarker [583]
PSG5 OTHTU98X Strong Genetic Variation [1115]
PSMD9 OT6Y5CC3 Strong Altered Expression [1116]
PSMG1 OTZ5I6UM Strong Biomarker [270]
PSTK OTA5UXAX Strong Genetic Variation [1033]
PTPA OTRGFOI7 Strong Altered Expression [360]
PTPMT1 OT9WVC6N Strong Genetic Variation [678]
PTPRD OTZPJ3GX Strong Biomarker [575]
PTPRO OTFLKWOY Strong Biomarker [1117]
PTPRU OTHDO0QG Strong Genetic Variation [1118]
PTX3 OTPXHRKU Strong Altered Expression [1119]
RABGAP1L OT7QO47I Strong Genetic Variation [1120]
RAC2 OTAOHFNH Strong Genetic Variation [1121]
RAG1 OTV131E4 Strong Biomarker [1122]
RAMP1 OT7UT2XB Strong Biomarker [1123]
RAMP2 OTGQXLH5 Strong Biomarker [882]
RBM8A OT5SR6G0 Strong Biomarker [1124]
RCN2 OTIU8JWD Strong Biomarker [1125]
REG3G OTLIUY8Z Strong Biomarker [1126]
RELA OTUJP9CN Strong Biomarker [1127]
RETN OTW5Z1NH Strong Biomarker [1128]
RETNLB OT9JJQQQ Strong Biomarker [1129]
RFC1 OT3L5PK3 Strong Genetic Variation [1130]
RGL3 OTWZ30EZ Strong Genetic Variation [678]
RGS20 OT6CGYHW Strong Genetic Variation [1131]
RGS5 OTUY0Q2I Strong Altered Expression [1132]
RHOBTB1 OTGE8K45 Strong Biomarker [1133]
RHOD OTALMEIN Strong Altered Expression [538]
RLN1 OTL6QNHG Strong Biomarker [1134]
RLN2 OTY3OG71 Strong Biomarker [1135]
RNGTT OT59E0KX Strong Altered Expression [1136]
ROPN1 OTPXKZTX Strong Genetic Variation [1042]
RYR2 OT0PF19E Strong Altered Expression [1137]
RYR3 OT4EHIP4 Strong Genetic Variation [1138]
SARDH OTQ49Q27 Strong Biomarker [573]
SCG2 OTXWUQQL Strong Genetic Variation [1101]
SCNN1B OT61QQTL Strong Genetic Variation [401]
SCPEP1 OT43LYEZ Strong Genetic Variation [1139]
SDHB OTRE1M1T Strong Genetic Variation [258]
SDHC OTC8G2MX Strong Genetic Variation [1140]
SDK1 OTX26906 Strong Biomarker [1120]
SDS OT5WTJ2M Strong Genetic Variation [1141]
SEMA6A OTDQ7QAW Strong Biomarker [1111]
SEMA7A OT0ZJK64 Strong Biomarker [1142]
SEPHS1 OTZ19I59 Strong Biomarker [1143]
SERPINA7 OTUYVTSU Strong Biomarker [1144]
SERPINB2 OT72QLZB Strong Biomarker [1145]
SERPINF2 OTZGAF8B Strong Biomarker [1146]
SESN2 OT889IXY Strong Biomarker [64]
SESTD1 OTHH06X8 Strong Biomarker [932]
SETD3 OTO5RAU2 Strong Biomarker [1147]
SFRP5 OTLCVVSH Strong Altered Expression [623]
SFTPC OTIZJD09 Strong Altered Expression [1148]
SGCZ OTVGTEOD Strong Genetic Variation [991]
SGSM3 OTIB1P8A Strong Biomarker [1149]
SH2B1 OTJZO2CI Strong Biomarker [1150]
SHC1 OT1J5IRN Strong Genetic Variation [1151]
SHMT1 OTIINA3J Strong Biomarker [1152]
SLC12A9 OTR7VRAK Strong Genetic Variation [1047]
SLPI OTUNFUU8 Strong Biomarker [137]
SMTN OT4R2TYK Strong Biomarker [1153]
SNAI1 OTDPYAMC Strong Biomarker [1154]
SNX1 OTXQSJ1J Strong Biomarker [1155]
SNX5 OT6ZOWMU Strong Altered Expression [434]
SOD3 OTIOZQAB Strong Altered Expression [1156]
SORBS1 OTWH8762 Strong Genetic Variation [1157]
SPRR2A OT62ZU6B Strong Genetic Variation [1158]
SPZ1 OTQH8HJ5 Strong Biomarker [583]
SRF OTW18FQN Strong Biomarker [307]
SRGAP3 OT9ZS72C Strong Genetic Variation [1159]
SRM OT4N5MDP Strong Biomarker [1143]
SRXN1 OTYDBO4L Strong Biomarker [1160]
ST3GAL4 OTNENJZQ Strong Biomarker [1161]
STK11 OT1YZSP3 Strong Altered Expression [474]
STK24 OTGUHOIL Strong Biomarker [1162]
STK3 OTLNSCQD Strong Genetic Variation [412]
STN1 OT8UWRA3 Strong Genetic Variation [358]
STOX1 OTED3YVO Strong Biomarker [1163]
STUB1 OTSUYI9A Strong Biomarker [1164]
SVEP1 OTOBICRD Strong Genetic Variation [1165]
SWAP70 OTPHT2QD Strong Genetic Variation [156]
TAC1 OTM842YW Strong Biomarker [484]
TAC3 OTOJGM38 Strong Altered Expression [1166]
TAF1C OTNV4CDH Strong Genetic Variation [991]
TAS2R38 OTX5MM36 Strong Genetic Variation [1167]
TBX1 OTQLBPRA Strong Biomarker [1168]
TBX3 OTM64N7K Strong Biomarker [1169]
TBX4 OTW58FG4 Strong Genetic Variation [1170]
TBX5 OT70PISV Strong Biomarker [1169]
TET2 OTKKT03T Strong Genetic Variation [1164]
TFG OT2KJENI Strong Altered Expression [1171]
TGFBRAP1 OT80QNR5 Strong Biomarker [1172]
THBS4 OTA1T9KK Strong Biomarker [1173]
TIMP1 OTOXC51H Strong Biomarker [1174]
TLX2 OTPFAUM8 Strong Altered Expression [243]
TMEM212 OTTWVUDE Strong Genetic Variation [923]
TMEM38A OT7336MZ Strong Genetic Variation [1175]
TNXB OTVBWAV5 Strong Genetic Variation [1176]
TPD52 OTPKSK43 Strong Genetic Variation [1050]
TPM1 OTD73X6R Strong Biomarker [108]
TRAM1 OT3I0H8E Strong Altered Expression [1177]
TRIB3 OTG5OS7X Strong Genetic Variation [898]
TRIM47 OTM9DGUD Strong Genetic Variation [1178]
TRPV5 OTWF4L0U Strong Genetic Variation [1179]
TTC21B OTXXA87U Strong Genetic Variation [1180]
APBB1 OTZPVSSC Definitive Biomarker [1181]
BEST1 OTWHE1ZC Definitive Biomarker [1182]
CARD8 OTXXZYWU Definitive Genetic Variation [1183]
HBG1 OTVL4NSU Definitive Biomarker [1029]
HSPA4 OT5HR0AR Definitive Biomarker [1184]
MCIDAS OTK1JVAH Definitive Biomarker [1185]
MYH11 OTVNVWY3 Definitive Altered Expression [1186]
RNF213 OT4OVE9O Definitive Genetic Variation [1187]
------------------------------------------------------------------------------------
⏷ Show the Full List of 731 DOT(s)

References

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3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7125).
4 Chlorthalidone FDA Label
5 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7179).
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7 Irbesartan FDA Label
8 Lisinopril FDA Label
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10 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2559).
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14 Triamterene FDA Label
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27 Is renal tubular cadmium toxicity clinically relevant?.Clin Kidney J. 2018 Oct;11(5):681-687. doi: 10.1093/ckj/sfx153. Epub 2018 Feb 2.
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29 Different cell cycle regulation of vascular smooth muscle in genetic hypertension.Hypertension. 2003 Aug;42(2):184-8. doi: 10.1161/01.HYP.0000082360.65547.7C. Epub 2003 Jul 7.
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33 The association between circulating endostatin and a disturbed circadian blood pressure pattern in patients with type 2 diabetes.Blood Press. 2018 Aug;27(4):215-221. doi: 10.1080/08037051.2018.1444941. Epub 2018 Feb 28.
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35 Role of the immune system in vascular function and blood pressure control induced by faecal microbiota transplantation in rats.Acta Physiol (Oxf). 2019 Sep;227(1):e13285. doi: 10.1111/apha.13285. Epub 2019 Jun 2.
36 Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II.Blood. 2011 Oct 27;118(17):4750-8. doi: 10.1182/blood-2011-05-347393. Epub 2011 Sep 7.
37 Chronic inhibition of chemokine receptor CXCR2 attenuates cardiac remodeling and dysfunction in spontaneously hypertensive rats.Biochim Biophys Acta Mol Basis Dis. 2019 Dec 1;1865(12):165551. doi: 10.1016/j.bbadis.2019.165551. Epub 2019 Sep 5.
38 Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: a prospective analysis of up to 347,077 individuals and 8368 cases.Am J Clin Nutr. 2019 Mar 1;109(3):509-516. doi: 10.1093/ajcn/nqy297.
39 Dopamine D(3) receptors and salt-dependent hypertension.J Am Soc Nephrol. 2001 Nov;12(11):2272-2279. doi: 10.1681/ASN.V12112272.
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41 Dual-specificity phosphatase (DUSP) genetic variants predict pulmonary hypertension in patients with bronchopulmonary dysplasia.Pediatr Res. 2020 Jan;87(1):81-87. doi: 10.1038/s41390-019-0502-9. Epub 2019 Jul 22.
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43 ERRgamma regulates cardiac, gastric, and renal potassium homeostasis.Mol Endocrinol. 2010 Feb;24(2):299-309. doi: 10.1210/me.2009-0114. Epub 2009 Dec 4.
44 Evaluation of plasma levels of tissue factor and tissue factor pathway inhibitor in patients with psoriasis.Postepy Dermatol Alergol. 2019 Aug;36(4):442-448. doi: 10.5114/ada.2019.87447. Epub 2019 Aug 30.
45 Supplementation With the Sialic Acid Precursor N-Acetyl-D-Mannosamine Breaks the Link Between Obesity and Hypertension.Circulation. 2019 Dec 10;140(24):2005-2018. doi: 10.1161/CIRCULATIONAHA.119.043490. Epub 2019 Oct 10.
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67 Impact of long-term antihypertensive and antidiabetic medications on the prognosis of post-surgical colorectal cancer: the Fujian prospective investigation of cancer (FIESTA) study.Aging (Albany NY). 2018 May 24;10(5):1166-1181. doi: 10.18632/aging.101459.
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69 Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy.Environ Int. 2019 Feb;123:318-324. doi: 10.1016/j.envint.2018.11.047. Epub 2018 Dec 14.
70 Functional adrenocorticotropic hormone receptor in cultured human vascular endothelial cells : possible role in control of blood pressure. Hypertension. 2000 Nov;36(5):862-5.
71 Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects.Free Radic Biol Med. 2019 Jan;130:234-243. doi: 10.1016/j.freeradbiomed.2018.11.002. Epub 2018 Nov 3.
72 Assessment of potential predictors of calretinin and mesothelin to improve the diagnostic performance to detect malignant mesothelioma: results from a population-based cohort study.BMJ Open. 2017 Oct 11;7(10):e017104. doi: 10.1136/bmjopen-2017-017104.
73 Lack of association of interleukin-1 gene cluster polymorphisms with angiographically documented coronary artery disease: demonstration of association with hypertension in the Polish population.Arch Med Res. 2011 Jul;42(5):426-32. doi: 10.1016/j.arcmed.2011.08.002. Epub 2011 Aug 12.
74 Membrane trafficking of NADPH oxidase p47(phox) in paraventricular hypothalamic neurons parallels local free radical production in angiotensin II slow-pressor hypertension.J Neurosci. 2013 Mar 6;33(10):4308-16. doi: 10.1523/JNEUROSCI.3061-12.2013.
75 Mutation of low affinity nerve growth factor receptor gene is associated with the hypertensive phenotype in spontaneously hypertensive inbred rat strains.Neurosci Lett. 1996 May 24;210(1):69-72. doi: 10.1016/0304-3940(96)12664-1.
76 Association of OSR-1 With Vascular Dysfunction and Hypertension in Polycystic Kidney Disease.Ther Apher Dial. 2020 Feb;24(1):64-71. doi: 10.1111/1744-9987.12814. Epub 2019 Jul 4.
77 Long noncoding RNA-dependent regulation of vascular smooth muscle cell proliferation and migration in hypertension.Int J Biochem Cell Biol. 2020 Jan;118:105653. doi: 10.1016/j.biocel.2019.105653. Epub 2019 Nov 16.
78 The angiotensin I-converting enzyme inhibitor, cilazapril inhibits the platelet-derived growth factor B chain expression in glomeruli of spontaneously hypertensive rats.Ren Physiol Biochem. 1995 Sep-Oct;18(5):237-45. doi: 10.1159/000173921.
79 Identification of platelet-derived growth factor C as a mediator of both renal fibrosis and hypertension.Kidney Int. 2019 May;95(5):1103-1119. doi: 10.1016/j.kint.2018.11.031. Epub 2019 Feb 28.
80 PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension.Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13394-13403. doi: 10.1073/pnas.1821401116. Epub 2019 Jun 18.
81 Anandamide-nanoformulation obtained by electrospraying for cardiovascular therapy.Int J Pharm. 2019 Jul 20;566:1-10. doi: 10.1016/j.ijpharm.2019.05.047. Epub 2019 May 18.
82 Is urinary excretion of plasminogen associated with development of pre-eclampsia? An observational, explorative case-control study.BMJ Open. 2019 Jun 21;9(6):e026489. doi: 10.1136/bmjopen-2018-026489.
83 Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.J Thromb Haemost. 2020 Jan;18(1):234-242. doi: 10.1111/jth.14635. Epub 2019 Oct 20.
84 Influence of PRKCH gene polymorphism on antihypertensive response to amlodipine and telmisartan.Clin Exp Hypertens. 2017;39(8):726-731. doi: 10.1080/10641963.2017.1324475. Epub 2017 Jun 22.
85 Brain Prostaglandin D2 Increases Neurogenic Pressor Activity and Mean Arterial Pressure in Angiotensin II-Salt Hypertensive Rats.Hypertension. 2019 Dec;74(6):1499-1506. doi: 10.1161/HYPERTENSIONAHA.119.13175. Epub 2019 Oct 7.
86 Activities of aminopeptidases in a rat saline model of volume hypertension.Horm Metab Res. 1998 May;30(5):246-8. doi: 10.1055/s-2007-978876.
87 Opportunities to Leverage Telehealth Approaches Along the Hypertension Control Cascade in Sub-Saharan Africa.Curr Hypertens Rep. 2019 Aug 26;21(10):75. doi: 10.1007/s11906-019-0983-2.
88 Role of uteroglobin G38A polymorphism in the progression of IgA nephropathy in Japanese patients.Kidney Int. 2002 May;61(5):1853-8. doi: 10.1046/j.1523-1755.2002.00336.x.
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115 Hypertension-causing cullin 3 mutations disrupt COP9 signalosome binding.Am J Physiol Renal Physiol. 2020 Jan 1;318(1):F204-F208. doi: 10.1152/ajprenal.00497.2019. Epub 2019 Dec 9.
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131 Antihypertensive effects of peroxisome proliferator-activated receptor- activation in spontaneously hypertensive rats.Hypertension. 2011 Oct;58(4):733-43. doi: 10.1161/HYPERTENSIONAHA.111.174490. Epub 2011 Aug 8.
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137 Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension.Circ Res. 2019 Mar 15;124(6):846-855. doi: 10.1161/CIRCRESAHA.118.313356.
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144 Genome-wide scan for circulating vascular adhesion protein-1 levels: MACROD2 as a potential transcriptional regulator of adipogenesis.J Diabetes Investig. 2018 Sep;9(5):1067-1074. doi: 10.1111/jdi.12805. Epub 2018 Feb 26.
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150 Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats.Front Physiol. 2017 Apr 20;8:227. doi: 10.3389/fphys.2017.00227. eCollection 2017.
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153 A Novel Model of Mixed Vascular Dementia Incorporating Hypertension in a Rat Model of Alzheimer's Disease.Front Physiol. 2019 Oct 24;10:1269. doi: 10.3389/fphys.2019.01269. eCollection 2019.
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156 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.Nat Commun. 2018 Nov 28;9(1):5052. doi: 10.1038/s41467-018-07345-0.
157 Estimated glomerular filtration rate predicts incident stroke among Ghanaians with diabetes and hypertension.J Neurol Sci. 2019 Jan 15;396:140-147. doi: 10.1016/j.jns.2018.11.017. Epub 2018 Nov 15.
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162 Influence of serum adiponectin level and SNP +45 polymorphism of adiponectin gene on myocardial fibrosis.J Zhejiang Univ Sci B. 2013 Aug;14(8):721-8. doi: 10.1631/jzus.BQICC707.
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180 Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.Cardiovasc Res. 2018 Aug 1;114(10):1385-1399. doi: 10.1093/cvr/cvy078.
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191 Interleukin 22 Promotes Blood Pressure Elevation and Endothelial Dysfunction in Angiotensin II-Treated Mice.J Am Heart Assoc. 2017 Oct 3;6(10):e005875. doi: 10.1161/JAHA.117.005875.
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194 Association study of IGFBP1 and IGFBP3 polymorphisms with hypertension and cardio-cerebral vascular diseases in a Chinese Han population.Oncotarget. 2017 Sep 12;8(44):77836-77845. doi: 10.18632/oncotarget.20839. eCollection 2017 Sep 29.
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212 Impaired Aortic Contractility to Uridine Adenosine Tetraphosphate in Angiotensin II-Induced Hypertensive Mice: Receptor Desensitization?.Am J Hypertens. 2017 Mar 1;30(3):304-312. doi: 10.1093/ajh/hpw163.
213 BMPR2 mutations and endothelial dysfunction in pulmonary arterial hypertension (2017 Grover Conference Series).Pulm Circ. 2018 Apr-Jun;8(2):2045894018765840. doi: 10.1177/2045894018765840. Epub 2018 Mar 9.
214 The peptidylglycine--amidating monooxygenase (PAM) gene rs13175330 A>G polymorphism is associated with hypertension in a Korean population.Hum Genomics. 2017 Nov 21;11(1):29. doi: 10.1186/s40246-017-0125-3.
215 Association of platelet-derived growth factor-D gene polymorphism with ischemic stroke in a Chinese case-control study.Blood Coagul Fibrinolysis. 2008 Jul;19(5):415-9. doi: 10.1097/MBC.0b013e3283049650.
216 Protective role of AgRP neuron's PDK1 against salt-induced hypertension.Biochem Biophys Res Commun. 2018 Jun 12;500(4):910-916. doi: 10.1016/j.bbrc.2018.04.192. Epub 2018 Apr 30.
217 Association of genetic variants with hypertension in a longitudinal population-based genetic epidemiological study.Int J Mol Med. 2015 May;35(5):1189-98. doi: 10.3892/ijmm.2015.2151. Epub 2015 Mar 20.
218 Comparison of serum Lp-PLA2 levels in ischemic stroke patients with H-type hypertension or non-H-type hypertension.J Clin Lab Anal. 2020 Feb;34(2):e23068. doi: 10.1002/jcla.23068. Epub 2019 Oct 19.
219 PLC1-PKC-IP(3)R1 signaling plays an important role in hypoxia-induced calcium response in pulmonary artery smooth muscle cells.Am J Physiol Lung Cell Mol Physiol. 2018 May 1;314(5):L724-L735. doi: 10.1152/ajplung.00243.2017. Epub 2018 Feb 1.
220 Phospholipase D2 loss results in increased blood pressure via inhibition of the endothelial nitric oxide synthase pathway.Sci Rep. 2017 Aug 22;7(1):9112. doi: 10.1038/s41598-017-09852-4.
221 Polymorphisms in PLIN and hypertension combined with obesity and lipid profiles in Han Chinese.Obes Res. 2004 Nov;12(11):1733-7. doi: 10.1038/oby.2004.214.
222 Identifying multiple causative genes at a single GWAS locus.Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.
223 PPAR is a gatekeeper for extracellular matrix and vascular cell homeostasis: beneficial role in pulmonary hypertension and renal/cardiac/pulmonary fibrosis.Curr Opin Nephrol Hypertens. 2020 Mar;29(2):171-179. doi: 10.1097/MNH.0000000000000580.
224 Lower cardiovagal tone and baroreflex sensitivity associated with hepatic insulin resistance and promote cardiovascular disorders in Tibetan minipigs induced by a high fat and high cholesterol diet.J Diabetes Complications. 2019 Apr;33(4):278-288. doi: 10.1016/j.jdiacomp.2018.12.014. Epub 2019 Jan 4.
225 Analysis of Genes Related to Angiotensin II-Induced Arterial Injury Using a Time Series Microarray.Cell Physiol Biochem. 2018;48(3):983-992. doi: 10.1159/000491966. Epub 2018 Jul 23.
226 Severe polycystic liver diseases: hepatectomy or waiting for liver transplantation?: Two case reports.Medicine (Baltimore). 2019 Dec;98(49):e18176. doi: 10.1097/MD.0000000000018176.
227 Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates A-40 levels to presenilin 2.Hum Genet. 2012 Dec;131(12):1869-76. doi: 10.1007/s00439-012-1210-2. Epub 2012 Aug 8.
228 Comparative evaluation of CacyBP/SIP protein, -catenin, and immunoproteasome subunit LMP7 in the heart of rats with hypertension of different etiology.Exp Biol Med (Maywood). 2018 Nov;243(15-16):1199-1206. doi: 10.1177/1535370218815435. Epub 2018 Nov 24.
229 Dysregulation of microRNA-214 and PTEN contributes to the pathogenesis of hypoxic pulmonary hypertension.Int J Chron Obstruct Pulmon Dis. 2017 Jun 19;12:1781-1791. doi: 10.2147/COPD.S104627. eCollection 2017.
230 Inhibition of CRTH2-mediated Th2 activation attenuates pulmonary hypertension in mice.J Exp Med. 2018 Aug 6;215(8):2175-2195. doi: 10.1084/jem.20171767. Epub 2018 Jul 3.
231 Dual-targeting Rutaecarpine-NO donor hybrids as novel anti-hypertensive agents by promoting release of CGRP.Eur J Med Chem. 2019 Apr 15;168:146-153. doi: 10.1016/j.ejmech.2019.02.037. Epub 2019 Feb 18.
232 Apparent mineralocorticoid excess syndrome: an overview.Arq Bras Endocrinol Metabol. 2004 Oct;48(5):687-96. doi: 10.1590/s0004-27302004000500015. Epub 2005 Mar 7.
233 Genetic variations in sterol regulatory element binding protein cleavage-activating protein (SCAP) are associated with blood pressure in overweight/obese Chinese children.PLoS One. 2017 May 19;12(5):e0177973. doi: 10.1371/journal.pone.0177973. eCollection 2017.
234 Acute salt loading induces sympathetic nervous system overdrive in mice lacking salt-inducible kinase 1 (SIK1).Hypertens Res. 2019 Aug;42(8):1114-1124. doi: 10.1038/s41440-019-0249-z. Epub 2019 Mar 20.
235 Modulation of Sympathetic Overactivity to Treat Resistant Hypertension.Curr Hypertens Rep. 2018 Sep 7;20(11):92. doi: 10.1007/s11906-018-0893-8.
236 Associations of Endothelial System Genes With Blood Pressure Changes and Hypertension Incidence: The GenSalt Study.Am J Hypertens. 2015 Jun;28(6):780-8. doi: 10.1093/ajh/hpu223. Epub 2014 Nov 25.
237 Hypoxia Triggers SENP1 (Sentrin-Specific Protease 1) Modulation of KLF15 (Kruppel-Like Factor 15) and Transcriptional Regulation of Arg2 (Arginase 2) in Pulmonary Endothelium.Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):913-926. doi: 10.1161/ATVBAHA.117.310660. Epub 2018 Feb 22.
238 Joint Association of Obesity and Hypertension with Disability in the Elderly-- A Community-Based Study of Residents in Shanghai, China.J Nutr Health Aging. 2017;21(4):362-369. doi: 10.1007/s12603-016-0777-z.
239 The chloride channel/transporter Slc26a9 regulates the systemic arterial pressure and renal chloride excretion.J Mol Med (Berl). 2013 May;91(5):561-72. doi: 10.1007/s00109-012-0973-1. Epub 2012 Nov 13.
240 A polymorphism in the major gene regulating serum uric acid associates with clinic SBP and the white-coat effect in a family-based study.J Hypertens. 2014 Aug;32(8):1621-8; discussion 1628. doi: 10.1097/HJH.0000000000000224.
241 Vesicle miR-195 derived from Endothelial Cells Inhibits Expression of Serotonin Transporter in Vessel Smooth Muscle Cells.Sci Rep. 2017 Mar 8;7:43546. doi: 10.1038/srep43546.
242 miRNA-145 is associated with spontaneous hypertension by targeting SLC7A1.Exp Ther Med. 2018 Jan;15(1):548-552. doi: 10.3892/etm.2017.5371. Epub 2017 Oct 24.
243 Influence of Long-Term Salt Diets on Cardiac Ca2+ Handling and Contractility Proteins in Hypertensive Rats.Am J Hypertens. 2018 May 7;31(6):726-734. doi: 10.1093/ajh/hpy023.
244 MST3 (mammalian Ste20-like protein kinase 3), a novel gene involved in ion homeostasis and renal regulation of blood pressure in spontaneous hypertensive rats.Int Urol Nephrol. 2018 Dec;50(12):2299-2307. doi: 10.1007/s11255-018-2011-x. Epub 2018 Oct 16.
245 Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39.Sci Rep. 2016 Jun 21;6:28210. doi: 10.1038/srep28210.
246 Regulation of Cardiac Mast Cell Maturation and Function by the Neurokinin-1 Receptor in the Fibrotic Heart.Sci Rep. 2019 Jul 29;9(1):11004. doi: 10.1038/s41598-019-47369-0.
247 Transgelin as a therapeutic target to prevent hypoxic pulmonary hypertension.Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15;306(6):L574-83. doi: 10.1152/ajplung.00327.2013. Epub 2014 Jan 24.
248 Antagonist of thromboxane A2 receptor by SQ29548 lowers DOCA-induced hypertension in diabetic rats.Eur J Pharmacol. 2017 Nov 15;815:298-303. doi: 10.1016/j.ejphar.2017.09.028. Epub 2017 Sep 20.
249 The activation of the kynurenine pathway in a rat model with renovascular hypertension.Exp Biol Med (Maywood). 2017 Apr;242(7):750-761. doi: 10.1177/1535370217693114. Epub 2017 Jan 1.
250 Blood pressure homeostasis is maintained by a P311-TGF- axis.J Clin Invest. 2013 Oct;123(10):4502-12. doi: 10.1172/JCI69884. Epub 2013 Sep 16.
251 Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.Immunity. 2013 Apr 18;38(4):754-68. doi: 10.1016/j.immuni.2013.02.009. Epub 2013 Mar 7.
252 Sex differences in platelet toll-like receptors and their association with cardiovascular risk factors.Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):1030-7. doi: 10.1161/ATVBAHA.114.304954. Epub 2015 Feb 5.
253 Association of gene polymorphisms in RANKL/RANK/OPG system with hypertension and blood pressure in Chinese women.J Hum Hypertens. 2015 Dec;29(12):749-53. doi: 10.1038/jhh.2015.13. Epub 2015 Mar 26.
254 Tryptophan hydroxylase 1 Inhibition Impacts Pulmonary Vascular Remodeling in Two Rat Models of Pulmonary Hypertension.J Pharmacol Exp Ther. 2017 Feb;360(2):267-279. doi: 10.1124/jpet.116.237933. Epub 2016 Dec 7.
255 Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.J Biol Chem. 2018 Oct 12;293(41):16102-16114. doi: 10.1074/jbc.RA118.005066. Epub 2018 Aug 23.
256 Voltage-dependent anion channel-2 interaction with nitric oxide synthase enhances pulmonary artery endothelial cell nitric oxide production.Am J Respir Cell Mol Biol. 2012 Nov;47(5):669-78. doi: 10.1165/rcmb.2011-0436OC. Epub 2012 Jul 27.
257 Knockout of mitochondrial voltage-dependent anion channel type 3 increases reactive oxygen species (ROS) levels and alters renal sodium transport.J Biol Chem. 2018 Feb 2;293(5):1666-1675. doi: 10.1074/jbc.M117.798645. Epub 2017 Nov 27.
258 Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review.Sao Paulo Med J. 2012;130(1):57-60. doi: 10.1590/s1516-31802012000100010.
259 VIP Regulates Morphology and F-Actin Distribution of Schlemm's Canal in a Chronic Intraocular Pressure Hypertension Model via the VPAC2 Receptor.Invest Ophthalmol Vis Sci. 2018 Jun 1;59(7):2848-2860. doi: 10.1167/iovs.17-22688.
260 Lovastatin attenuates hypertension induced by renal tubule-specific knockout of ATP-binding cassette transporter A1, by inhibiting epithelial sodium channels.Br J Pharmacol. 2019 Sep;176(18):3695-3711. doi: 10.1111/bph.14775. Epub 2019 Jul 30.
261 Allele-specific polymerase chain reaction for the detection of single nucleotide polymorphism in amlodipine-induced gingival enlargement.J Clin Pharm Ther. 2018 Feb;43(1):110-113. doi: 10.1111/jcpt.12587. Epub 2017 Jun 27.
262 Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):762-8. doi: 10.1161/01.ATV.0000259298.11129.a2. Epub 2007 Feb 1.
263 Inhibition of MRP4 prevents and reverses pulmonary hypertension in mice.J Clin Invest. 2011 Jul;121(7):2888-97. doi: 10.1172/JCI45023. Epub 2011 Jun 13.
264 Decreased expression of aortic KIR6.1 and SUR2B in hypertension does not correlate with changes in the functional role of K(ATP) channels.Eur J Pharmacol. 2008 Jun 10;587(1-3):204-8. doi: 10.1016/j.ejphar.2008.03.039. Epub 2008 Mar 30.
265 Differential regulation of (2)-adrenoceptor and adenosine A(2B) receptor signalling by GRK and arrestin proteins in arterial smooth muscle.Cell Signal. 2018 Nov;51:86-98. doi: 10.1016/j.cellsig.2018.07.013. Epub 2018 Jul 31.
266 Everyday Racial Discrimination and Hypertension among Midlife African American Women: Disentangling the Role of Active Coping Dispositions versus Active Coping Behaviors.Int J Environ Res Public Health. 2019 Nov 27;16(23):4759. doi: 10.3390/ijerph16234759.
267 Smoking and hypertension: Effect of adenosine deaminase polymorphism.Clin Exp Hypertens. 2019;41(6):548-551. doi: 10.1080/10641963.2018.1516776. Epub 2018 Sep 7.
268 The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.Eur Respir J. 2019 Mar 28;53(3):1801805. doi: 10.1183/13993003.01805-2018. Print 2019 Mar.
269 PACAP-(6-38) or kynurenate microinjections in the RVLM prevent the development of sympathetic long-term facilitation after acute intermittent hypoxia.Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H563-H572. doi: 10.1152/ajpheart.00596.2017. Epub 2017 Dec 6.
270 Expression of vasoactive intestinal peptide and related receptors in overcirculation-induced pulmonary hypertension in piglets.Pediatr Res. 2009 Oct;66(4):395-9. doi: 10.1203/PDR.0b013e3181b33804.
271 Identification of 13 novel susceptibility loci for early-onset myocardial infarction, hypertension, or chronic kidney disease.Int J Mol Med. 2018 Nov;42(5):2415-2436. doi: 10.3892/ijmm.2018.3852. Epub 2018 Sep 4.
272 Synergistic interaction between a PDE5 inhibitor (sildenafil) and a new adenosine A2A receptor agonist (LASSBio-1359) improves pulmonary hypertension in rats.PLoS One. 2018 Apr 20;13(4):e0195047. doi: 10.1371/journal.pone.0195047. eCollection 2018.
273 Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension.Front Physiol. 2018 Jun 1;9:555. doi: 10.3389/fphys.2018.00555. eCollection 2018.
274 Vaccine Targeted Alpha 1D-Adrenergic Receptor for Hypertension.Hypertension. 2019 Dec;74(6):1551-1562. doi: 10.1161/HYPERTENSIONAHA.119.13700. Epub 2019 Oct 14.
275 Alpha2B-Adrenergic Receptor Overexpression in the Brain Potentiate Air Pollution-induced Behavior and Blood Pressure Changes.Toxicol Sci. 2019 May 1;169(1):95-107. doi: 10.1093/toxsci/kfz025.
276 Association between common genetic variants of 2A-, 2B- and 2C-adrenoceptors and the risk of silent brain infarction.Mol Med Rep. 2014 Jun;9(6):2459-66. doi: 10.3892/mmr.2014.2072. Epub 2014 Mar 27.
277 The Association of ADRB1 and CYP2D6 Polymorphisms With Antihypertensive Effects and Analysis of Their Contribution to Hypertension Risk.Am J Med Sci. 2018 Mar;355(3):235-239. doi: 10.1016/j.amjms.2017.11.002. Epub 2017 Nov 13.
278 The mutation of Trp64Arg in 3-adrenoreceptor-encoding gene is significantly associated with increased hypertension risk and elevated blood pressure: a meta-analysis.Oncotarget. 2017 Jul 11;8(28):46480-46490. doi: 10.18632/oncotarget.16666.
279 Integrating hypertension screening at the time of voluntary HIV testing among adults in South Africa.PLoS One. 2019 Feb 8;14(2):e0210161. doi: 10.1371/journal.pone.0210161. eCollection 2019.
280 Rosiglitazone, a Ligand to PPAR, Improves Blood Pressure and Vascular Function through Renin-Angiotensin System Regulation.PPAR Res. 2019 Feb 3;2019:1371758. doi: 10.1155/2019/1371758. eCollection 2019.
281 Transgenic mice with -6A haplotype of the human angiotensinogen gene have increased blood pressure compared with -6G haplotype.J Biol Chem. 2010 Dec 24;285(52):41172-86. doi: 10.1074/jbc.M110.167585. Epub 2010 Oct 26.
282 Maternal Exposure to Bisphenol A Combined with High-Fat Diet-Induced Programmed Hypertension in Adult Male Rat Offspring: Effects of Resveratrol.Int J Mol Sci. 2019 Sep 6;20(18):4382. doi: 10.3390/ijms20184382.
283 Deletion of protein kinase B2 preserves cardiac function by blocking interleukin-6-mediated injury and restores blood pressure during angiotensin II/high-salt-diet-induced hypertension.J Hypertens. 2018 Apr;36(4):834-846. doi: 10.1097/HJH.0000000000001613.
284 ALDH2 rs671 polymorphism and the risk of heart failure with preserved ejection fraction (HFpEF) in patients with cardiovascular diseases.J Hum Hypertens. 2020 Jan;34(1):16-23. doi: 10.1038/s41371-019-0182-2. Epub 2019 Mar 7.
285 An aldosterone-related system in the ventrolateral medulla oblongata of spontaneously hypertensive and Wistar-Kyoto rats.Clin Exp Pharmacol Physiol. 2006 Jan-Feb;33(1-2):71-5. doi: 10.1111/j.1440-1681.2006.04326.x.
286 Pharmacological properties of marine macroalgae-associated heterotrophic bacteria.Arch Microbiol. 2019 May;201(4):505-518. doi: 10.1007/s00203-018-1592-1. Epub 2018 Nov 7.
287 Effect of race, genetic population structure, and genetic models in two-locus association studies: clustering of functional renin-angiotensin system gene variants in hypertension association studies.Braz J Med Biol Res. 2001 Nov;34(11):1421-8. doi: 10.1590/s0100-879x2001001100008.
288 Genome-wide gene expression array identifies novel genes related to disease severity and excessive daytime sleepiness in patients with obstructive sleep apnea.PLoS One. 2017 May 17;12(5):e0176575. doi: 10.1371/journal.pone.0176575. eCollection 2017.
289 Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension.Lipids Health Dis. 2018 Mar 1;17(1):35. doi: 10.1186/s12944-018-0681-0.
290 Endophilin A2 regulates calcium-activated chloride channel activity via selective autophagy-mediated TMEM16A degradation.Acta Pharmacol Sin. 2020 Feb;41(2):208-217. doi: 10.1038/s41401-019-0298-5. Epub 2019 Sep 4.
291 Combinatorial inhibition of Angiotensin converting enzyme, Neutral endopeptidase and Aminopeptidase N by N-methylated peptides alleviates blood pressure and fibrosis in rat model of dexamethasone-induced hypertension.Peptides. 2020 Jan;123:170180. doi: 10.1016/j.peptides.2019.170180. Epub 2019 Nov 10.
292 Validation of the Beneware model ABP-021 ambulatory blood pressure monitor according to the revised 2010 European Society of hypertension international protocol.Blood Press Monit. 2018 Aug;23(4):210-213. doi: 10.1097/MBP.0000000000000330.
293 Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer's disease.Acta Neuropathol Commun. 2018 Jun 4;6(1):46. doi: 10.1186/s40478-018-0540-2.
294 Management and long-term outcomes of sarcoidosis-associated pulmonary hypertension.Eur Respir J. 2017 Oct 19;50(4):1700465. doi: 10.1183/13993003.00465-2017. Print 2017 Oct.
295 ApoA-IV polymorphism associated with myocardial infarction in obese NIDDM patients. The San Luis Valley Diabetes Study.Diabetes. 1994 Dec;43(12):1485-9. doi: 10.2337/diab.43.12.1485.
296 The Impact of APOL1 on Chronic Kidney Disease and Hypertension.Adv Chronic Kidney Dis. 2019 Mar;26(2):131-136. doi: 10.1053/j.ackd.2019.01.003.
297 Blood-Brain Barrier Disruption and Perivascular Beta-Amyloid Accumulation in the Brain of Aged Rats with Spontaneous Hypertension: Evaluation with Dynamic Contrast-Enhanced Magnetic Resonance Imaging.Korean J Radiol. 2018 May-Jun;19(3):498-507. doi: 10.3348/kjr.2018.19.3.498. Epub 2018 Apr 6.
298 Aqp-1 Gene Knockout Attenuates Hypoxic Pulmonary Hypertension of Mice.Arterioscler Thromb Vasc Biol. 2019 Jan;39(1):48-62. doi: 10.1161/ATVBAHA.118.311714.
299 Androgen Receptor Blockade Differentially Regulates Blood Pressure in Growth-Restricted Versus Ovarian Deficient Rats.Hypertension. 2019 Oct;74(4):975-982. doi: 10.1161/HYPERTENSIONAHA.119.13257. Epub 2019 Aug 5.
300 Plasmatic Concentrations of ADMA and Homocystein in Llama (Lama glama) and Regulation of Arginase Type II: An Animal Resistent to the Development of Pulmonary Hypertension Induced by Hypoxia.Front Physiol. 2018 May 29;9:606. doi: 10.3389/fphys.2018.00606. eCollection 2018.
301 Vascular Endothelial Growth Factor Receptor 3 Regulates Endothelial Function Through -Arrestin 1.Circulation. 2019 Mar 26;139(13):1629-1642. doi: 10.1161/CIRCULATIONAHA.118.034961.
302 A functional 12T-insertion polymorphism in the ATP1A1 promoter confers decreased susceptibility to hypertension in a male Sardinian population.PLoS One. 2015 Jan 23;10(1):e0116724. doi: 10.1371/journal.pone.0116724. eCollection 2015.
303 Inactivation of Cys(674) in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase.Br J Pharmacol. 2020 Apr;177(8):1793-1805. doi: 10.1111/bph.14937. Epub 2020 Jan 30.
304 Exacerbated pressor and sympathoexcitatory effects of central Elabela in spontaneously hypertensive rats.Am J Physiol Heart Circ Physiol. 2020 Jan 1;318(1):H124-H134. doi: 10.1152/ajpheart.00449.2019. Epub 2019 Dec 13.
305 Correlation between miRNA target site polymorphisms in the 3' UTR of AVPR1A and the risk of hypertension in the Chinese Han population.Biosci Rep. 2019 May 14;39(5):BSR20182232. doi: 10.1042/BSR20182232. Print 2019 May 31.
306 Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.Exp Ther Med. 2018 Jan;15(1):924-932. doi: 10.3892/etm.2017.5442. Epub 2017 Nov 6.
307 Upregulation of SRF Is Associated With Hypoxic Pulmonary Hypertension by Promoting Viability of Smooth Muscle Cells via Increasing Expression of Bcl-2.J Cell Biochem. 2017 Sep;118(9):2731-2738. doi: 10.1002/jcb.25922. Epub 2017 Apr 25.
308 The Effects of Bradykinin B1 Receptor Antagonism on the Myocardial and Vascular Consequences of Hypertension in SHR Rats.Front Physiol. 2019 May 21;10:624. doi: 10.3389/fphys.2019.00624. eCollection 2019.
309 Risk of bradykinin B2 receptor -58T/C gene polymorphism on hypertension: A meta-analysis.Nephrology (Carlton). 2016 Aug;21(8):655-62. doi: 10.1111/nep.12782.
310 Chemerin stimulates aortic smooth muscle cell proliferation and migration via activation of autophagy in VSMCs of metabolic hypertension rats.Am J Transl Res. 2019 Mar 15;11(3):1327-1342. eCollection 2019.
311 Genetic variation in bone morphogenetic proteins family members (BMPs 2 and 4) and hypertension risk in middle-aged men: The TAMRISK study.Medicine (Baltimore). 2017 Dec;96(51):e9362. doi: 10.1097/MD.0000000000009362.
312 Complement 5a Receptor deficiency does not influence adverse cardiac remodeling after pressure-overload in mice.Sci Rep. 2017 Dec 6;7(1):17045. doi: 10.1038/s41598-017-16957-3.
313 Hypoxia-induced Pulmonary Hypertension in Different Mouse Strains: Relation to Transcriptome.Am J Respir Cell Mol Biol. 2019 Jan;60(1):106-116. doi: 10.1165/rcmb.2017-0435OC.
314 Matrix metalloproteinase 9 gene haplotypes affect left ventricular hypertrophy in hypertensive patients.Clin Chim Acta. 2010 Dec 14;411(23-24):1940-4. doi: 10.1016/j.cca.2010.08.008. Epub 2010 Aug 11.
315 CR1 genotype and haplotype involvement in coronary artery disease: the pivotal role of hypertension and dyslipidemia.Int J Mol Med. 2009 Aug;24(2):181-7. doi: 10.3892/ijmm_00000221.
316 Associations of Variants in the CACNA1A and CACNA1C Genes With Longitudinal Blood Pressure Changes and Hypertension Incidence: The GenSalt Study.Am J Hypertens. 2016 Nov 1;29(11):1301-1306. doi: 10.1093/ajh/hpw070.
317 CACNA1H(M1549V) Mutant Calcium Channel Causes Autonomous Aldosterone Production in HAC15 Cells and Is Inhibited by Mibefradil.Endocrinology. 2016 Aug;157(8):3016-22. doi: 10.1210/en.2016-1170. Epub 2016 Jun 3.
318 Transcriptional upregulation of 2-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension.Hypertension. 2012 Oct;60(4):1006-15. doi: 10.1161/HYPERTENSIONAHA.112.199661. Epub 2012 Sep 4.
319 Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats.Life Sci. 2020 Mar 1;244:117153. doi: 10.1016/j.lfs.2019.117153. Epub 2019 Dec 10.
320 Correlation of cardiomyocyte apoptosis with duration of hypertension, severity of hypertension and caspase-3 expression in hypertensive rats.Exp Ther Med. 2019 Apr;17(4):2741-2745. doi: 10.3892/etm.2019.7249. Epub 2019 Feb 7.
321 NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs.Mediators Inflamm. 2019 Feb 13;2019:6847087. doi: 10.1155/2019/6847087. eCollection 2019.
322 Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature.Pulm Circ. 2019 Jan-Mar;9(1):2045894019837876. doi: 10.1177/2045894019837876.
323 Chemoattraction and Recruitment of Activated Immune Cells, Central Autonomic Control, and Blood Pressure Regulation.Front Physiol. 2019 Aug 2;10:984. doi: 10.3389/fphys.2019.00984. eCollection 2019.
324 The influence of familial factors on the progression of IgA nephropathy.Nephrol Dial Transplant. 1997 Sep;12(9):1963-7. doi: 10.1093/ndt/12.9.1963.
325 CCR2/CCR5-mediated macrophage-smooth muscle cell crosstalk in pulmonary hypertension.Eur Respir J. 2019 Oct 10;54(4):1802308. doi: 10.1183/13993003.02308-2018. Print 2019 Oct.
326 Cluster of differentiation 36 gene polymorphism (rs1761667) is associated with dietary MUFA intake and hypertension in a Japanese population.Br J Nutr. 2019 Jun;121(11):1215-1222. doi: 10.1017/S0007114519000679. Epub 2019 Mar 29.
327 Sample size re-estimation in crossover trials: application to the AIM HY-INFORM study.Trials. 2019 Dec 2;20(1):665. doi: 10.1186/s13063-019-3724-6.
328 Evaluation of 12 Novel Molecular Markers for Degenerated Nucleus Pulposus in a Chinese Population.Spine (Phila Pa 1976). 2015 Aug 15;40(16):1252-60. doi: 10.1097/BRS.0000000000000929.
329 Involvement of S100A4/Mts1 and associated proteins in the protective effect of fluoxetine against MCT - Induced pulmonary hypertension in rats.J Chin Med Assoc. 2018 Dec;81(12):1077-1087. doi: 10.1016/j.jcma.2018.03.013. Epub 2018 Jul 19.
330 Evacetrapib: Another CETP Inhibitor for Dyslipidemia With No Clinical Benefit.Cardiol Rev. 2017 Mar/Apr;25(2):43-52. doi: 10.1097/CRD.0000000000000137.
331 Complement alternative pathway activation associated with pulmonary hypertension in lupus nephritis patients.Lupus. 2019 Aug;28(9):1051-1061. doi: 10.1177/0961203319860192. Epub 2019 Jul 11.
332 The ClC-3 chloride channels in cardiovascular disease.Acta Pharmacol Sin. 2011 Jun;32(6):675-84. doi: 10.1038/aps.2011.30. Epub 2011 May 23.
333 Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk.Circ Cardiovasc Genet. 2016 Feb;9(1):64-70. doi: 10.1161/CIRCGENETICS.115.001215. Epub 2015 Dec 11.
334 T-HOD: a literature-based candidate gene database for hypertension, obesity and diabetes.Database (Oxford). 2013 Feb 12;2013:bas061. doi: 10.1093/database/bas061. Print 2013.
335 Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT(1) receptor blockers valsartan and olmesartan.Br J Pharmacol. 2017 Jul;174(13):1972-1983. doi: 10.1111/bph.13794. Epub 2017 Apr 26.
336 Effects of the selective chymase inhibitor TEI-F00806 on the intrarenal renin-angiotensin system in salt-treated angiotensin I-infused hypertensive mice.Exp Physiol. 2018 Nov;103(11):1524-1531. doi: 10.1113/EP087209. Epub 2018 Sep 14.
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338 Role of cannabinoid receptor type 1 in rostral ventrolateral medulla in high-fat diet-induced hypertension in rats.J Hypertens. 2018 Apr;36(4):801-808. doi: 10.1097/HJH.0000000000001621.
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348 The chemokine receptor CX(3)CR1 reduces renal injury in mice with angiotensin II-induced hypertension.Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1526-F1535. doi: 10.1152/ajprenal.00149.2018. Epub 2018 Sep 12.
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351 Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension.Eur Respir J. 2019 Jun 13;53(6):1801524. doi: 10.1183/13993003.01524-2018. Print 2019 Jun.
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363 Polymorphisms of ECE1 may contribute to susceptibility to ischemic stroke in Han Chinese of Northern China.Cell Biochem Biophys. 2014 Jun;69(2):237-46. doi: 10.1007/s12013-013-9789-z.
364 Selective ETA vs. dual ETA/B receptor blockade for the prevention of sunitinib-induced hypertension and albuminuria in WKY rats.Cardiovasc Res. 2020 Aug 1;116(10):1779-1790. doi: 10.1093/cvr/cvz260.
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366 Unique wreath-like smooth muscle proliferation of the pulmonary vasculature in pulmonary veno-occlusive disease versus pulmonary arterial hypertension.J Formos Med Assoc. 2020 Jan;119(1 Pt 2):300-309. doi: 10.1016/j.jfma.2019.05.019. Epub 2019 Jun 13.
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373 EPHA6 rs4857055 C?T polymorphism associates with hypertension through triglyceride and LDL particle size in the Korean population.Lipids Health Dis. 2017 Dec 6;16(1):230. doi: 10.1186/s12944-017-0620-5.
374 EPHB6 controls catecholamine biosynthesis by up-regulating tyrosine hydroxylase transcription in adrenal gland chromaffin cells.J Biol Chem. 2019 Apr 26;294(17):6871-6887. doi: 10.1074/jbc.RA118.005767. Epub 2019 Mar 1.
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418 The relation of blood pressure and carotid intima-media thickness with the glutathione cycle in a young bi-ethnic population: the African-PREDICT study.J Hum Hypertens. 2018 Apr;32(4):268-277. doi: 10.1038/s41371-018-0044-3. Epub 2018 Mar 12.
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462 JNK2 regulates vascular remodeling in pulmonary hypertension.Pulm Circ. 2018 Jul-Sep;8(3):2045894018778156. doi: 10.1177/2045894018778156. Epub 2018 May 2.
463 Mannose-binding lectin (MBL2) polymorphisms and inflammation in hypertensive patients.Int J Immunogenet. 2011 Dec;38(6):525-7. doi: 10.1111/j.1744-313X.2011.01036.x. Epub 2011 Sep 6.
464 A clinical and proteomics approach to predict the presence of obstructive peripheral arterial disease: From the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) Study.Clin Cardiol. 2018 Jul;41(7):903-909. doi: 10.1002/clc.22939. Epub 2018 Jun 14.
465 Multiple roles of macrophage migration inhibitory factor in pulmonary hypertension.Am J Physiol Lung Cell Mol Physiol. 2020 Jan 1;318(1):L1-L9. doi: 10.1152/ajplung.00234.2019. Epub 2019 Oct 2.
466 Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension.Sci Transl Med. 2010 Aug 11;2(44):44ra58. doi: 10.1126/scitranslmed.3001327.
467 Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis.Arthritis Rheumatol. 2017 Nov;69(11):2209-2221. doi: 10.1002/art.40229. Epub 2017 Oct 17.
468 Association of the genetic and traditional risk factors of ischaemic heart disease with STEMI and NSTEMI development.J Renin Angiotensin Aldosterone Syst. 2017 Oct-Dec;18(4):1470320317739987. doi: 10.1177/1470320317739987.
469 A Common Tag Nucleotide Variant in MMP7 Promoter Increases Risk for Hypertension via Enhanced Interactions With CREB (Cyclic AMP Response Element-Binding Protein) Transcription Factor.Hypertension. 2019 Dec;74(6):1448-1459. doi: 10.1161/HYPERTENSIONAHA.119.12960. Epub 2019 Oct 28.
470 Curcumin attenuates migration of vascular smooth muscle cells via inhibiting NFB-mediated NLRP3 expression in spontaneously hypertensive rats.J Nutr Biochem. 2019 Oct;72:108212. doi: 10.1016/j.jnutbio.2019.07.003. Epub 2019 Jul 8.
471 Regulation of YAP by Mammalian Target of Rapamycin Complex 1 in Endothelial Cells Controls Blood Pressure Through COX-2/mPGES-1/PGE(2) Cascade.Hypertension. 2019 Oct;74(4):936-946. doi: 10.1161/HYPERTENSIONAHA.119.12834. Epub 2019 Aug 5.
472 TLR4/MyD88/NF-B signaling and PPAR- within the paraventricular nucleus are involved in the effects of telmisartan in hypertension.Toxicol Appl Pharmacol. 2016 Aug 15;305:93-102. doi: 10.1016/j.taap.2016.06.014. Epub 2016 Jun 9.
473 Expression of smooth muscle myosin heavy chain B in cardiac vessels of normotensive and hypertensive rats.Circ Res. 1998 Jul 27;83(2):204-9. doi: 10.1161/01.res.83.2.204.
474 Quercetin-Induced AMP-Activated Protein Kinase Activation Attenuates Vasoconstriction Through LKB1-AMPK Signaling Pathway.J Med Food. 2018 Feb;21(2):146-153. doi: 10.1089/jmf.2017.4052. Epub 2017 Oct 16.
475 MicroRNA410 Inhibits Pulmonary Vascular Remodeling via Regulation of Nicotinamide Phosphoribosyltransferase.Sci Rep. 2019 Jul 9;9(1):9949. doi: 10.1038/s41598-019-46352-z.
476 NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension.Sci Transl Med. 2018 Jun 13;10(445):eaap7294. doi: 10.1126/scitranslmed.aap7294.
477 Endothelial cells are a source of Nestin expression in Pulmonary Arterial Hypertension.PLoS One. 2019 Mar 18;14(3):e0213890. doi: 10.1371/journal.pone.0213890. eCollection 2019.
478 Association of Genetic Variations in NRF2, NQO1, HMOX1, and MT with Severity of Coronary Artery Disease and Related Risk Factors.Cardiovasc Toxicol. 2020 Apr;20(2):176-189. doi: 10.1007/s12012-019-09544-7.
479 Imidazoline receptors in the heart: characterization, distribution, and regulation.J Cardiovasc Pharmacol. 2002 Jun;39(6):875-83. doi: 10.1097/00005344-200206000-00013.
480 Specific hypertension smartphone application to improve medication adherence in hypertension: a cluster-randomized trial.Curr Med Res Opin. 2019 Jan;35(1):167-173. doi: 10.1080/03007995.2018.1549026. Epub 2018 Dec 5.
481 Protective effect of the standardized leaf extract of Ginkgo biloba (EGb761) against hypertension-induced renal injury in rats.Clin Exp Hypertens. 2018;40(8):703-714. doi: 10.1080/10641963.2018.1425421. Epub 2018 Jan 19.
482 Nox1/4 dual inhibitor GKT137831 attenuates hypertensive cardiac remodelling associating with the inhibition of ADAM17-dependent proinflammatory cytokines-induced signalling pathways in the rats with abdominal artery constriction.Biomed Pharmacother. 2019 Jan;109:1907-1914. doi: 10.1016/j.biopha.2018.11.077. Epub 2018 Nov 26.
483 A single-nucleotide polymorphism in C-type natriuretic peptide gene may be associated with hypertension.Hypertens Res. 2002 Sep;25(5):727-30. doi: 10.1291/hypres.25.727.
484 Neuroimmune crosstalk in the pathophysiology of hypertension.Nat Rev Cardiol. 2019 Aug;16(8):476-490. doi: 10.1038/s41569-019-0178-1.
485 Neuropeptide Y(1) Receptor NPY1R discovery of naturally occurring human genetic variants governing gene expression in cella as well as pleiotropic effects on autonomic activity and blood pressure in vivo.J Am Coll Cardiol. 2009 Sep 1;54(10):944-54. doi: 10.1016/j.jacc.2009.05.035.
486 Y2 receptor gene variants reduce the risk of hypertension in obese children and adolescents.J Hypertens. 2008 Aug;26(8):1590-4. doi: 10.1097/HJH.0b013e32830413ed.
487 Do genetic defects of DNA repair relevant proteins alter susceptibility to hypertension? A case-control study in northeastern Han Chinese.Clin Chim Acta. 2015 Feb 20;441:171-5. doi: 10.1016/j.cca.2014.12.017. Epub 2014 Dec 18.
488 Liver X receptor gene polymorphisms and variable cardiovascular outcomes in patients treated with antihypertensive therapy: results from the INVEST-GENES study.Pharmacogenet Genomics. 2011 Jun;21(6):333-40. doi: 10.1097/FPC.0b013e3283452fec.
489 Improving obesity and blood pressure.Hypertens Res. 2020 Feb;43(2):79-89. doi: 10.1038/s41440-019-0348-x. Epub 2019 Oct 25.
490 Phenotype-genotype correlation in eight Chinese 17alpha-hydroxylase/17,20 lyase-deficiency patients with five novel mutations of CYP17A1 gene.J Clin Endocrinol Metab. 2006 Sep;91(9):3619-25. doi: 10.1210/jc.2005-2283. Epub 2006 Jun 13.
491 Neuregulin-1 attenuates right ventricular diastolic stiffness in experimental pulmonary hypertension.Clin Exp Pharmacol Physiol. 2019 Mar;46(3):255-265. doi: 10.1111/1440-1681.13043. Epub 2018 Dec 2.
492 LOX-1: Regulation, Signaling and Its Role in Atherosclerosis.Antioxidants (Basel). 2019 Jul 11;8(7):218. doi: 10.3390/antiox8070218.
493 Compromised mitochondrial remodeling in compensatory hypertrophied myocardium of spontaneously hypertensive rat.Cardiovasc Pathol. 2014 Mar-Apr;23(2):101-6. doi: 10.1016/j.carpath.2013.11.002. Epub 2013 Nov 14.
494 Functional Upregulation of STIM-1/Orai-1-Mediated Store-Operated Ca2+ Contributing to the Hypertension Development Elicited by Chronic EtOH Consumption.Curr Vasc Pharmacol. 2017;15(3):265-281. doi: 10.2174/1570161115666170201122750.
495 Association of ornithine transcarbamylase gene polymorphisms with hypertension and coronary artery vasomotion.Am J Hypertens. 2009 Sep;22(9):993-1000. doi: 10.1038/ajh.2009.110. Epub 2009 Jul 2.
496 The therapeutic potential of purinergic signalling.Biochem Pharmacol. 2018 May;151:157-165. doi: 10.1016/j.bcp.2017.07.016. Epub 2017 Jul 21.
497 Ambulatory blood pressure is associated with polymorphic variation in P2X receptor genes.Hypertension. 2008 Nov;52(5):980-5. doi: 10.1161/HYPERTENSIONAHA.108.113282. Epub 2008 Oct 13.
498 P2X7, a critical regulator and potential target for bone and joint diseases.J Cell Physiol. 2019 Mar;234(3):2095-2103. doi: 10.1002/jcp.27544. Epub 2018 Oct 14.
499 Platelet membrane receptor P2Y12 H1/H2 polymorphism is highly associated with cerebral infarction: a case-control study.Neuropsychiatr Dis Treat. 2018 Aug 30;14:2225-2231. doi: 10.2147/NDT.S171213. eCollection 2018.
500 miR-185/P2Y6 Axis Inhibits Angiotensin II-Induced Human Aortic Vascular Smooth Muscle Cell Proliferation.DNA Cell Biol. 2017 May;36(5):377-385. doi: 10.1089/dna.2016.3605. Epub 2017 Mar 9.
501 Minimally Invasive Aortobiilliofemoral Endarterectomy for Aortoiliac Occlusive Disease Is a Compelling Alternative to Bypass.Vasc Endovascular Surg. 2019 Feb;53(2):97-103. doi: 10.1177/1538574418807104. Epub 2018 Nov 14.
502 Common variants in PCSK1 influence blood pressure and body mass index.J Hum Hypertens. 2015 Feb;29(2):82-6. doi: 10.1038/jhh.2014.59. Epub 2014 Jul 17.
503 Discovery of Novel Phosphodiesterase-2A Inhibitors by Structure-Based Virtual Screening, Structural Optimization, and Bioassay.J Chem Inf Model. 2017 Feb 27;57(2):355-364. doi: 10.1021/acs.jcim.6b00551. Epub 2017 Jan 18.
504 Pulmonary artery smooth muscle cells from normal subjects and IPAH patients show divergent cAMP-mediated effects on TRPC expression and capacitative Ca2+ entry.Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1202-10. doi: 10.1152/ajplung.00214.2006. Epub 2006 Dec 22.
505 Ischaemic stroke in hypertensive patients is associated with variations in the PDE4D genome region.Eur J Hum Genet. 2008 Sep;16(9):1117-25. doi: 10.1038/ejhg.2008.62. Epub 2008 Apr 9.
506 Phosphodiesterase 5 inhibitors for pulmonary hypertension.Cochrane Database Syst Rev. 2019 Jan 31;1(1):CD012621. doi: 10.1002/14651858.CD012621.pub2.
507 Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.J Med Chem. 2018 Oct 11;61(19):8797-8810. doi: 10.1021/acs.jmedchem.8b00938. Epub 2018 Sep 24.
508 MicroRNA-30c contributes to the development of hypoxia pulmonary hypertension by inhibiting platelet-derived growth factor receptor expression.Int J Biochem Cell Biol. 2015 Jul;64:155-66. doi: 10.1016/j.biocel.2015.04.001. Epub 2015 Apr 13.
509 Mesenchymal Stem Cells From Adipose Tissue Do not Improve Functional Recovery After Ischemic Stroke in Hypertensive Rats.Stroke. 2020 Jan;51(1):342-346. doi: 10.1161/STROKEAHA.119.027133. Epub 2019 Nov 7.
510 Placental growth factor as an indicator of fetal growth restriction in late-onset small-for-gestational age pregnancies.Aust N Z J Obstet Gynaecol. 2019 Feb;59(1):89-95. doi: 10.1111/ajo.12831. Epub 2018 May 31.
511 Interaction of Blood Pressure Lowering and Alteplase Dose in Acute Ischemic Stroke: Results of the Enhanced Control of Hypertension and Thrombolysis Stroke Study.Cerebrovasc Dis. 2019;48(3-6):207-216. doi: 10.1159/000504745. Epub 2019 Dec 6.
512 Identification of periostin as a critical marker of progression/reversal of hypertensive nephropathy.PLoS One. 2012;7(3):e31974. doi: 10.1371/journal.pone.0031974. Epub 2012 Mar 5.
513 The endocannabinoid system in cardiovascular function: novel insights and clinical implications.Clin Auton Res. 2018 Feb;28(1):35-52. doi: 10.1007/s10286-017-0488-5. Epub 2017 Dec 8.
514 Associations between hypertension and the peroxisome proliferator-activated receptor- (PPARD) gene rs7770619 C>T polymorphism in a Korean population.Hum Genomics. 2018 Jun 18;12(1):28. doi: 10.1186/s40246-018-0162-6.
515 Elevated Serum Cyclophilin B Levels Are Associated with the Prevalence and Severity of Metabolic Syndrome.Front Endocrinol (Lausanne). 2017 Dec 22;8:360. doi: 10.3389/fendo.2017.00360. eCollection 2017.
516 Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II.J Mol Med (Berl). 2017 May;95(5):473-486. doi: 10.1007/s00109-017-1513-9. Epub 2017 Feb 3.
517 Aerobic exercise-induced inhibition of PKC/Ca(V)1.2 pathway enhances the vasodilation of mesenteric arteries in hypertension.Arch Biochem Biophys. 2019 Dec 15;678:108191. doi: 10.1016/j.abb.2019.108191. Epub 2019 Nov 13.
518 Protein Kinase C Downregulation Enhanced Extracellular Ca(2+)-Induced Relaxation of Isolated Mesenteric Arteries from Aged Dahl Salt-Sensitive Rats.J Pharmacol Exp Ther. 2019 Sep;370(3):427-435. doi: 10.1124/jpet.119.258475. Epub 2019 Jun 13.
519 TNF- elicits phenotypic and functional alterations of vascular smooth muscle cells by miR-155-5p-dependent down-regulation of cGMP-dependent kinase 1.J Biol Chem. 2018 Sep 21;293(38):14812-14822. doi: 10.1074/jbc.RA118.004220. Epub 2018 Aug 13.
520 Prostasin: a possible candidate gene for human hypertension.Am J Hypertens. 2008 Sep;21(9):1028-33. doi: 10.1038/ajh.2008.224. Epub 2008 Jun 26.
521 Maternal Protein Restriction Alters the Renal Ptger1 DNA Methylation State in SHRSP Offspring.Nutrients. 2018 Oct 5;10(10):1436. doi: 10.3390/nu10101436.
522 Complex Role for E-Prostanoid 4 Receptors in Hypertension.J Am Heart Assoc. 2019 Feb 19;8(4):e010745. doi: 10.1161/JAHA.118.010745.
523 Myeloid Cell mPges-1 Deletion Attenuates Mortality Without Affecting Remodeling After Acute Myocardial Infarction in Mice.J Pharmacol Exp Ther. 2019 Jul;370(1):18-24. doi: 10.1124/jpet.118.256057. Epub 2019 Apr 16.
524 Pulmonary and cardiorenal cyclooxygenase-1 (COX-1), -2 (COX-2), and microsomal prostaglandin E synthase-1 (mPGES-1) and -2 (mPGES-2) expression in a hypertension model.Mediators Inflamm. 2007;2007:85091. doi: 10.1155/2007/85091.
525 AAV-PGIS gene transfer improves hypoxia-induced pulmonary hypertension in mice.Biochem Biophys Res Commun. 2007 Nov 23;363(3):656-61. doi: 10.1016/j.bbrc.2007.09.039. Epub 2007 Sep 20.
526 Structure-activity relationships for the synthesis of selective cyclooxygenase 2 inhibitors: an overview (2009-2016).Medchemcomm. 2016 Dec 12;8(3):492-500. doi: 10.1039/c6md00569a. eCollection 2017 Mar 1.
527 Parathyroid Hormone and Ischemic Cerebrovascular Event.Endocr Metab Immune Disord Drug Targets. 2019;19(8):1134-1140. doi: 10.2174/1871530319666190215150410.
528 Mechanism of vasoactive peptide intermedin in vascular collagen remodeling during angiotensin II-induced hypertention.Eur Rev Med Pharmacol Sci. 2018 Sep;22(17):5652-5658. doi: 10.26355/eurrev_201809_15832.
529 Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR(-/-) mouse model of atherosclerosis.Clin Sci (Lond). 2017 Sep 28;131(20):2489-2501. doi: 10.1042/CS20171066. Print 2017 Oct 1.
530 Association of gene polymorphisms with blood pressure and the prevalence of hypertension in community-dwelling Japanese individuals.Int J Mol Med. 2007 Apr;19(4):675-83.
531 Resveratrol regulates blood pressure by enhancing AMPK signaling to downregulate a Rac1-derived NADPH oxidase in the central nervous system.J Appl Physiol (1985). 2018 Jul 1;125(1):40-48. doi: 10.1152/japplphysiol.00686.2017. Epub 2018 Mar 1.
532 BRCA1 shields vascular smooth muscle cells from oxidative stress.J Thorac Cardiovasc Surg. 2014 Jun;147(6):1946-55, 1955.e1. doi: 10.1016/j.jtcvs.2013.09.060. Epub 2013 Nov 13.
533 RLIP76 protein knockdown attenuates obesity due to a high-fat diet.J Biol Chem. 2013 Aug 9;288(32):23394-406. doi: 10.1074/jbc.M113.480194. Epub 2013 Jul 2.
534 Regulation of phospholipase C-delta1 by ARGHAP6, a GTPase-activating protein for RhoA: possible role for enhanced activity of phospholipase C in hypertension.Int J Biochem Cell Biol. 2008;40(10):2264-73. doi: 10.1016/j.biocel.2008.03.007. Epub 2008 Mar 16.
535 Development of a mouse IgA monoclonal antibody-based enzyme-linked immunosorbent sandwich assay for the analyses of RBP4.Sci Rep. 2018 Feb 7;8(1):2578. doi: 10.1038/s41598-018-20762-x.
536 A genetic variant in cytoskeleton motors amplifies susceptibility to leukoaraiosis in hypertensive smokers: gene-environmental interactions behind vascular white matter demyelinization.J Mol Neurosci. 2007;33(2):173-9. doi: 10.1007/s12031-007-0062-z.
537 Pharmacogenomics of G protein-coupled receptor signaling: insights from health and disease.Methods Mol Biol. 2008;448:77-107. doi: 10.1007/978-1-59745-205-2_6.
538 Pathophysiological effects of RhoA and Rho-associated kinase on cardiovascular system.J Hypertens. 2016 Jan;34(1):3-10. doi: 10.1097/HJH.0000000000000768.
539 Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.Am J Respir Cell Mol Biol. 2007 Sep;37(3):309-21. doi: 10.1165/rcmb.2006-0455OC. Epub 2007 May 11.
540 Common variants of ROCKs and the risk of hypertension, and stroke: Two case-control studies and a follow-up study in Chinese Han population.Biochim Biophys Acta Mol Basis Dis. 2018 Mar;1864(3):778-783. doi: 10.1016/j.bbadis.2017.12.007. Epub 2017 Dec 13.
541 Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1.Circulation. 2009 Mar 31;119(12):1643-52. doi: 10.1161/CIRCULATIONAHA.108.787440. Epub 2009 Mar 16.
542 Alpha-adducin polymorphism in hypertensives of South African ancestry.Am J Hypertens. 2000 Jun;13(6 Pt 1):719-23. doi: 10.1016/s0895-7061(00)01187-0.
543 S1PR1 (Sphingosine-1-Phosphate Receptor 1) Signaling Regulates Blood Flow and Pressure.Hypertension. 2017 Aug;70(2):426-434. doi: 10.1161/HYPERTENSIONAHA.117.09088. Epub 2017 Jun 12.
544 Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study.J Am Heart Assoc. 2019 Mar 19;8(6):e011771. doi: 10.1161/JAHA.118.011771.
545 Spontaneous Pulmonary Hypertension Associated With Systemic Sclerosis in P-Selectin Glycoprotein Ligand 1-Deficient Mice.Arthritis Rheumatol. 2020 Mar;72(3):477-487. doi: 10.1002/art.41100. Epub 2020 Jan 28.
546 SerpinC1/Antithrombin III in kidney-related diseases.Clin Sci (Lond). 2017 May 1;131(9):823-831. doi: 10.1042/CS20160669.
547 Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension.Eur Respir J. 2019 Dec 12;54(6):1900378. doi: 10.1183/13993003.00378-2019. Print 2019 Dec.
548 SGK1 activation exacerbates diet-induced obesity, metabolic syndrome and hypertension.J Endocrinol. 2020 Jan;244(1):149-162. doi: 10.1530/JOE-19-0275.
549 MicroRNA-140-5p aggravates hypertension and oxidative stress of atherosclerosis via targeting Nrf2 and Sirt2.Int J Mol Med. 2019 Feb;43(2):839-849. doi: 10.3892/ijmm.2018.3996. Epub 2018 Nov 26.
550 Endothelial SIRT6 Is Vital to Prevent Hypertension and Associated Cardiorenal Injury Through Targeting Nkx3.2-GATA5 Signaling.Circ Res. 2019 May 10;124(10):1448-1461. doi: 10.1161/CIRCRESAHA.118.314032.
551 Renal denervation and CD161a immune ablation prevent cholinergic hypertension and renal sodium retention.Am J Physiol Heart Circ Physiol. 2019 Sep 1;317(3):H517-H530. doi: 10.1152/ajpheart.00234.2019. Epub 2019 Jun 7.
552 The interplay of renal potassium and sodium handling in blood pressure regulation: critical role of the WNK-SPAK-NCC pathway.J Hum Hypertens. 2019 Jul;33(7):508-523. doi: 10.1038/s41371-019-0170-6. Epub 2019 Feb 5.
553 Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold.EMBO J. 2003 Oct 15;22(20):5422-34. doi: 10.1093/emboj/cdg519.
554 A phase II trial of the effect of perindopril on hand-foot skin reaction (HFSR) incidence and severity in patients receiving regorafenib for refractory mCRC.Cancer Chemother Pharmacol. 2019 Mar;83(3):411-417. doi: 10.1007/s00280-018-3738-x. Epub 2018 Dec 8.
555 Folate nutritional genetics and risk for hypertension in an elderly population sample.J Nutrigenet Nutrigenomics. 2009;2(1):1-8. doi: 10.1159/000160079. Epub 2008 Oct 8.
556 Urate transporter gene SLC22A12 polymorphisms associated with obesity and metabolic syndrome in Caucasians with hypertension.Kidney Blood Press Res. 2012;35(6):477-82. doi: 10.1159/000337370. Epub 2012 Jun 8.
557 Role of pendrin in the pathophysiology of aldosterone-induced hypertension. Am J Hypertens. 2019 Apr 15. pii: hpz054.
558 Physiological and pharmacological roles of vascular nucleoside transporters. J Cardiovasc Pharmacol. 2012 Jan;59(1):10-5.
559 Targeted Delivery of Sildenafil for Inhibiting Pulmonary Vascular Remodeling.Hypertension. 2019 Mar;73(3):703-711. doi: 10.1161/HYPERTENSIONAHA.118.11932.
560 Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy.Am J Physiol Renal Physiol. 2006 Jan;290(1):F205-13. doi: 10.1152/ajprenal.00237.2004. Epub 2005 Aug 9.
561 A High Fat Diet During Pregnancy and Lactation Induces Cardiac and Renal Abnormalities in GLUT4 +/- Male Mice.Kidney Blood Press Res. 2017;42(3):468-482. doi: 10.1159/000479383. Epub 2017 Jul 27.
562 Arachidonic acid cytochrome P450 4F2 in hypertension: what can we learn from a transgenic mouse model??.Kidney Int. 2009 Jun;75(12):1253-1254. doi: 10.1038/ki.2009.82.
563 Knockout of Na(+)-glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration.Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F207-F217. doi: 10.1152/ajprenal.00120.2019. Epub 2019 May 15.
564 Characterization of VNTRs Within the Entire Region of SLC6A3 and Its Association with Hypertension. DNA Cell Biol. 2017 Mar;36(3):227-236.
565 Association of SLC6A9 gene variants with human essential hypertension.J Atheroscler Thromb. 2009 Jun;16(3):201-6. doi: 10.5551/jat.e125. Epub 2009 Jun 25.
566 Silencing of sodium-hydrogen exchanger 1 attenuates the proliferation, hypertrophy, and migration of pulmonary artery smooth muscle cells via E2F1.Am J Respir Cell Mol Biol. 2011 Nov;45(5):923-30. doi: 10.1165/rcmb.2011-0032OC. Epub 2011 Mar 31.
567 Genetic and genomic evidence for an important role of the Na(+)/H(+) exchanger 3 in blood pressure regulation and angiotensin II-induced hypertension.Physiol Genomics. 2019 Apr 1;51(4):97-108. doi: 10.1152/physiolgenomics.00122.2018. Epub 2019 Mar 8.
568 Loss-of-function variants influence the human serum metabolome.Sci Adv. 2016 Aug 31;2(8):e1600800. doi: 10.1126/sciadv.1600800. eCollection 2016 Aug.
569 SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation. J Am Soc Nephrol. 2009 Dec;20(12):2546-55.
570 MiR-101a ameliorates AngII-mediated hypertensive nephropathy by blockade of TGF/Smad3 and NF-B signalling in a mouse model of hypertension.Clin Exp Pharmacol Physiol. 2019 Mar;46(3):246-254. doi: 10.1111/1440-1681.13042. Epub 2018 Nov 12.
571 Defective pulmonary vascular remodeling in Smad8 mutant mice.Hum Mol Genet. 2009 Aug 1;18(15):2791-801. doi: 10.1093/hmg/ddp214. Epub 2009 May 5.
572 Effect of Sucrose Ingestion at the End of a Critical Window that Increases Hypertension Susceptibility on Peripheral Mechanisms Regulating Blood Pressure in Rats. Role of Sirtuins 1 and 3.Nutrients. 2019 Feb 1;11(2):309. doi: 10.3390/nu11020309.
573 M235-->T polymorphism of the angiotensinogen gene predicts hypertension in the elderly.J Hypertens. 1996 Sep;14(9):1061-5. doi: 10.1097/00004872-199609000-00003.
574 Cardiovascular Effects of Pharmacological Targeting of Sphingosine Kinase 1.Hypertension. 2020 Feb;75(2):383-392. doi: 10.1161/HYPERTENSIONAHA.119.13450. Epub 2019 Dec 16.
575 Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort.Clin Endocrinol (Oxf). 2012 Mar;76(3):365-72. doi: 10.1111/j.1365-2265.2011.04175.x.
576 Common variants at somatostatin are significantly associated with hypertension incidence in smoking and drinking populations.J Am Soc Hypertens. 2018 Mar;12(3):230-237.e12. doi: 10.1016/j.jash.2017.12.009. Epub 2017 Dec 28.
577 Trends in practice and outcomes from 2011 to 2015 for surgical aortic valve replacement: an update from the German Aortic Valve Registry on 42776 patients.Eur J Cardiothorac Surg. 2018 Mar 1;53(3):552-559. doi: 10.1093/ejcts/ezx408.
578 Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells.Kidney Int. 2009 Dec;76(12):1258-67. doi: 10.1038/ki.2009.360. Epub 2009 Sep 23.
579 Sulfatase 2 mediates, partially, the expression of endothelin-1 and the additive effect of Ang II-induced endothelin-1 expression by CXCL8 in vascular smooth muscle cells from spontaneously hypertensive rats.Cytokine. 2019 Feb;114:98-105. doi: 10.1016/j.cyto.2018.11.007. Epub 2018 Nov 20.
580 SphK1/S1P mediates TGF-1-induced proliferation of pulmonary artery smooth muscle cells and its potential mechanisms.Pulm Circ. 2019 Jan-Mar;9(1):2045894018816977. doi: 10.1177/2045894018816977. Epub 2018 Nov 15.
581 1,25(OH)(2)D(3) attenuates pulmonary arterial hypertension via microRNA-204 mediated Tgfbr2/Smad signaling.Exp Cell Res. 2018 Jan 15;362(2):311-323. doi: 10.1016/j.yexcr.2017.11.032. Epub 2017 Nov 28.
582 Tissue Transglutaminase-Mediated AT1 Receptor Sensitization Underlies Pro-inflammatory Cytokine LIGHT-Induced Hypertension.Am J Hypertens. 2019 Apr 22;32(5):476-485. doi: 10.1093/ajh/hpz018.
583 Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice.Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L1150-L1164. doi: 10.1152/ajplung.00302.2018. Epub 2019 Mar 20.
584 Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes.Pharmacogenomics J. 2018 Jan;18(1):106-112. doi: 10.1038/tpj.2016.67. Epub 2016 Sep 27.
585 Thymosin 4 Deficiency Exacerbates Renal and Cardiac Injury in Angiotensin-II-Induced Hypertension.Hypertension. 2018 Jun;71(6):1133-1142. doi: 10.1161/HYPERTENSIONAHA.118.10952. Epub 2018 Apr 9.
586 Altered expression of norepinephrine transporter participate in hypertension and depression through regulated TNF- and IL-6.Clin Exp Hypertens. 2020;42(2):181-189. doi: 10.1080/10641963.2019.1601205. Epub 2019 Apr 7.
587 Osteoprotegerin and RANKL serum concentrations in neonates of mothers with early-onset pre-eclampsia: comparison with neonates of normotensive mothers.Early Hum Dev. 2019 Aug;135:1-5. doi: 10.1016/j.earlhumdev.2019.06.001. Epub 2019 Jun 6.
588 TNF receptor 1 signaling is critically involved in mediating angiotensin-II-induced cardiac fibrosis.J Mol Cell Cardiol. 2013 Apr;57:59-67. doi: 10.1016/j.yjmcc.2013.01.006. Epub 2013 Jan 18.
589 Analysis of the correlation between the neutrophil-lymphocyte ratio in peripheral blood and perioperative myocardial damage in pediatric patients with frequent ventricular premature beat.Eur Rev Med Pharmacol Sci. 2018 Mar;22(6):1752-1757. doi: 10.26355/eurrev_201803_14591.
590 Some Biological Consequences of the Inhibition of Na,K-ATPase by Translationally Controlled Tumor Protein (TCTP).Int J Mol Sci. 2018 Jun 4;19(6):1657. doi: 10.3390/ijms19061657.
591 Intravenous and Intratracheal Thyrotropin Releasing Hormone and Its Analog Taltirelin Reverse Opioid-Induced Respiratory Depression in Isoflurane Anesthetized Rats.J Pharmacol Exp Ther. 2018 Jul;366(1):105-112. doi: 10.1124/jpet.118.248377. Epub 2018 Apr 19.
592 Thyrotropin-releasing hormone receptor (TRHR) gene is associated with essential hypertension.Hypertension. 2001 Sep;38(3 Pt 2):683-7. doi: 10.1161/01.hyp.38.3.683.
593 Molecular cloning and chromosomal localization of human salt-tolerant protein.Genetica. 2000;108(3):259-62. doi: 10.1023/a:1004132919896.
594 The TRPA1 Channel in the Cardiovascular System: Promising Features and Challenges.Front Pharmacol. 2019 Oct 18;10:1253. doi: 10.3389/fphar.2019.01253. eCollection 2019.
595 Erythropoietin increases expression and function of transient receptor potential canonical 5 channels.Hypertension. 2011 Aug;58(2):317-24. doi: 10.1161/HYPERTENSIONAHA.111.173690. Epub 2011 Jun 20.
596 Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension.J Physiol. 2017 Mar 1;595(5):1497-1513. doi: 10.1113/JP273327. Epub 2016 Dec 29.
597 Crosstalk Between Vascular Redox and Calcium Signaling in Hypertension Involves TRPM2 (Transient Receptor Potential Melastatin 2) Cation Channel.Hypertension. 2020 Jan;75(1):139-149. doi: 10.1161/HYPERTENSIONAHA.119.13861. Epub 2019 Nov 18.
598 Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension.Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1103-18. doi: 10.1152/ajpheart.00903.2007. Epub 2008 Jan 11.
599 Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body.Circ Res. 2019 Nov 8;125(11):989-1002. doi: 10.1161/CIRCRESAHA.119.315338. Epub 2019 Sep 23.
600 TRPM8 channel activation triggers relaxation of pudendal artery with increased sensitivity in the hypertensive rats.Pharmacol Res. 2019 Sep;147:104329. doi: 10.1016/j.phrs.2019.104329. Epub 2019 Jul 21.
601 TRPV1 (Transient Receptor Potential Vanilloid 1) Cardiac Spinal Afferents Contribute to Hypertension in Spontaneous Hypertensive Rat.Hypertension. 2019 Oct;74(4):910-920. doi: 10.1161/HYPERTENSIONAHA.119.13285. Epub 2019 Aug 19.
602 TRPV4 channel mediates adventitial fibroblast activation and adventitial remodeling in pulmonary hypertension.Am J Physiol Lung Cell Mol Physiol. 2020 Jan 1;318(1):L135-L146. doi: 10.1152/ajplung.00084.2019. Epub 2019 Nov 6.
603 Hyperplasia in glands with hormone excess.Endocr Relat Cancer. 2016 Jan;23(1):R1-14. doi: 10.1530/ERC-15-0171. Epub 2015 Sep 25.
604 Role of Thioredoxin in Age-Related Hypertension.Curr Hypertens Rep. 2018 Feb 14;20(1):6. doi: 10.1007/s11906-018-0815-9.
605 Angiotensin-neprilysin inhibition confers renoprotection in rats with diabetes and hypertension by limiting podocyte injury.J Hypertens. 2020 Apr;38(4):755-764. doi: 10.1097/HJH.0000000000002326.
606 Association of the sirtuin and mitochondrial uncoupling protein genes with carotid plaque.PLoS One. 2011;6(11):e27157. doi: 10.1371/journal.pone.0027157. Epub 2011 Nov 7.
607 Uncoupling Protein 2 Increases Blood Pressure in DJ -1 Knockout Mice.J Am Heart Assoc. 2019 May 7;8(9):e011856. doi: 10.1161/JAHA.118.011856.
608 UCP3 Ablation Exacerbates High-Salt Induced Cardiac Hypertrophy and Cardiac Dysfunction.Cell Physiol Biochem. 2018;46(4):1683-1692. doi: 10.1159/000489244. Epub 2018 Apr 20.
609 Gene Silencing and Haploinsufficiency of Csk Increase Blood Pressure.PLoS One. 2016 Jan 11;11(1):e0146841. doi: 10.1371/journal.pone.0146841. eCollection 2016.
610 Genetic variations in the sodium balance-regulating genes ENaC, NEDD4L, NDFIP2 and USP2 influence blood pressure and hypertension.Kidney Blood Press Res. 2010;33(1):15-23. doi: 10.1159/000275706. Epub 2010 Jan 15.
611 Targeting HSP90 attenuates angiotensin II-induced adventitial remodelling via suppression of mitochondrial fission.Cardiovasc Res. 2020 Apr 1;116(5):1071-1084. doi: 10.1093/cvr/cvz194.
612 A novel urotensin II receptor antagonist, KR-36996, improved cardiac function and attenuated cardiac hypertrophy in experimental heart failure.Eur J Pharmacol. 2017 Mar 15;799:94-102. doi: 10.1016/j.ejphar.2017.02.003. Epub 2017 Feb 3.
613 A Novel and Highly Potent Urotensin II Receptor Antagonist Inhibits Urotensin II-Induced Pressure Response in Mice.J Cardiovasc Pharmacol. 2019 Jan;73(1):15-21. doi: 10.1097/FJC.0000000000000618.
614 Bioavailable IGF-1 is beneficially associated with biomarkers of endothelial function in young healthy adults: The African-PREDICT study.Growth Horm IGF Res. 2018 Aug;41:28-33. doi: 10.1016/j.ghir.2018.06.002. Epub 2018 Jun 12.
615 Expression profile of mitochondrial voltage-dependent anion channel-1 (VDAC1) influenced genes is associated with pulmonary hypertension.Korean J Physiol Pharmacol. 2017 May;21(3):353-360. doi: 10.4196/kjpp.2017.21.3.353. Epub 2017 Apr 21.
616 The association between vitamin D receptor gene polymorphism and susceptibility to hypertension: a meta-analysis.Eur Rev Med Pharmacol Sci. 2019 Oct;23(20):9066-9074. doi: 10.26355/eurrev_201910_19309.
617 VEGF-C attenuates renal damage in salt-sensitive hypertension.J Cell Physiol. 2019 Jun;234(6):9616-9630. doi: 10.1002/jcp.27648. Epub 2018 Oct 30.
618 Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension.Chronobiol Int. 2019 Aug;36(8):1072-1087. doi: 10.1080/07420528.2019.1613424. Epub 2019 May 29.
619 The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population.Pharmacogenomics J. 2020 Apr;20(2):277-284. doi: 10.1038/s41397-019-0116-y. Epub 2019 Oct 25.
620 The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension.Nat Med. 2011 Oct 2;17(10):1304-9. doi: 10.1038/nm.2497.
621 Wilms' tumor protein (-KTS) modulates renin gene transcription.Kidney Int. 2008 Aug;74(4):458-66. doi: 10.1038/ki.2008.194. Epub 2008 May 21.
622 Transcription factor Fra-2 and its emerging role in matrix deposition, proliferation and inflammation in chronic lung diseases.Cell Signal. 2019 Dec;64:109408. doi: 10.1016/j.cellsig.2019.109408. Epub 2019 Aug 29.
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624 Subclinical and clinical atherosclerosis in rheumatoid arthritis: results from the 3-year, multicentre, prospective, observational GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study.Arthritis Res Ther. 2019 Sep 3;21(1):204. doi: 10.1186/s13075-019-1975-y.
625 Treatment with nitrite prevents reactive oxygen species generation in the corpora cavernosa and restores intracavernosal pressure in hypertensive rats.Nitric Oxide. 2020 Jan 1;94:19-26. doi: 10.1016/j.niox.2019.10.006. Epub 2019 Oct 11.
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628 Reduced L-carnitine transport in aortic endothelial cells from spontaneously hypertensive rats.PLoS One. 2014 Feb 28;9(2):e90339. doi: 10.1371/journal.pone.0090339. eCollection 2014.
629 Genetic Effects on the Correlation Structure ofCVD Risk Factors: Exome-Wide Data From a Ghanaian Population.Glob Heart. 2017 Jun;12(2):133-140. doi: 10.1016/j.gheart.2017.01.013. Epub 2017 Apr 10.
630 SLC28A3 rs7853758 as a new biomarker of tacrolimus elimination and new-onset hypertension in Chinese liver transplantation patients.Biomark Med. 2017 Aug;11(8):607-618. doi: 10.2217/bmm-2017-0128. Epub 2017 Jun 16.
631 Catestatin: A Master Regulator of Cardiovascular Functions.Curr Med Chem. 2018;25(11):1352-1374. doi: 10.2174/0929867324666170425100416.
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633 PAR-2 inhibition reverses experimental pulmonary hypertension.Circ Res. 2012 Apr 27;110(9):1179-91. doi: 10.1161/CIRCRESAHA.111.257568. Epub 2012 Mar 29.
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635 Risk Factors of Neovascular Glaucoma After 25-gauge Vitrectomy for Proliferative Diabetic Retinopathy with Vitreous Hemorrhage: A Retrospective Multicenter Study.Sci Rep. 2019 Oct 16;9(1):14858. doi: 10.1038/s41598-019-51411-6.
636 Evidence of Cardiovascular Calcification and Fibrosis in Pseudoxanthoma Elasticum Mouse Models Subjected to DOCA-Salt Hypertension.Sci Rep. 2019 Nov 8;9(1):16327. doi: 10.1038/s41598-019-52808-z.
637 Upregulated copper transporters in hypoxia-induced pulmonary hypertension. PLoS One. 2014 Mar 10;9(3):e90544. doi: 10.1371/journal.pone.0090544. eCollection 2014.
638 CACNB2 is associated with aberrant RAS-MAPK signaling in hypertensive Dahl Salt-Sensitive rats.Biochem Biophys Res Commun. 2019 Jun 4;513(3):760-765. doi: 10.1016/j.bbrc.2019.03.215. Epub 2019 Apr 13.
639 A Novel Na(+)-K(+)-Cl(-) Cotransporter 1 Inhibitor STS66* Reduces Brain Damage in Mice After Ischemic Stroke.Stroke. 2019 Apr;50(4):1021-1025. doi: 10.1161/STROKEAHA.118.024287.
640 Beliefs about hypertension among primary health care workers and clients in Nigeria: A qualitative study.PLoS One. 2018 Dec 19;13(12):e0209334. doi: 10.1371/journal.pone.0209334. eCollection 2018.
641 Analysis of the 206M polymorphic variant of the SLC26A6 gene encoding a Cl- oxalate transporter in patients with primary hyperparathyroidism.Eur J Endocrinol. 2009 Feb;160(2):283-8. doi: 10.1530/EJE-08-0623. Epub 2008 Nov 24.
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644 Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension.Hypertens Res. 2006 Aug;29(8):611-9. doi: 10.1291/hypres.29.611.
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646 The Hypertension Risk Variant Rs820430 Functions as an Enhancer of SLC4A7.Am J Hypertens. 2017 Feb;30(2):202-208. doi: 10.1093/ajh/hpw127. Epub 2016 Oct 25.
647 Minisatellite polymorphisms of the SLC6A19: susceptibility in hypertension.Biochem Biophys Res Commun. 2008 Oct 3;374(4):714-9. doi: 10.1016/j.bbrc.2008.07.094. Epub 2008 Jul 29.
648 NHA2 is expressed in distal nephron and regulated by dietary sodium.J Physiol Biochem. 2017 May;73(2):199-205. doi: 10.1007/s13105-016-0539-8. Epub 2016 Dec 1.
649 GNB3 C825T and ACE I/D polymorphisms on the sodium-proton exchanger and the prevalence of essential hypertension in males.Arch Med Res. 2006 Jan;37(1):150-7. doi: 10.1016/j.arcmed.2005.05.012.
650 Association between plasma activities of semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in patients with type 1 diabetes mellitus.Diabetologia. 2005 May;48(5):1002-7. doi: 10.1007/s00125-005-1716-4. Epub 2005 Apr 14.
651 Associations of genetic polymorphisms of the vitamin D pathway with blood pressure in a Han Chinese population.Clin Exp Hypertens. 2019;41(5):460-465. doi: 10.1080/10641963.2018.1506469. Epub 2018 Sep 7.
652 CYP7A1 genotypes and haplotypes associated with hypertension in an obese Han Chinese population.Hypertens Res. 2011 Jun;34(6):722-7. doi: 10.1038/hr.2011.18. Epub 2011 Feb 24.
653 Understanding racial disparities in renal cell carcinoma incidence: estimates of population attributable risk in two US populations.Cancer Causes Control. 2020 Jan;31(1):85-93. doi: 10.1007/s10552-019-01248-1. Epub 2019 Nov 28.
654 Tongsaimai reverses the hypertension and left ventricular remolding caused by abdominal aortic constriction in rats.J Ethnopharmacol. 2020 Jan 10;246:112154. doi: 10.1016/j.jep.2019.112154. Epub 2019 Aug 12.
655 Endogenous ouabain: upregulation of steroidogenic genes in hypertensive hypothalamus but not adrenal.Circulation. 2005 Aug 30;112(9):1301-8. doi: 10.1161/CIRCULATIONAHA.105.554071. Epub 2005 Aug 22.
656 Effect of the Interaction Between Hypertension and Cerebral White Matter Changes on the Progression of Alzheimer Disease.Curr Alzheimer Res. 2018;15(14):1354-1360. doi: 10.2174/1567205015666181002141013.
657 CYP4A/CYP2C modulation of the interaction of calcium channel blockers with cyclosporine on EDHF-mediated renal vasodilations in rats.Toxicol Appl Pharmacol. 2017 Nov 1;334:110-119. doi: 10.1016/j.taap.2017.09.007. Epub 2017 Sep 9.
658 Prediction of marker genes associated with hypertension by bioinformatics analyses.Int J Mol Med. 2017 Jul;40(1):137-145. doi: 10.3892/ijmm.2017.3000. Epub 2017 May 25.
659 Associations of obesity susceptibility loci with hypertension in Chinese children.Int J Obes (Lond). 2013 Jul;37(7):926-30. doi: 10.1038/ijo.2013.37. Epub 2013 Apr 16.
660 CT perfusion in predicting the morbidity and prognosis of hypoxic-ischemic encephalopathy after off-pump coronary artery bypass grafting.Neurol Res. 2017 Jun;39(6):521-529. doi: 10.1080/01616412.2017.1315862. Epub 2017 Apr 28.
661 Female C57BL/6J mice lacking the circadian clock protein PER1 are protected from nondipping hypertension.Am J Physiol Regul Integr Comp Physiol. 2019 Jan 1;316(1):R50-R58. doi: 10.1152/ajpregu.00381.2017. Epub 2018 Nov 14.
662 The relationships between arsenic methylation and both skin lesions and hypertension caused by chronic exposure to arsenic in drinking water.Environ Toxicol Pharmacol. 2017 Jul;53:89-94. doi: 10.1016/j.etap.2017.05.009. Epub 2017 May 12.
663 Paraoxonase 1 L55M, Q192R and paraoxonase 2 S311C alleles in atherothrombosis.Mol Cell Biochem. 2013 Feb;374(1-2):233-8. doi: 10.1007/s11010-012-1525-2. Epub 2012 Dec 6.
664 A common variant of the ABO gene protects against hypertension in a Spanish population.Hypertens Res. 2012 Jun;35(6):592-6. doi: 10.1038/hr.2011.218. Epub 2012 Jan 19.
665 First-in-man study of dedicated bifurcation cobalt-chromium sirolimus-eluting stent BiOSS LIM C - three-month results.Kardiol Pol. 2018;76(2):464-470. doi: 10.5603/KP.a2017.0226. Epub 2017 Dec 1.
666 Genetic polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 and liver cirrhosis, chronic calcific pancreatitis, diabetes mellitus, and hypertension among Japanese alcoholic men.Alcohol Clin Exp Res. 2013 Aug;37(8):1391-401. doi: 10.1111/acer.12108. Epub 2013 Mar 29.
667 Nucleotide ecto-enzyme metabolic pattern and spatial distribution in calcific aortic valve disease; its relation to pathological changes and clinical presentation.Clin Res Cardiol. 2020 Feb;109(2):137-160. doi: 10.1007/s00392-019-01495-x. Epub 2019 May 29.
668 Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study.Lancet Oncol. 2018 Jan;19(1):76-86. doi: 10.1016/S1470-2045(17)30906-3. Epub 2017 Dec 14.
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672 Detrimental Effects of Testosterone Addition to Estrogen Therapy Involve Cytochrome P-450-Induced 20-HETE Synthesis in Aorta of Ovariectomized Spontaneously Hypertensive Rat (SHR), a Model of Postmenopausal Hypertension.Front Physiol. 2018 May 8;9:490. doi: 10.3389/fphys.2018.00490. eCollection 2018.
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676 MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate.Am J Clin Nutr. 2010 May;91(5):1377-86. doi: 10.3945/ajcn.2009.28923. Epub 2010 Mar 24.
677 Associations of homocysteine status and homocysteine metabolism enzyme polymorphisms with hypertension and dyslipidemia in a Chinese hypertensive population.Clin Exp Hypertens. 2020;42(1):52-60. doi: 10.1080/10641963.2019.1571599. Epub 2019 Feb 20.
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696 Attenuation of Angiotensin II-Induced Hypertension in BubR1 Low-Expression Mice Via Repression of Angiotensin II Receptor 1 Overexpression.J Am Heart Assoc. 2019 Dec 3;8(23):e011911. doi: 10.1161/JAHA.118.011911. Epub 2019 Nov 30.
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713 HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study.Hypertension. 2019 Jan;73(1):68-74. doi: 10.1161/HYPERTENSIONAHA.118.11730.
714 Hrs controls sorting of the epithelial Na+ channel between endosomal degradation and recycling pathways.J Biol Chem. 2010 Oct 1;285(40):30523-30. doi: 10.1074/jbc.M110.150755. Epub 2010 Jul 30.
715 Minor variant of rs 16827043 in the iron regulator hemojuvelin gene (HJV) contributes to hypertension: The TAMRISK study.Medicine (Baltimore). 2017 Feb;96(5):e6052. doi: 10.1097/MD.0000000000006052.
716 Tubular Deficiency of Heterogeneous Nuclear Ribonucleoprotein F Elevates Systolic Blood Pressure and Induces Glycosuria in Mice.Sci Rep. 2019 Oct 31;9(1):15765. doi: 10.1038/s41598-019-52323-1.
717 The role of lifestyle behaviour on the risk of hypertension in the SUN cohort: The hypertension preventive score.Prev Med. 2019 Jun;123:171-178. doi: 10.1016/j.ypmed.2019.03.026. Epub 2019 Mar 19.
718 Inositol monophosphatase 1 as a novel interacting partner of RAGE in pulmonary hypertension.Am J Physiol Lung Cell Mol Physiol. 2019 Mar 1;316(3):L428-L444. doi: 10.1152/ajplung.00393.2018. Epub 2019 Jan 3.
719 SHIPping out diabetes-Metformin, an old friend among new SHIP2 inhibitors.Acta Physiol (Oxf). 2020 Jan;228(1):e13349. doi: 10.1111/apha.13349. Epub 2019 Aug 12.
720 Differential expression of voltage-gated K(+) channel genes in arteries from spontaneously hypertensive and Wistar-Kyoto rats.Hypertension. 2001 May;37(5):1315-22. doi: 10.1161/01.hyp.37.5.1315.
721 Diagnosing hypertension in Indigenous Canadians (DREAM-GLOBAL): A randomized controlled trial to compare the effectiveness of short message service messaging for management of hypertension: Main results.J Clin Hypertens (Greenwich). 2019 Jan;21(1):29-36. doi: 10.1111/jch.13434. Epub 2018 Nov 26.
722 Screening of Genetic Factor in the Interaction Between Periodontitis and Metabolic Traits Using Candidate Gene Association Study (CGAS).Biochem Genet. 2019 Jun;57(3):466-474. doi: 10.1007/s10528-018-9899-9. Epub 2018 Dec 13.
723 Myotrophin-kappaB DNA interaction in the initiation process of cardiac hypertrophy.Biochim Biophys Acta. 2002 May 8;1589(3):247-60. doi: 10.1016/s0167-4889(02)00178-7.
724 Analyses of Sequence Variants in the MYOC Gene and of Single Nucleotide Polymorphisms in the NR3C1 and FKBP5 Genes in Corticosteroid-Induced Ocular Hypertension.Ophthalmic Genet. 2015;36(4):299-302. doi: 10.3109/13816810.2013.879598. Epub 2015 Aug 28.
725 Effects of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone (CS-3150), on blood pressure and urinary angiotensinogen in low-renin Dahl salt-sensitive hypertensive rats.Hypertens Res. 2019 Jun;42(6):769-778. doi: 10.1038/s41440-018-0187-1. Epub 2018 Dec 26.
726 Can Nesfatin-1 Predict Hypertension in Obese Children?.J Clin Res Pediatr Endocrinol. 2020 Mar 19;12(1):29-36. doi: 10.4274/jcrpe.galenos.2019.2019.0072. Epub 2019 Jul 24.
727 TRPP2 associates with STIM1 to regulate cerebral vasoconstriction and enhance high salt intake-induced hypertensive cerebrovascular spasm.Hypertens Res. 2019 Dec;42(12):1894-1904. doi: 10.1038/s41440-019-0324-5. Epub 2019 Sep 20.
728 Downregulation of Orexin Receptor in Hypothalamic Paraventricular Nucleus Decreases Blood Pressure in Obese Zucker Rats.J Am Heart Assoc. 2019 Jul 2;8(13):e011434. doi: 10.1161/JAHA.118.011434. Epub 2019 Jun 19.
729 'I believe high blood pressure can kill me:' using the PEN-3 Cultural Model to understand patients' perceptions of an intervention to control hypertension in Ghana.Ethn Health. 2019 Apr;24(3):257-270. doi: 10.1080/13557858.2017.1346178. Epub 2017 Jul 4.
730 Study on the Intervention Effects of Pinggan Prescription () on Spontaneously Hypertensive Rats Based on Metabonomic and Pharmacodynamic Methods.Chin J Integr Med. 2019 May;25(5):348-353. doi: 10.1007/s11655-015-2126-1. Epub 2016 Dec 27.
731 PHACTR1 gene polymorphism with the risk of coronary artery disease in Chinese Han population.Postgrad Med J. 2019 Feb;95(1120):67-71. doi: 10.1136/postgradmedj-2018-136298. Epub 2019 Feb 18.
732 Longitudinal changes in the thickness of the ganglion cell-inner plexiform layer in patients with hypertension: a 4-year prospective observational study.Acta Ophthalmol. 2020 Jun;98(4):e479-e486. doi: 10.1111/aos.14291. Epub 2019 Oct 28.
733 Comprehensive genetic testing in children with a clinical diagnosis of ARPKD identifies phenocopies.Pediatr Nephrol. 2018 Oct;33(10):1713-1721. doi: 10.1007/s00467-018-3992-5. Epub 2018 Jun 28.
734 The (G>A) rs11573191 polymorphism of PLA2G5 gene is associated with premature coronary artery disease in the Mexican Mestizo population: the genetics of atherosclerotic disease Mexican study.Biomed Res Int. 2014;2014:931361. doi: 10.1155/2014/931361. Epub 2014 May 18.
735 Aortic constriction induces hypertension and cardiac hypertrophy via (pro)renin receptor activation and the PLC? signaling pathway.Mol Med Rep. 2019 Jan;19(1):573-580. doi: 10.3892/mmr.2018.9653. Epub 2018 Nov 13.
736 MicroRNA-31 Regulates Immunosuppression in Ang II (Angiotensin II)-induced Hypertension by Targeting Ppp6C (Protein Phosphatase 6c).Hypertension. 2019 May;73(5):e14-e24. doi: 10.1161/HYPERTENSIONAHA.118.12319.
737 Incidence and risk factors of acute kidney injury in critically ill patients from a single centre in Brazil: a retrospective cohort analysis.Sci Rep. 2019 Dec 2;9(1):18141. doi: 10.1038/s41598-019-54674-1.
738 Community Health Workers Improve Linkage to Hypertension Care in WesternKenya.J Am Coll Cardiol. 2019 Oct 15;74(15):1897-1906. doi: 10.1016/j.jacc.2019.08.003. Epub 2019 Sep 2.
739 Senescence Marker Protein 30 Deficiency Exacerbates Pulmonary Hypertension in Hypoxia-Exposed Mice.Int Heart J. 2019 Nov 30;60(6):1430-1434. doi: 10.1536/ihj.19-190. Epub 2019 Nov 15.
740 Impact of radon and combinatory radon/carbon dioxide spa on pain and hypertension: Results from the explorative RAD-ON01 study.Mod Rheumatol. 2019 Jan;29(1):165-172. doi: 10.1080/14397595.2018.1442640. Epub 2018 Mar 2.
741 Predictors of hypertension awareness, treatment and control in South Africa: results from the WHO-SAGE population survey (Wave 2).J Hum Hypertens. 2019 Feb;33(2):157-166. doi: 10.1038/s41371-018-0125-3. Epub 2018 Oct 31.
742 Enhanced expression of the Epithelial Sodium Channel in neutrophils from hypertensive patients.Biochim Biophys Acta Biomembr. 2019 Feb 1;1861(2):387-402. doi: 10.1016/j.bbamem.2018.11.003. Epub 2018 Nov 10.
743 The serpin protease-nexin 1 is present in rat aortic smooth muscle cells and is upregulated in L-NAME hypertensive rats.Arterioscler Thromb Vasc Biol. 2003 Jan 1;23(1):142-7. doi: 10.1161/01.atv.0000047867.98019.2d.
744 Genetic risk factors for cerebral small-vessel disease in hypertensive patients from a genetically isolated population.J Neurol Neurosurg Psychiatry. 2011 Jan;82(1):41-4. doi: 10.1136/jnnp.2009.176362. Epub 2010 Jul 28.
745 The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo.Lab Invest. 2019 Mar;99(3):399-410. doi: 10.1038/s41374-018-0116-6. Epub 2018 Oct 5.
746 Synaptic vesicle 2C and its synaptic-related function.Clin Chim Acta. 2017 Sep;472:112-117. doi: 10.1016/j.cca.2017.07.029. Epub 2017 Jul 31.
747 Association of single nucleotide polymorphisms of MTHFR, TCN2, RNF213 with susceptibility to hypertension and blood pressure.Biosci Rep. 2019 Dec 20;39(12):BSR20191454. doi: 10.1042/BSR20191454.
748 Expression of TGF-beta1 and its receptor genes (TbetaR I, TbetaR II, and TbetaR III-betaglycan) in peripheral blood leucocytes in patients with idiopathic pulmonary arterial hypertension and Eisenmenger's syndrome.Int J Mol Med. 2008 Jan;21(1):99-107.
749 Cerebral amyloid angiopathy-related cognitive impairment: The search for a specific neuropsychological pattern.Rev Neurol (Paris). 2017 Nov;173(9):562-565. doi: 10.1016/j.neurol.2017.09.006. Epub 2017 Oct 6.
750 Nifedipine represses ion channels, transporters and Ca(2+)-binding proteins in hearts of spontaneously hypertensive rats.Toxicol Appl Pharmacol. 2006 Jun 15;213(3):224-34. doi: 10.1016/j.taap.2005.10.012. Epub 2005 Dec 15.
751 Expression of aquaporins 1 and 4 in the brain of spontaneously hypertensive rats.Brain Res. 2010 Apr 14;1325:155-63. doi: 10.1016/j.brainres.2010.02.023. Epub 2010 Feb 12.
752 Role of Rho GDP dissociation inhibitor in control of epithelial sodium channel (ENaC)-mediated sodium reabsorption.J Biol Chem. 2014 Oct 10;289(41):28651-9. doi: 10.1074/jbc.M114.558262. Epub 2014 Aug 27.
753 Angiotensin II type 1 receptor-activated caspase-3 through ras/mitogen-activated protein kinase/extracellular signal-regulated kinase in the rostral ventrolateral medulla is involved in sympathoexcitation in stroke-prone spontaneously hypertensive rats.Hypertension. 2010 Feb;55(2):291-7. doi: 10.1161/HYPERTENSIONAHA.109.138636. Epub 2010 Jan 11.
754 Dysfunction of paracellin-1 by dephosphorylation in Dahl salt-sensitive hypertensive rats.J Physiol Sci. 2006 Oct;56(5):379-83. doi: 10.2170/physiolsci.SC008906. Epub 2006 Sep 9.
755 Association of rs2271037 and rs3749585 polymorphisms in CORIN with susceptibility to hypertension in a Chinese Han population: A case-control study.Gene. 2018 Apr 20;651:79-85. doi: 10.1016/j.gene.2018.01.080. Epub 2018 Jan 31.
756 The profile of cardiac cytochrome c oxidase (COX) expression in an accelerated cardiac-hypertrophy model.J Biomed Sci. 2005;12(4):601-10. doi: 10.1007/s11373-005-7373-2. Epub 2005 Nov 10.
757 Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats.Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2455-65. doi: 10.1152/ajpheart.00512.2008. Epub 2008 Oct 24.
758 RNA silencing targeting PIN (protein inhibitor of neuronal nitric oxide synthase) attenuates the development of hypertension in young spontaneously hypertensive rats.J Am Soc Hypertens. 2014 Jan;8(1):5-13. doi: 10.1016/j.jash.2013.07.010. Epub 2013 Sep 12.
759 Differential protein expression in hypertrophic heart with and without hypertension in spontaneously hypertensive rats.Proteomics. 2006 Mar;6(6):1948-56. doi: 10.1002/pmic.200500337.
760 L-NAME-treatment alters ectonucleotidase activities in kidney membranes of rats.Life Sci. 2010 Aug 28;87(9-10):325-32. doi: 10.1016/j.lfs.2010.07.008. Epub 2010 Jul 23.
761 Anti-apoptotic and pro-survival effect of protocatechuic acid on hypertensive hearts.Chem Biol Interact. 2014 Feb 25;209:77-84. doi: 10.1016/j.cbi.2013.11.017. Epub 2013 Dec 17.
762 Identification of hypertension-related genes through an integrated genomic-transcriptomic approach.Circ Res. 2005 Apr 1;96(6):617-25. doi: 10.1161/01.RES.0000160556.52369.61. Epub 2005 Feb 24.
763 Increased GABA B receptor subtype expression in the nucleus of the solitary tract of the spontaneously hypertensive rat.J Mol Neurosci. 2008 Jun;35(2):211-24. doi: 10.1007/s12031-008-9055-9. Epub 2008 Mar 13.
764 A new ATP-sensitive potassium channel opener protects the kidney from hypertensive damage in spontaneously hypertensive rats.J Pharmacol Exp Ther. 2005 Nov;315(2):501-9. doi: 10.1124/jpet.105.089722. Epub 2005 Jul 28.
765 Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling.Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3155-3160. doi: 10.1073/pnas.1817281116. Epub 2019 Feb 4.
766 Calcification of aortic smooth muscle cells isolated from spontaneously hypertensive rats.J Pharmacol Sci. 2008 Feb;106(2):280-6. doi: 10.1254/jphs.fp0072013. Epub 2008 Feb 9.
767 Association of MYH9 Polymorphisms with Hypertension in Patients with Chronic Kidney Disease in China.Kidney Blood Press Res. 2016;41(6):956-965. doi: 10.1159/000452597. Epub 2016 Dec 8.
768 Age-associated disruption of molecular clock expression in skeletal muscle of the spontaneously hypertensive rat.PLoS One. 2011;6(11):e27168. doi: 10.1371/journal.pone.0027168. Epub 2011 Nov 4.
769 Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension.Nat Commun. 2015 Feb 17;6:6252. doi: 10.1038/ncomms7252.
770 Accumulation of 8-oxo-deoxyguanosine in cardiovascular tissues with the development of hypertension.DNA Repair (Amst). 2007 Jun 1;6(6):760-9. doi: 10.1016/j.dnarep.2007.01.003. Epub 2007 Feb 5.
771 Postnatal oxytocin treatment of spontaneously hypertensive male rats decreases blood pressure and body weight in adulthood.Neurosci Lett. 2008 Aug 1;440(2):166-9. doi: 10.1016/j.neulet.2008.05.091. Epub 2008 Jun 16.
772 Elevation of autoantibody level against PDCD11 in patients with transient ischemic attack.Oncotarget. 2017 Dec 24;9(10):8836-8848. doi: 10.18632/oncotarget.23653. eCollection 2018 Feb 6.
773 Chronic blockade of phosphatidylinositol 3-kinase in the nucleus tractus solitarii is prohypertensive in the spontaneously hypertensive rat.Hypertension. 2009 Jan;53(1):97-103. doi: 10.1161/HYPERTENSIONAHA.108.122341. Epub 2008 Nov 17.
774 Diminished expression of dihydropteridine reductase is a potent biomarker for hypertensive vessels.Proteomics. 2009 Nov;9(21):4851-8. doi: 10.1002/pmic.200800973.
775 Augmented rififylin is a risk factor linked to aberrant cardiomyocyte function, short-QT interval and hypertension.Hypertension. 2011 Apr;57(4):764-71. doi: 10.1161/HYPERTENSIONAHA.110.165803. Epub 2011 Feb 28.
776 Analysis of the genes involved in Mendelian forms of low-renin hypertension in Chinese early-onset hypertensive patients.J Hypertens. 2018 Mar;36(3):502-509. doi: 10.1097/HJH.0000000000001556.
777 Comparative changes in the blood-brain barrier and cerebral infarction of SHR and WKY rats.Am J Physiol Regul Integr Comp Physiol. 2007 May;292(5):R1881-92. doi: 10.1152/ajpregu.00761.2005. Epub 2007 Jan 18.
778 Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins.Neurobiol Dis. 2015 Sep;81:66-75. doi: 10.1016/j.nbd.2015.02.026. Epub 2015 Mar 11.
779 Left ventricular structure in relation to the human SAH gene in the European Project on Genes in Hypertension.Hypertens Res. 2009 Feb;32(2):145-51. doi: 10.1038/hr.2008.30. Epub 2009 Jan 16.
780 Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension.J Am Soc Nephrol. 2017 Dec;28(12):3563-3578. doi: 10.1681/ASN.2016090960. Epub 2017 Sep 19.
781 Adiponectin and its receptors are involved in hypertensive vascular injury.Mol Med Rep. 2018 Jan;17(1):209-215. doi: 10.3892/mmr.2017.7878. Epub 2017 Oct 25.
782 Chronic Intermittent Hypoxia-Induced Vascular Dysfunction in Rats is Reverted by N-Acetylcysteine Supplementation and Arginase Inhibition.Front Physiol. 2018 Jul 24;9:901. doi: 10.3389/fphys.2018.00901. eCollection 2018.
783 Role of Alstrm syndrome 1 in the regulation of blood pressure and renal function.JCI Insight. 2018 Nov 2;3(21):e95076. doi: 10.1172/jci.insight.95076.
784 Contribution of urinary tract infection to the burden of febrile illnesses in young children in rural Kenya.PLoS One. 2017 Mar 21;12(3):e0174199. doi: 10.1371/journal.pone.0174199. eCollection 2017.
785 Proteomic analysis reveals an impaired Ca(2+)/AQP5 pathway in the submandibular gland in hypertension.Sci Rep. 2017 Nov 6;7(1):14524. doi: 10.1038/s41598-017-15211-0.
786 The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension.Nat Commun. 2013;4:2910. doi: 10.1038/ncomms3910.
787 ARHGEF10 gene polymorphism is closely associated with the risk of ischemic stroke in Northern Han Chinese population.Neurol Res. 2017 Feb;39(2):158-164. doi: 10.1080/01616412.2016.1263175. Epub 2016 Dec 9.
788 Effect of Angiotensin II Receptor Type 1 Antibodies on Kidney Allograft Function.Iran J Kidney Dis. 2018 Mar;12(2):120-122.
789 The polymorphisms of ATOH 7, ET-1 and ACE in non-arteritic anterior ischemic optic neuropathy.Exp Eye Res. 2018 Sep;174:147-151. doi: 10.1016/j.exer.2018.05.021. Epub 2018 May 21.
790 Nutritional regulation of coupling factor 6, a novel vasoactive and proatherogenic peptide.Nutrition. 2017 May;37:74-78. doi: 10.1016/j.nut.2016.07.017. Epub 2016 Aug 6.
791 Low density lipoprotein transport through patient-specific thoracic arterial wall.Comput Biol Med. 2017 Oct 1;89:115-126. doi: 10.1016/j.compbiomed.2017.07.025. Epub 2017 Aug 3.
792 Bet 1: Can induced hypertension improve outcome following acute traumatic spinal cord injury?.Emerg Med J. 2018 Apr;35(4):270-272. doi: 10.1136/emermed-2018-207608.2.
793 Adipokine CTRP6 improves PPAR activation to alleviate angiotensin II-induced hypertension and vascular endothelial dysfunction in spontaneously hypertensive rats.Biochem Biophys Res Commun. 2017 Jan 22;482(4):727-734. doi: 10.1016/j.bbrc.2016.11.102. Epub 2016 Nov 18.
794 Relation of Coronary Artery Calcium and Extra-Coronary Aortic Calcium to Incident Hypertension (from the Multi-Ethnic Study of Atherosclerosis).Am J Cardiol. 2018 Jan 15;121(2):210-216. doi: 10.1016/j.amjcard.2017.10.018. Epub 2017 Oct 24.
795 CAMK4 gene variation is associated with hypertension in a Uygur population.Genet Mol Res. 2016 Jan 22;15(1). doi: 10.4238/gmr.15017207.
796 Central action of CART induces neuronal activation in the paraventricular and dorsomedial hypothalamus of diet-induced obese and lean mice.Neurosci Lett. 2018 Nov 1;686:175-180. doi: 10.1016/j.neulet.2018.09.015. Epub 2018 Sep 12.
797 Extracellular Calpain/Calpastatin Balance Is Involved in the Progression of Pulmonary Hypertension.Am J Respir Cell Mol Biol. 2016 Sep;55(3):337-51. doi: 10.1165/rcmb.2015-0257OC.
798 MURC deficiency in smooth muscle attenuates pulmonary hypertension.Nat Commun. 2016 Aug 22;7:12417. doi: 10.1038/ncomms12417.
799 High Frequency of Pulmonary Hypertension-Causing Gene Mutation in Chinese Patients with Chronic Thromboembolic Pulmonary Hypertension.PLoS One. 2016 Jan 28;11(1):e0147396. doi: 10.1371/journal.pone.0147396. eCollection 2016.
800 Serum cytokine profiles in patients with chronic obstructive pulmonary disease associated pulmonary hypertension identified using protein array.Cytokine. 2018 Nov;111:342-349. doi: 10.1016/j.cyto.2018.09.005. Epub 2018 Sep 28.
801 Molecular function and biological importance of CNNM family Mg2+ transporters.J Biochem. 2019 Mar 1;165(3):219-225. doi: 10.1093/jb/mvy095.
802 Human podocyte injury in the early course of hypertensive renal injury.World J Clin Cases. 2019 Nov 26;7(22):3698-3710. doi: 10.12998/wjcc.v7.i22.3698.
803 Effect of hypertension and peroxynitrite decomposition with FeTMPyP on CBF and stroke outcome.J Cereb Blood Flow Metab. 2017 Apr;37(4):1276-1285. doi: 10.1177/0271678X16654158. Epub 2016 Jan 1.
804 Associations of CFH polymorphisms and CFHR1-CFHR3 deletion with blood pressure and hypertension in Chinese population.PLoS One. 2012;7(7):e42010. doi: 10.1371/journal.pone.0042010. Epub 2012 Jul 25.
805 CHRNA3 rs6495308 genotype as an effect modifier of the association between daily cigarette consumption and hypertension in Chinese male smokers.Int J Environ Res Public Health. 2015 Apr 14;12(4):4156-69. doi: 10.3390/ijerph120404156.
806 Cross Talk Between Mitochondrial Reactive Oxygen Species and Sarcoplasmic Reticulum Calcium in Pulmonary Arterial Smooth Muscle Cells.Adv Exp Med Biol. 2017;967:289-298. doi: 10.1007/978-3-319-63245-2_17.
807 Claudin-7 Modulates Cl(-) and Na(+) Homeostasis and WNK4 Expression in Renal Collecting Duct Cells.Int J Mol Sci. 2019 Aug 3;20(15):3798. doi: 10.3390/ijms20153798.
808 Association of genetic variants with myocardial infarction in individuals with or without hypertension or diabetes mellitus.Int J Mol Med. 2009 Nov;24(5):701-9. doi: 10.3892/ijmm_00000282.
809 Genetic mapping of habitual substance use, obesity-related traits, responses to mental and physical stress, and heart rate and blood pressure measurements reveals shared genes that are overrepresented in the neural synapse.Hypertens Res. 2012 Jun;35(6):585-91. doi: 10.1038/hr.2011.233. Epub 2012 Feb 2.
810 The practice of diagnosing and reporting transfusion-associated circulatory overload: a national survey among physicians and haemovigilance officers.Transfus Med. 2018 Oct;28(5):363-370. doi: 10.1111/tme.12480. Epub 2017 Oct 23.
811 Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.Circulation. 2016 Oct 11;134(15):1105-1121. doi: 10.1161/CIRCULATIONAHA.116.023171. Epub 2016 Aug 25.
812 Optic Nerve Sheath Diameter Ultrasound Evaluation in Intensive Care Unit: Possible Role and Clinical Aspects in Neurological Critical Patients' Daily Monitoring.Biomed Res Int. 2017;2017:1621428. doi: 10.1155/2017/1621428. Epub 2017 Mar 21.
813 CXCL5 polymorphisms are associated with variable blood pressure in cardiovascular disease-free adults.Hum Genomics. 2012 Aug 2;6(1):9. doi: 10.1186/1479-7364-6-9.
814 Expression and Histopathological Significance of Disabled-2 in Aldosterone-Producing Adenoma.Horm Metab Res. 2017 Jul;49(7):520-526. doi: 10.1055/s-0043-100935. Epub 2017 May 17.
815 Urinary angiotensinogen level is correlated with blood pressure level and proteinuria in patients with masked hypertension.Clin Exp Hypertens. 2018;40(7):644-649. doi: 10.1080/10641963.2017.1416122. Epub 2018 Feb 8.
816 Hypertension and genetic variation in endothelial-specific genes.PLoS One. 2013 Apr 29;8(4):e62035. doi: 10.1371/journal.pone.0062035. Print 2013.
817 Identifications of potential therapeutic targets and drugs in angiotensin II-induced hypertension.Medicine (Baltimore). 2017 Nov;96(46):e8501. doi: 10.1097/MD.0000000000008501.
818 Reduced blood pressure after smooth muscle EFNB2 deletion and the potential association of EFNB2 mutation with human hypertension risk.Eur J Hum Genet. 2016 Dec;24(12):1817-1825. doi: 10.1038/ejhg.2016.105. Epub 2016 Aug 17.
819 Association Study of Common Variants in PFN1 With Hypertension in a Han Chinese Population: A Case-Control Study and A Follow-up Study.Am J Hypertens. 2017 Oct 1;30(10):1024-1031. doi: 10.1093/ajh/hpx089.
820 Two obesity susceptibility loci in LYPLAL1 and ETV5 independently associated with childhood hypertension in Chinese population.Gene. 2017 Sep 5;627:284-289. doi: 10.1016/j.gene.2017.06.030. Epub 2017 Jun 20.
821 Two variants in the fibulin2 gene are associated with lower systolic blood pressure and decreased risk of hypertension.PLoS One. 2012;7(8):e43051. doi: 10.1371/journal.pone.0043051. Epub 2012 Aug 13.
822 Association study between variants in the fibrinogen gene cluster, fibrinogen levels and hypertension: results from the MONICA/KORA study.Thromb Haemost. 2009 Feb;101(2):317-24.
823 FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy.Sci Rep. 2019 Apr 30;9(1):6693. doi: 10.1038/s41598-019-42328-1.
824 The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice.J Biol Chem. 2018 Jan 5;293(1):148-162. doi: 10.1074/jbc.M117.813931. Epub 2017 Nov 20.
825 Development and Validation of the Procedure-Related Neurologic Complications Risk Score for Elderly Patients with Ruptured Intracranial Aneurysm Undergoing Endovascular Treatment.World Neurosurg. 2017 Apr;100:648-657.e2. doi: 10.1016/j.wneu.2017.01.085. Epub 2017 Jan 31.
826 Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.J Mol Med (Berl). 2017 Apr;95(4):381-393. doi: 10.1007/s00109-017-1522-8. Epub 2017 Mar 6.
827 Transcranial Doppler-determined change in posterior cerebral artery blood flow velocity does not reflect vertebral artery blood flow during exercise.Am J Physiol Heart Circ Physiol. 2017 Apr 1;312(4):H827-H831. doi: 10.1152/ajpheart.00676.2016. Epub 2017 Feb 10.
828 Fibronectin type III domain containing 5 attenuates NLRP3 inflammasome activation and phenotypic transformation of adventitial fibroblasts in spontaneously hypertensive rats.J Hypertens. 2018 May;36(5):1104-1114. doi: 10.1097/HJH.0000000000001654.
829 Mechanisms in hypertension and target organ damage: Is the role of the thymus key? (Review).Int J Mol Med. 2018 Jul;42(1):3-12. doi: 10.3892/ijmm.2018.3605. Epub 2018 Mar 30.
830 Effects of hypertension and antihypertensive treatments on sulfatide levels in serum and its metabolism.Hypertens Res. 2019 May;42(5):598-609. doi: 10.1038/s41440-018-0160-z. Epub 2018 Dec 10.
831 Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.PLoS Genet. 2013;9(1):e1003087. doi: 10.1371/journal.pgen.1003087. Epub 2013 Jan 31.
832 Association Between GLCCI1 Promoter Polymorphism (Rs37972) and Post-Transplant Hypertension in Renal Transplant Recipients.Kidney Blood Press Res. 2017;42(6):1155-1163. doi: 10.1159/000485862. Epub 2017 Dec 8.
833 Integration of multi-scale molecular modeling approaches with experiments for the in silico guided design and discovery of novel hERG-Neutral antihypertensive oxazalone and imidazolone derivatives and analysis of their potential restrictive effects on cell proliferation.Eur J Med Chem. 2018 Feb 10;145:273-290. doi: 10.1016/j.ejmech.2017.12.021. Epub 2017 Dec 11.
834 Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control.Biol Sex Differ. 2018 Apr 6;9(1):14. doi: 10.1186/s13293-018-0173-y.
835 Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6.Sci Rep. 2017 Jan 20;7:41058. doi: 10.1038/srep41058.
836 Glutathione S-Transferase M1 and T1 polymorphisms and hypertension risk: an updated meta-analysis.J Hum Hypertens. 2019 Jun;33(6):454-465. doi: 10.1038/s41371-018-0133-3. Epub 2018 Nov 12.
837 Two candidate genes for two quantitative trait loci epistatically attenuate hypertension in a novel pathway.J Hypertens. 2015 Sep;33(9):1791-801; discussion 1801. doi: 10.1097/HJH.0000000000000626.
838 Differential expression profile of long non-coding RNAs in human thoracic aortic aneurysm.J Cell Biochem. 2018 Nov;119(10):7991-7997. doi: 10.1002/jcb.26670. Epub 2018 Jun 28.
839 Interaction of heat shock protein 70 (HSP70) polymorphisms and occupational hazards increases the risk of hypertension in coke oven workers.Occup Environ Med. 2018 Nov;75(11):807-813. doi: 10.1136/oemed-2018-105160. Epub 2018 Sep 14.
840 Hypertension Severity Is Associated With Impaired Cognitive Performance.J Am Heart Assoc. 2017 Jan 11;6(1):e004579. doi: 10.1161/JAHA.116.004579.
841 The A allele of the rs1990760 polymorphism in the IFIH1 gene is associated with protection for arterial hypertension in type 1 diabetic patients and with expression of this gene in human mononuclear cells.PLoS One. 2013 Dec 27;8(12):e83451. doi: 10.1371/journal.pone.0083451. eCollection 2013.
842 Krppel-like factor 15 is a key suppressor of podocyte fibrosis under rotational force-driven pressure.Exp Cell Res. 2020 Jan 1;386(1):111706. doi: 10.1016/j.yexcr.2019.111706. Epub 2019 Nov 4.
843 Prognostic Factors in Patients with an Implanted Pacemaker after 80 Years of Age in a 4-Year Follow-Up.Gerontology. 2018;64(2):107-117. doi: 10.1159/000481504. Epub 2017 Nov 15.
844 Genome Wide Association Study Identifies L3MBTL4 as a Novel Susceptibility Gene for Hypertension.Sci Rep. 2016 Aug 2;6:30811. doi: 10.1038/srep30811.
845 Validation of the G.LAB MD2200 wrist blood pressure monitor according to the European Society of Hypertension, the British Hypertension Society, and the International Organization for Standardization Protocols.Blood Press Monit. 2017 Apr;22(2):101-104. doi: 10.1097/MBP.0000000000000234.
846 The mitochondrial calcium uniporter is involved in mitochondrial calcium cycle dysfunction: Underlying mechanism of hypertension associated with mitochondrial tRNA(Ile) A4263G mutation.Int J Biochem Cell Biol. 2016 Sep;78:307-314. doi: 10.1016/j.biocel.2016.07.018. Epub 2016 Jul 25.
847 Prevalence of hypertension and associated risk factors in people with long-term spinal cord injury living in the Netherlands.Disabil Rehabil. 2017 May;39(9):919-927. doi: 10.3109/09638288.2016.1172349. Epub 2016 May 9.
848 Closed-loop regulation of arterial pressure after acute brain death.J Clin Monit Comput. 2018 Jun;32(3):429-437. doi: 10.1007/s10877-017-0033-z. Epub 2017 Jun 10.
849 Association between mitral valve prolapse and sudden sensorineural hearing loss: A case-control population-based study.PLoS One. 2018 Oct 4;13(10):e0205199. doi: 10.1371/journal.pone.0205199. eCollection 2018.
850 Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers.Eur Heart J. 2016 Jun 14;37(23):1815-22. doi: 10.1093/eurheartj/ehv522. Epub 2015 Oct 24.
851 Inhibition of SRF/myocardin reduces aortic stiffness by targeting vascular smooth muscle cell stiffening in hypertension.Cardiovasc Res. 2017 Feb;113(2):171-182. doi: 10.1093/cvr/cvw222. Epub 2016 Oct 23.
852 The mitochondrial ND1 T3308C mutation in a Chinese family with the secondary hypertension.Biochem Biophys Res Commun. 2008 Mar 28;368(1):18-22. doi: 10.1016/j.bbrc.2007.12.193. Epub 2008 Jan 14.
853 Characterization of mitochondrial NADH dehydrogenase 1 subcomplex 10 variants in cardiac muscles from normal Wistar rats and spontaneously hypertensive rats: Implications in the pathogenesis of hypertension.Mol Med Rep. 2016 Jan;13(1):961-6. doi: 10.3892/mmr.2015.4607. Epub 2015 Nov 23.
854 (Pro)renin receptor knockdown in the paraventricular nucleus of the hypothalamus attenuates hypertension development and AT(1) receptor-mediated calcium events.Am J Physiol Heart Circ Physiol. 2019 Jun 1;316(6):H1389-H1405. doi: 10.1152/ajpheart.00780.2018. Epub 2019 Mar 29.
855 Rats with a Human Mutation of NFU1 Develop Pulmonary Hypertension.Am J Respir Cell Mol Biol. 2020 Feb;62(2):231-242. doi: 10.1165/rcmb.2019-0065OC.
856 Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning.Sci Transl Med. 2016 Dec 7;8(368):368ra173. doi: 10.1126/scitranslmed.aah6571.
857 Modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7.J Hypertens. 2015 Dec;33(12):2431-42. doi: 10.1097/HJH.0000000000000723.
858 Oligonephronia and Wolf-Hirschhorn syndrome: A further observation.Am J Med Genet A. 2018 Feb;176(2):409-414. doi: 10.1002/ajmg.a.38554. Epub 2017 Nov 28.
859 Pathophysiological mechanisms of calcineurin inhibitor-induced nephrotoxicity and arterial hypertension.Physiol Res. 2017 May 4;66(2):167-180. doi: 10.33549/physiolres.933332. Epub 2016 Dec 16.
860 Stress Response Gene Nupr1 Alleviates Cyclosporin A Nephrotoxicity In Vivo.J Am Soc Nephrol. 2017 Feb;28(2):545-556. doi: 10.1681/ASN.2015080936. Epub 2016 Jul 22.
861 Morbidity After Cardiac Surgery in Patients With Adult Congenital Heart Disease in Comparison With Acquired Disease.Heart Lung Circ. 2018 Jun;27(6):739-744. doi: 10.1016/j.hlc.2017.05.133. Epub 2017 Jun 28.
862 The role of a FADS1 polymorphism in the association of fatty acid blood levels, BMI and blood pressure in young children-Analyses based on path models.PLoS One. 2017 Jul 21;12(7):e0181485. doi: 10.1371/journal.pone.0181485. eCollection 2017.
863 Persistent Organochlorine Pollutants in Plasma, Blood Pressure, and Hypertension in a Longitudinal Study.Hypertension. 2018 Jun;71(6):1258-1268. doi: 10.1161/HYPERTENSIONAHA.117.10691. Epub 2018 Apr 30.
864 Adolescent type 2 diabetes: Comparing the Pediatric Diabetes Consortium and Germany/Austria/Luxemburg Pediatric Diabetes Prospective registries.Pediatr Diabetes. 2018 Nov;19(7):1156-1163. doi: 10.1111/pedi.12712. Epub 2018 Jul 17.
865 Filtering genetic variants and placing informative priors based on putative biological function.BMC Genet. 2016 Feb 3;17 Suppl 2(Suppl 2):8. doi: 10.1186/s12863-015-0313-x.
866 Stretch-activated Piezo1 Channel in Endothelial Cells Relaxes Mouse Intrapulmonary Arteries.Am J Respir Cell Mol Biol. 2019 Jun;60(6):650-658. doi: 10.1165/rcmb.2018-0197OC.
867 Particle swarm optimization algorithm for analyzing SNP-SNP interaction of renin-angiotensin system genes against hypertension.Mol Biol Rep. 2013 Jul;40(7):4227-33. doi: 10.1007/s11033-013-2504-8. Epub 2013 May 22.
868 Hypertension Susceptibility Loci are Associated with Anthracycline-related Cardiotoxicity in Long-term Childhood Cancer Survivors.Sci Rep. 2017 Aug 29;7(1):9698. doi: 10.1038/s41598-017-09517-2.
869 Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure.Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1486-94. doi: 10.1161/ATVBAHA.114.303678. Epub 2014 May 1.
870 CPI-17-mediated contraction of vascular smooth muscle is essential for the development of hypertension in obese mice.J Genet Genomics. 2019 Mar 20;46(3):109-118. doi: 10.1016/j.jgg.2019.02.005. Epub 2019 Mar 15.
871 Spinophilin Is Indispensable for the 2B Adrenergic Receptor-Elicited Hypertensive Response.PLoS One. 2015 Aug 5;10(8):e0135030. doi: 10.1371/journal.pone.0135030. eCollection 2015.
872 Adult hemophagocytic lymphohistiocytosis with severe pulmonary hypertension and a novel perforin gene mutation.Int J Hematol. 2012 Apr;95(4):445-50. doi: 10.1007/s12185-012-1029-6. Epub 2012 Feb 23.
873 Molecular mechanisms of neuronal nitric oxide synthase in cardiac function and pathophysiology.J Physiol. 2014 Aug 1;592(15):3189-200. doi: 10.1113/jphysiol.2013.270306. Epub 2014 Apr 22.
874 Metformin prevents vascular damage in hypertension through the AMPK/ER stress pathway.Hypertens Res. 2019 Jul;42(7):960-969. doi: 10.1038/s41440-019-0212-z. Epub 2019 Jan 21.
875 SNPs rs10224002 in PRKAG2 may disturb gene expression and consequently affect hypertension.Mol Biol Rep. 2019 Apr;46(2):1617-1624. doi: 10.1007/s11033-019-04610-3. Epub 2019 Jan 28.
876 Genetic variations in MOV10 and CACNB2 are associated with hypertension in a Chinese Han population.Genet Mol Res. 2013 Dec 4;12(4):6220-7. doi: 10.4238/2013.December.4.9.
877 Preliminary study about the relationship between estimated training status and RAS polymorphisms on blood pressure and ACE activity in the elderly.J Renin Angiotensin Aldosterone Syst. 2018 Apr-Jun;19(2):1470320318782622. doi: 10.1177/1470320318782622.
878 Burden of hypertension in The Gambia: evidence from a national World Health Organization (WHO) STEP survey.Int J Epidemiol. 2018 Jun 1;47(3):860-871. doi: 10.1093/ije/dyx279.
879 Mechanisms of oxidative stress effects of the NADPH oxidase-ROS-NF-B transduction pathway and VPO1 on patients with chronic obstructive pulmonary disease combined with pulmonary hypertension.Eur Rev Med Pharmacol Sci. 2017 Aug;21(15):3459-3464.
880 Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1 depletion or imatinib treatment.Thromb Haemost. 2014 Dec;112(6):1288-303. doi: 10.1160/TH13-12-1031. Epub 2014 Sep 18.
881 Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function.EMBO Rep. 2015 May;16(5):628-37. doi: 10.15252/embr.201439846. Epub 2015 Mar 25.
882 Cerebellar Adrenomedullinergic System. Role in Cardiovascular Regulation.Adv Exp Med Biol. 2017;956:541-560. doi: 10.1007/5584_2016_48.
883 Aberrant Splicing Induced by Dysregulated Rbfox2 Produces Enhanced Function of Ca(V)1.2 Calcium Channel and Vascular Myogenic Tone in Hypertension.Hypertension. 2017 Dec;70(6):1183-1192. doi: 10.1161/HYPERTENSIONAHA.117.09301. Epub 2017 Oct 9.
884 Conditional deletion of Rcan1 predisposes to hypertension-mediated intramural hematoma and subsequent aneurysm and aortic rupture.Nat Commun. 2018 Nov 15;9(1):4795. doi: 10.1038/s41467-018-07071-7.
885 Effect of psychostimulants on blood pressure profile and endothelial function in narcolepsy.Neurology. 2018 Feb 6;90(6):e479-e491. doi: 10.1212/WNL.0000000000004911. Epub 2018 Jan 10.
886 Response Gene to Complement 32 Maintains Blood Pressure Homeostasis by Regulating -Adrenergic Receptor Expression.Circ Res. 2018 Oct 12;123(9):1080-1090. doi: 10.1161/CIRCRESAHA.118.313266.
887 Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.Vascul Pharmacol. 2018 Sep;108:15-22. doi: 10.1016/j.vph.2018.04.002. Epub 2018 Apr 11.
888 Prevalence of auto-antibodies associated to pulmonary arterial hypertension in scleroderma - A review.Autoimmun Rev. 2018 Dec;17(12):1186-1201. doi: 10.1016/j.autrev.2018.06.009. Epub 2018 Oct 12.
889 Population-based trends and risk factors of early- and late-onset preeclampsia in Taiwan 2001-2014.BMC Pregnancy Childbirth. 2018 May 31;18(1):199. doi: 10.1186/s12884-018-1845-7.
890 Longitudinal Impact of a Park-Based Afterschool Healthy Weight Program on Modifiable Cardiovascular Disease Risk Factors in Youth.J Community Health. 2018 Feb;43(1):103-116. doi: 10.1007/s10900-017-0393-9.
891 Relaxin polymorphisms associated with metabolic disturbance in patients treated with antipsychotics.J Psychopharmacol. 2012 Mar;26(3):374-9. doi: 10.1177/0269881111408965. Epub 2011 Jun 21.
892 Genetic studies on the APOA1-C3-A5 gene cluster in Asian Indians with premature coronary artery disease.Lipids Health Dis. 2008 Sep 19;7:33. doi: 10.1186/1476-511X-7-33.
893 Western diet in the perinatal period promotes dysautonomia in the offspring of adult rats.J Dev Orig Health Dis. 2017 Apr;8(2):216-225. doi: 10.1017/S2040174416000623. Epub 2016 Dec 9.
894 Risk Factors for Suboptimal Utilization of Statins and Antiplatelet Therapy in Patients Undergoing Revascularization for Symptomatic Peripheral Arterial Disease.Ann Vasc Surg. 2018 Jan;46:234-240. doi: 10.1016/j.avsg.2017.05.030. Epub 2017 Jun 8.
895 Using the Medical Research Council framework for development and evaluation of complex interventions in a low resource setting to develop a theory-based treatment support intervention delivered via SMS text message to improve blood pressure control.BMC Health Serv Res. 2018 Jan 23;18(1):33. doi: 10.1186/s12913-017-2808-9.
896 A novel autosomal dominant mutation in SOX18 resulting in a fatal case of hypotrichosis-lymphedema-telangiectasia syndrome.Am J Med Genet A. 2018 Dec;176(12):2824-2828. doi: 10.1002/ajmg.a.40532. Epub 2018 Dec 14.
897 Simultaneous validation of the SunTech CT40 automated blood pressure measurement device by the 1993 British Hypertension Society protocol and the Association for the Advancement of Medical Instrumentation/International Organization for Standardization 81060-2: 2013 standard.Blood Press Monit. 2017 Oct;22(5):298-301. doi: 10.1097/MBP.0000000000000281.
898 Molecular mechanisms in microRNA-mediated TRB3 gene and hypertension left ventricular hypertrophy.Exp Ther Med. 2017 May;13(5):1907-1911. doi: 10.3892/etm.2017.4220. Epub 2017 Mar 10.
899 Retinoblastoma-associated protein 140 as a candidate for a novel etiological gene to hypertension.Clin Exp Hypertens. 2016;38(6):533-40. doi: 10.3109/10641963.2016.1163373. Epub 2016 Jul 8.
900 Silencing salusin ameliorates heart failure in aged spontaneously hypertensive rats by ROS-relative MAPK/NF-B pathways in the paraventricular nucleus.Int J Cardiol. 2019 Apr 1;280:142-151. doi: 10.1016/j.ijcard.2018.12.020. Epub 2018 Dec 7.
901 Intracranial aneurysm risk factor genes: relationship with intracranial aneurysm risk in a Chinese Han population.Genet Mol Res. 2015 Jun 18;14(2):6865-78. doi: 10.4238/2015.June.18.30.
902 Male-specific genetic effect on hypertension and metabolic disorders.Hum Genet. 2014 Mar;133(3):311-9. doi: 10.1007/s00439-013-1382-4. Epub 2013 Oct 20.
903 Teneligliptin Prevents Cardiomyocyte Hypertrophy, Fibrosis, and Development of Hypertensive Heart Failure in Dahl Salt-Sensitive Rats.J Card Fail. 2018 Jan;24(1):53-60. doi: 10.1016/j.cardfail.2017.09.001. Epub 2017 Sep 6.
904 A multinational clinical approach to assessing the effectiveness of catheter-based ultrasound renal denervation: The RADIANCE-HTN and REQUIRE clinical study designs.Am Heart J. 2018 Jan;195:115-129. doi: 10.1016/j.ahj.2017.09.006. Epub 2017 Sep 12.
905 Correlation between chronic venous ulcer exudate proteins and clinical profile: A cross-sectional study.J Proteomics. 2019 Feb 10;192:280-290. doi: 10.1016/j.jprot.2018.09.009. Epub 2018 Sep 24.
906 Effect of genetic variant (rs11887534) in ABCG8 gene in coronary artery disease and response to atorvastatin therapy. Dis Markers. 2010;28(5):307-13.
907 Blood pressure and the new ACC/AHA hypertension guidelines.Trends Cardiovasc Med. 2020 Apr;30(3):160-164. doi: 10.1016/j.tcm.2019.05.003. Epub 2019 May 15.
908 The ACTB Variants and Alcohol Drinking Confer Joint Effect to Ischemic Stroke in Chinese Han Population.J Atheroscler Thromb. 2020 Mar 1;27(3):226-244. doi: 10.5551/jat.49536. Epub 2019 Jul 19.
909 Male mice lacking ADAMTS-16 are fertile but exhibit testes of reduced weight.Sci Rep. 2019 Nov 20;9(1):17195. doi: 10.1038/s41598-019-53900-0.
910 A Disintegrin and Metalloproteinase with Thrombospondin Motifs 18 Deficiency Leads to Visceral Adiposity and Associated Metabolic Syndrome in Mice.Am J Pathol. 2018 Feb;188(2):461-473. doi: 10.1016/j.ajpath.2017.10.020. Epub 2017 Nov 21.
911 Intra-erythrocyte cation concentrations in relation to the C1797T beta-adducin polymorphism in a general population.J Hum Hypertens. 2007 May;21(5):387-92. doi: 10.1038/sj.jhh.1002154. Epub 2007 Feb 15.
912 Missense mutations in the AFG3L2 proteolytic domain account for ?1.5% of European autosomal dominant cerebellar ataxias. Hum Mutat. 2010 Oct;31(10):1117-24. doi: 10.1002/humu.21342.
913 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.PLoS One. 2015 Oct 30;10(10):e0140496. doi: 10.1371/journal.pone.0140496. eCollection 2015.
914 Rab proteins regulate epithelial sodium channel activity in colonic epithelial HT-29 cells.Biochem Biophys Res Commun. 2005 Dec 2;337(4):1219-23. doi: 10.1016/j.bbrc.2005.09.186. Epub 2005 Oct 7.
915 Associations of White Matter Hyperintensities with Cognitive Decline: A Longitudinal Study.J Alzheimers Dis. 2020;73(2):759-768. doi: 10.3233/JAD-191005.
916 Effects of ATRAP in Renal Proximal Tubules on Angiotensin-Dependent Hypertension.J Am Heart Assoc. 2019 Apr 16;8(8):e012395. doi: 10.1161/JAHA.119.012395.
917 Missense variants of the alanine: glyoxylate aminotransferase 2 gene correlated with carotid atherosclerosis in the Japanese population.J Biol Regul Homeost Agents. 2014 Oct-Dec;28(4):605-14.
918 Polymorphism 1936A > G in the AKAP10 gene (encoding A-kinase-anchoring protein 10) is associated with higher cholesterol cord blood concentration in Polish full-term newsborns.J Perinat Med. 2013 Mar;41(2):205-10. doi: 10.1515/jpm-2012-0048.
919 Synergistic Effects of ACE Insertion/Deletion and GNB3 C825T Polymorphisms on the Efficacy of PDE-5 Inhibitor in Patients with Pulmonary Hypertension.Respiration. 2016;91(2):132-40. doi: 10.1159/000443772. Epub 2016 Jan 28.
920 Positive feedback-loop of telomerase reverse transcriptase and 15-lipoxygenase-2 promotes pulmonary hypertension.PLoS One. 2013 Dec 23;8(12):e83132. doi: 10.1371/journal.pone.0083132. eCollection 2013.
921 Serum anti mullerian hormone and renalase levels in predicting the risk of preeclampsia.Taiwan J Obstet Gynecol. 2019 Mar;58(2):188-191. doi: 10.1016/j.tjog.2019.01.003.
922 The Association of Salivary Biomarkers With the Severity of Obstructive Sleep Apnea and Concomitant Hypertension.Am J Med Sci. 2019 Jun;357(6):468-473. doi: 10.1016/j.amjms.2019.03.004. Epub 2019 Mar 22.
923 Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.Hypertension. 2012 Jun;59(6):1204-11. doi: 10.1161/HYP.0b013e31825b30f8. Epub 2012 May 7.
924 Examining the Effect of Hypertonic Saline Administered for Reduction of Intracranial Hypertension on Coagulation.J Am Coll Surg. 2020 Mar;230(3):322-330.e2. doi: 10.1016/j.jamcollsurg.2019.11.011. Epub 2019 Dec 14.
925 APOA5 rs651821 confers increased risk for hypertension in Tongdao Dong population.Clin Exp Hypertens. 2020;42(1):81-85. doi: 10.1080/10641963.2019.1590383. Epub 2019 Mar 30.
926 Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1.Diabetologia. 2001 Apr;44(4):437-43. doi: 10.1007/s001250051641.
927 Trimethylamine-N-oxide (TMAO) increased aquaporin-2 expression in spontaneously hypertensive rats.Clin Exp Hypertens. 2019;41(4):312-322. doi: 10.1080/10641963.2018.1481420. Epub 2018 Jul 9.
928 CLIC4/Arf6 Pathway.Circ Res. 2019 Jan 4;124(1):52-65. doi: 10.1161/CIRCRESAHA.118.313705.
929 Haploinsufficiency of ARHGAP42 is associated with hypertension.Eur J Hum Genet. 2019 Aug;27(8):1296-1303. doi: 10.1038/s41431-019-0382-9. Epub 2019 Mar 21.
930 Gq/p63RhoGEF interaction in RhoA/Rho kinase signaling: investigation in Gitelman's syndrome and implications with hypertension.J Endocrinol Invest. 2018 Mar;41(3):351-356. doi: 10.1007/s40618-017-0749-0. Epub 2017 Aug 24.
931 Reduced mRNA and protein content of rho guanine nucleotide exchange factor (RhoGEF) in Bartter's and Gitelman's syndromes: relevance for the pathophysiology of hypertension.Am J Hypertens. 2005 Sep;18(9 Pt 1):1200-5. doi: 10.1016/j.amjhyper.2005.03.747.
932 Six-Month Results of Treatment-Blinded Medication Titration for Hypertension Control After Randomization to Endovascular Ultrasound Renal Denervation or a Sham Procedure in the RADIANCE-HTN SOLO Trial.Circulation. 2019 May 28;139(22):2542-2553. doi: 10.1161/CIRCULATIONAHA.119.040451. Epub 2019 Mar 17.
933 Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations.Hum Mol Genet. 2009 Jun 15;18(12):2288-96. doi: 10.1093/hmg/ddp135. Epub 2009 Mar 20.
934 Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics.BMC Med Genet. 2011 Jun 17;12:83. doi: 10.1186/1471-2350-12-83.
935 Iatrogenic atrial septal defect closure after transseptal mitral valve interventions: Indications and outcomes.Catheter Cardiovasc Interv. 2019 Nov 15;94(6):829-836. doi: 10.1002/ccd.28294. Epub 2019 Apr 19.
936 Role of copper transport protein antioxidant 1 in angiotensin II-induced hypertension: a key regulator of extracellular superoxide dismutase.Hypertension. 2012 Aug;60(2):476-86. doi: 10.1161/HYPERTENSIONAHA.111.189571. Epub 2012 Jul 2.
937 MiR-192-5p in the Kidney Protects Against the Development of Hypertension.Hypertension. 2019 Feb;73(2):399-406. doi: 10.1161/HYPERTENSIONAHA.118.11875.
938 Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries.Aging Cell. 2017 Oct;16(5):1104-1113. doi: 10.1111/acel.12637. Epub 2017 Aug 9.
939 Ca2+ signalling in cardiovascular disease: the role of the plasma membrane calcium pumps.Sci China Life Sci. 2011 Aug;54(8):691-8. doi: 10.1007/s11427-011-4199-1. Epub 2011 Jul 24.
940 Intracellular signaling for vasoconstrictor coupling factor 6: novel function of beta-subunit of ATP synthase as receptor.Hypertension. 2005 Nov;46(5):1140-6. doi: 10.1161/01.HYP.0000186483.86750.85. Epub 2005 Oct 17.
941 A common genetic variant in the 3'-UTR of vacuolar H+-ATPase ATP6V0A1 creates a micro-RNA motif to alter chromogranin A processing and hypertension risk.Circ Cardiovasc Genet. 2011 Aug 1;4(4):381-9. doi: 10.1161/CIRCGENETICS.111.959767. Epub 2011 May 9.
942 Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy.Eur Heart J. 2019 Nov 1;40(42):3459-3470. doi: 10.1093/eurheartj/ehz646.
943 Analysis of treatment pathways for three chronic diseases using OMOP CDM.J Med Syst. 2018 Nov 13;42(12):260. doi: 10.1007/s10916-018-1076-5.
944 A common polymorphism rs1800247 in osteocalcin gene is associated with hypertension and diastolic blood pressure levels: the Shanghai Changfeng study.J Hum Hypertens. 2016 Nov;30(11):679-684. doi: 10.1038/jhh.2016.16. Epub 2016 Jun 2.
945 Predictive response-relevant clustering of expression data provides insights into disease processes.Nucleic Acids Res. 2010 Nov;38(20):6831-40. doi: 10.1093/nar/gkq550. Epub 2010 Jun 22.
946 Do differences exist between chronic hepatitis C genotypes 2 and 3?.Rev Soc Bras Med Trop. 2014 Mar-Apr;47(2):143-8. doi: 10.1590/0037-8682-0269-2013.
947 Signaling molecules in nonfamilial pulmonary hypertension.N Engl J Med. 2003 Feb 6;348(6):500-9. doi: 10.1056/NEJMoa021650.
948 A neural network model for constructing endophenotypes of common complex diseases: an application to male young-onset hypertension microarray data.Bioinformatics. 2009 Apr 15;25(8):981-8. doi: 10.1093/bioinformatics/btp106. Epub 2009 Feb 23.
949 Author Correction: A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.Sci Rep. 2019 Jun 28;9(1):9574. doi: 10.1038/s41598-019-45691-1.
950 Genome-Wide Meta-Analysis of Blood Pressure Response to (1)-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies).J Am Heart Assoc. 2019 Aug 20;8(16):e013115. doi: 10.1161/JAHA.119.013115. Epub 2019 Aug 19.
951 Increased Healthcare-Associated Infections in a Surgical Intensive Care Unit Related to Boarding Non-Surgical Patients.Surg Infect (Larchmt). 2019 May/Jun;20(4):332-337. doi: 10.1089/sur.2018.240. Epub 2019 Feb 15.
952 MiRNA and mRNA Profiling in Systemic Lupus Reveals a Novel Set of Cytokine - Related miRNAs and their Target Genes in Cases With and Without Renal Involvement.Kidney Blood Press Res. 2017;42(6):1322-1337. doi: 10.1159/000485987. Epub 2017 Dec 15.
953 Assessment of Relationship Between C-Reactive Protein to Albumin Ratio and Coronary Artery Disease Severity in Patients With Acute Coronary Syndrome.Angiology. 2019 Apr;70(4):361-368. doi: 10.1177/0003319717743325. Epub 2017 Nov 26.
954 A novel blood pressure modulator C1q/TNF--related protein 1 (CTRP1).BMB Rep. 2018 Dec;51(12):611-612. doi: 10.5483/BMBRep.2018.51.12.268.
955 Serum Levels of Complement-C1q/Tumor Necrosis Factor-Related Protein-3 Decreased in Patients With Acute Aortic Dissection.Am J Cardiol. 2018 Oct 1;122(7):1244-1248. doi: 10.1016/j.amjcard.2018.06.024. Epub 2018 Jul 4.
956 Replication of calpain-10 genetic association with carotid intima-media thickness.Atherosclerosis. 2009 Aug;205(2):503-5. doi: 10.1016/j.atherosclerosis.2008.12.038. Epub 2009 Jan 9.
957 Association of CASQ2 polymorphisms with sudden cardiac arrest and heart failure in patients with coronary artery disease.Heart Rhythm. 2014 Apr;11(4):646-52. doi: 10.1016/j.hrthm.2014.01.015. Epub 2014 Jan 17.
958 Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group.Am J Hypertens. 2019 Nov 15;32(12):1146-1153. doi: 10.1093/ajh/hpz150.
959 Caveolae-Mediated Activation of Mechanosensitive Chloride Channels in Pulmonary Veins Triggers Atrial Arrhythmogenesis.J Am Heart Assoc. 2019 Oct 15;8(20):e012748. doi: 10.1161/JAHA.119.012748. Epub 2019 Oct 10.
960 Association of polymorphisms of SORBS1, GCK and WISP1 with hypertension in community-dwelling Japanese individuals.Hypertens Res. 2009 May;32(5):325-31. doi: 10.1038/hr.2009.23. Epub 2009 Mar 13.
961 A common genetic variant of FCN3/CD164L2 is associated with essential hypertension in a Chinese population.Clin Exp Hypertens. 2012;34(5):377-82. doi: 10.3109/10641963.2012.665538. Epub 2012 Apr 3.
962 Interactions of CDH13 gene polymorphisms and ambient PM(10) air pollution exposure with blood pressure and hypertension in Korean men.Chemosphere. 2019 Mar;218:292-298. doi: 10.1016/j.chemosphere.2018.11.125. Epub 2018 Nov 20.
963 Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 diabetes, diabetic complications, obesity risk and hypertension in the Tunisian population.J Diabetes. 2015 Jan;7(1):102-13. doi: 10.1111/1753-0407.12147. Epub 2014 Apr 21.
964 Association of GNAS1 gene variant with hypertension depending on smoking status.Hypertension. 2002 Sep;40(3):261-5. doi: 10.1161/01.hyp.0000028490.77489.0c.
965 Angiotensin-converting enzyme inhibition augments the expression of rat elastase-2, an angiotensin II-forming enzyme.Am J Physiol Heart Circ Physiol. 2011 Aug;301(2):H565-70. doi: 10.1152/ajpheart.00534.2010. Epub 2011 May 20.
966 A new risk locus in CHCHD5 for hypertension and obesity in a Chinese child population: a cohort study.BMJ Open. 2017 Sep 11;7(9):e016241. doi: 10.1136/bmjopen-2017-016241.
967 Chromogranin A and its fragments in cardiovascular, immunometabolic, and cancer regulation.Ann N Y Acad Sci. 2019 Nov;1455(1):34-58. doi: 10.1111/nyas.14249. Epub 2019 Oct 6.
968 Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans.Circulation. 2008 Jan 29;117(4):517-25. doi: 10.1161/CIRCULATIONAHA.107.706317. Epub 2008 Jan 7.
969 Sequence variants of the aging gene CISD2 and the risk for Alzheimer's disease.J Formos Med Assoc. 2015 Jul;114(7):627-32. doi: 10.1016/j.jfma.2013.02.012. Epub 2013 Apr 8.
970 ACE2 and the Homolog Collectrin in the Modulation of Nitric Oxide and Oxidative Stress in Blood Pressure Homeostasis and Vascular Injury.Antioxid Redox Signal. 2017 Apr 20;26(12):645-659. doi: 10.1089/ars.2016.6950. Epub 2017 Jan 12.
971 Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension.Hypertens Res. 2007 Dec;30(12):1239-46. doi: 10.1291/hypres.30.1239.
972 Anti-inflammatory effects of heat-killed Lactobacillus plantarum L-137 on cardiac and adipose tissue in rats with metabolic syndrome.Sci Rep. 2018 May 25;8(1):8156. doi: 10.1038/s41598-018-26588-x.
973 Associations between polymorphisms of the CXCL12 and CNNM2 gene and hypertension risk: A case-control study.Gene. 2018 Oct 30;675:185-190. doi: 10.1016/j.gene.2018.06.107. Epub 2018 Jul 2.
974 Risk factors between intracranial-extracranial atherosclerosis and anterior-posterior circulation stroke in ischaemic stroke.Neurol Res. 2017 Jan;39(1):30-35. doi: 10.1080/01616412.2016.1250856. Epub 2016 Oct 31.
975 Unexpected phenotypic effects of a transgene integration causing a knockout of the endogenous Contactin-5 gene in mice.Transgenic Res. 2018 Feb;27(1):1-13. doi: 10.1007/s11248-017-0053-y. Epub 2017 Dec 20.
976 Genetic predictors of glucocorticoid-induced hypertension in children with acute lymphoblastic leukemia.Pharmacogenet Genomics. 2008 Jun;18(6):507-14. doi: 10.1097/FPC.0b013e3282fc5801.
977 Renoprotective effects of carvedilol in hypertensive-stroke prone rats may involve inhibition of TGF beta expression.Br J Pharmacol. 2001 Nov;134(5):977-84. doi: 10.1038/sj.bjp.0704329.
978 Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome.Am J Med Genet C Semin Med Genet. 2017 Mar;175(1):40-47. doi: 10.1002/ajmg.c.31553.
979 Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort).J Am Coll Cardiol. 2013 Aug 27;62(9):789-98. doi: 10.1016/j.jacc.2013.01.103. Epub 2013 May 30.
980 Microangiopathy underlying mixed-location intracerebral hemorrhages/microbleeds: A PiB-PET study.Neurology. 2019 Feb 19;92(8):e774-e781. doi: 10.1212/WNL.0000000000006953. Epub 2019 Jan 23.
981 Evaluation of 10 AMD Associated Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes.PLoS One. 2016 Sep 19;11(9):e0162296. doi: 10.1371/journal.pone.0162296. eCollection 2016.
982 Hypertension-related, calcium-regulated gene (HCaRG/COMMD5) and kidney diseases: HCaRG accelerates tubular repair.J Nephrol. 2014 Aug;27(4):351-60. doi: 10.1007/s40620-014-0054-3. Epub 2014 Feb 11.
983 Whole genome resequencing identifies the CPQ gene as a determinant of ascites syndrome in broilers.PLoS One. 2018 Jan 2;13(1):e0189544. doi: 10.1371/journal.pone.0189544. eCollection 2018.
984 TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.J Hypertens. 2015 Jun;33(6):1301-9. doi: 10.1097/HJH.0000000000000541.
985 Elevated Serum Uric Acid Is Associated With Greater Risk for Hypertension and Diabetic Kidney Diseases in Obese Adolescents With Type 2 Diabetes: An Observational Analysis From the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study.Diabetes Care. 2019 Jun;42(6):1120-1128. doi: 10.2337/dc18-2147. Epub 2019 Apr 9.
986 Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall.Nat Commun. 2017 Apr 10;8:14807. doi: 10.1038/ncomms14807.
987 Chromosome 17q23: a locus for cardiovascular disease.Clin Exp Pharmacol Physiol. 1993 May;20(5):279-82. doi: 10.1111/j.1440-1681.1993.tb01683.x.
988 Increased risk for atherosclerosis of various macrophage scavenger receptor 1 alleles.Genet Test Mol Biomarkers. 2009 Oct;13(5):583-7. doi: 10.1089/gtmb.2009.0048.
989 Dietary Acid Load and Potassium Intake Associate with Blood Pressure and Hypertension Prevalence in a Representative Sample of the German Adult Population.Nutrients. 2018 Jan 19;10(1):103. doi: 10.3390/nu10010103.
990 Neuropeptide Y signal peptide Pro7 substitution protects against coronary artery atherosclerosis: the Helsinki Sudden Death Study.Atherosclerosis. 2008 Aug;199(2):445-50. doi: 10.1016/j.atherosclerosis.2007.10.021. Epub 2007 Dec 4.
991 Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.Hypertension. 2017 Jan;69(1):51-59. doi: 10.1161/HYPERTENSIONAHA.116.08267. Epub 2016 Oct 31.
992 Lipoprotein lipase gene is linked and associated with hypertension in Taiwan young-onset hypertension genetic study.J Biomed Sci. 2005;12(4):651-8. doi: 10.1007/s11373-005-7707-0. Epub 2005 Nov 10.
993 3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.PLoS One. 2015 Jul 6;10(7):e0131125. doi: 10.1371/journal.pone.0131125. eCollection 2015.
994 Increased cortical capillary transit time heterogeneity in Alzheimer's disease: a DSC-MRI perfusion study.Neurobiol Aging. 2017 Feb;50:107-118. doi: 10.1016/j.neurobiolaging.2016.11.004. Epub 2016 Nov 19.
995 Cortisol Secretion, Sensitivity, and Activity Are Associated With Hypertension in Postmenopausal Eucortisolemic Women.J Clin Endocrinol Metab. 2019 Oct 1;104(10):4441-4448. doi: 10.1210/jc.2019-00037.
996 Effects of endothelin 3 on diastolic blood pressure of pithed Sprague-Dawley, Wistar Kyoto, and spontaneously hypertensive rats before and after pretreatment with nifedipine.Can J Physiol Pharmacol. 1991 Apr;69(4):531-5. doi: 10.1139/y91-080.
997 Mechanism of action of Profilin-1 and Fibulin-3 in vascular remodeling in hypertensive rats.Eur Rev Med Pharmacol Sci. 2019 Sep;23(18):8101-8108. doi: 10.26355/eurrev_201909_19028.
998 Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism.Sci Rep. 2018 Sep 27;8(1):14497. doi: 10.1038/s41598-018-32836-x.
999 Minoxidil versus placebo in the treatment of arterial wall hypertrophy in children with Williams Beuren Syndrome: a randomized controlled trial.BMC Pediatr. 2019 May 28;19(1):170. doi: 10.1186/s12887-019-1544-1.
1000 Metabolic and Cardiovascular Benefits and Risks of EMD386088-A 5-HT(6) Receptor Partial Agonist and Dopamine Transporter Inhibitor.Front Neurosci. 2017 Feb 8;11:50. doi: 10.3389/fnins.2017.00050. eCollection 2017.
1001 Adropin and irisin in arterial hypertension, diabetes mellitus and chronic kidney disease.Adv Clin Exp Med. 2019 Nov;28(11):1571-1575. doi: 10.17219/acem/104551.
1002 Hypertension in dialysis patients: a consensus document by the European Renal and Cardiovascular Medicine (EURECA-m) working group of the European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) and the Hypertension and the Kidney working group of the European Society of Hypertension (ESH).J Hypertens. 2017 Apr;35(4):657-676. doi: 10.1097/HJH.0000000000001283.
1003 Spironolactone-induced degradation of the TFIIH core complex XPB subunit suppresses NF-B and AP-1 signalling.Cardiovasc Res. 2018 Jan 1;114(1):65-76. doi: 10.1093/cvr/cvx198.
1004 Prediction of incident hypertension and arterial stiffness using the non-insulin-based metabolic score for insulin resistance (METS-IR) index.J Clin Hypertens (Greenwich). 2019 Aug;21(8):1063-1070. doi: 10.1111/jch.13614. Epub 2019 Jul 18.
1005 The clinical relevance of autoantibodies in scleroderma.Arthritis Res Ther. 2003;5(2):80-93. doi: 10.1186/ar628. Epub 2003 Feb 12.
1006 The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.Nat Commun. 2019 Sep 12;10(1):4143. doi: 10.1038/s41467-019-12226-1.
1007 Peripheral artery disease, redox signaling, oxidative stress - Basic and clinical aspects.Redox Biol. 2017 Aug;12:787-797. doi: 10.1016/j.redox.2017.04.017. Epub 2017 Apr 13.
1008 Fibrosis-4 index at diagnosis can predict all-cause mortality in patients with rheumatoid arthritis: A retrospective monocentric study.Mod Rheumatol. 2020 Jan;30(1):70-77. doi: 10.1080/14397595.2018.1558760. Epub 2019 Jan 15.
1009 Screening strategies for hypertension: a systematic review protocol.BMJ Open. 2019 Jan 15;9(1):e025043. doi: 10.1136/bmjopen-2018-025043.
1010 A genetic variant in the gene encoding fibrinogen beta chain predicted development of hypertension in Chinese men.Thromb Haemost. 2010 Apr;103(4):728-35. doi: 10.1160/TH09-10-0692. Epub 2010 Feb 2.
1011 Genetic analyses of diverse populations improves discovery for complex traits.Nature. 2019 Jun;570(7762):514-518. doi: 10.1038/s41586-019-1310-4. Epub 2019 Jun 19.
1012 Congenital lactic acidosis, cerebral cysts and pulmonary hypertension in an infant with FOXRED1 related complex I deficiency.Mol Genet Metab Rep. 2019 Jan 18;18:32-38. doi: 10.1016/j.ymgmr.2018.12.006. eCollection 2019 Mar.
1013 miR-1 is increased in pulmonary hypertension and downregulates Kv1.5 channels in rat pulmonary arteries.J Physiol. 2019 Feb;597(4):1185-1197. doi: 10.1113/JP276054. Epub 2018 Jun 21.
1014 Endothelial Gata5 transcription factor regulates blood pressure.Nat Commun. 2015 Nov 30;6:8835. doi: 10.1038/ncomms9835.
1015 Mortality causes and trends associated with giant cell arteritis: analysis of the French national death certificate database (1980-2011).Rheumatology (Oxford). 2018 Jun 1;57(6):1047-1055. doi: 10.1093/rheumatology/key028.
1016 Downregulation of Brain G12 Attenuates Angiotensin II-Dependent Hypertension.Am J Hypertens. 2020 Feb 22;33(2):198-204. doi: 10.1093/ajh/hpz176.
1017 G Protein Subunit 14 Mediates Fibroblast Growth Factor 2-Induced Cellular Responses in Human Endothelial Cells.J Cell Physiol. 2019 Jul;234(7):10184-10195. doi: 10.1002/jcp.27688. Epub 2018 Nov 1.
1018 GNAI2 polymorphic variance associates with salt sensitivity of blood pressure in the Genetic Epidemiology Network of Salt Sensitivity study.Physiol Genomics. 2018 Sep 1;50(9):724-725. doi: 10.1152/physiolgenomics.00141.2017. Epub 2018 Jun 15.
1019 Serum aminotransferases in nonalcoholic fatty liver disease are a signature of liver metabolic perturbations at the amino acid and Krebs cycle level.Am J Clin Nutr. 2016 Feb;103(2):422-34. doi: 10.3945/ajcn.115.118695. Epub 2016 Jan 20.
1020 20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (G(q)) to Affect Vascular Function and Trigger Hypertension.Circ Res. 2017 May 26;120(11):1776-1788. doi: 10.1161/CIRCRESAHA.116.310525. Epub 2017 Mar 21.
1021 Hypertension susceptibility genes on chromosome 2p24-p25 in a general Japanese population.J Hypertens. 2005 May;23(5):955-60. doi: 10.1097/01.hjh.0000166835.70935.3c.
1022 Effects of high and low sodium diet on blood pressure and heart rate in mice lacking the functional grainyhead-like 1 gene.Physiol Res. 2017 Mar 31;66(1):163-165. doi: 10.33549/physiolres.933298. Epub 2016 Oct 26.
1023 In-utero cold stress causes elevation of blood pressure via impaired vascular dopamine D(1) receptor in offspring.Clin Exp Hypertens. 2020;42(2):99-104. doi: 10.1080/10641963.2019.1571603. Epub 2019 Jan 30.
1024 [Association of -63A/C polymorphism of glutathione S-transferase M3 gene with essential hypertension in Chinese population].Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Oct;24(5):582-5.
1025 Glutathione S-transferase variants and hypertension.J Hypertens. 2008 Jul;26(7):1343-52. doi: 10.1097/HJH.0b013e3282fe1d67.
1026 Haplotype-based case-control study of the association between the guanylate cyclase activator 2B (GUCA2B, Uroguanylin) gene and essential hypertension.Hypertens Res. 2007 Sep;30(9):789-96. doi: 10.1291/hypres.30.789.
1027 Adducin in essential hypertension.FEBS Lett. 1998 Jun 23;430(1-2):41-4. doi: 10.1016/s0014-5793(98)00457-8.
1028 A paired-sibling analysis of the XbaI polymorphism in the muscle glycogen synthase gene.Diabetologia. 1999 Sep;42(9):1138-45. doi: 10.1007/s001250051282.
1029 Evolutionary context for the association of -globin, serum uric acid, and hypertension in African Americans.BMC Med Genet. 2015 Nov 5;16:103. doi: 10.1186/s12881-015-0249-z.
1030 The role of 3'-untranslated region (3'-UTR) mediated mRNA stability in cardiovascular pathophysiology.Mol Cell Biochem. 2001 Aug;224(1-2):53-67. doi: 10.1023/a:1011982932645.
1031 Low-dose sustained-release deoxycorticosterone acetate-induced hypertension in Bama miniature pigs for renal sympathetic nerve denervation.J Am Soc Hypertens. 2017 May;11(5):314-320. doi: 10.1016/j.jash.2017.02.006. Epub 2017 Mar 2.
1032 Role of the immediate early response 3 (IER3) gene in cellular stress response, inflammation and tumorigenesis.Eur J Cell Biol. 2011 Jun-Jul;90(6-7):545-52. doi: 10.1016/j.ejcb.2010.10.002. Epub 2010 Nov 26.
1033 Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.PLoS Genet. 2010 Oct 28;6(10):e1001177. doi: 10.1371/journal.pgen.1001177.
1034 Association of polymorphisms of BTN2A1 and ILF3 with myocardial infarction in Japanese individuals with or without hypertension, diabetes mellitus or chronic kidney disease.Int J Mol Med. 2011 May;27(5):745-52. doi: 10.3892/ijmm.2011.623. Epub 2011 Feb 23.
1035 Research-grade data in the real world: challenges and opportunities in data quality from a pragmatic trial in community-based practices.J Am Med Inform Assoc. 2019 Aug 1;26(8-9):847-854. doi: 10.1093/jamia/ocz062.
1036 [Inhibins and Activin A in hypertensive Disorders of Pregnancy and HELLP-Syndrome].Zentralbl Gynakol. 2004 Jun;126(3):148-53. doi: 10.1055/s-2004-822592.
1037 Privately insured adults in HDHP with higher deductibles reduce rates of primary care and preventive services.Transl Behav Med. 2018 May 23;8(3):375-385. doi: 10.1093/tbm/ibx076.
1038 Functional Inducible Nitric Oxide Synthase Gene Variants Associate With Hypertension: A Case-Control Study in a Finnish Population-The TAMRISK Study.Medicine (Baltimore). 2015 Nov;94(46):e1958. doi: 10.1097/MD.0000000000001958.
1039 Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients.BMC Med Genet. 2009 Dec 17;10:140. doi: 10.1186/1471-2350-10-140.
1040 G protein-coupled receptor accessory proteins and signaling: pharmacogenomic insights.Methods Mol Biol. 2014;1175:121-52. doi: 10.1007/978-1-4939-0956-8_7.
1041 Higher High Density Lipoprotein 2 (HDL2) to Total HDL Cholesterol Ratio Is Associated with a Lower Risk for Incident Hypertension.Diabetes Metab J. 2019 Feb;43(1):114-122. doi: 10.4093/dmj.2018.0053. Epub 2018 Sep 28.
1042 Kalirin: a novel genetic risk factor for ischemic stroke.Hum Genet. 2010 Mar;127(5):513-23. doi: 10.1007/s00439-010-0790-y. Epub 2010 Jan 28.
1043 Common charge-shift mutation Glu65Lys in K+ channel ?Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease.Am J Nephrol. 2010;32(5):414-24. doi: 10.1159/000320131. Epub 2010 Sep 23.
1044 Gene-environmental effects behind leukoaraiosis: a silent genetic variant of the kinesin protein can be activated in a subject with poorly controlled long-lasting hypertension.Clin Biochem. 2009 May;42(7-8):630-3. doi: 10.1016/j.clinbiochem.2008.11.003. Epub 2008 Nov 18.
1045 Association between killer cell immunoglobulin-like receptor 2DS5 gene with essential hypertension in the Chinese Han patients.Int J Immunogenet. 2017 Dec;44(6):343-349. doi: 10.1111/iji.12342. Epub 2017 Nov 3.
1046 Placental and serum levels of human Klotho in severe preeclampsia: A potential sensitive biomarker.Placenta. 2019 Sep 15;85:49-55. doi: 10.1016/j.placenta.2019.08.084. Epub 2019 Aug 19.
1047 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.PLoS Genet. 2011 Feb 10;7(2):e1001300. doi: 10.1371/journal.pgen.1001300.
1048 Transcriptome reveals the overexpression of a kallikrein gene cluster (KLK1/3/7/8/12) in the Tibetans with high altitude-associated polycythemia.Int J Mol Med. 2017 Feb;39(2):287-296. doi: 10.3892/ijmm.2016.2830. Epub 2016 Dec 14.
1049 The role of the 11beta-hydroxysteroid dehydrogenase type 2 in human hypertension.J Hypertens. 2000 Mar;18(3):241-8. doi: 10.1097/00004872-200018030-00001.
1050 The association of the K121Q polymorphism of the plasma cell glycoprotein-1 gene with type 2 diabetes and hypertension depends on size at birth.J Clin Endocrinol Metab. 2004 May;89(5):2044-7. doi: 10.1210/jc.2003-031350.
1051 LEP 3'HVR is associated with obesity and leptin levels in Brazilian individuals.Mol Genet Metab. 2006 Dec;89(4):374-80. doi: 10.1016/j.ymgme.2006.04.012. Epub 2006 Jun 9.
1052 Global DNA methylation changes in blood of patients with essential hypertension.Med Sci Monit. 2010 Mar;16(3):CR149-155.
1053 Association of LIPC -250G/A and -514C/T polymorphisms and hypertension: a systematic review and meta-analysis.Lipids Health Dis. 2018 Oct 15;17(1):238. doi: 10.1186/s12944-018-0884-4.
1054 Lamin A/C negatively regulated by miR-124-3p modulates apoptosis of vascular smooth muscle cells during cyclic stretch application in rats.Acta Physiol (Oxf). 2020 Mar;228(3):e13374. doi: 10.1111/apha.13374. Epub 2019 Sep 27.
1055 Association of a polymorphism in the lipin 1 gene with systolic blood pressure in men.Am J Hypertens. 2008 May;21(5):539-45. doi: 10.1038/ajh.2008.21. Epub 2008 Mar 13.
1056 Intracranial pressure variability: relation to clinical outcome, intracranial pressure-volume index, cerebrovascular reactivity and blood pressure variability.J Clin Monit Comput. 2020 Aug;34(4):733-741. doi: 10.1007/s10877-019-00387-9. Epub 2019 Sep 19.
1057 MAP3K kinases and kidney injury.Nefrologia (Engl Ed). 2019 Nov-Dec;39(6):568-580. doi: 10.1016/j.nefro.2019.03.004. Epub 2019 Jun 10.
1058 The STOP-BANG questionnaire shows an insufficient specificity for detecting obstructive sleep apnea in patients with atrial fibrillation.J Sleep Res. 2018 Dec;27(6):e12702. doi: 10.1111/jsr.12702. Epub 2018 Apr 22.
1059 Auto positive airway pressure therapy reduces pulmonary pressures in adults admitted for acute heart failure with pulmonary hypertension and obstructive sleep apnea. The ASAP-HF Pilot Trial.Sleep. 2019 Jul 8;42(7):zsz100. doi: 10.1093/sleep/zsz100.
1060 Associations of MicroRNA Polymorphisms (miR-146a, miR-196a2, and miR-499) with the Risk of Hypertension in the Korean Population.Genet Test Mol Biomarkers. 2016 Aug;20(8):420-6. doi: 10.1089/gtmb.2016.0039. Epub 2016 Jul 5.
1061 Activation of DNA demethylases attenuates aging-associated arterial stiffening and hypertension.Aging Cell. 2018 Aug;17(4):e12762. doi: 10.1111/acel.12762. Epub 2018 Apr 16.
1062 Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels.J Clin Invest. 2002 Jul;110(2):203-8. doi: 10.1172/JCI15672.
1063 Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension.FASEB J. 2010 Jun;24(6):1780-8. doi: 10.1096/fj.09-146589. Epub 2010 Jan 19.
1064 Implication of chromosome 18 in hypertension by sibling pair and association analyses: putative involvement of the RKHD2 gene.Hypertension. 2006 Nov;48(5):883-91. doi: 10.1161/01.HYP.0000244085.52918.a0. Epub 2006 Oct 2.
1065 Single Nucleotide Polymorphisms (SNPs) Genotyping Reveals that Mfn2 Polymorphisms are Associated with Thoracic Aortic Dissection in Han Chinese Population.Med Sci Monit. 2019 Apr 3;25:2419-2428. doi: 10.12659/MSM.915272.
1066 Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome.Hum Mol Genet. 2005 May 1;14(9):1109-18. doi: 10.1093/hmg/ddi123. Epub 2005 Mar 16.
1067 Arsenic methylation capability and hypertension risk in subjects living in arseniasis-hyperendemic areas in southwestern Taiwan.Toxicol Appl Pharmacol. 2007 Jan 15;218(2):135-42. doi: 10.1016/j.taap.2006.10.022. Epub 2006 Oct 28.
1068 Right Ventricular Tissue Doppler Myocardial Performance Index in Children with Pulmonary Hypertension: Relation to Invasive Hemodynamics.Pediatr Cardiol. 2018 Jan;39(1):98-104. doi: 10.1007/s00246-017-1733-3. Epub 2017 Oct 4.
1069 Expression of the recessive glomerulosclerosis gene Mpv17 regulates MMP-2 expression in fibroblasts, the kidney, and the inner ear of mice.Mol Biol Cell. 1998 Jul;9(7):1675-82. doi: 10.1091/mbc.9.7.1675.
1070 Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension.Nat Med. 2019 Nov;25(11):1733-1738. doi: 10.1038/s41591-019-0622-0. Epub 2019 Nov 7.
1071 MTHFD1 promoter hypermethylation increases the risk of hypertension.Clin Exp Hypertens. 2019;41(5):422-427. doi: 10.1080/10641963.2018.1501057. Epub 2018 Sep 5.
1072 Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.Hum Mol Genet. 2007 Dec 15;16(24):3017-26. doi: 10.1093/hmg/ddm260. Epub 2007 Sep 12.
1073 Expression of interferon inducible genes following Hantaan virus infection as a mechanism of resistance in A549 cells.Virus Genes. 2003 Jan;26(1):31-8. doi: 10.1023/a:1022373904357.
1074 Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet.Cardiovasc Res. 2018 Aug 1;114(10):1372-1384. doi: 10.1093/cvr/cvy082.
1075 Ventricular myosin light chain 1 is developmentally regulated and does not change in hypertension.Nucleic Acids Res. 1989 Apr 11;17(7):2753-67. doi: 10.1093/nar/17.7.2753.
1076 The potential role of myosin motor proteins in mediating the subcellular distribution of NHE3 in the renal proximal tubule.Am J Physiol Renal Physiol. 2019 May 1;316(5):F986-F992. doi: 10.1152/ajprenal.00577.2018. Epub 2019 Mar 13.
1077 Association of serum levels of p,p'- Dichlorodiphenyldichloroethylene (DDE) with type 2 diabetes in African American and Caucasian adult men from agricultural (Delta) and non-agricultural (non-Delta) regions of Mississippi.J Toxicol Environ Health A. 2019;82(6):387-400. doi: 10.1080/15287394.2019.1610678. Epub 2019 May 7.
1078 NOX2-derived reactive oxygen species in immune cells exacerbates salt-sensitive hypertension.Free Radic Biol Med. 2020 Jan;146:333-339. doi: 10.1016/j.freeradbiomed.2019.11.014. Epub 2019 Nov 12.
1079 Interaction between mitochondrial NADH dehydrogenase subunit-2 5178 C > A and clinical risk factors on the susceptibility of essential hypertension in Chinese population.BMC Med Genet. 2019 Jul 5;20(1):121. doi: 10.1186/s12881-019-0838-3.
1080 Deletion of Nedd4-2 results in progressive kidney disease in mice.Cell Death Differ. 2017 Dec;24(12):2150-2160. doi: 10.1038/cdd.2017.137. Epub 2017 Sep 1.
1081 The influence of exercise on albumin excretion rate in borderline hypertensives and in offspring of hypertensive parents.J Hum Hypertens. 1997 Feb;11(2):119-23. doi: 10.1038/sj.jhh.1000388.
1082 Altered expression of Aquaporin-2 in one-kidney, one-clip hypertension.Life Sci. 2018 Sep 1;208:72-78. doi: 10.1016/j.lfs.2018.07.020. Epub 2018 Jul 17.
1083 Regulation of soluble guanylyl cyclase-alpha1 expression in chronic hypoxia-induced pulmonary hypertension: role of NFATc3 and HuR.Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L475-86. doi: 10.1152/ajplung.00060.2009. Epub 2009 Jul 10.
1084 E4BP4 inhibits AngII-induced apoptosis in H9c2 cardiomyoblasts by activating the PI3K-Akt pathway and promoting calcium uptake.Exp Cell Res. 2018 Feb 15;363(2):227-234. doi: 10.1016/j.yexcr.2018.01.012. Epub 2018 Jan 10.
1085 Molecular Basis for Dysregulated Activation of NKX2-5 in the Vascular Remodeling of Systemic Sclerosis.Arthritis Rheumatol. 2018 Jun;70(6):920-931. doi: 10.1002/art.40419. Epub 2018 Apr 24.
1086 NLRC3 inhibits MCT-induced pulmonary hypertension in rats via attenuating PI3K activation.J Cell Physiol. 2019 Sep;234(9):15963-15976. doi: 10.1002/jcp.28255. Epub 2019 Feb 14.
1087 Sex-specific effects of NLRP6/AVR and ADM loci on susceptibility to essential hypertension in a Sardinian population.PLoS One. 2013 Oct 11;8(10):e77562. doi: 10.1371/journal.pone.0077562. eCollection 2013.
1088 Arterial compliance by cuff sphygmomanometer. Application to hypertension and early changes in subjects at genetic risk.Hypertension. 1996 Oct;28(4):599-603. doi: 10.1161/01.hyp.28.4.599.
1089 Genome-wide association study identifies loci and candidate genes for non-idiopathic pulmonary hypertensionin Eastern Chinese Han population.BMC Pulm Med. 2018 Oct 5;18(1):158. doi: 10.1186/s12890-018-0719-0.
1090 Vascular Biology of Superoxide-Generating NADPH Oxidase 5-Implications in Hypertension and Cardiovascular Disease.Antioxid Redox Signal. 2019 Mar 1;30(7):1027-1040. doi: 10.1089/ars.2018.7583. Epub 2018 Nov 15.
1091 Genetic polymorphism of NPHS1 modifies the clinical manifestations of Ig A nephropathy.Lab Invest. 2003 Aug;83(8):1193-200. doi: 10.1097/01.lab.0000080600.49276.31.
1092 Linkage analysis of chromosome 1 with essential hypertension and blood pressure quantitative traits in Chinese families.Ann Hum Genet. 2005 Jan;69(Pt 1):45-54. doi: 10.1046/j.1529-8817.2004.00136.x.
1093 Human genotyping and an experimental model reveal NPR-C as a possible contributor to morbidity in coarctation of the aorta.Physiol Genomics. 2019 Jun 1;51(6):177-185. doi: 10.1152/physiolgenomics.00049.2018. Epub 2019 Apr 19.
1094 Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass.Nat Genet. 2008 May;40(5):546-52. doi: 10.1038/ng.134.
1095 Haptoglobin phenotypes with weak antioxidant capacity increase risk factors of cardiovascular disease in Ghanaian HIV-infected patients on highly active antiretroviral therapy.Trop Med Int Health. 2019 Jun;24(6):766-774. doi: 10.1111/tmi.13229. Epub 2019 Mar 21.
1096 P3H4 affects renal carcinoma through up-regulating miR-1/133a.Eur Rev Med Pharmacol Sci. 2018 Aug;22(16):5180-5186. doi: 10.26355/eurrev_201808_15714.
1097 Operational Differences in Plant-Based Diet Indices Affect the Ability to Detect Associations with Incident Hypertension in Middle-Aged US Adults.J Nutr. 2020 Apr 1;150(4):842-850. doi: 10.1093/jn/nxz275.
1098 Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension.J Psychiatr Res. 2017 Jan;84:27-34. doi: 10.1016/j.jpsychires.2016.09.015. Epub 2016 Sep 17.
1099 Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers.PLoS One. 2019 Sep 18;14(9):e0221957. doi: 10.1371/journal.pone.0221957. eCollection 2019.
1100 A brief submaximal isometric exercise test 'unmasks' systolic and diastolic masked hypertension.J Hypertens. 2019 Apr;37(4):710-719. doi: 10.1097/HJH.0000000000001943.
1101 An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension.Hum Mol Genet. 2007 Jul 15;16(14):1752-64. doi: 10.1093/hmg/ddm123. Epub 2007 Jun 21.
1102 Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease.Pharmacol Rev. 2018 Jul;70(3):446-474. doi: 10.1124/pr.117.015354.
1103 The association of endothelin-1 levels with renal survival in polycystic kidney disease patients.J Nephrol. 2019 Feb;32(1):83-91. doi: 10.1007/s40620-018-0514-2. Epub 2018 Jul 18.
1104 Increased expression and activity of phospholipase C in renal arterioles of young spontaneously hypertensive rats.Am J Hypertens. 2007 Jan;20(1):38-43. doi: 10.1016/j.amjhyper.2006.06.009.
1105 Genetic variations in CYP17A1, CACNB2 and PLEKHA7 are associated with blood pressure and/or hypertension in She ethnic minority of China.Atherosclerosis. 2011 Dec;219(2):709-14. doi: 10.1016/j.atherosclerosis.2011.09.006. Epub 2011 Sep 16.
1106 Impact of hypertension on retinal capillary microvasculature using optical coherence tomographic angiography.J Hypertens. 2019 Mar;37(3):572-580. doi: 10.1097/HJH.0000000000001916.
1107 Risk factors for hypertension as measured by the Canada Health Survey.Health Rep. 1993;5(4):419-28.
1108 Serum podocalyxin levels correlate with carotid intima media thickness, implicating its role as a novel biomarker for atherosclerosis.Sci Rep. 2018 Jan 10;8(1):245. doi: 10.1038/s41598-017-18647-6.
1109 The impact of antihypertensive pharmacotherapy on interplay between protein-bound uremic toxin (indoxyl sulfate) and markers of inflammation in patients with chronic kidney disease.Int Urol Nephrol. 2019 Mar;51(3):491-502. doi: 10.1007/s11255-018-02064-3. Epub 2019 Jan 7.
1110 Platelet morphology and plasma indices of platelet activation in essential hypertension: effects of amlodipine-based antihypertensive therapy. Ann Med. 2004;36(7):552-7. doi: 10.1080/07853890410017386.
1111 Cytochrome P450 1B1 Is Critical for Neointimal Growth in Wire-Injured Carotid Artery of Male Mice.J Am Heart Assoc. 2018 Sep 18;7(18):e010065. doi: 10.1161/JAHA.118.010065.
1112 A model-integrated multipoint Bayesian analysis of hypertension in the Framingham Heart Study data finds little evidence of linkage.BMC Genet. 2003 Dec 31;4 Suppl 1(Suppl 1):S75. doi: 10.1186/1471-2156-4-S1-S75.
1113 Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response.Sci Rep. 2019 Nov 21;9(1):17323. doi: 10.1038/s41598-019-53345-5.
1114 Extracorporeal Membrane Oxygenation Support in Trauma Versus Nontrauma Patients with Noninfectious Acute Respiratory Failure.Artif Organs. 2017 May;41(5):431-439. doi: 10.1111/aor.12794. Epub 2016 Nov 28.
1115 Entropy-based measures of EEG arousals as biomarkers for sleep dynamics: applications to hypertension.Sleep. 2008 Jul;31(7):935-43.
1116 Effects of miR-155 on hypertensive rats via regulating vascular mesangial hyperplasia.Eur Rev Med Pharmacol Sci. 2018 Nov;22(21):7431-7438. doi: 10.26355/eurrev_201811_16283.
1117 Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate. J Clin Invest. 2000 Nov;106(10):1281-90. doi: 10.1172/JCI7236.
1118 Single nucleotide polymorphisms in protein tyrosine phosphatase 1beta (PTPN1) are associated with essential hypertension and obesity.Hum Mol Genet. 2004 Sep 1;13(17):1885-92. doi: 10.1093/hmg/ddh196. Epub 2004 Jun 30.
1119 Serum pentraxin-3 levels and flow-mediated dilation in dipper and non-dipper hypertension.J Clin Lab Anal. 2019 Mar;33(3):e22718. doi: 10.1002/jcla.22718. Epub 2018 Nov 9.
1120 Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.Am J Hypertens. 2010 Jan;23(1):70-7. doi: 10.1038/ajh.2009.190. Epub 2009 Oct 22.
1121 Genetic susceptibility to anthracycline-related congestive heart failure in survivors of haematopoietic cell transplantation.Br J Haematol. 2013 Oct;163(2):205-13. doi: 10.1111/bjh.12516. Epub 2013 Aug 8.
1122 Role of immune factors in angiotensin II-induced hypertension and renal damage in Dahl salt-sensitive rats.Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1;314(3):R323-R333. doi: 10.1152/ajpregu.00044.2017. Epub 2017 Nov 8.
1123 Increased receptor activity-modifying protein 1 in the nervous system is sufficient to protect against autonomic dysregulation and hypertension.J Cereb Blood Flow Metab. 2019 Apr;39(4):690-703. doi: 10.1177/0271678X17751352. Epub 2018 Jan 3.
1124 Efficacy and Tolerability of Telmisartan/Amlodipine and Rosuvastatin Coadministration in Hypertensive Patients with Hyperlipidemia: A Phase III, Multicenter, Randomized, Double-blind Study.Clin Ther. 2019 Apr;41(4):728-741. doi: 10.1016/j.clinthera.2019.02.013. Epub 2019 Mar 21.
1125 Loss of reticulocalbin 2 lowers blood pressure and restrains ANG II-induced hypertension in vivo.Am J Physiol Renal Physiol. 2019 Jun 1;316(6):F1141-F1150. doi: 10.1152/ajprenal.00567.2018. Epub 2019 Apr 3.
1126 Mitogen-activated protein kinase p38 target regenerating islet-derived 3 expression is upregulated in cardiac inflammatory response in the rat heart.Physiol Rep. 2016 Oct;4(20):e12996. doi: 10.14814/phy2.12996. Epub 2016 Oct 24.
1127 Rho kinase activation in circulating leukocytes is related to hypertensive myocardial remodeling.Clin Sci (Lond). 2018 Aug 30;132(16):1837-1853. doi: 10.1042/CS20180312. Print 2018 Aug 31.
1128 Resistin Mediates Sex-Dependent Effects of Perivascular Adipose Tissue on Vascular Function in the Shrsp.Sci Rep. 2019 May 3;9(1):6897. doi: 10.1038/s41598-019-43326-z.
1129 Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1 Mechanisms.Hypertension. 2018 Aug;72(2):331-342. doi: 10.1161/HYPERTENSIONAHA.118.10845. Epub 2018 Jun 11.
1130 Antihyperglycemic agents as novel natriuretic therapies in diabetic kidney disease.Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1406-F1415. doi: 10.1152/ajprenal.00384.2017. Epub 2018 Aug 1.
1131 Identification of hypertension-susceptibility genes and pathways by a systemic multiple candidate gene approach: the millennium genome project for hypertension.Hypertens Res. 2008 Feb;31(2):203-12. doi: 10.1291/hypres.31.203.
1132 Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5.FASEB J. 2018 Apr;32(4):2021-2035. doi: 10.1096/fj.201700384RR. Epub 2018 Jan 5.
1133 PPAR and RhoBTB1 in hypertension.Curr Opin Nephrol Hypertens. 2020 Mar;29(2):161-170. doi: 10.1097/MNH.0000000000000579.
1134 Relaxin increases cardiac output and reduces systemic arterial load in hypertensive rats.Hypertension. 2005 Oct;46(4):745-50. doi: 10.1161/01.HYP.0000184230.52059.33. Epub 2005 Sep 19.
1135 Human recombinant relaxin-2 does not attenuate hypertension or renal injury but exacerbates vascular dysfunction in a female mouse model of SLE.Am J Physiol Heart Circ Physiol. 2019 Aug 1;317(2):H234-H242. doi: 10.1152/ajpheart.00174.2019. Epub 2019 May 24.
1136 Inhibition of human liver carboxylesterase (hCE1) by organophosphate ester flame retardants and plasticizers: implications for pharmacotherapy. Toxicol Sci. 2019 Jul 3. pii: kfz149.
1137 Role of Ryanodine Type 2 Receptors in Elementary Ca(2+) Signaling in Arteries and Vascular Adaptive Responses.J Am Heart Assoc. 2019 May 7;8(9):e010090. doi: 10.1161/JAHA.118.010090.
1138 Polymorphisms Within RYR3 Gene Are Associated With Risk and Age at Onset of Hypertension, Diabetes, and Alzheimer's Disease.Am J Hypertens. 2018 Jun 11;31(7):818-826. doi: 10.1093/ajh/hpy046.
1139 Gamma-glutamyltransferase, fatty liver index and hepatic insulin resistance are associated with incident hypertension in two longitudinal studies.J Hypertens. 2017 Mar;35(3):493-500. doi: 10.1097/HJH.0000000000001204.
1140 Genetic screening for pheochromocytoma: should SDHC gene analysis be included?.J Med Genet. 2007 Sep;44(9):586-7. doi: 10.1136/jmg.2007.051045. Epub 2007 Jun 8.
1141 What has changed in the prevalence of hypertension in dialyzed children during the last decade?.Ren Fail. 2017 Nov;39(1):283-289. doi: 10.1080/0886022X.2016.1260033. Epub 2016 Nov 24.
1142 Serum semaphorin 7A is associated with the risk of acute atherothrombotic stroke.J Cell Mol Med. 2019 Apr;23(4):2901-2906. doi: 10.1111/jcmm.14186. Epub 2019 Feb 7.
1143 Development of WNK signaling inhibitors as a new class of antihypertensive drugs.Bioorg Med Chem. 2017 Jul 15;25(14):3845-3852. doi: 10.1016/j.bmc.2017.05.034. Epub 2017 May 19.
1144 Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.Aging Cell. 2017 Jun;16(3):469-479. doi: 10.1111/acel.12583. Epub 2017 Mar 14.
1145 Plasminogen activator inhibitor-1 activity and the 4G/5G polymorphism are prospectively associated with blood pressure and hypertension status.J Hypertens. 2019 Dec;37(12):2361-2370. doi: 10.1097/HJH.0000000000002204.
1146 Clinical Implications of the Revised AAP Pediatric Hypertension Guidelines.Pediatrics. 2018 Aug;142(2):e20180245. doi: 10.1542/peds.2018-0245. Epub 2018 Jul 5.
1147 Structural insights into SETD3-mediated histidine methylation on -actin.Elife. 2019 Feb 20;8:e43676. doi: 10.7554/eLife.43676.
1148 The progression of comorbidity in IL-18 transgenic chronic obstructive pulmonary disease mice model.Biochem Biophys Res Commun. 2014 Mar 14;445(3):597-601. doi: 10.1016/j.bbrc.2014.02.052. Epub 2014 Feb 21.
1149 Blood Pressure and End-tidal Carbon Dioxide Ranges during Aneurysm Occlusion and Neurologic Outcome after an Aneurysmal Subarachnoid Hemorrhage.Anesthesiology. 2019 Jan;130(1):92-105. doi: 10.1097/ALN.0000000000002482.
1150 Hepatitis B and renal function: A matched study comparing non-hepatitis B, untreated, treated and cirrhotic hepatitis patients.Liver Int. 2019 Apr;39(4):655-666. doi: 10.1111/liv.14009. Epub 2018 Dec 18.
1151 Screening and management of risk factors for cardiovascular disease in HIV-positive patients attending an Australian urban sexual health clinic.Sex Health. 2017 Apr;14(2):198-200. doi: 10.1071/SH16106.
1152 Serine hydroxymethyltransferase 1 promoter hypermethylation increases the risk of essential hypertension.J Clin Lab Anal. 2019 Mar;33(3):e22712. doi: 10.1002/jcla.22712. Epub 2018 Nov 9.
1153 Haplotype of smoothelin gene associated with essential hypertension.Hereditas. 2012 Oct;149(5):178-85. doi: 10.1111/j.1601-5223.2012.02242.x. Epub 2012 Oct 18.
1154 Burst patterning of hypothalamic paraventricular nucleus-driven sympathetic nerve activity in ANG II-salt hypertension.Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H530-H541. doi: 10.1152/ajpheart.00560.2017. Epub 2017 Nov 22.
1155 Sorting nexin 1 loss results in D5 dopamine receptor dysfunction in human renal proximal tubule cells and hypertension in mice.J Biol Chem. 2013 Jan 4;288(1):152-63. doi: 10.1074/jbc.M112.428458. Epub 2012 Nov 14.
1156 The copper-zinc superoxide dismutase activity in selected diseases.Eur J Clin Invest. 2019 Jan;49(1):e13036. doi: 10.1111/eci.13036. Epub 2018 Nov 6.
1157 Genetic Variation in the Human SORBS1 Gene is Associated With Blood Pressure Regulation and Age at Onset of Hypertension: A SAPPHIRe Cohort Study.Medicine (Baltimore). 2016 Mar;95(10):e2970. doi: 10.1097/MD.0000000000002970.
1158 Association of two well-defined polymorphisms in leptin and leptin receptor genes with hypertension and circulating leptin: a meta-analysis.Arch Med Res. 2015 Jan;46(1):38-46. doi: 10.1016/j.arcmed.2014.11.012. Epub 2014 Dec 2.
1159 A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits.PLoS One. 2012;7(2):e31489. doi: 10.1371/journal.pone.0031489. Epub 2012 Feb 24.
1160 Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study.Int J Med Sci. 2016 Apr 10;13(5):325-9. doi: 10.7150/ijms.14849. eCollection 2016.
1161 Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in peripheral blood mononuclear cells in systemic sclerosis.J Rheumatol. 2004 Jan;31(1):88-95.
1162 MST3 is involved in ENaC-mediated hypertension.Am J Physiol Renal Physiol. 2019 Jul 1;317(7):F30-F42. doi: 10.1152/ajprenal.00455.2018. Epub 2019 Apr 10.
1163 Alpha-1 microglobulin as a potential therapeutic candidate for treatment of hypertension and oxidative stress in the STOX1 preeclampsia mouse model.Sci Rep. 2019 Jun 12;9(1):8561. doi: 10.1038/s41598-019-44639-9.
1164 Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure.JAMA Cardiol. 2019 Jan 1;4(1):25-33. doi: 10.1001/jamacardio.2018.3965.
1165 Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities.Transl Psychiatry. 2016 Aug 16;6(8):e870. doi: 10.1038/tp.2016.138.
1166 Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia.Nature. 2000 Jun 15;405(6788):797-800. doi: 10.1038/35015579.
1167 Prevalence of common disease-associated variants in Asian Indians.BMC Genet. 2008 Feb 4;9:13. doi: 10.1186/1471-2156-9-13.
1168 Late-onset pulmonary arterial hypertension in repaired D-transposition of great arteries: an uncommon complication.Pulm Circ. 2017 Apr-Jun;7(2):547-550. doi: 10.1177/2045893217699228. Epub 2017 May 30.
1169 Genome-wide association study of blood pressure and hypertension.Nat Genet. 2009 Jun;41(6):677-87. doi: 10.1038/ng.384. Epub 2009 May 10.
1170 Heterozygous CTNNB1 and TBX4 variants in a patient with abnormal lung growth, pulmonary hypertension, microcephaly, and spasticity.Clin Genet. 2019 Oct;96(4):366-370. doi: 10.1111/cge.13605. Epub 2019 Jul 22.
1171 Adjuvant strategies for prevention of glomerulosclerosis.Med Hypotheses. 2006;67(6):1277-96. doi: 10.1016/j.mehy.2004.11.048. Epub 2006 Jul 7.
1172 Polymorphisms of the TGFBRAP1 gene in relation to blood pressure variability and plasma TGF-1.Clin Exp Hypertens. 2015;37(5):420-5. doi: 10.3109/10641963.2015.1013113. Epub 2015 Apr 9.
1173 Thrombospondin-4 mediates cardiovascular remodelling in angiotensin II-induced hypertension.Cardiovasc Pathol. 2018 Jul-Aug;35:12-19. doi: 10.1016/j.carpath.2018.03.003. Epub 2018 Apr 7.
1174 MMP-9 and TIMP-1 in placenta of hypertensive disorder complicating pregnancy.Exp Ther Med. 2019 Jul;18(1):637-641. doi: 10.3892/etm.2019.7591. Epub 2019 May 17.
1175 TRIC-A channels in vascular smooth muscle contribute to blood pressure maintenance.Cell Metab. 2011 Aug 3;14(2):231-41. doi: 10.1016/j.cmet.2011.05.011.
1176 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.Hum Mol Genet. 2015 Feb 1;24(3):865-74. doi: 10.1093/hmg/ddu478. Epub 2014 Sep 23.
1177 Involvement of Ca(2+)-activated K(+) channel 3.1 in hypoxia-induced pulmonary arterial hypertension and therapeutic effects of TRAM-34 in rats.Biosci Rep. 2017 Jul 27;37(4):BSR20170763. doi: 10.1042/BSR20170763. Print 2017 Aug 31.
1178 The prevalence of type 2 diabetes and associated risk factors with generalized osteoarthritis: a retrospective study using ICD codes for clinical data repository system.Clin Rheumatol. 2019 Dec;38(12):3539-3547. doi: 10.1007/s10067-019-04712-0. Epub 2019 Aug 7.
1179 WNK4 enhances TRPV5-mediated calcium transport: potential role in hypercalciuria of familial hyperkalemic hypertension caused by gene mutation of WNK4.Am J Physiol Renal Physiol. 2007 Feb;292(2):F545-54. doi: 10.1152/ajprenal.00187.2006. Epub 2006 Oct 3.
1180 Contribution of the TTC21B gene to glomerular and cystic kidney diseases.Nephrol Dial Transplant. 2017 Jan 1;32(1):151-156. doi: 10.1093/ndt/gfv453.
1181 A W-test collapsing method for rare-variant association testing in exome sequencing data.Genet Epidemiol. 2016 Nov;40(7):591-596. doi: 10.1002/gepi.22000. Epub 2016 Aug 16.
1182 Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers (ACEI/ARB) are Associated with Improved Limb Salvage after Infrapopliteal Interventions for Critical Limb Ischemia.Ann Vasc Surg. 2020 Feb;63:275-286. doi: 10.1016/j.avsg.2019.08.093. Epub 2019 Oct 15.
1183 NALP3 inflammasome functional polymorphisms and gout susceptibility.Cell Cycle. 2009 Jan 1;8(1):27-30. doi: 10.4161/cc.8.1.7325. Epub 2009 Jan 31.
1184 The role of autoimmune reactivity induced by heat shock protein 70 in the pathogenesis of essential hypertension.Br J Pharmacol. 2019 Jun;176(12):1829-1838. doi: 10.1111/bph.14334. Epub 2018 May 22.
1185 Influence of glucose metabolism on cognitive function of patients with acute small-artery occlusion.J Biol Regul Homeost Agents. 2017 Jul-Sep;31(3):717-724.
1186 Proteomic analysis of aortic smooth muscle cell secretions reveals an association of myosin heavy chain 11 with abdominal aortic aneurysm.Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H1012-H1018. doi: 10.1152/ajpheart.00329.2018. Epub 2018 Jul 13.
1187 Rare variants in RNF213, a susceptibility gene for moyamoya disease, are found in patients with pulmonary hypertension and aggravate hypoxia-induced pulmonary hypertension in mice.Pulm Circ. 2018 Jul-Sep;8(3):2045894018778155. doi: 10.1177/2045894018778155. Epub 2018 May 2.