Details of the Drug Reposition

General Information of This Drug (ID: DM7BN0X)

• Drug Name: Esomeprazole (DM7BN0X)
• Synonyms: Esomeprazolum; Nexiam; Inexium paranova; Axagon (TN); Esomeprazole (INN); Esomeprazole [INN:BAN]; Esopral (TN); Inexium paranova (TN); Lucen (TN); Nexiam (TN); Nexium (TN); Sompraz (TN); Zoleri (TN); (S)-(-)-Omeprazole; (S)-Omeprazole; 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole; 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1-methyl-1H-benzimidazole
• Therapeutic Class: Antiulcer Agents
• Drug Type: Small molecular drug

Information on Drug Reposition of This Drug

6 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Peptic esophagitis	DISJSGBZ	N.A.	Approved	[1]
Laryngeal disorder	DISDKUQO	N.A.	Approved	[1]
Gastrinoma	DIS4IMNF	2C10.1	Approved	[1]
Cystic fibrosis	DIS2OK1Q	CA25	Approved	[1]
Peptic ulcer	DISL8XZI	DA61	Approved	[2]
Nausea	DIS50TOO	MD90	Approved	[1]

1 Discontinued in Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Erosive esophagitis	DIST4BF8	DA25.0	Discontinued in Phase 2	[3]

1 Discontinued in Phase 1 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Gastroesophageal reflux disease	DISQ8G5S	DA22.Z	Discontinued in Phase 1	[4]

References

• [1] Esomeprazole FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5488).
• [3] Capecitabine, Oxaliplatin, and Gefitinib in Treating Patients With Metastatic Colorectal Cancer
• [4] Bevacizumab, Paclitaxel, Carboplatin, and Radiation Therapy to the Chest in Treating Patients With Locally Advanced Non-Small Cell Lung Cancer