Details of the Drug Reposition

General Information of This Drug (ID: DMAE84F)

• Drug Name: Alclometasone (DMAE84F)
• Synonyms: Aclometasone; Aclovate (TN); Alclometasone (INN); Alclometasone [INN:BAN]; (7R,8S,9S,10R,11S,13S,14S,16R,17R)-7-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one; (7alpha,11beta,16alpha)-7-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 7alpha-Chloro-16alpha-methylprednisolone
• Therapeutic Class: Antiinflammatory Agents
• Drug Type: Small molecular drug

Information on Drug Reposition of This Drug

4 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Primary cutaneous T-cell lymphoma	DIS35WVW	N.A.	Approved	[1]
Granuloma annulare	DISMOUMI	N.A.	Approved	[1]
Exanthem	DISAFOQN	N.A.	Approved	[1]
Inflammation	DISJUQ5T	1A00-CA43.1	Approved	[2]

3 Discontinued in Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Atopic dermatitis	DISTCP41	EA80	Discontinued in Phase 2	[3]
Seborrhoeic dermatitis	DISNWVJU	EA81	Discontinued in Phase 2	[4]
Contact dermatitis	DISQ3AU0	EK0Z	Discontinued in Phase 2	[5]

References

• [1] Alclometasone FDA Label
• [2] Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
• [3] Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders
• [4] A Safety and Efficacy Study of JNJ26489112 in Patients With Treatment-Resistant Major Depressive Disorder
• [5] Ketoconazole With or Without Alendronate Sodium in Treating Patients With Metastatic Prostate Cancer