Details of the Drug Reposition

General Information of This Drug (ID: DMUL45H)

Drug Name
Naltrexone   DMUL45H
Synonyms
Depotrex; Naltrel; Vivitrex; Vivitrol; Naltrexone Depot; IBS therapy, Pain Therapeutics; Irritable bowel syndrome therapy, Pain Therapeutics; PTI-901; XR-NTX; Naltrexone (sustained release), DAS; Naltrexone (sustained release), elbion; Naltrexone depot (injectable suspension), DrugAbuse Sciences; Naltrexone depot (injectable suspension), elbion; Opioid antagonists (irritable bowel syndrome), Pain Therapeutics; Naltrexone (low-dose), Pain Therapeutics; Naltrexone (polymer microcapsule depot, opioid addiction/alcohol dependency), Biotek; Naltrexone (transdermal, alcohol/opioid dependence), Syntropharma; Naltrexone (once-monthly controlled-release, Medisorb), Alkermes
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
6 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Obesity DIS47Y1K 5B81 Approved [1]
Alcohol dependence DIS4ZSCO 6C40.2 Approved [1]
Gastroparesis DISDW0SR DA41.00 Approved [1]
Crohn disease DIS2C5Q8 DD70 Approved [1]
Ulcerative colitis DIS8K27O DD71 Approved [1]
Inflammatory bowel disease DISGN23E DD72 Approved [1]
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⏷ Show the Full List of 6 Indications(s)
1 Phase 4 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Human immunodeficiency virus infection DISRNAI4 1C62 Phase 4 [2]
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1 Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Coronavirus Disease 2019 (COVID-19) DISM7GNX 1D6Y Phase 2 [3]
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1 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Chronic pain DISXRS8Y MG30 Investigative [1]
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References

1 Naltrexone FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1639).
3 ClinicalTrials.gov (NCT04365985) Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19. U.S. National Institutes of Health.