General Information of Disease (ID: DIS47Y1K)

Disease Name Obesity
Synonyms obesity; obesity disease
Disease Class 5B80-5B81: Obesity
Definition A disorder involving an excessive amount of body fat.|Obesity is a complex disease that may involve multiple environmental and genetic causes. See the subclass monogenic disease for genetic subtypes
Disease Hierarchy
DISGAJIG: Overnutrition
DISWD40R: Disease
DIS47Y1K: Obesity
ICD Code
ICD-11
ICD-11: 5B81
ICD-10
ICD-10: E66
Disease Identifiers
MONDO ID
MONDO_0011122
MESH ID
D009765
UMLS CUI
C0028754
OMIM ID
601665
MedGen ID
18127
HPO ID
HP:0001513
Orphanet ID
521399
SNOMED CT ID
414915002

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 25 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Amfepramone DM9YSNQ Approved Small molecular drug [1]
Amphetamine DMSZQAK Approved Small molecular drug [2]
Anastrozole DMNP60F Approved Small molecular drug [3]
Benzphetamine DMIJATC Approved Small molecular drug [4]
Bupropion DM5PCS7 Approved Small molecular drug [5]
Fenofibrate DMFKXDY Approved Small molecular drug [6]
Liraglutide DM3FXPS Approved Small molecular drug [7]
Lorcaserin DMG6OYJ Approved Small molecular drug [8]
Mazindol DMZ36RN Approved Small molecular drug [9]
Methamphetamine DMPM4SK Approved Small molecular drug [10]
Methylnaltrexone bromide DMZTGN2 Approved Small molecular drug [11]
Metoprolol DMOJ0V6 Approved Small molecular drug [12]
Naltrexone DMUL45H Approved Small molecular drug [13]
Orlistat DMRJSP8 Approved Small molecular drug [4]
Phendimetrazine DM6TS1N Approved Small molecular drug [4]
Phenmetrazine DMXYTN9 Approved Small molecular drug [14]
Phentermine DMG60XN Approved Small molecular drug [15]
Pioglitazone DMKJ485 Approved Small molecular drug [16]
Propylhexedrine DMTBW2O Approved Small molecular drug [4]
Quercetin DM3NC4M Approved Small molecular drug [17]
Setmelanotide DMPVRN9 Approved NA [18]
Sibutramine DMFJTDI Approved Small molecular drug [19]
SR141716A DMCO5JZ Approved Small molecular drug [4]
Topiramate DM82Z30 Approved Small molecular drug [20]
Trihexyphenidyl DMB19L8 Approved Small molecular drug [16]
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⏷ Show the Full List of 25 Drug(s)
This Disease is Treated as An Indication in 71 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
ALS-L1023 DMS6QGO Phase 3 NA [21]
Amitifadine DMS1X67 Phase 3 Small molecular drug [22]
ATX-101 DM64WYC Phase 3 NA [23]
Beloranib DM71CK8 Phase 3 Small molecular drug [24]
Cetilistat DMWAHTN Phase 3 Small molecular drug [25]
Fenfluramine DM0762O Phase 3 Small molecular drug [26]
GMA102 DMQIE7U Phase 3 Antibody [27]
GMA105 DM2XSG0 Phase 3 Antibody [28]
Orforglipron DMC50VB Phase 3 Small molecule [29]
Retatrutide DM8WU0Q Phase 3 Peptide [30]
Second generation therapeutics DM2LCO4 Phase 3 Small molecular drug [31]
Tebipenem DMVSX6O Phase 3 Small molecular drug [11]
MBX-8025 DMNTCV4 Phase 2/3 Small molecular drug [32]
AMG 133 DMSRCIS Phase 2 Antibody peptide conjugate [33]
ARD-101 DMAB3EL Phase 2 NA [34]
ATHX-105 DM6ABD9 Phase 2 NA [35]
AZ-40140 DM9LKYP Phase 2 NA [11]
CL-316,243 DMXH1KC Phase 2 Small molecular drug [36]
CP-741952 DMHJ7IG Phase 2 NA [37]
GSK2890457 DMT5YK7 Phase 2 NA [38]
HTI-101 DMURXMJ Phase 2 NA [39]
ISIS-FGFR4 DMNVZDT Phase 2 Antisense drug [40]
JNJ-64565111 DMVSUH1 Phase 2 NA [41]
LY-362884 DMD09CT Phase 2 NA [11]
LY-377604 DMZCU7I Phase 2 Small molecular drug [42]
LY3437943 DMN37M6 Phase 2 Peptide [43]
MB-12066 DMRSN2C Phase 2 NA [44]
MBL949 DM16I0A Phase 2 NA [45]
MLR-1023 DM4RNOT Phase 2 Small molecular drug [46]
N-5984 DMUK6HC Phase 2 Small molecular drug [11]
OBE-101 DMJIBSG Phase 2 NA [47]
Oleoyl-estrone DM0RA8F Phase 2 Small molecular drug [48]
Peptide YY 3-36 DMNU48O Phase 2 NA [49]
PF-07081532 DM9WHMF Phase 2 Small molecule [50]
PRX00933 DM1JNDV Phase 2 NA [51]
SR-147778 DMNAECP Phase 2 Small molecular drug [52]
TTP435 DMMNTOW Phase 2 NA [53]
Yso1 DM8RR54 Phase 2 Small molecule [54]
PP-1420 DMQOW0H Phase 1/2 NA [55]
AMG 786 DMNQM73 Phase 1 Small molecule [56]
AZD1979 DMQ1OX4 Phase 1 NA [57]
AZD5658 DMV6DF3 Phase 1 NA [58]
AZD6234 DM7KBD0 Phase 1 Peptide [59]
AZD7687 DMS9I6A Phase 1 Small molecular drug [60]
AZD8329 DMTD57A Phase 1 Small molecular drug [61]
BMS-830216 DMCW71N Phase 1 NA [62]
BVT-74316 DMEP321 Phase 1 Small molecular drug [63]
CIN-109 DMZTPX3 Phase 1 NA [64]
CT-388 DMWHBE5 Phase 1 NA [65]
DD01 DM0JKZ6 Phase 1 Peptide [66]
ERX-1000 DMO18P9 Phase 1 NA [67]
G530L DMJ80WL Phase 1 NA [68]
GDC-0152 DM1B3UM Phase 1 Small molecular drug [69]
GSK1521498 DM2L7TH Phase 1 Small molecular drug [70]
GSK2374697 DMMLSZL Phase 1 NA [71]
KD3010 DMNFDYE Phase 1 NA [72]
L-796568 DMXKO1L Phase 1 Small molecular drug [73]
LA-GDF15 DMNK2UT Phase 1 NA [74]
LY 3541105 DMJ1X85 Phase 1 Monoclonal antibody [75]
LY3841136 DMLT2EB Phase 1 NA [76]
NO-13065 DM7LGYI Phase 1 NA [77]
PegCNTF DMW7VGZ Phase 1 Small molecular drug [11]
Pemvidutide DMVOG8A Phase 1 Small molecule [78]
Prohibitin targeting peptide-1 DMK0WUP Phase 1 NA [79]
PRX-07034 DM5TLAP Phase 1 Small molecular drug [80]
PYY 1875 DMEB7D6 Phase 1 NA [81]
S-309309 DMPQQ9B Phase 1 Small molecule [82]
TM38837 DMCFGD4 Phase 1 Small molecular drug [83]
Trodusquemine DMQ7UN6 Phase 1 Small molecular drug [84]
ZP2929 DMRVDUM Phase 1 NA [85]
ZY01 DMSLPTO Phase 1 NA [86]
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⏷ Show the Full List of 71 Drug(s)
This Disease is Treated as An Indication in 149 Patented Agent(s)
Drug Name Drug ID Highest Status Drug Type REF
1,2,3-triazole derivative 1 DMKHF39 Patented Small molecular drug [87]
1,2,3-triazole derivative 2 DMFR23C Patented Small molecular drug [87]
1,2,4,5-tetra-substituted imidazole derivative 1 DMLAYG7 Patented Small molecular drug [87]
1,2,4,5-tetra-substituted imidazole derivative 2 DMMCYI5 Patented Small molecular drug [87]
1,2,4-tri-substituted imidazoline derivative 1 DMMNVZ5 Patented Small molecular drug [87]
1,2,4-triazole derivative 1 DME8MN1 Patented Small molecular drug [87]
1,2,4-triazole derivative 2 DM91Z8B Patented Small molecular drug [87]
1,5-diphenylpyrrolidin-2-one derivative 1 DMZY3HC Patented Small molecular drug [87]
1,5-diphenylpyrrolidin-2-one derivative 2 DMBR2Y9 Patented Small molecular drug [87]
4-methyl-4,5-dihydro-1H-pyrazole-3-carboxamide derivative 1 DMNTOZV Patented Small molecular drug [87]
Amide derivative 1 DMO64LA Patented Small molecular drug [87]
Aminoazetidine derivative 1 DMNI0M1 Patented Small molecular drug [87]
Aminoazetidine derivative 2 DMHSNA5 Patented Small molecular drug [87]
Aminoazetidine derivative 3 DMOQHA9 Patented Small molecular drug [87]
Aminoazetidine derivative 4 DM50E4Y Patented Small molecular drug [87]
Aminoazetidine derivative 5 DMYPD4Z Patented Small molecular drug [87]
Aminoazetidine derivative 7 DM3LNQG Patented Small molecular drug [87]
Aminoazetidine derivative 8 DMLOIHD Patented Small molecular drug [87]
Aminoazetidine derivative 9 DMUASHT Patented Small molecular drug [87]
Azetidine derivative 1 DMXEFUD Patented Small molecular drug [87]
Azetidine derivative 3 DMIKSVG Patented Small molecular drug [87]
Azetidine derivative 4 DMXL2V9 Patented Small molecular drug [87]
Azetidine-1-carboxamide derivative 1 DMZX8Y0 Patented Small molecular drug [87]
Azetidine-1-carboxamide derivative 2 DMONQ4L Patented Small molecular drug [87]
Azetidine-1-carboxamide derivative 3 DM2UGK3 Patented Small molecular drug [87]
Benzimidazole derivative 1 DML8W16 Patented Small molecular drug [87]
Benzimidazole derivative 2 DM4ZUDY Patented Small molecular drug [87]
Carboxamide derivative 1 DM5GEBH Patented Small molecular drug [87]
Diaryl morpholine derivative 1 DMIQOY7 Patented Small molecular drug [87]
Diaryl piperazine derivative 1 DMERQ7V Patented Small molecular drug [87]
Diaryl piperazine derivative 2 DMDOB20 Patented Small molecular drug [87]
Diphenyl purine derivative 1 DM2DYMS Patented Small molecular drug [87]
Diphenyl purine derivative 2 DMG8MCJ Patented Small molecular drug [87]
Diphenyl purine derivative 3 DMY5CFW Patented Small molecular drug [87]
Diphenyl purine derivative 4 DMP3JF4 Patented Small molecular drug [87]
Diphenyl purine derivative 5 DMC2T4H Patented Small molecular drug [87]
Furopyridine derivative 1 DM2QXVW Patented Small molecular drug [87]
Furopyridine derivative 2 DMEU3J9 Patented Small molecular drug [87]
Heterocyclic-substituted 3-alkyl azetidine derivative 1 DMJEX3D Patented Small molecular drug [87]
Heterocyclic-substituted 3-alkyl azetidine derivative 2 DMEX7PV Patented Small molecular drug [87]
Heterocyclic-substituted 3-alkyl azetidine derivative 3 DMO1Y30 Patented Small molecular drug [87]
Hydrazide derivative 1 DMUA740 Patented Small molecular drug [87]
Imidazole derivative 1 DM14KHX Patented Small molecular drug [87]
Imidazole derivative 2 DM8GCVO Patented Small molecular drug [87]
Imidazole derivative 3 DMV1ER2 Patented Small molecular drug [87]
Imidazole derivative 4 DMPGMX2 Patented Small molecular drug [87]
Imidazole derivative 5 DMVSXUM Patented Small molecular drug [87]
Imidazole derivative 6 DMOXHZJ Patented Small molecular drug [87]
Imidazole derivative 7 DMLPQ7E Patented Small molecular drug [87]
Imidazolidine-2,4-dione derivative 1 DMUFSQ2 Patented Small molecular drug [87]
Imidazolidine-2,4-dione derivative 2 DMVMD2O Patented Small molecular drug [87]
N-(arylalkyl)-1H-indole-2-sulfonic acid amide derivative 1 DM6TYM0 Patented Small molecular drug [87]
N-(arylalkyl)-1H-indole-2-sulfonic acid amide derivative 2 DM2MPN0 Patented Small molecular drug [87]
N-phenyl-5-phenyl-pyrazolin-3-yl amide derivative 1 DM9A8L5 Patented Small molecular drug [87]
N-phenyl-5-phenyl-pyrazolin-3-yl amide derivative 2 DM8T2LV Patented Small molecular drug [87]
N-phenyl-5-phenyl-pyrazolin-3-yl amide derivative 3 DMEH0RC Patented Small molecular drug [87]
Piperazine derivative 1 DMJ7F1Q Patented Small molecular drug [87]
Piperazine derivative 2 DM4JZ2T Patented Small molecular drug [87]
PMID25470667-Compound-GO-CoA-Tat DME40TS Patented Small molecular drug [88]
PMID26161824-Compound-68 DMF9C4I Patented Small molecular drug [87]
PMID26161824-Compound-69 DMKOSN5 Patented Small molecular drug [87]
Purine derivative 1 DMB65Z4 Patented Small molecular drug [87]
Purine derivative 2 DMNRG0P Patented Small molecular drug [87]
Purine derivative 3 DMPI2S9 Patented Small molecular drug [87]
Pyrano[2,3-b]pyridine derivative 1 DMMVG2O Patented Small molecular drug [87]
Pyrano[2,3-b]pyridine derivative 2 DMOJ8P1 Patented Small molecular drug [87]
Pyrazole derivative 1 DM3R9PL Patented Small molecular drug [87]
Pyrazole derivative 11 DMH7PGU Patented Small molecular drug [87]
Pyrazole derivative 12 DM7LFNG Patented Small molecular drug [87]
Pyrazole derivative 13 DM5S3L0 Patented Small molecular drug [87]
Pyrazole derivative 14 DMEDXW9 Patented Small molecular drug [87]
Pyrazole derivative 15 DMJCX8M Patented Small molecular drug [87]
Pyrazole derivative 16 DM5A8F3 Patented Small molecular drug [87]
Pyrazole derivative 17 DM7F9V4 Patented Small molecular drug [87]
Pyrazole derivative 18 DMVZ8KD Patented Small molecular drug [87]
Pyrazole derivative 19 DMM7OR3 Patented Small molecular drug [87]
Pyrazole derivative 2 DMIS97T Patented Small molecular drug [87]
Pyrazole derivative 20 DM2HO1S Patented Small molecular drug [87]
Pyrazole derivative 21 DMUPNHA Patented Small molecular drug [87]
Pyrazole derivative 22 DMCS08K Patented Small molecular drug [87]
Pyrazole derivative 23 DMH2LFS Patented Small molecular drug [87]
Pyrazole derivative 24 DMVX2D0 Patented Small molecular drug [87]
Pyrazole derivative 25 DMM2RYG Patented Small molecular drug [87]
Pyrazole derivative 26 DMX92ZK Patented Small molecular drug [87]
Pyrazole derivative 27 DMDB5FH Patented Small molecular drug [87]
Pyrazole derivative 28 DMYEFW1 Patented Small molecular drug [87]
Pyrazole derivative 29 DM7DTYS Patented Small molecular drug [87]
Pyrazole derivative 3 DMX2NQW Patented Small molecular drug [87]
Pyrazole derivative 30 DMT1DJP Patented Small molecular drug [87]
Pyrazole derivative 31 DMDTQCG Patented Small molecular drug [87]
Pyrazole derivative 32 DMU59IJ Patented Small molecular drug [87]
Pyrazole derivative 33 DMUNLK8 Patented Small molecular drug [87]
Pyrazole derivative 34 DMRH2EJ Patented Small molecular drug [87]
Pyrazole derivative 35 DM6KROX Patented Small molecular drug [87]
Pyrazole derivative 36 DMSDVI1 Patented Small molecular drug [87]
Pyrazole derivative 37 DMZJ5FN Patented Small molecular drug [87]
Pyrazole derivative 38 DMPVDSC Patented Small molecular drug [87]
Pyrazole derivative 39 DMMGWKE Patented Small molecular drug [87]
Pyrazole derivative 4 DM2DK1E Patented Small molecular drug [87]
Pyrazole derivative 40 DM7CMV6 Patented Small molecular drug [87]
Pyrazole derivative 5 DMDGSKH Patented Small molecular drug [87]
Pyrazole derivative 53 DMMIOZ5 Patented Small molecular drug [87]
Pyrazole derivative 54 DM9PNTF Patented Small molecular drug [87]
Pyrazole derivative 57 DMZ3J78 Patented Small molecular drug [87]
Pyrazole derivative 58 DMZIOW0 Patented Small molecular drug [87]
Pyrazole derivative 59 DMXZC8K Patented Small molecular drug [87]
Pyrazole derivative 6 DMIDN6T Patented Small molecular drug [87]
Pyrazole derivative 60 DMQ08BM Patented Small molecular drug [87]
Pyrazole derivative 7 DMYKU0T Patented Small molecular drug [87]
Pyrazole derivative 8 DMMRTAL Patented Small molecular drug [87]
Pyrazoline derivative 1 DMGS2ET Patented Small molecular drug [87]
Pyrazoline derivative 10 DMCZORA Patented Small molecular drug [87]
Pyrazoline derivative 11 DMAB3YG Patented Small molecular drug [87]
Pyrazoline derivative 2 DMOA8E4 Patented Small molecular drug [87]
Pyrazoline derivative 3 DMGH0LQ Patented Small molecular drug [87]
Pyrazoline derivative 4 DMRT7I8 Patented Small molecular drug [87]
Pyrazoline derivative 5 DMEGS9U Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 1 DM0FPMV Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 10 DM07GEK Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 11 DM0O4WR Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 12 DMMLDUI Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 13 DMR5O7T Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 2 DMO3MJ7 Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 3 DMHTV47 Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 4 DMCAVF0 Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 5 DM3UBG2 Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 6 DM5E1KS Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 7 DMFUSPR Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 8 DMTQNYZ Patented Small molecular drug [87]
Pyrazolo[1,5-a]pyrimidine derivative 9 DMXAW2S Patented Small molecular drug [87]
Pyridotriazolopyrimidine derivative 1 DM71UYI Patented Small molecular drug [87]
Pyridotriazolopyrimidine derivative 2 DM0VOY9 Patented Small molecular drug [87]
Pyridotriazolopyrimidine derivative 3 DMYVCTD Patented Small molecular drug [87]
Pyrido[2,3-d]pyrimidine derivative 1 DMHZLSO Patented Small molecular drug [87]
Pyrido[2,3-d]pyrimidine derivative 2 DMSM53I Patented Small molecular drug [87]
Pyrrole derivative 1 DM0RC1Z Patented Small molecular drug [87]
Pyrrole derivative 2 DMMNKFX Patented Small molecular drug [87]
Pyrrole derivative 3 DMFV64B Patented Small molecular drug [87]
Pyrrole derivative 4 DMQDL43 Patented Small molecular drug [87]
Pyrrole derivative 5 DMJUMC6 Patented Small molecular drug [87]
Pyrrole derivative 6 DM875RE Patented Small molecular drug [87]
Sulfonamide derivative 1 DMTX21L Patented Small molecular drug [87]
Sulfonylated piperazine derivative 1 DMCO8JD Patented Small molecular drug [87]
Sulfonylated piperazine derivative 2 DMZYPV3 Patented Small molecular drug [87]
Sulfonylated piperazine derivative 3 DMOJAZ9 Patented Small molecular drug [87]
Sulfonylated piperazine derivative 4 DMZW2XP Patented Small molecular drug [87]
Sulfonylated piperazine derivative 5 DM65NBS Patented Small molecular drug [87]
Tetra-hydro-1H-1,2,6-triazaazulene derivative 1 DMUXNKG Patented Small molecular drug [87]
Tetra-hydro-1H-1,2,6-triazaazulene derivative 2 DMVTZ6S Patented Small molecular drug [87]
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⏷ Show the Full List of 149 Drug(s)
This Disease is Treated as An Indication in 50 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Dexfenfluramine DMJ7YDS Withdrawn from market Small molecular drug [16]
Phenylpropanolamine DMTFK3O Withdrawn from market Small molecular drug [1]
Amibegron DMPS14M Discontinued in Phase 3 Small molecular drug [89]
Axokine DMT5O8I Discontinued in Phase 3 NA [90]
CGP71683A DMRYC08 Discontinued in Phase 3 Small molecular drug [91]
CP-945598 DMOU173 Discontinued in Phase 3 Small molecular drug [11]
KI-0805 DM81T1V Discontinued in Phase 3 NA [92]
Taranabant DM5G9W0 Discontinued in Phase 3 Small molecular drug [16]
AC 137-164594 DMQOX62 Discontinued in Phase 2 NA [93]
AOD-9604 DMGDPSI Discontinued in Phase 2 Small molecular drug [11]
AZD2207 DM1TDWI Discontinued in Phase 2 Small molecular drug [94]
CE-326597 DMXO49B Discontinued in Phase 2 Small molecular drug [95]
Davalintide DM9S3R8 Discontinued in Phase 2 NA [96]
GI 181771 DMIUFS4 Discontinued in Phase 2 Small molecular drug [97]
GT-389255 DMLFCNY Discontinued in Phase 2 NA [98]
HMR-1426 DMIJSB3 Discontinued in Phase 2 NA [99]
Lintitript DMS5X94 Discontinued in Phase 2 Small molecular drug [100]
PYY3-36 DMTGFV6 Discontinued in Phase 2 NA [101]
SLV319 DM0GKHX Discontinued in Phase 2 Small molecular drug [102]
TM30338 DMXNQLU Discontinued in Phase 2 NA [103]
Velneperit DMROSHN Discontinued in Phase 2 Small molecular drug [104]
CYT-009-GhrQb DMCWRYS Discontinued in Phase 1/2 Small molecular drug [11]
NN-9161 DM8ZAB6 Discontinued in Phase 1/2 NA [105]
AC-162352 DME98LV Discontinued in Phase 1 NA [11]
AMG 076 DMIKQ40 Discontinued in Phase 1 Small molecular drug [106]
Axovan-3 DM1JN6A Discontinued in Phase 1 NA [107]
AZD1175 DM65MUI Discontinued in Phase 1 NA [108]
JTT-553 DMI7Z1Y Discontinued in Phase 1 NA [109]
MX-68 DML58C4 Discontinued in Phase 1 Small molecular drug [110]
NGD-4715 DMXDLUH Discontinued in Phase 1 Small molecular drug [111]
PF-3932295 DMZ888A Discontinued in Phase 1 NA [112]
PF-431499 DMTPSKQ Discontinued in Phase 1 NA [113]
PF-514273 DMS7M0U Discontinued in Phase 1 Small molecular drug [114]
R-1065 DMHPV1D Discontinued in Phase 1 NA [115]
S-234462 DM80P4U Discontinued in Phase 1 NA [116]
SR-146131 DML7KCO Discontinued in Phase 1 Small molecular drug [117]
SSR-125180 DMSOBW2 Discontinued in Phase 1 NA [118]
SX-013 DM6E8NQ Discontinued in Phase 1 NA [119]
UCL-2000; butabindide DML51D0 Discontinued in Phase 1 NA [120]
A-68552 DM1BDHY Terminated Small molecular drug [126]
A-71623 DMKZNTY Terminated Small molecular drug [127]
A-798 DMXWG6Z Terminated NA [128]
ALB-127158(a) DMWNMYS Terminated NA [129]
AZM-131 DMLCSRF Terminated NA [130]
BRL 26830A DMGX0E1 Terminated Small molecular drug [131]
BVT-24834 DMHLUFN Terminated NA [132]
MPV-1743 DMQKDX4 Terminated NA [133]
NLC-002 DM5YF6T Terminated NA [134]
RWJ-49815 DMUGZMO Terminated Small molecular drug [107]
SNX-024 DMFU90V Terminated NA [135]
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⏷ Show the Full List of 50 Drug(s)
This Disease is Treated as An Indication in 31 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
A-71378 DMZ4HMP Preclinical Small molecular drug [121]
A-74498 DMAK6H3 Preclinical NA [11]
AR-R-1589 DMMD8VY Preclinical NA [11]
BMS-192548 DMHAWBR Preclinical NA [11]
CB1 antagonist, Bayer DM53JW0 Preclinical Small molecular drug [11]
CIN-110 DMYMZQW Preclinical NA [64]
CIN-209 DMBK5CQ Preclinical NA [64]
CL-314698 DM6HADZ Preclinical NA [11]
CP-114271 DMATUKO Preclinical NA [11]
EP-01492 DM2K51E Preclinical Small molecular drug [11]
FPL-14294 DMUHVEA Preclinical Small molecular drug [11]
FR-79620 DMXR287 Preclinical Small molecular drug [11]
GCR-1087 DMFW0H9 Preclinical NA [11]
GG-8573 DMFQI38 Preclinical NA [11]
GI-264879A DM25N8B Preclinical Small molecular drug [11]
GNTI DMTJRLU Preclinical Small molecular drug [11]
GW-594884A DMHUD27 Preclinical NA [11]
IDDB-41331 DMIYSD4 Preclinical NA [11]
IDDBCP-150101 DMQ3BXV Preclinical NA [11]
JD-5037 DMTGI64 Preclinical NA [122]
L-742791 DMK3TXY Preclinical Small molecular drug [123]
L-751250 DMOERXK Preclinical Small molecular drug [11]
LY-25582 DM2N637 Preclinical Small molecular drug [11]
Melanotetan II DMYK8MV Preclinical Small molecular drug [11]
NPY5RA-972 DMXUCSN Preclinical Small molecular drug [11]
PD-160170 DMB9Z4C Preclinical Small molecular drug [11]
PD-170292 DMEOVDQ Preclinical Small molecular drug [11]
Ro-27-3225 DMF3YQZ Preclinical Small molecular drug [11]
SNAP-7941 DM5KE4R Preclinical Small molecular drug [124]
T-226293 DM7Y4GT Preclinical Small molecular drug [11]
T-226296 DMJ6P9U Preclinical Small molecular drug [125]
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⏷ Show the Full List of 31 Drug(s)
This Disease is Treated as An Indication in 43 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
A-331440 DMPU3QR Investigative Small molecular drug [136]
AC-163954 DM41CSR Investigative NA [137]
Adiptin DMIQWQH Investigative NA [137]
AMR-SIX-1 DM7WTKJ Investigative NA [138]
ANG-2004 DMK1IMC Investigative NA [139]
Aom-0977 DMXKVRV Investigative NA [137]
ATH-90879 DMSNBMQ Investigative NA [140]
BMS-812204 DM1HBF5 Investigative NA [141]
BVT 933 DM8N7BA Investigative NA [16]
C75 DMHGX1N Investigative Small molecular drug [142]
Ciproxifan DM9N8WM Investigative Small molecular drug [143]
CO-18 DMT7X73 Investigative NA [137]
CSC-500297 DM6K123 Investigative NA [144]
Dry-powder peptide YY(3-36) DMSZ9JY Investigative NA [137]
EDP-21 DMMN0GO Investigative NA [139]
FAS-115 DMI1Z58 Investigative NA [137]
FAS-89B DM8TD75 Investigative NA [137]
JD-0100 DMLBX3Q Investigative NA [145]
JNJ-1136 DM45ZNE Investigative NA [137]
KDT-600 DMFV0CH Investigative NA [137]
KI-0907 DM8QH84 Investigative NA [137]
Long-acting oxyntomodulin DMLO4OT Investigative NA [137]
MK-5596 DMLWMZ4 Investigative Small molecular drug [141]
MK-7725 DM3EP59 Investigative Small molecular drug [146]
MKC-180 DMIGHUQ Investigative NA [137]
MOD-1002 DM1C4PL Investigative NA [137]
NDM-10107 DMPD5CI Investigative NA [137]
NOX-B11 DMFW8O5 Investigative NA [147]
Oxymera DMFNECH Investigative NA [137]
PEGylated leptin DMZ01PS Investigative NA [139]
PMI-008 DMHX704 Investigative NA [148]
PSN-842 DMOWMV9 Investigative NA [137]
PYN-22 DM065DZ Investigative NA [137]
RO-6036 DM6B8ER Investigative NA [137]
RP-1000 DMKARHF Investigative NA [137]
S-100 DM209OB Investigative Small molecular drug [137]
SJ-BRV DM0GBHI Investigative NA [137]
TG-1022 DMSG0TL Investigative NA [149]
TPI-1361-17 DMW2FTP Investigative Small molecular drug [150]
UGP-281 DMCYXLU Investigative NA [137]
Weight regulating human endocrine peptide DMTQ8UP Investigative NA [137]
WIN-902A DM08XK2 Investigative NA [137]
YD-501 DMWAMS1 Investigative NA [137]
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⏷ Show the Full List of 43 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 719 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ACACB TTY84UG Limited Biomarker [154]
ADAM17 TT6AZXG Limited Genetic Variation [155]
AHR TT037IE Limited Biomarker [156]
AKR1B1 TTFBNVI Limited Altered Expression [157]
APOL1 TTDB8PW Limited Biomarker [158]
BACE1 TTJUNZF Limited Altered Expression [159]
BLVRA TTJBPN3 Limited Biomarker [160]
C5AR1 TTHXFA1 Limited Therapeutic [161]
CALCA TTVSFJW Limited Biomarker [162]
CCR2 TTFZYTO Limited Biomarker [163]
CD200 TT0BE68 Limited Genetic Variation [164]
CD69 TTPQE9F Limited Biomarker [165]
CES1 TTMF541 Limited Genetic Variation [166]
CFH TTUW6OP Limited Genetic Variation [167]
CPS1 TT42M75 Limited Biomarker [168]
CSE1L TTTRULD Limited Genetic Variation [169]
CTSC TT4H0V2 Limited Biomarker [170]
CX3CR1 TT2T98G Limited Biomarker [171]
CYBB TT5T8MR Limited Altered Expression [172]
DMD TTWLFXU Limited Biomarker [173]
EBP TT4VQZX Limited Genetic Variation [174]
EIF4EBP1 TTKGEBL Limited Genetic Variation [175]
ESRRG TT9ZRHB Limited Altered Expression [176]
FFAR2 TT0FYAN Limited Altered Expression [177]
FGG TTR31L7 Limited Biomarker [178]
FSHB TT13GFV Limited Biomarker [179]
FSHR TTZFDBT Limited Altered Expression [180]
G6PD TTKN8W0 Limited Biomarker [181]
GCH1 TTLSWP6 Limited Biomarker [182]
GFRAL TTE61UB Limited Biomarker [183]
GGT1 TTZVT7O Limited Biomarker [184]
GJA5 TTFQKZ7 Limited Biomarker [185]
GPR12 TT3IPW2 Limited Biomarker [186]
GSK3A TTQWAU1 Limited Posttranslational Modification [187]
HCAR2 TTWNV8U Limited Biomarker [188]
HDAC11 TT8K17W Limited Biomarker [189]
HDAC3 TT4YWTO Limited Biomarker [190]
HMGCS1 TTQF4TK Limited Biomarker [191]
HOXA5 TTXSVQP Limited Biomarker [192]
HTR1B TTK8CXU Limited Biomarker [193]
IGFBP2 TTU4QSN Limited Posttranslational Modification [194]
IL1R1 TTWOTEA Limited Biomarker [195]
KCNK3 TTGR91N Limited Altered Expression [196]
KCNMA1 TTE87WJ Limited Biomarker [197]
KITLG TTDJ51N Limited Biomarker [198]
LAPTM4B TTEJQT0 Limited Biomarker [199]
LGR5 TTTSGRH Limited Biomarker [200]
LIPA TTS8T1M Limited Biomarker [201]
LRP5 TT7VMG4 Limited Genetic Variation [202]
MBL2 TTMQDZ5 Limited Genetic Variation [203]
MCHR2 TTS17MG Limited Biomarker [204]
MOGAT2 TTN17BP Limited Biomarker [205]
NOD2 TTYPUHA Limited Biomarker [206]
NR0B1 TTTK36V Limited Genetic Variation [207]
NR0B2 TT25A9Q Limited Altered Expression [208]
NR4A3 TTJQB49 Limited Biomarker [209]
NTRK2 TTKN7QR Limited Biomarker [210]
OLR1 TTKSND3 Limited Biomarker [211]
OTC TT5KIO9 Limited Biomarker [212]
PDE3A TT06AWU Limited Biomarker [213]
PDE3B TTN34SQ Limited Biomarker [214]
PLA2G1B TT9V5JH Limited Biomarker [215]
PRDX4 TTPBL9I Limited Altered Expression [216]
PRKAR1A TTNAHEX Limited Biomarker [217]
PRKCD TT7A1BO Limited Biomarker [218]
PTPRB TT64I9Q Limited Altered Expression [219]
RHOA TTP2U16 Limited Biomarker [220]
RNASEL TT7V0K4 Limited Altered Expression [221]
RXFP3 TT64ZVP Limited Genetic Variation [222]
S100A9 TT0TMQG Limited Altered Expression [223]
SCN10A TT90XZ8 Limited Altered Expression [224]
SFRP4 TTX8I1Y Limited Biomarker [225]
SLC2A12 TTZO36H Limited Biomarker [226]
SLC38A2 TTUSC27 Limited Altered Expression [227]
SLC6A14 TTB6H2S Limited Genetic Variation [228]
SLC9A3 TTFZVPO Limited Biomarker [229]
SOD2 TT9O4C5 Limited Biomarker [230]
SOST TTYRO4F Limited Biomarker [231]
SRD5A1 TTTU72V Limited Biomarker [232]
TH TTUHP71 Limited Altered Expression [233]
TLR5 TTCXP8J Limited Biomarker [234]
TSLP TTHMW3T Limited Biomarker [235]
TST TT51OTS Limited Genetic Variation [236]
VWF TT3SZBT Limited Altered Expression [237]
ABCG5 TTKZ7WY Disputed ModifyingMutation [238]
CDKN1B TTLGFVW Disputed Biomarker [239]
EHMT1 TTOFXD7 Disputed Biomarker [240]
GIPR TTYMKBE Disputed Biomarker [241]
MAPT TTS87KH Disputed Biomarker [242]
SLC10A1 TTWZRY5 Disputed ModifyingMutation [238]
ADORA2A TTM2AOE moderate Biomarker [243]
AKT2 TTH24WI moderate Genetic Variation [244]
ALPL TTMR5UV moderate Biomarker [245]
AR TTKPW01 moderate Genetic Variation [246]
ARRB2 TT8SO2I moderate Biomarker [247]
ATP2A2 TTE6THL moderate Genetic Variation [248]
BCAT1 TTES57P moderate Biomarker [249]
BCAT2 TTF9OQ6 moderate Biomarker [249]
C3 TTJGY7A moderate Altered Expression [250]
CAV1 TTXUBN2 moderate Altered Expression [251]
CCL17 TTMPHAE moderate Genetic Variation [252]
CCL5 TT9DWLC moderate Biomarker [253]
CD248 TTYJWT7 moderate Altered Expression [254]
CDK8 TTBJR4L moderate Biomarker [255]
CDKN2A TTFTWQ8 moderate Biomarker [256]
CLCN3 TT8XNZ7 moderate Biomarker [257]
COMT TTKWFB8 moderate Genetic Variation [258]
CPN1 TT8V2KD moderate Biomarker [259]
CRY2 TTAO58M moderate Biomarker [260]
CXCL2 TTZF0K2 moderate Altered Expression [261]
DAPK3 TTERVQN moderate Altered Expression [262]
DDIT4 TTVEOY6 moderate Altered Expression [263]
F2RL2 TTVSEBF moderate Biomarker [264]
FPR2 TTOJ1NF moderate Biomarker [265]
GDF5 TT37XV9 moderate Biomarker [266]
HCAR1 TTVK4ZO moderate Biomarker [267]
HNF1A TT01M3K moderate Genetic Variation [268]
HP TTLC8E1 moderate Biomarker [269]
IFNL1 TTM624L moderate Biomarker [270]
ITGB6 TTKQSXZ moderate Biomarker [271]
KDM4C TTV8CRH moderate Altered Expression [272]
KHK TTPAFR9 moderate Genetic Variation [157]
LALBA TTBRLU3 moderate Biomarker [273]
MAPK7 TTU6FSC moderate Altered Expression [274]
MELK TTBZOTY moderate Biomarker [275]
PIKFYVE TTA4M1N moderate Biomarker [276]
PNLIP TTXMY0J moderate Biomarker [277]
PRKCB TTYPXQF moderate Biomarker [278]
PTGDR TTNVEIR moderate Biomarker [279]
PTGES TTYLQ8V moderate Biomarker [280]
RASA1 TTPNZ1F moderate Biomarker [281]
RPS6KB1 TTG0U4H moderate Biomarker [282]
RSPO1 TTI9HL4 moderate Altered Expression [283]
SLC22A6 TTTYH7A moderate Altered Expression [196]
SLC2A9 TTIF3GB moderate Genetic Variation [284]
SPHK2 TTCN0M9 moderate Biomarker [285]
TAGLN2 TTP6BIJ moderate Biomarker [286]
TMEM97 TT9NXW4 moderate Biomarker [287]
TNFRSF17 TTZ3P4W moderate Biomarker [288]
TNFRSF25 TTDV6BQ moderate Genetic Variation [289]
TPH2 TT3KLDP moderate Genetic Variation [290]
TXNRD3 TTDYFVB moderate Biomarker [291]
TYRO3 TTIEMFN moderate Biomarker [292]
ABCA4 TTLB52K Strong Biomarker [293]
ABCC8 TTP835K Strong Altered Expression [294]
ABCG1 TTMWDGU Strong Altered Expression [295]
ABHD6 TTSINOV Strong Biomarker [296]
ACE2 TTUI5H7 Strong Altered Expression [297]
ACHE TT1RS9F Strong Biomarker [298]
ACKR3 TTRQJTC Strong Biomarker [299]
ACLY TT0Z6Y2 Strong Biomarker [154]
ADAMTS1 TTS2TEI Strong Biomarker [300]
ADAMTS5 TTXSU2Y Strong Biomarker [301]
ADCY5 TTN64VU Strong Altered Expression [302]
ADCYAP1 TTW4LYC Strong Genetic Variation [303]
ADM TTV14YH Strong Altered Expression [304]
ADM2 TTM642F Strong Biomarker [305]
ADORA1 TTK25J1 Strong Biomarker [306]
ADORA2B TTNE7KG Strong Altered Expression [307]
ADORA3 TTJFY5U Strong Biomarker [307]
ADRA1A TTNGILX Strong Biomarker [299]
ADRA2A TTWG9A4 Strong Genetic Variation [308]
ADRA2B TTWM4TY Strong Biomarker [299]
AGER TTMO9HF Strong Biomarker [309]
AGPAT2 TT9AYVR Strong Biomarker [310]
AIF1 TT12MEP Strong Biomarker [311]
AIMP2 TTXWHGF Strong Altered Expression [266]
AKR1C3 TT5ZWB6 Strong Biomarker [154]
AKT1 TTWTSCV Strong Biomarker [312]
AKT3 TTO6SGY Strong Biomarker [313]
ALOX12 TT12ABZ Strong Biomarker [314]
AMACR TTLN1AP Strong Altered Expression [315]
AMD1 TTBFROQ Strong Genetic Variation [316]
AMY2A TTCGSZ4 Strong Genetic Variation [317]
ANGPT1 TTWNQ1T Strong Biomarker [318]
ANGPTL3 TT59GO7 Strong Altered Expression [319]
ANGPTL4 TTWALY5 Strong Altered Expression [320]
ANPEP TTPHMWB Strong Biomarker [321]
ANTXR2 TTOD34I Strong Biomarker [322]
AOC3 TT7HC21 Strong Biomarker [323]
APLNR TTJ8E43 Strong Genetic Variation [324]
APOA1 TT5S8DR Strong Genetic Variation [325]
APOA2 TTGQA9W Strong Biomarker [326]
APOB TTN1IE2 Strong Biomarker [327]
APOC3 TTXOZQ1 Strong Genetic Variation [328]
APP TTE4KHA Strong Biomarker [329]
AQP7 TTNGCRK Strong Biomarker [330]
AQP9 TTQEI32 Strong Altered Expression [331]
ARG1 TT7ZQEV Strong Altered Expression [332]
ARG2 TTV1AG6 Strong Biomarker [333]
ARSA TTYQANR Strong Biomarker [334]
ASPA TT6TLZP Strong Altered Expression [335]
ASRGL1 TT4WT91 Strong Genetic Variation [336]
ATF3 TTCE793 Strong Biomarker [337]
ATIC TT9NVXQ Strong Biomarker [338]
ATP7B TTOPO51 Strong Altered Expression [339]
AURKB TT9RTBL Strong Genetic Variation [340]
AVP TTJ8EWH Strong Altered Expression [341]
AVPR1A TT4TFGN Strong Biomarker [342]
AVPR1B TTL9MHW Strong Genetic Variation [343]
AZGP1 TTUPYLV Strong Biomarker [344]
BCHE TT3MSAO Strong Genetic Variation [345]
BCL2A1 TTGT9C7 Strong Biomarker [346]
BDKRB2 TTGY8IW Strong Genetic Variation [347]
BGN TT0JPVF Strong Altered Expression [348]
BIRC2 TTQ5LRD Strong Altered Expression [349]
BLK TTNDSC3 Strong Genetic Variation [350]
BMP2K TT32VXH Strong Biomarker [351]
BMP4 TTD3BSX Strong Biomarker [352]
BMPR2 TTGKF90 Strong Biomarker [353]
BRD2 TTDP48B Strong Biomarker [180]
BRD7 TT07ZS1 Strong Altered Expression [354]
BRS3 TTKYEPM Strong Biomarker [299]
C1QBP TTWTD7F Strong Biomarker [355]
C3AR1 TTI6B3F Strong Biomarker [356]
CA3 TTXUK5D Strong Biomarker [357]
CA5A TT75WPO Strong Biomarker [358]
CAD TT2YT1K Strong Biomarker [359]
CALCRL TTY6O0Q Strong Altered Expression [360]
CAMKK2 TTV298Y Strong Biomarker [361]
CAPN1 TT1WBIJ Strong Biomarker [362]
CAPN2 TTG5QB7 Strong Genetic Variation [362]
CASP1 TTCQIBE Strong Biomarker [363]
CBR1 TTVG0SN Strong Biomarker [364]
CBS TTVZJ7G Strong Biomarker [365]
CCKBR TTVFO0U Strong Biomarker [366]
CCL11 TTCF05Y Strong Biomarker [367]
CCL2 TTNAY0P Strong Biomarker [368]
CCL20 TT2XAZY Strong Genetic Variation [252]
CCL22 TTBTWI1 Strong Genetic Variation [369]
CCNE1 TTCEJ4F Strong Biomarker [370]
CCR9 TTIPS8B Strong Genetic Variation [371]
CD14 TT6I7DC Strong Altered Expression [372]
CD24 TTCTYNP Strong Altered Expression [373]
CD33 TTJVYO3 Strong Genetic Variation [374]
CD38 TTPURFN Strong Altered Expression [375]
CD40 TT1ERKL Strong Biomarker [376]
CD59 TTBGTEJ Strong Genetic Variation [377]
CD74 TTCMYP9 Strong Biomarker [378]
CDH11 TTRGWZC Strong Biomarker [379]
CDH2 TT1WS0T Strong Genetic Variation [380]
CEACAM1 TTA9CK4 Strong Posttranslational Modification [381]
CEACAM5 TTY6DTE Strong Biomarker [382]
CEBPA TT5LWG1 Strong Biomarker [383]
CEBPB TTUI35N Strong Genetic Variation [384]
CEL TTTRNQW Strong Biomarker [385]
CERK TT9XRNV Strong Biomarker [386]
CFB TTA0P7K Strong Biomarker [387]
CFD TT8D13I Strong Biomarker [388]
CHRM2 TTYEG6Q Strong Genetic Variation [389]
CHRNA2 TTF4E0J Strong Altered Expression [390]
CHRNA5 TTH2QRX Strong Genetic Variation [391]
CHRNB4 TTTVAFQ Strong Genetic Variation [392]
CLCN7 TTST1AJ Strong Biomarker [393]
CLK2 TT85TPS Strong Biomarker [394]
CLN3 TTORF9W Strong Biomarker [395]
CMA1 TT8VUE0 Strong Biomarker [396]
CMKLR1 TT4UGZL Strong Biomarker [397]
CNTF TTGEM5Q Strong Biomarker [398]
COL6A3 TT5WCAH Strong Biomarker [399]
CPB2 TTP18AY Strong Biomarker [400]
CPT1B TTDL0NY Strong Altered Expression [401]
CRHBP TT3PKZE Strong Biomarker [402]
CRHR2 TTIY658 Strong Biomarker [403]
CRK TTFEUYR Strong Altered Expression [266]
CRTC1 TT4GO0F Strong Biomarker [404]
CRTC2 TTFWETR Strong Altered Expression [405]
CRY1 TT5MLZR Strong Biomarker [260]
CSK TTX6F0Q Strong Genetic Variation [406]
CTF1 TTXGTZU Strong Biomarker [407]
CTSK TTDZN01 Strong Biomarker [408]
CTSS TTUMQVO Strong Biomarker [409]
CXCL11 TTWG0RE Strong Biomarker [410]
CXCR6 TT2BVUA Strong Biomarker [299]
CYP1A2 TTS1DTU Strong Altered Expression [411]
CYP1B1 TTI84H7 Strong Genetic Variation [412]
CYP21A2 TTP4GLG Strong Genetic Variation [413]
CYP24A1 TT82UI1 Strong Genetic Variation [414]
CYP2A6 TTAQ6ZW Strong Biomarker [415]
CYP2B6 TTMH124 Strong Biomarker [416]
CYP2C9 TTR40YJ Strong Genetic Variation [417]
CYP2E1 TTWVHQ5 Strong Biomarker [418]
DAG1 TT4X7PG Strong Biomarker [419]
DCN TTB3XAN Strong Altered Expression [420]
DGAT1 TT0GV3R Strong Biomarker [421]
DIO1 TTU3X26 Strong Altered Expression [422]
DLK1 TTF4AVB Strong Biomarker [423]
DPP4 TTDIGC1 Strong Biomarker [424]
DPYD TTZPS91 Strong Biomarker [154]
DRD1 TTZFYLI Strong Genetic Variation [425]
DRD5 TTS2PH3 Strong Genetic Variation [426]
DUSP1 TTG8HIM Strong Altered Expression [427]
DUSP5 TTZN92A Strong Altered Expression [428]
DUSP9 TT1GV6C Strong Biomarker [429]
EDNRA TTKRD0G Strong Biomarker [299]
EGF TTED8JB Strong Biomarker [430]
EGFL6 TTXJGAR Strong Altered Expression [431]
EGLN1 TT9ISBX Strong Biomarker [432]
EIF2AK2 TTXEZJ4 Strong Biomarker [433]
EIF2AK4 TT9U4EP Strong Biomarker [434]
EIF4EBP2 TTNBTCW Strong Biomarker [435]
ELANE TTPLTSQ Strong Biomarker [436]
ENPEP TT9PBIL Strong Biomarker [437]
ENPP2 TTSCIM2 Strong Altered Expression [438]
EP300 TTGH73N Strong Biomarker [439]
ERN1 TTKIAT3 Strong Altered Expression [440]
ESR2 TTOM3J0 Strong Biomarker [441]
ESRRA TTPNQAC Strong Biomarker [442]
ESRRB TTKF0XS Strong Biomarker [443]
F10 TTCIHJA Strong Biomarker [444]
F11 TTDM4ZU Strong Biomarker [445]
F11R TT3C8EG Strong Genetic Variation [446]
F13A1 TTXI2RA Strong Biomarker [447]
F2 TT6L509 Strong Genetic Variation [448]
F2RL1 TTQR74A Strong Biomarker [449]
FABP3 TT3TGLR Strong Biomarker [450]
FABP4 TTHWMFZ Strong Biomarker [451]
FADS2 TTT2VDU Strong Genetic Variation [452]
FASN TT7AOUD Strong Biomarker [453]
FAT1 TTGUJYV Strong Biomarker [454]
FBXO3 TTUX14L Strong Biomarker [455]
FCGR1A TTZK4I3 Strong Biomarker [456]
FCGR2B TT5RWKQ Strong Biomarker [457]
FDPS TTIKWV4 Strong Biomarker [458]
FDXR TT3W4IX Strong Genetic Variation [459]
FES TTLBY21 Strong Biomarker [458]
FFAR1 TTB8FUC Strong Biomarker [460]
FFAR3 TTXDOHN Strong Posttranslational Modification [461]
FFAR4 TT08JVB Strong Biomarker [462]
FGF10 TTNPEFX Strong Biomarker [463]
FGF18 TT6ICRA Strong Genetic Variation [464]
FGF19 TTGCH11 Strong Altered Expression [465]
FGFR1 TTRLW2X Strong Altered Expression [466]
FGFR3 TTST7KB Strong Biomarker [467]
FOXO1 TTLRVIA Strong Biomarker [468]
FST TTDNM9W Strong Biomarker [469]
FYN TT2B9KF Strong Posttranslational Modification [470]
GAL TTXZAJ5 Strong Biomarker [471]
GALE TTGRHIB Strong Genetic Variation [472]
GAPDH TTUGSWA Strong Altered Expression [473]
GATA4 TT1VDN2 Strong Genetic Variation [474]
GCGR TT9O6WS Strong Biomarker [475]
GDF2 TTAP4T1 Strong Altered Expression [476]
GEM TTAZF9M Strong Biomarker [477]
GH1 TTT3YKH Strong Biomarker [478]
GHR TTHJWYD Strong Biomarker [479]
GIP TT40HS5 Strong Biomarker [480]
GJA3 TTFZRG0 Strong Genetic Variation [481]
GJA4 TTQO1VY Strong Biomarker [482]
GJA8 TTJ7ATH Strong Genetic Variation [481]
GJC1 TTEP7OC Strong Altered Expression [482]
GLO1 TTV9A7R Strong Genetic Variation [483]
GLRX TTRJCNG Strong Biomarker [484]
GLUL TTURQ2G Strong Biomarker [154]
GNAQ TTL1SRG Strong Biomarker [485]
GNRH1 TT0ID4A Strong Altered Expression [486]
GNRHR TT8R70G Strong Altered Expression [487]
GPBAR1 TTSDVTR Strong Biomarker [488]
GPD1 TTKTEAH Strong Genetic Variation [489]
GPER1 TTDSB34 Strong Biomarker [490]
GPR119 TT7QNVC Strong Biomarker [491]
GPR35 TT254XD Strong Altered Expression [492]
GPR39 TTTPCNU Strong Biomarker [493]
GPR55 TTNET8J Strong Altered Expression [494]
GPR84 TTG0MQD Strong Altered Expression [495]
GPRC6A TTI1PRE Strong Biomarker [356]
GPX1 TTYAHBP Strong Biomarker [496]
GRIN1 TTLD29N Strong Biomarker [497]
GRK2 TTAZ3MN Strong Altered Expression [498]
GRK5 TTTCXO0 Strong Biomarker [499]
GSR TTEP6RV Strong Altered Expression [500]
GSTO1 TTWO3SH Strong Biomarker [501]
GUCY2C TTLDPRG Strong Biomarker [502]
GUCY2D TTWNFC2 Strong Genetic Variation [503]
HCAR3 TT8WFXV Strong Biomarker [504]
HDAC4 TTTQGH8 Strong Altered Expression [166]
HEXA TTJI5JW Strong Genetic Variation [505]
HK2 TTK02H8 Strong Biomarker [154]
HLA-DRB1 TTUXSTW Strong Genetic Variation [506]
HMBS TTT0HW3 Strong Biomarker [507]
HMGB2 TTA78JQ Strong Biomarker [154]
HMOX1 TTI6V2A Strong Altered Expression [508]
HNRNPA1 TTPJ9XK Strong Biomarker [509]
HRH3 TT9JNIC Strong Biomarker [510]
HSD11B2 TT9H85R Strong Genetic Variation [511]
HSD17B1 TTIWB6L Strong Genetic Variation [512]
HSF1 TTN6STZ Strong Biomarker [513]
HSPA5 TTW26OG Strong Altered Expression [514]
HSPD1 TT9HL5R Strong Biomarker [515]
HTR1D TT6MSOK Strong Genetic Variation [516]
HTR2A TTJQOD7 Strong Biomarker [517]
HTR3A TTPC4TU Strong Altered Expression [518]
HTR6 TTJS8PY Strong Biomarker [519]
ICAM1 TTA1L39 Strong Altered Expression [520]
ID1 TTBXVDE Strong Biomarker [521]
IDE TT2EDHU Strong Biomarker [522]
IDO1 TTZJYKH Strong Altered Expression [523]
IFNL3 TTRF4Q2 Strong Genetic Variation [524]
IGF1R TTQFBMY Strong Genetic Variation [525]
IGFBP1 TTCJTWF Strong Genetic Variation [526]
IKBKB TTJ3E9X Strong Biomarker [433]
IL15 TTJFA35 Strong Biomarker [527]
IL16 TTW4R0B Strong Biomarker [528]
IL17A TTG0MT6 Strong Altered Expression [529]
IL18 TTRICUF Strong Altered Expression [530]
IL1A TTPM6HI Strong Altered Expression [530]
IL1RAP TTWS50K Strong Genetic Variation [531]
IL1RN TT6GSR3 Strong Altered Expression [532]
IL22 TTLDX4N Strong Biomarker [533]
IL25 TTVMO5W Strong Altered Expression [534]
IL2RB TT9721Y Strong Genetic Variation [464]
IL32 TTD4G7L Strong Altered Expression [535]
IL33 TT5MD4P Strong Biomarker [536]
IL37 TTQTX98 Strong Biomarker [537]
IRAK3 TTBPJOK Strong Biomarker [538]
IRF3 TTYR7OH Strong Altered Expression [539]
IRS2 TTF95B8 Strong Biomarker [540]
ITCH TT5SEWD Strong Biomarker [541]
ITGAM TTB69FJ Strong Biomarker [376]
ITPR2 TTK9OV3 Strong Biomarker [542]
ITPR3 TTH1769 Strong Genetic Variation [543]
JAK2 TTRMX3V Strong Altered Expression [544]
JAK3 TTT7PJU Strong Altered Expression [545]
KAT2B TTVK7SB Strong Biomarker [546]
KCNJ5 TTEO25X Strong Genetic Variation [547]
KCNK9 TTL4FMB Strong Biomarker [548]
KCNQ1 TT846HF Strong Biomarker [549]
KDM3A TTKXS4A Strong Biomarker [550]
KDM6B TTDIJUQ Strong Posttranslational Modification [551]
KHDRBS1 TTAT6C7 Strong Biomarker [552]
KIR2DL1 TT4UXPE Strong Altered Expression [553]
KIR2DS1 TTVWAGF Strong Biomarker [554]
KIR3DL2 TTQH3N0 Strong Biomarker [554]
KISS1 TTU2O6T Strong Biomarker [555]
KISS1R TT3KBZY Strong Biomarker [556]
KLB TTARBVH Strong Genetic Variation [557]
KLK7 TTE6GTB Strong Biomarker [558]
KNG1 TTDJ4MY Strong Biomarker [559]
LBP TTVQJLY Strong Altered Expression [560]
LCAT TTGZ91P Strong Biomarker [561]
LCT TTA0OSE Strong Genetic Variation [562]
LDLR TTH0DUS Strong Biomarker [563]
LGR4 TTY6C71 Strong Genetic Variation [564]
LIPE TTLUQ8E Strong Altered Expression [565]
LNPEP TTY2KP7 Strong Biomarker [566]
LONP1 TTM1VPZ Strong Altered Expression [567]
LPA TTU9LGY Strong Biomarker [568]
LPAR2 TTB7Y8I Strong Biomarker [299]
LPAR3 TTE2YJR Strong Biomarker [356]
LPAR4 TT7ZMY4 Strong Biomarker [569]
LPAR5 TTABCJ6 Strong Altered Expression [570]
LY75 TTG180Q Strong Biomarker [571]
LY96 TT8S9AV Strong Biomarker [572]
MAOA TT3WG5C Strong Genetic Variation [573]
MAOB TTGP7BY Strong Genetic Variation [574]
MAP2K5 TTV3O87 Strong Genetic Variation [575]
MAP3K3 TTJZNIG Strong Biomarker [576]
MAP3K7 TTJQT60 Strong Biomarker [577]
MAP3K8 TTGECUM Strong Altered Expression [578]
MAP4K4 TT6NI13 Strong Biomarker [579]
MAPK10 TT056SO Strong Altered Expression [580]
MAPK9 TT3IVG2 Strong Biomarker [581]
MAPKAPK5 TT3UJ7Z Strong Altered Expression [582]
MARK3 TT3DCYJ Strong Genetic Variation [583]
MAS1 TTOISYB Strong Altered Expression [584]
MBOAT4 TTSYOWR Strong Biomarker [585]
MBP TT2RY5P Strong Altered Expression [586]
MC1R TT0MV2T Strong Genetic Variation [587]
MC2R TTPWFDX Strong Altered Expression [588]
MC5R TT6QAJ3 Strong Biomarker [589]
MCHR1 TTX4RTB Strong Biomarker [590]
MCL1 TTL53M6 Strong Biomarker [591]
METAP2 TTZL0OI Strong Biomarker [592]
MGAM TTXWASR Strong Altered Expression [593]
MGAT1 TTYJRN5 Strong Altered Expression [594]
MGAT2 TTJOW1I Strong Biomarker [205]
MGLL TTZ963I Strong Biomarker [595]
MKRN1 TTITER7 Strong Biomarker [596]
MLYCD TT9Z4YD Strong Altered Expression [597]
MME TT5TKPM Strong Biomarker [598]
MMP15 TTNSTO3 Strong Biomarker [599]
MPO TTVCZPI Strong Biomarker [600]
MRC1 TTKV8W5 Strong Biomarker [376]
MRGPRX1 TTIX6PK Strong Biomarker [356]
MST1R TTBQ3OC Strong Biomarker [601]
MTOR TTCJG29 Strong Altered Expression [593]
MTTP TTUS1RD Strong Biomarker [602]
MUSK TT6SA0X Strong Genetic Variation [603]
MYD88 TTB6Q2O Strong Biomarker [604]
MYH7 TTNIMDP Strong Biomarker [605]
NAAA TTMN4HY Strong Biomarker [606]
NAMPT TTD1WIG Strong Altered Expression [607]
NCF1 TTZ4JC3 Strong Altered Expression [608]
NCK1 TTMA3VF Strong Biomarker [609]
NF2 TTZIK7P Strong Genetic Variation [610]
NISCH TT789FN Strong Altered Expression [611]
NLRP3 TT4EN8X Strong Biomarker [612]
NMUR2 TT2L6C5 Strong Altered Expression [613]
NNT TTKIH76 Strong Biomarker [614]
NOS1 TTZUFI5 Strong Biomarker [615]
NOX4 TTQRBSJ Strong Biomarker [616]
NPC1L1 TTPD1CN Strong Biomarker [617]
NPEPPS TT371QC Strong Biomarker [618]
NPFFR2 TTXYNDJ Strong Genetic Variation [619]
NPPB TTY63XT Strong Altered Expression [620]
NPPC TTRK0B9 Strong Altered Expression [621]
NPR1 TTM9IYA Strong Biomarker [622]
NPY1R TTRK9JT Strong Biomarker [623]
NPY4R TTW4N16 Strong Genetic Variation [624]
NQO1 TT8XK6L Strong Biomarker [625]
NR1D1 TTAD1O8 Strong Biomarker [626]
NR1H2 TTXA6PH Strong ModifyingMutation [238]
NR1I2 TT7LCTF Strong Biomarker [627]
NR1I3 TTRANFM Strong Biomarker [217]
NR3C2 TT26PHO Strong Genetic Variation [628]
NR4A1 TTMXE2Q Strong Biomarker [629]
NR4A2 TT9HKN3 Strong Biomarker [630]
NRG4 TTWAGKJ Strong Biomarker [631]
NTSR1 TTTUMEP Strong Biomarker [632]
OGG1 TTRU01G Strong Genetic Variation [633]
OLFM4 TTK1CX7 Strong Genetic Variation [634]
OPRD1 TT27RFC Strong Genetic Variation [635]
OPRM1 TTKWM86 Strong Genetic Variation [636]
OSM TTIVXSE Strong Biomarker [637]
OXER1 TT7WBSV Strong Biomarker [356]
OXTR TTSCIUP Strong Altered Expression [638]
P2RY12 TTZ1DT0 Strong Genetic Variation [639]
P2RY2 TTOZHQC Strong Biomarker [640]
PADI4 TTQHAXM Strong Biomarker [641]
PAM TTF4ZPC Strong Biomarker [642]
PARP1 TTVDSZ0 Strong Biomarker [643]
PARP2 TTQ4V96 Strong Biomarker [644]
PASK TTC0V1J Strong Biomarker [645]
PAX5 TTA4REJ Strong Genetic Variation [646]
PCSK7 TTD30LY Strong Biomarker [647]
PDE11A TTTWC79 Strong Genetic Variation [648]
PDE4B TTVIAT9 Strong Biomarker [649]
PDK1 TTCZOF2 Strong Altered Expression [650]
PDK2 TTJGCKM Strong Altered Expression [651]
PDX1 TT8SGZK Strong Altered Expression [652]
PDXK TTXI3KF Strong Altered Expression [653]
PEMT TT735V2 Strong Genetic Variation [654]
PFKFB3 TTTHMQJ Strong Biomarker [154]
PGC TT7K6AD Strong Biomarker [655]
PGR TTUV8G9 Strong Biomarker [656]
PHB TT6U071 Strong Genetic Variation [657]
PIK3CB TT9H4P3 Strong Biomarker [658]
PIN1 TTJNTSI Strong Biomarker [659]
PKM TT4LOT8 Strong Biomarker [660]
PLA2G4A TTT1JVS Strong Altered Expression [661]
PLA2G7 TTDNFMT Strong Biomarker [662]
PLD1 TT3T17P Strong Genetic Variation [663]
PLG TTP86E2 Strong Biomarker [664]
PLIN1 TTIV27N Strong Biomarker [665]
PLOD2 TT8MEUD Strong Genetic Variation [666]
PLTP TTZF6SN Strong Biomarker [667]
PPARD TT2JWF6 Strong Biomarker [668]
PPARGC1B TTKSQ3W Strong Biomarker [230]
PPIB TT6ZFQ4 Strong Altered Expression [669]
PPID TTNAFOU Strong Altered Expression [670]
PPIF TTRFQTB Strong Altered Expression [670]
PRCP TTTJZ4M Strong Biomarker [671]
PRDX5 TTLPJWH Strong Genetic Variation [672]
PREP TTNGKET Strong Genetic Variation [673]
PRG4 TTSKF4V Strong Biomarker [674]
PRKAR2B TTW4Y2M Strong Biomarker [675]
PRKCH TTONI0R Strong Genetic Variation [676]
PRKCZ TTBSN0L Strong Biomarker [677]
PRKD1 TTSLUMT Strong Biomarker [678]
PRKDC TTK3PY9 Strong Biomarker [679]
PRKG1 TT7IZSA Strong Altered Expression [680]
PRL TTJ2TSA Strong Genetic Variation [681]
PROC TTZUXYS Strong Biomarker [682]
PSMB6 TT8EPLT Strong Genetic Variation [384]
PTGES2 TTWU04I Strong Genetic Variation [683]
PTGS2 TTVKILB Strong Biomarker [684]
PTH TT6F7GZ Strong Biomarker [685]
PTPN2 TTY8PUS Strong Biomarker [686]
PTPRJ TTWMKXP Strong Biomarker [687]
PTPRS TTCWXFA Strong Biomarker [688]
RAPGEF4 TTOS63B Strong Biomarker [689]
REG3A TTL4H8N Strong Biomarker [690]
RENBP TTZCG0Q Strong Genetic Variation [691]
RGMA TTURJV4 Strong Genetic Variation [692]
RGS2 TTKB7T3 Strong Altered Expression [693]
RGS4 TTGTKX9 Strong Biomarker [694]
RGS6 TTJ96M8 Strong Biomarker [281]
ROBO1 TTND1YP Strong Genetic Variation [695]
ROBO4 TT3S9TY Strong Genetic Variation [696]
RORC TTGV6LY Strong Biomarker [697]
ROS1 TTSZ6Y3 Strong Altered Expression [608]
S100A12 TTQ4ESF Strong Altered Expression [698]
S100A6 TT716MY Strong Genetic Variation [699]
S100A8 TT4AF6N Strong Biomarker [700]
S1PR2 TTVSMOH Strong Biomarker [701]
SAA1 TTY0DN9 Strong Biomarker [702]
SCARB1 TTRE324 Strong Biomarker [703]
SCD TT6RIOV Strong Biomarker [704]
SCG3 TTY5R9H Strong Genetic Variation [705]
SDC1 TTYDSVG Strong Biomarker [706]
SDC2 TT5H2F0 Strong Biomarker [706]
SELP TTE5VG0 Strong Altered Expression [707]
SELPLG TTS5K8U Strong Biomarker [708]
SEMA4D TT5UT28 Strong Altered Expression [709]
SERPINA6 TTJL8VG Strong Genetic Variation [710]
SETD2 TTPC3H4 Strong Altered Expression [711]
SFTPD TTGLMU7 Strong Biomarker [712]
SGK1 TTTV8EJ Strong Biomarker [713]
SH3GL1 TTTYNAM Strong Biomarker [714]
SIK2 TTCUGZR Strong Biomarker [715]
SIK3 TTW6L4V Strong Genetic Variation [716]
SIRT1 TTUF2HO Strong Biomarker [717]
SIRT2 TTLKF5M Strong Biomarker [717]
SIRT3 TTVZLIJ Strong Biomarker [718]
SIRT5 TTH0IOD Strong Biomarker [719]
SLC12A3 TTP362L Strong Genetic Variation [720]
SLC15A1 TT5LF3C Strong Biomarker [721]
SLC19A1 TT09I7D Strong Posttranslational Modification [722]
SLC22A1 TTM5Q4V Strong Biomarker [723]
SLC22A12 TTA592U Strong Genetic Variation [724]
SLC22A2 TT0XOJN Strong Biomarker [725]
SLC22A3 TTG2UMS Strong Biomarker [725]
SLC22A8 TTTQR47 Strong Altered Expression [196]
SLC27A4 TT20AYF Strong Biomarker [726]
SLC30A8 TTXIGT7 Strong Biomarker [727]
SLC33A1 TTL69WB Strong Biomarker [728]
SLC37A4 TT1KPBZ Strong Altered Expression [729]
SLC38A1 TT1YE9Z Strong Biomarker [730]
SLC38A5 TTC8YPT Strong Altered Expression [731]
SLC5A1 TT2UE56 Strong Biomarker [732]
SLC5A2 TTF8JAT Strong Biomarker [733]
SLC6A12 TTQBMPI Strong Biomarker [734]
SLC6A2 TTAWNKZ Strong Biomarker [696]
SLC8A1 TTCF82X Strong Genetic Variation [676]
SLIT2 TTDWK85 Strong Genetic Variation [735]
SMAD6 TTON5JB Strong Altered Expression [736]
SNAP25 TTYQWA0 Strong Genetic Variation [737]
SNCG TT5TQNZ Strong Altered Expression [738]
SOCS1 TT8COJM Strong Biomarker [739]
SOD1 TTP9K3Q Strong Biomarker [740]
SORT1 TTRX9AV Strong Biomarker [741]
SOX2 TTCNOT6 Strong Biomarker [742]
SPARC TTBQFM7 Strong Biomarker [743]
SPDEF TT2ZUPY Strong Biomarker [744]
SPHK1 TTOHFIY Strong Biomarker [745]
SPRY1 TT0PSN6 Strong Biomarker [746]
SPTBN1 TTS9BDA Strong Biomarker [747]
SQSTM1 TTOT2RY Strong Biomarker [552]
SREBF1 TTER0UB Strong Altered Expression [748]
SREBF2 TTRQ4AP Strong Genetic Variation [749]
SSTR2 TTZ6T9E Strong Genetic Variation [750]
SSTR4 TTAE1BR Strong Biomarker [299]
STC1 TTDLUER Strong Biomarker [751]
STK33 TTP34DQ Strong Genetic Variation [752]
STK39 TTYQTIU Strong Biomarker [753]
STS TTHM0R1 Strong Altered Expression [754]
SUCNR1 TT4FX9Y Strong Biomarker [755]
SULF2 TTLQTHB Strong Genetic Variation [756]
SUV39H1 TTUWQTK Strong Biomarker [757]
SYVN1 TT8XKYM Strong Biomarker [758]
TAAR1 TTIU98M Strong Biomarker [759]
TAOK3 TTO7L0V Strong Posttranslational Modification [470]
TBK1 TTMP03S Strong Biomarker [760]
TBL1X TTAL6S1 Strong Altered Expression [761]
TBL1XR1 TTYXT16 Strong Altered Expression [761]
TBXA2R TT2O84V Strong Genetic Variation [762]
TEK TT9VGXW Strong Altered Expression [763]
TF TT8WXAV Strong Biomarker [154]
TFRC TT8MG4S Strong Biomarker [764]
TGFB3 TTWOMY8 Strong Altered Expression [765]
THBD TTAPV67 Strong Biomarker [766]
THBS1 TTKI0H1 Strong Biomarker [767]
THRA TTTSEPU Strong Genetic Variation [768]
THRB TTGER3L Strong Genetic Variation [769]
TICAM1 TT2GQT6 Strong Altered Expression [770]
TIE1 TTT4236 Strong Biomarker [771]
TKTL1 TTNQ1J3 Strong Biomarker [772]
TLR3 TTD24Y0 Strong Biomarker [773]
TLR8 TT8CWFK Strong Biomarker [774]
TMPRSS15 TTXL0GC Strong Biomarker [775]
TMPRSS2 TT1GM2Z Strong Biomarker [776]
TMPRSS6 TTL9KE7 Strong Biomarker [777]
TNFRSF12A TTKPS7V Strong Biomarker [778]
TNFRSF1A TTG043C Strong Biomarker [779]
TNFRSF4 TTL31H0 Strong Altered Expression [780]
TNFSF12 TTBTDM1 Strong Altered Expression [781]
TNFSF14 TTKVENM Strong Altered Expression [782]
TNKS TTVUSO7 Strong Genetic Variation [783]
TNNI3 TTNLDK6 Strong Biomarker [784]
TREM1 TTHZQP0 Strong Altered Expression [785]
TREM2 TTQRMSJ Strong Altered Expression [785]
TRH TT2Z39D Strong Biomarker [786]
TRIM24 TT9Q7AE Strong Biomarker [787]
TRIM28 TTQ2BKV Strong Biomarker [788]
TRPC1 TTA76X0 Strong Biomarker [789]
TRPC3 TTNVC34 Strong Genetic Variation [790]
TRPM2 TTEBMN7 Strong Biomarker [791]
TRPM5 TT1N8F3 Strong Biomarker [792]
TRPM8 TTXDKTO Strong Biomarker [793]
TRPV1 TTMI6F5 Strong Biomarker [794]
TUSC2 TTJ8O14 Strong Biomarker [795]
TYK2 TTBYWP2 Strong Biomarker [796]
TYRP1 TTFRV98 Strong Biomarker [789]
UBE3A TTUZX6V Strong Biomarker [797]
UGT1A1 TT34ZAF Strong Genetic Variation [798]
ULK1 TT4D7MJ Strong Biomarker [799]
USP10 TT5IH09 Strong Altered Expression [800]
UTS2 TTERU0T Strong Biomarker [801]
UTS2R TTW5UDX Strong Biomarker [801]
VCAM1 TTHCEF6 Strong Biomarker [802]
VKORC1 TTEUC8H Strong Biomarker [803]
WAS TTE8T73 Strong Biomarker [804]
WNT5A TTKG7F8 Strong Biomarker [805]
WNT7A TT8NARC Strong Biomarker [806]
WRN TT2H5WQ Strong Genetic Variation [807]
WT1 TTZ8UT4 Strong Biomarker [808]
XDH TT7RJY8 Strong Altered Expression [809]
ZFP36L1 TT8QVJO Strong Biomarker [810]
PREPL TT3HYDO Definitive Genetic Variation [811]
------------------------------------------------------------------------------------
⏷ Show the Full List of 719 DTT(s)
This Disease Is Related to 24 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC25A19 DTT82QK Limited Biomarker [812]
ABCC5 DTYVM24 moderate Biomarker [813]
ABCC11 DTWN7FC Strong Altered Expression [294]
ABCC6 DT582KR Strong Biomarker [814]
ATP10A DTTQ8WI Strong Biomarker [815]
SLC16A7 DTLT3UG Strong Biomarker [154]
SLC24A3 DTO18LP Strong Altered Expression [816]
SLC25A3 DTCRIWV Strong Altered Expression [817]
SLC27A1 DTKDTML Strong Altered Expression [818]
SLC27A2 DTXK9WA Strong Altered Expression [819]
SLC27A5 DT0TQS3 Strong Biomarker [385]
SLC27A6 DTG4CWJ Strong Altered Expression [820]
SLC2A2 DTUJPOL Strong Altered Expression [821]
SLC2A3 DT9SQ3L Strong Biomarker [822]
SLC2A5 DTOR02F Strong Altered Expression [823]
SLC30A10 DTYBI73 Strong Biomarker [727]
SLC35B4 DTMALXP Strong Biomarker [824]
SLC35D3 DT63MZQ Strong Genetic Variation [425]
SLC39A13 DTOTKBS Strong Biomarker [825]
SLC45A2 DTNCJAT Strong Genetic Variation [340]
SLC4A4 DTWDEIL Strong Biomarker [826]
SLC5A11 DT2CAPQ Strong Biomarker [827]
SLC9A6 DTN0JXW Strong Genetic Variation [828]
SLC35A1 DTVZIRG Definitive Biomarker [829]
------------------------------------------------------------------------------------
⏷ Show the Full List of 24 DTP(s)
This Disease Is Related to 55 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
PON3 DETXQZ1 Limited Biomarker [830]
PSAT1 DEBS17P Limited Biomarker [618]
PTGDS DER3H9C Limited Biomarker [831]
SULT2A1 DE0P6LK Limited Biomarker [832]
GSTT1 DE3PKUG Disputed Biomarker [833]
CYP4F3 DEFCMPI moderate Altered Expression [834]
DHRS9 DEGTU5I moderate Altered Expression [263]
MAT2B DEKF1OH moderate Biomarker [291]
MTRR DE6NIY9 moderate Genetic Variation [835]
ACP3 DEDW5H6 Strong Biomarker [795]
ACP5 DESITDW Strong Biomarker [154]
ACSS2 DEE76VW Strong Genetic Variation [836]
ADH1B DEEN9RD Strong Biomarker [837]
AKR1C2 DEOY5ZM Strong Altered Expression [838]
AS3MT DE9KJP3 Strong Biomarker [839]
BAAT DERA3OF Strong Altered Expression [840]
CEPT1 DEL87ZT Strong Biomarker [841]
CES2 DETHCPD Strong Biomarker [842]
CHDH DEAHED0 Strong Biomarker [843]
CHST3 DEQIZP2 Strong Biomarker [844]
CYB5A DE9A2LB Strong Biomarker [154]
CYP26B1 DEZT8FM Strong Biomarker [154]
CYP27A1 DEBS639 Strong Altered Expression [845]
CYP4F2 DE3GT9C Strong Biomarker [846]
DCXR DE3FEV8 Strong Biomarker [154]
DHRS3 DEXPVUN Strong Biomarker [847]
FADS1 DE05S8C Strong Biomarker [848]
FARS2 DE0WGR8 Strong Genetic Variation [676]
FMO3 DEP76YL Strong Biomarker [849]
GLDC DEIN8FB Strong Altered Expression [850]
GSTA4 DEH7XYP Strong Altered Expression [851]
GSTO2 DEHMPZR Strong Genetic Variation [852]
HIF1AN DEY1CBW Strong Biomarker [853]
HK1 DEDMAGE Strong Biomarker [854]
ME1 DE97WM8 Strong Biomarker [855]
MSMO1 DE5FUD0 Strong Altered Expression [856]
MSRA DEU2ZBY Strong Genetic Variation [857]
MT2A DEFKGT7 Strong Altered Expression [858]
NNMT DECVGJ3 Strong Biomarker [859]
NT5C2 DE1DOKJ Strong Biomarker [860]
PER1 DE9HF0I Strong Biomarker [861]
SAT1 DEMWO83 Strong Biomarker [862]
SCLY DEH4TD6 Strong Genetic Variation [863]
SI DE5EO4Y Strong Altered Expression [593]
SULT1A1 DEYWLRK Strong Genetic Variation [864]
SULT1E1 DESTKG6 Strong Altered Expression [865]
UGT1A10 DEL5N6Y Strong Genetic Variation [798]
UGT1A3 DEF2WXN Strong Genetic Variation [798]
UGT1A4 DELOY3P Strong Genetic Variation [798]
UGT1A5 DEPF954 Strong Genetic Variation [798]
UGT1A6 DESD26P Strong Genetic Variation [798]
UGT1A7 DEZO4N3 Strong Genetic Variation [798]
UGT1A8 DE2GB8N Strong Genetic Variation [798]
UGT1A9 DE85D2P Strong Genetic Variation [798]
VKORC1L1 DERQV72 Strong Genetic Variation [866]
------------------------------------------------------------------------------------
⏷ Show the Full List of 55 DME(s)
This Disease Is Related to 978 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AACS OTGGPR6J Limited Biomarker [867]
ACKR2 OTWYY14H Limited Altered Expression [868]
ACVR1C OTOTYERF Limited Biomarker [869]
ADARB1 OTGKSZEV Limited Biomarker [870]
ADCY3 OTGOQM6B Limited Biomarker [871]
APOBEC1 OTY8QX2R Limited Biomarker [872]
APOC1 OTA58CED Limited Biomarker [873]
ARID1A OTRWDV3P Limited Biomarker [546]
ARRDC3 OTAKW7R9 Limited Biomarker [874]
ASAH1 OT1DNGXL Limited Biomarker [875]
BCAR1 OTKT2C2N Limited Genetic Variation [169]
BEST1 OTWHE1ZC Limited Biomarker [173]
BMS1 OTEGQ8ZO Limited Biomarker [876]
BNIP3 OT4SO7J4 Limited Biomarker [877]
C1QL3 OT4TZH3J Limited Altered Expression [878]
C1QTNF6 OT57EPQC Limited Biomarker [879]
CADM1 OTRWG9QS Limited Biomarker [853]
CAPN5 OTQ8QM7K Limited Genetic Variation [880]
CAV2 OT1FGRQX Limited Biomarker [881]
CCN3 OTOW5YL4 Limited Altered Expression [882]
CD1D OT3ROU4J Limited Biomarker [883]
CEACAM8 OTLL9WWO Limited Biomarker [884]
CERS6 OTOP4GV1 Limited Biomarker [885]
CISH OT8T5NYL Limited Altered Expression [478]
CPT1A OTI862QH Limited Biomarker [886]
CTNND1 OTUMPSHR Limited Genetic Variation [169]
CYBA OT16N9ZO Limited Altered Expression [887]
CYP2W1 OTXSB1AE Limited Genetic Variation [888]
DDT OTF5HTYL Limited Biomarker [889]
DEFB1 OT5SV0E4 Limited Biomarker [890]
DENR OTXP9HOY Limited Biomarker [891]
DOC2B OTRUMZ8C Limited Biomarker [892]
EHD1 OTDMEKLV Limited Biomarker [893]
ETV3 OTEN03BM Limited Biomarker [894]
FADD OTV7GFHH Limited Biomarker [895]
FAIM2 OT6QINVO Limited Genetic Variation [854]
FETUB OT7V07NI Limited Biomarker [526]
FLVCR1 OT9XCFOC Limited Altered Expression [896]
FSTL1 OT6KEZUD Limited Altered Expression [897]
FTSJ3 OT3J8P0B Limited Biomarker [898]
GALNT2 OTZZ5386 Limited Altered Expression [899]
GDF11 OTOSNMND Limited Biomarker [900]
GEMIN5 OTSF03K2 Limited Biomarker [901]
GNAS OTMH8BKJ Limited Biomarker [902]
GPAM OTR1XD9B Limited Biomarker [903]
GPRC5B OTF3S5E3 Limited Genetic Variation [374]
GUCA2B OTZERX04 Limited Altered Expression [502]
HIF3A OTPWAAMC Limited Biomarker [904]
HSPA12A OTFOCDD6 Limited Biomarker [905]
IKBKE OT5VYOSM Limited Altered Expression [906]
IL6ST OT1N9C70 Limited Biomarker [907]
INSIG1 OTZF5X1D Limited Genetic Variation [908]
IP6K1 OTKS4P2T Limited Biomarker [909]
IRF5 OT8SIIAP Limited Altered Expression [910]
IRF6 OTKJ44EV Limited Biomarker [911]
KLF15 OTGMQMVR Limited Biomarker [912]
LCE1C OTQY73YS Limited Genetic Variation [913]
LEAP2 OTUOPIS5 Limited Biomarker [914]
LPIN2 OTRRTMXX Limited Biomarker [915]
LRP1B OT4YZG2N Limited Biomarker [916]
LRPPRC OTXSK5LP Limited Biomarker [907]
LRRC8A OT23OE7H Limited Biomarker [917]
LRRFIP1 OTN7XAUD Limited Biomarker [918]
MED13 OTP5LEJE Limited Altered Expression [919]
MIP OTEBLU3E Limited Biomarker [920]
MLKL OTDSLC81 Limited Biomarker [921]
MRAP2 OTCQS7DB Limited Genetic Variation [922]
MSC OTBRPZL5 Limited Biomarker [923]
MYOD1 OTV2S79X Limited Biomarker [924]
MYOG OTPLJKFA Limited Biomarker [925]
NCF2 OTAUW7L2 Limited Biomarker [926]
NDN OTYBYJ82 Limited Biomarker [927]
NDUFAB1 OTF906UR Limited Biomarker [276]
NDUFB6 OTIXNT91 Limited Biomarker [928]
NHLH2 OT88N84O Limited Biomarker [929]
NOCT OTVSYP2D Limited Altered Expression [930]
NOX1 OTZPJQCC Limited Biomarker [616]
NPC1 OTRIPICX Limited Biomarker [931]
NR5A1 OTOULYR4 Limited Genetic Variation [932]
NRIP1 OTIZOJQV Limited Genetic Variation [933]
NUCKS1 OTL4VJC5 Limited Altered Expression [934]
OGT OT1Z1ZXE Limited Altered Expression [935]
OXCT1 OT536PE7 Limited Biomarker [867]
PC OT6O0V51 Limited Biomarker [936]
PCSK1N OT7ZRW2F Limited Biomarker [937]
PDCD4 OTZ6NXUX Limited Altered Expression [938]
PER2 OTU2B1DJ Limited Genetic Variation [939]
PHPT1 OTFYWNFX Limited Biomarker [875]
PIK3R1 OT5BZ1J9 Limited Biomarker [940]
PLCB2 OTPAHDGO Limited Altered Expression [941]
PLEK OTB73XXA Limited Biomarker [942]
PLSCR3 OTJ6K2XJ Limited Biomarker [943]
PNOC OTJEAADN Limited Biomarker [944]
PTBP2 OTF4S7NE Limited Altered Expression [945]
PTPRU OTHDO0QG Limited Altered Expression [946]
PYCARD OT67RON3 Limited Altered Expression [754]
RAPGEF5 OT53VS75 Limited Biomarker [947]
RLN3 OTQSQMUQ Limited Genetic Variation [222]
RMC1 OT7K8MTJ Limited Altered Expression [948]
RSC1A1 OT54EM29 Limited Biomarker [949]
RYR2 OT0PF19E Limited Biomarker [950]
SELENOP OT02B8IR Limited Biomarker [951]
SEMA3C OTEGUY7F Limited Biomarker [952]
SEMA3E OTD4S36H Limited Biomarker [952]
SEMA3G OTBLVF8V Limited Biomarker [953]
SERPINA12 OTS1E6IP Limited Biomarker [954]
SFTPA1 OT87XL1U Limited Biomarker [955]
SFTPB OTOHS07E Limited Biomarker [955]
SIT1 OT7MDF09 Limited Biomarker [956]
SORBS1 OTWH8762 Limited Biomarker [957]
SPAG8 OTZC5XP9 Limited Altered Expression [958]
SPRED2 OTUX685J Limited Biomarker [959]
STAT4 OTAK3VFR Limited Therapeutic [960]
STAU1 OTTR5311 Limited Genetic Variation [901]
STK11 OT1YZSP3 Limited Biomarker [961]
TAFA5 OT2SWBT6 Limited Altered Expression [962]
TAS2R38 OTX5MM36 Limited Biomarker [963]
TFEB OTJUJJQY Limited Biomarker [964]
THRAP3 OTG25JOG Limited Biomarker [965]
THY1 OTVONVTB Limited Biomarker [966]
TLE3 OTR9PH95 Limited Biomarker [967]
ATP4B OTIP2EYJ Disputed Therapeutic [968]
ATP5F1D OTXTAG2V Disputed Therapeutic [969]
FAM3A OTK1X62Z Disputed Biomarker [970]
KIFBP OT1XADKG Disputed Biomarker [971]
AFF4 OTTL5Y8R moderate Genetic Variation [972]
AIM2 OT86QUI8 moderate Biomarker [973]
ANGPTL5 OTC6AFVO moderate Altered Expression [974]
ANGPTL6 OTOQ5W67 moderate Biomarker [975]
APLP2 OTTFE53M moderate Biomarker [976]
APPL1 OT8VR95S moderate Biomarker [190]
ARL13B OT9PYPV1 moderate Biomarker [977]
ARL15 OT00YSWZ moderate Biomarker [978]
ARSD OTAHW9M8 moderate Biomarker [979]
ATG16L1 OTEOYC5D moderate Biomarker [980]
ATP2A3 OTFYDEES moderate Biomarker [981]
B4GALT5 OTHMZY12 moderate Altered Expression [982]
BRAP OTB7BAFQ moderate Genetic Variation [983]
C1QTNF3 OTOJMWW0 moderate Altered Expression [984]
CAND2 OTOMOG3R moderate Biomarker [985]
CCDC57 OTSLDWUQ moderate Biomarker [412]
CCL14 OT8QETQU moderate Biomarker [986]
CERS5 OT5A2DNI moderate Biomarker [987]
CILP2 OTAFSWG1 moderate Altered Expression [988]
CNTN3 OTC1274J moderate Biomarker [989]
CPN2 OTYOYP14 moderate Biomarker [259]
CPT1C OT8F1MBF moderate Altered Expression [990]
CREBRF OT2GK1HI moderate Genetic Variation [991]
CSTA OT1K68KE moderate Altered Expression [992]
CTRL OTB6NA5O moderate Biomarker [993]
CXCL14 OTM189TA moderate Biomarker [994]
CYTB OTAHB98A moderate Genetic Variation [995]
DPT OTINRFC7 moderate Genetic Variation [289]
DUSP22 OTEZ3U85 moderate Biomarker [996]
ERFE OTSES1HA moderate Biomarker [997]
ETV5 OTE2OBM4 moderate Genetic Variation [998]
EXOC4 OT5EWXAN moderate Biomarker [999]
FAM13A OTZ6GN0Q moderate Biomarker [1000]
FLNC OT3F8J6Y moderate Altered Expression [1001]
FOXA2 OTJOCVOY moderate Altered Expression [1002]
FZD5 OTXFFY56 moderate Altered Expression [805]
GABPB1 OTEXDEJN moderate Genetic Variation [1003]
GLS2 OT08MSHL moderate Biomarker [1004]
GOT2 OT6XBWN0 moderate Biomarker [1005]
GPX4 OTRAFFX2 moderate Altered Expression [1006]
ID3 OTUULW5Z moderate Biomarker [1007]
IMMP2L OT9WGAFD moderate Biomarker [1008]
IMPACT OTQ923OB moderate Biomarker [434]
INSL5 OTLUI3PV moderate Biomarker [1009]
IRF7 OTC1A2PQ moderate Altered Expression [850]
IRX5 OT05J514 moderate Altered Expression [329]
KBTBD11 OTBOY3WH moderate Biomarker [1010]
KCNE2 OTUO214Y moderate Genetic Variation [1011]
KCTD7 OTRU3EOK moderate Genetic Variation [1012]
KMT2B OTMMAZQX moderate Biomarker [797]
KSR2 OTSMUL59 moderate Genetic Variation [1013]
LIPC OTZY5SC9 moderate Biomarker [1014]
LTBP3 OTME98V7 moderate Biomarker [1015]
LUM OTSRC874 moderate Biomarker [1016]
MAGEE1 OTOQQO2X moderate Biomarker [267]
MAP2K4 OTZPZX11 moderate Biomarker [1017]
MARCHF8 OTH7PNN2 moderate Biomarker [1018]
MARK4 OT6Z2TGV moderate Biomarker [1019]
MBOAT7 OTHRCBLK moderate Genetic Variation [1020]
MFN2 OTPYN8A3 moderate Biomarker [1021]
MFSD2A OTVG1VG0 moderate Biomarker [1022]
MLXIP OT30UNI7 moderate Biomarker [1018]
MOGS OT99MBGB moderate Biomarker [355]
MSN OTZJ4J6G moderate Biomarker [1023]
MSS51 OTDWY1RO moderate Biomarker [1024]
MT1B OTUA4FFH moderate Biomarker [602]
MYLIP OTL0PFGV moderate Biomarker [1018]
NAA10 OTYB9R6I moderate Altered Expression [1025]
NABP2 OTQU8081 moderate Genetic Variation [1026]
ND1 OTCLGIXV moderate Biomarker [1027]
NFAT5 OTKIE59S moderate Biomarker [1028]
NLRC4 OTAIA3NA moderate Altered Expression [1029]
NMB OT4NLN6H moderate Genetic Variation [1030]
NMBR OTBJEGPN moderate Biomarker [1031]
NMU OTW9X7BQ moderate Biomarker [1032]
NOX3 OT0FFJH8 moderate Biomarker [1033]
OR10A4 OTYYB8SY moderate Biomarker [1034]
P4HB OTTYNYPF moderate Biomarker [1035]
PARD3 OTH5BPLO moderate Biomarker [264]
PERM1 OTZJW04C moderate Altered Expression [1036]
PHACTR1 OTAMPX9V moderate Genetic Variation [1011]
PHETA2 OTR0Z4U5 moderate Altered Expression [1037]
PIEZO1 OTBG1FU4 moderate Biomarker [1038]
PKHD1 OTAH8SMF moderate Genetic Variation [1039]
PLAAT2 OTI5RMWB moderate Altered Expression [1040]
PM20D1 OTXXNQ5K moderate Biomarker [1041]
PMAIP1 OTXEE550 moderate Genetic Variation [1011]
POC1A OTXAG4PL moderate Biomarker [1017]
PPP1R13L OTNCPLWE moderate Biomarker [477]
PPP1R14A OTQODWZB moderate Altered Expression [1042]
PPP1R3B OTVCRXEZ moderate Genetic Variation [1043]
PVALB OTZW1WVQ moderate Biomarker [1044]
REEP5 OTZU4TJI moderate Biomarker [279]
RETREG1 OTYOSLZX moderate Altered Expression [1045]
RND3 OTXMXPIH moderate Altered Expression [1046]
RNF41 OTN1DQOY moderate Biomarker [1047]
S100A16 OT3ERKQI moderate Altered Expression [1048]
SAGE1 OT4H6FFA moderate Biomarker [1049]
SCARB2 OTN929M8 moderate Altered Expression [1050]
SCRN2 OTSG9EUS moderate Altered Expression [1037]
SDS OT5WTJ2M moderate Biomarker [1051]
SEL1L OTC0FB7T moderate Biomarker [1052]
SELENOW OTVSKPAN moderate Biomarker [1053]
SPPL3 OT2HLJF6 moderate Biomarker [1008]
SPSB1 OTGY26U4 moderate Genetic Variation [1026]
SYNPO OTICDJAB moderate Biomarker [1054]
TAPT1 OT3Z51KH moderate Biomarker [287]
TFAP2B OTR1T8E9 moderate Genetic Variation [1055]
TFDP1 OT6RZ7VT moderate Biomarker [279]
TFF3 OTJJDRTU moderate Altered Expression [1056]
TRAM1 OT3I0H8E moderate Genetic Variation [289]
A1CF OTJBKFA1 Strong Biomarker [1057]
A2M OTFTX90K Strong Biomarker [1058]
AAAS OTJT9T23 Strong Biomarker [1059]
ABHD15 OTG98AB1 Strong Biomarker [1060]
ABHD5 OTY829Z3 Strong Biomarker [1061]
ACACA OT5CQPZY Strong Biomarker [876]
ACAD8 OT3JI5GB Strong Biomarker [1062]
ACADM OTA4P0FC Strong Biomarker [154]
ACAN OTUOCW8K Strong Biomarker [1063]
ACAT2 OTZ092ZJ Strong Altered Expression [1064]
ACCS OTHIHI9D Strong Genetic Variation [836]
ACOT11 OTGPB0SM Strong Biomarker [1065]
ACSL1 OTB06ESI Strong Altered Expression [401]
ACSL5 OT3L9XO3 Strong Genetic Variation [1066]
ACSM3 OT0AE1IV Strong Genetic Variation [1067]
ADA2 OTGCV24S Strong Genetic Variation [1068]
ADAM11 OTPTVW5W Strong Genetic Variation [369]
ADAM12 OTZKOTDB Strong Genetic Variation [380]
ADAM19 OTH88TXU Strong Biomarker [1069]
ADAM28 OT3GBVHL Strong Altered Expression [1070]
ADCY10 OTYSTB0R Strong Biomarker [504]
ADCY8 OTR1WCZX Strong Biomarker [1071]
ADCY9 OT1IZT5K Strong Genetic Variation [1072]
ADGRV1 OTLVXHHP Strong Genetic Variation [1073]
ADIPOR1 OT65ZFZN Strong Altered Expression [1074]
AGAP2 OTEYO9TM Strong Altered Expression [438]
AHI1 OT8K2YWY Strong Biomarker [1075]
AHRR OTSJ12W6 Strong Posttranslational Modification [1076]
AHSA1 OTC7AFHT Strong Altered Expression [266]
AIDA OTMRLWGT Strong Biomarker [1077]
AIRE OTA7G1Y1 Strong Biomarker [1078]
AKAP1 OTIIB2JB Strong Biomarker [623]
AKAP13 OTOZAR14 Strong Altered Expression [1079]
ALDH1L1 OT15HOJX Strong Biomarker [154]
ALDH6A1 OT8LCZCT Strong Biomarker [154]
ALMS1 OTW66JKS Strong Biomarker [1080]
ALOXE3 OT76J52A Strong Altered Expression [1081]
ALPK1 OTBW6SGD Strong Genetic Variation [1082]
AMBP OTLU8GU8 Strong Biomarker [1083]
AMH OT5FH4BD Strong Altered Expression [1084]
AMPD1 OTU17BCI Strong Genetic Variation [1085]
AMY2B OTG93YV0 Strong Genetic Variation [317]
ANGPTL2 OTB6JG41 Strong Biomarker [1086]
ANK2 OTWB4R1Y Strong Biomarker [1087]
ANKH OTCN25R5 Strong Biomarker [1088]
ANKK1 OT0OM1O0 Strong Genetic Variation [1089]
ANKRD26 OT2ENKKV Strong Posttranslational Modification [1090]
ANOS1 OTZJT4KN Strong Biomarker [487]
ANXA6 OT9KIQ0Y Strong Altered Expression [1091]
AP3S2 OTN8P9OE Strong Biomarker [1092]
APCDD1 OTV9AD0L Strong Biomarker [383]
APH1A OT97F1TU Strong Altered Expression [1093]
APOA5 OTEVKLVA Strong Biomarker [1094]
APOD OTT77XW8 Strong Altered Expression [1095]
APOM OTI3FQQC Strong Altered Expression [1096]
APOO OTAHHRGZ Strong Genetic Variation [1097]
ARHGAP21 OT6XY8Y9 Strong Biomarker [281]
ARID2 OTIRJXWM Strong Biomarker [1098]
ARL6IP5 OTYZ6BEQ Strong Biomarker [1099]
ARNT2 OTAQD3YV Strong Biomarker [1100]
ARR3 OTRZ00CH Strong Biomarker [217]
ARTN OTWIWGL6 Strong Genetic Variation [1101]
ASAH2 OT47TIF3 Strong Genetic Variation [1102]
ASAP1 OT4DLRYY Strong Biomarker [795]
ASAP2 OTGEXULW Strong Biomarker [795]
ASCL1 OTI4X44G Strong Biomarker [1103]
ASPG OT5E2EKR Strong Biomarker [1104]
ASPM OTKXQMNA Strong Altered Expression [335]
ASPSCR1 OTXTOD10 Strong Biomarker [1105]
ATF6 OTAFHAVI Strong Biomarker [1106]
ATP10D OT3JPE4H Strong Biomarker [1107]
ATP5F1A OT3FZDLX Strong Biomarker [1108]
ATP5F1B OTLFZUQK Strong Altered Expression [1109]
ATP5F1E OTMPLAIS Strong Genetic Variation [1110]
ATP6 OTPHOGLX Strong Genetic Variation [1111]
ATP6AP2 OT0IABVV Strong Biomarker [1112]
ATP8B3 OTZOGEJO Strong Biomarker [815]
ATPAF1 OTG1V44F Strong Biomarker [154]
ATRN OTTCLOPV Strong Biomarker [1113]
BAD OT63ERYM Strong Genetic Variation [710]
BAMBI OTCEJ8W5 Strong Biomarker [1114]
BBS1 OTXSXB1K Strong Genetic Variation [1115]
BBS10 OTL1TTWX Strong Biomarker [1116]
BBS2 OTPF9JIB Strong Genetic Variation [1117]
BBS4 OT0D3JC0 Strong Biomarker [1118]
BBS9 OT23V9YF Strong Genetic Variation [1119]
BCAP31 OTKSACR4 Strong Biomarker [1120]
BCL2L11 OTNQQWFJ Strong Biomarker [1121]
BCS1L OT5PY5CY Strong Biomarker [1122]
BHLHE40 OTITX14U Strong Biomarker [1123]
BHMT OTYB6PXZ Strong Genetic Variation [1124]
BID OTOSHSHU Strong Biomarker [1125]
BMPR1A OTQOA4ZH Strong Biomarker [1126]
BRWD3 OT3BM9B0 Strong Biomarker [1127]
BUB1B OT8KME51 Strong Biomarker [1128]
C1QTNF1 OT7I7KHC Strong Biomarker [1129]
C1QTNF12 OTFAIQHR Strong Altered Expression [1130]
C1QTNF5 OTLKU5I2 Strong Biomarker [1131]
C1QTNF7 OTN1IFTK Strong Biomarker [1132]
C1QTNF9 OTLI3VA3 Strong Biomarker [1133]
C2CD5 OTI495RD Strong Biomarker [1134]
CADM2 OT45PVKC Strong Genetic Variation [1135]
CALD1 OTNJKJ6Q Strong Genetic Variation [1136]
CAMK2A OTJGX19T Strong Genetic Variation [1137]
CAPN3 OTCHG3YK Strong Biomarker [362]
CAPNS1 OT95EBBD Strong Biomarker [599]
CARD9 OTJ81AWD Strong Biomarker [1138]
CARF OTWE0T6Q Strong Biomarker [1139]
CAST OTBXZZGF Strong Biomarker [1140]
CAVIN1 OTFO915U Strong Biomarker [1141]
CBLL2 OTB4AD3V Strong Biomarker [1142]
CCAR2 OTLUDG5T Strong Biomarker [1143]
CCDC77 OTQQT2IC Strong Genetic Variation [676]
CCDC80 OTOZSYEM Strong Biomarker [1144]
CCHCR1 OT22C116 Strong Genetic Variation [1145]
CCL18 OT7JYSK9 Strong Biomarker [1146]
CCL19 OTQ2UJMH Strong Altered Expression [1147]
CCL27 OTUZYC61 Strong Biomarker [1148]
CCL28 OTY6XNQ7 Strong Genetic Variation [1149]
CCL4 OT6B8P25 Strong Genetic Variation [1150]
CCL7 OTDIS99H Strong Biomarker [1151]
CCL8 OTCTWYN8 Strong Altered Expression [1152]
CCN4 OT69BER9 Strong Altered Expression [1153]
CCN5 OTADU8JJ Strong Biomarker [1154]
CD180 OTITK5E6 Strong Biomarker [1155]
CD48 OT83ZNPP Strong Biomarker [1156]
CD5L OTPY4WQR Strong Biomarker [165]
CD68 OTOYEY3J Strong Biomarker [376]
CD79A OTOJC8DV Strong Genetic Variation [1157]
CD81 OTQFXNAZ Strong Altered Expression [1158]
CD8A OTDWQJXK Strong Biomarker [355]
CDAN1 OTCVZRG6 Strong Genetic Variation [1159]
CDH13 OTD2CYM5 Strong Altered Expression [1160]
CDKAL1 OTA0SGNE Strong Genetic Variation [1161]
CEBPD OTNBIPMY Strong Altered Expression [1162]
CELF1 OT6JQ5RS Strong Genetic Variation [374]
CELF4 OT4FS4F5 Strong Biomarker [1163]
CENPJ OTZCQZN5 Strong Altered Expression [1164]
CEP19 OTL2WXOR Strong Genetic Variation [1165]
CFAP410 OTJ94J99 Strong Genetic Variation [1166]
CFAP61 OTF1LAS4 Strong Altered Expression [816]
CFAP97 OT0RSQO4 Strong Biomarker [1167]
CGRRF1 OTLMNRCL Strong Biomarker [1168]
CHAF1A OTXSSY4H Strong Biomarker [1169]
CHD2 OTRKL6YC Strong Genetic Variation [692]
CHD8 OTS7A6AF Strong Genetic Variation [1170]
CHGA OTXYX5JH Strong Biomarker [829]
CHPT1 OT4FJ0K3 Strong Biomarker [886]
CHRNA3 OTCZQY1U Strong Genetic Variation [392]
CIDEA OTDUTSOV Strong Altered Expression [1171]
CIDEC OTMDZ56K Strong Biomarker [1172]
CISD1 OT0MTVGF Strong Altered Expression [1173]
CISD2 OTVS7S2H Strong Biomarker [1174]
CITED2 OT812TV7 Strong Biomarker [1175]
CLDN10 OT2CVAKY Strong Biomarker [1176]
CLEC7A OTRTBH27 Strong Biomarker [1177]
CLTA OTLHOXMQ Strong Genetic Variation [503]
CMAS OTFQJG3C Strong Genetic Variation [1178]
CMIP OTZN8Z4A Strong Genetic Variation [1179]
CNBP OTTGM9NK Strong Biomarker [1180]
CNDP1 OTOYSQG7 Strong Genetic Variation [1181]
CNDP2 OTJR9436 Strong Genetic Variation [1181]
CNTN4 OTULXVE0 Strong Biomarker [1182]
CNTN5 OTWU5FLZ Strong Biomarker [1183]
COL12A1 OTHLTV53 Strong Altered Expression [826]
COL25A1 OT7M23Z9 Strong Biomarker [1184]
COL6A1 OTYKSCOB Strong Biomarker [1185]
COL9A3 OTCUJOEK Strong Genetic Variation [790]
COMP OTS2FPMI Strong Biomarker [1186]
COPA OTZ1DTXU Strong Biomarker [1187]
CORT OTX3GUHB Strong Biomarker [1188]
COX4I1 OTU0FC24 Strong Biomarker [1189]
COX7C OTREWSBF Strong Biomarker [154]
COX8A OTU0NR39 Strong Genetic Variation [1190]
CPNE5 OTU882I6 Strong Genetic Variation [1191]
CPT2 OTIN6G20 Strong Biomarker [886]
CRABP1 OTISDG5X Strong Biomarker [1192]
CREB3L4 OTSGQGT2 Strong Altered Expression [438]
CREG1 OTRHJ8HK Strong Biomarker [1193]
CREM OTJIJ5AL Strong Altered Expression [1194]
CRISP2 OT8HLTV5 Strong Biomarker [1195]
CRTC3 OTVIGVUW Strong Biomarker [1196]
CRYBG1 OTIPDI15 Strong Genetic Variation [340]
CUL4B OT2QX4DO Strong Biomarker [1197]
CXADR OT9ZP02A Strong Biomarker [217]
CXCL16 OTD49T9R Strong Genetic Variation [1198]
CXCL5 OTZOUPCA Strong Biomarker [1199]
CYCS OTBFALJD Strong Biomarker [1200]
CYP2D7 OTYJTL3S Strong Genetic Variation [1201]
DACH1 OTMKNAGG Strong Biomarker [1202]
DACT1 OT19Z704 Strong Biomarker [742]
DAPK2 OTWODUQG Strong Biomarker [891]
DBI OT884QY9 Strong Genetic Variation [1203]
DCDC2 OTSUFH1H Strong Biomarker [1122]
DCP1B OTX7PHCI Strong Genetic Variation [1204]
DCTN4 OTM7C943 Strong Biomarker [552]
DDAH2 OT8Q40G2 Strong Genetic Variation [1205]
DDHD2 OTUP0WHF Strong CausalMutation [1206]
DDIT3 OTI8YKKE Strong Biomarker [1106]
DECR1 OTCDIR6X Strong Altered Expression [805]
DENND1A OTONDAA0 Strong Genetic Variation [1207]
DESI1 OTFNIW98 Strong Altered Expression [1208]
DGKE OTWS86AS Strong Genetic Variation [1209]
DGKG OTBL32T3 Strong Genetic Variation [1072]
DHX40 OTOL02QN Strong Biomarker [641]
DMRTA1 OTRZY9E9 Strong Genetic Variation [1210]
DNAH8 OTGES2OU Strong Biomarker [1211]
DNAJB3 OTODJZY9 Strong Biomarker [1212]
DNAJB9 OT38EQT6 Strong Biomarker [1213]
DNAJC27 OTJRPCUR Strong Biomarker [1214]
DNAJC6 OT1P6ZIE Strong Genetic Variation [1215]
DNM3 OTDMUGCR Strong Genetic Variation [583]
DOCK2 OTZTS3PA Strong Biomarker [1216]
DOCK5 OT63I0CL Strong Biomarker [1217]
DOK5 OT2XWUPN Strong Biomarker [1218]
DPYSL4 OT3SBS2S Strong Biomarker [1219]
DST OTHZBM4X Strong Biomarker [1220]
DUSP6 OT4H6RKW Strong Genetic Variation [1221]
EAF2 OTSOET5L Strong Biomarker [1222]
EBF2 OTFWZE51 Strong Biomarker [521]
ECHS1 OTS0593S Strong Biomarker [154]
ECT2 OTQDUCT6 Strong Biomarker [1098]
EDEM1 OTWHN69S Strong Altered Expression [1223]
EFNB1 OT7JJW8P Strong Biomarker [1224]
EIF2S1 OTM0GDTP Strong Biomarker [1225]
EIF2S2 OTXF0B09 Strong Biomarker [1225]
EIF2S3 OTARRES9 Strong Biomarker [1225]
EIF6 OTEXMUED Strong Altered Expression [1226]
ELN OTFSO7PG Strong Altered Expression [1227]
ELOVL5 OT375W1Z Strong Altered Expression [1228]
ELOVL6 OTB26UJJ Strong Biomarker [1229]
EMD OTR8ZANE Strong Biomarker [1230]
EML6 OTE1MUQS Strong Genetic Variation [543]
ENTPD6 OT94M6A7 Strong Biomarker [1013]
ERCC4 OTFIOPG1 Strong Genetic Variation [1231]
ERG OTOTX9VU Strong Biomarker [776]
ETFA OTXX61VZ Strong Genetic Variation [1201]
ETFDH OTOSKSFH Strong Biomarker [154]
EXOSC4 OTG4TICP Strong Genetic Variation [1232]
FAM3B OTC2S91N Strong Altered Expression [1233]
FANCB OTMZTXB5 Strong Biomarker [1234]
FAT2 OTRGT3E8 Strong Genetic Variation [1235]
FBL OTRODIE5 Strong Biomarker [1236]
FBN1 OTYCJT63 Strong Biomarker [1237]
FCGR3B OTSLSPZG Strong Biomarker [376]
FERMT2 OTZNPWWX Strong Genetic Variation [374]
FGF13 OTHNNVSG Strong Biomarker [463]
FGF5 OTQXGHBY Strong Genetic Variation [406]
FGGY OTLNEC2X Strong Biomarker [1238]
FGL1 OTT0QHQ1 Strong Biomarker [1239]
FLAD1 OTY8R02L Strong Genetic Variation [603]
FN3KRP OT9HR05S Strong Biomarker [1240]
FNDC5 OT5CSK9X Strong Altered Expression [1241]
FOXO3 OTHXQG4P Strong Biomarker [1242]
FPGT-TNNI3K OTJ6CWUN Strong Genetic Variation [1072]
FTL OTYQA8A6 Strong Biomarker [1243]
FTSJ1 OTNE7W96 Strong Biomarker [898]
FUNDC1 OTA6IVKQ Strong Biomarker [1244]
FUZ OTC427QQ Strong Biomarker [1245]
FZD4 OTGLZIE0 Strong Biomarker [356]
G0S2 OT8FL49L Strong Altered Expression [1246]
GAB2 OTBFN705 Strong Biomarker [1247]
GABPA OT9YB2SA Strong Biomarker [1248]
GABRA6 OTX4UC3O Strong Biomarker [1249]
GALP OTW25XLK Strong Biomarker [1250]
GAS7 OT0M5TNY Strong Biomarker [855]
GC OTWS63BY Strong Biomarker [1251]
GCA OTAJ7ZHG Strong Genetic Variation [1252]
GCKR OTSIWXGG Strong Genetic Variation [1253]
GDF10 OTEVXGJ7 Strong Biomarker [1254]
GFER OTVK43OK Strong Biomarker [1255]
GFI1 OT9HB9H8 Strong Altered Expression [1256]
GFPT1 OTQBDO45 Strong Biomarker [154]
GGTLC1 OTWJKUHQ Strong Genetic Variation [1257]
GH2 OT32TR4C Strong Biomarker [1258]
GHRH OT94U6MO Strong Altered Expression [1259]
GK OTK2YRA0 Strong Altered Expression [1260]
GLRA3 OTC8C2NC Strong Genetic Variation [1261]
GNA12 OT3IRZH3 Strong Biomarker [1262]
GNA13 OTVDL515 Strong Biomarker [1263]
GNAT2 OTD9Y4UH Strong Genetic Variation [1072]
GNAT3 OTS96V19 Strong Genetic Variation [1264]
GOLGA6A OTHU9MRX Strong Biomarker [1265]
GOLGB1 OT2S0GK8 Strong Biomarker [1266]
GORASP2 OTL3PLD2 Strong Biomarker [1267]
GPAT3 OTJUGPK0 Strong Biomarker [1268]
GPC4 OTUJ14DW Strong Altered Expression [1269]
GPCPD1 OTFE3RCV Strong Biomarker [1270]
GPD1L OTVLWW9T Strong Biomarker [1271]
GPIHBP1 OTDF8R2M Strong Biomarker [1272]
GPR151 OT7EACU6 Strong Biomarker [356]
GPR42 OTEB0ROY Strong Biomarker [299]
GPR50 OT0EJBM4 Strong Genetic Variation [1273]
GPR83 OT7A2FE8 Strong Biomarker [1274]
GPS2 OT065FSS Strong Altered Expression [1275]
GPX3 OT6PK94R Strong Altered Expression [1276]
GRAP2 OTS5NIZ3 Strong Altered Expression [266]
GRB14 OTFET2YM Strong Genetic Variation [1277]
GRK4 OTUU8V2S Strong Genetic Variation [720]
GRP OT8JDFNI Strong Biomarker [385]
GTF2H1 OTCRXC6B Strong Biomarker [552]
GTF3A OTVROUVQ Strong Biomarker [1278]
GUCA2A OTUSF75G Strong Biomarker [1279]
H2AX OT18UX57 Strong Biomarker [1280]
H6PD OTO7TNDD Strong Altered Expression [1281]
HADH OTJDOL20 Strong Biomarker [1282]
HAS2 OTTD3PAL Strong Altered Expression [1283]
HAUS1 OTBML7XD Strong Biomarker [1284]
HELZ2 OTM6HVO6 Strong Biomarker [1285]
HESX1 OT5E2Z4G Strong Biomarker [487]
HHEX OTLIUVYX Strong Biomarker [1286]
HHIP OT77RQYS Strong Biomarker [1287]
HID1 OTVJIFSU Strong Altered Expression [1288]
HJV OT4235J2 Strong Biomarker [1289]
HLA-DRB3 OT5PM9N7 Strong Altered Expression [1290]
HMG20A OTASVPIF Strong Genetic Variation [1277]
HNRNPH1 OTFRWOLM Strong Biomarker [509]
HOOK2 OTPO4NQV Strong Biomarker [1291]
HOPX OTBSR6C9 Strong Biomarker [393]
HORMAD1 OT7DR5T2 Strong Biomarker [1092]
HOXB3 OT9UC5PE Strong Genetic Variation [1082]
HOXB5 OTU74TB8 Strong Genetic Variation [634]
HOXC10 OT5WF17M Strong Biomarker [1292]
HOXC9 OT60K4M0 Strong Biomarker [1292]
HOXD13 OTWSC8TF Strong Genetic Variation [1293]
HPR OTXSC9UB Strong Biomarker [1294]
HS6ST3 OTTW9PDL Strong Genetic Variation [1072]
HSPA14 OTZCA5LK Strong Biomarker [1295]
HYOU1 OTBGBSOV Strong Biomarker [1296]
IARS1 OT9WXH5N Strong Genetic Variation [1297]
ICAM3 OTTZ5A5D Strong Biomarker [779]
IFI30 OT9DERT1 Strong Genetic Variation [1298]
IFNGR1 OTCTQBWW Strong Biomarker [1299]
IGF2BP2 OT4ZSEEE Strong Biomarker [1008]
IGFALS OTTWCZYM Strong Biomarker [1300]
IL10RA OTOX3D1D Strong Genetic Variation [371]
IL1F10 OTJAASGC Strong Biomarker [1301]
IL34 OTZ15VVK Strong Altered Expression [1302]
IL6R OTCQL07Z Strong Altered Expression [1303]
ING2 OT6H0EWF Strong Biomarker [355]
INPP5E OTJF2AZ9 Strong Therapeutic [1304]
INPPL1 OTCDAVBQ Strong Biomarker [1305]
INTU OTXB13E6 Strong Biomarker [488]
IQCK OT4QNL67 Strong Genetic Variation [374]
IRX3 OTLJ48FG Strong Genetic Variation [1306]
ITGAD OTNS69WO Strong Altered Expression [1307]
ITGAX OTOGIMHE Strong Altered Expression [1308]
ITIH5 OTP46PZM Strong Altered Expression [1309]
ITLN1 OT7ZLJVV Strong Genetic Variation [1310]
ITPRID2 OTO3JDX5 Strong Biomarker [1311]
JAKMIP3 OT4EDANR Strong Biomarker [1312]
JPH3 OTHTJO2I Strong Biomarker [1313]
KAT5 OTL7257A Strong Biomarker [1314]
KCP OTIS86DZ Strong Altered Expression [1315]
KDM4B OT5P1UPY Strong Biomarker [1316]
KIDINS220 OTLBH2MA Strong Genetic Variation [1317]
KLF13 OTMIKHZ4 Strong Biomarker [1318]
KLF14 OT8BXLBS Strong Altered Expression [1319]
KLF7 OTS3YVA0 Strong Altered Expression [1320]
KMT2D OTTVHCLY Strong Biomarker [797]
KRIT1 OT58AP1I Strong Genetic Variation [1321]
KRT18 OTVLQFIP Strong Biomarker [1322]
KRT31 OTB6RCAH Strong Genetic Variation [1323]
KRT7 OTLT3JFN Strong Biomarker [505]
LACTB OTRWGNBF Strong Biomarker [1324]
LAT2 OTWJDKIH Strong Biomarker [1325]
LCE1A OT4WBMO3 Strong Genetic Variation [1157]
LDB1 OT20EAPR Strong Biomarker [1326]
LETM1 OT8N4MRU Strong Altered Expression [1327]
LGALS12 OTNTQULB Strong Altered Expression [1328]
LGALS13 OTEV3DD7 Strong Altered Expression [1329]
LGR6 OTPZ1PWR Strong Biomarker [356]
LHFPL3 OTG1EI22 Strong Genetic Variation [1330]
LHX3 OTQ5BAJ9 Strong Altered Expression [487]
LINGO2 OT3N88Q1 Strong Genetic Variation [1331]
LITAF OTT5JX1F Strong Altered Expression [1332]
LMO3 OTR7AJHN Strong Biomarker [1333]
LPGAT1 OTN4HEJ4 Strong Biomarker [1334]
LPIN1 OTQ75KF2 Strong Biomarker [1335]
LRG1 OTLD0KWA Strong Biomarker [1336]
LRRN1 OT6MMO6L Strong Biomarker [1182]
LRRN4 OTC2T1MP Strong Genetic Variation [1337]
LSR OTR8Y32X Strong Biomarker [1338]
LUC7L3 OTKDED8A Strong Biomarker [1339]
LY86 OTTZB64A Strong Genetic Variation [1340]
LYPD4 OTYNO8BS Strong Genetic Variation [1341]
LYPLAL1 OT8F2DCV Strong Biomarker [1342]
LZTFL1 OTIEIOEW Strong Biomarker [1343]
MACROD2 OTNQCHC6 Strong Genetic Variation [1344]
MAD2L2 OT24ZO59 Strong Biomarker [1128]
MAF OT1GR3IZ Strong Genetic Variation [1345]
MAF1 OTKB0N8Q Strong Biomarker [1346]
MAGEC3 OT0KDWZN Strong Biomarker [504]
MAGED1 OT6EOLFC Strong Biomarker [1347]
MAGEE2 OTL3E0G7 Strong Biomarker [504]
MAGEL2 OTXEL4R7 Strong Genetic Variation [1348]
MAP2K3 OTI2OREX Strong Altered Expression [582]
MAP2K6 OTK13JKC Strong Biomarker [1349]
MAP4K5 OTUFGLXE Strong Genetic Variation [1350]
MAP9 OTZD5099 Strong Biomarker [1351]
MARCHF1 OTI2EYO6 Strong Altered Expression [1352]
MARCHF10 OTAYGHDM Strong Biomarker [1353]
MARK1 OTP7KL47 Strong Altered Expression [1354]
MBD2 OTUQPP0R Strong Altered Expression [1355]
MBD5 OTFHT4MO Strong Genetic Variation [1356]
MCAT OTH07FIW Strong Biomarker [396]
MCIDAS OTK1JVAH Strong Genetic Variation [1357]
MCTP2 OTFMZ8I2 Strong Biomarker [1358]
MCTS1 OT7SAOJP Strong Biomarker [396]
MCU OTQZAYWQ Strong Biomarker [1359]
MDFIC OTSRYBWZ Strong Biomarker [1360]
MED12 OTQZ4D2X Strong Genetic Variation [1361]
MEST OT8Q4U8Y Strong Biomarker [1362]
METRN OTI2645G Strong Altered Expression [1363]
METRNL OTB0DDL0 Strong Biomarker [1364]
METTL14 OT6TPQMH Strong Biomarker [1365]
METTL21C OTEMLDE6 Strong Genetic Variation [1366]
METTL3 OTSXP1M3 Strong Biomarker [1365]
MFAP2 OTMHVBTV Strong Biomarker [1367]
MFAP5 OT46VXSG Strong Biomarker [1368]
MFRP OTHY9ZA5 Strong Biomarker [1131]
MGAT3 OTXI5X4T Strong Biomarker [1369]
MIOX OTDD9G4E Strong Biomarker [1370]
MLH3 OT91PPBI Strong Biomarker [822]
MLXIPL OTR9MLLW Strong Genetic Variation [1253]
MMP19 OTLSTT2B Strong Biomarker [1371]
MMUT OTBBBV70 Strong Biomarker [154]
MOB1A OTSPBZ4Z Strong Biomarker [1372]
MOB4 OTOQRMAS Strong Biomarker [1372]
MOK OTQK7M9V Strong Biomarker [473]
MRGPRX3 OTRKCCDS Strong Biomarker [356]
MRGPRX4 OTOBHZVA Strong Biomarker [356]
MRPL33 OTA3YDH0 Strong Biomarker [1373]
MRPS22 OTIVNAJL Strong Genetic Variation [646]
MRPS30 OTDXIAGG Strong Biomarker [795]
MTHFD1 OTMKHVWC Strong Genetic Variation [1374]
MTIF3 OTPQ7FPQ Strong Genetic Variation [1375]
MTMR11 OTHL2O08 Strong Biomarker [1339]
MTMR14 OTUUEY6Q Strong Biomarker [1376]
MTMR9 OTGCBJHD Strong Genetic Variation [1377]
MTPAP OT6HQ02S Strong Biomarker [795]
MVP OTJGHJRB Strong Biomarker [1378]
MYCL OT1MFQ5U Strong Biomarker [1379]
MYDGF OT9HRPL6 Strong Altered Expression [534]
MYH6 OT3YNCH1 Strong Biomarker [605]
MYL2 OT78PC0C Strong Genetic Variation [1380]
MYT1L OTV45MAS Strong Genetic Variation [1381]
MZB1 OT071TET Strong Biomarker [1382]
NANS OTMQ2FUH Strong Biomarker [1383]
NAP1L5 OTF4Q6ZW Strong Genetic Variation [1384]
NBEAL1 OTLJ11N3 Strong Biomarker [1139]
NBEAL2 OTMCAXWR Strong Biomarker [1385]
NBR1 OTVRL7J9 Strong Biomarker [576]
NCAM2 OT8LBJN8 Strong Genetic Variation [1330]
NCOA1 OTLIUJQD Strong Altered Expression [272]
NCOA2 OTMQFPBB Strong Genetic Variation [1386]
NCOR1 OT04XNOU Strong Biomarker [1387]
NCR2 OT2H13BX Strong Biomarker [1388]
NCS1 OT6JHAWM Strong Biomarker [1389]
NDRG4 OTJBOTD8 Strong Altered Expression [1390]
NEDD4L OT1B19RU Strong Genetic Variation [1391]
NEIL1 OTHBU5DJ Strong Biomarker [1392]
NEUROD1 OTZQ7QJ2 Strong Genetic Variation [1393]
NEUROG3 OT6DIPWC Strong Biomarker [1103]
NFATC3 OTYOORME Strong Biomarker [1394]
NFE2L1 OT1QHOS2 Strong Biomarker [1395]
NFYA OTWFFOVH Strong Altered Expression [1396]
NHS OTKE8QAT Strong Biomarker [1397]
NINJ1 OTLRZ1EU Strong Genetic Variation [676]
NLGN2 OTHDYL3H Strong Genetic Variation [1398]
NLRP12 OTGR132Z Strong Biomarker [1399]
NLRP6 OTEREN4W Strong Biomarker [1400]
NNAT OTNRLO7G Strong Altered Expression [1401]
NOB1 OTW0YNSL Strong Genetic Variation [1402]
NOG OTGRHHPG Strong Genetic Variation [1403]
NPNT OTFZAO1G Strong Biomarker [1404]
NPPA OTMQNTNX Strong Genetic Variation [1405]
NPTN OTAQKSAU Strong Genetic Variation [1406]
NPVF OTIMUS0X Strong Genetic Variation [1407]
NR2C2 OTDZWVOJ Strong Biomarker [1408]
NRF1 OTOXWNV8 Strong Biomarker [1409]
NTS OTPGDNQS Strong Biomarker [1410]
NUCB2 OTHO6JWN Strong Biomarker [1411]
NUDT11 OTFDXJA1 Strong Biomarker [1078]
NUP62 OTMN63DH Strong Biomarker [552]
NUPR1 OT4FU8C0 Strong Genetic Variation [1412]
NXPH1 OTGKX860 Strong Biomarker [1413]
OGA OT7ZBWT1 Strong Biomarker [1414]
OIP5 OTI5C2DE Strong Biomarker [1415]
OLFM1 OTOYPEWW Strong Biomarker [1184]
OMG OTXA5C6L Strong Biomarker [1416]
OPN1MW OTPJ7LX4 Strong Biomarker [1266]
ORM1 OTZKSBRE Strong Altered Expression [1108]
OSBPL11 OTU2IC5O Strong Genetic Variation [1417]
OSCP1 OTZ4IFGJ Strong Biomarker [209]
OTP OTS0JN6Y Strong Genetic Variation [1418]
PACS1 OT9TMQL3 Strong Genetic Variation [1419]
PAK3 OT80M3BV Strong Biomarker [814]
PANX1 OTXPEDOK Strong Biomarker [1420]
PAPOLA OTPHD65D Strong Biomarker [795]
PAQR3 OTTKJ9Y4 Strong Biomarker [1421]
PARP9 OT7K4494 Strong Biomarker [385]
PAX6 OTOC9876 Strong Genetic Variation [1422]
PCDH9 OTX3BFV4 Strong Genetic Variation [1330]
PCK2 OTJ8LX4N Strong Genetic Variation [472]
PDAP1 OTJSWMOD Strong Biomarker [795]
PDC OT1UUVYY Strong Biomarker [1423]
PDK4 OTCMHMBZ Strong Biomarker [1424]
PEG3 OTHQW98S Strong Altered Expression [1425]
PELI3 OTCBUSKJ Strong Altered Expression [438]
PER3 OTVKYVJA Strong Biomarker [1426]
PEX1 OTQJF0V7 Strong Biomarker [1427]
PEX11A OT8MJ9CJ Strong Biomarker [1428]
PGAM5 OT6Q5M0C Strong Biomarker [1429]
PHF2 OTJCIQR2 Strong Biomarker [1430]
PHF6 OT8DXI40 Strong Genetic Variation [1431]
PHLPP1 OTIFXW8D Strong Biomarker [1432]
PIAS1 OTZVAHZI Strong Altered Expression [1433]
PIAS3 OT3TWH9R Strong Altered Expression [1433]
PICALM OTQVRPMQ Strong Genetic Variation [374]
PID1 OT5YJ7FI Strong Altered Expression [1434]
PITX3 OTE2KT8P Strong Biomarker [407]
PIWIL4 OTDA9MY0 Strong Posttranslational Modification [470]
PLA2G15 OT6VJTPA Strong Genetic Variation [836]
PLA2G2E OTGJ5XJR Strong Biomarker [1435]
PLA2G5 OTQRSKCZ Strong Biomarker [1435]
PLA2G6 OT5FL0WU Strong Altered Expression [1436]
PLAG1 OTT9AJQY Strong Biomarker [618]
PLAGL1 OTZAO900 Strong Genetic Variation [1437]
PLIN2 OTRXJ9UN Strong Genetic Variation [1438]
PLIN3 OT9ZA7MR Strong Biomarker [1439]
PLIN5 OTV8G50L Strong Genetic Variation [1440]
PLXNA1 OTN0BING Strong Biomarker [1441]
PLXNA3 OTMZIBVG Strong Biomarker [1442]
PMCH OT3D9SA4 Strong Biomarker [1443]
PNPLA1 OTUI609X Strong Genetic Variation [1444]
POC5 OTHD4FIH Strong Genetic Variation [1072]
POLD3 OTEQEFQ2 Strong Genetic Variation [1445]
POLDIP2 OT8SZSJ6 Strong Altered Expression [266]
POLE3 OTOELRF6 Strong Genetic Variation [1445]
POLG OTDUCT04 Strong CausalMutation [1446]
POLR1B OTKREU8M Strong Genetic Variation [1445]
POTEF OTV3WXYE Strong Altered Expression [1447]
POU3F2 OT30NFOC Strong Genetic Variation [1448]
PPARGC1A OTHCDQ22 Strong Altered Expression [1241]
PPIG OTZ8BTTM Strong Biomarker [1449]
PPM1L OTGGNG6M Strong Biomarker [1324]
PPP1R15A OTYG179K Strong Biomarker [1450]
PPP1R3G OTFXJK3V Strong Biomarker [1451]
PPP2R2A OT9297OG Strong Biomarker [1072]
PPP2R5C OTF7CGO2 Strong Altered Expression [1452]
PRB1 OTV0SYMD Strong Biomarker [1453]
PRDM16 OT0BGA27 Strong Biomarker [1454]
PRDM2 OT8L7CGX Strong Biomarker [1455]
PRDM4 OTD9PAZJ Strong Altered Expression [1456]
PRDM6 OTKY12D9 Strong Genetic Variation [583]
PRDX3 OTLB2WEU Strong Genetic Variation [1457]
PRKAG2 OTHTAM54 Strong Posttranslational Modification [1458]
PRLH OTJBP360 Strong Biomarker [1459]
PRLHR OT1THGOP Strong Biomarker [1460]
PRMT6 OT5V3XIN Strong Biomarker [1461]
PROK2 OT70IFEZ Strong Biomarker [1462]
PROP1 OT8GF6N8 Strong Biomarker [487]
PROS1 OTXQWNOI Strong Biomarker [618]
PROX1 OT68R6IO Strong Genetic Variation [1463]
PRRT2 OTCJUBDO Strong Biomarker [278]
PRRX1 OTTZK5G8 Strong Altered Expression [765]
PRSS55 OTXXWI5Y Strong Biomarker [1195]
PSD3 OTTN9B9O Strong Genetic Variation [1464]
PSENEN OTJ7M7G9 Strong Genetic Variation [1465]
PSG5 OTHTU98X Strong Altered Expression [1466]
PSMD9 OT6Y5CC3 Strong Biomarker [1467]
PSPC1 OTYS6WQ8 Strong Biomarker [1468]
PTER OTBYJHDG Strong Genetic Variation [1469]
PTOV1 OT94WT5X Strong Biomarker [1470]
PTPN22 OTDCNTC3 Strong Genetic Variation [673]
PTPRE OTOD5NID Strong Biomarker [1471]
PTPRF OTH5KF2D Strong Genetic Variation [1472]
PTX3 OTPXHRKU Strong Biomarker [1473]
PUM1 OTTMWP8L Strong Genetic Variation [583]
PYGO2 OTZHB2OI Strong Biomarker [1474]
QPCTL OTJD4K8A Strong Genetic Variation [1475]
QRSL1 OTJDU2UG Strong Genetic Variation [1476]
RAB18 OTNMAQLS Strong Biomarker [1477]
RAB21 OTH3WGLG Strong Biomarker [1013]
RAB4B OTTT4DY3 Strong Altered Expression [1478]
RABEP2 OTO61X27 Strong Genetic Variation [1072]
RABGEF1 OTWC3Z3R Strong Biomarker [1479]
RAMP2 OTGQXLH5 Strong Altered Expression [360]
RAMP3 OTX6XLLM Strong Biomarker [490]
RAP1A OT5RH6TI Strong Biomarker [1479]
RAPSN OTGMSWDQ Strong Genetic Variation [603]
RARRES2 OT1BJE8K Strong Biomarker [1480]
RASA2 OTL06RG2 Strong Genetic Variation [853]
RAX2 OT1HD6CF Strong Genetic Variation [166]
RBFOX1 OTFPKEL7 Strong Genetic Variation [1481]
RBM6 OTI99KAZ Strong Biomarker [1092]
RBMS1 OTD13PJN Strong Genetic Variation [1482]
RCAN1 OT1MVXC7 Strong Altered Expression [1483]
RCAN2 OTGGWTWS Strong Biomarker [1484]
RCBTB1 OTAYELI8 Strong Biomarker [1265]
REPIN1 OTVTPXNX Strong Biomarker [1485]
RFC2 OTJ9N6BD Strong Altered Expression [1486]
RFX7 OTKFNW3A Strong Biomarker [1487]
RGMB OT2DROYU Strong Biomarker [1488]
RGS14 OTYN79AG Strong Biomarker [1489]
RIN3 OT5Z6F8O Strong Genetic Variation [1490]
RNASE2 OT8Z4FNE Strong Genetic Variation [1491]
RNF19A OTKWCV80 Strong Altered Expression [266]
RNF216 OTR1XEZ3 Strong Altered Expression [1492]
ROPN1L OTRWZJ68 Strong Altered Expression [335]
RPGRIP1 OTABESO9 Strong Biomarker [1493]
RPGRIP1L OT6Z069I Strong Genetic Variation [1494]
RPL10 OTBHOZGC Strong Biomarker [1441]
RPL11 OT3VZ6OE Strong Biomarker [1495]
RPL29 OTUFIBJL Strong Biomarker [690]
RPTOR OT4TQZ9F Strong Genetic Variation [1496]
RRAS OTBBF28C Strong Genetic Variation [347]
RRS1 OTTNCZN6 Strong Biomarker [1497]
RSRC1 OTFCJ4S0 Strong Biomarker [1072]
RTL1 OTOT33IM Strong Biomarker [1498]
RTN3 OTGZ51QF Strong Biomarker [1499]
S100A7 OTJFVJRF Strong Biomarker [1500]
SAA2 OTYAVJWG Strong Biomarker [1501]
SCAPER OT7S3B3P Strong CausalMutation [1502]
SCGN OTGD7SKH Strong Biomarker [1503]
SDCCAG8 OTV2ZGV9 Strong Genetic Variation [1504]
SEC16A OTFNQ1ZU Strong Genetic Variation [634]
SELENBP1 OT3NZNTR Strong Genetic Variation [1145]
SELENOS OTUEWIU9 Strong Biomarker [1505]
SENP2 OTPQJXIR Strong Biomarker [1506]
SEPTIN11 OTX2O0ZX Strong Biomarker [1507]
SEPTIN9 OT1VMRFQ Strong Biomarker [822]
SERF1A OT9F7AMT Strong Biomarker [1508]
SERPINA4 OTBK0GG7 Strong Genetic Variation [1509]
SERPINA5 OTTZXPGD Strong Biomarker [1510]
SERPINB2 OT72QLZB Strong Biomarker [1511]
SESN2 OT889IXY Strong Altered Expression [405]
SETMAR OTE2MIMZ Strong Biomarker [1498]
SFPQ OTLCIAPJ Strong Altered Expression [1093]
SFRP1 OT0U9G41 Strong Altered Expression [1512]
SFRP2 OT8GZ0CA Strong Altered Expression [1513]
SFRP5 OTLCVVSH Strong Biomarker [1514]
SFXN1 OTL66767 Strong Biomarker [1515]
SGIP1 OTQW6R3Z Strong Biomarker [1516]
SGMS1 OTZQE7PW Strong Biomarker [1372]
SGMS2 OT3NHO99 Strong Biomarker [1517]
SGSM3 OTIB1P8A Strong Biomarker [1518]
SHC1 OT1J5IRN Strong Biomarker [1519]
SIGLEC12 OTC36XP9 Strong Biomarker [1520]
SIRT4 OT5S0J23 Strong Altered Expression [1521]
SIRT7 OT5M4OT4 Strong Biomarker [1522]
SLC35G1 OTKZUA8O Strong Altered Expression [1208]
SLN OTERIU75 Strong Biomarker [1523]
SMARCA2 OTSGJ8SV Strong Biomarker [1524]
SNAP29 OTT30ZON Strong Biomarker [1525]
SNED1 OTBQVXY5 Strong Biomarker [1526]
SNRNP70 OTP52YZ3 Strong Biomarker [1527]
SNRPN OTQB1ID1 Strong Genetic Variation [1528]
SOCS2 OTBPNKJQ Strong Biomarker [1529]
SOCS7 OT503VJG Strong Genetic Variation [1530]
SOD3 OTIOZQAB Strong Biomarker [1531]
SORBS3 OTVEUODC Strong Biomarker [1532]
SORCS1 OTP8PAKU Strong Biomarker [1533]
SORL1 OTQ8FFNS Strong Biomarker [1534]
SOX3 OT1CRCOB Strong Biomarker [875]
SOX6 OTT0W0LE Strong Biomarker [1535]
SPG7 OT8OY9ST Strong Biomarker [217]
SPI1 OTVCA1D0 Strong Biomarker [1536]
SPINK1 OTSUVAL2 Strong Biomarker [1537]
SPINK4 OTHTCW94 Strong Biomarker [1538]
SPTA1 OT1YMP65 Strong Biomarker [1539]
SPZ1 OTQH8HJ5 Strong Biomarker [1195]
SRSF1 OTF61HOV Strong Biomarker [1540]
ST13 OTNML6UP Strong Biomarker [690]
ST3GAL2 OT8WM21E Strong Biomarker [1541]
ST6GAL1 OT7US3NO Strong Genetic Variation [1277]
STAP2 OTEB1VVI Strong Genetic Variation [1542]
STEAP4 OTFTLAEZ Strong Altered Expression [1543]
STING1 OTDAP4G0 Strong Biomarker [1544]
STX16 OTM7TAOE Strong Genetic Variation [1545]
STX8 OTFOJCHI Strong Biomarker [1546]
STXBP3 OTTTYMAQ Strong Altered Expression [1547]
SUCLA2 OTMZD4PW Strong Biomarker [154]
SUCLG2 OT0KHLY2 Strong Biomarker [154]
SUGP1 OT7W0EB8 Strong Genetic Variation [798]
SUMO4 OT9B447E Strong Biomarker [1548]
SYT4 OTA1D7VL Strong Altered Expression [1549]
TAC3 OTOJGM38 Strong Biomarker [1550]
TADA2A OTXUMEL9 Strong Genetic Variation [1068]
TAL1 OTX4K6QZ Strong Biomarker [505]
TANK OTZSGFIK Strong Genetic Variation [1482]
TAS2R14 OTWA9CYC Strong Altered Expression [1551]
TAT OT2CJ91O Strong Biomarker [1552]
TBC1D4 OTK66C40 Strong Genetic Variation [1553]
TBCE OTGBSTKS Strong Genetic Variation [1554]
TBL1Y OTA0F7TM Strong Altered Expression [761]
TBPL1 OT4I143E Strong Biomarker [789]
TBX1 OTQLBPRA Strong Genetic Variation [818]
TBX15 OTAZ9QDX Strong Biomarker [1555]
TCEA1 OTBFO594 Strong Biomarker [1556]
TCERG1L OTSBSCLF Strong Biomarker [856]
TCF21 OT393IMA Strong Altered Expression [1557]
TCN2 OT41D0L3 Strong Genetic Variation [1558]
TERF2IP OT3M5P3G Strong Biomarker [1479]
TFAM OTXXV5V7 Strong Biomarker [818]
TFF2 OTRXB19X Strong Biomarker [1559]
THADA OTYZQX0F Strong Genetic Variation [1560]
THBS2 OTXET551 Strong Biomarker [1561]
THEM4 OTSIZU8Y Strong Biomarker [1562]
THEMIS OTXODBXJ Strong Genetic Variation [1563]
THRSP OTKYE01L Strong Biomarker [1564]
THSD7A OT7249HH Strong Biomarker [1565]
TIGAR OTR7NMRJ Strong Biomarker [1566]
TIMM44 OTXP7MXN Strong Biomarker [1278]
TIMP4 OT8A68SW Strong Altered Expression [1567]
TLR10 OTQ1KVJO Strong Altered Expression [1568]
TM7SF2 OTILU5S7 Strong Biomarker [318]
TMEM160 OTWVIV7I Strong Genetic Variation [1267]
TMEM26 OTHZCXYB Strong Altered Expression [1569]
TMTC1 OTZ7NW96 Strong Biomarker [1570]
TNFSF9 OTV9L89D Strong Biomarker [1571]
TNMD OTHLVA9G Strong Genetic Variation [1572]
TOB1 OTNW949D Strong Biomarker [999]
TOMM40 OTZDQ29F Strong Genetic Variation [374]
TRA2B OTZYQW52 Strong Altered Expression [1573]
TRIB1 OTPEO17G Strong Altered Expression [1551]
TRIM13 OTQIUACB Strong Biomarker [217]
TRIM32 OTJOV0PG Strong Biomarker [1574]
TRIM66 OT0VJCP6 Strong Genetic Variation [1072]
TRIM69 OTTEGTRD Strong Altered Expression [770]
TRPS1 OT7XPPEL Strong Genetic Variation [583]
TSC1 OTFF4YZ7 Strong Biomarker [1575]
TSC22D3 OT03UM03 Strong Altered Expression [1576]
TSPAN31 OT8WQ83R Strong Biomarker [1383]
TSPAN8 OT1F68WQ Strong Genetic Variation [1577]
TSPYL5 OT7QEI2X Strong Biomarker [1482]
TTC28 OTFOOYC3 Strong Genetic Variation [1330]
ALDOB OT7FR69A Definitive Biomarker [854]
CASZ1 OTWJ2OR8 Definitive Biomarker [829]
GAL3ST1 OTSFFZRD Definitive Biomarker [829]
MMRN1 OT7ZNYHT Definitive Biomarker [1578]
------------------------------------------------------------------------------------
⏷ Show the Full List of 978 DOT(s)

References

1 Pharmacotherapy for obesity. Drugs. 2005;65(10):1391-418.
2 Amphetamine FDA Label
3 Anastrozole FDA Label
4 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
5 Bupropion FDA Label
6 Fenofibrate FDA Label
7 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1133).
8 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2941).
9 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4797).
10 Methamphetamine FDA Label
11 Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
12 Metoprolol FDA Label
13 Naltrexone FDA Label
14 Drug information of Phenmetrazine, 2008. eduDrugs.
15 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7269).
16 Obesity: pathophysiology and clinical management. Curr Med Chem. 2009;16(4):506-21.
17 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5346).
18 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020
19 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2586).
20 Topiramate FDA Label
21 ClinicalTrials.gov (NCT01872182) Efficacy and Safety Study of ALS-L1023 in Patients With Abdominal Obesity of Metabolic Syndrome. U.S. National Institutes of Health.
22 DOV 216,303, a "triple" reuptake inhibitor: safety, tolerability, and pharmacokinetic profile. J Clin Pharmacol. 2004 Dec;44(12):1360-7.
23 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 610).
24 2011 Pipeline of Zafgen.
25 Cetilistat (ATL-962), a novel lipase inhibitor: a 12-week randomized, placebo-controlled study of weight reduction in obese patients. Int J Obes (Lond). 2007 Mar;31(3):494-9.
26 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4613).
27 Clinical pipeline report, company report or official report of Gmax Biopharm.
28 Clinical pipeline report, company report or official report of Gmax Biopharm.
29 ClinicalTrials.gov (NCT05869903) A Phase 3, Randomized, Double-Blind Study to Investigate the Efficacy and Safety of Once-Daily Oral LY3502970 Compared With Placebo in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-1). U.S.National Institutes of Health.
30 ClinicalTrials.gov (NCT05882045) A Randomized, Double-Blind, Phase 3 Study to Investigate the Efficacy and Safety of LY3437943 Once Weekly Compared to Placebo in Participants With Severe Obesity and Established Cardiovascular Disease. U.S.National Institutes of Health.
31 ClinicalTrials.gov (NCT02179151) Double-Blind, Placebo Controlled, Phase 3 Trial of ZGN-440 (Beloranib) in Obese Subjects With Prader-Willi Syndrome. U.S. National Institutes of Health.
32 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024671)
33 ClinicalTrials.gov (NCT05669599) A Phase 2 Randomized, Placebo-controlled, Double-blind, Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus. U.S.National Institutes of Health.
34 ClinicalTrials.gov (NCT05121441) A Phase 2, Placebo-Controlled, Randomized, Blinded Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of ARD-101 in Adults With Obesity. U.S.National Institutes of Health.
35 ClinicalTrials.gov (NCT00735683) A Short-Term Study to Examine the Effects of ATHX-105 Phosphate on Weight Loss and Safety. U.S. National Institutes of Health.
36 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3462).
37 ClinicalTrials.gov (NCT00367783) Safety, Toleration and Efficacy of CP-741,952 for the Treatment of Obesity. U.S. National Institutes of Health.
38 ClinicalTrials.gov (NCT01725126) To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes. U.S. National Institutes of Health.
39 Clinical pipeline report, company report or official report of Hemodynamic Therapeutics.
40 ClinicalTrials.gov (NCT02476019) A Safety, Tolerability, PK, and PD Study of Once Weekly ISIS-FGFR4RX SC in Obese Patients.
41 ClinicalTrials.gov (NCT03486392) A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Non-diabetic Severely Obese Participants. U.S. National Institutes of Health.
42 ClinicalTrials.gov (NCT00993421) A Weight Loss Study in Overweight Men and Women. U.S. National Institutes of Health.
43 ClinicalTrials.gov (NCT04881760) A Phase 2 Study of Once-Weekly LY3437943 Compared With Placebo in Participants Who Have Obesity or Are Overweight With Weight-Related Comorbidities. U.S.National Institutes of Health.
44 ClinicalTrials.gov (NCT02029586) Therapeutic Exploratory Phase 2 Study to Evaluate the Safety and Efficacy of MB12066 in Patients With Nonalcoholic Fatty Liver Disease(NAFLD) Except Cirrhosis. U.S. National Institutes of Health.
45 ClinicalTrials.gov (NCT05199090) A Randomized, Placebo-controlled, Participant-and-investigator- Blinded, Sponsor Open-label Study to Evaluate the Safety, Tolerability, and Efficacy With Different Dosing Regimens of Subcutaneously Administered MBL949 in Obese Participants With or Without Type 2 Diabetes Mellitus. U.S.National Institutes of Health.
46 ClinicalTrials.gov (NCT02317796) Adult Subjects With Uncontrolled Type 2 Diabetes. U.S. National Institutes of Health.
47 ClinicalTrials.gov (NCT00409305) The Effect of Betahistine on Body Weight in Obese Subjects. U.S. National Institutes of Health.
48 ClinicalTrials.gov (NCT00449202) Phase 2a Obesity Study of Oral Doses of Oleoyl-Estrone (MP-101). U.S. National Institutes of Health.
49 ClinicalTrials.gov (NCT00537420) A Study of Nasal PYY3-36 and Placebo for Weight Loss in Obese Subjects. U.S. National Institutes of Health.
50 ClinicalTrials.gov (NCT05579977) A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, DOSE RANGING, DOSE FINDING, PARALLEL GROUP STUDY TO ASSESS EFFICACY AND SAFETY OF PF-07081532, AND OPEN LABEL ORAL SEMAGLUTIDE, IN ADULTS WITH TYPE 2 DIABETES MELLITUS (T2DM) INADEQUATELY CONTROLLED ON METFORMIN, AND SEPARATELY PF-07081532 COMPARED TO MATCHING PLACEBO IN ADULTS WITH OBESITY BUT WITHOUT T2DM. U.S.National Institutes of Health.
51 2011 Pipeline of Proximagen Group plc.
52 ClinicalTrials.gov (NCT00239174) A Multicenter Study to Evaluate the Efficacy and Safety of of Four Doses of SR147778 in Obese Patients. U.S. National Institutes of Health.
53 Clinical pipeline report, company report or official report of TransTech Pharma (2011).
54 Clinical pipeline report, company report or official report of YSOPIA Bioscience
55 ClinicalTrials.gov (NCT02221765) Safety, Tolerability and Efficacy Study of PP1420 in HV. U.S. National Institutes of Health.
56 ClinicalTrials.gov (NCT05406115) A Phase 1, Randomized, Double-blind, Placebo Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 786 in Healthy Subjects and Subjects With Obesity. U.S.National Institutes of Health.
57 ClinicalTrials.gov (NCT02072993) A First Time in Man Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD1979 in Healthy Males. U.S. National Institutes of Health.
58 Clinical pipeline report, company report or official report of AstraZeneca (2011).
59 ClinicalTrials.gov (NCT05511025) A Phase I Randomized Single-blind Placebo-controlled Study to Assess the Safety, Tolerability, and Pharmacokinetics of AZD6234 Following Single Ascending Dose Administration to Healthy Subjects Who Are Overweight or Obese. U.S.National Institutes of Health.
60 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7827).
61 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7715).
62 2011 Pipeline of Bristol-Myers Squibb.
63 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023034)
64 Clinical pipeline report, company report or official report of CinFina Pharma
65 ClinicalTrials.gov (NCT04838405) A Phase 1 Randomized, Double Blind, Placebo Controlled, Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CT-388 in Otherwise Healthy Overweight and Obese Adult Participants and in Obese Patients With Type 2 Diabetes Mellitus. U.S.National Institutes of Health.
66 ClinicalTrials.gov (NCT04812262) A Phase 1, Randomized, Double-blind, Placebo-controlled, Single and Multiple Dose Study to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DD01 in Overweight/Obese Subjects With T2DM and NAFLD. U.S.National Institutes of Health.
67 ClinicalTrials.gov (NCT04890873) ERX1000 - A Phase I, Double-blind, Placebo-controlled, Single and Multiple Oral Dose, Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Male and Female Subjects With Obesity. U.S.National Institutes of Health.
68 ClinicalTrials.gov (NCT02235961) Investigate Safety, Tolerability and Pharmacokinetics for Single Doses of NNC9204-0530 Alone and in Combination With Liraglutide in Overweight to Obese But Otherwise Healthy Male Subjects. U.S. National Institutes of Health.
69 Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152). J Med Chem. 2012 May 10;55(9):4101-13.
70 Clinical pipeline report, company report or official report of GlaxoSmithKline (2011).
71 ClinicalTrials.gov (NCT01545570) A Study to Determine the Safety, Tolerability, and Effects of GSK2374697 in Healthy Volunteers. U.S. National Institutes of Health.
72 Kalypsys nearing completion of phase Ia study of KD3010 for metabolic disorders. Kalypsys. 2007.
73 Effect of a 28-d treatment with L-796568, a novel beta(3)-adrenergic receptor agonist, on energy expenditure and body composition in obese men. Am J Clin Nutr. 2002 Oct;76(4):780-8.
74 Clinical pipeline report, company report or official report of Novo Nordisk
75 ClinicalTrials.gov (NCT05380323) A Phase 1, Randomized, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety, Tolerability, and PK of LY3541105 Following Single Doses in Healthy/Overweight Participants and Multiple Doses in Overweight Participants. U.S.National Institutes of Health.
76 ClinicalTrials.gov (NCT05295940) A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3841136 in Healthy and Overweight Participants. U.S.National Institutes of Health.
77 ClinicalTrials.gov (NCT04838639) A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect of NO-13065 When Administered Orally to Healthy and Obese Adult Subjects. U.S.National Institutes of Health.
78 ClinicalTrials.gov (NCT05292911) A 12-Week Extension Study of ALT-801 in Diabetic and Non-Diabetic Overweight and Obese Subjects With Non-alcoholic Fatty Liver Disease (NAFLD). U.S.National Institutes of Health.
79 Prohibitin 1 (PHB; PHB1). SciBX 4(45); doi:10.1038/scibx.2011.1269. Nov. 17 2011
80 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021329)
81 Clinical pipeline report, company report or official report of Novo Nordisk
82 ClinicalTrials.gov (NCT05247970) A Phase 1 Randomized, Double-blind, Single and Multiple-dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Food Effect, and Drug-Drug Interactions of S-309309 in Healthy and Obese Adult Study Participants. U.S.National Institutes of Health.
83 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8705).
84 ClinicalTrials.gov (NCT00806338) An Ascending Multi-Dose, Tolerance and Pharmacokinetic Study in Obese or Overweight Type 2 Diabetic Volunteers. U.S. National Institutes of Health.
85 2011 Pipeline of Zealand Pharma.
86 2011 Pipeline of Zydus Cadila Group.
87 A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents. Expert Opin Ther Pat. 2015 Oct;25(10):1093-116.
88 Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58.
89 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 568).
90 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007390)
91 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1562).
92 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033560)
93 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031688)
94 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025707)
95 ClinicalTrials.gov (NCT00542009) A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight. U.S. National Institutes of Health.
96 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025197)
97 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013294)
98 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011891)
99 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015990)
100 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 890).
101 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1554).
102 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017654)
103 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023122)
104 New and emerging drug molecules against obesity. J Cardiovasc Pharmacol Ther. 2014 Jan;19(1):65-76.
105 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031455)
106 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019931)
107 Emerging drugs for eating disorder treatment. Expert Opin Emerg Drugs. 2006 May;11(2):315-36.
108 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024090)
109 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026874)
110 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006083)
111 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025311)
112 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029079)
113 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025588)
114 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025584)
115 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017316)
116 Clinical pipeline report, company report or official report of Shionogi (2011).
117 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 868).
118 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015967)
119 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012981)
120 Clinical pipeline report, company report or official report of University College London.
121 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 894).
122 2011 Pipeline of Jenrin Discovery.
123 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3467).
124 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1313).
125 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1314).
126 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001851)
127 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 858).
128 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021828)
129 Clinical pipeline report, company report or official report of Albany Molecular Research (2011).
130 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008694)
131 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000393)
132 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021433)
133 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003426)
134 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017024)
135 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006045)
136 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4023).
137 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
138 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 11).
139 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).
140 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).
141 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 56).
142 C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502.
143 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1265).
144 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 8).
145 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2490).
146 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8502).
147 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 246).
148 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2593).
149 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1540).
150 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1315).
151 A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II). Obesity (Silver Spring). 2013 May;21(5):935-43.
152 Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy. J Clin Pharm Ther. 2008 Oct;33(5):513-9.
153 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024638)
154 Orchestrated downregulation of genes involved in oxidative metabolic pathways in obese vs. lean high-fat young male consumers.J Physiol Biochem. 2011 Mar;67(1):15-26. doi: 10.1007/s13105-010-0044-4. Epub 2010 Sep 30.
155 ADAM17_i33708A>G polymorphism interacts with dietary n-6 polyunsaturated fatty acids to modulate obesity risk in the Genetics of Lipid Lowering Drugs and Diet Network study.Nutr Metab Cardiovasc Dis. 2010 Dec;20(10):698-705. doi: 10.1016/j.numecd.2009.06.011. Epub 2009 Oct 9.
156 Inducible Loss of the Aryl Hydrocarbon Receptor Activates Perigonadal White Fat Respiration and Brown Fat Thermogenesis via Fibroblast Growth Factor 21.Int J Mol Sci. 2019 Feb 22;20(4):950. doi: 10.3390/ijms20040950.
157 High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism.Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3138-3143. doi: 10.1073/pnas.1713837115. Epub 2018 Mar 5.
158 Obesity and synergistic risk factors for chronic kidney disease in African American adults: the Jackson Heart Study.Nephrol Dial Transplant. 2018 Jun 1;33(6):992-1001. doi: 10.1093/ndt/gfx230.
159 The BACE1 product sAPP induces ER stress and inflammation and impairs insulin signaling.Metabolism. 2018 Aug;85:59-75. doi: 10.1016/j.metabol.2018.03.005. Epub 2018 Mar 9.
160 Reduced biliverdin reductase-A levels are associated with early alterations of insulin signaling in obesity.Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1490-1501. doi: 10.1016/j.bbadis.2019.02.021. Epub 2019 Feb 28.
161 C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling.FASEB J. 2013 Feb;27(2):822-31. doi: 10.1096/fj.12-220582. Epub 2012 Nov 1.
162 Calcitonin gene-related peptide: neuroendocrine communication between the pancreas, gut, and brain in regulation of blood glucose.Ann Transl Med. 2017 Nov;5(21):419. doi: 10.21037/atm.2017.08.27.
163 Dual CCR2/5 Antagonist Attenuates Obesity-Induced Insulin Resistance by Regulating Macrophage Recruitment and M1/M2 Status.Obesity (Silver Spring). 2018 Feb;26(2):378-386. doi: 10.1002/oby.22103. Epub 2017 Dec 27.
164 Respiratory chain polymorphisms and obesity in the Spanish population, a cross-sectional study.BMJ Open. 2019 Feb 19;9(2):e027004. doi: 10.1136/bmjopen-2018-027004.
165 Independent modes of disease repair by AIM protein distinguished in AIM-felinized mice.Sci Rep. 2018 Sep 3;8(1):13157. doi: 10.1038/s41598-018-31580-6.
166 Genome-wide analysis reveals that altered methylation in specific CpG loci is associated with childhood obesity.J Cell Biochem. 2018 Sep;119(9):7490-7497. doi: 10.1002/jcb.27059. Epub 2018 May 24.
167 Prospective study of common variants in CX3CR1 and risk of macular degeneration: pooled analysis from 5 long-term studies.JAMA Ophthalmol. 2014 Jan;132(1):84-95. doi: 10.1001/jamaophthalmol.2013.5506.
168 Regulation of ammonia-metabolizing enzymes expression in the liver of obese rats: differences between genetic and nutritional obesities.Int J Obes Relat Metab Disord. 1997 Aug;21(8):681-5. doi: 10.1038/sj.ijo.0800460.
169 Obesity, visceral adiposity and carotid atherosclerosis.J Diabetes Complications. 2019 Apr;33(4):302-306. doi: 10.1016/j.jdiacomp.2019.01.002. Epub 2019 Jan 17.
170 [Effect of neonatal nutrition on the enzyme activity of liver lysosomes, adipocytes and thrombocytes in young and old rats].Vopr Pitan. 1986 Mar-Apr;(2):43-7.
171 Synergistic Modulation of Inflammatory but not Metabolic Effects of High-Fat Feeding by CCR2 and CX3CR1.Obesity (Silver Spring). 2017 Aug;25(8):1410-1420. doi: 10.1002/oby.21900. Epub 2017 Jun 26.
172 Maternal Diet-Induced Obesity Compromises Oxidative Stress Status and Angiogenesis in the Porcine Placenta by Upregulating Nox2 Expression.Oxid Med Cell Longev. 2019 Oct 1;2019:2481592. doi: 10.1155/2019/2481592. eCollection 2019.
173 Suboptimal bone microarchitecure in adolescent girls with obesity compared to normal-weight controls and girls with anorexia nervosa.Bone. 2019 May;122:246-253. doi: 10.1016/j.bone.2019.03.007. Epub 2019 Mar 7.
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558 Ablation of kallikrein 7 (KLK7) in adipose tissue ameliorates metabolic consequences of highfat diet-induced obesity by counteracting adipose tissue inflammation in vivo.Cell Mol Life Sci. 2018 Feb;75(4):727-742. doi: 10.1007/s00018-017-2658-y. Epub 2017 Sep 20.
559 Exposure to omentum adipose tissue conditioned medium from obese pregnant women promotes myometrial artery dysfunction.J Obstet Gynaecol Res. 2018 Jan;44(1):124-133. doi: 10.1111/jog.13482. Epub 2017 Oct 13.
560 Impact of Laparoscopic Sleeve Gastrectomy on Gut Permeability in Morbidly Obese Subjects.Obes Surg. 2019 Jul;29(7):2132-2143. doi: 10.1007/s11695-019-03815-6.
561 Increased cholesterol efflux capacity in metabolic syndrome: Relation with qualitative alterations in HDL and LCAT.Atherosclerosis. 2015 Sep;242(1):236-42. doi: 10.1016/j.atherosclerosis.2015.07.019. Epub 2015 Jul 10.
562 The lactase -13910C>T polymorphism (rs4988235) is associated with overweight/obesity and obesity-related variables in a population sample of Portuguese young adults.Eur J Clin Nutr. 2017 Jan;71(1):21-24. doi: 10.1038/ejcn.2016.164. Epub 2016 Aug 31.
563 GQ-11: A new PPAR agonist improves obesity-induced metabolic alterations in LDLr(-/-) mice.Int J Obes (Lond). 2018 Jun;42(5):1062-1072. doi: 10.1038/s41366-018-0011-7. Epub 2018 Jan 30.
564 Association of a gain-of-function variant in LGR4 with central obesity.Obesity (Silver Spring). 2017 Jan;25(1):252-260. doi: 10.1002/oby.21704. Epub 2016 Dec 7.
565 Ishige okamurae Extract Suppresses Obesity and Hepatic Steatosis in High Fat Diet-Induced Obese Mice.Nutrients. 2018 Nov 20;10(11):1802. doi: 10.3390/nu10111802.
566 Hypooxytocinaemia in obese Zucker rats relates to oxytocin degradation in liver and adipose tissue.J Endocrinol. 2014 Feb 10;220(3):333-43. doi: 10.1530/JOE-13-0417. Print 2014 Mar.
567 Placental Pim-1 expression is increased in obesity and regulates cytokine- and toll-like receptor-mediated inflammation.Placenta. 2017 May;53:101-112. doi: 10.1016/j.placenta.2017.04.010. Epub 2017 Apr 13.
568 Residual inflammatory risk in coronary heart disease: incidence of elevated high-sensitive CRP in a real-world cohort.Clin Res Cardiol. 2020 Mar;109(3):315-323. doi: 10.1007/s00392-019-01511-0. Epub 2019 Jul 19.
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570 Lysophosphatidic acid receptor mRNA levels in heart and white adipose tissue are associated with obesity in mice and humans.PLoS One. 2017 Dec 13;12(12):e0189402. doi: 10.1371/journal.pone.0189402. eCollection 2017.
571 Genetic identification of Ly75 as a novel quantitative trait gene for resistance to obesity in mice.Sci Rep. 2018 Dec 5;8(1):17658. doi: 10.1038/s41598-018-36073-0.
572 Blockade of myeloid differentiation protein 2 prevents obesity-induced inflammation and nephropathy.J Cell Mol Med. 2017 Dec;21(12):3776-3786. doi: 10.1111/jcmm.13287. Epub 2017 Aug 2.
573 Are dopaminergic genotypes risk factors for eating behavior and obesity in adults?.Neurosci Lett. 2017 Jul 27;654:28-32. doi: 10.1016/j.neulet.2017.06.023. Epub 2017 Jun 16.
574 Obesity is associated with genetic variants that alter dopamine availability.Ann Hum Genet. 2006 May;70(Pt 3):293-303. doi: 10.1111/j.1529-8817.2005.00228.x.
575 Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study.BMC Med Genet. 2016 Jan 22;17:7. doi: 10.1186/s12881-016-0268-4.
576 A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity.Cell Metab. 2014 Sep 2;20(3):499-511. doi: 10.1016/j.cmet.2014.06.008. Epub 2014 Jul 17.
577 Exercise ameliorates insulin resistance via regulating TGF-activated kinase 1 (TAK1)-mediated insulin signaling in liver of high-fat diet-induced obese rats.J Cell Physiol. 2019 May;234(5):7467-7474. doi: 10.1002/jcp.27508. Epub 2018 Oct 26.
578 MAP3K8 (TPL2/COT) affects obesity-induced adipose tissue inflammation without systemic effects in humans and in mice.PLoS One. 2014 Feb 24;9(2):e89615. doi: 10.1371/journal.pone.0089615. eCollection 2014.
579 Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity.Am J Physiol Endocrinol Metab. 2017 Sep 1;313(3):E303-E313. doi: 10.1152/ajpendo.00037.2017. Epub 2017 Jun 13.
580 JNK at the crossroad of obesity, insulin resistance, and cell stress response.Mol Metab. 2016 Dec 8;6(2):174-184. doi: 10.1016/j.molmet.2016.12.001. eCollection 2017 Feb.
581 JNK2 in myeloid cells impairs insulin's vasodilator effects in muscle during early obesity development through perivascular adipose tissue dysfunction.Am J Physiol Heart Circ Physiol. 2019 Aug 1;317(2):H364-H374. doi: 10.1152/ajpheart.00663.2018. Epub 2019 May 31.
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583 Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method.J Clin Endocrinol Metab. 2018 Jan 1;103(1):125-138. doi: 10.1210/jc.2017-01531.
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585 Ghrelin Reduces TNF--Induced Human Hepatocyte Apoptosis, Autophagy, and Pyroptosis: Role in Obesity-Associated NAFLD.J Clin Endocrinol Metab. 2019 Jan 1;104(1):21-37. doi: 10.1210/jc.2018-01171.
586 Association between urinary phthalates and metabolic abnormalities in obese Thai children and adolescents.J Pediatr Endocrinol Metab. 2017 Aug 28;30(9):931-938. doi: 10.1515/jpem-2017-0172.
587 A novel MC4R deletion coexisting with FTO and MC1R gene variants, causes severe early onset obesity.Hormones (Athens). 2016 Jul;15(3):445-452. doi: 10.14310/horm.2002.1686.
588 Whole genome microarray analysis of gene expression in Prader-Willi syndrome.Am J Med Genet A. 2007 Mar 1;143A(5):430-42. doi: 10.1002/ajmg.a.31606.
589 Exacerbation of autoimmune uveitis by obesity occurs through the melanocortin 5 receptor.J Leukoc Biol. 2019 Oct;106(4):879-887. doi: 10.1002/JLB.MA0119-030RR. Epub 2019 Jul 9.
590 SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [(18)F]FE@SNAP and [(11)C]SNAP-7941.Mol Imaging Biol. 2019 Apr;21(2):257-268. doi: 10.1007/s11307-018-1212-0.
591 Controlling Obesity and Metabolic Diseases by Hydrodynamic Delivery of a Fusion Gene of Exendin-4 and 1 Antitrypsin.Sci Rep. 2019 Sep 17;9(1):13427. doi: 10.1038/s41598-019-49757-y.
592 Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors.J Pharmacol Exp Ther. 2019 Nov;371(2):299-308. doi: 10.1124/jpet.119.259028. Epub 2019 Sep 19.
593 High-Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry (HPLC-ESI-MS(n)) Analysis and Bioactivity Useful for Prevention of "Diabesity" of Allium commutatum Guss.Plant Foods Hum Nutr. 2020 Mar;75(1):124-130. doi: 10.1007/s11130-019-00782-2.
594 Metabolic importance of adipose tissue monoacylglycerol acyltransferase 1 in mice and humans.J Lipid Res. 2018 Sep;59(9):1630-1639. doi: 10.1194/jlr.M084947. Epub 2018 May 31.
595 Monoacylglycerol lipase deficiency affects diet-induced obesity, fat absorption, and feeding behavior in CB(1) cannabinoid receptor-deficient mice.FASEB J. 2019 Feb;33(2):2484-2497. doi: 10.1096/fj.201801203R. Epub 2018 Sep 28.
596 Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation.Nat Commun. 2018 Aug 24;9(1):3404. doi: 10.1038/s41467-018-05721-4.
597 Expression of genes regulating malonyl-CoA in human skeletal muscle.J Cell Biochem. 2006 Oct 15;99(3):860-7. doi: 10.1002/jcb.20944.
598 Derangements in adrenergic-adipokine signalling establish a neurohormonal basis for obesity-related heart failure with a preserved ejection fraction.Eur J Heart Fail. 2018 May;20(5):873-878. doi: 10.1002/ejhf.1167. Epub 2018 Mar 1.
599 Obesity-associated dysregulation of calpastatin and MMP-15 in adipose-derived stromal cells results in their enhanced invasion.Stem Cells. 2012 Dec;30(12):2774-83. doi: 10.1002/stem.1229.
600 Pharmacological myeloperoxidase (MPO) inhibition in an obese/hypertensive mouse model attenuates obesity and liver damage, but not cardiac remodeling.Sci Rep. 2019 Dec 10;9(1):18765. doi: 10.1038/s41598-019-55263-y.
601 The Ron Receptor Tyrosine Kinase Regulates Macrophage Heterogeneity and Plays a Protective Role in Diet-Induced Obesity, Atherosclerosis, and Hepatosteatosis.J Immunol. 2016 Jul 1;197(1):256-65. doi: 10.4049/jimmunol.1600450. Epub 2016 May 27.
602 Syzygium cumini Leaf Extract Reverts Hypertriglyceridemia via Downregulation of the Hepatic XBP-1s/PDI/MTP Axis in Monosodium L-Glutamate-Induced Obese Rats.Oxid Med Cell Longev. 2019 Mar 21;2019:9417498. doi: 10.1155/2019/9417498. eCollection 2019.
603 The combined effects of FADS gene variation and dietary fats in obesity-related traits in a population from the far north of Sweden: the GLACIER Study.Int J Obes (Lond). 2019 Apr;43(4):808-820. doi: 10.1038/s41366-018-0112-3. Epub 2018 May 24.
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606 Hookah smoking is strongly associated with diabetes mellitus, metabolic syndrome and obesity: a population-based study.Diabetol Metab Syndr. 2018 Apr 19;10:33. doi: 10.1186/s13098-018-0335-4. eCollection 2018.
607 Plasma concentration and expression of adipokines in epicardial and subcutaneous adipose tissue are associated with impaired left ventricular filling pattern.J Transl Med. 2019 Sep 18;17(1):310. doi: 10.1186/s12967-019-2060-7.
608 Oxidative Stress in Response to Saturated Fat Ingestion Is Linked to Insulin Resistance and Hyperandrogenism in Polycystic Ovary Syndrome.J Clin Endocrinol Metab. 2019 Nov 1;104(11):5360-5371. doi: 10.1210/jc.2019-00987.
609 Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice.Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E423-34. doi: 10.1152/ajpendo.00088.2010. Epub 2010 Jun 29.
610 Overweight condition and waist circumference and a candidate gene within the 12q24 locus.Cardiovasc Diabetol. 2013 Jan 3;12:2. doi: 10.1186/1475-2840-12-2.
611 Development of insulin resistance in Nischarin mutant female mice.Int J Obes (Lond). 2019 May;43(5):1046-1057. doi: 10.1038/s41366-018-0241-8. Epub 2018 Dec 13.
612 Compound C attenuates NLRP3 inflammasome despite AMPK knockdown in LPS plus palmitate-induced THP-1 cells.Naunyn Schmiedebergs Arch Pharmacol. 2020 Jan;393(1):67-76. doi: 10.1007/s00210-019-01712-4. Epub 2019 Aug 16.
613 Transnasal Delivery of the Peptide Agonist Specific to Neuromedin-U Receptor 2 to the Brain for the Treatment of Obesity.Mol Pharm. 2020 Jan 6;17(1):32-39. doi: 10.1021/acs.molpharmaceut.9b00571. Epub 2019 Dec 9.
614 Saturated Fatty Acid Activates T Cell Inflammation Through a Nicotinamide Nucleotide Transhydrogenase (NNT)-Dependent Mechanism.Biomolecules. 2019 Feb 25;9(2):79. doi: 10.3390/biom9020079.
615 iNOS as a metabolic enzyme under stress conditions.Free Radic Biol Med. 2020 Jan;146:16-35. doi: 10.1016/j.freeradbiomed.2019.10.411. Epub 2019 Oct 28.
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617 Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.Annu Rev Physiol. 2011;73:239-59. doi: 10.1146/annurev-physiol-012110-142233.
618 Association between serum prostate-specific antigen level and diabetes, obesity, hypertension, and the laboratory parameters related to glucose tolerance, hepatic function, and lipid profile: implications for modification of prostate-specific antigen threshold.Int J Clin Oncol. 2020 Mar;25(3):472-478. doi: 10.1007/s10147-019-01527-6. Epub 2019 Aug 22.
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620 Differential protein profiling as a potential multi-marker approach for obese patients with heart failure: A retrospective study.Sci Rep. 2018 May 21;8(1):7894. doi: 10.1038/s41598-018-26118-9.
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625 The expression of NAD(P)H:quinone oxidoreductase 1 is high in human adipose tissue, reduced by weight loss, and correlates with adiposity, insulin sensitivity, and markers of liver dysfunction.J Clin Endocrinol Metab. 2007 Jun;92(6):2346-52. doi: 10.1210/jc.2006-2476. Epub 2007 Apr 3.
626 Intake of an Obesogenic Cafeteria Diet Affects Body Weight, Feeding Behavior, and Glucose and Lipid Metabolism in a Photoperiod-Dependent Manner in F344 Rats.Front Physiol. 2018 Nov 26;9:1639. doi: 10.3389/fphys.2018.01639. eCollection 2018.
627 Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney.Am J Physiol Renal Physiol. 2018 Apr 1;314(4):F551-F560. doi: 10.1152/ajprenal.00390.2017. Epub 2017 Dec 6.
628 Carbohydrate restriction in the morning increases weight loss effect of a hypocaloric Mediterranean type diet: a randomized, parallel group dietary intervention in overweight and obese subjects.Nutrition. 2020 Mar;71:110578. doi: 10.1016/j.nut.2019.110578. Epub 2019 Sep 5.
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630 NURR1 activation in skeletal muscle controls systemic energy homeostasis.Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11299-11308. doi: 10.1073/pnas.1902490116. Epub 2019 May 20.
631 A systematic review of the association of neuregulin 4, a brown fat-enriched secreted factor, with obesity and related metabolic disturbances.Obes Rev. 2020 Feb;21(2):e12952. doi: 10.1111/obr.12952. Epub 2019 Nov 28.
632 Neurotensin Receptor-1 Identifies a Subset of Ventral Tegmental Dopamine Neurons that Coordinates Energy Balance.Cell Rep. 2017 Aug 22;20(8):1881-1892. doi: 10.1016/j.celrep.2017.08.001.
633 OGG1 Ser326Cys polymorphism, HIV, obesity and air pollution exposure influences adverse birth outcome susceptibility, within South African Women.Reprod Toxicol. 2018 Aug;79:8-15. doi: 10.1016/j.reprotox.2018.04.012. Epub 2018 Apr 27.
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636 -opioid receptor system mediates reward processing in humans.Nat Commun. 2018 Apr 16;9(1):1500. doi: 10.1038/s41467-018-03848-y.
637 A Role for Oncostatin M in the Impairment of Glucose Homeostasis in Obesity.J Clin Endocrinol Metab. 2020 Mar 1;105(3):e337-48. doi: 10.1210/clinem/dgz090.
638 Oxytocin in metabolic homeostasis: implications for obesity and diabetes management.Obes Rev. 2019 Jan;20(1):22-40. doi: 10.1111/obr.12757. Epub 2018 Sep 25.
639 Predictors of Groin Access Pseudoaneurysm Complication: A 10-Year Institutional Experience.Vasc Endovascular Surg. 2020 Jan;54(1):42-46. doi: 10.1177/1538574419879568. Epub 2019 Oct 2.
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642 A Positive Allosteric Modulator of the Serotonin 5-HT(2C) Receptor for Obesity.J Med Chem. 2017 Dec 14;60(23):9575-9584. doi: 10.1021/acs.jmedchem.7b00994. Epub 2017 Nov 17.
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644 PARP-2 regulates SIRT1 expression and whole-body energy expenditure.Cell Metab. 2011 Apr 6;13(4):450-460. doi: 10.1016/j.cmet.2011.03.013.
645 PAS kinase drives lipogenesis through SREBP-1 maturation.Cell Rep. 2014 Jul 10;8(1):242-55. doi: 10.1016/j.celrep.2014.06.006. Epub 2014 Jul 4.
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647 Lipidomics reveals a link between CYP1B1 and SCD1 in promoting obesity.J Proteome Res. 2014 May 2;13(5):2679-87. doi: 10.1021/pr500145n. Epub 2014 Apr 10.
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652 GPR120 protects lipotoxicity-induced pancreatic -cell dysfunction through regulation of PDX1 expression and inhibition of islet inflammation.Clin Sci (Lond). 2019 Jan 11;133(1):101-116. doi: 10.1042/CS20180836. Print 2019 Jan 15.
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654 Gene-by-environment interactions of the CLOCK, PEMT, and GHRELINloci with average sleep duration in relation to obesity traitsusing a cohort of 643 New Zealand European children.Sleep Med. 2017 Sep;37:19-26. doi: 10.1016/j.sleep.2017.05.017. Epub 2017 Jun 24.
655 Small molecule PGC-11 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration.Mol Metab. 2018 Mar;9:28-42. doi: 10.1016/j.molmet.2018.01.017. Epub 2018 Feb 3.
656 Progesterone receptor status modifies the association between body mass index and prognosis in women diagnosed with estrogen receptor positive breast cancer.Int J Cancer. 2020 May 15;146(10):2736-2745. doi: 10.1002/ijc.32621. Epub 2019 Aug 23.
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658 Enhanced -adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110 inactivation in adipose tissue.Nat Commun. 2019 Apr 4;10(1):1546. doi: 10.1038/s41467-019-09514-1.
659 Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.Cell Rep. 2019 Mar 19;26(12):3221-3230.e3. doi: 10.1016/j.celrep.2019.02.066.
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661 A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes.Hum Mol Genet. 2018 Sep 1;27(17):3099-3112. doi: 10.1093/hmg/ddy217.
662 Differential expression of Lp-PLA2 in obesity and type 2 diabetes and the influence of lipids.Diabetologia. 2018 May;61(5):1155-1166. doi: 10.1007/s00125-018-4558-6. Epub 2018 Feb 9.
663 Genome-Wide Association Studies of the Human Gut Microbiota.PLoS One. 2015 Nov 3;10(11):e0140301. doi: 10.1371/journal.pone.0140301. eCollection 2015.
664 A Noncanonical Role for Plasminogen Activator Inhibitor Type 1 in Obesity-Induced Diabetes.Am J Pathol. 2019 Jul;189(7):1413-1422. doi: 10.1016/j.ajpath.2019.04.004. Epub 2019 May 2.
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666 Laparoscopic hysterectomy in the overweight and obese: does 3D imaging make a change?.Arch Gynecol Obstet. 2017 Jan;295(1):125-131. doi: 10.1007/s00404-016-4215-6. Epub 2016 Oct 13.
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668 Phillyrin lowers body weight in obese mice via the modulation of PPAR<beta>/<delta>-ANGPTL 4 pathway.Obes Res Clin Pract. 2018 Jan-Feb;12(Suppl 2):71-79. doi: 10.1016/j.orcp.2017.02.002. Epub 2017 Mar 17.
669 Elevated Serum Cyclophilin B Levels Are Associated with the Prevalence and Severity of Metabolic Syndrome.Front Endocrinol (Lausanne). 2017 Dec 22;8:360. doi: 10.3389/fendo.2017.00360. eCollection 2017.
670 Mitochondrial Hyperacetylation in the Failing Hearts of Obese Patients Mediated Partly by a Reduction in SIRT3: The Involvement of the Mitochondrial Permeability Transition Pore.Cell Physiol Biochem. 2019;53(3):465-479. doi: 10.33594/000000151.
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679 Obesity alters phosphoramide mustard-induced ovarian DNA repair in mice.Biol Reprod. 2017 Feb 1;96(2):491-501. doi: 10.1095/biolreprod.116.143800.
680 Human Protein Kinases and Obesity.Adv Exp Med Biol. 2017;960:111-134. doi: 10.1007/978-3-319-48382-5_5.
681 Suppression of Prolactin Secretion Partially Explains the Antidiabetic Effect of Bromocriptine in ob/ob Mice.Endocrinology. 2019 Jan 1;160(1):193-204. doi: 10.1210/en.2018-00629.
682 Association of acrylamide hemoglobin biomarkers with obesity, abdominal obesity and overweight in general US population: NHANES 2003-2006.Sci Total Environ. 2018 Aug 1;631-632:589-596. doi: 10.1016/j.scitotenv.2018.02.338. Epub 2018 Mar 16.
683 Prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism and parameters of the metabolic syndrome.Mol Nutr Food Res. 2007 Dec;51(12):1447-51. doi: 10.1002/mnfr.200700144.
684 The Dualistic Effect of COX-2-Mediated Signaling in Obesity and Insulin Resistance.Int J Mol Sci. 2019 Jun 26;20(13):3115. doi: 10.3390/ijms20133115.
685 Children and adolescents with obesity have reduced serum bone turnover markers and 25-hydroxyvitamin D but increased parathyroid hormone concentrations - Results derived from new pediatric reference ranges.Bone. 2020 Mar;132:115124. doi: 10.1016/j.bone.2019.115124. Epub 2019 Dec 9.
686 Insulin regulates POMC neuronal plasticity to control glucose metabolism.Elife. 2018 Sep 19;7:e38704. doi: 10.7554/eLife.38704.
687 PTPRJ Inhibits Leptin Signaling, and Induction of PTPRJ in the Hypothalamus Is a Cause of the Development of Leptin Resistance.Sci Rep. 2017 Sep 14;7(1):11627. doi: 10.1038/s41598-017-12070-7.
688 PTPRS and PER3 methylation levels are associated with childhood obesity: results from a genome-wide methylation analysis.Pediatr Obes. 2018 Mar;13(3):149-158. doi: 10.1111/ijpo.12224. Epub 2017 Jun 14.
689 Epac2a-null mice exhibit obesity-prone nature more susceptible to leptin resistance.Int J Obes (Lond). 2017 Feb;41(2):279-288. doi: 10.1038/ijo.2016.208. Epub 2016 Nov 21.
690 PAP/HIP protein is an obesogenic factor.J Cell Physiol. 2014 Feb;229(2):225-31. doi: 10.1002/jcp.24438.
691 Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals.Clin Epigenetics. 2017 Feb 14;9:20. doi: 10.1186/s13148-016-0301-7. eCollection 2017.
692 15q26.1 microdeletion encompassing only CHD2 and RGMA in two adults with moderate intellectual disability, epilepsy and truncal obesity.Eur J Med Genet. 2014 Sep;57(9):520-3. doi: 10.1016/j.ejmg.2014.06.003. Epub 2014 Jun 13.
693 An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women.BMC Genet. 2016 Aug 24;17(1):121. doi: 10.1186/s12863-016-0428-8.
694 Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity.Mol Psychiatry. 2020 Sep;25(9):2058-2069. doi: 10.1038/s41380-018-0120-7. Epub 2018 Jun 28.
695 On the replication of genetic associations: timing can be everything!.Am J Hum Genet. 2008 Apr;82(4):849-58. doi: 10.1016/j.ajhg.2008.01.018.
696 Emotional eating and in vivo norepinephrine transporter availability in obesity: A [(11) C]MRB PET pilot study.Int J Eat Disord. 2017 Feb;50(2):152-156. doi: 10.1002/eat.22621. Epub 2016 Sep 9.
697 Ferulic Acid Produced by Lactobacillus fermentum Influences Developmental Growth Through a dTOR-Mediated Mechanism.Mol Biotechnol. 2019 Jan;61(1):1-11. doi: 10.1007/s12033-018-0119-y.
698 Somatic expression of ENRAGE is associated with obesity status among patients with clear cell renal cell carcinoma.Carcinogenesis. 2014 Apr;35(4):822-7. doi: 10.1093/carcin/bgt485. Epub 2013 Dec 28.
699 Proximal radial artery arteriovenous fistula for hemodialysis vascular access.J Vasc Surg. 2018 Jan;67(1):244-253. doi: 10.1016/j.jvs.2017.06.114. Epub 2017 Sep 11.
700 S100A8/A9 (Calprotectin), Interleukin-6, and C-Reactive Protein in Obesity and Diabetes before and after Roux-en-Y Gastric Bypass Surgery.Obes Facts. 2017;10(4):386-395. doi: 10.1159/000478097. Epub 2017 Aug 23.
701 Increased plasma sphingosine-1-phosphate in obese individuals and its capacity to increase the expression of plasminogen activator inhibitor-1 in adipocytes.Coron Artery Dis. 2013 Dec;24(8):642-50. doi: 10.1097/MCA.0000000000000033.
702 Silencing of SAA1 inhibits palmitate- or high-fat diet induced insulin resistance through suppression of the NF-B pathway.Mol Med. 2019 May 6;25(1):17. doi: 10.1186/s10020-019-0075-4.
703 Obese women exhibit differences in ovarian metabolites, hormones, and gene expression compared with moderate-weight women.J Clin Endocrinol Metab. 2009 May;94(5):1533-40. doi: 10.1210/jc.2008-2648. Epub 2009 Feb 17.
704 Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver.Biochem Biophys Res Commun. 2019 Jan 1;508(1):87-91. doi: 10.1016/j.bbrc.2018.11.083. Epub 2018 Nov 22.
705 Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population.J Hum Genet. 2011 Sep;56(9):647-51. doi: 10.1038/jhg.2011.74. Epub 2011 Jul 28.
706 Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3.Cell. 2001 Jul 13;106(1):105-16. doi: 10.1016/s0092-8674(01)00415-9.
707 Increased levels of platelet activation markers are positively associated with carotid wall thickness and other atherosclerotic risk factors in obese patients.Thromb Haemost. 2011 Oct;106(4):683-92. doi: 10.1160/TH11-01-0030. Epub 2011 Aug 25.
708 Co-Expression Networks Reveal Potential Regulatory Roles of miRNAs in Fatty Acid Composition of Nelore Cattle.Front Genet. 2019 Jul 11;10:651. doi: 10.3389/fgene.2019.00651. eCollection 2019.
709 Genome-wide analysis identifies an african-specific variant in SEMA4D associated with body mass index.Obesity (Silver Spring). 2017 Apr;25(4):794-800. doi: 10.1002/oby.21804. Epub 2017 Mar 13.
710 Genomic determinants of long-term cardiometabolic complications in childhood acute lymphoblastic leukemia survivors.BMC Cancer. 2017 Nov 10;17(1):751. doi: 10.1186/s12885-017-3722-6.
711 Effect of long-term sodium nitrate administration on diabetes-induced anemia and glucose homeostasis in obese type 2 diabetic male rats.Nitric Oxide. 2019 May 1;86:21-30. doi: 10.1016/j.niox.2019.02.003. Epub 2019 Feb 14.
712 Serum Surfactant Protein D as a Biomarker for Measuring Lung Involvement in Obese Patients With Type 2 Diabetes.J Clin Endocrinol Metab. 2017 Nov 1;102(11):4109-4116. doi: 10.1210/jc.2017-00913.
713 Sexual Dimorphism in Obesity-Associated Endothelial ENaC Activity and Stiffening in Mice.Endocrinology. 2019 Dec 1;160(12):2918-2928. doi: 10.1210/en.2019-00483.
714 Endophilin A2: A Potential Link to Adiposity and Beyond.Mol Cells. 2017 Nov 30;40(11):855-863. doi: 10.14348/molcells.2017.0137. Epub 2017 Nov 6.
715 Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice.J Clin Invest. 2010 Dec;120(12):4316-31. doi: 10.1172/JCI41624. Epub 2010 Nov 15.
716 Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.Nat Commun. 2014 Jun 2;5:3983. doi: 10.1038/ncomms4983.
717 Reduced SIRT1 and SIRT2 expression promotes adipogenesis of human visceral adipose stem cells and associates with accumulation of visceral fat in human obesity.Int J Obes (Lond). 2020 Feb;44(2):307-319. doi: 10.1038/s41366-019-0436-7. Epub 2019 Aug 28.
718 Glutathione as a mediator of cartilage oxidative stress resistance and resilience during aging and osteoarthritis.Connect Tissue Res. 2020 Jan;61(1):34-47. doi: 10.1080/03008207.2019.1665035. Epub 2019 Sep 15.
719 SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.EBioMedicine. 2018 Oct;36:347-357. doi: 10.1016/j.ebiom.2018.09.037. Epub 2018 Sep 29.
720 Gender-based differences on the association between salt-sensitive genes and obesity in Korean children aged between 8 and 9 years.PLoS One. 2015 Mar 13;10(3):e0120111. doi: 10.1371/journal.pone.0120111. eCollection 2015.
721 Physiological and therapeutic regulation of glucose homeostasis by upper small intestinal PepT1-mediated protein sensing.Nat Commun. 2018 Mar 16;9(1):1118. doi: 10.1038/s41467-018-03490-8.
722 Potential epigenetic biomarkers of obesity-related insulin resistance in human whole-blood.Epigenetics. 2017 Apr 3;12(4):254-263. doi: 10.1080/15592294.2017.1281501. Epub 2017 Jan 20.
723 Effects of SLC22A1 Polymorphisms on Metformin-Induced Reductions in Adiposity and Metformin Pharmacokinetics in Obese Children With Insulin Resistance.J Clin Pharmacol. 2017 Feb;57(2):219-229. doi: 10.1002/jcph.796. Epub 2016 Aug 23.
724 Urate transporter gene SLC22A12 polymorphisms associated with obesity and metabolic syndrome in Caucasians with hypertension.Kidney Blood Press Res. 2012;35(6):477-82. doi: 10.1159/000337370. Epub 2012 Jun 8.
725 Organic Cation Transporter 2 Overexpression May Confer an Increased Risk of Gentamicin-Induced Nephrotoxicity. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5573-80. doi: 10.1128/AAC.00907-16. Print 2016 Sep.
726 Expression of fatty-acid-handling proteins in human adipose tissue in relation to obesity and insulin resistance.Diabetologia. 2004 Jun;47(6):1118-25. doi: 10.1007/s00125-004-1417-4. Epub 2004 May 28.
727 Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.Diabetes. 2019 Jun;68(6):1197-1209. doi: 10.2337/db18-1321. Epub 2019 Apr 1.
728 AT1-receptor blockade attenuates outward aortic remodeling associated with diet-induced obesity in mice.Clin Sci (Lond). 2017 Jul 13;131(15):1989-2005. doi: 10.1042/CS20170131. Print 2017 Aug 1.
729 Liver-directed gene therapy for murine glycogen storage disease type Ib.Hum Mol Genet. 2017 Nov 15;26(22):4395-4405. doi: 10.1093/hmg/ddx325.
730 Hypoxic Stress Upregulates the Expression of Slc38a1 in Brown Adipocytes via Hypoxia-Inducible Factor-1.Pharmacology. 2018;101(1-2):64-71. doi: 10.1159/000480405. Epub 2017 Oct 25.
731 Inhibition of SNAT5 Induces Incretin-Responsive State From Incretin-Unresponsive State in Pancreatic -Cells: Study of -Cell Spheroid Clusters as a Model.Diabetes. 2018 Sep;67(9):1795-1806. doi: 10.2337/db17-1486. Epub 2018 Jun 28.
732 The effects of licogliflozin, a dual SGLT1/2 inhibitor, on body weight in obese patients with or without diabetes.Diabetes Obes Metab. 2019 Jun;21(6):1311-1321. doi: 10.1111/dom.13654. Epub 2019 Mar 15.
733 Emerging Role of SGLT-2 Inhibitors for the Treatment of Obesity.Drugs. 2019 Feb;79(3):219-230. doi: 10.1007/s40265-019-1057-0.
734 Transgenic mice overexpressing gamma-aminobutyric acid transporter subtype I develop obesity.Cell Res. 2000 Dec;10(4):303-10. doi: 10.1038/sj.cr.7290057.
735 Missense mutation in SLIT2 associated with congenital myopia, anisometropia, connective tissue abnormalities, and obesity.Orphanet J Rare Dis. 2018 Aug 15;13(1):138. doi: 10.1186/s13023-018-0885-4.
736 The aberrant expression of Smad6 and TGF- in obesity linked cardiac disease.Eur Rev Med Pharmacol Sci. 2017 Jan;21(1):138-142.
737 SNAP-25 Puts SNAREs at Center Stage in Metabolic Disease.Neuroscience. 2019 Nov 10;420:86-96. doi: 10.1016/j.neuroscience.2018.07.035. Epub 2018 Jul 31.
738 Gamma-synuclein is an adipocyte-neuron gene coordinately expressed with leptin and increased in human obesity.J Nutr. 2008 May;138(5):841-8. doi: 10.1093/jn/138.5.841.
739 The Association between SOCS1-1656G>A Polymorphism, Insulin Resistance and Obesity in Nonalcoholic Fatty Liver Disease (NAFLD) Patients.J Clin Med. 2019 Nov 8;8(11):1912. doi: 10.3390/jcm8111912.
740 The correlation between oxidative stress level and intra-abdominal fat in obese males.Medicine (Baltimore). 2019 Feb;98(7):e14469. doi: 10.1097/MD.0000000000014469.
741 Regulatory Roles of Sortilin and SorLA in Immune-Related Processes.Front Pharmacol. 2019 Jan 7;9:1507. doi: 10.3389/fphar.2018.01507. eCollection 2018.
742 Promise(s) of mesenchymal stem cells as an in vitro model system to depict pre-diabetic/diabetic milieu in WNIN/GR-Ob mutant rats.PLoS One. 2012;7(10):e48061. doi: 10.1371/journal.pone.0048061. Epub 2012 Oct 29.
743 SPARC is required for the maintenance of glucose homeostasis and insulin secretion in mice.Clin Sci (Lond). 2019 Jan 30;133(2):351-365. doi: 10.1042/CS20180714. Print 2019 Jan 31.
744 Promoting Self-Regulation in Health Among Vulnerable Brazilian Children: Protocol Study.Front Psychol. 2018 May 7;9:651. doi: 10.3389/fpsyg.2018.00651. eCollection 2018.
745 Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance.Am J Physiol Endocrinol Metab. 2014 Apr 1;306(7):E756-68. doi: 10.1152/ajpendo.00549.2013. Epub 2014 Jan 28.
746 Association between the SPRY1 gene polymorphism and obesity-related traits and osteoporosis in Korean women.Mol Genet Metab. 2013 Jan;108(1):95-101. doi: 10.1016/j.ymgme.2012.10.017. Epub 2012 Oct 24.
747 Utility of the ELF Test for Detecting Steatohepatitis in Morbid Obese Patients with Suspicion of Nonalcoholic Fatty Liver Disease.Obes Surg. 2017 Sep;27(9):2347-2353. doi: 10.1007/s11695-017-2606-9.
748 Metabolic endotoxemia promotes adipose dysfunction and inflammation in human obesity.Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E319-E332. doi: 10.1152/ajpendo.00277.2018. Epub 2018 Nov 13.
749 The gene-gene interaction of INSIG-SCAP-SREBP pathway on the risk of obesity in Chinese children.Biomed Res Int. 2014;2014:538564. doi: 10.1155/2014/538564. Epub 2014 Jun 17.
750 The rs1466113 polymorphism in the somatostatin receptor 2 gene is associated with obesity and food intake in a Mediterranean population.Ann Nutr Metab. 2010;57(2):124-31. doi: 10.1159/000319453. Epub 2010 Oct 19.
751 Indole Derivatives Isolated from Brown Alga Sargassum thunbergii Inhibit Adipogenesis through AMPK Activation in 3T3-L1 Preadipocytes.Mar Drugs. 2017 Apr 12;15(4):119. doi: 10.3390/md15040119.
752 The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children.PLoS One. 2013 Aug 15;8(8):e71353. doi: 10.1371/journal.pone.0071353. eCollection 2013.
753 Inactivation of SPAK kinase reduces body weight gain in mice fed a high-fat diet by improving energy expenditure and insulin sensitivity.Am J Physiol Endocrinol Metab. 2018 Jan 1;314(1):E53-E65. doi: 10.1152/ajpendo.00108.2017. Epub 2017 Oct 24.
754 Human omental adipose-derived stem cells from donors with different body mass index had similar effects on proliferation and migration of endometrial cancer cells in vitro.J Obstet Gynaecol Res. 2019 Feb;45(2):417-427. doi: 10.1111/jog.13820. Epub 2018 Oct 1.
755 SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity.Nat Immunol. 2019 May;20(5):581-592. doi: 10.1038/s41590-019-0372-7. Epub 2019 Apr 8.
756 SULF2 strongly prediposes to fasting and postprandial triglycerides in patients with obesity and type 2 diabetes mellitus.Obesity (Silver Spring). 2014 May;22(5):1309-16. doi: 10.1002/oby.20682. Epub 2014 Jan 9.
757 ALDH2 protects against high fat diet-induced obesity cardiomyopathy and defective autophagy: role of CaM kinase II, histone H3K9 methyltransferase SUV39H, Sirt1, and PGC-1 deacetylation.Int J Obes (Lond). 2018 Jun;42(5):1073-1087. doi: 10.1038/s41366-018-0030-4. Epub 2018 Mar 13.
758 ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes.Nat Commun. 2018 Sep 10;9(1):3659. doi: 10.1038/s41467-018-06091-7.
759 Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists.Eur J Med Chem. 2018 Feb 25;146:171-184. doi: 10.1016/j.ejmech.2018.01.059. Epub 2018 Feb 4.
760 Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKK for the treatment of obesity.Bioorg Med Chem. 2018 Nov 1;26(20):5443-5461. doi: 10.1016/j.bmc.2018.09.020. Epub 2018 Sep 20.
761 Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.Cell Metab. 2011 Apr 6;13(4):389-400. doi: 10.1016/j.cmet.2011.02.011.
762 Polymorphisms and high on-aspirin platelet reactivity after off-pump coronary artery bypass grafting.Scand Cardiovasc J. 2013 Aug;47(4):194-9. doi: 10.3109/14017431.2013.800640. Epub 2013 May 31.
763 Overexpression of C-type Natriuretic Peptide in Endothelial Cells Protects against Insulin Resistance and Inflammation during Diet-induced Obesity.Sci Rep. 2017 Aug 29;7(1):9807. doi: 10.1038/s41598-017-10240-1.
764 Obesity Is Associated with Changes in Iron Nutrition Status and Its Homeostatic Regulation in Pregnancy.Nutrients. 2019 Mar 23;11(3):693. doi: 10.3390/nu11030693.
765 The transcription factor paired-related homeobox 1 (Prrx1) inhibits adipogenesis by activating transforming growth factor- (TGF) signaling.J Biol Chem. 2013 Feb 1;288(5):3036-47. doi: 10.1074/jbc.M112.440370. Epub 2012 Dec 17.
766 Thrombomodulin, alarmin signaling, and copeptin: cross-talk between obesity and acute ischemic stroke initiation and severity in Egyptians.Neurol Sci. 2018 Jun;39(6):1093-1104. doi: 10.1007/s10072-018-3396-0. Epub 2018 Apr 10.
767 Fibro-Adipogenic Remodeling of the Diaphragm in Obesity-Associated Respiratory Dysfunction.Diabetes. 2019 Jan;68(1):45-56. doi: 10.2337/db18-0209. Epub 2018 Oct 25.
768 Thyroid hormone receptor alpha gene variants increase the risk of developing obesity and show gene-diet interactions.Int J Obes (Lond). 2013 Nov;37(11):1499-505. doi: 10.1038/ijo.2013.11. Epub 2013 Feb 12.
769 Inhibition of STAT3 signaling blocks obesity-induced mammary hyperplasia in a mouse model.Am J Cancer Res. 2017 Mar 1;7(3):727-739. eCollection 2017.
770 Toll-like receptor signaling and serum levels of interferon and lipopolysaccharide binding protein are related to abdominal obesity: a case-control study between metabolically healthy and metabolically unhealthy obese individuals.Nutr Res. 2018 Jul;55:11-20. doi: 10.1016/j.nutres.2018.03.014. Epub 2018 Apr 6.
771 Endothelial overexpression of endothelin-1 modulates aortic, carotid, iliac and renal arterial responses in obese mice.Acta Pharmacol Sin. 2017 Apr;38(4):498-512. doi: 10.1038/aps.2016.138. Epub 2017 Feb 20.
772 Functional Gain and Pain Relief After Total Joint Replacement According to Obesity Status.J Bone Joint Surg Am. 2017 Jul 19;99(14):1183-1189. doi: 10.2106/JBJS.16.00960.
773 Decreased TLR3 in Hyperplastic Adipose Tissue, Blood and Inflamed Adipocytes is Related to Metabolic Inflammation.Cell Physiol Biochem. 2018;51(3):1051-1068. doi: 10.1159/000495487. Epub 2018 Nov 26.
774 Microparticles derived from obese adipose tissue elicit a pro-inflammatory phenotype of CD16(+), CCR5(+) and TLR8(+) monocytes.Biochim Biophys Acta Mol Basis Dis. 2017 Jan;1863(1):139-151. doi: 10.1016/j.bbadis.2016.09.016. Epub 2016 Sep 25.
775 Rare genetic diseases with human lean and/or starvation phenotype open new avenues for obesity and type II diabetes treatment.Curr Pharm Biotechnol. 2014;14(13):1093-8. doi: 10.2174/1389201015666140408124559.
776 Height, Obesity, and the Risk of TMPRSS2:ERG-Defined Prostate Cancer.Cancer Epidemiol Biomarkers Prev. 2018 Feb;27(2):193-200. doi: 10.1158/1055-9965.EPI-17-0547. Epub 2017 Nov 22.
777 Matriptase-2 deficiency protects from obesity by modulating iron homeostasis.Nat Commun. 2018 Apr 10;9(1):1350. doi: 10.1038/s41467-018-03853-1.
778 Tumor necrosis-like weak inducer of apoptosis as a proinflammatory cytokine in human adipocyte cells: up-regulation in severe obesity is mediated by inflammation but not hypoxia.J Clin Endocrinol Metab. 2010 Jun;95(6):2983-92. doi: 10.1210/jc.2009-2481. Epub 2010 Apr 9.
779 Elevations of inflammatory proteins in neonatal blood are associated with obesity and overweight among 2-year-old children born extremely premature.Pediatr Res. 2018 Jun;83(6):1110-1119. doi: 10.1038/pr.2017.313. Epub 2018 Jan 10.
780 OX40 promotes obesity-induced adipose inflammation and insulin resistance.Cell Mol Life Sci. 2017 Oct;74(20):3827-3840. doi: 10.1007/s00018-017-2552-7. Epub 2017 Jun 13.
781 Expression of TWEAK and its receptor Fn14 in human subcutaneous adipose tissue. Relationship with other inflammatory cytokines in obesity.Cytokine. 2006 Feb 7;33(3):129-37. doi: 10.1016/j.cyto.2005.12.005. Epub 2006 Feb 28.
782 Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production.Immunol Cell Biol. 2018 Jan;96(1):41-53. doi: 10.1111/imcb.1002. Epub 2017 Nov 23.
783 No impact of obesity susceptibility loci on weight regain after a lifestyle intervention in overweight children.J Pediatr Endocrinol Metab. 2013;26(11-12):1209-13. doi: 10.1515/jpem-2013-0179.
784 Predictors of 10-year changes in levels of N-terminal pro B-type natriuretic peptide and cardiac troponin I in the elderly.Int J Cardiol. 2018 Apr 15;257:300-305. doi: 10.1016/j.ijcard.2017.10.095.
785 Increased expression of triggering receptor expressed on myeloid cells-1 in the population with obesity and insulin resistance.Obesity (Silver Spring). 2017 Mar;25(3):527-538. doi: 10.1002/oby.21714. Epub 2017 Jan 23.
786 Food deprivation during active phase induces skeletal muscle atrophy via IGF-1 reduction in mice.Arch Biochem Biophys. 2019 Nov 30;677:108160. doi: 10.1016/j.abb.2019.108160. Epub 2019 Oct 19.
787 TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in mice.J Hepatol. 2015 Feb;62(2):371-9. doi: 10.1016/j.jhep.2014.09.026. Epub 2014 Oct 2.
788 Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity.Cell. 2016 Jan 28;164(3):353-64. doi: 10.1016/j.cell.2015.12.025.
789 TRPC1 regulates brown adipose tissue activity in a PPAR-dependent manner.Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E825-E832. doi: 10.1152/ajpendo.00170.2017. Epub 2018 Jul 10.
790 COL9A3 gene polymorphism and obesity in intervertebral disc degeneration of the lumbar spine: evidence of gene-environment interaction.Spine (Phila Pa 1976). 2002 Dec 1;27(23):2691-6. doi: 10.1097/00007632-200212010-00008.
791 Free fatty acid-induced H(2)O(2) activates TRPM2 to aggravate endothelial insulin resistance via Ca(2+)-dependent PERK/ATF4/TRB3 cascade in obese mice.Free Radic Biol Med. 2019 Nov 1;143:288-299. doi: 10.1016/j.freeradbiomed.2019.08.018. Epub 2019 Aug 21.
792 TRPM5 in the battle against diabetes and obesity. Acta Physiol (Oxf). 2018 Feb;222(2).
793 Recent Progress in TRPM8 Modulation: An Update.Int J Mol Sci. 2019 May 28;20(11):2618. doi: 10.3390/ijms20112618.
794 Troglitazone activates TRPV1 and causes deacetylation of PPAR in 3T3-L1 cells.Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1;1865(2):445-453. doi: 10.1016/j.bbadis.2018.11.004. Epub 2018 Nov 26.
795 Mutations in MKKS cause Bardet-Biedl syndrome.Nat Genet. 2000 Sep;26(1):15-6. doi: 10.1038/79116.
796 Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity.Cell Metab. 2012 Dec 5;16(6):814-24. doi: 10.1016/j.cmet.2012.11.005.
797 UBE3A Suppresses Overnutrition-Induced Expression of the Steatosis Target Genes of MLL4 by Degrading MLL4.Hepatology. 2019 Mar;69(3):1122-1134. doi: 10.1002/hep.30284. Epub 2019 Feb 7.
798 Genome-wide analysis of hepatic lipid content in extreme obesity.Acta Diabetol. 2015 Apr;52(2):373-82. doi: 10.1007/s00592-014-0654-3. Epub 2014 Sep 23.
799 ULK1 prevents cardiac dysfunction in obesity through autophagy-meditated regulation of lipid metabolism.Cardiovasc Res. 2017 Aug 1;113(10):1137-1147. doi: 10.1093/cvr/cvx064.
800 Ubiquitin-Specific Peptidase 10 (USP10) Inhibits Hepatic Steatosis, Insulin Resistance, and Inflammation Through Sirt6.Hepatology. 2018 Nov;68(5):1786-1803. doi: 10.1002/hep.30062. Epub 2018 Sep 17.
801 Comparative understanding of UTS2 and UTS2R genes for their involvement in type 2 diabetes mellitus.Int J Biol Sci. 2008 Apr 23;4(2):96-102. doi: 10.7150/ijbs.4.96.
802 Late gestational testosterone exposure causes glucose deregulation and elevated cardiac VCAM-1 and DPP-4 activity in rats.Arch Physiol Biochem. 2021 Oct;127(5):445-452. doi: 10.1080/13813455.2019.1650068. Epub 2019 Aug 7.
803 Polymorphisms of VKORC1 and CYP2C9 are associated with warfarin sensitivity in Chinese population.Ther Clin Risk Manag. 2017 Mar 31;13:421-425. doi: 10.2147/TCRM.S130198. eCollection 2017.
804 Therapeutic potential of cannabinoids in CNS disease.CNS Drugs. 2003;17(3):179-202. doi: 10.2165/00023210-200317030-00004.
805 Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases.Sci Transl Med. 2019 Sep 18;11(510):eaav5055. doi: 10.1126/scitranslmed.aav5055.
806 Wnt7a promotes wound healing by regulation of angiogenesis and inflammation: Issues on diabetes and obesity.J Dermatol Sci. 2018 Feb 15:S0923-1811(18)30103-8. doi: 10.1016/j.jdermsci.2018.02.007. Online ahead of print.
807 The non-synonymous polymorphism at position 114 of the WRN protein affects cholesterol efflux in vitro and correlates with cholesterol levels in vivo.Exp Gerontol. 2013 Jun;48(6):533-8. doi: 10.1016/j.exger.2013.03.003. Epub 2013 Mar 21.
808 Combination of WAGR and Potocki-Shaffer contiguous deletion syndromes in a patient with an 11p11.2-p14 deletion.Eur J Hum Genet. 2005 Apr;13(4):409-13. doi: 10.1038/sj.ejhg.5201358.
809 Independent links between plasma xanthine oxidoreductase activity and levels of adipokines.J Diabetes Investig. 2019 Jul;10(4):1059-1067. doi: 10.1111/jdi.12982. Epub 2019 Jan 28.
810 RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism.J Clin Invest. 2017 Oct 2;127(10):3741-3754. doi: 10.1172/JCI94029. Epub 2017 Sep 11.
811 The second point mutation in PREPL: a case report and literature review. J Hum Genet. 2018 May;63(5):677-681. doi: 10.1038/s10038-018-0426-y. Epub 2018 Feb 26.
812 Environmental Pollutants Effect on Brown Adipose Tissue.Front Physiol. 2019 Jan 9;9:1891. doi: 10.3389/fphys.2018.01891. eCollection 2018.
813 Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1.Obesity (Silver Spring). 2019 Aug;27(8):1292-1304. doi: 10.1002/oby.22521.
814 The Root of Atractylodes macrocephala Koidzumi Prevents Obesity and Glucose Intolerance and Increases Energy Metabolism in Mice.Int J Mol Sci. 2018 Jan 17;19(1):278. doi: 10.3390/ijms19010278.
815 P4 ATPases - lipid flippases and their role in disease.Biochim Biophys Acta. 2009 Jul;1791(7):628-35. doi: 10.1016/j.bbalip.2009.02.008. Epub 2009 Feb 27.
816 Genomic variants at 20p11 associated with body fat mass in the European population.Obesity (Silver Spring). 2017 Apr;25(4):757-764. doi: 10.1002/oby.21775. Epub 2017 Feb 22.
817 Single nucleotide polymorphisms in protein tyrosine phosphatase 1beta (PTPN1) are associated with essential hypertension and obesity.Hum Mol Genet. 2004 Sep 1;13(17):1885-92. doi: 10.1093/hmg/ddh196. Epub 2004 Jun 30.
818 Resting Energy Expenditure, Insulin Resistance and UCP1 Expression in Human Subcutaneous and Visceral Adipose Tissue of Patients With Obesity.Front Endocrinol (Lausanne). 2019 Aug 7;10:548. doi: 10.3389/fendo.2019.00548. eCollection 2019.
819 Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.Diabetologia. 2016 Apr;59(4):799-812. doi: 10.1007/s00125-015-3852-9. Epub 2016 Jan 11.
820 Effect of pre-existing maternal obesity, gestational diabetes and adipokines on the expression of genes involved in lipid metabolism in adipose tissue.Metabolism. 2014 Feb;63(2):250-62. doi: 10.1016/j.metabol.2013.10.001. Epub 2013 Oct 24.
821 Hypoglycemic Effects of Pyrodextrins with Different Molecular Weights and Digestibilities in Mice with Diet-Induced Obesity.J Agric Food Chem. 2018 Mar 21;66(11):2988-2995. doi: 10.1021/acs.jafc.8b00404. Epub 2018 Mar 6.
822 Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - a preliminary report. Oncotarget. 2018 May 22;9(39):25557-25571.
823 Understanding intestinal glucose transporter expression in obese compared to non-obese subjects.Surg Endosc. 2018 Apr;32(4):1755-1761. doi: 10.1007/s00464-017-5858-5. Epub 2017 Sep 21.
824 Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis.Genome Res. 2011 Jul;21(7):1065-73. doi: 10.1101/gr.120741.111. Epub 2011 Apr 19.
825 Role of Zinc Homeostasis in the Pathogenesis of Diabetes and Obesity.Int J Mol Sci. 2018 Feb 6;19(2):476. doi: 10.3390/ijms19020476.
826 Global correlation analysis for microRNA and gene expression profiles in human obesity.Pathol Res Pract. 2015 May;211(5):361-8. doi: 10.1016/j.prp.2014.11.014. Epub 2015 Jan 14.
827 SGLT6 - A pharmacological target for the treatment of obesity?.Adipocyte. 2018;7(4):277-284. doi: 10.1080/21623945.2018.1516098. Epub 2018 Oct 11.
828 Modelling BMI trajectories in children for genetic association studies.PLoS One. 2013;8(1):e53897. doi: 10.1371/journal.pone.0053897. Epub 2013 Jan 17.
829 Catestatin Inhibits Obesity-Induced Macrophage Infiltration and Inflammation in the Liver and Suppresses Hepatic Glucose Production, Leading to Improved Insulin Sensitivity.Diabetes. 2018 May;67(5):841-848. doi: 10.2337/db17-0788. Epub 2018 Feb 6.
830 Paraoxonases-1, -2 and -3: what are their functions? Chem Biol Interact. 2016 Nov 25;259(Pt B):51-62.
831 L-PGDS-produced PGD(2) in premature, but not in mature, adipocytes increases obesity and insulin resistance.Sci Rep. 2019 Feb 13;9(1):1931. doi: 10.1038/s41598-018-38453-y.
832 Familial clustering of metabolic phenotype in brothers of women with polycystic ovary syndrome.Gynecol Endocrinol. 2019 Jul;35(7):601-603. doi: 10.1080/09513590.2019.1566451. Epub 2019 Feb 6.
833 Diet-induced obese alters the expression and function of hepatic drug-metabolizing enzymes and transporters in rats.Biochem Pharmacol. 2019 Jun;164:368-376. doi: 10.1016/j.bcp.2019.05.002. Epub 2019 May 4.
834 Hypovitaminosis D: Is It Time to Consider the Use of Calcifediol?.Nutrients. 2019 May 6;11(5):1016. doi: 10.3390/nu11051016.
835 Post genome-wide gene-environment interaction study: The effect of genetically driven insulin resistance on breast cancer risk using Mendelian randomization.PLoS One. 2019 Jun 27;14(6):e0218917. doi: 10.1371/journal.pone.0218917. eCollection 2019.
836 Outcomes in Cardiogenic Shock from Acute Coronary Syndrome Depending on Severity of Obesity.Am J Cardiol. 2019 Apr 15;123(8):1267-1272. doi: 10.1016/j.amjcard.2019.01.010. Epub 2019 Jan 24.
837 Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES).PLoS One. 2015 Apr 1;10(4):e0119941. doi: 10.1371/journal.pone.0119941. eCollection 2015.
838 Intra-adipose sex steroid metabolism and body fat distribution in idiopathic human obesity.Clin Endocrinol (Oxf). 2007 Mar;66(3):440-6. doi: 10.1111/j.1365-2265.2007.02755.x.
839 Knockout of arsenic (+3 oxidation state) methyltransferase is associated with adverse metabolic phenotype in mice: the role of sex and arsenic exposure.Arch Toxicol. 2017 Jul;91(7):2617-2627. doi: 10.1007/s00204-016-1890-9. Epub 2016 Nov 15.
840 HYPOTHesizing about central comBAT against obesity.J Physiol Biochem. 2020 May;76(2):193-211. doi: 10.1007/s13105-019-00719-y. Epub 2019 Dec 16.
841 Skeletal Muscle Phospholipid Metabolism Regulates Insulin Sensitivity and Contractile Function.Diabetes. 2016 Feb;65(2):358-70. doi: 10.2337/db15-0659. Epub 2015 Oct 28.
842 Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance.Cell Rep. 2017 Jan 17;18(3):636-646. doi: 10.1016/j.celrep.2016.12.070.
843 Effects of familial hypercholesterolemia-associated genes on the phenotype of premature myocardial infarction.Lipids Health Dis. 2019 Apr 11;18(1):95. doi: 10.1186/s12944-019-1042-3.
844 Regulation of 11beta-HSD genes in human adipose tissue: influence of central obesity and weight loss.Obes Res. 2004 Jan;12(1):9-17. doi: 10.1038/oby.2004.3.
845 Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells.Biosci Rep. 2019 Mar 22;39(3):BSR20181155. doi: 10.1042/BSR20181155. Print 2019 Mar 29.
846 Impact of Body Mass Index and Genetics on Warfarin Major Bleeding Outcomes in a Community Setting.Am J Med. 2017 Feb;130(2):222-228. doi: 10.1016/j.amjmed.2016.08.017. Epub 2016 Sep 2.
847 p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation.J Biol Chem. 2011 Aug 12;286(32):28343-56. doi: 10.1074/jbc.M111.254227. Epub 2011 Jun 9.
848 A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice.PLoS One. 2016 Nov 10;11(11):e0166198. doi: 10.1371/journal.pone.0166198. eCollection 2016.
849 Minor diplotypes of FMO3 might protect children and adolescents from obesity and insulin resistance.Int J Obes (Lond). 2018 Jun;42(6):1243-1248. doi: 10.1038/s41366-018-0100-7. Epub 2018 May 24.
850 Host susceptibility to severe influenza A virus infection.Crit Care. 2019 Sep 5;23(1):303. doi: 10.1186/s13054-019-2566-7.
851 Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction.Diabetes. 2010 May;59(5):1132-42. doi: 10.2337/db09-1105. Epub 2010 Feb 11.
852 Concomitance of Polymorphisms in Glutathione Transferase Omega Genes Is Associated with Risk of Clear Cell Renal Cell Carcinoma.Tohoku J Exp Med. 2018 Sep;246(1):35-44. doi: 10.1620/tjem.246.35.
853 Interactions between RASA2, CADM1, HIF1AN gene polymorphisms and body fatness with breast cancer: a population-based case-control study in China.Oncotarget. 2017 Oct 5;8(58):98258-98269. doi: 10.18632/oncotarget.21530. eCollection 2017 Nov 17.
854 The Expression of Aldolase B in Islets Is Negatively Associated With Insulin Secretion in Humans.J Clin Endocrinol Metab. 2018 Dec 1;103(12):4373-4383. doi: 10.1210/jc.2018-00791.
855 Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks.Nat Genet. 2009 Apr;41(4):415-23. doi: 10.1038/ng.325. Epub 2009 Mar 8.
856 Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans.Hum Mol Genet. 2012 Oct 15;21(20):4530-6. doi: 10.1093/hmg/dds282. Epub 2012 Jul 12.
857 Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing.PLoS One. 2016 Feb 1;11(2):e0147904. doi: 10.1371/journal.pone.0147904. eCollection 2016.
858 Association of anti-obesity activity of N-acetylcysteine with metallothionein-II down-regulation.Exp Mol Med. 2006 Apr 30;38(2):162-72. doi: 10.1038/emm.2006.20.
859 Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase.Bioorg Med Chem Lett. 2018 Mar 1;28(5):922-925. doi: 10.1016/j.bmcl.2018.01.058. Epub 2018 Jan 31.
860 Aging and erectile function.Aging Male. 2020 Dec;23(5):1115-1124. doi: 10.1080/13685538.2019.1686756. Epub 2019 Nov 14.
861 Adipose hypothermia in obesity and its association with period homolog 1, insulin sensitivity, and inflammation in fat.PLoS One. 2014 Nov 14;9(11):e112813. doi: 10.1371/journal.pone.0112813. eCollection 2014.
862 The Effect of One Anastomosis Gastric Bypass on Branched-Chain Fatty Acid and Branched-Chain Amino Acid Metabolism in Subjects with Morbid Obesity.Obes Surg. 2020 Jan;30(1):304-312. doi: 10.1007/s11695-019-04157-z.
863 Combined Omics Reveals That Disruption of the Selenocysteine Lyase Gene Affects Amino Acid Pathways in Mice.Nutrients. 2019 Oct 26;11(11):2584. doi: 10.3390/nu11112584.
864 Pharmacogenetics of soluble sulfotransferases (SULTs).Naunyn Schmiedebergs Arch Pharmacol. 2004 Jan;369(1):55-68. doi: 10.1007/s00210-003-0826-0. Epub 2003 Nov 5.
865 Estrogen sulfotransferase is expressed in subcutaneous adipose tissue of obese humans in association with TNF-alpha and SOCS3.J Clin Endocrinol Metab. 2011 Jul;96(7):E1153-8. doi: 10.1210/jc.2010-2903. Epub 2011 May 4.
866 The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice.Obesity (Silver Spring). 2018 Aug;26(8):1303-1311. doi: 10.1002/oby.22206. Epub 2018 Jul 2.
867 Genetic obesity affects neural ketone body utilization in the rat brain.Obesity (Silver Spring). 2009 Mar;17(3):611-5. doi: 10.1038/oby.2008.566. Epub 2008 Dec 11.
868 Hypothalamic expression of the atypical chemokine receptor ACKR2 is involved in the systemic regulation of glucose tolerance.Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1126-1137. doi: 10.1016/j.bbadis.2019.01.001. Epub 2019 Feb 7.
869 Insulin Regulates Lipolysis and Fat Mass by Upregulating Growth/Differentiation Factor 3 in Adipose Tissue Macrophages.Diabetes. 2018 Sep;67(9):1761-1772. doi: 10.2337/db17-1201. Epub 2018 Jun 26.
870 Hyperphagia-mediated obesity in transgenic mice misexpressing the RNA-editing enzyme ADAR2.J Biol Chem. 2007 Aug 3;282(31):22448-59. doi: 10.1074/jbc.M700265200. Epub 2007 Jun 12.
871 New ADCY3 Variants Dance in Obesity Etiology.Trends Endocrinol Metab. 2018 Jun;29(6):361-363. doi: 10.1016/j.tem.2018.02.004. Epub 2018 Feb 14.
872 Regulation of hepatic apolipoprotein B RNA editing in the genetically obese Zucker rat.Metabolism. 1996 Sep;45(9):1056-8. doi: 10.1016/s0026-0495(96)90001-3.
873 Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification.J Lipid Res. 2007 Jun;48(6):1353-61. doi: 10.1194/jlr.M700024-JLR200. Epub 2007 Mar 5.
874 Healthy diet is associated with gene expression in blood: the Framingham Heart Study.Am J Clin Nutr. 2019 Sep 1;110(3):742-749. doi: 10.1093/ajcn/nqz060.
875 Pseudohypoparathyroidism vs. tricho-rhino-phalangeal syndrome: patient reclassification.J Pediatr Endocrinol Metab. 2014 Nov;27(11-12):1089-94. doi: 10.1515/jpem-2014-0020.
876 Gaps in provider lifestyle counseling and its adherence among obese adults with prediabetes and diabetes in the United States.Prev Med. 2019 Dec;129:105815. doi: 10.1016/j.ypmed.2019.105815. Epub 2019 Aug 24.
877 More activated cardiac mitochondrial-dependent apoptotic pathway in obese Zucker rats.Obesity (Silver Spring). 2007 Nov;15(11):2634-42. doi: 10.1038/oby.2007.315.
878 Association of CTRP13 With Liver Enzymes and Cognitive Symptoms in Nonalcoholic Fatty Liver Disease.Nurs Res. 2019 Jan/Feb;68(1):29-38. doi: 10.1097/NNR.0000000000000319.
879 Circulating CTRP6 Levels are Increased in Overweight or Obese Chinese Individuals and Associated with Insulin Resistance Parameters: A Pilot Study.Exp Clin Endocrinol Diabetes. 2021 Jul;129(7):535-541. doi: 10.1055/a-0929-6072. Epub 2019 Aug 14.
880 Interaction between Calpain 5, Peroxisome proliferator-activated receptor-gamma and Peroxisome proliferator-activated receptor-delta genes: a polygenic approach to obesity.Cardiovasc Diabetol. 2008 Jul 25;7:23. doi: 10.1186/1475-2840-7-23.
881 Dietary obesity increases NO and inhibits BKCa-mediated, endothelium-dependent dilation in rat cremaster muscle artery: association with caveolins and caveolae.Am J Physiol Heart Circ Physiol. 2012 Jun 15;302(12):H2464-76. doi: 10.1152/ajpheart.00965.2011. Epub 2012 Apr 6.
882 Serum CCN3 levels are increased in type 2 diabetes mellitus and associated with obesity, insulin resistance and inflammation.Clin Chim Acta. 2019 Jul;494:52-57. doi: 10.1016/j.cca.2019.03.006. Epub 2019 Mar 13.
883 Adipocyte CD1d determines adipose inflammation and insulin resistance in obesity.Adipocyte. 2018;7(2):129-136. doi: 10.1080/21623945.2018.1440928. Epub 2018 Mar 6.
884 Plasma protein biomarkers and their association with mutually exclusive cardiovascular phenotypes: the FIBRO-TARGETS case-control analyses.Clin Res Cardiol. 2020 Jan;109(1):22-33. doi: 10.1007/s00392-019-01480-4. Epub 2019 May 6.
885 The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach.Mol Metab. 2019 Mar;21:36-50. doi: 10.1016/j.molmet.2018.12.008. Epub 2019 Jan 2.
886 Lentivirus-mediated CTRP6 silencing ameliorates diet-induced obesity in mice.Exp Cell Res. 2018 Jun 1;367(1):15-23. doi: 10.1016/j.yexcr.2018.01.027. Epub 2018 Jan 31.
887 Antiretroviral drug-induced endothelial dysfunction is improved by dual PPAR/ stimulation in obesity.Vascul Pharmacol. 2019 Oct;121:106577. doi: 10.1016/j.vph.2019.106577. Epub 2019 Jul 5.
888 CYP2W1, CYP4F11 and CYP8A1 polymorphisms and interaction of CYP2W1 genotypes with risk factors in Mexican women with breast cancer.Asian Pac J Cancer Prev. 2012;13(3):837-46. doi: 10.7314/apjcp.2012.13.3.837.
889 Oxidative Phosphorylation Impairment by DDT and DDE.Front Endocrinol (Lausanne). 2019 Mar 12;10:122. doi: 10.3389/fendo.2019.00122. eCollection 2019.
890 Nucleotide sequence and expression of rat beta-defensin-1: its significance in diabetic rodent models.Nephron. 2001 May;88(1):65-70. doi: 10.1159/000045961.
891 Roux-en-Y gastric bypass surgery restores insulin-mediated glucose partitioning and mitochondrial dynamics in primary myotubes from severely obese humans.Int J Obes (Lond). 2020 Mar;44(3):684-696. doi: 10.1038/s41366-019-0469-y. Epub 2019 Oct 17.
892 DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle.Diabetologia. 2019 May;62(5):845-859. doi: 10.1007/s00125-019-4824-2. Epub 2019 Feb 1.
893 Differential expression of adipose tissue proteins between obesity-susceptible and -resistant rats fed a high-fat diet.Proteomics. 2011 Apr;11(8):1429-48. doi: 10.1002/pmic.201000515. Epub 2011 Feb 25.
894 The role of bioactives in energy metabolism and metabolic syndrome.Proc Nutr Soc. 2019 Aug;78(3):340-350. doi: 10.1017/S0029665119000545. Epub 2019 Apr 10.
895 The coexistence of nocturnal sustained hypoxia and obesity additively increases cardiac apoptosis.J Appl Physiol (1985). 2008 Apr;104(4):1144-53. doi: 10.1152/japplphysiol.00152.2007. Epub 2008 Jan 17.
896 Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism.Sci Rep. 2017 Jul 13;7(1):5305. doi: 10.1038/s41598-017-05597-2.
897 High circulating follistatin-like protein 1 as a biomarker of a metabolically unhealthy state.Endocr J. 2019 Mar 28;66(3):241-251. doi: 10.1507/endocrj.EJ18-0352. Epub 2019 Feb 8.
898 Evaluation of Bacillus subtilis SPB1 biosurfactant effects on hyperglycemia, angiotensin I-converting enzyme (ACE) activity and kidney function in rats fed on high-fat-high-fructose diet.Arch Physiol Biochem. 2017 May;123(2):112-120. doi: 10.1080/13813455.2016.1261902. Epub 2016 Dec 25.
899 GALNT2 expression is reduced in patients with Type 2 diabetes: possible role of hyperglycemia.PLoS One. 2013 Jul 22;8(7):e70159. doi: 10.1371/journal.pone.0070159. Print 2013.
900 Circulating GDF11 levels are decreased with age but are unchanged with obesity and type 2 diabetes.Aging (Albany NY). 2019 Mar 21;11(6):1733-1744. doi: 10.18632/aging.101865.
901 Regulated expression of Gemin5, Xrn1, Cpeb and Stau1 in the uterus and ovaries after superovulation and the effect of exogenous estradiol and leptin in rodents.Mol Biol Rep. 2019 Apr;46(2):2533-2540. doi: 10.1007/s11033-019-04606-z. Epub 2019 Jan 28.
902 Genetic and Epigenetic Defects at the GNAS Locus Lead to Distinct Patterns of Skeletal Growth but Similar Early-Onset Obesity.J Bone Miner Res. 2018 Aug;33(8):1480-1488. doi: 10.1002/jbmr.3450. Epub 2018 Jun 7.
903 Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM.Diabetes. 1997 Mar;46(3):408-13. doi: 10.2337/diab.46.3.408.
904 Interaction between obesity and the Hypoxia Inducible Factor 3 Alpha Subunit rs3826795 polymorphism in relation with plasma alanine aminotransferase.BMC Med Genet. 2017 Jul 28;18(1):80. doi: 10.1186/s12881-017-0437-0.
905 Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice.Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1451-1459. doi: 10.1016/j.bbadis.2019.02.017. Epub 2019 Feb 22.
906 TNF- Upregulates IKK Expression via the Lin28B/let-7a Pathway to Induce Catecholamine Resistance in Adipocytes.Obesity (Silver Spring). 2019 May;27(5):767-776. doi: 10.1002/oby.22434. Epub 2019 Apr 1.
907 Review: the Roles and Mechanisms of Glycoprotein 130 Cytokines in the Regulation of Adipocyte Biological Function.Inflammation. 2019 Jun;42(3):790-798. doi: 10.1007/s10753-019-00959-6.
908 Investigation of the association between obesity and insulin-induced gene 1 polymorphism at 7q36.3 region in Uygur population in Xinjiang, China.Biosci Rep. 2019 Dec 20;39(12):BSR20190498. doi: 10.1042/BSR20190498.
909 Akt activation: A potential strategy to ameliorate insulin resistance.Diabetes Res Clin Pract. 2019 Oct;156:107092. doi: 10.1016/j.diabres.2017.10.004. Epub 2017 Oct 28.
910 Increased Adipose Tissue Expression of Interferon Regulatory Factor (IRF)-5 in Obesity: Association with Metabolic Inflammation.Cells. 2019 Nov 11;8(11):1418. doi: 10.3390/cells8111418.
911 Affective Pavlovian motivation is enhanced in obesity susceptible populations: Implications for incentive motivation in obesity.Behav Brain Res. 2020 Feb 17;380:112318. doi: 10.1016/j.bbr.2019.112318. Epub 2019 Nov 21.
912 Adipose KLF15 Controls Lipid Handling to Adapt to Nutrient Availability.Cell Rep. 2017 Dec 12;21(11):3129-3140. doi: 10.1016/j.celrep.2017.11.032.
913 Leptin and Leptin receptor polymorphisms, plasma Leptin levels and obesity in Tunisian volunteers.Int J Exp Pathol. 2018 Jun;99(3):121-130. doi: 10.1111/iep.12271. Epub 2018 Jun 11.
914 Plasma levels of ghrelin, des-acyl ghrelin and LEAP2 in children with obesity: correlation with age and insulin resistance.Eur J Endocrinol. 2020 Feb;182(2):165-175. doi: 10.1530/EJE-19-0684.
915 Lipin-2 reduces proinflammatory signaling induced by saturated fatty acids in macrophages.J Biol Chem. 2012 Mar 30;287(14):10894-904. doi: 10.1074/jbc.M112.342915. Epub 2012 Feb 8.
916 The genetic and epigenetic association of LDL Receptor Related Protein 1B (LRP1B) gene with childhood obesity.Sci Rep. 2019 Feb 12;9(1):1815. doi: 10.1038/s41598-019-38538-2.
917 SWELL signalling in adipocytes: can fat 'feel' fat?.Adipocyte. 2019 Dec;8(1):223-228. doi: 10.1080/21623945.2019.1612223.
918 Multidisciplinary Roles of LRRFIP1/GCF2 in Human Biological Systems and Diseases.Cells. 2019 Jan 31;8(2):108. doi: 10.3390/cells8020108.
919 Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21.Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2125-2137. doi: 10.1016/j.bbadis.2019.04.010. Epub 2019 Apr 26.
920 MIP-1 Induction by Palmitate in the Human Monocytic Cells Implicates TLR4 Signaling Mechanism.Cell Physiol Biochem. 2019;52(2):212-224. doi: 10.33594/000000015. Epub 2019 Feb 28.
921 The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation.Mol Metab. 2019 May;23:14-23. doi: 10.1016/j.molmet.2019.02.003. Epub 2019 Feb 20.
922 Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension.Nat Med. 2019 Nov;25(11):1733-1738. doi: 10.1038/s41591-019-0622-0. Epub 2019 Nov 7.
923 Adipose-derived Mesenchymal Stem Cells in the Treatment of Obesity: A Systematic Review of Longitudinal Studies on Preclinical Evidence.Curr Stem Cell Res Ther. 2018;13(6):466-475. doi: 10.2174/1574888X13666180515160008.
924 The skeletal muscle Wnt pathway may modulate insulin resistance and muscle development in a diet-induced obese rat model.Obesity (Silver Spring). 2012 Aug;20(8):1577-84. doi: 10.1038/oby.2012.42. Epub 2012 Feb 21.
925 Satellite cell proliferation is reduced in muscles of obese Zucker rats but restored with loading.Am J Physiol Cell Physiol. 2008 Aug;295(2):C521-8. doi: 10.1152/ajpcell.00073.2008. Epub 2008 May 28.
926 Flow-induced remodeling in resistance arteries from obese Zucker rats is associated with endothelial dysfunction.Hypertension. 2007 Jul;50(1):248-54. doi: 10.1161/HYPERTENSIONAHA.107.088716. Epub 2007 May 21.
927 The Prader-Willi syndrome proteins MAGEL2 and necdin regulate leptin receptor cell surface abundance through ubiquitination pathways.Hum Mol Genet. 2017 Nov 1;26(21):4215-4230. doi: 10.1093/hmg/ddx311.
928 A high-sucrose isocaloric pair-fed model induces obesity and impairs NDUFB6 gene function in rat adipose tissue.J Nutrigenet Nutrigenomics. 2009;2(6):267-72. doi: 10.1159/000308465. Epub 2010 Jun 19.
929 Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome.J Clin Invest. 2017 Jan 3;127(1):293-305. doi: 10.1172/JCI88648. Epub 2016 Dec 12.
930 Temporal Control of Metabolic Amplitude by Nocturnin.Cell Rep. 2018 Jan 30;22(5):1225-1235. doi: 10.1016/j.celrep.2018.01.011.
931 The Extending Spectrum of NPC1-Related Human Disorders: From Niemann-Pick C1 Disease to Obesity.Endocr Rev. 2018 Apr 1;39(2):192-220. doi: 10.1210/er.2017-00176.
932 P110 in the ventromedial hypothalamus regulates glucose and energy metabolism.Exp Mol Med. 2019 Apr 26;51(4):1-9. doi: 10.1038/s12276-019-0249-8.
933 FLT1 and transcriptome-wide polyadenylation site (PAS) analysis in preeclampsia.Sci Rep. 2017 Sep 22;7(1):12139. doi: 10.1038/s41598-017-11639-6.
934 Effect of NUCKS-1 overexpression on cytokine profiling in obese women with breast cancer.Asian Pac J Cancer Prev. 2014;15(2):837-45. doi: 10.7314/apjcp.2014.15.2.837.
935 Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity.Mol Metab. 2018 May;11:160-177. doi: 10.1016/j.molmet.2018.02.010. Epub 2018 Feb 24.
936 Quantitative bias analysis of the association of type 2 diabetes mellitus with 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153).Environ Int. 2019 Apr;125:291-299. doi: 10.1016/j.envint.2018.12.036. Epub 2019 Feb 5.
937 Obesity and diabetes in transgenic mice expressing proSAAS.J Endocrinol. 2004 Mar;180(3):357-68. doi: 10.1677/joe.0.1800357.
938 Higher PDCD4 expression is associated with obesity, insulin resistance, lipid metabolism disorders, and granulosa cell apoptosis in polycystic ovary syndrome.Fertil Steril. 2016 May;105(5):1330-1337.e3. doi: 10.1016/j.fertnstert.2016.01.020. Epub 2016 Feb 8.
939 CLOCK, PER2 and BMAL1 DNA methylation: association with obesity and metabolic syndrome characteristics and monounsaturated fat intake.Chronobiol Int. 2012 Nov;29(9):1180-94. doi: 10.3109/07420528.2012.719967. Epub 2012 Sep 24.
940 Phosphatidylinositol 3-kinase/Akt signaling stimulates colonic mucosal cell survival during aging.Am J Physiol Gastrointest Liver Physiol. 2006 Jan;290(1):G49-55. doi: 10.1152/ajpgi.00106.2005. Epub 2005 Aug 25.
941 Obesity is associated with altered gene expression in human tastebuds.Int J Obes (Lond). 2019 Jul;43(7):1475-1484. doi: 10.1038/s41366-018-0303-y. Epub 2019 Jan 29.
942 Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling.Diabetologia. 2011 Aug;54(8):2122-31. doi: 10.1007/s00125-011-2173-x. Epub 2011 May 12.
943 Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3).Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13296-301. doi: 10.1073/pnas.0405354101. Epub 2004 Aug 24.
944 Nociceptin/orphanin FQ modulates energy homeostasis through inhibition of neurotransmission at VMN SF-1/ARC POMC synapses in a sex- and diet-dependent manner.Biol Sex Differ. 2019 Feb 12;10(1):9. doi: 10.1186/s13293-019-0220-3.
945 Identification of a 1p21 independent functional variant for abdominal obesity.Int J Obes (Lond). 2019 Dec;43(12):2480-2490. doi: 10.1038/s41366-019-0350-z. Epub 2019 Apr 3.
946 Bioelectrical impedance vector analysis in obese and overweight children.PLoS One. 2019 Jan 24;14(1):e0211148. doi: 10.1371/journal.pone.0211148. eCollection 2019.
947 Sarcopenic obesity is associated with a faster decline in renal function in people with type 2 diabetes.Diabet Med. 2020 Jan;37(1):105-113. doi: 10.1111/dme.14153. Epub 2019 Oct 30.
948 Diet-induced macrophage inhibitory cytokine 1 promotes prostate cancer progression.Endocr Relat Cancer. 2013 Dec 16;21(1):39-50. doi: 10.1530/ERC-13-0227. Print 2014 Feb.
949 Mice without the regulator gene Rsc1A1 exhibit increased Na+-D-glucose cotransport in small intestine and develop obesity.Mol Cell Biol. 2005 Jan;25(1):78-87. doi: 10.1128/MCB.25.1.78-87.2005.
950 High-Fat-Diet-Induced Obesity Produces Spontaneous Ventricular Arrhythmias and Increases the Activity of Ryanodine Receptors in Mice.Int J Mol Sci. 2018 Feb 10;19(2):533. doi: 10.3390/ijms19020533.
951 Relationship between Selenium and Hematological Markers in Young Adults with Normal Weight or Overweight/Obesity.Antioxidants (Basel). 2019 Oct 8;8(10):463. doi: 10.3390/antiox8100463.
952 Peptide vaccine for semaphorin3E ameliorates systemic glucose intolerance in mice with dietary obesity.Sci Rep. 2019 Mar 7;9(1):3858. doi: 10.1038/s41598-019-40325-y.
953 Mechanism of SEMA3G knockdown-mediated attenuation of high-fat diet-induced obesity.J Endocrinol. 2020 Jan;244(1):223-236. doi: 10.1530/JOE-19-0029.
954 Insulin induces expression of the hepatic vaspin gene.Endocr J. 2020 Jan 28;67(1):9-14. doi: 10.1507/endocrj.EJ19-0276. Epub 2019 Sep 4.
955 Diminished lung compliance and elevated surfactant lipids and proteins in nutritionally obese young rats.Lung. 2004;182(2):101-17. doi: 10.1007/s00408-003-1048-4.
956 Morning exercise mitigates the impact of prolonged sitting on cerebral blood flow in older adults.J Appl Physiol (1985). 2019 Apr 1;126(4):1049-1055. doi: 10.1152/japplphysiol.00001.2019. Epub 2019 Feb 7.
957 Genomics of post-prandial lipidomic phenotypes in the Genetics of Lipid lowering Drugs and Diet Network (GOLDN) study.PLoS One. 2014 Jun 6;9(6):e99509. doi: 10.1371/journal.pone.0099509. eCollection 2014.
958 Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins.J Clin Endocrinol Metab. 2004 Sep;89(9):4414-21. doi: 10.1210/jc.2004-0153.
959 Spred2 Regulates High Fat Diet-Induced Adipose Tissue Inflammation, and Metabolic Abnormalities in Mice.Front Immunol. 2019 Jan 22;10:17. doi: 10.3389/fimmu.2019.00017. eCollection 2019.
960 Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats.Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E175-87. doi: 10.1152/ajpendo.00203.2010. Epub 2010 Oct 26.
961 Liver kinase B1 induces browning phenotype in 3T3-L1 adipocytes.Gene. 2019 Jan 15;682:33-41. doi: 10.1016/j.gene.2018.10.012. Epub 2018 Oct 6.
962 Novel Adipokine, FAM19A5, Inhibits Neointima Formation After Injury Through Sphingosine-1-Phosphate Receptor 2.Circulation. 2018 Jul 3;138(1):48-63. doi: 10.1161/CIRCULATIONAHA.117.032398. Epub 2018 Feb 16.
963 Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects.PLoS One. 2016 Feb 11;11(2):e0147468. doi: 10.1371/journal.pone.0147468. eCollection 2016.
964 Catalpol induces autophagy and attenuates liver steatosis in ob/ob and high-fat diet-induced obese mice.Aging (Albany NY). 2019 Nov 7;11(21):9461-9477. doi: 10.18632/aging.102396. Epub 2019 Nov 7.
965 Thrap3 docks on phosphoserine 273 of PPAR and controls diabetic gene programming.Genes Dev. 2014 Nov 1;28(21):2361-9. doi: 10.1101/gad.249367.114. Epub 2014 Oct 14.
966 Thy1 (CD90) expression is regulated by DNA methylation during adipogenesis.FASEB J. 2019 Mar;33(3):3353-3363. doi: 10.1096/fj.201801481R. Epub 2018 Oct 30.
967 Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism.Genes Dev. 2019 Jul 1;33(13-14):747-762. doi: 10.1101/gad.321059.118. Epub 2019 May 23.
968 Remodeling of the residual gastric mucosa after roux-en-y gastric bypass or vertical sleeve gastrectomy in diet-induced obese rats.PLoS One. 2015 Mar 30;10(3):e0121414. doi: 10.1371/journal.pone.0121414. eCollection 2015.
969 A combination of resveratrol and quercetin induces browning in white adipose tissue of rats fed an obesogenic diet.Obesity (Silver Spring). 2017 Jan;25(1):111-121. doi: 10.1002/oby.21706. Epub 2016 Nov 22.
970 NFE2 Induces miR-423-5p to Promote Gluconeogenesis and Hyperglycemia by Repressing the Hepatic FAM3A-ATP-Akt Pathway.Diabetes. 2017 Jul;66(7):1819-1832. doi: 10.2337/db16-1172. Epub 2017 Apr 14.
971 The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes.J Pharmacol Exp Ther. 2017 Jul;362(1):24-30. doi: 10.1124/jpet.117.241281. Epub 2017 Apr 24.
972 Germline gain-of-function mutations in AFF4 cause a developmental syndrome functionally linking the super elongation complex and cohesin. Nat Genet. 2015 Apr;47(4):338-44. doi: 10.1038/ng.3229. Epub 2015 Mar 2.
973 Deficiency in AIM2 induces inflammation and adipogenesis in white adipose tissue leading to obesity and insulin resistance.Diabetologia. 2019 Dec;62(12):2325-2339. doi: 10.1007/s00125-019-04983-x. Epub 2019 Sep 11.
974 Higher Levels of ANGPTL5 in the Circulation of Subjects With Obesity and Type 2 Diabetes Are Associated With Insulin Resistance.Front Endocrinol (Lausanne). 2019 Jul 24;10:495. doi: 10.3389/fendo.2019.00495. eCollection 2019.
975 Intron retention as an alternative splice variant of the cattle ANGPTL6 gene.Gene. 2019 Aug 15;709:17-24. doi: 10.1016/j.gene.2019.05.031. Epub 2019 May 15.
976 Protein hydrolysate from potato confers hepatic-protection in hamsters against high fat diet induced apoptosis and fibrosis by suppressing Caspase-3 and MMP2/9 and by enhancing Akt-survival pathway.BMC Complement Altern Med. 2019 Oct 25;19(1):283. doi: 10.1186/s12906-019-2700-8.
977 Identification of a novel ARL13B variant in a Joubert syndrome-affected patient with retinal impairment and obesity. Eur J Hum Genet. 2015 May;23(5):621-7. doi: 10.1038/ejhg.2014.156. Epub 2014 Aug 20.
978 A Proteomics-Based Approach Reveals Differential Regulation of Urine Proteins between Metabolically Healthy and Unhealthy Obese Patients.Int J Mol Sci. 2019 Oct 3;20(19):4905. doi: 10.3390/ijms20194905.
979 The risk of overweight and obesity in children with autism spectrum disorders: A systematic review and meta-analysis.Obes Rev. 2019 Dec;20(12):1667-1679. doi: 10.1111/obr.12933. Epub 2019 Oct 8.
980 Myeloid ATG16L1 does not affect adipose tissue inflammation or body mass in mice fed high fat diet.Obes Res Clin Pract. 2018 Mar-Apr;12(2):174-186. doi: 10.1016/j.orcp.2017.10.006. Epub 2017 Nov 2.
981 Platelet Functions are Decreased in Obesity and Restored after Weight Loss: Evidence for a Role of the SERCA3-Dependent ADP Secretion Pathway.Thromb Haemost. 2019 Mar;119(3):384-396. doi: 10.1055/s-0038-1677033. Epub 2019 Jan 16.
982 Downregulation of 1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation.Cell Death Dis. 2018 Feb 7;9(2):196. doi: 10.1038/s41419-017-0239-5.
983 Effect of dietary energy and polymorphisms in BRAP and GHRL on obesity and metabolic traits.Obes Res Clin Pract. 2018 Jan-Feb;12(Suppl 2):39-48. doi: 10.1016/j.orcp.2016.05.004. Epub 2016 May 27.
984 Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients.Diagnostics (Basel). 2019 Jun 21;9(2):63. doi: 10.3390/diagnostics9020063.
985 Detecting epistasis within chromatin regulatory circuitry reveals CAND2 as a novel susceptibility gene for obesity.Int J Obes (Lond). 2019 Mar;43(3):450-456. doi: 10.1038/s41366-018-0069-2. Epub 2018 May 1.
986 Cytokine, Chemokine, and Cytokine Receptor Changes Are Associated With Metabolic Improvements After Bariatric Surgery.J Clin Endocrinol Metab. 2019 Mar 1;104(3):947-956. doi: 10.1210/jc.2018-02245.
987 CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.Cell. 2019 May 30;177(6):1536-1552.e23. doi: 10.1016/j.cell.2019.05.008.
988 CILP-2 is a novel secreted protein and associated with insulin resistance.J Mol Cell Biol. 2019 Dec 19;11(12):1083-1094. doi: 10.1093/jmcb/mjz016.
989 Psychosocial and Cardiometabolic Health of Patients With Differing Body Mass Index Completing Cardiac Rehabilitation.Can J Cardiol. 2019 Jun;35(6):712-720. doi: 10.1016/j.cjca.2019.02.024. Epub 2019 Mar 6.
990 CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity.Mol Metab. 2019 Jan;19:75-85. doi: 10.1016/j.molmet.2018.10.010. Epub 2018 Nov 2.
991 Association of CREBRF variants with obesity and diabetes in Pacific Islanders from Guam and Saipan.Diabetologia. 2019 Sep;62(9):1647-1652. doi: 10.1007/s00125-019-4932-z. Epub 2019 Jul 6.
992 Increased levels of the megakaryocyte and platelet expressed cysteine proteases stefin A and cystatin A prevent thrombosis.Sci Rep. 2019 Jul 3;9(1):9631. doi: 10.1038/s41598-019-45805-9.
993 Metabolic and muscular factors limiting aerobic exercise in obese subjects.Eur J Appl Physiol. 2019 Aug;119(8):1779-1788. doi: 10.1007/s00421-019-04167-w. Epub 2019 Jun 11.
994 CXCL14 Inhibits Insulin Secretion Independently of CXCR4 or CXCR7 Receptor Activation or cAMP Inhibition.Cell Physiol Biochem. 2019;52(4):879-892. doi: 10.33594/000000061.
995 A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice.Int J Mol Sci. 2019 May 13;20(9):2359. doi: 10.3390/ijms20092359.
996 Identification of a rhodanine derivative BML-260 as a potent stimulator of UCP1 expression.Theranostics. 2019 May 26;9(12):3501-3514. doi: 10.7150/thno.31951. eCollection 2019.
997 Circulating Serum Myonectin Levels in Obesity and Type 2 Diabetes Mellitus.Exp Clin Endocrinol Diabetes. 2021 Jul;129(7):528-534. doi: 10.1055/a-0896-8548. Epub 2019 Jul 24.
998 Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI.Transl Psychiatry. 2019 Nov 21;9(1):315. doi: 10.1038/s41398-019-0652-x.
999 Genome-Wide Interaction and Pathway Association Studies for Body Mass Index.Front Genet. 2019 May 1;10:404. doi: 10.3389/fgene.2019.00404. eCollection 2019.
1000 Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity.Int J Obes (Lond). 2019 Jun;43(6):1269-1280. doi: 10.1038/s41366-018-0222-y. Epub 2018 Oct 9.
1001 Overweight in the Elderly Induces a Switch in Energy Metabolism that Undermines Muscle Integrity.Aging Dis. 2019 Apr 1;10(2):217-230. doi: 10.14336/AD.2018.0430. eCollection 2019 Apr.
1002 Expression of apolipoprotein M and its association with adiponectin in an obese mouse model.Exp Ther Med. 2019 Sep;18(3):1685-1692. doi: 10.3892/etm.2019.7755. Epub 2019 Jul 9.
1003 Association of SNP rs7181866 in the nuclear respiratory factor-2 beta subunit encoding GABPB1 gene with obesity and type-2 diabetes mellitus in South Indian population.Int J Biol Macromol. 2019 Jul 1;132:606-614. doi: 10.1016/j.ijbiomac.2019.03.125. Epub 2019 Mar 20.
1004 Poor diet quality in pregnancy is associated with increased risk of excess fetal growth: a prospective multi-racial/ethnic cohort study.Int J Epidemiol. 2019 Apr 1;48(2):423-432. doi: 10.1093/ije/dyy285.
1005 Metabolic Syndrome is Associated with Ceramide Accumulation in Visceral Adipose Tissue of Women with Morbid Obesity.Obesity (Silver Spring). 2019 Mar;27(3):444-453. doi: 10.1002/oby.22405. Epub 2019 Feb 5.
1006 Prepregnancy Obesity, Maternal Dietary Intake, and Oxidative Stress Biomarkers in the Fetomaternal Unit.Biomed Res Int. 2019 Jun 13;2019:5070453. doi: 10.1155/2019/5070453. eCollection 2019.
1007 Inhibitor of Differentiation-3 and Estrogenic Endocrine Disruptors: Implications for Susceptibility to Obesity and Metabolic Disorders.Biomed Res Int. 2018 Jan 8;2018:6821601. doi: 10.1155/2018/6821601. eCollection 2018.
1008 Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation.J Biol Chem. 2019 Aug 2;294(31):11944-11951. doi: 10.1074/jbc.RA119.008778. Epub 2019 Jun 17.
1009 Insulin-like peptide 5 fails to improve metabolism or body weight in obese mice.Peptides. 2019 Oct;120:170116. doi: 10.1016/j.peptides.2019.170116. Epub 2019 Jul 23.
1010 Kbtbd11 gene expression in adipose tissue increases in response to feeding and affects adipocyte differentiation.J Diabetes Investig. 2019 Jul;10(4):925-932. doi: 10.1111/jdi.12995. Epub 2019 Jan 25.
1011 The association of obesity and coronary artery disease genes with response to SSRIs treatment in major depression.J Neural Transm (Vienna). 2019 Jan;126(1):35-45. doi: 10.1007/s00702-018-01966-x. Epub 2019 Jan 4.
1012 KCTD: A new gene family involved in neurodevelopmental and neuropsychiatric disorders.CNS Neurosci Ther. 2019 Jul;25(7):887-902. doi: 10.1111/cns.13156.
1013 Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.Nat Genet. 2018 Jan;50(1):26-41. doi: 10.1038/s41588-017-0011-x. Epub 2017 Dec 22.
1014 Increased Triacylglycerol Lipase Activity in Adipose Tissue of Lean and Obese Men During Endurance Exercise.J Clin Endocrinol Metab. 2017 Nov 1;102(11):3945-3952. doi: 10.1210/jc.2017-00168.
1015 Structure and Mechanism of the Divalent Anion/Na?Symporter.Int J Mol Sci. 2019 Jan 21;20(2):440. doi: 10.3390/ijms20020440.
1016 Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis.Mol Metab. 2019 Jan;19:97-106. doi: 10.1016/j.molmet.2018.10.007. Epub 2018 Oct 23.
1017 Bifidobacteria and its rice fermented products on diet induced obese mice: analysis of physical status, serum profile and gene expressions.Benef Microbes. 2018 Apr 25;9(3):441-452. doi: 10.3920/BM2017.0056. Epub 2018 Feb 7.
1018 The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs.Sci Transl Med. 2019 Jun 12;11(496):eaav1892. doi: 10.1126/scitranslmed.aav1892.
1019 Molecular Characterization of Microtubule Affinity-Regulating Kinase4 from Sus scrofa and Promotion of Lipogenesis in Primary Porcine Placental Trophoblasts.Int J Mol Sci. 2019 Mar 9;20(5):1206. doi: 10.3390/ijms20051206.
1020 Nonalcoholic Fatty Liver Disease (NAFLD), But not Its Susceptibility Gene Variants, Influences the Decrease of Kidney Function in Overweight/Obese Children.Int J Mol Sci. 2019 Sep 9;20(18):4444. doi: 10.3390/ijms20184444.
1021 Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis.EMBO Rep. 2017 Jul;18(7):1123-1138. doi: 10.15252/embr.201643827. Epub 2017 May 24.
1022 Increased Alkaline Phosphatase in Cord Blood of Obese Diabetic Mothers Is Associated to Polyunstaurated Fatty Acid Levels.Ann Nutr Metab. 2019;75(3):153-162. doi: 10.1159/000504404. Epub 2019 Nov 13.
1023 Effects of the estrous cycle and ovarian hormones on cue-triggered motivation and intrinsic excitability of medium spiny neurons in the Nucleus Accumbens core of female rats.Horm Behav. 2019 Nov;116:104583. doi: 10.1016/j.yhbeh.2019.104583. Epub 2019 Sep 10.
1024 Mss51 deletion enhances muscle metabolism and glucose homeostasis in mice.JCI Insight. 2019 Oct 17;4(20):e122247. doi: 10.1172/jci.insight.122247.
1025 Naa10p Inhibits Beige Adipocyte-Mediated Thermogenesis through N--acetylation of Pgc1.Mol Cell. 2019 Nov 7;76(3):500-515.e8. doi: 10.1016/j.molcel.2019.07.026. Epub 2019 Aug 15.
1026 Association of breastfeeding and early exposure to sugar-sweetened beverages with obesity prevalence in offspring born to mothers with and without gestational diabetes mellitus.Pediatr Obes. 2019 Dec;14(12):e12569. doi: 10.1111/ijpo.12569. Epub 2019 Aug 6.
1027 Bariatric Surgery Reduces Elevated Urinary Mitochondrial DNA Copy Number in Patients With Obesity.J Clin Endocrinol Metab. 2019 Jun 1;104(6):2257-2266. doi: 10.1210/jc.2018-01935.
1028 TonEBP/NFAT5 promotes obesity and insulin resistance by epigenetic suppression of white adipose tissue beiging.Nat Commun. 2019 Aug 6;10(1):3536. doi: 10.1038/s41467-019-11302-w.
1029 Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4.Oncogene. 2019 Mar;38(13):2351-2363. doi: 10.1038/s41388-018-0592-6. Epub 2018 Dec 5.
1030 Effects of MC4R, FTO, and NMB gene variants to obesity, physical activity, and eating behavior phenotypes.IUBMB Life. 2016 Oct;68(10):806-16. doi: 10.1002/iub.1558. Epub 2016 Sep 15.
1031 Neuromedin B receptor disruption impairs adipogenesis in mice and 3T3-L1 cells.J Mol Endocrinol. 2019 Jul;63(1):93-102. doi: 10.1530/JME-19-0032.
1032 PEGylated neuromedin U-8 shows long-lasting anorectic activity and anti-obesity effect in mice by peripheral administration.Peptides. 2017 Aug;94:99-105. doi: 10.1016/j.peptides.2017.04.001. Epub 2017 Apr 8.
1033 Pancreastatin inhibitor PSTi8 attenuates hyperinsulinemia induced obesity and inflammation mediated insulin resistance via MAPK/NOX3-JNK pathway.Eur J Pharmacol. 2019 Dec 1;864:172723. doi: 10.1016/j.ejphar.2019.172723. Epub 2019 Oct 3.
1034 Haptoglobin phenotypes with weak antioxidant capacity increase risk factors of cardiovascular disease in Ghanaian HIV-infected patients on highly active antiretroviral therapy.Trop Med Int Health. 2019 Jun;24(6):766-774. doi: 10.1111/tmi.13229. Epub 2019 Mar 21.
1035 PDIA1/P4HB is required for efficient proinsulin maturation and cell health in response to diet induced obesity.Elife. 2019 Jun 11;8:e44528. doi: 10.7554/eLife.44528.
1036 Perm1 regulates CaMKII activation and shapes skeletal muscle responses to endurance exercise training.Mol Metab. 2019 May;23:88-97. doi: 10.1016/j.molmet.2019.02.009. Epub 2019 Feb 27.
1037 The association between obesity and race among Brazilian adults is dependent on sex and socio-economic status.Public Health Nutr. 2018 Aug;21(11):2096-2102. doi: 10.1017/S1368980018000307. Epub 2018 Mar 4.
1038 Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance.Front Endocrinol (Lausanne). 2019 Jun 13;10:373. doi: 10.3389/fendo.2019.00373. eCollection 2019.
1039 Genetic architecture of human thinness compared to severe obesity.PLoS Genet. 2019 Jan 24;15(1):e1007603. doi: 10.1371/journal.pgen.1007603. eCollection 2019 Jan.
1040 Two-week administration of engineered Escherichia coli establishes persistent resistance to diet-induced obesity even without antibiotic pre-treatment.Appl Microbiol Biotechnol. 2019 Aug;103(16):6711-6723. doi: 10.1007/s00253-019-09958-x. Epub 2019 Jun 15.
1041 Inhibition of miR-324-5p increases PM20D1-mediated white and brown adipose loss and reduces body weight in juvenile mice.Eur J Pharmacol. 2019 Nov 15;863:172708. doi: 10.1016/j.ejphar.2019.172708. Epub 2019 Sep 27.
1042 CPI-17-mediated contraction of vascular smooth muscle is essential for the development of hypertension in obese mice.J Genet Genomics. 2019 Mar 20;46(3):109-118. doi: 10.1016/j.jgg.2019.02.005. Epub 2019 Mar 15.
1043 Distribution of local ancestry and evidence of adaptation in admixed populations.Sci Rep. 2019 Sep 25;9(1):13900. doi: 10.1038/s41598-019-50362-2.
1044 Obesity-induced type 2 diabetes impairs neurological recovery after stroke in correlation with decreased neurogenesis and persistent atrophy of parvalbumin-positive interneurons.Clin Sci (Lond). 2019 Jul 1;133(13):1367-1386. doi: 10.1042/CS20190180. Print 2019 Jul 15.
1045 FAM134B improves preadipocytes differentiation by enhancing mitophagy.Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Dec;1864(12):158508. doi: 10.1016/j.bbalip.2019.08.004. Epub 2019 Aug 22.
1046 The Rho GTPase RND3 regulates adipocyte lipolysis.Metabolism. 2019 Dec;101:153999. doi: 10.1016/j.metabol.2019.153999. Epub 2019 Oct 28.
1047 Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women.Metabolism. 2018 Jun;83:81-91. doi: 10.1016/j.metabol.2018.01.014. Epub 2018 Feb 2.
1048 S100A16-induced adipogenesis is associated with up-regulation of 11 -hydroxysteroid dehydrogenase type 1 (11-HSD1).Biosci Rep. 2019 Sep 9;39(9):BSR20182042. doi: 10.1042/BSR20182042. Print 2019 Sep 30.
1049 Early Life Displacement Due to Armed Conflict and Violence, Early Nutrition, and Older Adult Hypertension, Diabetes, and Obesity in the Middle-Income Country of Colombia.J Aging Health. 2019 Sep;31(8):1479-1502. doi: 10.1177/0898264318778111. Epub 2018 Jun 19.
1050 Morbid obesity-related changes in the expression of lipid receptors, transporters, and HSL in human sperm.J Assist Reprod Genet. 2019 Apr;36(4):777-786. doi: 10.1007/s10815-019-01406-z. Epub 2019 Jan 18.
1051 Maternal pre-pregnancy body mass index, smoking in pregnancy, and alcohol intake in pregnancy in relation to pubertal timing in the children.BMC Pediatr. 2019 Sep 16;19(1):338. doi: 10.1186/s12887-019-1715-0.
1052 Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.J Clin Invest. 2018 Mar 1;128(3):1125-1140. doi: 10.1172/JCI96420. Epub 2018 Feb 19.
1053 Selenoprotein W deficiency does not affect oxidative stress and insulin sensitivity in the skeletal muscle of high-fat diet-fed obese mice.Am J Physiol Cell Physiol. 2019 Dec 1;317(6):C1172-C1182. doi: 10.1152/ajpcell.00064.2019. Epub 2019 Sep 11.
1054 Elafibranor Inhibits Chronic Kidney Disease Progression in NASH Mice.Biomed Res Int. 2019 Jun 19;2019:6740616. doi: 10.1155/2019/6740616. eCollection 2019.
1055 Association between Transcription Factor AP-2B genotype, obesity, insulin resistance and dietary intake in a longitudinal birth cohort study.Int J Obes (Lond). 2019 Oct;43(10):2095-2106. doi: 10.1038/s41366-019-0396-y. Epub 2019 Jun 17.
1056 Mouse trefoil factor 3 ameliorated high-fat-diet-induced hepatic steatosis via increasing peroxisome proliferator-activated receptor--mediated fatty acid oxidation.Am J Physiol Endocrinol Metab. 2019 Sep 1;317(3):E436-E445. doi: 10.1152/ajpendo.00454.2018. Epub 2019 Jun 18.
1057 The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing.Cell Rep. 2019 Oct 8;29(2):283-300.e8. doi: 10.1016/j.celrep.2019.08.100.
1058 The genetic association between alpha-2-macroglobulin (A2M) gene deletion polymorphism and low serum A2M concentration in overweight/obese Thais.Nutr Neurosci. 2006 Feb-Apr;9(1-2):93-8. doi: 10.1080/10284150600771777.
1059 2-Aminoadipic acid (2-AAA) as a potential biomarker for insulin resistance in childhood obesity.Sci Rep. 2019 Sep 20;9(1):13610. doi: 10.1038/s41598-019-49578-z.
1060 Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance.Cell Rep. 2018 May 15;23(7):1948-1961. doi: 10.1016/j.celrep.2018.04.055.
1061 Macrophage CGI-58 deficiency promotes IL-1 transcription by activating the SOCS3-FOXO1 pathway.Clin Sci (Lond). 2015 Apr;128(8):493-506. doi: 10.1042/CS20140414.
1062 Elevated Venous Thromboembolism Risk Following Colectomy for IBD Is Equal to Those for Colorectal Cancer for Ninety Days After Surgery.Dis Colon Rectum. 2018 Mar;61(3):375-381. doi: 10.1097/DCR.0000000000001036.
1063 The interaction between aggrecan gene VNTR polymorphism and obesity in predicting incident symptomatic lumbar disc herniation.Connect Tissue Res. 2014 Oct-Dec;55(5-6):384-90. doi: 10.3109/03008207.2014.959117. Epub 2014 Sep 22.
1064 Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2.Cell Oncol (Dordr). 2017 Dec;40(6):537-547. doi: 10.1007/s13402-017-0342-8. Epub 2017 Aug 2.
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1066 Acyl-CoA synthetase long-chain 5 genotype is associated with body composition changes in response to lifestyle interventions in postmenopausal women with overweight and obesity: a genetic association study on cohorts Montral-Ottawa New Emerging Team, and Complications Associated with Obesity.BMC Med Genet. 2016 Aug 11;17(1):56. doi: 10.1186/s12881-016-0320-4.
1067 Left ventricular structure in relation to the human SAH gene in the European Project on Genes in Hypertension.Hypertens Res. 2009 Feb;32(2):145-51. doi: 10.1038/hr.2008.30. Epub 2009 Jan 16.
1068 Adenosine deaminase and body mass index in non-insulin-dependent diabetes mellitus.Metabolism. 1999 Aug;48(8):949-51. doi: 10.1016/s0026-0495(99)90187-7.
1069 ADAM19: A Novel Target for Metabolic Syndrome in Humans and Mice.Mediators Inflamm. 2017;2017:7281986. doi: 10.1155/2017/7281986. Epub 2017 Feb 7.
1070 The Metalloproteinase ADAM28 Promotes Metabolic Dysfunction in Mice.Int J Mol Sci. 2017 Apr 21;18(4):884. doi: 10.3390/ijms18040884.
1071 Association between serum magnesium and blood count: influence of type 2 diabetes and central obesity.Br J Nutr. 2019 Jun;121(11):1287-1293. doi: 10.1017/S0007114519000862. Epub 2019 Apr 29.
1072 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.Nat Genet. 2013 May;45(5):501-12. doi: 10.1038/ng.2606. Epub 2013 Apr 7.
1073 Associations between genetic obesity susceptibility and early postnatal fat and lean mass: an individual participant meta-analysis.JAMA Pediatr. 2014 Dec;168(12):1122-30. doi: 10.1001/jamapediatrics.2014.1619.
1074 Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta.Clin Epigenetics. 2019 Feb 7;11(1):20. doi: 10.1186/s13148-019-0612-6.
1075 Association of copy number variation in the AHI1 gene with risk of obesity in the Chinese population.Eur J Endocrinol. 2012 Apr;166(4):727-34. doi: 10.1530/EJE-11-0999. Epub 2012 Jan 27.
1076 Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight.Epigenetics. 2015;10(10):913-21. doi: 10.1080/15592294.2015.1078963. Epub 2015 Aug 7.
1077 AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.Cell Metab. 2018 Apr 3;27(4):843-853.e6. doi: 10.1016/j.cmet.2018.02.021.
1078 A combination of Lactobacillus mali APS1 and dieting improved the efficacy of obesity treatment via manipulating gut microbiome in mice.Sci Rep. 2018 Apr 18;8(1):6153. doi: 10.1038/s41598-018-23844-y.
1079 Mice deficient in AKAP13 (BRX) develop compulsive-like behavior and increased body weight.Brain Res Bull. 2018 Jun;140:72-79. doi: 10.1016/j.brainresbull.2018.04.005. Epub 2018 Apr 10.
1080 ALMS1 and Alstrm syndrome: a recessive form of metabolic, neurosensory and cardiac deficits.J Mol Med (Berl). 2019 Jan;97(1):1-17. doi: 10.1007/s00109-018-1714-x. Epub 2018 Nov 12.
1081 Hepatocyte ALOXE3 is induced during adaptive fasting and enhances insulin sensitivity by activating hepatic PPAR.JCI Insight. 2018 Aug 23;3(16):e120794. doi: 10.1172/jci.insight.120794. eCollection 2018 Aug 23.
1082 A genome-wide association meta-analysis identifies new childhood obesity loci.Nat Genet. 2012 May;44(5):526-31. doi: 10.1038/ng.2247.
1083 Do Patients with Pre-Existing Psychiatric Illness Have an Increased Risk of Infection after Injury?.Surg Infect (Larchmt). 2017 Jul;18(5):545-549. doi: 10.1089/sur.2016.218. Epub 2017 Mar 29.
1084 Distinctive Reproductive Phenotypes in Peripubertal Girls at Risk for Polycystic Ovary Syndrome.J Clin Endocrinol Metab. 2019 Aug 1;104(8):3355-3361. doi: 10.1210/jc.2018-02313.
1085 AMPD1 gene mutations are associated with obesity and diabetes in Polish patients with cardiovascular diseases.J Appl Genet. 2011 Feb;52(1):67-76. doi: 10.1007/s13353-010-0009-x. Epub 2010 Nov 25.
1086 Knockdown of angiopoietin-like 2 mimics the benefits of intermittent fasting on insulin responsiveness and weight loss.Exp Biol Med (Maywood). 2018 Jan;243(1):45-49. doi: 10.1177/1535370217745505. Epub 2017 Dec 1.
1087 Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):12743-12748. doi: 10.1073/pnas.1708865114. Epub 2017 Nov 13.
1088 Morphological and biochemical features of obesity are associated with mineralization genes' polymorphisms.Int J Obes (Lond). 2010 Aug;34(8):1308-18. doi: 10.1038/ijo.2010.53. Epub 2010 Mar 16.
1089 Complete sequence of the ANKK1 gene in Mexican-Mestizo individuals with obesity, with or without binge eating disorder.Eur Psychiatry. 2018 Oct;54:59-64. doi: 10.1016/j.eurpsy.2018.07.010. Epub 2018 Aug 16.
1090 Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity.Clin Epigenetics. 2019 Dec 4;11(1):181. doi: 10.1186/s13148-019-0768-0.
1091 Annexin A6 is highly abundant in monocytes of obese and type 2 diabetic individuals and is downregulated by adiponectin in vitro.Exp Mol Med. 2009 Jul 31;41(7):501-7. doi: 10.3858/emm.2009.41.7.055.
1092 Physical Interactions and Expression Quantitative Traits Loci Identify Regulatory Connections for Obesity and Type 2 Diabetes Associated SNPs.Front Genet. 2017 Oct 13;8:150. doi: 10.3389/fgene.2017.00150. eCollection 2017.
1093 Preadipocyte stimulating factor in rat serum: evidence for a discrete 63 kDa protein that promotes cell differentiation of rat preadipocytes in primary cultures.J Cell Physiol. 1989 Dec;141(3):543-57. doi: 10.1002/jcp.1041410313.
1094 New Insights into Apolipoprotein A5 and the Modulation of Human Adipose-derived Mesenchymal Stem Cells Adipogenesis.Curr Mol Med. 2020;20(2):144-156. doi: 10.2174/1566524019666190927155702.
1095 High ApoD protein level in the round ligament fat depot of severely obese women is associated with an improved inflammatory profile.Endocrine. 2018 Aug;61(2):248-257. doi: 10.1007/s12020-018-1621-5. Epub 2018 Jun 4.
1096 Apolipoprotein M: new connections with diet, adipose tissue and metabolic syndrome.Curr Opin Lipidol. 2020 Feb;31(1):8-14. doi: 10.1097/MOL.0000000000000654.
1097 Apolipoprotein O is mitochondrial and promotes lipotoxicity in heart.J Clin Invest. 2014 May;124(5):2277-86. doi: 10.1172/JCI74668. Epub 2014 Apr 17.
1098 Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma.Cancer Cell. 2017 Jul 10;32(1):57-70.e3. doi: 10.1016/j.ccell.2017.05.009. Epub 2017 Jun 22.
1099 GTRAP3-18 regulates food intake and body weight by interacting with pro-opiomelanocortin.FASEB J. 2018 Jan;32(1):330-341. doi: 10.1096/fj.201700421R. Epub 2017 Sep 13.
1100 A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis.Dis Model Mech. 2018 Dec 18;11(12):dmm035451. doi: 10.1242/dmm.035451.
1101 Obesity following ART initiation is common and influenced by both traditional and HIV-/ART-specific risk factors.J Antimicrob Chemother. 2018 Aug 1;73(8):2177-2185. doi: 10.1093/jac/dky145.
1102 Effects of Providing High-Fat versus High-Carbohydrate Meals on Daily and Postprandial Physical Activity and Glucose Patterns: a Randomised Controlled Trial.Nutrients. 2018 Apr 30;10(5):557. doi: 10.3390/nu10050557.
1103 Developmental programming of appetite/satiety.Ann Nutr Metab. 2014;64 Suppl 1:36-44. doi: 10.1159/000360508. Epub 2014 Jul 23.
1104 Obesity challenges the hepatoprotective function of the integrated stress response to asparaginase exposure in mice.J Biol Chem. 2017 Apr 21;292(16):6786-6798. doi: 10.1074/jbc.M116.768408. Epub 2017 Feb 27.
1105 The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.EMBO Mol Med. 2018 Mar;10(3):e8047. doi: 10.15252/emmm.201708047.
1106 Huoxue Qianyang decoction ameliorates cardiac remodeling in obese spontaneously hypertensive rats in association with ATF6-CHOP endoplasmic reticulum stress signaling pathway regulation.Biomed Pharmacother. 2020 Jan;121:109518. doi: 10.1016/j.biopha.2019.109518. Epub 2019 Nov 2.
1107 Lipidomic and metabolic changes in the P4-type ATPase ATP10D deficient C57BL/6J wild type mice upon rescue of ATP10D function.PLoS One. 2017 May 25;12(5):e0178368. doi: 10.1371/journal.pone.0178368. eCollection 2017.
1108 Orosomucoid expression profiles in liver, adipose tissues and serum of lean and obese domestic pigs, Gttingen minipigs and Ossabaw minipigs.Vet Immunol Immunopathol. 2013 Feb 15;151(3-4):325-30. doi: 10.1016/j.vetimm.2012.11.002. Epub 2012 Nov 27.
1109 Mitochondrial ATP synthase -subunit production rate and ATP synthase specific activity are reduced in skeletal muscle of humans with obesity.Exp Physiol. 2019 Jan;104(1):126-135. doi: 10.1113/EP087278. Epub 2018 Nov 12.
1110 Tall stature and progressive overweight in mitochondrial encephalopathy.J Inherit Metab Dis. 2003;26(7):720-2. doi: 10.1023/b:boli.0000005647.71704.25.
1111 Mitochondrial DNA variants in obesity.PLoS One. 2014 May 2;9(5):e94882. doi: 10.1371/journal.pone.0094882. eCollection 2014.
1112 The (pro)renin receptor in health and disease.Nat Rev Nephrol. 2019 Nov;15(11):693-712. doi: 10.1038/s41581-019-0160-5.
1113 Attractin: cautionary tales for therapeutic intervention in molecules with pleiotropic functionality.J Environ Pathol Toxicol Oncol. 2004;23(1):1-11. doi: 10.1615/jenvpathtoxoncol.v23.i1.10.
1114 Investigation of common and rare genetic variation in the BAMBI genomic region in light of human obesity.Endocrine. 2016 May;52(2):277-86. doi: 10.1007/s12020-015-0778-4. Epub 2015 Oct 26.
1115 Next-generation sequence analysis of genes associated with obesity and nonalcoholic fatty liver disease-related cirrhosis in extreme obesity.Hum Hered. 2013;75(2-4):144-51. doi: 10.1159/000351719. Epub 2013 Sep 27.
1116 A novel test for recessive contributions to complex diseases implicates Bardet-Biedl syndrome gene BBS10 in idiopathic type 2 diabetes and obesity.Am J Hum Genet. 2014 Nov 6;95(5):509-20. doi: 10.1016/j.ajhg.2014.09.015. Epub 2014 Oct 16.
1117 Bardet-Biedl syndrome gene variants are associated with both childhood and adult common obesity in French Caucasians.Diabetes. 2006 Oct;55(10):2876-82. doi: 10.2337/db06-0337.
1118 Bardet-Biedl syndrome obesity: BBS4 regulates cellular ER stress in early adipogenesis.Mol Genet Metab. 2019 Apr;126(4):495-503. doi: 10.1016/j.ymgme.2019.03.006. Epub 2019 Mar 15.
1119 Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report.BMC Med Genet. 2019 Sep 5;20(1):152. doi: 10.1186/s12881-019-0886-8.
1120 Hepatocyte-specific deletion of BAP31 promotes SREBP1C activation, promotes hepatic lipid accumulation, and worsens IR in mice.J Lipid Res. 2018 Jan;59(1):35-47. doi: 10.1194/jlr.M077016. Epub 2017 Nov 7.
1121 Sweet Killing in Obesity and Diabetes: The Metabolic Role of the BH3-only Protein BIM.J Mol Biol. 2018 Sep 14;430(18 Pt B):3041-3050. doi: 10.1016/j.jmb.2018.07.022. Epub 2018 Jul 21.
1122 Laminar inflammatory events in lean and obese ponies subjected to high carbohydrate feeding: Implications for pasture-associated laminitis.Equine Vet J. 2015 Jul;47(4):489-93. doi: 10.1111/evj.12314. Epub 2014 Sep 10.
1123 Deficiency of the basic helix-loop-helix transcription factor DEC1 prevents obesity induced by a high-fat diet in mice.Genes Cells. 2018 Jul 3. doi: 10.1111/gtc.12607. Online ahead of print.
1124 Are genetic variants of the methyl group metabolism enzymes risk factors predisposing to obesity?.J Endocrinol Invest. 2007 Oct;30(9):747-53. doi: 10.1007/BF03350812.
1125 Coadministration of lorcaserin and phentermine for weight management: A 12-week, randomized, pilot safety study.Obesity (Silver Spring). 2017 May;25(5):857-865. doi: 10.1002/oby.21811.
1126 Reestablishment of Energy Balance in a Male Mouse Model With POMC Neuron Deletion of BMPR1A.Endocrinology. 2017 Dec 1;158(12):4233-4245. doi: 10.1210/en.2017-00212.
1127 Null variants and deletions in BRWD3 cause an X-linked syndrome of mild-moderate intellectual disability, macrocephaly, and obesity: A series of 17 patients.Am J Med Genet C Semin Med Genet. 2019 Dec;181(4):638-643. doi: 10.1002/ajmg.c.31750. Epub 2019 Nov 12.
1128 Visceral obesity stimulates anaphase bridge formation and spindle assembly checkpoint dysregulation in radioresistant oesophageal adenocarcinoma.Clin Transl Oncol. 2016 Jun;18(6):632-40. doi: 10.1007/s12094-015-1411-y. Epub 2015 Oct 16.
1129 Obesity and chronic kidney disease progression-the role of a new adipocytokine: C1q/tumour necrosis factor-related protein-1.Clin Kidney J. 2018 Oct 11;12(3):420-426. doi: 10.1093/ckj/sfy095. eCollection 2019 Jun.
1130 Lower circulating levels of CTRP12 and CTRP13 in polycystic ovarian syndrome: Irrespective of obesity.PLoS One. 2018 Dec 12;13(12):e0208059. doi: 10.1371/journal.pone.0208059. eCollection 2018.
1131 Circulating complement-1q tumor necrosis factor--related protein isoform5 levels are low in type2 diabetes patients and reduced by dapagliflozin.J Diabetes Investig. 2020 Jan;11(1):88-95. doi: 10.1111/jdi.13069. Epub 2019 Jun 6.
1132 CTRP7 deletion attenuates obesity-linked glucose intolerance, adipose tissue inflammation, and hepatic stress.Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E309-E325. doi: 10.1152/ajpendo.00344.2016. Epub 2017 Feb 21.
1133 Serum C1q/TNF-related protein 9 is not related to nonalcoholic fatty liver disease.Cytokine. 2018 Oct;110:52-57. doi: 10.1016/j.cyto.2018.04.019. Epub 2018 Apr 25.
1134 Membrane Trafficking Protein CDP138 Regulates Fat Browning and Insulin Sensitivity through Controlling Catecholamine Release.Mol Cell Biol. 2018 Mar 29;38(8):e00153-17. doi: 10.1128/MCB.00153-17. Print 2018 Apr 15.
1135 Genetic variation in CADM2 as a link between psychological traits and obesity.Sci Rep. 2019 May 14;9(1):7339. doi: 10.1038/s41598-019-43861-9.
1136 Obesity and ischemic stroke modulate the methylation levels of KCNQ1 in white blood cells.Hum Mol Genet. 2015 Mar 1;24(5):1432-40. doi: 10.1093/hmg/ddu559. Epub 2014 Nov 4.
1137 Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism.Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):16064-9. doi: 10.1073/pnas.0405041101. Epub 2004 Nov 1.
1138 The essential function of CARD9 in diet-induced inflammation and metabolic disorders in mice.J Cell Mol Med. 2018 Jun;22(6):2993-3004. doi: 10.1111/jcmm.13494. Epub 2018 Mar 25.
1139 Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index.Mol Psychiatry. 2017 Feb;22(2):192-201. doi: 10.1038/mp.2016.71. Epub 2016 May 17.
1140 Calpain Inhibition Attenuates Adipose Tissue Inflammation and Fibrosis in Diet-induced Obese Mice.Sci Rep. 2017 Oct 31;7(1):14398. doi: 10.1038/s41598-017-14719-9.
1141 Polymerase I and transcript release factor (PTRF) regulates adipocyte differentiation and determines adipose tissue expandability.FASEB J. 2014 Aug;28(8):3769-79. doi: 10.1096/fj.14-251165. Epub 2014 May 8.
1142 Identification of the inhibitory activity of walnut extract on the E3 ligase Syvn1.Mol Med Rep. 2018 Dec;18(6):5701-5708. doi: 10.3892/mmr.2018.9576. Epub 2018 Oct 23.
1143 Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice.J Clin Invest. 2010 Feb;120(2):545-58. doi: 10.1172/JCI39319. Epub 2010 Jan 11.
1144 Loss of DRO1/CCDC80 results in obesity and promotes adipocyte differentiation.Mol Cell Endocrinol. 2017 Jan 5;439:286-296. doi: 10.1016/j.mce.2016.09.014. Epub 2016 Sep 16.
1145 Hypertension in aortic stenosis: relationship with revealed symptoms and functional measures on treadmill exercise.J Hypertens. 2019 Nov;37(11):2209-2215. doi: 10.1097/HJH.0000000000002149.
1146 Adipose and Circulating CCL18 Levels Associate With Metabolic Risk Factors in Women.J Clin Endocrinol Metab. 2016 Nov;101(11):4021-4029. doi: 10.1210/jc.2016-2390. Epub 2016 Jul 26.
1147 Adipose tissue expression of CCL19 chemokine is positively associated with insulin resistance.Diabetes Metab Res Rev. 2019 Feb;35(2):e3087. doi: 10.1002/dmrr.3087. Epub 2018 Nov 8.
1148 Innate lymphoid cells at the interface between obesity and asthma.Immunology. 2018 Jan;153(1):21-30. doi: 10.1111/imm.12832. Epub 2017 Sep 26.
1149 Exercise initiated after the onset of insulin resistance improves trabecular microarchitecture and cortical bone biomechanics of the tibia in hyperphagic Otsuka Long Evans Tokushima Fatty rats.Bone. 2017 Oct;103:188-199. doi: 10.1016/j.bone.2017.07.010. Epub 2017 Jul 12.
1150 Plasma immunological markers in pregnancy and cord blood: Apossible link between macrophage chemo-attractants and risk of childhood type 1 diabetes.Am J Reprod Immunol. 2018 Mar;79(3). doi: 10.1111/aji.12802. Epub 2017 Dec 20.
1151 Expression of monocyte chemotactic protein 3 following simulated birth trauma in a murine model of obesity.Urology. 2010 Dec;76(6):1517.e12-7. doi: 10.1016/j.urology.2010.07.466. Epub 2010 Oct 23.
1152 Monocyte chemoattractant protein-1 in subcutaneous abdominal adipose tissue: characterization of interstitial concentration and regulation of gene expression by insulin.J Clin Endocrinol Metab. 2007 Jul;92(7):2688-95. doi: 10.1210/jc.2006-2814. Epub 2007 Apr 24.
1153 Assessment of circulating Wnt1 inducible signalling pathway protein 1 (WISP-1)/CCN4 as a novel biomarker of obesity.J Cell Commun Signal. 2018 Sep;12(3):539-548. doi: 10.1007/s12079-017-0427-1. Epub 2017 Nov 11.
1154 CCN5/WISP2 and metabolic diseases.J Cell Commun Signal. 2018 Mar;12(1):309-318. doi: 10.1007/s12079-017-0437-z. Epub 2017 Dec 15.
1155 The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation.Diabetes. 2012 May;61(5):1199-209. doi: 10.2337/db11-1182. Epub 2012 Mar 6.
1156 Comparative genome analysis with the human genome reveals chicken genes associated with fatness and body weight.Anim Genet. 2011 Dec;42(6):642-9. doi: 10.1111/j.1365-2052.2011.02191.x. Epub 2011 Apr 13.
1157 Relationship between variants of the leptin gene and obesity and metabolic biomarkers in Brazilian individuals.Arq Bras Endocrinol Metabol. 2010 Mar;54(3):282-8. doi: 10.1590/s0004-27302010000300006.
1158 Putative targets of CNS melanocortin receptor activity.Ann N Y Acad Sci. 2003 Jun;994:211-7. doi: 10.1111/j.1749-6632.2003.tb03182.x.
1159 Influence of obesity, age, and comorbidities on the multi-biomarker disease activity test in rheumatoid arthritis.Semin Arthritis Rheum. 2018 Feb;47(4):472-477. doi: 10.1016/j.semarthrit.2017.07.010. Epub 2017 Aug 2.
1160 CDH13 abundance interferes with adipocyte differentiation and is a novel biomarker for adipose tissue health.Int J Obes (Lond). 2018 Jun;42(5):1039-1050. doi: 10.1038/s41366-018-0022-4. Epub 2018 Feb 21.
1161 Protective Effects of an Obesity-Associated Polymorphism (CDKAL1 rs9356744) on Prediabetes: The Cardiometabolic Risk in Chinese (CRC) Study.Exp Clin Endocrinol Diabetes. 2018 Sep;126(9):540-545. doi: 10.1055/s-0042-109607. Epub 2018 Jun 22.
1162 Artemisinic acid is a regulator of adipocyte differentiation and C/EBP expression.J Cell Biochem. 2012 Jul;113(7):2488-99. doi: 10.1002/jcb.24124.
1163 Haploinsufficiency of CELF4 at 18q12.2 is associated with developmental and behavioral disorders, seizures, eye manifestations, and obesity.Eur J Hum Genet. 2012 Dec;20(12):1315-9. doi: 10.1038/ejhg.2012.92. Epub 2012 May 23.
1164 Sleep-disordered breathing, circulating exosomes, and insulin sensitivity in adipocytes.Int J Obes (Lond). 2018 Jun;42(6):1127-1139. doi: 10.1038/s41366-018-0099-9. Epub 2018 Jun 11.
1165 Gating Ciliary Transport.Dev Cell. 2017 Jul 10;42(1):5-6. doi: 10.1016/j.devcel.2017.06.016.
1166 C21orf2 is mutated in recessive early-onset retinal dystrophy with macular staphyloma and encodes a protein that localises to the photoreceptor primary cilium.Br J Ophthalmol. 2015 Dec;99(12):1725-31. doi: 10.1136/bjophthalmol-2015-307277. Epub 2015 Aug 20.
1167 High molecular weight adiponectin reduces glucolipotoxicity-induced inflammation and improves lipid metabolism and insulin sensitivity via APPL1-AMPK-GLUT4 regulation in 3T3-L1 adipocytes.Atherosclerosis. 2019 Sep;288:67-75. doi: 10.1016/j.atherosclerosis.2019.07.011. Epub 2019 Jul 12.
1168 CGRRF1 as a novel biomarker of tissue response to metformin in the context of obesity.Gynecol Oncol. 2014 Apr;133(1):83-9. doi: 10.1016/j.ygyno.2013.12.006.
1169 A cafeteria diet triggers intestinal inflammation and oxidative stress in obese rats.Br J Nutr. 2017 Jan;117(2):218-229. doi: 10.1017/S0007114516004608. Epub 2017 Jan 30.
1170 A case of 14q11.2 microdeletion with autistic features, severe obesity and facial dysmorphisms suggestive of Wolf-Hirschhorn syndrome.Am J Med Genet A. 2014 Jan;164A(1):190-3. doi: 10.1002/ajmg.a.36200. Epub 2013 Nov 15.
1171 The Differential Expression of Cide Family Members is Associated with Nafld Progression from Steatosis to Steatohepatitis.Sci Rep. 2019 May 16;9(1):7501. doi: 10.1038/s41598-019-43928-7.
1172 FSP27 and Links to Obesity and Diabetes Mellitus.Curr Obes Rep. 2019 Sep;8(3):255-261. doi: 10.1007/s13679-019-00343-3.
1173 CISD1 in association with obesity-associated dysfunctional adipogenesis in human visceral adipose tissue.Obesity (Silver Spring). 2016 Jan;24(1):139-47. doi: 10.1002/oby.21334.
1174 Structure-function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease.Biochim Biophys Acta. 2015 Jun;1853(6):1294-315. doi: 10.1016/j.bbamcr.2014.10.014. Epub 2014 Oct 23.
1175 Insulin Downregulates the Transcriptional Coregulator CITED2, an Inhibitor of Proangiogenic Function in Endothelial Cells.Diabetes. 2016 Dec;65(12):3680-3690. doi: 10.2337/db16-0001. Epub 2016 Aug 25.
1176 Obesity is associated with shorter telomeres in 8 year-old children.Sci Rep. 2019 Dec 10;9(1):18739. doi: 10.1038/s41598-019-55283-8.
1177 Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88.Cell Rep. 2017 Jun 13;19(11):2272-2288. doi: 10.1016/j.celrep.2017.05.059.
1178 Genetic resistance to liver fibrosis on A/J mouse chromosome 17.Alcohol Clin Exp Res. 2013 Oct;37(10):1668-79. doi: 10.1111/acer.12157. Epub 2013 Jun 13.
1179 Opposite Genetic Effects of CMIP Polymorphisms on the Risk of Type 2 Diabetes and Obesity: A Family-Based Study in China.Int J Mol Sci. 2018 Mar 28;19(4):1011. doi: 10.3390/ijms19041011.
1180 Consumption of Ocimum sanctum L. and Citrus paradisi infusions modulates lipid metabolism and insulin resistance in obese rats.Food Funct. 2014 May;5(5):927-35. doi: 10.1039/c3fo60604j.
1181 The Combined Effects of Genetic Variation in the CNDP1 and CNDP2 Genes and Dietary Carbohydrate and Carotene Intake on Obesity Risk.J Nutrigenet Nutrigenomics. 2017;10(5-6):146-154. doi: 10.1159/000485798. Epub 2018 Jan 17.
1182 Obesity-insulin targeted genes in the 3p26-25 region in human studies and LG/J and SM/J mice.Metabolism. 2012 Aug;61(8):1129-41. doi: 10.1016/j.metabol.2012.01.008. Epub 2012 Mar 3.
1183 Unexpected phenotypic effects of a transgene integration causing a knockout of the endogenous Contactin-5 gene in mice.Transgenic Res. 2018 Feb;27(1):1-13. doi: 10.1007/s11248-017-0053-y. Epub 2017 Dec 20.
1184 Alterations in circadian and meal-induced gut peptide levels in lean and obese rats.Exp Biol Med (Maywood). 2017 Dec;242(18):1786-1794. doi: 10.1177/1535370217732041. Epub 2017 Sep 15.
1185 Acute inflammation plays a limited role in the regulation of adipose tissue COL1A1 protein abundance.J Nutr Biochem. 2012 Jun;23(6):567-72. doi: 10.1016/j.jnutbio.2011.02.013. Epub 2011 Jul 19.
1186 Knocking out or pharmaceutical inhibition of fatty acid binding protein 4 (FABP4) alleviates osteoarthritis induced by high-fat diet in mice.Osteoarthritis Cartilage. 2018 Jun;26(6):824-833. doi: 10.1016/j.joca.2018.03.002. Epub 2018 Mar 13.
1187 Emerging therapeutic potential for xenin and related peptides in obesity and diabetes.Diabetes Metab Res Rev. 2018 Sep;34(6):e3006. doi: 10.1002/dmrr.3006. Epub 2018 Apr 26.
1188 Lack of cortistatin or somatostatin differentially influences DMBA-induced mammary gland tumorigenesis in mice in an obesity-dependent mode.Breast Cancer Res. 2016 Mar 8;18(1):29. doi: 10.1186/s13058-016-0689-1.
1189 Low cytochrome oxidase 4I1 links mitochondrial dysfunction to obesity and type 2 diabetes in humans and mice.Int J Obes (Lond). 2015 Aug;39(8):1254-63. doi: 10.1038/ijo.2015.58. Epub 2015 Apr 14.
1190 Prevalence of Obesity in Young Patients with Severe Haemophilia and Its Potential Impact on Factor VIII Consumption in Germany.Hamostaseologie. 2019 Nov;39(4):355-359. doi: 10.1055/s-0039-1677874. Epub 2019 Feb 5.
1191 Genetic variants in the CPNE5 gene are associated with alcohol dependence and obesity in Caucasian populations.J Psychiatr Res. 2015 Dec;71:1-7. doi: 10.1016/j.jpsychires.2015.09.008. Epub 2015 Sep 14.
1192 Cellular retinoic acid binding protein 1 protects mice from high-fat diet-induced obesity by decreasing adipocyte hypertrophy.Int J Obes (Lond). 2020 Feb;44(2):466-474. doi: 10.1038/s41366-019-0379-z. Epub 2019 Jun 4.
1193 CREG1 stimulates brown adipocyte formation and ameliorates diet-induced obesity in mice.FASEB J. 2019 Jul;33(7):8069-8082. doi: 10.1096/fj.201802147RR. Epub 2019 Mar 27.
1194 Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function.Mol Metab. 2016 Oct 5;5(12):1200-1207. doi: 10.1016/j.molmet.2016.09.011. eCollection 2016 Dec.
1195 Interaction of thrombospondin1 and CD36 contributes to obesity-associated podocytopathy.Biochim Biophys Acta. 2015 Jul;1852(7):1323-33. doi: 10.1016/j.bbadis.2015.03.010. Epub 2015 Mar 31.
1196 Regulation role of CRTC3 in skeletal muscle and adipose tissue.J Cell Physiol. 2018 Feb;233(2):818-821. doi: 10.1002/jcp.25917. Epub 2017 May 19.
1197 Lack of CUL4B in Adipocytes Promotes PPAR-Mediated Adipose Tissue Expansion and Insulin Sensitivity.Diabetes. 2017 Feb;66(2):300-313. doi: 10.2337/db16-0743. Epub 2016 Nov 29.
1198 The overweight increases circulating inflammatory mediators commonly associated with obesity in young individuals.Cytokine. 2018 Oct;110:169-173. doi: 10.1016/j.cyto.2018.04.024. Epub 2018 May 12.
1199 Implication of CXCL5 (epithelial neutrophil-activating peptide 78) in the development of insulin resistance in patients with rheumatoid arthritis.Clin Exp Rheumatol. 2019 May-Jun;37(3):373-379. Epub 2018 Sep 17.
1200 Alcohol increases tumor necrosis factor alpha and decreases nuclear factor-kappab to activate hepatic apoptosis in genetically obese mice.Hepatology. 2005 Dec;42(6):1280-90. doi: 10.1002/hep.20949.
1201 Statistical Binning for Barcoded Reads Improves Downstream Analyses.Cell Syst. 2018 Aug 22;7(2):219-226.e5. doi: 10.1016/j.cels.2018.07.005.
1202 Gut microbiota composition correlates with changes in body fat content due to weight loss.Benef Microbes. 2015;6(4):431-9. doi: 10.3920/BM2014.0104. Epub 2015 Feb 12.
1203 The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system.J Clin Invest. 2019 Apr 2;129(6):2417-2430. doi: 10.1172/JCI123454.
1204 Chromosome 17q23: a locus for cardiovascular disease.Clin Exp Pharmacol Physiol. 1993 May;20(5):279-82. doi: 10.1111/j.1440-1681.1993.tb01683.x.
1205 Protective role of DDAH2 (rs805304) gene polymorphism in patients with myocardial infarction.Exp Mol Pathol. 2014 Dec;97(3):393-8. doi: 10.1016/j.yexmp.2014.09.015. Epub 2014 Sep 16.
1206 Late-onset spastic ataxia phenotype in a patient with a homozygous DDHD2 mutation.Sci Rep. 2014 Nov 24;4:7132. doi: 10.1038/srep07132.
1207 The role of DENND1A and CYP19A1 gene variants in individual susceptibility to obesity in Turkish population-a preliminary study.Mol Biol Rep. 2018 Dec;45(6):2193-2199. doi: 10.1007/s11033-018-4380-8. Epub 2018 Sep 19.
1208 Insulin inhibits leptin receptor signalling in HEK293 cells at the level of janus kinase-2: a potential mechanism for hyperinsulinaemia-associated leptin resistance.Diabetologia. 2001 Sep;44(9):1125-32. doi: 10.1007/s001250100614.
1209 Deletion of diacylglycerol kinase confers susceptibility to obesity via reduced lipolytic activity in murine adipocytes.FASEB J. 2018 Aug;32(8):4121-4131. doi: 10.1096/fj.201701050R. Epub 2018 Mar 6.
1210 Risk factors for diabetic macular oedema in type 2 diabetes: A case-control study in a United Kingdom primary care setting.Prim Care Diabetes. 2017 Jun;11(3):288-296. doi: 10.1016/j.pcd.2017.03.002. Epub 2017 Apr 7.
1211 Prolonged Exposure of Primary Human Muscle Cells to Plasma Fatty Acids Associated with Obese Phenotype Induces Persistent Suppression of Muscle Mitochondrial ATP Synthase Subunit.PLoS One. 2016 Aug 17;11(8):e0160057. doi: 10.1371/journal.pone.0160057. eCollection 2016.
1212 DNAJB3/HSP-40 cochaperone is downregulated in obese humans and is restored by physical exercise.PLoS One. 2013 Jul 24;8(7):e69217. doi: 10.1371/journal.pone.0069217. Print 2013.
1213 MDG-1, an Ophiopogon polysaccharide, restrains process of non-alcoholic fatty liver disease via modulating the gut-liver axis.Int J Biol Macromol. 2019 Dec 1;141:1013-1021. doi: 10.1016/j.ijbiomac.2019.09.007. Epub 2019 Sep 3.
1214 Increased Circulation and Adipose Tissue Levels of DNAJC27/RBJ in Obesity and Type 2-Diabetes.Front Endocrinol (Lausanne). 2018 Aug 7;9:423. doi: 10.3389/fendo.2018.00423. eCollection 2018.
1215 DNAJC6 is responsible for juvenile parkinsonism with phenotypic variability.Parkinsonism Relat Disord. 2013 Mar;19(3):320-4. doi: 10.1016/j.parkreldis.2012.11.006. Epub 2012 Dec 2.
1216 DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure.J Lipid Res. 2017 Sep;58(9):1777-1784. doi: 10.1194/jlr.M073049. Epub 2017 Jul 17.
1217 Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity.Hum Mol Genet. 2012 Aug 15;21(16):3727-38. doi: 10.1093/hmg/dds187. Epub 2012 May 16.
1218 Evaluation of DOK5 as a susceptibility gene for type 2 diabetes and obesity in North Indian population.BMC Med Genet. 2010 Feb 27;11:35. doi: 10.1186/1471-2350-11-35.
1219 p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adipocytes and cancer cells.Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8370-8375. doi: 10.1073/pnas.1804243115. Epub 2018 Jul 30.
1220 Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children.Endocr Connect. 2018 Jan;7(1):232-238. doi: 10.1530/EC-17-0344. Epub 2017 Dec 13.
1221 Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice.PLoS One. 2017 Sep 5;12(9):e0183488. doi: 10.1371/journal.pone.0183488. eCollection 2017.
1222 Pleiotropy of cardiometabolic syndrome with obesity-related anthropometric traits determined using empirically derived kinships from the Busselton Health Study.Hum Genet. 2018 Jan;137(1):45-53. doi: 10.1007/s00439-017-1856-x. Epub 2017 Nov 27.
1223 Tissue cell stress response to obesity and its interaction with late gestation diet.Reprod Fertil Dev. 2018 Mar;30(3):430-441. doi: 10.1071/RD16494.
1224 A novel role for adipose ephrin-B1 in inflammatory response.PLoS One. 2013 Oct 1;8(10):e76199. doi: 10.1371/journal.pone.0076199. eCollection 2013.
1225 Dietary Intake of Curcumin Improves eIF2 Signaling and Reduces Lipid Levels in the White Adipose Tissue of Obese Mice.Sci Rep. 2018 Jun 13;8(1):9081. doi: 10.1038/s41598-018-27105-w.
1226 High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4(+) T cells in both mice and humans.Dev Comp Immunol. 2017 Dec;77:69-76. doi: 10.1016/j.dci.2017.07.022. Epub 2017 Jul 22.
1227 Reduction and fragmentation of elastic fibers in the skin of obese mice is associated with altered mRNA expression levels of fibrillin-1 and neprilysin.Connect Tissue Res. 2017 Sep;58(5):479-486. doi: 10.1080/03008207.2016.1255205. Epub 2016 Nov 28.
1228 Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.J Lipid Res. 2014 Jul;55(7):1448-64. doi: 10.1194/jlr.M050062. Epub 2014 May 9.
1229 Elovl6: a new player in fatty acid metabolism and insulin sensitivity.J Mol Med (Berl). 2009 Apr;87(4):379-84. doi: 10.1007/s00109-009-0449-0. Epub 2009 Mar 4.
1230 Metabolic and Cardiovascular Benefits and Risks of EMD386088-A 5-HT(6) Receptor Partial Agonist and Dopamine Transporter Inhibitor.Front Neurosci. 2017 Feb 8;11:50. doi: 10.3389/fnins.2017.00050. eCollection 2017.
1231 Obesity and genetic polymorphism of ERCC2 and ERCC4 as modifiers of risk of breast cancer.Exp Mol Med. 2005 Apr 30;37(2):86-90. doi: 10.1038/emm.2005.12.
1232 Genome-wide screen of DNA methylation identifies novel markers in childhood obesity.Gene. 2015 Jul 15;566(1):74-83. doi: 10.1016/j.gene.2015.04.032. Epub 2015 Apr 12.
1233 Family with sequence similarity 3 gene family and nonalcoholic fatty liver disease.J Gastroenterol Hepatol. 2013 Aug;28 Suppl 1:105-11. doi: 10.1111/jgh.12033.
1234 Targeting Sleep, Food, and Activity in Infants for Obesity Prevention: An RCT.Pediatrics. 2017 Mar;139(3):e20162037. doi: 10.1542/peds.2016-2037.
1235 Central obesity and the Mediterranean diet: A systematic review of intervention trials.Crit Rev Food Sci Nutr. 2018;58(18):3070-3084. doi: 10.1080/10408398.2017.1351917. Epub 2017 Oct 17.
1236 Impact of Obesity and Alanine Aminotransferase Levels on the Diagnostic Accuracy for Advanced Liver Fibrosis of Noninvasive Tools in Patients With Nonalcoholic Fatty Liver Disease.Am J Gastroenterol. 2019 Jun;114(6):916-928. doi: 10.14309/ajg.0000000000000153.
1237 Serum asprosin levels and bariatric surgery outcomes in obese adults.Int J Obes (Lond). 2019 May;43(5):1019-1025. doi: 10.1038/s41366-018-0248-1. Epub 2018 Nov 20.
1238 Prenatal Exposure to Bisphenol A Disrupts Naturally Occurring Bimodal DNA Methylation at Proximal Promoter of fggy, an Obesity-Relevant Gene Encoding a Carbohydrate Kinase, in Gonadal White Adipose Tissues of CD-1 Mice.Endocrinology. 2018 Feb 1;159(2):779-794. doi: 10.1210/en.2017-00711.
1239 Discovery of a role of the novel hepatokine, hepassocin, in obesity.Biofactors. 2020 Jan;46(1):100-105. doi: 10.1002/biof.1574. Epub 2019 Oct 6.
1240 Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.Hum Genet. 2016 Aug;135(8):869-80. doi: 10.1007/s00439-016-1680-8. Epub 2016 May 19.
1241 Obesity caused by a high-fat diet regulates the Sirt1/PGC-1/FNDC5/BDNF pathway to exacerbate isoflurane-induced postoperative cognitive dysfunction in older mice.Nutr Neurosci. 2020 Dec;23(12):971-982. doi: 10.1080/1028415X.2019.1581460. Epub 2019 Feb 22.
1242 Beneficial effects of metformin on muscle atrophy induced by obesity in rats.J Cell Biochem. 2019 Apr;120(4):5677-5686. doi: 10.1002/jcb.27852. Epub 2018 Oct 15.
1243 The role of the FTO (Fat Mass and Obesity Related) locus in regulating body size and composition.Mol Cell Endocrinol. 2014 Nov;397(1-2):34-41. doi: 10.1016/j.mce.2014.09.012. Epub 2014 Sep 16.
1244 Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome.Autophagy. 2019 Nov;15(11):1882-1898. doi: 10.1080/15548627.2019.1596482. Epub 2019 Apr 6.
1245 Uncoupling protein 2 polymorphisms as risk factors for NTDs.Birth Defects Res A Clin Mol Teratol. 2009 Feb;85(2):156-60. doi: 10.1002/bdra.20520.
1246 Regulation of G0/G1 switch gene 2 (G0S2) expression in human adipose tissue.Arch Physiol Biochem. 2016;122(2):47-53. doi: 10.3109/13813455.2015.1122066. Epub 2016 Jan 27.
1247 Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease.J Mol Cell Biol. 2016 Dec;8(6):492-504. doi: 10.1093/jmcb/mjw028. Epub 2016 Jun 9.
1248 Obesity-induced sympathoexcitation is associated with Nrf2 dysfunction in the rostral ventrolateral medulla.Am J Physiol Regul Integr Comp Physiol. 2020 Feb 1;318(2):R435-R444. doi: 10.1152/ajpregu.00206.2019. Epub 2019 Dec 11.
1249 Association between a variant at the GABA(A)alpha6 receptor subunit gene, abdominal obesity, and cortisol secretion.Ann N Y Acad Sci. 2002 Jun;967:566-70. doi: 10.1111/j.1749-6632.2002.tb04318.x.
1250 Regulation of Feeding Behavior and Energy Metabolism by Galanin-like Peptide (GALP): A Novel Strategy to Fight Against Obesity.Curr Pharm Des. 2018;24(33):3926-3933. doi: 10.2174/1381612824666181106111623.
1251 Bioavailable and free 25-hydroxyvitamin D and vitamin D binding protein in polycystic ovary syndrome: Relationships with obesity and insulin resistance.J Steroid Biochem Mol Biol. 2018 Mar;177:209-215. doi: 10.1016/j.jsbmb.2017.07.012. Epub 2017 Jul 19.
1252 Association of FTO polymorphisms with obesity and obesity-related outcomes in Portuguese children.PLoS One. 2013;8(1):e54370. doi: 10.1371/journal.pone.0054370. Epub 2013 Jan 14.
1253 Lipid regulatory genes polymorphism in children with and without obesity and cardiometabolic risk factors: The CASPIAN-III study.J Res Med Sci. 2018 Feb 20;23:11. doi: 10.4103/jrms.JRMS_911_17. eCollection 2018.
1254 Overexpression of bone morphogenetic protein-3b (BMP-3b) in adipose tissues protects against high-fat diet-induced obesity.Int J Obes (Lond). 2017 Apr;41(4):483-488. doi: 10.1038/ijo.2017.15. Epub 2017 Jan 20.
1255 Type 2 diabetes and metabolic syndrome - adipokine levels and effect of drugs.Gynecol Endocrinol. 2017 Jan;33(1):75-78. doi: 10.1080/09513590.2016.1207165. Epub 2016 Oct 5.
1256 Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of Gfi1 expression.J Exp Med. 2018 Feb 5;215(2):627-644. doi: 10.1084/jem.20170690. Epub 2017 Dec 27.
1257 The -1438A/G polymorphism in the 5-hydroxytryptamine receptor 2A gene is related to hyperuricemia, increased gamma-glutamyl transpeptidase and decreased high-density lipoprotein cholesterol level in the Japanese population: a prospective cohort study over 5 years.Int J Mol Med. 2006 Jan;17(1):77-82.
1258 CCAAT-enhancer-binding protein (C/EBP) and downstream human placental growth hormone genes are targets for dysregulation in pregnancies complicated by maternal obesity.J Biol Chem. 2013 Aug 2;288(31):22849-61. doi: 10.1074/jbc.M113.474999. Epub 2013 Jun 19.
1259 Cold exposure promotes obesity and impairs glucose homeostasis in mice subjected to a highfat diet.Mol Med Rep. 2018 Oct;18(4):3923-3931. doi: 10.3892/mmr.2018.9382. Epub 2018 Aug 10.
1260 Implications of Aquaglyceroporin 7 in Energy Metabolism.Int J Mol Sci. 2018 Jan 4;19(1):154. doi: 10.3390/ijms19010154.
1261 Genetic and clinical factors associated with obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort.Cancer. 2015 Jul 1;121(13):2262-70. doi: 10.1002/cncr.29153. Epub 2015 May 11.
1262 G12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration.J Clin Invest. 2018 Dec 3;128(12):5587-5602. doi: 10.1172/JCI97831. Epub 2018 Nov 12.
1263 G13 ablation reprograms myofibers to oxidative phenotype and enhances whole-body metabolism.J Clin Invest. 2017 Oct 2;127(10):3845-3860. doi: 10.1172/JCI92067. Epub 2017 Sep 18.
1264 Gustation genetics: sweet gustducin!.Chem Senses. 2010 Sep;35(7):549-50. doi: 10.1093/chemse/bjq059. Epub 2010 Jul 21.
1265 An evaluation of liraglutide including its efficacy and safety for the treatment of obesity.Expert Opin Pharmacother. 2020 Feb;21(3):275-285. doi: 10.1080/14656566.2019.1695779. Epub 2019 Dec 2.
1266 Greater Curvature Plication with Duodenal-Jejunal Bypass: a Novel Metabolic Surgery for Type 2 Diabetes Mellitus.Obes Surg. 2018 Jun;28(6):1595-1601. doi: 10.1007/s11695-017-3057-z.
1267 Genetic susceptibility, birth weight and obesity risk in young Chinese.Int J Obes (Lond). 2013 May;37(5):673-7. doi: 10.1038/ijo.2012.87. Epub 2012 Jun 19.
1268 Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis.Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19695-700. doi: 10.1073/pnas.0609140103. Epub 2006 Dec 14.
1269 Serum glypican 4 level in obese children and its relation to degree of obesity.Clin Endocrinol (Oxf). 2017 Dec;87(6):689-695. doi: 10.1111/cen.13435. Epub 2017 Aug 22.
1270 The Italian Version of the Inventory of Interpersonal Problems (IIP-32): Psychometric Properties and Factor Structure in Clinical and Non-clinical Groups.Front Psychol. 2018 Mar 19;9:341. doi: 10.3389/fpsyg.2018.00341. eCollection 2018.
1271 A Systems Genetics Approach Identified GPD1L and its Molecular Mechanism for Obesity in Human Adipose Tissue.Sci Rep. 2017 May 11;7(1):1799. doi: 10.1038/s41598-017-01517-6.
1272 The effect of combined diet and exercise intervention on body weight and the serum GPIHBP1 concentration in overweight/obese middle-aged women.Clin Chim Acta. 2017 Dec;475:109-115. doi: 10.1016/j.cca.2017.10.017. Epub 2017 Oct 19.
1273 Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels.J Lipid Res. 2006 Apr;47(4):761-6. doi: 10.1194/jlr.M500338-JLR200. Epub 2006 Jan 25.
1274 The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.Nat Commun. 2013;4:1968. doi: 10.1038/ncomms2968.
1275 G protein pathway suppressor 2 (GPS2) links inflammation and cholesterol efflux by controlling lipopolysaccharide-induced ATP-binding cassette transporter A1 expression in macrophages.FASEB J. 2019 Feb;33(2):1631-1643. doi: 10.1096/fj.201801123R. Epub 2018 Aug 28.
1276 Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity.Obes Facts. 2018;11(6):475-490. doi: 10.1159/000494295. Epub 2018 Dec 11.
1277 Effect of six type II diabetes susceptibility loci and an FTO variant on obesity in Pakistani subjects.Eur J Hum Genet. 2016 Jun;24(6):903-10. doi: 10.1038/ejhg.2015.212. Epub 2015 Sep 23.
1278 Translocase of inner mitochondrial membrane 44 alters the mitochondrial fusion and fission dynamics and protects from type 2 diabetes.Metabolism. 2015 Jun;64(6):677-88. doi: 10.1016/j.metabol.2015.02.004. Epub 2015 Feb 23.
1279 Guanylate Cyclase C: A Current Hot Target, from Physiology to Pathology.Curr Med Chem. 2018;25(16):1879-1908. doi: 10.2174/0929867325666171205150310.
1280 Increased level of DNA damage in some organs of obese Zucker rats by -H2AX analysis.Environ Mol Mutagen. 2017 Aug;58(7):477-484. doi: 10.1002/em.22115. Epub 2017 Jul 17.
1281 Lack of adipose-specific hexose-6-phosphate dehydrogenase causes inactivation of adipose glucocorticoids and improves metabolic phenotype in mice.Clin Sci (Lond). 2019 Nov 15;133(21):2189-2202. doi: 10.1042/CS20190679.
1282 Adipocyte differentiation is regulated by mitochondrial trifunctional protein -subunit via sirtuin 1.Exp Cell Res. 2017 Aug 15;357(2):271-281. doi: 10.1016/j.yexcr.2017.05.020. Epub 2017 May 26.
1283 Hyaluronan synthases (HAS1-3) in stromal and malignant cells correlate with breast cancer grade and predict patient survival.Breast Cancer Res Treat. 2014 Jan;143(2):277-86. doi: 10.1007/s10549-013-2804-7. Epub 2013 Dec 14.
1284 Adapting the Healthy Eating Index 2010 for the Canadian Population: Evidence from the Canadian National Nutrition Survey.Nutrients. 2017 Aug 21;9(8):910. doi: 10.3390/nu9080910.
1285 Protection against high-fat diet-induced obesity in Helz2-deficient male mice due to enhanced expression of hepatic leptin receptor.Endocrinology. 2014 Sep;155(9):3459-72. doi: 10.1210/en.2013-2160. Epub 2014 Jul 8.
1286 Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs.PLoS One. 2013;8(1):e53944. doi: 10.1371/journal.pone.0053944. Epub 2013 Jan 17.
1287 Hhip inhibits proliferation and promotes differentiation of adipocytes through suppressing hedgehog signaling pathway.Biochem Biophys Res Commun. 2019 Jun 18;514(1):148-156. doi: 10.1016/j.bbrc.2019.04.047. Epub 2019 Apr 24.
1288 Novel genes on rat chromosome 10 are linked to body fat mass, preadipocyte number and adipocyte size.Int J Obes (Lond). 2016 Dec;40(12):1832-1840. doi: 10.1038/ijo.2016.127. Epub 2016 Jul 27.
1289 Hemojuvelin: a new link between obesity and iron homeostasis.Obesity (Silver Spring). 2011 Aug;19(8):1545-51. doi: 10.1038/oby.2011.12. Epub 2011 Feb 10.
1290 Association of HLA-DRB3*0202 and serum IgG antibodies to Chlamydia pneumoniae with essential hypertension in a highly homogeneous population from Majorca (Balearic Islands, Spain).J Hum Hypertens. 2005 Aug;19(8):615-22. doi: 10.1038/sj.jhh.1001872.
1291 Altered intragenic DNA methylation of HOOK2 gene in adipose tissue from individuals with obesity and type 2 diabetes.PLoS One. 2017 Dec 11;12(12):e0189153. doi: 10.1371/journal.pone.0189153. eCollection 2017.
1292 Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits.Obesity (Silver Spring). 2016 Jan;24(1):51-9. doi: 10.1002/oby.21317. Epub 2015 Dec 9.
1293 In utero and lactational exposure to BDE-47 promotes obesity development in mouse offspring fed a high-fat diet: impaired lipid metabolism and intestinal dysbiosis.Arch Toxicol. 2018 May;92(5):1847-1860. doi: 10.1007/s00204-018-2177-0. Epub 2018 Mar 9.
1294 Inhibitory effects of fenretinide metabolites N-[4-methoxyphenyl]retinamide (MPR) and 4-oxo-N-(4-hydroxyphenyl)retinamide (3-keto-HPR) on fenretinide molecular targets -carotene oxygenase 1, stearoyl-CoA desaturase 1 and dihydroceramide 4-desaturase 1.PLoS One. 2017 Apr 27;12(4):e0176487. doi: 10.1371/journal.pone.0176487. eCollection 2017.
1295 Autoimmunity to HSP60 during diet induced obesity in mice.Int J Obes (Lond). 2017 Feb;41(2):348-351. doi: 10.1038/ijo.2016.216. Epub 2016 Nov 30.
1296 Polymorphisms in the oxygen-regulated protein 150 gene (ORP150) are associated with insulin resistance in Pima Indians.Diabetes. 2002 May;51(5):1618-21. doi: 10.2337/diabetes.51.5.1618.
1297 Genetic analysis of the IRS. Pleiotropic effects of genes influencing insulin levels on lipoprotein and obesity measures.Arterioscler Thromb Vasc Biol. 1996 Feb;16(2):281-8. doi: 10.1161/01.atv.16.2.281.
1298 Genetic contribution to C-reactive protein levels in severe obesity.Mol Genet Metab. 2012 Mar;105(3):494-501. doi: 10.1016/j.ymgme.2011.11.198. Epub 2011 Dec 2.
1299 Obesity and Insulin Resistance Promote Atherosclerosis through an IFN-Regulated Macrophage Protein Network.Cell Rep. 2018 Jun 5;23(10):3021-3030. doi: 10.1016/j.celrep.2018.05.010.
1300 The Angiogenesis Inhibitor ALS-L1023 from Lemon-Balm Leaves Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease through Regulating the Visceral Adipose-Tissue Function.Int J Mol Sci. 2017 Apr 17;18(4):846. doi: 10.3390/ijms18040846.
1301 Hydrodynamic delivery of IL-38 gene alleviates obesity-induced inflammation and insulin resistance.Biochem Biophys Res Commun. 2019 Jan 1;508(1):198-202. doi: 10.1016/j.bbrc.2018.11.114. Epub 2018 Nov 23.
1302 IL-34 promotes foam cell formation by enhancing CD36 expression through p38 MAPK pathway.Sci Rep. 2018 Nov 26;8(1):17347. doi: 10.1038/s41598-018-35485-2.
1303 Hepatic leptin receptor expression can partiallycompensate for IL-6R deficiency inDEN-induced hepatocellular carcinoma.Mol Metab. 2018 Nov;17:122-133. doi: 10.1016/j.molmet.2018.08.010. Epub 2018 Sep 5.
1304 Inhibition of 72 kDa inositol polyphosphate 5-phosphatase E improves insulin signal transduction in diet-induced obesity.J Endocrinol. 2013 Apr 15;217(2):131-40. doi: 10.1530/JOE-12-0562. Print 2013 May.
1305 INPPL1 gene mutations in opsismodysplasia.J Hum Genet. 2017 Feb;62(2):135-140. doi: 10.1038/jhg.2016.119. Epub 2016 Oct 6.
1306 The role of the genetic variants IRX3 rs3751723 and FTO rs9939609 in the obesity phenotypes of children and adolescents.Obes Res Clin Pract. 2019 Mar-Apr;13(2):137-142. doi: 10.1016/j.orcp.2019.01.005. Epub 2019 Jan 31.
1307 Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obese rodents and women.J Nutr. 2011 Jun;141(6):1172-80. doi: 10.3945/jn.110.127068. Epub 2011 Apr 20.
1308 Bilirubin reduces visceral obesity and insulin resistance by suppression of inflammatory cytokines.PLoS One. 2019 Oct 2;14(10):e0223302. doi: 10.1371/journal.pone.0223302. eCollection 2019.
1309 ITIH-5 expression in human adipose tissue is increased in obesity.Obesity (Silver Spring). 2012 Apr;20(4):708-14. doi: 10.1038/oby.2011.268. Epub 2011 Aug 18.
1310 The association of Val109Asp polymorphic marker of intelectin 1 gene with abdominal obesity in Kyrgyz population.BMC Endocr Disord. 2018 Feb 27;18(1):15. doi: 10.1186/s12902-018-0242-6.
1311 KRAS-induced actin-interacting protein: a potent target for obesity, diabetes and cancer.Anticancer Res. 2011 Jul;31(7):2413-7.
1312 The caveolae-associated coiled-coil protein, NECC2, regulates insulin signalling in Adipocytes.J Cell Mol Med. 2018 Nov;22(11):5648-5661. doi: 10.1111/jcmm.13840. Epub 2018 Aug 30.
1313 Lack of sex differences in high density lipoproteins in Pima Indians. Studies of obesity, lipase activities, and steroid hormones.Arteriosclerosis. 1987 May-Jun;7(3):292-300. doi: 10.1161/01.atv.7.3.292.
1314 85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells. Am J Physiol Gastrointest Liver Physiol. 2002 Apr;282(4):G586-97.
1315 The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice.J Biol Chem. 2017 Jun 2;292(22):9051-9062. doi: 10.1074/jbc.M116.771428. Epub 2017 Apr 19.
1316 KDM4B protects against obesity and metabolic dysfunction.Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5566-E5575. doi: 10.1073/pnas.1721814115. Epub 2018 May 29.
1317 Genetic and Clinical Profile of Chinese Patients with Autosomal Dominant Spastic Paraplegia.Mol Diagn Ther. 2019 Dec;23(6):781-789. doi: 10.1007/s40291-019-00426-w.
1318 A DNA methylation site within the KLF13 gene is associated with orexigenic processes based on neural responses and ghrelin levels.Int J Obes (Lond). 2017 Jun;41(6):990-994. doi: 10.1038/ijo.2017.43. Epub 2017 Feb 14.
1319 DNA methylation of the Klf14 gene region in whole blood cells provides prediction for the chronic inflammation in the adipose tissue.Biochem Biophys Res Commun. 2018 Mar 11;497(3):908-915. doi: 10.1016/j.bbrc.2017.12.104. Epub 2018 Feb 6.
1320 Correlation of TLR4 and KLF7 in Inflammation Induced by Obesity.Inflammation. 2017 Feb;40(1):42-51. doi: 10.1007/s10753-016-0450-z.
1321 Association of cardiovascular risk factors with disease severity in cerebral cavernous malformation type 1 subjects with the common Hispanic mutation.Cerebrovasc Dis. 2014;37(1):57-63. doi: 10.1159/000356839. Epub 2013 Dec 21.
1322 Novel Ultrasonographic Fatty Liver Indicator Can Predict Hepatitis in Children With Non-alcoholic Fatty Liver Disease.Front Pediatr. 2019 Jan 8;6:416. doi: 10.3389/fped.2018.00416. eCollection 2018.
1323 Analysis of MC4R rs17782313, POMC rs1042571, APOE-Hha1 and AGRP rs3412352 genetic variants with susceptibility to obesity risk in North Indians.Ann Hum Biol. 2016 May;43(3):285-8. doi: 10.3109/03014460.2015.1061597. Epub 2015 Jul 31.
1324 Variations in DNA elucidate molecular networks that cause disease.Nature. 2008 Mar 27;452(7186):429-35. doi: 10.1038/nature06757. Epub 2008 Mar 16.
1325 Biased signaling at neural melanocortin receptors in regulation of energy homeostasis.Biochim Biophys Acta Mol Basis Dis. 2017 Oct;1863(10 Pt A):2486-2495. doi: 10.1016/j.bbadis.2017.04.010. Epub 2017 Apr 19.
1326 LDB1 Regulates Energy Homeostasis During Diet-Induced Obesity.Endocrinology. 2017 May 1;158(5):1289-1297. doi: 10.1210/en.2016-1791.
1327 New players in high fat diet-induced obesity: LETM1 and CTMP.Metabolism. 2014 Mar;63(3):318-27. doi: 10.1016/j.metabol.2013.10.012. Epub 2013 Oct 31.
1328 Allyl Isothiocyanate Ameliorates Obesity by Inhibiting Galectin-12.Mol Nutr Food Res. 2018 Mar;62(6):e1700616. doi: 10.1002/mnfr.201700616. Epub 2018 Mar 12.
1329 Personalized Therapy Against Preeclampsia by Replenishing Placental Protein 13 (PP13) Targeted to Patients With Impaired PP13 Molecule or Function.Comput Struct Biotechnol J. 2017 Sep 22;15:433-446. doi: 10.1016/j.csbj.2017.09.002. eCollection 2017.
1330 A genome-wide association study on obesity and obesity-related traits.PLoS One. 2011 Apr 28;6(4):e18939. doi: 10.1371/journal.pone.0018939.
1331 A genetic variant in LINGO2 contributes to the risk of gestational diabetes mellitus in a Chinese population.J Cell Physiol. 2019 May;234(5):7012-7018. doi: 10.1002/jcp.27454. Epub 2018 Nov 13.
1332 Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles.BMC Genomics. 2018 Feb 14;19(1):145. doi: 10.1186/s12864-018-4515-2.
1333 Human but not mouse adipogenesis is critically dependent on LMO3.Cell Metab. 2013 Jul 2;18(1):62-74. doi: 10.1016/j.cmet.2013.05.020.
1334 Evidence for a role of LPGAT1 in influencing BMI and percent body fat in Native Americans.Obesity (Silver Spring). 2013 Jan;21(1):193-202. doi: 10.1002/oby.20243.
1335 Obesity- and age-related alterations in FAT/CD36 translocation and lipin-1 subcellular localization in skeletal muscle of the Zucker rats.Gen Physiol Biophys. 2017 Oct;36(4):399-406. doi: 10.4149/gpb_2017010. Epub 2017 Jun 27.
1336 Association of circulating proinflammatory marker, leucine-rich-2-glycoprotein (LRG1), following metabolic/bariatric surgery.Diabetes Metab Res Rev. 2018 Oct;34(7):e3029. doi: 10.1002/dmrr.3029. Epub 2018 Jul 23.
1337 Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants.PLoS One. 2007 Dec 26;2(12):e1361. doi: 10.1371/journal.pone.0001361.
1338 The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells.Oncotarget. 2016 May 10;7(19):27735-52. doi: 10.18632/oncotarget.8408.
1339 Impact of Different Estimation Methods on Obesity-Attributable Mortality Levels and Trends: The Case of The Netherlands.Int J Environ Res Public Health. 2018 Sep 29;15(10):2146. doi: 10.3390/ijerph15102146.
1340 DNA methylation of the LY86 gene is associated with obesity, insulin resistance, and inflammation.Twin Res Hum Genet. 2014 Jun;17(3):183-91. doi: 10.1017/thg.2014.22. Epub 2014 Apr 15.
1341 A Genomewide Integrative Analysis of GWAS and eQTLs Data Identifies Multiple Genes and Gene Sets Associated with Obesity.Biomed Res Int. 2018 May 8;2018:3848560. doi: 10.1155/2018/3848560. eCollection 2018.
1342 Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits.Cell Metab. 2019 Apr 2;29(4):932-949.e4. doi: 10.1016/j.cmet.2018.12.013. Epub 2019 Jan 10.
1343 Molecular Characterization and Functional Analysis of Leucine Zipper Transcription Factor Like 1 in Zebrafish (Danio rerio).Front Physiol. 2019 Jun 25;10:801. doi: 10.3389/fphys.2019.00801. eCollection 2019.
1344 Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults.Front Genet. 2018 Dec 12;9:654. doi: 10.3389/fgene.2018.00654. eCollection 2018.
1345 Polymorphisms in FTO and MAF Genes and Birth Weight, BMI, Ponderal Index, Weight Gain in a Large Cohort of Infants with a Birth Weight below 1500 Grams.PLoS One. 2013 Jun 26;8(6):e66331. doi: 10.1371/journal.pone.0066331. Print 2013.
1346 Emerging Roles for Maf1 beyond the Regulation of RNA Polymerase III Activity.J Mol Biol. 2015 Aug 14;427(16):2577-85. doi: 10.1016/j.jmb.2015.06.022. Epub 2015 Jul 11.
1347 Inhibition of PPAR, adipogenesis and insulin sensitivity by MAGED1.J Endocrinol. 2018 Nov 1;239(2):167-180. doi: 10.1530/JOE-18-0349.
1348 Schaaf-Yang syndrome shows a Prader-Willi syndrome-like phenotype during infancy.Orphanet J Rare Dis. 2019 Dec 2;14(1):277. doi: 10.1186/s13023-019-1249-4.
1349 MKK6 controls T3-mediated browning of white adipose tissue.Nat Commun. 2017 Oct 11;8(1):856. doi: 10.1038/s41467-017-00948-z.
1350 The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Chinese Hans from Shanghai.J Hum Genet. 2006;51(7):605-10. doi: 10.1007/s10038-006-0402-9. Epub 2006 May 13.
1351 Long-term supplementation of decaffeinated green tea extract does not modify body weight or abdominal obesity in a randomized trial of men at high risk for prostate cancer.Oncotarget. 2017 Jun 29;8(58):99093-99103. doi: 10.18632/oncotarget.18858. eCollection 2017 Nov 17.
1352 MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels.Nat Commun. 2016 Aug 31;7:12639. doi: 10.1038/ncomms12639.
1353 Science-based solutions to obesity: what are the roles of academia, government, industry, and health care?.Am J Clin Nutr. 2005 Jul;82(1 Suppl):207S-210S. doi: 10.1093/ajcn/82.1.207S.
1354 Resistin-induced stromal cell-derived factor-1 expression through Toll-like receptor 4 and activation of p38 MAPK/ NFB signaling pathway in gastric cancer cells.J Biomed Sci. 2014 Jun 14;21(1):59. doi: 10.1186/1423-0127-21-59.
1355 Obesity-induced MBD2_v2 expression promotes tumor-initiating triple-negative breast cancer stem cells.Mol Oncol. 2019 Apr;13(4):894-908. doi: 10.1002/1878-0261.12444. Epub 2019 Mar 1.
1356 A cryptic microdeletion including MBD5 occurring within the breakpoint of a reciprocal translocation between chromosomes 2 and 5 in a patient with developmental delay and obesity.Am J Med Genet A. 2013 Apr;161A(4):850-5. doi: 10.1002/ajmg.a.35768. Epub 2013 Mar 12.
1357 Obesity and Co-morbid Conditions Are Associated with Specific Neuropsychiatric Symptoms in Mild Cognitive Impairment.Front Aging Neurosci. 2017 May 29;9:164. doi: 10.3389/fnagi.2017.00164. eCollection 2017.
1358 Evidence of linkage and association with body fatness and abdominal fat on chromosome 15q26.Obesity (Silver Spring). 2007 Aug;15(8):2061-70. doi: 10.1038/oby.2007.245.
1359 MCU-knockdown attenuates high glucose-induced inflammation through regulating MAPKs/NF-B pathways and ROS production in HepG2 cells.PLoS One. 2018 Apr 30;13(4):e0196580. doi: 10.1371/journal.pone.0196580. eCollection 2018.
1360 Global nutrition 1990-2015: A shrinking hungry, and expanding fat world.PLoS One. 2018 Mar 27;13(3):e0194821. doi: 10.1371/journal.pone.0194821. eCollection 2018.
1361 The association of a HOPA polymorphism with major depression and phobia.Compr Psychiatry. 2002 Sep-Oct;43(5):404-10. doi: 10.1053/comp.2002.33489.
1362 Mesoderm-specific transcript localization in the ER and ER-lipid droplet interface supports a role in adipocyte hypertrophy.J Cell Biochem. 2018 Mar;119(3):2636-2645. doi: 10.1002/jcb.26429. Epub 2017 Dec 4.
1363 Increased Expression of Meteorin-Like Hormone in Type 2 Diabetes and Obesity and Its Association with Irisin.Cells. 2019 Oct 19;8(10):1283. doi: 10.3390/cells8101283.
1364 Aerobic Exercise Increases Meteorin-Like Protein in Muscle and Adipose Tissue of Chronic High-Fat Diet-Induced Obese Mice.Biomed Res Int. 2018 Apr 30;2018:6283932. doi: 10.1155/2018/6283932. eCollection 2018.
1365 The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.Mol Cell Biol. 2018 Jul 30;38(16):e00116-18. doi: 10.1128/MCB.00116-18. Print 2018 Aug 15.
1366 Association between SNPs and haplotypes in the METTL21C gene and peak bone mineral density and body composition in Chinese male nuclear families.J Bone Miner Metab. 2017 Jul;35(4):437-447. doi: 10.1007/s00774-016-0774-7. Epub 2016 Sep 14.
1367 MFAP2 promotes epithelial-mesenchymal transition in gastric cancer cells by activating TGF-/SMAD2/3 signaling pathway.Onco Targets Ther. 2018 Jul 12;11:4001-4017. doi: 10.2147/OTT.S160831. eCollection 2018.
1368 MFAP5 is related to obesity-associated adipose tissue and extracellular matrix remodeling and inflammation.Obesity (Silver Spring). 2015 Jul;23(7):1371-8. doi: 10.1002/oby.21103. Epub 2015 Jun 5.
1369 Hyperexpression of N-acetylglucosaminyltransferase-III in liver tissues of transgenic mice causes fatty body and obesity through severe accumulation of Apo A-I and Apo B.Arch Biochem Biophys. 2004 Jun 1;426(1):18-31. doi: 10.1016/j.abb.2003.12.039.
1370 Transcriptional and Translational Modulation of myo-Inositol Oxygenase (Miox) by Fatty Acids: IMPLICATIONS IN RENAL TUBULAR INJURY INDUCED IN OBESITY AND DIABETES.J Biol Chem. 2016 Jan 15;291(3):1348-67. doi: 10.1074/jbc.M115.698191. Epub 2015 Nov 17.
1371 Diet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase 19-deficient mice.Mol Cell Biol. 2004 Jun;24(12):5304-13. doi: 10.1128/MCB.24.12.5304-5313.2004.
1372 Genetic modifiers of Leprfa associated with variability in insulin production and susceptibility to NIDDM.Genomics. 1997 May 1;41(3):332-44. doi: 10.1006/geno.1997.4672.
1373 An integrated approach of comparative genomics and heritability analysis of pig and human on obesity trait: evidence for candidate genes on human chromosome 2.BMC Genomics. 2012 Dec 19;13:711. doi: 10.1186/1471-2164-13-711.
1374 The MTHFD1 1958G>A variant is associated with elevated C-reactive protein and body mass index in Canadian women from a premature birth cohort.Mol Genet Metab. 2014 Mar;111(3):390-392. doi: 10.1016/j.ymgme.2013.12.004. Epub 2013 Dec 11.
1375 Recapitulation of genome-wide association studies on body mass index in the Korean population.Int J Obes (Lond). 2012 Aug;36(8):1127-30. doi: 10.1038/ijo.2011.202. Epub 2011 Nov 1.
1376 Mice lacking myotubularin-related protein 14 show accelerated high-fat diet-induced lipid accumulation and inflammation.J Physiol Biochem. 2017 Feb;73(1):17-28. doi: 10.1007/s13105-016-0520-6. Epub 2016 Nov 2.
1377 The MTMR9 rs2293855 polymorphism is associated with glucose tolerance, insulin secretion, insulin sensitivity and increased risk of prediabetes.Gene. 2014 Aug 10;546(2):150-5. doi: 10.1016/j.gene.2014.06.028. Epub 2014 Jun 14.
1378 Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-B signaling mediated inflammation.Nat Commun. 2019 Apr 17;10(1):1801. doi: 10.1038/s41467-019-09588-x.
1379 Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes.Stem Cell Reports. 2015 Oct 13;5(4):569-81. doi: 10.1016/j.stemcr.2015.08.007. Epub 2015 Sep 10.
1380 Effect of obesity on the association between MYL2 (rs3782889) and high-density lipoprotein cholesterol among Korean men.J Hum Genet. 2016 May;61(5):405-9. doi: 10.1038/jhg.2015.165. Epub 2016 Jan 14.
1381 MYT1L mutation in a patient causes intellectual disability and early onset of obesity: a case report and review of the literature.J Pediatr Endocrinol Metab. 2019 Apr 24;32(4):409-413. doi: 10.1515/jpem-2018-0505.
1382 Novel hormone-regulated genes in visceral adipose tissue: cloning and identification of proinflammatory cytokine-like mouse and human MEDA-7: implications for obesity, insulin resistance and the metabolic syndrome.Diabetologia. 2011 Sep;54(9):2368-80. doi: 10.1007/s00125-011-2212-7. Epub 2011 Jun 19.
1383 Diet diversity and nutritional status among adults in southwest China.PLoS One. 2017 Feb 23;12(2):e0172406. doi: 10.1371/journal.pone.0172406. eCollection 2017.
1384 Large copy-number variations are enriched in cases with moderate to extreme obesity.Diabetes. 2010 Oct;59(10):2690-4. doi: 10.2337/db10-0192. Epub 2010 Jul 9.
1385 Combined effect of established BMI loci on obesity-related traits in an Algerian population sample.BMC Genet. 2014 Nov 25;15:128. doi: 10.1186/s12863-014-0128-1.
1386 Association of NCOA2 gene polymorphisms with obesity and dyslipidemia in the Chinese Han population.Int J Clin Exp Pathol. 2015 Jun 1;8(6):7341-9. eCollection 2015.
1387 Role of NCoR1 in mitochondrial function and energy metabolism.Cell Biol Int. 2018 Jun;42(6):734-741. doi: 10.1002/cbin.10973. Epub 2018 May 8.
1388 Natural Killer Cells from the Subcutaneous Adipose Tissue Underexpress the NKp30 and NKp44 in Obese Persons and Are Less Active against Major Histocompatibility Complex Class I Non-Expressing Neoplastic Cells.Front Immunol. 2017 Nov 7;8:1486. doi: 10.3389/fimmu.2017.01486. eCollection 2017.
1389 NCS-1 Deficiency Is Associated With Obesity and Diabetes Type 2 in Mice.Front Mol Neurosci. 2019 Apr 3;12:78. doi: 10.3389/fnmol.2019.00078. eCollection 2019.
1390 NDRG4 stratifies the prognostic value of body mass index in colorectal cancer.Oncotarget. 2016 Jan 12;7(2):1311-22. doi: 10.18632/oncotarget.6182.
1391 The impacts of the interaction of genetic variation, CYP112 and NEDD4L, with sodium intake on pediatric obesity with gender difference: a 3-year panel study.Int J Obes (Lond). 2017 Apr;41(4):542-550. doi: 10.1038/ijo.2016.232. Epub 2016 Dec 26.
1392 Variable penetrance of metabolic phenotypes and development of high-fat diet-induced adiposity in NEIL1-deficient mice.Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E724-34. doi: 10.1152/ajpendo.00387.2010. Epub 2011 Feb 1.
1393 Autosomal inheritance of diabetes in two families characterized by obesity and a novel H241Q mutation in NEUROD1.Pediatr Diabetes. 2008 Aug;9(4 Pt 2):367-72. doi: 10.1111/j.1399-5448.2008.00379.x. Epub 2008 Mar 5.
1394 NFATc3 deficiency reduces the classical activation of adipose tissue macrophages.J Mol Endocrinol. 2018 Oct 1;61(3):79-89. doi: 10.1530/JME-18-0070.
1395 Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.Nat Med. 2018 Mar;24(3):292-303. doi: 10.1038/nm.4481. Epub 2018 Feb 5.
1396 Obesity-induced endoplasmic reticulum stress suppresses nuclear factor-Y expression.Mol Cell Biochem. 2017 Feb;426(1-2):47-54. doi: 10.1007/s11010-016-2879-7. Epub 2016 Nov 12.
1397 Snoring and breathing pauses during sleep: interview survey of a United Kingdom population sample reveals a significant increase in the rates of sleep apnoea and obesity over the last 20 years - data from the UK sleep survey.Sleep Med. 2019 Feb;54:250-256. doi: 10.1016/j.sleep.2018.08.029. Epub 2018 Oct 9.
1398 Neuroligin 2 nonsense variant associated with anxiety, autism, intellectual disability, hyperphagia, and obesity.Am J Med Genet A. 2017 Jan;173(1):213-216. doi: 10.1002/ajmg.a.37977. Epub 2016 Nov 16.
1399 The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis.Cell Host Microbe. 2018 Sep 12;24(3):364-378.e6. doi: 10.1016/j.chom.2018.08.009.
1400 Outcomes of aortic valve replacement via partial upper sternotomy versus conventional aortic valve replacement in obese patients.Interact Cardiovasc Thorac Surg. 2018 Oct 1;27(4):481-486. doi: 10.1093/icvts/ivy083.
1401 Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice.Mol Metab. 2018 Dec;18:97-106. doi: 10.1016/j.molmet.2018.09.001. Epub 2018 Sep 15.
1402 Diet-dependent obesity and hypercholesterolemia in the New Zealand obese mouse: identification of a quantitative trait locus for elevated serum cholesterol on the distal mouse chromosome 5.Biochem Biophys Res Commun. 2003 May 16;304(4):812-7. doi: 10.1016/s0006-291x(03)00664-8.
1403 Noggin depletion in adipocytes promotes obesity in mice.Mol Metab. 2019 Jul;25:50-63. doi: 10.1016/j.molmet.2019.04.004. Epub 2019 Apr 10.
1404 Endothelial dysfunction is associated with impaired lung function in two independent community cohorts.Respir Med. 2018 Oct;143:123-128. doi: 10.1016/j.rmed.2018.09.009. Epub 2018 Sep 12.
1405 A favorable cardiometabolic profile is associated with the G allele of the genetic variant rs5068 in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA).PLoS One. 2017 Dec 18;12(12):e0189858. doi: 10.1371/journal.pone.0189858. eCollection 2017.
1406 15q24.1 BP4-BP1 microdeletion unmasking paternally inherited functional polymorphisms combined with distal 15q24.2q24.3 duplication in a patient with epilepsy, psychomotor delay, overweight, ventricular arrhythmia.Eur J Med Genet. 2018 Aug;61(8):459-464. doi: 10.1016/j.ejmg.2018.03.005. Epub 2018 Mar 14.
1407 Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice.Metabolism. 2018 Oct;87:87-97. doi: 10.1016/j.metabol.2018.07.003. Epub 2018 Jul 31.
1408 Distinct roles of TRAF6 and TAK1 in the regulation of adipocyte survival, thermogenesis program, and high-fat diet-induced obesity.Oncotarget. 2017 Nov 3;8(68):112565-112583. doi: 10.18632/oncotarget.22575. eCollection 2017 Dec 22.
1409 Skeletal Muscle Nucleo-Mitochondrial Crosstalk in Obesity and Type 2 Diabetes.Int J Mol Sci. 2017 Apr 14;18(4):831. doi: 10.3390/ijms18040831.
1410 Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway.Diabetes. 2019 Jun;68(6):1329-1340. doi: 10.2337/db18-1009. Epub 2019 Apr 1.
1411 Can Nesfatin-1 Predict Hypertension in Obese Children?.J Clin Res Pediatr Endocrinol. 2020 Mar 19;12(1):29-36. doi: 10.4274/jcrpe.galenos.2019.2019.0072. Epub 2019 Jul 24.
1412 Nupr1 deletion protects against glucose intolerance by increasing beta cell mass.Diabetologia. 2013 Nov;56(11):2477-86. doi: 10.1007/s00125-013-3006-x. Epub 2013 Jul 31.
1413 Maternal BMI as a predictor of methylation of obesity-related genes in saliva samples from preschool-age Hispanic children at-risk for obesity.BMC Genomics. 2017 Jan 9;18(1):57. doi: 10.1186/s12864-016-3473-9.
1414 Conditional knock-out reveals a requirement for O-linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis.J Biol Chem. 2015 Mar 13;290(11):7097-113. doi: 10.1074/jbc.M114.617779. Epub 2015 Jan 16.
1415 Possible involvement of Opa-interacting protein 5 in adipose proliferation and obesity.PLoS One. 2014 Feb 6;9(2):e87661. doi: 10.1371/journal.pone.0087661. eCollection 2014.
1416 Upregulation of intestinal glucose transporters after Roux-en-Y gastric bypass to prevent carbohydrate malabsorption.Obesity (Silver Spring). 2014 Oct;22(10):2164-71. doi: 10.1002/oby.20829. Epub 2014 Jul 2.
1417 Association of OSBPL11 gene polymorphisms with cardiovascular disease risk factors in obesity.Obesity (Silver Spring). 2009 Jul;17(7):1466-72. doi: 10.1038/oby.2009.71. Epub 2009 Mar 26.
1418 Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety.Mol Metab. 2017 Nov;6(11):1419-1428. doi: 10.1016/j.molmet.2017.08.006. Epub 2017 Aug 24.
1419 Association Study of Three Gene Polymorphisms Recently Identified by a Genome-Wide Association Study with Obesity-Related Phenotypes in Chinese Children.Obes Facts. 2017;10(3):179-190. doi: 10.1159/000471487. Epub 2017 Jun 1.
1420 Pannexin 1 regulates adipose stromal cell differentiation and fat accumulation.Sci Rep. 2018 Nov 1;8(1):16166. doi: 10.1038/s41598-018-34234-9.
1421 PAQR3 has modulatory roles in obesity, energy metabolism, and leptin signaling.Endocrinology. 2013 Dec;154(12):4525-35. doi: 10.1210/en.2013-1633. Epub 2013 Sep 13.
1422 The modifier effect of the BDNF gene in the phenotype of the WAGRO syndrome.Gene. 2013 Mar 10;516(2):285-90. doi: 10.1016/j.gene.2012.11.073. Epub 2012 Dec 21.
1423 Phosducin rs12402521 polymorphism predicts development of hypertension in young subjects with overweight or obesity.Nutr Metab Cardiovasc Dis. 2013 Apr;23(4):323-9. doi: 10.1016/j.numecd.2011.08.004. Epub 2012 Feb 23.
1424 Inhibition of pyruvate dehydrogenase kinase-4 by l-glutamine protects pregnant rats against fructose-induced obesity and hepatic lipid accumulation.Biomed Pharmacother. 2019 Feb;110:59-67. doi: 10.1016/j.biopha.2018.11.038. Epub 2018 Nov 19.
1425 Gene expression and epigenetic aberrations in F1-placentas fathered by obese males.Mol Reprod Dev. 2017 Apr;84(4):316-328. doi: 10.1002/mrd.22784. Epub 2017 Mar 3.
1426 Associations of metabolic parameters and ethanol consumption with messenger RNA expression of clock genes in healthy men.Chronobiol Int. 2010 Jan;27(1):194-203. doi: 10.3109/07420520903398617.
1427 Exome sequencing reveals novel genetic loci influencing obesity-related traits in Hispanic children.Obesity (Silver Spring). 2017 Jul;25(7):1270-1276. doi: 10.1002/oby.21869. Epub 2017 May 16.
1428 Pex11a deficiency causes dyslipidaemia and obesity in mice.J Cell Mol Med. 2019 Mar;23(3):2020-2031. doi: 10.1111/jcmm.14108. Epub 2018 Dec 25.
1429 The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress.EBioMedicine. 2016 Jan 29;5:82-92. doi: 10.1016/j.ebiom.2016.01.031. eCollection 2016 Mar.
1430 Epigenetic regulation of adipogenesis by PHF2 histone demethylase.Diabetes. 2013 May;62(5):1426-34. doi: 10.2337/db12-0628. Epub 2012 Dec 28.
1431 Protein and gene expression analysis of Phf6, the gene mutated in the Brjeson-Forssman-Lehmann Syndrome of intellectual disability and obesity.Gene Expr Patterns. 2007 Oct;7(8):858-71. doi: 10.1016/j.modgep.2007.06.007. Epub 2007 Jul 6.
1432 Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance.Diabetologia. 2011 Jul;54(7):1879-87. doi: 10.1007/s00125-011-2116-6. Epub 2011 Apr 1.
1433 A role for protein inhibitor of activated STAT1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors.J Biol Chem. 2012 Nov 2;287(45):37973-85. doi: 10.1074/jbc.M112.403139. Epub 2012 Sep 11.
1434 Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity.Mol Endocrinol. 2013 Sep;27(9):1518-35. doi: 10.1210/me.2013-1048. Epub 2013 Aug 8.
1435 The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity.Cell Metab. 2014 Jul 1;20(1):119-32. doi: 10.1016/j.cmet.2014.05.002. Epub 2014 Jun 5.
1436 Group VIA phospholipase A2 deficiency in mice chronically fed with high-fat-diet attenuates hepatic steatosis by correcting a defect of phospholipid remodeling.Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):662-676. doi: 10.1016/j.bbalip.2019.01.012. Epub 2019 Feb 5.
1437 Newborns of obese parents have altered DNA methylation patterns at imprinted genes.Int J Obes (Lond). 2015 Apr;39(4):650-7. doi: 10.1038/ijo.2013.193. Epub 2013 Oct 25.
1438 Perilipin-2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra-hepatocyte actions.J Physiol. 2019 Mar;597(6):1565-1584. doi: 10.1113/JP277140. Epub 2019 Jan 2.
1439 The role of perilipin in human obesity and insulin resistance.Curr Opin Lipidol. 2007 Apr;18(2):152-6. doi: 10.1097/MOL.0b013e328086aeab.
1440 Relationship between perilipin gene polymorphisms and body weight and body composition during weight loss and weight maintenance.Physiol Behav. 2009 Mar 23;96(4-5):723-8. doi: 10.1016/j.physbeh.2009.01.011.
1441 Role of Omentin, Vaspin, Cardiotrophin-1, TWEAK and NOV/CCN3 in Obesity and Diabetes Development.Int J Mol Sci. 2017 Aug 15;18(8):1770. doi: 10.3390/ijms18081770.
1442 Deciphering adipose tissue heterogeneity.Ann N Y Acad Sci. 2018 Jan;1411(1):5-20. doi: 10.1111/nyas.13398. Epub 2017 Aug 1.
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1448 Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability.Am J Hum Genet. 2016 Feb 4;98(2):363-72. doi: 10.1016/j.ajhg.2015.12.014. Epub 2016 Jan 28.
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1451 Ablation of PPP1R3G reduces glycogen deposition and mitigates high-fat diet induced obesity.Mol Cell Endocrinol. 2017 Jan 5;439:133-140. doi: 10.1016/j.mce.2016.10.036. Epub 2016 Nov 2.
1452 PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis.PLoS Genet. 2015 Oct 6;11(10):e1005561. doi: 10.1371/journal.pgen.1005561. eCollection 2015 Oct.
1453 Long-term follow-up of the German post-market study for upper airway stimulation for obstructive sleep apnea.Sleep Breath. 2020 Sep;24(3):979-984. doi: 10.1007/s11325-019-01933-0. Epub 2019 Sep 4.
1454 Gain of Metabolic Benefit with Ablation of miR-149-3p from Subcutaneous Adipose Tissue in Diet-Induced Obese Mice.Mol Ther Nucleic Acids. 2019 Dec 6;18:194-203. doi: 10.1016/j.omtn.2019.07.024. Epub 2019 Aug 26.
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1456 PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced obese mice.Cell Death Dis. 2018 Aug 29;9(9):876. doi: 10.1038/s41419-018-0904-3.
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1458 Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants.Mol Metab. 2017 Nov;6(11):1503-1516. doi: 10.1016/j.molmet.2017.08.012. Epub 2017 Sep 1.
1459 Metabolomic Study of Obesity and Its Treatment with Palmitoylated Prolactin-Releasing Peptide Analog in Spontaneously Hypertensive and Normotensive Rats.J Proteome Res. 2019 Apr 5;18(4):1735-1750. doi: 10.1021/acs.jproteome.8b00964. Epub 2019 Mar 11.
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1461 Arginine methylation of CRTC2 is critical in the transcriptional control of hepatic glucose metabolism.Sci Signal. 2014 Feb 25;7(314):ra19. doi: 10.1126/scisignal.2004479.
1462 New roles for prokineticin 2 in feeding behavior, insulin resistance and type 2 diabetes: Studies in mice and humans.Mol Metab. 2019 Nov;29:182-196. doi: 10.1016/j.molmet.2019.08.016. Epub 2019 Aug 28.
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1464 Genetic association analysis of polymorphisms in PSD3 gene with obesity, type 2 diabetes, and HDL cholesterol.Diabetes Res Clin Pract. 2017 Apr;126:105-114. doi: 10.1016/j.diabres.2017.02.006. Epub 2017 Feb 10.
1465 Mutations in -secretase subunit-encoding PSENEN underlie Dowling-Degos disease associated with acne inversa. J Clin Invest. 2017 Apr 3;127(4):1485-1490. doi: 10.1172/JCI90667. Epub 2017 Mar 13.
1466 Lifetime Self-Harm Behaviors Are Not More Prevalent in Bariatric Surgery Candidates than in Community Controls with Obesity.Obes Facts. 2018;11(2):109-115. doi: 10.1159/000486484. Epub 2018 Apr 10.
1467 Loss of p27 Associated with Risk for Endometrial Carcinoma Arising in the Setting of Obesity.Curr Mol Med. 2016;16(3):252-65. doi: 10.2174/1566524016666160225153307.
1468 RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs.J Clin Invest. 2017 Mar 1;127(3):987-1004. doi: 10.1172/JCI89484. Epub 2017 Feb 13.
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1470 2-OHOA supplementation reduced adiposity and improved cardiometabolic risk to a greater extent than n-3 PUFA in obese mice.Obes Res Clin Pract. 2019 Nov-Dec;13(6):579-585. doi: 10.1016/j.orcp.2019.10.009. Epub 2019 Nov 29.
1471 Inter-Tissue Gene Co-Expression Networks between Metabolically Healthy and Unhealthy Obese Individuals.PLoS One. 2016 Dec 1;11(12):e0167519. doi: 10.1371/journal.pone.0167519. eCollection 2016.
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1473 Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity.Cardiovasc Res. 2019 Nov 1;115(13):1861-1872. doi: 10.1093/cvr/cvz068.
1474 Pygo2 Regulates Adiposity and Glucose Homeostasis via -Catenin-Axin2-GSK3 Signaling Pathway.Diabetes. 2018 Dec;67(12):2569-2584. doi: 10.2337/db18-0311. Epub 2018 Oct 2.
1475 A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity.Int J Obes (Lond). 2015 Feb;39(2):295-302. doi: 10.1038/ijo.2014.96. Epub 2014 Jun 3.
1476 Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children.Diabetes. 2008 Feb;57(2):494-502. doi: 10.2337/db07-1273. Epub 2007 Oct 31.
1477 Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity.PLoS One. 2011;6(7):e22931. doi: 10.1371/journal.pone.0022931. Epub 2011 Jul 28.
1478 Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance.Cell Rep. 2018 Dec 18;25(12):3329-3341.e5. doi: 10.1016/j.celrep.2018.11.083.
1479 Mice lacking RAP1 show early onset and higher rates of DEN-induced hepatocellular carcinomas in female mice.PLoS One. 2018 Oct 11;13(10):e0204909. doi: 10.1371/journal.pone.0204909. eCollection 2018.
1480 Chemerin Isoforms and Activity in Obesity.Int J Mol Sci. 2019 Mar 5;20(5):1128. doi: 10.3390/ijms20051128.
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1482 Modulation of genetic associations with serum urate levels by body-mass-index in humans.PLoS One. 2015 Mar 26;10(3):e0119752. doi: 10.1371/journal.pone.0119752. eCollection 2015.
1483 A single extra copy of Down syndrome critical region 1-4 results in impaired hepatic glucose homeostasis.Mol Metab. 2019 Mar;21:82-89. doi: 10.1016/j.molmet.2018.12.002. Epub 2018 Dec 5.
1484 Rcan2 and estradiol independently regulate body weight in female mice.Oncotarget. 2017 Jul 18;8(29):48098-48109. doi: 10.18632/oncotarget.18259.
1485 Liver-specific Repin1 deficiency impairs transient hepatic steatosis in liver regeneration.Sci Rep. 2018 Nov 15;8(1):16858. doi: 10.1038/s41598-018-35325-3.
1486 The effect of BMI on haemostasis: Implications for thrombosis in women's health.Thromb Res. 2017 Mar;151 Suppl 1:S53-S55. doi: 10.1016/S0049-3848(17)30068-3.
1487 Multiple genetic variations confer risks for obesity and type 2 diabetes mellitus in arab descendants from UAE.Int J Obes (Lond). 2018 Jul;42(7):1345-1353. doi: 10.1038/s41366-018-0057-6. Epub 2018 Mar 12.
1488 The CHIRPY DRAGON intervention in preventing obesity in Chinese primary-school--aged children: Acluster-randomised controlled trial.PLoS Med. 2019 Nov 26;16(11):e1002971. doi: 10.1371/journal.pmed.1002971. eCollection 2019 Nov.
1489 Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14.Aging Cell. 2018 Aug;17(4):e12751. doi: 10.1111/acel.12751. Epub 2018 Apr 14.
1490 Identification of rs7350481 at chromosome 11q23.3 as a novel susceptibility locus for metabolic syndrome in Japanese individuals by an exome-wide association study.Oncotarget. 2017 Jun 13;8(24):39296-39308. doi: 10.18632/oncotarget.16945.
1491 Polymorphisms in endothelin system genes, arsenic levels and obesity risk.PLoS One. 2015 Mar 23;10(3):e0118471. doi: 10.1371/journal.pone.0118471. eCollection 2015.
1492 Expression of two inflammation-related genes (RIPK3 and RNF216) in mononuclear cells is associated with weight-loss regain in obese subjects.J Nutrigenet Nutrigenomics. 2009;2(2):78-84. doi: 10.1159/000210452. Epub 2009 Apr 2.
1493 Association of fat mass and obesity-associated and retinitis pigmentosa guanosine triphosphatase (GTPase) regulator-interacting protein-1 like polymorphisms with body mass index in Chinese women.Endocr J. 2018 Jul 28;65(7):783-791. doi: 10.1507/endocrj.EJ17-0554. Epub 2018 Apr 14.
1494 Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development.JCI Insight. 2019 Feb 7;4(3):e123337. doi: 10.1172/jci.insight.123337.
1495 Protection against High-Fat-Diet-Induced Obesity in MDM2(C305F) Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure.Cell Rep. 2017 Jan 24;18(4):1005-1018. doi: 10.1016/j.celrep.2016.12.086.
1496 Seasonal effects of the UCP3 and the RPTOR gene polymorphisms on obesity traits in Japanese adults.J Physiol Anthropol. 2014 Dec 22;33(1):38. doi: 10.1186/1880-6805-33-38.
1497 Correlates and inequality of underweight and overweight among women of reproductive age: Evidence from the 2016 Nepal Demographic Health Survey.PLoS One. 2019 May 10;14(5):e0216644. doi: 10.1371/journal.pone.0216644. eCollection 2019.
1498 Maresin 1 inhibits TNF-alpha-induced lipolysis and autophagy in 3T3-L1 adipocytes.J Cell Physiol. 2018 Mar;233(3):2238-2246. doi: 10.1002/jcp.26096. Epub 2017 Aug 30.
1499 Increased Reticulon 3 (RTN3) Leads to Obesity and Hypertriglyceridemia by Interacting With Heat Shock Protein Family A (Hsp70) Member 5 (HSPA5).Circulation. 2018 Oct 23;138(17):1828-1838. doi: 10.1161/CIRCULATIONAHA.117.030718.
1500 Bidirectional Association Between Psoriasis and Obesity: Benefits and Risks.J Interferon Cytokine Res. 2018 Jan;38(1):12-19. doi: 10.1089/jir.2017.0105. Epub 2017 Dec 18.
1501 Serum amyloid A attenuates cellular insulin sensitivity by increasing JNK activity in 3T3-L1 adipocytes.J Endocrinol Invest. 2009 Jul;32(7):568-75. doi: 10.1007/BF03346510. Epub 2009 Mar 26.
1502 SCAPER localizes to primary cilia and its mutation affects cilia length, causing Bardet-Biedl syndrome. Eur J Hum Genet. 2019 Jun;27(6):928-940. doi: 10.1038/s41431-019-0347-z. Epub 2019 Feb 5.
1503 Genome-wide copy number variation analysis identifies novel candidate loci associated with pediatric obesity.Eur J Hum Genet. 2018 Nov;26(11):1588-1596. doi: 10.1038/s41431-018-0189-0. Epub 2018 Jul 5.
1504 Rapidly Progressive Nephronophthisis in a 2-Year-Old Boy with a Homozygous SDCCAG8 Mutation.Tohoku J Exp Med. 2019 Sep;249(1):29-32. doi: 10.1620/tjem.249.29.
1505 Selenate Prevents Adipogenesis through Induction of Selenoprotein S and Attenuation of Endoplasmic Reticulum Stress.Molecules. 2018 Nov 5;23(11):2882. doi: 10.3390/molecules23112882.
1506 Senp2 regulates adipose lipid storage by de-SUMOylation of Setdb1.J Mol Cell Biol. 2018 Jun 1;10(3):258-266. doi: 10.1093/jmcb/mjx055.
1507 The cytoskeletal protein septin 11 is associated with human obesity and is involved in adipocyte lipid storage and metabolism.Diabetologia. 2017 Feb;60(2):324-335. doi: 10.1007/s00125-016-4155-5. Epub 2016 Nov 19.
1508 Infectobesity: obesity of infectious origin.J Nutr. 2001 Oct;131(10):2794S-2797S. doi: 10.1093/jn/131.10.2794S.
1509 Idiopathic gonadotrophin deficiency: genetic questions addressed through phenotypic characterization.Clin Endocrinol (Oxf). 2001 Aug;55(2):163-74. doi: 10.1046/j.1365-2265.2001.01277.x.
1510 Obesity paradox in the era of percutaneous coronary intervention with 2nd-generation drug-eluting stents: an analysis of a multicenter PCI registry.Heart Vessels. 2019 Feb;34(2):218-226. doi: 10.1007/s00380-018-1234-1. Epub 2018 Jul 31.
1511 Recent advances in molecular genetics of cardiovascular disorders. Implications for atherosclerosis and diseases of cellular lipid metabolism.Pathol Oncol Res. 1998;4(2):152-60.
1512 The effects of diet induced obesity on breast cancer associated pathways in mice deficient in SFRP1.Mol Cancer. 2014 May 22;13:117. doi: 10.1186/1476-4598-13-117.
1513 Tissue restricted expression of two human Frzbs in preadipocytes and pancreas.Biochem Biophys Res Commun. 1998 Jun 18;247(2):287-93. doi: 10.1006/bbrc.1998.8784.
1514 Umbilical Cord SFRP5 Levels of Term Newborns in Relation to Normal and Excessive Gestational Weight Gain.Int J Mol Sci. 2019 Jan 30;20(3):595. doi: 10.3390/ijms20030595.
1515 Introduction: Impacting the Social Determinants of Health through a Regional Academic-Community Partnership: The Experience of the Mid-South Transdisciplinary Collaborative Center for Health Disparities Research.Ethn Dis. 2017 Nov 9;27(Suppl 1):277-286. doi: 10.18865/ed.27.S1.277. eCollection 2017.
1516 Genetic association studies of obesity in Africa: a systematic review.Obes Rev. 2015 Mar;16(3):259-72. doi: 10.1111/obr.12260. Epub 2015 Feb 2.
1517 Reducing plasma membrane sphingomyelin increases insulin sensitivity.Mol Cell Biol. 2011 Oct;31(20):4205-18. doi: 10.1128/MCB.05893-11. Epub 2011 Aug 15.
1518 Relation Between Lead Exposure and Trends in Blood Pressure in Children.Am J Cardiol. 2018 Dec 1;122(11):1890-1895. doi: 10.1016/j.amjcard.2018.08.033. Epub 2018 Sep 7.
1519 p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans.Diabetologia. 2015 Oct;58(10):2352-60. doi: 10.1007/s00125-015-3667-8. Epub 2015 Jun 30.
1520 Seabuckthorn Leaves Extract and Flavonoid Glycosides Extract from Seabuckthorn Leaves Ameliorates Adiposity, Hepatic Steatosis, Insulin Resistance, and Inflammation in Diet-Induced Obesity.Nutrients. 2017 Jun 2;9(6):569. doi: 10.3390/nu9060569.
1521 Adherence to the Mediterranean Diet and Circulating Levels of Sirtuin 4 in Obese Patients: A Novel Association.Oxid Med Cell Longev. 2017;2017:6101254. doi: 10.1155/2017/6101254. Epub 2017 Jun 15.
1522 SIRT7 functions in redox homeostasis and cytoskeletal organization during oocyte maturation.FASEB J. 2018 Jun 7:fj201800078RR. doi: 10.1096/fj.201800078RR. Online ahead of print.
1523 Phospholamban deficiency does not alter skeletal muscle SERCA pumping efficiency or predispose mice to diet-induced obesity.Am J Physiol Endocrinol Metab. 2019 Mar 1;316(3):E432-E442. doi: 10.1152/ajpendo.00288.2018. Epub 2019 Jan 2.
1524 Genetic variations in regulatory pathways of fatty acid and glucose metabolism are associated with obesity phenotypes: a population-based cohort study.Int J Obes (Lond). 2009 Oct;33(10):1143-52. doi: 10.1038/ijo.2009.152. Epub 2009 Aug 4.
1525 Identification of genetic loci associated with different responses to high-fat diet-induced obesity in C57BL/6N and C57BL/6J substrains.Physiol Genomics. 2014 Jun 1;46(11):377-84. doi: 10.1152/physiolgenomics.00014.2014. Epub 2014 Apr 1.
1526 Regulation of insulin-response element binding protein-1 in obesity and diabetes: potential role in impaired insulin-induced gene transcription.Endocrinology. 2008 Oct;149(10):4829-36. doi: 10.1210/en.2007-1693. Epub 2008 Jun 19.
1527 FTO rs 9939609 SNP Is Associated With Adiponectin and Leptin Levels and the Risk of Obesity in a Cohort of Romanian Children Population.Medicine (Baltimore). 2016 May;95(20):e3709. doi: 10.1097/MD.0000000000003709.
1528 Polymorphisms in the SNRPN gene are associated with obesity susceptibility in a Spanish population.J Gene Med. 2017 May;19(5). doi: 10.1002/jgm.2956.
1529 SOCS2 modulates adipose tissue inflammation and expansion in mice.J Nutr Biochem. 2020 Feb;76:108304. doi: 10.1016/j.jnutbio.2019.108304. Epub 2019 Nov 23.
1530 Common variants in SOCS7 gene predict obesity, disturbances in lipid metabolism and insulin resistance.Nutr Metab Cardiovasc Dis. 2013 May;23(5):424-31. doi: 10.1016/j.numecd.2011.10.005. Epub 2012 Mar 6.
1531 SOD3 Is Secreted by Adipocytes and Mitigates High-Fat Diet-Induced Obesity, Inflammation, and Insulin Resistance.Antioxid Redox Signal. 2020 Jan 20;32(3):193-212. doi: 10.1089/ars.2018.7628.
1532 Alterations of sorbin and SH3 domain containing 3 (SORBS3) in human skeletal muscle following Roux-en-Y gastric bypass surgery.Clin Epigenetics. 2017 Sep 2;9:96. doi: 10.1186/s13148-017-0396-5. eCollection 2017.
1533 The genetic basis of obesity-associated type 2 diabetes (diabesity) in polygenic mouse models.Mamm Genome. 2014 Oct;25(9-10):401-12. doi: 10.1007/s00335-014-9514-2. Epub 2014 Apr 22.
1534 SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity.J Clin Invest. 2016 Jul 1;126(7):2706-20. doi: 10.1172/JCI84708. Epub 2016 Jun 20.
1535 SOX6 rs7117858 polymorphism is associated with osteoporosis and obesity-related phenotypes.Eur J Clin Invest. 2018 Oct;48(10):e13011. doi: 10.1111/eci.13011. Epub 2018 Aug 16.
1536 Transcription Factor Co-expression Networks of Adipose RNA-Seq Data Reveal Regulatory Mechanisms of Obesity.Curr Genomics. 2018 May;19(4):289-299. doi: 10.2174/1389202918666171005095059.
1537 Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease.J Hepatol. 2008 Nov;49(5):810-20. doi: 10.1016/j.jhep.2008.05.016. Epub 2008 Jun 10.
1538 Intestinal peptide changes after bariatric and minimally invasive surgery: Relation to diabetes remission.Peptides. 2018 Feb;100:114-122. doi: 10.1016/j.peptides.2017.12.010.
1539 Chromosomal architecture and placental expression of the human growth hormone gene family are targeted by pre-pregnancy maternal obesity.Am J Physiol Endocrinol Metab. 2018 Oct 1;315(4):E435-E445. doi: 10.1152/ajpendo.00042.2018. Epub 2018 May 15.
1540 Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.Int J Obes (Lond). 2017 Mar;41(3):390-401. doi: 10.1038/ijo.2016.220. Epub 2016 Dec 5.
1541 Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance.Glycobiology. 2017 Jan;27(2):129-139. doi: 10.1093/glycob/cww098. Epub 2016 Sep 28.
1542 The Inhibitory Effects of Cobalt Protoporphyrin IX and Cannabinoid 2 Receptor Agonists in Type 2 Diabetic Mice.Int J Mol Sci. 2017 Oct 28;18(11):2268. doi: 10.3390/ijms18112268.
1543 STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation.Endocrine. 2017 Jun;56(3):528-537. doi: 10.1007/s12020-017-1297-2. Epub 2017 Apr 12.
1544 DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway.Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12196-12201. doi: 10.1073/pnas.1708744114. Epub 2017 Oct 30.
1545 Macrosomia, obesity, and macrocephaly as first clinical presentation of PHP1b caused by STX16 deletion.Am J Med Genet A. 2016 Sep;170(9):2431-5. doi: 10.1002/ajmg.a.37818. Epub 2016 Jun 23.
1546 Expression of syntaxin 8 in visceral adipose tissue is increased in obese patients with type 2 diabetes and related to markers of insulin resistance and inflammation.Arch Med Res. 2015 Jan;46(1):47-53. doi: 10.1016/j.arcmed.2014.12.003. Epub 2014 Dec 15.
1547 Munc18c in adipose tissue is downregulated in obesity and is associated with insulin.PLoS One. 2013 May 20;8(5):e63937. doi: 10.1371/journal.pone.0063937. Print 2013.
1548 Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications.PLoS One. 2009 Dec 7;4(12):e8100. doi: 10.1371/journal.pone.0008100.
1549 Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans.Oncotarget. 2015 Oct 6;6(30):29818-32. doi: 10.18632/oncotarget.4904.
1550 Effects of Orchidectomy and Testosterone Replacement on Numbers of Kisspeptin-, Neurokinin B-, and Dynorphin A-Immunoreactive Neurones in the Arcuate Nucleus of the Hypothalamus in Obese and Diabetic Rats.J Neuroendocrinol. 2017 Feb;29(2). doi: 10.1111/jne.12453.
1551 Control of adipose tissue inflammation through TRB1.Diabetes. 2010 Aug;59(8):1991-2000. doi: 10.2337/db09-1537. Epub 2010 Jun 3.
1552 Integrated analysis of the gene expression profile and DNA methylation profile of obese patients with type 2 diabetes.Mol Med Rep. 2018 Jun;17(6):7636-7644. doi: 10.3892/mmr.2018.8804. Epub 2018 Mar 28.
1553 RabGAPs in skeletal muscle function and exercise.J Mol Endocrinol. 2020 Jan;64(1):R1-R19. doi: 10.1530/JME-19-0143.
1554 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.PLoS Genet. 2009 Jun;5(6):e1000508. doi: 10.1371/journal.pgen.1000508. Epub 2009 Jun 26.
1555 Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway.Mol Metab. 2019 Oct;28:48-57. doi: 10.1016/j.molmet.2019.07.004. Epub 2019 Jul 5.
1556 Socioeconomic inequality in childhood obesity and its determinants: a Blinder-Oaxaca decomposition.J Pediatr (Rio J). 2018 Mar-Apr;94(2):131-139. doi: 10.1016/j.jped.2017.03.009. Epub 2017 Aug 18.
1557 Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans.Diabetologia. 2018 May;61(5):1167-1179. doi: 10.1007/s00125-018-4571-9. Epub 2018 Feb 24.
1558 The TCN2 variant of rs9606756 [Ile23Val] acts as risk loci for obesity-related traits and mediates by interacting with Apo-A1.Obesity (Silver Spring). 2017 Jun;25(6):1098-1108. doi: 10.1002/oby.21826. Epub 2017 Apr 17.
1559 Energy and metabolic pathways in trefoil factor family member 2 (Tff2) KO mice beyond the protection from high-fat diet-induced obesity.Life Sci. 2018 Dec 15;215:190-197. doi: 10.1016/j.lfs.2018.11.006. Epub 2018 Nov 7.
1560 THADA Regulates the Organismal Balance between Energy Storage and Heat Production.Dev Cell. 2017 Apr 10;41(1):72-81.e6. doi: 10.1016/j.devcel.2017.03.016.
1561 Elevated Thrombospondin 2 Contributes to Delayed Wound Healing in Diabetes.Diabetes. 2019 Oct;68(10):2016-2023. doi: 10.2337/db18-1001. Epub 2019 Aug 7.
1562 Carboxyl-Terminal Modulator Protein Ameliorates Pathological Cardiac Hypertrophy by Suppressing the Protein Kinase B Signaling Pathway.J Am Heart Assoc. 2018 Jun 26;7(13):e008654. doi: 10.1161/JAHA.118.008654.
1563 Identification of diabetes- and obesity-associated proteomic changes in human spermatozoa by difference gel electrophoresis.Reprod Biomed Online. 2009 Nov;19(5):660-70. doi: 10.1016/j.rbmo.2009.07.001.
1564 The serum level of a novel lipogenic protein Spot 14 was reduced in metabolic syndrome.PLoS One. 2019 Feb 14;14(2):e0212341. doi: 10.1371/journal.pone.0212341. eCollection 2019.
1565 A novel gene THSD7A is associated with obesity.Int J Obes (Lond). 2015 Nov;39(11):1662-5. doi: 10.1038/ijo.2015.144. Epub 2015 Aug 4.
1566 Loss of TIGAR Induces Oxidative Stress and Meiotic Defects in Oocytes from Obese Mice.Mol Cell Proteomics. 2018 Jul;17(7):1354-1364. doi: 10.1074/mcp.RA118.000620. Epub 2018 May 18.
1567 Absence of Tissue Inhibitor of Metalloproteinase-4 (TIMP4) ameliorates high fat diet-induced obesity in mice due to defective lipid absorption.Sci Rep. 2017 Jul 24;7(1):6210. doi: 10.1038/s41598-017-05951-4.
1568 Increased Expression of the Innate Immune Receptor TLR10 in Obesity and Type-2 Diabetes: Association with ROS-Mediated Oxidative Stress.Cell Physiol Biochem. 2018;45(2):572-590. doi: 10.1159/000487034. Epub 2018 Jan 30.
1569 Trans-anethole ameliorates obesity via induction of browning in white adipocytes and activation of brown adipocytes.Biochimie. 2018 Aug;151:1-13. doi: 10.1016/j.biochi.2018.05.009. Epub 2018 May 24.
1570 A follow-up study for left ventricular mass on chromosome 12p11 identifies potential candidate genes.BMC Med Genet. 2011 Jul 26;12:100. doi: 10.1186/1471-2350-12-100.
1571 The involvement of 4-1BB/4-1BBL signaling in glial cell-mediated hypothalamic inflammation in obesity.FEBS Open Bio. 2018 Apr 19;8(5):843-853. doi: 10.1002/2211-5463.12426. eCollection 2018 May.
1572 Effects of X-chromosome Tenomodulin Genetic Variants on Obesity in a Children's Cohort and Implications of the Gene in Adipocyte Metabolism.Sci Rep. 2019 Mar 8;9(1):3979. doi: 10.1038/s41598-019-40482-0.
1573 Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis.Cell Metab. 2011 Aug 3;14(2):208-18. doi: 10.1016/j.cmet.2011.06.007.
1574 Mutations that impair interaction properties of TRIM32 associated with limb-girdle muscular dystrophy 2H.Hum Mutat. 2008 Feb;29(2):240-7. doi: 10.1002/humu.20633.
1575 Electroacupuncture Reduces Weight in Diet-Induced Obese Rats via Hypothalamic Tsc1 Promoter Demethylation and Inhibition of the Activity of mTORC1 Signaling Pathway.Evid Based Complement Alternat Med. 2018 Apr 26;2018:3039783. doi: 10.1155/2018/3039783. eCollection 2018.
1576 Low expression of the GILZ may contribute to adipose inflammation and altered adipokine production in human obesity.J Lipid Res. 2016 Jul;57(7):1256-63. doi: 10.1194/jlr.M067728. Epub 2016 May 13.
1577 Obesity and diabetes genetic variants associated with gestational weight gain.Am J Obstet Gynecol. 2010 Sep;203(3):283.e1-17. doi: 10.1016/j.ajog.2010.06.069.
1578 Increased fibrosis: A novel means by which GH influences white adipose tissue function.Growth Horm IGF Res. 2018 Apr;39:45-53. doi: 10.1016/j.ghir.2017.12.010. Epub 2017 Dec 20.