Details of Disease

General Information of Disease (ID: DIS4ZSCO)

• Disease Name: Alcohol dependence
• Synonyms: aerodigestive tract cancer, squamous cell, alcohol-related, protection against; alcohol dependence, protection against; alcohol dependence, susceptibility to; alcohol dependence; alcoholism
• Disease Class: 6C40: Substance abuse
• Definition: Physical and psychological dependence on alcohol.
• Disease Hierarchy:
  DIS3K4KK: Alcohol-related disorders
  DISDRAAR: Substance dependence
  DIS9IXRC: Drug dependence
  DIS4ZSCO: Alcohol dependence
• ICD Code:
  ICD-11: ICD-11: 6C40.2
  ICD-10: ICD-10: F10.2
  ICD-9: ICD-9: 303
  Expand ICD-11: '6C40
  Expand ICD-10: 'F10; 'F10.7; 'F10.8; 'F10.9
  Expand ICD-9: 303
• Disease Identifiers:
  MONDO ID: MONDO_0007079
  MESH ID: D000437
  UMLS CUI: C0001973
  OMIM ID: 103780
  MedGen ID: 1801
  HPO ID: HP:0030955
  SNOMED CT ID: 284591009

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 16 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Acamprosate	DMO381I	Approved	Small molecular drug	[1]
Calcium carbimide	DM3W15N	Approved	Small molecular drug	[2]
Chloral hydrate	DMEOSTQ	Approved	Small molecular drug	[2]
Dihydroergocristine	DM5SQ1G	Approved	Small molecular drug	[3]
Disulfiram	DMCL2OK	Approved	Small molecular drug	[2]
Ibudilast	DM4LSPN	Approved	Small molecular drug	[4]
MOXONIDINE	DMGFB0E	Approved	Small molecular drug	[5]
Naltrexone	DMUL45H	Approved	Small molecular drug	[2]
Ondansetron	DMOTQ1I	Approved	Small molecular drug	[6]
Piracetam	DM5BXH9	Approved	Small molecular drug	[7]
Quetiapine	DM1N62C	Approved	Small molecular drug	[8]
Tiapride	DMN6CAG	Approved	Small molecular drug	[2]
Topiramate	DM82Z30	Approved	Small molecular drug	[9]
Valproate	DMCFE9I	Approved	Small molecular drug	[10]
Vigabatrin	DMYT0OG	Approved	Small molecular drug	[11]
Zonisamide	DM0DTF7	Approved	Small molecular drug	[12]

This Disease is Treated as An Indication in 17 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Amitifadine	DMS1X67	Phase 3	Small molecular drug	[4]
Arbaclofen placarbil	DMO628K	Phase 3	Small molecular drug	[4]
CORT-125134	DMBS3UG	Phase 3	NA	[4]
LY-686017	DM7WORZ	Phase 3	Small molecular drug	[13]
AD04	DMLV9GS	Phase 2	NA	[4]
ALKS33	DMF3QN1	Phase 2	Small molecular drug	[14]
Gabapentin enacarbil	DMJY2TM	Phase 2	Small molecular drug	[4]
GET 73	DMVYJT6	Phase 2	NA	[15]
GSK561679	DMEVARK	Phase 2	Small molecular drug	[16]
JNJ-39220675	DM0WY3H	Phase 2	Small molecular drug	[17]
LY-2456302	DMLTSDC	Phase 2	Small molecular drug	[4]
Odelepran	DMK0MJP	Phase 2	Small molecular drug	[18]
OPNT002	DM942SD	Phase 2	NA	[4]
Puerarin	DMJIMXH	Phase 2	Small molecular drug	[19]
Desoxypeganine	DMTR7EH	Phase 1	Small molecular drug	[20]
GSK1144814	DMK3S9J	Phase 1	NA	[21]
KRL-901	DMJI0OU	Phase 1	NA	[22]

This Disease is Treated as An Indication in 5 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Melperone	DMSPDZU	Withdrawn from market	Small molecular drug	[2]
MT-7716	DMO8DSA	Discontinued in Phase 1	NA	[23]
AMPEROZIDE	DMDAMBW	Terminated	Small molecular drug	[26]
CGS-17867A	DMMZJY3	Terminated	Small molecular drug	[27]
SC-112	DME2UBA	Terminated	NA	[28]

This Disease is Treated as An Indication in 2 Preclinical Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
AEZS-123	DMYIK5D	Preclinical	NA	[24]
SoRI-9409	DMSNX4O	Preclinical	Small molecular drug	[25]

This Disease is Treated as An Indication in 4 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
CVT-10216	DMDH6PJ	Investigative	Small molecular drug	[29]
Nalmefene prodrug	DMMHKXH	Investigative	NA	[30]
Naltrexone prodrug	DMKYR0R	Investigative	NA	[30]
NT-69-L	DMUHZ2V	Investigative	NA	[31]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 149 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
CFP	TTLA0VS	Limited	Biomarker	[32]
CYP2A6	TTAQ6ZW	Limited	Genetic Variation	[33]
F9	TTFEZ5Q	Limited	Biomarker	[34]
FTO	TTFW3BT	Limited	Genetic Variation	[35]
GRIN2A	TTKJEMQ	Limited	Biomarker	[36]
SCN11A	TTN9VTF	Limited	Altered Expression	[37]
SLC19A3	TT9BTWM	Limited	Genetic Variation	[38]
SMPD1	TTJTM88	Limited	Biomarker	[39]
TDO2	TTXNCBV	Limited	Genetic Variation	[40]
ABAT	TTT2LD9	moderate	Genetic Variation	[41]
CACNA1C	TTZIFHC	moderate	Altered Expression	[42]
CHM	TTOA18V	moderate	Genetic Variation	[43]
CHRM5	TTH18TF	moderate	Genetic Variation	[44]
COL6A3	TT5WCAH	moderate	Biomarker	[45]
DAGLA	TTRQ6UD	moderate	Biomarker	[46]
ESRRG	TT9ZRHB	moderate	Genetic Variation	[47]
GLP1R	TTVIMDE	moderate	Biomarker	[48]
GM2A	TTGOFW6	moderate	Genetic Variation	[49]
GRIN2C	TT1M8OW	moderate	Genetic Variation	[50]
GRK5	TTTCXO0	moderate	Genetic Variation	[51]
HCRTR1	TT60Q8D	moderate	Biomarker	[52]
HTR1E	TTCPG9S	moderate	Genetic Variation	[53]
HTT	TTIWZ0O	moderate	Biomarker	[54]
KCNK3	TTGR91N	moderate	Altered Expression	[55]
KCNN3	TT9JH25	moderate	Altered Expression	[56]
LYZ	TTAOZBW	moderate	Genetic Variation	[57]
MBNL2	TTH9OLG	moderate	Genetic Variation	[58]
MC4R	TTD0CIQ	moderate	Biomarker	[59]
NPY1R	TTRK9JT	moderate	Biomarker	[60]
OXTR	TTSCIUP	moderate	Biomarker	[61]
PGC	TT7K6AD	moderate	Biomarker	[62]
PNPLA3	TTEUAEH	moderate	Genetic Variation	[63]
RXRB	TTKLV96	moderate	Genetic Variation	[64]
SLC1A3	TT8WRDA	moderate	Biomarker	[65]
SORT1	TTRX9AV	moderate	Altered Expression	[66]
THRA	TTTSEPU	moderate	Biomarker	[67]
TPH2	TT3KLDP	moderate	Biomarker	[68]
ADCY1	TTV1ZSQ	Strong	Genetic Variation	[69]
ADCY5	TTN64VU	Strong	Biomarker	[70]
ADH1A	TT5AHZ0	Strong	Biomarker	[71]
ADH7	TT3LE7P	Strong	Genetic Variation	[72]
ADRA2A	TTWG9A4	Strong	Biomarker	[73]
AKR1C3	TT5ZWB6	Strong	Genetic Variation	[74]
ALK	TTPMQSO	Strong	Biomarker	[75]
ARSA	TTYQANR	Strong	Biomarker	[76]
CAT	TTPS279	Strong	Biomarker	[77]
CDH11	TTRGWZC	Strong	Biomarker	[78]
CDH5	TTXLCFO	Strong	Biomarker	[78]
CFTR	TTRLZHP	Strong	Biomarker	[79]
CHRNA4	TT4H1MQ	Strong	Altered Expression	[80]
CHRNA5	TTH2QRX	Strong	Genetic Variation	[81]
CHRNB4	TTTVAFQ	Strong	Genetic Variation	[82]
CNR1	TT6OEDT	Strong	Genetic Variation	[83]
CNR2	TTMSFAW	Strong	Biomarker	[84]
CREB1	TTH4AN3	Strong	Biomarker	[85]
CRH	TTA7YIZ	Strong	Biomarker	[86]
CRHBP	TT3PKZE	Strong	Biomarker	[87]
CRHR1	TT7EFHR	Strong	Genetic Variation	[88]
CYP2B6	TTMH124	Strong	Biomarker	[89]
DKK2	TTST5KX	Strong	Genetic Variation	[90]
DPYSL2	TTZCW3T	Strong	Genetic Variation	[91]
EP300	TTGH73N	Strong	Biomarker	[92]
EPHA8	TTHZ2LW	Strong	Biomarker	[93]
FABP2	TTS4YLO	Strong	Biomarker	[94]
FKBP5	TT0J5KQ	Strong	Biomarker	[95]
FOLR1	TTVC37M	Strong	Biomarker	[96]
FSHB	TT13GFV	Strong	Biomarker	[97]
FYN	TT2B9KF	Strong	Genetic Variation	[98]
GABRA5	TTNZPQ1	Strong	Biomarker	[99]
GABRG2	TT06RH5	Strong	Genetic Variation	[100]
GABRG3	TTEX6LM	Strong	Genetic Variation	[101]
GABRR1	TT6XFEU	Strong	Biomarker	[102]
GABRR2	TTQMXLS	Strong	Biomarker	[102]
GAD1	TTKGEP3	Strong	Biomarker	[103]
GAL	TTXZAJ5	Strong	Altered Expression	[104]
GAP43	TTSGLN5	Strong	Biomarker	[105]
GAPDH	TTUGSWA	Strong	Biomarker	[106]
GFAP	TTI6FFX	Strong	Biomarker	[107]
GGH	TTZJRL0	Strong	Biomarker	[108]
GGT1	TTZVT7O	Strong	Biomarker	[109]
GH1	TTT3YKH	Strong	Biomarker	[110]
GHSR	TTWDC17	Strong	Genetic Variation	[111]
GLI2	TT045OH	Strong	Altered Expression	[112]
GLUL	TTURQ2G	Strong	Genetic Variation	[113]
GRIK1	TT0MYE2	Strong	Genetic Variation	[50]
GRIN1	TTLD29N	Strong	Biomarker	[114]
GRM1	TTVBPDM	Strong	Biomarker	[115]
GRM2	TTXJ47W	Strong	Biomarker	[116]
GRM3	TT8A9EF	Strong	Genetic Variation	[117]
GRM7	TT0I76D	Strong	Biomarker	[118]
GRM8	TT0IFKL	Strong	Biomarker	[119]
GSS	TTVEWR4	Strong	Genetic Variation	[120]
HAMP	TTRV5YJ	Strong	Biomarker	[121]
HDAC2	TTSHTOI	Strong	Biomarker	[122]
HMGB1	TTWQYB7	Strong	Biomarker	[123]
HNMT	TT2B6EV	Strong	Biomarker	[124]
HTR3B	TTR6K75	Strong	Biomarker	[125]
HTR7	TTO9X1H	Strong	Biomarker	[126]
IL17A	TTG0MT6	Strong	Biomarker	[127]
IL1RN	TT6GSR3	Strong	Biomarker	[128]
KCNJ6	TTTIBVP	Strong	Biomarker	[129]
LEP	TTBJEZ5	Strong	Biomarker	[130]
MAOB	TTGP7BY	Strong	Altered Expression	[131]
MAP3K4	TT1RSX7	Strong	Genetic Variation	[132]
MBP	TT2RY5P	Strong	Biomarker	[133]
MMP2	TTLM12X	Strong	Biomarker	[134]
MOBP	TTYUK4F	Strong	Biomarker	[133]
MOG	TTQAFX5	Strong	Biomarker	[133]
MTHFR	TTQWOU1	Strong	Genetic Variation	[135]
NCAM1	TTVXPHT	Strong	Biomarker	[114]
NFKB1	TTUIZKC	Strong	Genetic Variation	[136]
NMUR2	TT2L6C5	Strong	Biomarker	[137]
NPSR1	TTV1C0Z	Strong	Biomarker	[138]
NPY	TT64REZ	Strong	Biomarker	[139]
NPY2R	TTJ6WK9	Strong	Genetic Variation	[140]
NPY5R	TTY6EWA	Strong	Biomarker	[60]
NQO2	TTJLP0R	Strong	Biomarker	[141]
NR4A2	TT9HKN3	Strong	Biomarker	[142]
NTRK2	TTKN7QR	Strong	Genetic Variation	[143]
PDE10A	TTJW4LU	Strong	Biomarker	[144]
PDE4B	TTVIAT9	Strong	Biomarker	[145]
PTK2B	TTTEFBV	Strong	Genetic Variation	[93]
PTP4A1	TTA8GFO	Strong	Genetic Variation	[146]
RACK1	TTJ10AL	Strong	Biomarker	[147]
RARA	TTW38KT	Strong	Genetic Variation	[148]
REN	TTB2MXP	Strong	Biomarker	[149]
RGS4	TTGTKX9	Strong	Biomarker	[150]
SEMA3A	TTVKD3S	Strong	Biomarker	[47]
SIGMAR1	TT5TPI6	Strong	Biomarker	[151]
SLC18A2	TTNZRI3	Strong	Biomarker	[152]
SLC1A2	TT2F078	Strong	Biomarker	[153]
SLC29A1	TTLXAKE	Strong	Biomarker	[154]
SLC46A1	TTY8Z2E	Strong	Biomarker	[155]
SLC6A1	TTPRKM0	Strong	Genetic Variation	[156]
SLCO3A1	TT5CE6L	Strong	Biomarker	[157]
SNCA	TT08OSU	Strong	Biomarker	[158]
SRD5A1	TTTU72V	Strong	Genetic Variation	[74]
SRD5A2	TTT02K8	Strong	Biomarker	[159]
TACR1	TTZPO1L	Strong	Biomarker	[160]
TACR3	TTBPGLU	Strong	Genetic Variation	[161]
TESK2	TTRMD8U	Strong	Genetic Variation	[162]
TF	TT8WXAV	Strong	Biomarker	[163]
TIPARP	TT2FRAN	Strong	Biomarker	[162]
TKT	TT04R7I	Strong	Biomarker	[133]
TPH1	TTZSJHV	Strong	Genetic Variation	[164]
TRH	TT2Z39D	Strong	Biomarker	[165]
VWF	TT3SZBT	Strong	Biomarker	[166]
XRCC5	TTCB9KW	Strong	Biomarker	[167]
AVPR1B	TTL9MHW	Definitive	Biomarker	[168]

This Disease Is Related to 3 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
SLC17A6	DT5LHCR	moderate	Genetic Variation	[169]
SLC39A8	DTLPQGT	moderate	Genetic Variation	[35]
SLC6A6	DTHWCVA	Strong	Genetic Variation	[132]

This Disease Is Related to 14 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
PER1	DE9HF0I	Limited	Genetic Variation	[170]
ALDH1B1	DEXI4UQ	moderate	Genetic Variation	[171]
DHRS9	DEGTU5I	moderate	Genetic Variation	[172]
FAAH	DEUM1EX	moderate	Genetic Variation	[173]
THOP1	DE95LJC	moderate	Biomarker	[174]
ABO	DESIA7R	Strong	Biomarker	[175]
ADH6	DE017IC	Strong	Genetic Variation	[176]
AKR1A1	DED2FW3	Strong	Genetic Variation	[177]
AKR1C4	DEAJN47	Strong	Biomarker	[172]
ALDH1A1	DE2JP1Y	Strong	Genetic Variation	[143]
CYP2A13	DEXZA9U	Strong	Biomarker	[71]
EPHX1	DELB4KP	Strong	Biomarker	[178]
NAT1	DE7OAB3	Strong	Genetic Variation	[179]
SAT1	DEMWO83	Strong	Genetic Variation	[180]

This Disease Is Related to 174 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CCDC6	OTXRQDYG	Limited	Biomarker	[34]
GABRB1	OT4L2SSB	Limited	Biomarker	[181]
GABRB3	OT80C3D4	Limited	Biomarker	[114]
HDGFL3	OTNN7WYH	Limited	Biomarker	[37]
MPDZ	OT9WY1QM	Limited	Biomarker	[182]
PER2	OTU2B1DJ	Limited	Biomarker	[183]
PLCD3	OTB22A4J	Limited	Altered Expression	[184]
PNOC	OTJEAADN	Limited	Genetic Variation	[185]
PRDM2	OT8L7CGX	Limited	Biomarker	[186]
SMARCA1	OT0Y6PTU	Limited	Biomarker	[187]
ABLIM1	OTHXEK3E	moderate	Genetic Variation	[162]
ADCY9	OT1IZT5K	moderate	Genetic Variation	[188]
AP2B1	OTL6LZJ4	moderate	Biomarker	[189]
AUTS2	OTAEXHSC	moderate	Genetic Variation	[190]
BTBD8	OT3A3RD7	moderate	Genetic Variation	[191]
CCSER1	OTVLD4J3	moderate	Genetic Variation	[51]
CHRNB1	OTTJXD24	moderate	Genetic Variation	[192]
CNIH3	OTNLZ2QS	moderate	Genetic Variation	[193]
CSRNP3	OTOANEHZ	moderate	Genetic Variation	[51]
CTNNA2	OTJ8G92T	moderate	Genetic Variation	[194]
DBI	OT884QY9	moderate	Genetic Variation	[195]
DMTN	OTDTKPBW	moderate	Genetic Variation	[196]
EBPL	OT59J1GY	moderate	Genetic Variation	[197]
EFHC2	OTI459M8	moderate	Biomarker	[198]
EFHD2	OTM9VMN3	moderate	Biomarker	[198]
EYS	OT0NBPL5	moderate	Genetic Variation	[146]
FAM162A	OT882DND	moderate	Genetic Variation	[51]
FSTL5	OT18C29S	moderate	Genetic Variation	[51]
GCKR	OTSIWXGG	moderate	Genetic Variation	[35]
GDAP1	OTQE1O25	moderate	Biomarker	[199]
HARS1	OTHOEOTS	moderate	Genetic Variation	[200]
HERC5	OTZ5PR39	moderate	Biomarker	[188]
HEY2	OTU4J3ZI	moderate	Posttranslational Modification	[201]
HGS	OTCYYCAC	moderate	Genetic Variation	[200]
HHEX	OTLIUVYX	moderate	Biomarker	[202]
IGSF22	OTQRM8GQ	moderate	Genetic Variation	[51]
IGSF9B	OTNOMYYQ	moderate	Genetic Variation	[47]
IMPA1	OTBUVW1Z	moderate	Biomarker	[203]
KCNK13	OTMOT2KX	moderate	Biomarker	[204]
KIAA0040	OT27EBY3	moderate	Biomarker	[126]
KLF12	OTVH4KD4	moderate	Genetic Variation	[47]
MARK1	OTP7KL47	moderate	Biomarker	[205]
MICB	OTS2DVDW	moderate	Genetic Variation	[35]
MRGPRF	OT74OZ2Z	moderate	Biomarker	[206]
MYT1	OTC3660I	moderate	Biomarker	[207]
NCALD	OTJZ8UEL	moderate	Genetic Variation	[47]
NLN	OTFRITPU	moderate	Biomarker	[208]
NPDC1	OT788NC8	moderate	Biomarker	[188]
NPL	OTA7P0TO	moderate	Biomarker	[209]
NRGN	OTVGE10W	moderate	Biomarker	[210]
NRXN1	OTJN1JQA	moderate	Genetic Variation	[211]
OPA3	OT6NDC1M	moderate	Biomarker	[126]
OPN4	OT1LZ7TS	moderate	Biomarker	[208]
OR2AG1	OTEITRP4	moderate	Biomarker	[212]
PARP9	OT7K4494	moderate	Genetic Variation	[213]
PCDH19	OTSOW3MV	moderate	Biomarker	[78]
PHEX	OTG7N3J7	moderate	Biomarker	[203]
PLGRKT	OT5ITHAW	moderate	Genetic Variation	[51]
PPP1R16B	OTZJFX5C	moderate	Genetic Variation	[214]
PRSS21	OT8ZYC7G	moderate	Genetic Variation	[215]
RAB40B	OTCA9ZF5	moderate	Genetic Variation	[148]
RBFOX2	OTXY1WVH	moderate	Biomarker	[206]
RHBDL2	OTJPJ8N6	moderate	Genetic Variation	[47]
SALL3	OTJ2LZKQ	moderate	Biomarker	[216]
SERINC2	OTZ039U0	moderate	Genetic Variation	[217]
SPACA9	OTVRFX49	moderate	Biomarker	[218]
SRSF5	OTC5WP98	moderate	Genetic Variation	[200]
STAG3	OTEV0AOD	moderate	Genetic Variation	[47]
SYN2	OTK0DEGH	moderate	Genetic Variation	[219]
ACE	OTDF1964	Strong	Biomarker	[220]
ADAMTSL1	OTBNYF3F	Strong	Genetic Variation	[120]
ADCY7	OTAWMGP3	Strong	Biomarker	[221]
AGBL4	OTOX2H61	Strong	Genetic Variation	[194]
AGO1	OTD3R434	Strong	Biomarker	[222]
AGO2	OT4JY32Q	Strong	Genetic Variation	[222]
ALLC	OTZE4XV7	Strong	Genetic Variation	[223]
ANAPC1	OT2YY35L	Strong	Biomarker	[157]
ANKRD7	OTBW7AR4	Strong	Biomarker	[224]
ANKS1B	OT26DGM9	Strong	Genetic Variation	[194]
ARC	OTN2QQPG	Strong	Biomarker	[225]
ARFGEF2	OTM3CQZT	Strong	Genetic Variation	[144]
ARL15	OT00YSWZ	Strong	Genetic Variation	[226]
ASTN1	OT23FQIB	Strong	Biomarker	[227]
BAG3	OTVXYUDQ	Strong	Biomarker	[166]
BHMT	OTYB6PXZ	Strong	Biomarker	[228]
BRAP	OTB7BAFQ	Strong	Genetic Variation	[229]
C1D	OTI9PMN1	Strong	Genetic Variation	[230]
CAMK2A	OTJGX19T	Strong	Biomarker	[231]
CARS1	OTOUZF6O	Strong	Biomarker	[232]
CARTPT	OTTE4V9S	Strong	Biomarker	[233]
CDH10	OTK3D5WP	Strong	Biomarker	[78]
CDH13	OTD2CYM5	Strong	Biomarker	[234]
CDH15	OTJ1TO02	Strong	Biomarker	[78]
CDH18	OTC06P9H	Strong	Biomarker	[78]
CDH8	OTS3SRZ6	Strong	Biomarker	[78]
CDH9	OTV9N5XK	Strong	Biomarker	[78]
CDK20	OTOLNN68	Strong	Biomarker	[145]
CHRNA3	OTCZQY1U	Strong	Genetic Variation	[235]
CHRNB3	OTE5XENW	Strong	Genetic Variation	[236]
CLOCK	OTNEOJY7	Strong	Biomarker	[237]
CNTN4	OTULXVE0	Strong	Biomarker	[144]
CNTN6	OTXVGVOR	Strong	Biomarker	[144]
CNTNAP2	OT48T2ZP	Strong	Genetic Variation	[238]
CPNE5	OTU882I6	Strong	Genetic Variation	[239]
CYTL1	OTLYUPUY	Strong	Biomarker	[224]
DCLRE1C	OTW3KB1I	Strong	Biomarker	[240]
DDX53	OTHK3EGZ	Strong	Genetic Variation	[241]
DNASE1L3	OTEUIMC2	Strong	Biomarker	[242]
DSCAML1	OT7QURQT	Strong	Biomarker	[243]
ECHS1	OTS0593S	Strong	Biomarker	[228]
GABRG1	OT1NGUYY	Strong	Biomarker	[244]
GALR3	OTXU6PKO	Strong	Biomarker	[245]
GEMIN4	OTX7402E	Strong	Biomarker	[222]
GPHN	OTAKK1SV	Strong	Biomarker	[246]
HERPUD1	OT9EROL6	Strong	Biomarker	[201]
HLA-DRA	OT7KZMP2	Strong	Genetic Variation	[247]
IPO11	OTG19WN0	Strong	Biomarker	[248]
KANK1	OT2E7A6W	Strong	Biomarker	[157]
KLF11	OTKVQDJD	Strong	Biomarker	[106]
KPNA3	OTLI3TM2	Strong	Genetic Variation	[249]
LHB	OT5GBOVJ	Strong	Biomarker	[97]
LHPP	OT9AGAIJ	Strong	Biomarker	[250]
LILRA1	OTZ4NA7Q	Strong	Genetic Variation	[162]
LRP8	OTZ71YV2	Strong	Genetic Variation	[251]
MEF2C	OTZGF1Y5	Strong	Genetic Variation	[252]
MREG	OT0LUIRG	Strong	Biomarker	[126]
NAP1L4	OTUEG3QY	Strong	Biomarker	[232]
NCOA6	OTOMIGTV	Strong	Genetic Variation	[120]
NKAIN1	OT7IEGAZ	Strong	Biomarker	[217]
NKAIN2	OTI4H30Z	Strong	Biomarker	[243]
NLGN4X	OTDJGBK8	Strong	Genetic Variation	[253]
NPS	OTEG25A2	Strong	Biomarker	[138]
NRDC	OTWBBCXO	Strong	Biomarker	[126]
NRXN3	OTJ0I7HJ	Strong	Biomarker	[254]
NSG1	OTRIMA50	Strong	Genetic Variation	[255]
NTS	OTPGDNQS	Strong	Biomarker	[256]
OSBPL5	OTI1UJXT	Strong	Biomarker	[232]
OXT	OT48M72Z	Strong	Genetic Variation	[257]
PCDH10	OT2GIT0E	Strong	Biomarker	[78]
PCDH12	OT2VANLI	Strong	Biomarker	[78]
PECR	OT5MS8EM	Strong	Biomarker	[126]
PER3	OTVKYVJA	Strong	Genetic Variation	[258]
PHF3	OTNOYLG9	Strong	Biomarker	[146]
PHLDA2	OTMV9DPP	Strong	Biomarker	[232]
PIK3R1	OT5BZ1J9	Strong	Biomarker	[259]
PLCL2	OTK5FDF6	Strong	Genetic Variation	[132]
PPP1R1B	OTSIJMQ9	Strong	Biomarker	[260]
RASGRF2	OT67DAGF	Strong	Biomarker	[261]
RFC1	OT3L5PK3	Strong	Biomarker	[96]
RFX4	OTYFRHPA	Strong	Biomarker	[162]
RHOG	OTJ7J1WA	Strong	Genetic Variation	[120]
SAGE1	OT4H6FFA	Strong	Biomarker	[262]
SDHAF3	OTD2JO6B	Strong	Biomarker	[263]
SEMA5A	OTUOIOJV	Strong	Biomarker	[264]
SETD5	OTRPAVEO	Strong	Genetic Variation	[255]
SGCE	OT9F17JB	Strong	Genetic Variation	[265]
SHBG	OTPWU5IW	Strong	Biomarker	[266]
SLC22A18	OT9C3KR4	Strong	Biomarker	[232]
SNRNP70	OTP52YZ3	Strong	Biomarker	[267]
SPG21	OTMKJSYS	Strong	Biomarker	[218]
ST18	OTPRIMTA	Strong	Biomarker	[166]
STK40	OT4R325X	Strong	Genetic Variation	[268]
STON2	OT01JHHE	Strong	Biomarker	[162]
TAC1	OTM842YW	Strong	Biomarker	[269]
TAGLN3	OTJBP3VJ	Strong	Biomarker	[270]
TAS2R16	OT67HLNS	Strong	Biomarker	[271]
TBX19	OTXEMR2U	Strong	Biomarker	[145]
TFAP2B	OTR1T8E9	Strong	Genetic Variation	[189]
THEMIS	OTXODBXJ	Strong	Biomarker	[162]
THSD7B	OTMDDIPT	Strong	Biomarker	[264]
TMEM161B	OTHVICQS	Strong	Genetic Variation	[252]
TMEM260	OTICII2L	Strong	Genetic Variation	[132]
TRPC4AP	OTNJ9IFS	Strong	Genetic Variation	[120]
TTC12	OTDB24YV	Strong	Biomarker	[110]

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