General Information of Drug (ID: DM0DIEZ)

Drug Name
UNI-rhIL-11
Synonyms Recombinant human interleukin 11 (thrombocytopenia), Uni-Bio Science Group; RhIL-11 (thrombocytopenia), Uni-Bio Science Group
Indication
Disease Entry ICD 11 Status REF
Thrombocytopenia 3B64 Phase 3 [1]
Cross-matching ID
TTD ID
D0E2YL

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin 11 receptor alpha (IL11RA) TTZPLJS I11RA_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

ICD Disease Classification 03 Disease of the blood or blood-forming organs
Disease Class ICD-11: 3B64 Thrombocytopenia
The Studied Tissue Whole blood
The Studied Disease Thrombocytopenia [ICD-11:3B64]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin 11 receptor alpha (IL11RA) DTT IL11RA 1.95E-01 0.44 0.53
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01663441) A Phase Study of Genetically Modified Recombinant Human Interleukin-11. U.S. National Institutes of Health.
2 Clinical study of rhIL-11 for prevention and treatment of chemotherapy-induced thrombocytopenia. Ai Zheng. 2002 Aug;21(8):892-5.