Details of the Drug

General Information of Drug (ID: DM4JG0B)

Drug Name

DA-3607

Synonyms

Ad-stTRAIL; TRAIL adenoviral gene therapy (cancer), Dong-A

Indication

Disease Entry	ICD 11	Status	REF
Brain cancer	2A00	Phase 1	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
TNF related apoptosis inducing ligand (TNFSF10)	TTA5MS9	TNF10_HUMAN	Binder	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Brain cancer

ICD Disease Classification

2A00

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
TNF related apoptosis inducing ligand (TNFSF10)	DTT	TNFSF10	4.40E-01	-0.16	-0.18

Molecular Expression Atlas (MEA)

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026657)
2	Cancer gene therapy using a novel secretable trimeric TRAIL. Gene Ther. 2006 Feb;13(4):330-8.