Details of the Drug

General Information of Drug (ID: DM5IUN8)

Drug Name

12B9m

Indication

Disease Entry	ICD 11	Status	REF
Anaemia	3A90	Preclinical	[1]
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Drug Type

Antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Anaemia

ICD Disease Classification

3A90

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Hepcidin (HAMP)	DTT	HAMP	5.37E-01	0.18	0.47

Molecular Expression Atlas (MEA)

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References

1	Targeting iron metabolism in drug discovery and delivery. Nat Rev Drug Discov. 2017 Jun;16(6):400-423.
2	Pharmacokinetics of anti-hepcidin monoclonal antibody Ab 12B9m and hepcidin in cynomolgus monkeys. AAPS J. 2010 Dec;12(4):646-57.