Details of the Drug

General Information of Drug (ID: DMDSVRP)

Drug Name
DV-1179
Indication
Disease Entry ICD 11 Status REF
Autoimmune disease 4A40-4A45 Phase 1 [1]
Systemic lupus erythematosus 4A40.0 Discontinued in Phase 1 [2]
Cross-matching ID
TTD ID
D00CGX
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Toll-like receptor 7 (TLR7) TTRJ1K4 TLR7_HUMAN Modulator [3]
Toll-like receptor 9 (TLR9) TTSHG0T TLR9_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Autoimmune disease
ICD Disease Classification 4A40-4A45
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Toll-like receptor 7 (TLR7) DTT TLR7 3.32E-25 0.44 0.88
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035150)
3 Company report (Dynavax)