Details of the Drug

General Information of Drug (ID: DMGZ3DR)

Drug Name
NT-3
Synonyms Neurotrophin-3; NT-3, Amgen-Regeneron Partners; NT-3, Amgen/ Regeneron; Neurotrophin-3, Amgen-Regeneron Partners; Neurotrophin-3, Amgen/ Regeneron
Indication
Disease Entry ICD 11 Status REF
Constipation DD91.1 Discontinued in Phase 2 [1]
Cross-matching ID
TTD ID
D00YUB

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neurotrophin-3 (NTF3) TTZHKV9 NTF3_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Constipation
ICD Disease Classification DD91.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Neurotrophin-3 (NTF3) DTT NTF3 5.49E-01 -0.01 -0.05
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5033).
2 NT-3. Takeda/Regeneron/Amgen. IDrugs. 2001 Jul;4(7):820-4.