Details of the Drug

General Information of Drug (ID: DMPH1RK)

Drug Name
Alferminogene tadenovec
Synonyms Generx (TN)
Indication
Disease Entry ICD 11 Status REF
Angina pectoris BA40 Phase 3 [1]
Heart disease BA41-BA42 Phase 3 [2]
Cross-matching ID
DrugBank ID
DB05306
TTD ID
D0G8UL
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fibroblast growth factor-4 (FGF4) TTCEKVZ FGF4_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Angina pectoris
ICD Disease Classification BA40
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Fibroblast growth factor-4 (FGF4) DTT FGF4 1.74E-01 0.04 0.45
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Alferminogene tadenovec, an angiogenic FGF4 gene therapy for coronary artery disease. IDrugs. 2008 Apr;11(4):283-93.