Details of the Drug

General Information of Drug (ID: DMSAOWQ)

Drug Name
Lactulose
Synonyms Cephulac;Cholac;Heptalac;Enulose;Enulose
Indication
Disease Entry ICD 11 Status REF
Constipation DD91.1 Approved [1]
Hepatic encephalopathy DB99.5 Approved [2]
Ornithine transcarbamylase deficiency 5C50.AY Approved [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C12H22O11
Canonical SMILES
C(C1C(C(C(C(O1)OC2C(OC(C2O)(CO)O)CO)O)O)O)O
InChI
1S/C12H22O11/c13-1-4-6(16)7(17)8(18)11(21-4)22-9-5(2-14)23-12(20,3-15)10(9)19/h4-11,13-20H,1-3H2/t4-,5-,6+,7+,8-,9-,10+,11+,12-/m1/s1
InChIKey
JCQLYHFGKNRPGE-FCVZTGTOSA-N
Cross-matching ID
PubChem CID
11333
ChEBI ID
CHEBI:6359
CAS Number
4618-18-2
TTD ID
D0T5BC
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Glycosyl hydrolase (glyH) DEPB9C2 A0A379KQ43_PSEPU Substrate [3]
Beta-glucosidase (bglA) DE235K6 Q3Y0M8_ENTFD Substrate [3]
Beta-galactosidase (bgaB) DEIEY19 BGAL_CROS8 Substrate [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Lactulose FDA Label
3 In vitro fermentation of lactulose by human gut bacteria. J Agric Food Chem. 2014 Nov 12;62(45):10970-7.