General Information of Drug Inactive Ingredient (DIG) (ID: E00203)

DIG Name
Cyclomethicone
Synonyms
DECAMETHYLCYCLOPENTASILOXANE; 541-02-6; Cyclopentasiloxane, decamethyl-; Cyclomethicone 5; CYCLOMETHICONE; Dimethylsiloxane pentamer; 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane; Dekamethylcyklopentasiloxan; UNII-0THT5PCI0R; Ddecamethylcyclopentasiloxane; 0THT5PCI0R; Decamethylcyclopentasiloxane, 97%; MFCD00046966; Dow corning 345 fluid; Dow corning 345; NUC silicone VS 7158; Silicon SF 1202; Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-; Cyclic dimethylsiloxane pentamer; Union carbide 7158 silicone fluid; KF 995; VS 7158; D5-sil; CCRIS 1328; HSDB 5683; Dekamethylcyklopentasiloxan [Czech]; EINECS 208-764-9; decamethyl cyclopentasiloxane; SF 1202; BRN 1800166; Ciclopentasiloxane; Cyclomethicone D5; D5 Cyclomethicone; dimethylcyclopentasiloxane; Decamethylcylopentasiloxane; DSSTox_CID_7184; ACMC-209ld1; EC 208-764-9; DSSTox_RID_78338; DSSTox_GSID_27184; SCHEMBL28497; 4-04-00-04128 (Beilstein Handbook Reference); CHEMBL1885178; DTXSID1027184; BCP15826; Tox21_303170; ANW-31955; CD3770; AKOS008901199; ZINC169743678; DB11244; MCULE-6274880347; 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane; NCGC00163981-01; NCGC00257224-01; AK608817; AS-59731; CAS-541-02-6; D1890; D3770; Decamethylcyclopentasiloxane (cyclic monomer); FT-0665531; S05475; Decamethylcyclopentasiloxane, analytical standard; Q414350; decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane; UNII-NMQ347994Z component XMSXQFUHVRWGNA-UHFFFAOYSA-N; Cyclomethicone 5, United States Pharmacopeia (USP) Reference Standard; 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane #; D5 Cyclomethicone, Pharmaceutical Secondary Standard; Certified Reference Material
DIG Function
Emollient; Humectant; Viscosity-controlling agent
Formula
C10H30O5Si5
Canonical SMILES
C[Si]1(O[Si](O[Si](O[Si](O[Si](O1)(C)C)(C)C)(C)C)(C)C)C
InChI
1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3
InChIKey
XMSXQFUHVRWGNA-UHFFFAOYSA-N
Physicochemical Properties Molecular Weight 370.77 Topological Polar Surface Area 46.2
XlogP N.A. Complexity 258
Heavy Atom Count 20 Rotatable Bond Count 0
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 5

Full List of Drug(s) Co-administrated with This DIG

4 Approved Drug(s) Co-administrated with This DIG
Drug Name Drug ID Indication Formulation Name Formulation ID
Betamethasone DMAHJEF Acute adrenal insufficiency [] Betamethasone 0.05% ointment F23642
Cinoxacin DM4EWNS Urinary tract infection [GC08] Cinoxacin 250mg capsule F23115
Efinaconazole DMFA9MV Fungal infection [1F29-1F2F] Efinaconazole 10% solution F23148
Trifarotene DMOL793 Acne vulgaris [ED80] Trifarotene 0.005% cream F23316
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