Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT06AWU)

• DTT Name: Phosphodiesterase 3A (PDE3A) DTT Info
• Gene Name: PDE3A

Molecule-Related Drug & Molecule List

5 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aminophylline	DML2NIB	Bronchial asthma	CA23	Approved	[1]
Anagrelide	DMSQ8MD	Thrombocythemia	3B63	Approved	[2]
Cilostazol	DMZMSCT	Intermittent claudication	BD40.00	Approved	[3]
Enoximone	DMQVZJD	Congestive heart failure	BD10	Approved	[4]
VESNARINONE	DMBKX3C	Cardiac failure	BD10-BD13	Approved	[5]

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BEMORADAN	DMUL6GY	Heart failure	BD10-BD13	Phase 2	[6]

5 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CI-930	DMADPQX	N. A.	N. A.	Discontinued in Phase 2	[7]
EMD-53998	DMVS8IE	Cardiovascular disease	BA00-BE2Z	Discontinued in Phase 1	[6]
BMY-20844	DMDPJ8M	N. A.	N. A.	Terminated	[8]
IMAZODAN	DMWTFO3	N. A.	N. A.	Terminated	[9]
LAS-31180	DMW2K1L	Heart failure	BD10-BD13	Terminated	[10]

26 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
1,3,9,9a-Tetrahydro-imidazo[4,5-b]quinolin-2-one	DM7U31Q	Discovery agent	N.A.	Investigative	[11]
1,3-Dihydro-imidazo[4,5-b]quinolin-2-one	DMB9XR5	Discovery agent	N.A.	Investigative	[11]
1,3-Dihydro-naphtho[2,3-d]imidazol-2-one	DM8CYOP	Discovery agent	N.A.	Investigative	[11]
1,5-Dihydro-imidazo[2,1-b]quinazolin-2-one	DMYA25G	Discovery agent	N.A.	Investigative	[12]
2-Morpholin-4-yl-8-phenylethynyl-chromen-4-one	DMNKHOI	Discovery agent	N.A.	Investigative	[13]
2-morpholino-7-(2-phenylethynyl)-4H-chromen-4-one	DM4XKYN	Discovery agent	N.A.	Investigative	[13]
2-morpholino-7-phenyl-4H-chromen-4-one	DMK7WON	Discovery agent	N.A.	Investigative	[13]
5-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one	DM0E1Y9	Discovery agent	N.A.	Investigative	[11]
6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one	DMXZWOA	Discovery agent	N.A.	Investigative	[9]
6-Imidazol-1-yl-3,4-dihydro-1H-quinolin-2-one	DMRMSU5	Discovery agent	N.A.	Investigative	[9]
6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one	DMG5ABT	Discovery agent	N.A.	Investigative	[9]
7-Chloro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one	DMWUS5Q	Discovery agent	N.A.	Investigative	[11]
7-Ethoxy-1,3-dihydro-imidazo[4,5-b]quinolin-2-one	DMI16MD	Discovery agent	N.A.	Investigative	[11]
7-Fluoro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one	DMNRCDI	Discovery agent	N.A.	Investigative	[11]
7-Iodo-1,5-dihydro-imidazo[2,1-b]quinazolin-2-one	DM6K5NF	Discovery agent	N.A.	Investigative	[12]
7-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one	DM5EQJU	Discovery agent	N.A.	Investigative	[11]
8-Chloro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one	DM5IGOL	Discovery agent	N.A.	Investigative	[11]
8-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one	DM92XPO	Discovery agent	N.A.	Investigative	[11]
8-methyl-2-morpholino-7-phenoxy-4H-chromen-4-one	DMWZ27A	Discovery agent	N.A.	Investigative	[13]
8-methyl-2-morpholino-7-phenyl-4H-chromen-4-one	DMUI1YZ	Discovery agent	N.A.	Investigative	[13]
BENZOYLENUREA	DMY5O1U	Discovery agent	N.A.	Investigative	[14]
isobutylmethylxanthine	DM46F5X	Discovery agent	N.A.	Investigative	[3]
KURAIDIN	DMLDUJ1	Discovery agent	N.A.	Investigative	[15]
KURARINOL	DMRV5YE	Discovery agent	N.A.	Investigative	[15]
SOPHOFLAVESCENOL	DM8Y1S7	Discovery agent	N.A.	Investigative	[15]
TETRAHYDROBENXIMIDAZOLE	DMNURE0	Discovery agent	N.A.	Investigative	[7]

References

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