General Information of DTT (ID: TTWM4TY)

DTT Name Adrenergic receptor alpha-2B (ADRA2B) DTT Info
Gene Name ADRA2B

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Discontinued Drug(s)
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
1 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
MOXONIDINE DMGFB0E Alcohol dependence 6C40.2 Approved [1]
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2 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
AGN-199981 DMP5Y1A Neuropathic pain 8E43.0 Phase 2 [2]
MEDETOMIDINE DMX9Y7V Pain MG30-MG3Z Phase 2 [3]
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6 Discontinued Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
INDORAMIN DMNSJFD Hypertension BA00-BA04 Withdrawn from market [4]
MAZAPERTINE DMRHYAU N. A. N. A. Discontinued in Phase 2 [5]
A-80426 DMBC3DG N. A. N. A. Terminated [6]
SK&F-104078 DMRADBU N. A. N. A. Terminated [4]
SNAP-5089 DMROJEN Heart arrhythmia BC65 Terminated [7]
WB-4101 DMQU8B1 N. A. N. A. Terminated [8]
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⏷ Show the Full List of 6 Discontinued Drug(s)
57 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
(+/-)-nantenine DM0L3GE Discovery agent N.A. Investigative [9]
(1,2,3,4-Tetrahydro-isoquinolin-3-yl)-methanol DMF6WHC Discovery agent N.A. Investigative [10]
(2-Methyl-indol-1-yl)-propyl-pyridin-4-yl-amine DME6MYZ Discovery agent N.A. Investigative [11]
(3-Ethyl-indol-1-yl)-propyl-pyridin-4-yl-amine DM5WJBH Discovery agent N.A. Investigative [11]
(3-Methyl-indol-1-yl)-propyl-pyridin-4-yl-amine DMHED9G Discovery agent N.A. Investigative [11]
(R)-3-Methyl-1,2,3,4-tetrahydro-isoquinoline DM98L2X Discovery agent N.A. Investigative [12]
(S)-3-Methyl-1,2,3,4-tetrahydro-isoquinoline DMS4JAG Discovery agent N.A. Investigative [12]
1',2',3',6'-Tetrahydro-[2,4']bipyridinyl DMFDK4N Discovery agent N.A. Investigative [13]
1,2,3,4,4a,5,10,10a-Octahydro-benzo[g]quinoline DMDYX7P Discovery agent N.A. Investigative [14]
1,2,3,4,5,6-Hexahydro-benzo[c]azocine DMTKYFE Discovery agent N.A. Investigative [12]
1,2,3,4-Tetrahydro-benzo[h]isoquinolin-8-ol DMHKANE Discovery agent N.A. Investigative [15]
1,2,3,4-Tetrahydro-isoquinolin-7-ol DM5VLIE Discovery agent N.A. Investigative [15]
1,2,3,4-Tetrahydro-pyrazino[1,2-a]indole DM3JGVF Discovery agent N.A. Investigative [16]
1,2,3,4-tetrahydroisoquinoline DMZGCEQ Discovery agent N.A. Investigative [17]
1-(3-Fluoro-pyridin-2-yl)-4-methyl-piperazine DMWFU3T Discovery agent N.A. Investigative [13]
1-(pyridin-2-yl)piperazine DMKE7FG Discovery agent N.A. Investigative [13]
2,3,4,5-Tetrahydro-1H-benzo[c]azepine DM1RE9Q Discovery agent N.A. Investigative [12]
2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine DM4EZOB Discovery agent N.A. Investigative [12]
2,3,4,5-Tetrahydro-benzo[f][1,4]oxazepine DMOFG4M Discovery agent N.A. Investigative [12]
2,3-Dihydro-1H-isoindole DMWI9XS Discovery agent N.A. Investigative [12]
2-BFi DMFAW4R Discovery agent N.A. Investigative [18]
3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline DMDPUC7 Discovery agent N.A. Investigative [19]
3-Methoxymethyl-1,2,3,4-tetrahydro-isoquinoline DMH1RX6 Discovery agent N.A. Investigative [10]
3-Methyl-1,2,3,4-tetrahydro-isoquinoline DMIWQ7G Discovery agent N.A. Investigative [12]
4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole DMFYBLH Discovery agent N.A. Investigative [3]
4-(4-Methyl-indan-1-yl)-1H-imidazole DMYZHXR Discovery agent N.A. Investigative [20]
4-Benzo[b]thiophen-4-yl-1H-imidazole DM02Q8N Discovery agent N.A. Investigative [21]
5-Aminomethyl-naphthalen-2-ol DMTP9DB Discovery agent N.A. Investigative [15]
6,7,8,9-Tetrahydro-5-thia-8-aza-benzocycloheptene DMNOI7B Discovery agent N.A. Investigative [12]
7-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline DMQ1BE8 Discovery agent N.A. Investigative [22]
8-Methoxy-1,2,3,4-tetrahydro-benzo[h]isoquinoline DMY50UR Discovery agent N.A. Investigative [15]
Butyl-indol-1-yl-pyridin-4-yl-amine DM1CX9Y Discovery agent N.A. Investigative [11]
C-(6-Methoxy-naphthalen-1-yl)-methylamine DMJ6SYI Discovery agent N.A. Investigative [15]
C-Naphthalen-1-yl-methylamine DMFW1JC Discovery agent N.A. Investigative [15]
Ethyl-indol-1-yl-pyridin-4-yl-amine DM3CWFR Discovery agent N.A. Investigative [11]
GNF-PF-2857 DML5QFZ Discovery agent N.A. Investigative [23]
GNF-PF-3878 DM7BXHQ Discovery agent N.A. Investigative [23]
imiloxan DMS4D96 Discovery agent N.A. Investigative [24]
Indol-1-yl-methyl-pyridin-4-yl-amine DMJB876 Discovery agent N.A. Investigative [11]
Indol-1-yl-prop-2-ynyl-pyridin-4-yl-amine DMR9GNW Discovery agent N.A. Investigative [11]
Indol-1-yl-pyridin-4-yl-amine DM1F53L Discovery agent N.A. Investigative [11]
JP1302 DMMVBK6 Discovery agent N.A. Investigative [23]
METHYLNORADRENALINE DMOWMPL Discovery agent N.A. Investigative [8]
MEZILAMINE DMVYWJS Discovery agent N.A. Investigative [25]
PIPEROXAN DMIHO0P Discovery agent N.A. Investigative [8]
R-226161 DM4BP7S Discovery agent N.A. Investigative [26]
S-34324 DMZLQ5W Discovery agent N.A. Investigative [6]
SK&F-64139 DM60Y3Q Discovery agent N.A. Investigative [17]
SNAP-5150 DM2OLGQ Discovery agent N.A. Investigative [7]
spiroxatrine DMPHRXQ Discovery agent N.A. Investigative [27]
TRACIZOLINE DM18CV3 Discovery agent N.A. Investigative [22]
Tramazoline DM3ML0N Discovery agent N.A. Investigative [8]
TRYPTOLINE DMV19K7 Discovery agent N.A. Investigative [22]
xylazine DMSXJUW Discovery agent N.A. Investigative [28]
[3H]MK-912 DMO89N0 Discovery agent N.A. Investigative [27]
[3H]rauwolscine DMBQZ2H Discovery agent N.A. Investigative [29]
[3H]RX821002 DM6IRN4 Discovery agent N.A. Investigative [30]
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⏷ Show the Full List of 57 Investigative Drug(s)
Molecule Interaction Atlas

References

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23 Structure-activity relationship of quinoline derivatives as potent and selective alpha(2C)-adrenoceptor antagonists. J Med Chem. 2006 Oct 19;49(21):6351-63.
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