Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTYO0A3)

• DTT Name: Substance-K receptor (TACR2) DTT Info
• Gene Name: TACR2

Molecule-Related Drug & Molecule List

4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ibodutant	DMT67EH	Irritable bowel syndrome	DD91.0	Phase 3	[1]
PMX-53	DMZUAJ4	Atopic dermatitis	EA80	Phase 2	[2]
Rambazole	DMP2DNS	Psoriasis vulgaris	EA90	Phase 2	[3]
Nepadutant	DMPMF6L	Infantile colics	DD93.1	Phase 1/2	[4]

14 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Saredutant	DMSRJY3	Anxiety disorder	6B00-6B0Z	Discontinued in Phase 3	[5]
CS-003	DM1AEVT	Chronic obstructive pulmonary disease	CA22	Discontinued in Phase 2	[6]
DNK-333	DM4ZO01	Irritable bowel syndrome	DD91.0	Discontinued in Phase 2	[7]
FK-224	DM1JUS0	Asthma	CA23	Discontinued in Phase 2	[8]
AVE-5883	DM3P84V	Asthma	CA23	Discontinued in Phase 1/2	[9]
SR 144190	DMK4XT8	Acute or chronic pain	MG30-MG31	Discontinued in Phase 1	[10]
UK-224671	DMDTRJB	Urinary incontinence	MF50.2	Discontinued in Phase 1	[11]
AZD-5106	DMABY43	Urinary incontinence	MF50.2	Terminated	[13]
GR-159897	DMLQ71Y	Anxiety disorder	6B00-6B0Z	Terminated	[14]
L-732138	DMVXKMF	N. A.	N. A.	Terminated	[15]
MEN-10207	DM185DR	Pain	MG30-MG3Z	Terminated	[16]
MEN-10627	DM35ABD	Asthma	CA23	Terminated	[17]
UK-290795	DMQFSAB	Urinary incontinence	MF50.2	Terminated	[18]
ZD-7944	DMCT1IX	Asthma	CA23	Terminated	[19]

1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SLV-332	DMY9DA3	Irritable bowel syndrome	DD91.0	Preclinical	[12]

15 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one	DMM9X0G	Discovery agent	N.A.	Investigative	[20]
A-987306	DMU34BK	Discovery agent	N.A.	Investigative	[21]
GR100679	DMP1DO4	Discovery agent	N.A.	Investigative	[22]
GR94800	DMBYK0X	Discovery agent	N.A.	Investigative	[23]
Hoo-Phe-Orn-Pro-hle-Pff-Phe-NH2	DMHW2DU	Discovery agent	N.A.	Investigative	[2]
neurokinin A	DM9UXRP	Discovery agent	N.A.	Investigative	[24]
R396	DM1OPZ9	Discovery agent	N.A.	Investigative	[25]
SCH 206272	DMD1M24	Discovery agent	N.A.	Investigative	[26]
WAY-207024	DMJ14NE	Discovery agent	N.A.	Investigative	[27]
YM44778	DMDOR2L	Discovery agent	N.A.	Investigative	[28]
YM44781	DM73AEL	Discovery agent	N.A.	Investigative	[28]
YM49598	DMTYSUN	Discovery agent	N.A.	Investigative	[28]
ZD-6021	DM8MXS6	Discovery agent	N.A.	Investigative	[29]
ZM 253270	DMA3M9H	Discovery agent	N.A.	Investigative	[30]
ZM-274773	DMD0NFL	Discovery agent	N.A.	Investigative	[31]

References

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