Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZMS1L)

DTT Name	Fungal Papulacandin B resistance protein 1 (Fung FKS1) DTT Info
Gene Name	Fung FKS1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cilofungin	DMBNWM1	Candidiasis	1F23	Terminated	[1]
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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ACULEACIN A	DMR2MUG	Discovery agent	N.A.	Investigative	[2]
L-692289	DMAB1RW	Discovery agent	N.A.	Investigative	[3]
Pyridobenzimidazole	DM3PAS4	Fungal infection	1F29-1F2F	Investigative	[4]
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Molecule Interaction Atlas

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References

1	Cryptococcus neoformans resistance to echinocandins: (1,3)beta-glucan synthase activity is sensitive to echinocandins. Antimicrob Agents Chemother. 2005 Jul;49(7):2851-6.
2	Synthesis, anti-fungal and 1,3--D-glucan synthase inhibitory activities of caffeic and quinic acid derivatives. Bioorg Med Chem. 2010 Oct 1;18(19):7009-14.
3	Antifungal lipopeptides: Structure-activity relationships of 3-hydroxyglutamine-modified pneumocandin B0 derivatives, Bioorg. Med. Chem. Lett. 5(20):2357-2362 (1995).
4	Novel antifungal agents, targets or therapeutic strategies for the treatment of invasive fungal diseases: a review of the literature (2005-2009). Rev Iberoam Micol. 2009 Mar 31;26(1):15-22.