Details of Disease

General Information of Disease (ID: DISH2UDP)

• Disease Name: Enterovirus infection
• Synonyms: disease caused by enterovirus; enterovirus infection; Enterovirus infection; infection, Enterovirus; infections, Enterovirus; enteroviral infection; disease due to enterovirus; Enterovirus infectious disease; Enterovirus caused disease or disorder; Enterovirus disease or disorder; enterovirus infectious disease
• Disease Class: 1D91: Enterovirus infection
• Definition: An disease caused by infection with Enterovirus.
• Disease Hierarchy:
  DISEM33Q: Infectious disease
  DISC80MD: Picornaviridae infectious disease
  DISH2UDP: Enterovirus infection
• ICD Code:
  ICD-11: ICD-11: 1D91
  ICD-10: ICD-10: B34.1
  ICD-9: ICD-9: 001-139
  Expand ICD-11: '1D91
  Expand ICD-10: 'B34.1
  Expand ICD-9: 001,002,003,004,005,006,007,008,009,010,011,012,013,014,015,016,017,018,019,020,021,022,023,024,025,026,027,028,029,030,031,032,033,034,035,036,037,038,039,040,041,042,043,044,045,046,047,048,049,050,051,052,053,054,055,056,057,058,059,060,061,062,063,064,065,066,067,068,069,070,071,072,073,074,075,076,077,078,079,080,081,082,083,084,085,086,087,088,089,090,091,092,093,094,095,096,097,098,099,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139
• Disease Identifiers:
  MONDO ID: MONDO_0005747
  MESH ID: D004769
  UMLS CUI: C0014378
  MedGen ID: 8647
  SNOMED CT ID: 53648006

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 4 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
KMB-17	DMYNDSL	Phase 3	NA	[1]
Human enterovirus 71 vaccine	DMWJ71W	Phase 2	NA	[2]
EV71 vaccine	DM1AWKN	Phase 1	NA	[3]
TAK-021	DM4FRE7	Phase 1	NA	[4]

This Disease is Treated as An Indication in 1 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
V-073	DMYCKGF	Discontinued in Phase 2	NA	[5]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 19 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ADRB1	TTR6W5O	Limited	Genetic Variation	[6]
APOBEC3G	TTP96KH	Limited	Biomarker	[7]
ARF1	TT70KXY	Limited	Biomarker	[8]
CA5A	TT75WPO	Limited	Biomarker	[9]
CPE	TTXPWO6	Limited	Biomarker	[10]
GBA	TT1B5PU	Limited	Altered Expression	[11]
NR4A3	TTJQB49	Limited	Biomarker	[12]
PI4KA	TTCUS9F	Limited	Biomarker	[13]
PI4KB	TTNPL3B	Limited	Altered Expression	[14]
PROKR1	TTB9CIL	Limited	Biomarker	[15]
SH3GL1	TTTYNAM	Limited	Biomarker	[16]
SSTR3	TTJX3UE	Limited	Genetic Variation	[17]
TDP2	TTYF26D	Limited	Biomarker	[18]
TNFRSF13B	TTL9OD4	Limited	Biomarker	[19]
CLEC9A	TTGUSRB	moderate	Biomarker	[20]
GAD2	TT7UY6K	Strong	Biomarker	[21]
LAMC2	TTNS7H3	Strong	Biomarker	[22]
NTSR1	TTTUMEP	Strong	Biomarker	[23]
SELPLG	TTS5K8U	Strong	Genetic Variation	[24]

This Disease Is Related to 1 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
SLC22A4	DT2EG60	Limited	Biomarker	[25]

This Disease Is Related to 2 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
WARS1	DEPVE0M	Limited	Biomarker	[26]
WARS2	DEPTKBQ	Limited	Biomarker	[26]

This Disease Is Related to 54 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
AIM2	OT86QUI8	Limited	Biomarker	[27]
ARMH3	OT51CU4J	Limited	Altered Expression	[14]
ARRDC4	OTINJ0FX	Limited	Biomarker	[28]
ATG4B	OTQ4RNRM	Limited	Altered Expression	[29]
BLNK	OTSSPF6F	Limited	Biomarker	[30]
C1QTNF6	OT57EPQC	Limited	Genetic Variation	[17]
CD48	OT83ZNPP	Limited	Biomarker	[31]
CFDP1	OTXY7J96	Limited	Biomarker	[32]
CHN1	OTM196M3	Limited	Biomarker	[12]
CPT2	OTIN6G20	Limited	Genetic Variation	[33]
CSTF2	OTR6G4II	Limited	Biomarker	[34]
EDEM1	OTWHN69S	Limited	Altered Expression	[35]
EIF4G1	OT2CF1E6	Limited	Biomarker	[36]
EIF4G2	OTEO98CR	Limited	Biomarker	[32]
FASTK	OTTHFZMP	Limited	Biomarker	[37]
GSDMB	OTWA7P10	Limited	Genetic Variation	[17]
HNRNPC	OT47AK4C	Limited	Altered Expression	[38]
HNRNPD	OT5UO1FA	Limited	Biomarker	[39]
HNRNPDL	OTB3BFCV	Limited	Altered Expression	[38]
ICAM5	OTDGGAFH	Limited	Altered Expression	[40]
KLHL12	OT671F2U	Limited	Altered Expression	[41]
KPNA1	OTEMVAJ6	Limited	Altered Expression	[42]
KREMEN1	OTGJFSAC	Limited	Biomarker	[43]
MAVS	OTTQ0J64	Limited	Biomarker	[44]
NBEAL1	OTLJ11N3	Limited	Genetic Variation	[45]
NBR1	OTVRL7J9	Limited	Biomarker	[46]
OAS2	OT64CCTM	Limited	Genetic Variation	[47]
OAS3	OT6E5FYS	Limited	Genetic Variation	[48]
PJA1	OTFKTMEI	Limited	Biomarker	[49]
PLAAT3	OTVXXJ5K	Limited	Biomarker	[50]
PSMD2	OT6HZHN7	Limited	Biomarker	[32]
PTPRN	OTAP7NOL	Limited	Altered Expression	[51]
RAB11A	OTC4FW0J	Limited	Biomarker	[52]
RALGDS	OTG36NI7	Limited	Biomarker	[53]
RREB1	OT62460U	Limited	Biomarker	[54]
RSAD2	OTCA9WCM	Limited	Biomarker	[27]
SAMHD1	OTBCIBC7	Limited	Biomarker	[55]
SCARB2	OTN929M8	Limited	Altered Expression	[56]
STAT2	OTO9G2RZ	Limited	Altered Expression	[57]
STAU1	OTTR5311	Limited	Biomarker	[58]
TRIP11	OT4FJEAR	Limited	Genetic Variation	[59]
SETD3	OTO5RAU2	moderate	Biomarker	[60]
ACBD3	OTMYNY7A	Strong	Biomarker	[61]
CA10	OTC3N1F6	Strong	Genetic Variation	[62]
CCDC88A	OT3SSYYC	Strong	Biomarker	[63]
COG1	OT3JSAF7	Strong	Biomarker	[64]
COG5	OTZEG7K0	Strong	Biomarker	[64]
GBF1	OTY1KEHY	Strong	Biomarker	[65]
MGAT5	OTU4DD4G	Strong	Biomarker	[64]
OSBP	OT7R0OQQ	Strong	Biomarker	[66]
SARS1	OTFKXQ1O	Strong	Biomarker	[67]
SARS2	OTU4T99W	Strong	Biomarker	[67]
ST3GAL1	OTFCO8QX	Strong	Biomarker	[64]
ST3GAL4	OTNENJZQ	Strong	Biomarker	[64]

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