Details of the Drug Combinations

General Information of This Drug (ID: DMQEJVU)

Drug Name
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole   DMQEJVU
Synonyms
1-((2-Chlorophenyl)diphenylmethyl)-1H-pyrazole; TRAM-34; 289905-88-0; Tram 34; 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole; AC1LCVHZ; CHEMBL498270; CHEBI:34990; 1-[(2-chlorophenyl)-diphenylmethyl]pyrazole; 1-(2-Chlorophenyl)diphenyl)methyl]-1H-pyrazole; SureCN41130; TRAM34; SCHEMBL41130; GTPL2336; KS-00000OJW; CTK0J1643; DTXSID70349650; MolPort-003-850-592; EX-A2316; BCP01324; ZINC3975392; BDBM50279107; ANW-72309; s1160; MFCD09842562; AKOS005146304; CS-1921; ACN-048484; MP-2041; API0000868; DS-2617; NCGC00165909-03; NCGC00165909-02
Indication
Disease Entry ICD 11 Status REF
Conjunctival fibrosis 9A61.3 Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

52 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Meclofenamic acid DCZ05JX Meclofenamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Ribavirin-TP DCGJMG6 Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Triiodothyronine DCH45RX Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Gefitinib DC9MYUD Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Epinephrine DCW9862 Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Fomepizole DCHQ326 Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Testosterone DCOKJT3 Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Triapine DCE3NJ1 Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Everolimus DCO1WDG Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + IT-141 DCKJSSQ IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Terameprocol DCBQGL5 Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Itraconazole DCNQ5DC Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Chlorzoxazone DC3BR6B Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Metformin DC9WBG5 Metformin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Marizomib DC3YWC5 Marizomib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Clopidogrel DCC54HH Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + BIO-300 DCGG4XJ BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Isoproterenol DCBY3J2 Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Tiagabine DCQN6BD Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Diazoxide DCBJ5P7 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Allopurinol DC1YMUJ Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Imatinib DCTQ2Y7 Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Atenolol DCUHS7M Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Bortezomib DCCE1PI Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Brincidofovir DCF2LU3 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Hyodeoxycholic acid DC5VCWP Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Mycophenolic acid DCC8G01 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Auranofin DCOA7RJ Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Rufinamide DCIOIDF Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Vorinostat DCX5P8Y Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Cerivastatin DCCSQXH Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Aciclovir DC9KP77 Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Acetohydroxamic Acid DCEMJ9A Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Cytarabine DCMTE7I Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acitretin + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DC20B88 Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Artemisinin + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCK4225 Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
AS-1949490 + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCRNP9O AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cisatracurium + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCNJ2MD Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dichlorphenamide + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCC9WV1 Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Docetaxel + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCT66CO Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Imipramine + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCTXQDA Imipramine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
JZL195 + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DC1N8AU JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCJLLMB Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metaxalone + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DC4G9WA Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Naltrexone + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCIN0YA Naltrexone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DC4USQB Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PF-02545920 + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCEXSKD PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PMID28460551-Compound-2 + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DC4IYNW PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sertraline + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DC4LPT0 Sertraline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Teriflunomide + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCHOZEQ Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trimethobenzamide + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCR2OZR Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vinblastine + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCQ6NWU Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 52 DrugCom(s)

References

1 Blockade of KCa3.1: A novel target to treat TGF-1 induced conjunctival fibrosis.Exp Eye Res. 2018 Feb;167:140-144.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.