Details of the Drug Combinations

General Information of This Drug (ID: DMQPH29)

Drug Name

Curcumin DMQPH29

Synonyms

curcumin; 458-37-7; Diferuloylmethane; Natural yellow 3; Turmeric yellow; Turmeric; Curcuma; Kacha haldi; Gelbwurz; Indian saffron; Curcumin I; Souchet; Halud; Halad; Haidr; Haldar; Merita earth; Yellow Ginger; Terra Merita; Yellow Root; Safran d'Inde; Yo-Kin; Golden seal; Curcuma oil; Orange Root; Oils, curcuma; CI Natural Yellow 3; Curcumine; Hydrastis; Indian turmeric; Yellow puccoon; Turmeric extract; Diferaloylmethane; Kurkumin [Czech]; (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione; Tumeric yellow; Turmeric oil

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 3	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Curcumin + OZ277	DC558CB	OZ277	DD2 (Cell Line: DD2)	[2]
Curcumin + Idarubicin	DCCB4TV	Idarubicin	Glioblastoma? (Cell Line: T98G)	[2]
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4 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Armodafinil + Curcumin	DCLOZU5	Armodafinil	Non Small Cell Lung Cancer	[3]
Bupropion + Curcumin	DC4HV40	Bupropion	Non Small Cell Lung Cancer	[3]
URSOLIC ACID + Curcumin	DCMJ878	URSOLIC ACID	Prostate Cancer	[4]
Curcumin + Artesunate	DCZ8E1J	Artesunate	Crohn's Disease	[5]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7000).
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3	ClinicalTrials.gov (NCT01048983) Reducing Symptom Burden - Non Small Cell Lung Cancer (NSCLC)
4	ClinicalTrials.gov (NCT04403568) Testing the Synergism of Phytonutrients, Curcumin and Ursolic Acid, to Target Molecular Pathways in the Prostate
5	ClinicalTrials.gov (NCT04713631) Safety and Efficacy of Artesunate & Curcumin in Crohn's Disease