General Information of This Drug (ID: DMT5HA4)

Drug Name
Ketamine   DMT5HA4
Synonyms
Calypsol; Cetamina; Green; Ketaject; Ketalar; Ketaminum; Ketanest; Ketoject; Ketolar; Tekam; KETAMINE HCL; Ketalar base; Ketamine Base; Special K; Special K [street name]; CLSTA 20; T385; Cetamina [INN-Spanish]; Dl-Ketamine; Ketalar (TN); Ketamine (INN); Ketamine [INN:BAN]; Ketaminum [INN-Latin]; Ketanest (TN); Ketaset (TN); Tekam (TN); Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-(9CI); Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)-(9CI); Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+/-)-(8CI); (+/-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone; (+/-)-2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone; 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone; 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one; 2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone; 2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone; 2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
Indication
Disease Entry ICD 11 Status REF
Anaesthesia 9A78.6 Approved [1]
Anxiety N.A. Approved [2]
Bipolar disorder 6A60 Approved [2]
Depression 6A70-6A7Z Approved [2]
Traumatic brain injury NA07.Z Approved [2]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [3]
Chronic pain MG30 Investigative [2]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Analgesics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

54 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Ketamine + Dexamethasone DCMI6K1 Dexamethasone Hemorrhoids [4]
Ketamine + Fentanyl DCFJOV0 Fentanyl Procedural Sedation and Analgesia [5]
Ketamine + Propofol DCHENMG Propofol Trauma [6]
Ketamine + Ketamine DCSDUHM Ketamine Postoperative Pain Management [7]
Ketamine + Lamotrigine DCU67YY Lamotrigine Major Depression [8]
Ketamine + Morphine DC0BTFI Morphine Acute Pain [9]
Ketamine + Ropivacaine DC1PV7G Ropivacaine Branchial Plexus Blockade [10]
Ketamine + Clonidine DC24WFO Clonidine Depressive Disorder, Treatment-Resistant [11]
Ketamine + Midazolam DC5U3JU Midazolam Bipolar Disorder [12]
Ketamine + Esketamine DCN4IIW Esketamine Treatment Resistant Depression [13]
Ketamine + Methohexital DCQU2CF Methohexital Post-anesthesia Recovery [14]
Ketamine + Riluzole DCTF6EK Riluzole Major Depression [8]
Ketamine + PF-04958242 DCW0FIZ PF-04958242 Schizophrenia [15]
Ketamine + Propofol DCW7096 Propofol Endoscopy [16]
Ketamine + Amitriptyline DC6C229 Amitriptyline Neuropathic pain; Diabetic neuropathy; Postherpetic neuralgia [17]
Ketamine + Gabapentin DCBTL8M Gabapentin Head and Neck Cancer [18]
Ketamine + Modafinil DCJZ2G6 Modafinil Cognitive Symptom [19]
Ketamine + Lamotrigine DCQZTVE Lamotrigine Mental Disorders [20]
Ketamine + E-2007 DCY4FMV E-2007 Depressive Disorder, Major [21]
Ketamine + Gabapentin DC0QGDX Gabapentin Pain [22]
Ketamine + Ketorolac DCN8JGT Ketorolac Pain Management [23]
Ketamine + Morphine DCTFQ3X Morphine Progressive Infantile Idiopathic Scoliosis [24]
Ketamine + Naltrexone DC71OWP Naltrexone COVID-19 [3]
Ketamine + Sufentanil DC8FXUH Sufentanil Pain [25]
Ketamine + Milnacipran DC9JT8E Milnacipran Depression [26]
Ketamine + Sevoflurane DCBWKJW Sevoflurane Anesthesia [27]
Ketamine + Minocycline DCCUPIS Minocycline Depressive Disorder [28]
Ketamine + Dibucaine DCEKG8S Dibucaine Postoperative Pain [29]
Ketamine + Nitroprusside DCMQI15 Nitroprusside Depression [30]
Ketamine + Lithium Carbonate DCPJEPA Lithium Carbonate Treatment Resistant Depression [31]
Ketamine + Oxycodone DCQOZJW Oxycodone Acute Pain [32]
Ketamine + Levobupivacaine DCQWMOV Levobupivacaine Analgesia [33]
Ketamine + Naltrexone DCVFSTI Naltrexone Obsessive-Compulsive Disorder [34]
Ketamine + E-2007 DCYE9F0 E-2007 Depressive Disorder [35]
Ketamine + Lidocaine DCECJVF Lidocaine Septic Shock [36]
Ketamine + Lidocaine DCVAQBE Lidocaine Postoperative Pain [37]
Ketamine + Pregabalin DCVZAE6 Pregabalin Phantom Pain [38]
Ketamine + Alvimopan DCC7TV8 Alvimopan Acute Pain [39]
Ketamine + Dexamethasone DCG4UQF Dexamethasone Pain, Postoperative [40]
Ketamine + Clonidine DCIZ4US Clonidine Postoperative Pain [41]
Ketamine + Ondansetron DCMUQ47 Ondansetron Trigeminal Neuralgia [42]
Ketamine + Fluoxetine DCQPY5H Fluoxetine Bipolar Disorder [43]
Ketamine + Fentanyl DCSVZZV Fentanyl Ketamine [44]
Ketamine + Fentanyl DCVAZPS Fentanyl Prostatic Cancer [45]
Ketamine + Midazolam DC9944V Midazolam Emergence Agitation [46]
Ketamine + Methadone DCD1HJT Methadone Laminectomy [47]
Ketamine + Dexamethasone DCDC6N8 Dexamethasone Pain, Postoperative [48]
Ketamine + Propofol DCDT501 Propofol Retinopathy [49]
Ketamine + Rocuronium DCKCV4D Rocuronium Inguinal Hernia [50]
Ketamine + Esketamine DCMABAL Esketamine Major Depressive Disorder [51]
Ketamine + Remifentanil DCNHCDZ Remifentanil Delayed Emergence From Anesthesia [52]
Ketamine + Sevoflurane DCUGEB4 Sevoflurane Depressive Disorder [53]
Ketamine + Fentanyl DCW1QAK Fentanyl Postoperative Pain [54]
Ketamine + Remifentanil DCZOOOT Remifentanil Pediatric Rigid Bronchoscopy [55]
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⏷ Show the Full List of 54 DrugCom(s)

References

1 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 076092.
2 Ketamine FDA Label
3 ClinicalTrials.gov (NCT04365985) Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19. U.S. National Institutes of Health.
4 ClinicalTrials.gov (NCT02402543) Pre-Emptive Analgesia in Ano-Rectal Surgery
5 ClinicalTrials.gov (NCT01126957) Combined Ketamine/Propofol for Emergency Department Procedural Sedation
6 ClinicalTrials.gov (NCT04291521) Prospective Study of Induction Medications Used in the Trauma RSI
7 ClinicalTrials.gov (NCT01070108) Escalating Ketamine Doses and Pre-emption
8 ClinicalTrials.gov (NCT00419003) Research Study for Major Depressive Disorder: Investigation of Glutamate Medications
9 ClinicalTrials.gov (NCT01900847) Ketamine and Morphine Versus Morphine Alone for the Treatment of Acute Pain in the Emergency Department
10 ClinicalTrials.gov (NCT05297422) Axillary Approach to Brachial Plexus Blockade Using Ketamine, Regional Versus Intravenous Administration
11 ClinicalTrials.gov (NCT01179009) Treatment Resistant Depression (Pilot)
12 ClinicalTrials.gov (NCT00947791) Treatment Study of Bipolar Depression
13 ClinicalTrials.gov (NCT04480918) University of Iowa Interventional Psychiatry Service Patient Registry
14 ClinicalTrials.gov (NCT01567852) Use of Ketamine vs Methohexital for Electroconvulsive Therapy (ECT) on Patient Recovery and Re-orientation Time
15 ClinicalTrials.gov (NCT01749098) A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers
16 ClinicalTrials.gov (NCT00614159) Ketamine Compared to Propofol for Pediatric GI Endoscopy
17 FDA Drug Development and Drug Interactions
18 ClinicalTrials.gov (NCT05156060) Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer
19 ClinicalTrials.gov (NCT03469089) Touchscreen-based Cognitive Tests in Healthy Volunteers
20 ClinicalTrials.gov (NCT02708849) The Sustained Effects of Ketamine
21 ClinicalTrials.gov (NCT03367533) Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
22 ClinicalTrials.gov (NCT02815111) Evaluation of Ketamine and Multi-modal Analgesics
23 ClinicalTrials.gov (NCT05597878) Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy
24 ClinicalTrials.gov (NCT02571491) Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery
25 ClinicalTrials.gov (NCT05508594) Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001
26 ClinicalTrials.gov (NCT02783430) Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
27 ClinicalTrials.gov (NCT03503578) EEG Studies of Sevoflurane-Induced General Anesthesia
28 ClinicalTrials.gov (NCT01809340) The Effect of Minocycline on Relapse After Successful Intravenous Ketamine/Minocycline-induced Symptoms Response in Subjects With Depression
29 ClinicalTrials.gov (NCT02462174) Topical Ketamine Versus Caudal Ketamine for Postoperative Analgesia in Children Undergoing Inguinal Herniotomy
30 ClinicalTrials.gov (NCT03102736) Ketamine and Nitroprusside for Depression
31 ClinicalTrials.gov (NCT03290963) Effect of Lithium Versus Placebo in Adults With Treatment-Resistant Depression Who Are Receiving Ketamine
32 ClinicalTrials.gov (NCT02541396) A Study Of The Effectiveness Of Wafermine Alone And In Combination With Opioids In Subjects Undergoing Bunionectomy
33 ClinicalTrials.gov (NCT04275661) Ketamine Versus Magnesium Sulphate as Adjuvants for ESPB in Breast Cancer Surgery
34 ClinicalTrials.gov (NCT05940324) Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
35 ClinicalTrials.gov (NCT05786066) The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
36 ClinicalTrials.gov (NCT03640468) Lidocaine as an Adjuvant for Ketamine in Induction of Anesthesia in Septic Shock Patients
37 ClinicalTrials.gov (NCT01983020) Peri-Operative Lidocane, Ketamine, or Lidocane and Ketamine Combination, Infusion for Patients Undergoing Spine Surgery
38 ClinicalTrials.gov (NCT02311777) Pre-operative Pregabalin and Ketamine to Prevent Phantom Pain
39 ClinicalTrials.gov (NCT02785003) Ketamine in Colorectal Surgery
40 ClinicalTrials.gov (NCT02989597) Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients
41 ClinicalTrials.gov (NCT03124082) OFA - Opioid Free Anesthesia
42 ClinicalTrials.gov (NCT03152955) Postoperative Analgesia in Patients With Microvascular Decompression
43 ClinicalTrials.gov (NCT01833897) NMDA Antagonists in Bipolar Depression
44 ClinicalTrials.gov (NCT03666494) Ketamine Co-induction for Patients With Major Depressive Disorder
45 ClinicalTrials.gov (NCT02909049) Clinical Trial to Examine Individual Pain Tolerance in the Use of Two Anesthetic Techniques to Perform Saturation Prostate Biopsy
46 ClinicalTrials.gov (NCT02022488) Sevoflurane Induced Emergence Agitation
47 ClinicalTrials.gov (NCT02252432) The Effects of Ketamine and Methadone on Postoperative Pain for Laminectomy
48 ClinicalTrials.gov (NCT04751175) Management of Pain in Lumbar Arthrodesis
49 ClinicalTrials.gov (NCT01955135) Anesthesia for Retinopathy of Prematurity
50 ClinicalTrials.gov (NCT02646709) The Effect of Different Dose of Ketamine With Low Dose Rocuronium in Children
51 ClinicalTrials.gov (NCT05450432) Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
52 ClinicalTrials.gov (NCT02602743) Propofol-Ketamine vs Remifentanyl-Ketamine for Sedation in Pediatric Patients Undergoing Colonoscopy
53 ClinicalTrials.gov (NCT02267980) Effect of the Addition of Ketamine to Sevoflurane Anesthesia in Electroconvulsive Therapy
54 ClinicalTrials.gov (NCT03052673) Ketamine for Pain Relief in Bariatric Surgery
55 ClinicalTrials.gov (NCT01947114) Remifentanil Use in Pediatric Rigid Bronchoscopy