General Information of This Drug (ID: DMYZ57N)

Drug Name
Albendazole   DMYZ57N
Synonyms
Albendazol; Albendazolum; Albendoral; Albenza; Bendapar; Bilutac; Digezanol; Disthelm; Endoplus; Eskazole; Gascop; Lurdex; Metiazol; Proftril; Valbazen; Zental; Zentel; Albendazole Armstrong Brand; Albendazole Diba Brand; Albendazole Fustery Brand; Albendazole Hormona Brand; Albendazole Liferpal Brand; Albendazole Monohydrochloride; Albendazole Pfizer Brand; Albendazole Sanicoopa Brand; Albendazole Valdecasas Brand; Armstrong Brand of Albendazole; Diba Brand of Albendazole; Fustery Brand of Albendazole; Hormona Brand of Albendazole; Liferpal Brand of Albendazole; Mediamix V Disthelm; Noe Socopharm Brand of Albendazole; Pfizer Brand of Albendazole; Sanicoopa Brand of Albendazole; SmithKline Beecham Brand of Albendazole; Valdecasas Brand of Albendazole; SKF 62979; SKF62979; Albendazol [INN-Spanish]; Albendazole Noe-Socopharm Brand; Albendazolum [INN-Latin]; Albenza (TN); Disthelm, Mediamix V; Eskazole (TN); Monohydrochloride, Albendazole; Noe-Socopharm Brand of Albendazole; SK&F 62979; SK&F62979; SKF-62979; Smith Kline & French Brand of Albendazole; V Disthelm, Mediamix; Zentel (TN); SK&F-62979; Albendazole (JAN/USP/INN); Albendazole [USAN:INN:BAN:JAN]; Albenza, Eskazole, Zentel, Andazol, Albendazole; Methyl 5-(propylthio)-2-benzimidazolecarbamate; Methyl [5-(Propylthio)benzimidazol-2-yl]carbamate; Methyl-5-[propylthio]-2-benzimidazole carbamate; [5-(Propylthio)benzimidazol-2-yl]carbamic Acid Methyl Ester; Methyl 5-(propyl-thio)-2-benzimidazolecarbamate; Methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate; Methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate; Methyl [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate; [5-(Propythio)-1H-benzimidazol-2-yl]carbamic acid methyl ester; MethylN-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate; O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate; Carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester; Methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate; CARBAMIC ACID, (5-(PROPYLTHIO)-1H-BENZIMIDAZOL-2-YL)-, METHYL ESTER; Methyl [(2Z)-5-(propylsulfanyl)-1,3-dihydro-2H-benzimidazol-2-ylidene]carbamate; ((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle; ((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle [French]; (5-(Propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester; (5-Propylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester; 5-(Propylthio)-2-carbomethoxyaminobenzimidazole
Indication
Disease Entry ICD 11 Status REF
Echinococcus granulosus infectious disease N.A. Approved [1]
Helminth infection 1F90.0 Approved [1]
Worm infection 1F90.Z Approved [2]
Therapeutic Class
Antiprotozoal Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

63 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Albendazole + Lefaxin DCVQ6UQ Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Aliskiren DCFRSPY Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Methotrexate DCJNMKU Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Dihydroergotamine DCYJ2VK Dihydroergotamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Ramelteon DCVVC9Y Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Triapine DCDRN8G Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + IT-141 DCTEVXV IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Ursodeoxycholic acid DCQ3CRD Ursodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Doxapram DCH8Q8E Doxapram Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + K-134 DCFEV9R K-134 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Docetaxel DC7010B Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Aminosalicylic acid DC1Y8QM Aminosalicylic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Daidzin DCX3YVZ Daidzin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Zaleplon DC7ACTF Zaleplon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Diphenidol DCUYATA Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + PF-02545920 DC4SQ1R PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Tiagabine DCBYVC5 Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Diazoxide DCUGPP2 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Leflunomide DC9Z1OZ Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Theophylline DC9MJ5C Theophylline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Brincidofovir DCDMU8Q Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Estramustine DCX95CD Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Cerivastatin DC06EYD Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + ML323 DC85RDL ML323 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Albendazole + Tacrolimus DC6DZ66 Tacrolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Allopurinol + Albendazole DC1COHI Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Amiloride + Albendazole DCMP9SZ Amiloride Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Amodiaquine + Albendazole DCIQW6K Amodiaquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Arfolitixorin + Albendazole DCSG7KY Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Artemisinin + Albendazole DC2PEXL Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Benserazide + Albendazole DCL06RP Benserazide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Bortezomib + Albendazole DC30PG1 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Brincidofovir + Albendazole DC2RMEM Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cerivastatin + Albendazole DC9CS45 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Citalopram + Albendazole DC0DD1A Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clascoterone + Albendazole DCQCO22 Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clopidogrel + Albendazole DC6QART Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cytarabine + Albendazole DCBH9R4 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dactinomycin + Albendazole DCDBSB2 Dactinomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Dexmedetomidine + Albendazole DCK6IVT Dexmedetomidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diphenidol + Albendazole DCJYKGC Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Efavirenz + Albendazole DC1D2OR Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ethambutol + Albendazole DC5O24V Ethambutol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Etomidate + Albendazole DCER8RW Etomidate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Everolimus + Albendazole DCBHBXV Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Hydralazine + Albendazole DC76SZ3 Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebutamate + Albendazole DC5KFBL Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mefloquine + Albendazole DCFU6M1 Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methocarbamol + Albendazole DCHOQ9B Methocarbamol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Albendazole DC9BDWL Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pazopanib + Albendazole DCA8H4Q Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pinacidil + Albendazole DCDYRRM Pinacidil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Probenecid + Albendazole DC5Y46S Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Repaglinide + Albendazole DCONIBX Repaglinide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Sulfapyridine + Albendazole DCOGFBI Sulfapyridine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tamoxifen + Albendazole DCK67ZD Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Teriflunomide + Albendazole DCF8T62 Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tolvaptan + Albendazole DCB5QWD Tolvaptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Topotecan + Albendazole DCAZKEA Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Trihexyphenidyl + Albendazole DCO4NFE Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trimethobenzamide + Albendazole DCKO7O8 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vinblastine + Albendazole DCIZK5A Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vorinostat + Albendazole DC21Z53 Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 63 DrugCom(s)
8 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Diethylcarbamazine + Albendazole DCFM8VY Diethylcarbamazine Lymphatic Filariasis [5]
Praziquantel + Albendazole DCBB67T Praziquantel HIV Infections [6]
Ivermectin + Albendazole DCKYM7E Ivermectin Malaria [7]
Azithromycin + Albendazole DCTSVGW Azithromycin Moderate Acute Malnutrition [8]
Moxidectin + Albendazole DCDFVQA Moxidectin Lymphatic Filariasis [9]
Moxidectin + Albendazole DCYNMAD Moxidectin Onchocerciasis [10]
Albendazole + Oxantel pamoate DCTAVOU Oxantel pamoate Hookworm Infection [11]
Azithromycin + Albendazole DCI4GCM Azithromycin Helminth Infection [12]
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⏷ Show the Full List of 8 DrugCom(s)

References

1 Albendazole FDA Label
2 Opportunities and challenges in antiparasitic drug discovery. Nat Rev Drug Discov. 2005 Sep;4(9):727-40.
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.
5 ClinicalTrials.gov (NCT00511004) Effect of Albendazole Dose on Treatment of Lymphatic Filariasis
6 ClinicalTrials.gov (NCT00507221) Empiric Therapy of Helminth Co-infection to Reduce HIV-1 Disease Progression
7 ClinicalTrials.gov (NCT02509481) Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study
8 ClinicalTrials.gov (NCT03474276) Comparing Several Strategies to Manage Moderate Acute Malnutrition Among Children From 6 to 24 Months Old
9 ClinicalTrials.gov (NCT04410406) Moxidectin for LF, Cote d'Ivoire (DOLF)
10 ClinicalTrials.gov (NCT04311671) Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole
11 ClinicalTrials.gov (NCT03278431) Triple Combinations Against Hookworm Infections in Lao
12 ClinicalTrials.gov (NCT03032042) Intestinal Microbiome Post-Azythromycin/Albendazole Treatment