Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM98IXF)

Drug Name
Triamcinolone Drug Info
Synonyms
Adcortyl; Aristocort; Celeste; Cinolone; Delphicort; Fluoxiprednisolone; Fluoxyprednisolone; Fougera; Ione; Kenacort; Ledercort; Mycolog; Omcilon; Omicilon; Orion; Rodinolone; Tiamcinolonum; Triamcet; Triamcinalone; Triamcinlon; Triamcinolon; Triamcinolona; Triamcinolonum; Tricortale; Trilone; Tristoject; Volon; Aristocort Tablets; Triamcinolonum [INN]; CL 19823; Aristocort (TN); Azmacort (TN); Cinolone-T; Fougera (TN); Kenacort (TN); Kenacort-AG; Kenalog (TN); Nasacort (TN); SK-Triamcinolone; Tiamcinolonum [INN-Latin]; Triam-Tablinen; Triamcinolona [INN-Spanish]; Tricortone (TN); Triderm (TN); Triesence (TN); Trilone (TN); Tristoject (TN); Volon A (TN); Tri-Nasal (TN); Triamcinolone (JP15/USP/INN); Triamcinolone [USAN:INN:BAN:JAN]; Droxypregna-1,4-diene-3,20-dione; Pregna-1,4-diene-3,20-dio; TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7)); Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy-(8CI); Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha); (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; 11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione; 11.Beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione; 11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione; 9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione; 9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione; 9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione; 9-alpha-Fluoro-16-alpha-hydroxyprednisolone; 9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy; 9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione; 9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d; 9.Alpha.-Fluoro-16.alpha.-hydroxyprednisolone; 9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione; 9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione; 9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione; 9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone; 9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione; 9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione; 9alpha-Fluoro-16alpha-hydroxyprednisolone
Indication
Disease Entry ICD 11 Status REF
Acute adrenal insufficiency Approved [1]
Addison disease 5A74.0 Approved [1]
Allergic rhinitis CA08.0 Approved [2]
Alopecia areata ED70.2 Approved [1]
Angioedema 4A00.15 Approved [1]
Aspiration pneumonitis Approved [1]
Autoimmune haemolytic anaemia 3A20 Approved [1]
Bacterial infection 1A00-1C4Z Approved [1]
Bursitis Approved [1]
Cerebral edema 8D60.1 Approved [1]
Congenital adrenal hyperplasia 5A71.01 Approved [1]
Crohn disease DD70 Approved [1]
Cutaneous candidiasis 1F23.14 Approved [1]
Dermatitis herpetiformis EB44 Approved [1]
Diamond-Blackfan anemia Approved [1]
Disorder of orbital region Approved [1]
Epicondylitis Approved [1]
Erythema multiforme Approved [1]
Exanthem Approved [1]
Gingival disorder Approved [1]
Granuloma annulare Approved [1]
Inflammation 1A00-CA43.1 Approved [1]
Inflammatory bowel disease DD72 Approved [1]
Miliary tuberculosis Approved [1]
Multiple sclerosis 8A40 Approved [1]
Mycosis fungoides 2B01 Approved [1]
Primary cutaneous T-cell lymphoma Approved [1]
Psoriasis EA90 Approved [1]
Psoriatic arthritis FA21 Approved [1]
Rheumatic heart disease Approved [1]
Sarcoidosis 4B20.5 Approved [1]
Seasonal allergic rhinitis CA08.01 Approved [1]
Serum sickness Approved [1]
Severe asthma CA23 Approved [1]
Skin disease EA00-EM0Z Approved [1]
Subacute bursitis Approved [1]
Sympathetic ophthalmia Approved [1]
Systemic lupus erythematosus 4A40.0 Approved [1]
Acquired thrombocytopenia Investigative [1]
Asthma CA23 Investigative [1]
Beta-thalassemia major Investigative [1]
Classic Hodgkin lymphoma Investigative [1]
Follicular lymphoma 2A80 Investigative [1]
Keloid EE60 Investigative [1]
Rheumatoid arthritis FA20 Investigative [1]
Synovitis Investigative [1]
Trichinellosis Investigative [1]
Uveitis 9A96.Z Investigative [1]
Therapeutic Class
Antiinflammatory Agents
Cross-matching ID
PubChem CID
31307
ChEBI ID
CHEMBL1451
CAS Number
CAS 124-94-7
TTD Drug ID
DM98IXF
ACDINA Drug ID
D01501

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Glucocorticoid receptor (NR3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [7]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [3]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [8]
Fluticasone DMGCSVF Allergic rhinitis CA08.0 Approved [9]
Betamethasone Valerate DMMIAXO Dermatological disease DA24.Y Approved [3]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [3]
Deflazacort DMV0RNS Duchenne dystrophy 8C70 Approved [3]
Prednisone DM2HG4X Acute asthma CA23 Approved [10]
Budesonide DMJIBAW Allergic rhinitis CA08.0 Approved [11]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pro-opiomelanocortin (POMC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [13]
Prednisone DM2HG4X Acute asthma CA23 Approved [14]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [15]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [16]
Fentanyl DM8WAHT Analgesia MB40.8 Approved [17]
Cyproheptadine DM92AH3 Allergic rhinitis CA08.0 Approved [18]
Buspirone DMBS632 Anxiety disorder 6B00-6B0Z Approved [19]
Ethanol DMDRQZU Chronic pain MG30 Approved [20]
Metyrapone DMI7FVQ Cushing disease 5A70 Approved [21]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [22]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [23]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [24]
Gefitinib DM15F0X Colon adenocarcinoma Approved [25]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [27]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [28]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [29]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [31]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serotransferrin (TF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [33]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [35]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [36]
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [38]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [39]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [40]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [41]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [42]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucocorticoid receptor (NR3C1) TTYRL6O GCR_HUMAN Modulator [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Gene/Protein Processing [4]
Pro-opiomelanocortin (POMC) OTV41F7T COLI_HUMAN Protein Interaction/Cellular Processes [5]
Serotransferrin (TF) OT41PEMS TRFE_HUMAN Drug Response [6]
Vascular endothelial growth factor A, long form OTIM9MZ3 VEGFA_HUMAN Gene/Protein Processing [4]

References

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29 Dimethyl Fumarate Inhibits the Nuclear Factor B Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein. J Biol Chem. 2016 Feb 12;291(7):3639-47. doi: 10.1074/jbc.M115.679704. Epub 2015 Dec 18.
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