Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMP204G)

Drug Name
METHYLENEDIOXYAMPHETAMINE Drug Info
Synonyms
Tenamfetamine; 3,4-methylenedioxyamphetamine; Methylenedioxyamphetamine; 4764-17-4; 3,4-Methylenedioxy-amphetamine; MDA (pharmaceutical); Tenamfetamine [INN]; Tenamfetaminum [Latin]; Tenamfetamina [Spanish]; 1-(1,3-benzodioxol-5-yl)propan-2-amine; BRN 0150196; DEA No. 7400; AI3-24882; alpha-Methyl-1,3-benzodioxole-5-ethanamine; 1,3-Benzodioxole-5-ethanamine, alpha-methyl-; CHEMBL6731; ALPHA-METHYL-3,4-(METHYLENEDIOXY)PHENETHYLAMINE; NGBBVGZWCFBOGO-UHFFFAOYSA-N; 5-19-08-00417 (Beilstein Handbook Reference); Phenethylamine, alp
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
1614
ChEBI ID
CHEBI:166520
CAS Number
CAS 4764-17-4
TTD Drug ID
DMP204G
VARIDT Drug ID
DR00861

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Norepinephrine transporter (NET)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [5]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [6]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [7]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [5]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [8]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [9]
Tapentadol hydrochloride DMXLSH3 Acute pain MG31 Approved [10]
Venlafaxine DMR6QH0 Anxiety disorder 6B00-6B0Z Approved [9]
Trimipramine DM1SC8M Major depressive disorder 6A70.3 Approved [11]
Duloxetine DM9BI7M Depression 6A70-6A7Z Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Serotonin transporter (SERT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [5]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [6]
Fluoxetine DM3PD2C Bipolar depression Approved [13]
Vortioxetine DM6F1PU Major depressive disorder 6A70.3 Approved [14]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [15]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [8]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [9]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [13]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [13]
Trazodone DMK1GBJ Depression 6A70-6A7Z Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Dopamine transporter (DAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [8]
Dasotraline DMLDQFV Attention deficit hyperactivity disorder 6A05.Z Approved [16]
Methylphenidate DM7SJD6 Attention deficit hyperactivity disorder 6A05.Z Approved [17]
Modafinil DMYILBE Malignant glioma 2A00.0 Approved [13]
Phenmetrazine DMXYTN9 Obesity 5B81 Approved [18]
Ioflupane i-123 DMNARJT Parkinson disease 8A00.0 Approved [19]
DEXMETHYLPHENIDATE HYDROCHLORIDE DM8WBAH Attention deficit hyperactivity disorder 6A05.Z Approved [20]
Altropane DMO9WDS Attention deficit hyperactivity disorder 6A05.Z Approved [21]
Amitifadine DMS1X67 Obesity 5B81 Phase 3 [22]
NAV5001 DMRSI1M Dementia 6D80-6D86 Phase 3 [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [23]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [3]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [24]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [25]
Cepharanthine DM9Y5JB N. A. N. A. Approved [26]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [27]
Clozapine DMFC71L Schizophrenia 6A20 Approved [28]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [29]
Trifluoperazine DMKBYWI Anxiety Approved [30]
Olanzapine DMPFN6Y Bipolar depression Approved [28]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Prostaglandin G/H synthase 2 (PTGS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [31]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [32]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [33]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [34]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [35]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [36]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [37]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [38]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [39]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [40]
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Drug(s) Affected By Prostaglandin G/H synthase 1 (PTGS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [43]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [44]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Bupivacaine DM4PRFC Anaesthesia 9A78.6 Approved [47]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [46]
Panobinostat DM58WKG Chronic graft versus host disease Approved [48]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine transporter (DAT) TTVBI8W SC6A3_HUMAN Inhibitor [1]
Norepinephrine transporter (NET) TTAWNKZ SC6A2_HUMAN Inhibitor [1]
Serotonin transporter (SERT) TT3ROYC SC6A4_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [3]
Prostaglandin G/H synthase 1 (PTGS1) OTHCRLEC PGH1_HUMAN Drug Response [4]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Drug Response [4]

References

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