Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMP3BZH)

Drug Name

Fusion peptide EK1 Drug Info

Synonyms

EK1 peptide

Indication

Disease Entry	ICD 11	Status	REF
Middle East Respiratory Syndrome (MERS)	1D64	Investigative	[1]
Severe acute respiratory syndrome (SARS)	1D65	Investigative	[1]

Therapeutic Class

Antiviral Agents

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
MERS-CoV spike glycoprotein S2' HR1 region (S S2'HR1)	TT854FJ	A0A140AYZ5_9BETC (888-1353)	Inhibitor	[1]
SARS-CoV spike glycoprotein S2' HR1 region (S S2'HR1)	TTXMITO	SPIKE_CVHSA (798-1255)	Inhibitor	[1]

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References

1	A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci Adv. 2019 Apr 10;5(4):eaav4580.