Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQ6P13)

Drug Name
Phenylphosphate Drug Info
Synonyms
Phenylphosphoric acid; Phenylphosphate; Phenyl dihydrogen phosphate; 701-64-4; Phosphoric acid, monophenyl ester; Phenyl phosphate; phenol phosphate; MONOPHENYL PHOSPHATE; monophenylphosphate; Phenolic phosphate; UNII-75M88J863E; EINECS 211-857-7; CHEMBL26128; CHEBI:37548; CMPQUABWPXYYSH-UHFFFAOYSA-N; 75M88J863E; HPS; phenoxyphosphonic acid; Phosphoric acid phenyl; 1o4o; ACMC-1BB8F; Dihydrogen Phenyl Phosphate; AC1L20DG; DSSTox_RID_80630; DSSTox_CID_24981; SCHEMBL20263; DSSTox_GSID_44981; Phosphoric Acid Phenyl Ester; Phenyl dihydroge
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
12793
ChEBI ID
CHEBI:37548
CAS Number
CAS 701-64-4
TTD Drug ID
DMQ6P13

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Proto-oncogene c-Src (SRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [2]
Bosutinib DMTI8YE Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [2]
SKI-758 DMQ8E9R Ischemia 8B10-8B11 Approved [3]
Herbimycin A DM6YWBF Solid tumour/cancer 2A00-2F9Z Approved [4]
AL3818 DM3WP0N Alveolar soft part sarcoma 2A60-2C35 Phase 3 [5]
CP-868596 DMZIM37 Gastrointestinal cancer 2C11 Phase 3 [5]
Masitinib DMRSNEU Amyotrophic lateral sclerosis 8B60.0 Phase 3 [6]
KX-01 DMF0NA9 Actinic keratosis EK90.0 Phase 3 [7]
Saracatinib DMBLHGP Hematologic tumour 2B33.Y Phase 2 [8]
TPX-0046 DMIVE67 Solid tumour/cancer 2A00-2F9Z Phase 1/2 [9]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Proto-oncogene c-Src (SRC) TT6PKBN SRC_HUMAN Inhibitor [1]

References

1 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
2 A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Curr Top Med Chem. 2007;7(14):1408-22.
3 Synthesis and Src kinase inhibitory activity of a series of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-furyl-3-quinolinecarbonitriles. J Med Chem. 2006 Dec 28;49(26):7868-76.
4 In vivo antitumor activity of herbimycin A, a tyrosine kinase inhibitor, targeted against BCR/ABL oncoprotein in mice bearing BCR/ABL-transfected cells. Leuk Res. 1994 Nov;18(11):867-73.
5 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
6 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
7 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
8 Novel dual Src/Abl inhibitors for hematologic and solid malignancies.Expert Opin Investig Drugs.2010 Aug;19(8):931-45.
9 Clinical pipeline report, company report or official report of Turning Point Therapeutics.