Details of the Drug Reposition

General Information of This Drug (ID: DMIZ6W2)

• Drug Name: Norfloxacin (DMIZ6W2)
• Synonyms: Baccidal; Barazan; Chibroxin; Fulgram; Lexinor; NFLX; Norflo; Norfloxacine; Norfloxacino; Norfloxacinum; Noroxin; Sebercim; Merck Brand of Norfloxacin; Norfloxacin Merck Brand; AM 0715; AM 715; AM0715; MK 0366; MK 366; MK0366; MK366; AM-0715; AM-715; Chibroxin (TN); Insensye (TN); MK-0366; MK-366; Norflohexal (TN); Norfloxacine [INN-French]; Norfloxacino [INN-Spanish]; Norfloxacinum [INN-Latin]; Norfocin (TN); Noroxin (TN); Nufloxib (TN); Roxin (TN); Utin (TN); Utinor (TN); Apo-Norflox (TN); Norfloxacin (JP15/USP/INN); Norfloxacin [USAN:BAN:INN:JAN]; Chibroxin, MK-366, Baccidal, Sebercim, Zoroxin, Norfloxacin; 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[1-piperazinyl]-3-quinoline-carboxylic acid; 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid; 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid; 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• Therapeutic Class: Antibiotics
• Drug Type: Small molecular drug

Information on Drug Reposition of This Drug

21 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Streptococcal pneumonia	DIS2EKMJ	N.A.	Approved	[1]
Staphylococcus aureus infection	DISK6PTH	N.A.	Approved	[1]
Staphylococcal pneumonia	DIS28ZSZ	N.A.	Approved	[1]
Pyelonephritis	DISAOX93	N.A.	Approved	[1]
Prostatitis	DISL8OGN	N.A.	Approved	[1]
Peritonitis	DISMCMLQ	N.A.	Approved	[1]
Mycoplasma pneumoniae pneumonia	DIS1AW2Z	N.A.	Approved	[1]
Malignant otitis externa caused by Pseudomonas aeruginosa	DIS5C8KP	N.A.	Approved	[1]
Endomyometritis	DIS9WIQU	N.A.	Approved	[1]
Chronic tubotympanic suppurative otitis media	DIS7R96F	N.A.	Approved	[1]
Chancroid	DISMVLOF	N.A.	Approved	[1]
Acute maxillary sinusitis	DISEUB5R	N.A.	Approved	[1]
Acute gonococcal cervicitis	DIS4LKDT	N.A.	Approved	[1]
Bacterial infection	DIS5QJ9S	1A00-1C4Z	Approved	[2]
Bacillary dysentery	DISFZHKN	1A02	Approved	[1]
Anthrax	DISFPT78	1B97	Approved	[1]
Bronchitis	DISBM6EQ	CA20	Approved	[1]
Pneumonia	DIS8EF3M	CA40	Approved	[1]
Cystitis	DIS2D4B9	GC00	Approved	[1]
Urinary tract infection	DISMT6UV	GC08	Approved	[1]
Traveler's diarrhea	DIS4R0UE	ME05.1	Approved	[1]

2 Withdrawn Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Peritonsillar abscess	DISZZXTZ	N.A.	Withdrawn	[3]
Acute gonococcal endometritis	DISZ8BW7	N.A.	Withdrawn	[4]

1 Discontinued in Phase 3 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Otitis externa	DISYCORK	AA00-AA13	Discontinued in Phase 3	[5]

4 Discontinued in Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Bacterial conjunctivitis	DIST79FU	N.A.	Discontinued in Phase 2	[6]
Rhinoscleroma	DISNSWVK	N.A.	Discontinued in Phase 2	[7]
Bacterial urinary tract infection	DISNNJTF	N.A.	Discontinued in Phase 2	[8]
Typhoid fever	DISP3NHR	1A07	Discontinued in Phase 2	[9]

2 Discontinued in Phase 1 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Escherichia coli infection	DISPP65M	1A03	Discontinued in Phase 1	[10]
Gonorrhea	DISQ5AO6	1A7Z	Discontinued in Phase 1	[11]

1 Investigative Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Pneumonia caused by chlamydia	DISX7CHR	N.A.	Investigative	[1]

References

• [1] Norfloxacin FDA Label
• [2] FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074690.
• [3] Feasibility Study of Short Term Fondaparinux (Arixtra) in Chemotherapy-Pretreated Ovarian Carcinoma Patients at High Risk of Progression
• [4] The Use of Domperidone for Gastroparesis
• [5] Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer
• [6] VELCADE,Rituximab,Cyclophosphamide and Decadron
• [7] Paclitaxel and Carboplatin or Temozolomide in Treating Patients With Stage IV Melanoma
• [8] Modafinil for Methamphetamine Dependence
• [9] Rasburicase and Allopurinol in Treating Patients With Hematologic Malignancies
• [10] ClinicalTrials.gov (NCT00096005) Tanespimycin and Bortezomib in Treating Patients With Advanced Solid Tumors or Lymphomas
• [11] Sorafenib and Thoracic Radiation for Patients With Non-Small Cell Lung Cancer