General Information of Disease (ID: DIS8EF3M)

Disease Name Pneumonia
Synonyms acute pneumonia
Disease Class CA40: Pneumonia
Definition
An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.
Disease Hierarchy
DIS88E0K: Pneumonitis
DIS7OJYM: Respiratory tract infection
DIS8EF3M: Pneumonia
ICD Code
ICD-11
ICD-11: CA40
Expand ICD-11
'CA40.Z
Disease Identifiers
MONDO ID
MONDO_0005249
MESH ID
D011014
UMLS CUI
C0032285
MedGen ID
10813
HPO ID
HP:0002090
SNOMED CT ID
233604007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 21 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Amphotericin B DMTAJQE Approved Small molecular drug [1]
Cefaclor DMJXDGC Approved Small molecular drug [2]
Cefalotin DMVYSLE Approved Small molecular drug [3]
Cefamandole DMNEXZF Approved Small molecular drug [4]
Cefmetazole DM42W1B Approved Small molecular drug [5]
Cefonicid DMTX2BH Approved Small molecular drug [6]
Cefradine DMUNSWV Approved Small molecular drug [7]
Ceftizoxime DM3VOGS Approved Small molecular drug [8]
Cephapirin DMV2JNY Approved Small molecular drug [9]
Demeclocycline DMZEPFJ Approved Small molecular drug [10]
Dirithromycin DM0D9YJ Approved Small molecular drug [11]
Eptifibatide DMQXTJS Approved Small molecular drug [12]
Fusidic Acid DMWVCF3 Approved Small molecular drug [13]
Minocycline DMVN5OH Approved Small molecular drug [14]
Nitric Oxide DM1RBYG Approved Small molecular drug [15]
Norfloxacin DMIZ6W2 Approved Small molecular drug [16]
Ofloxacin DM0VQN3 Approved Small molecular drug [17]
Oxytetracycline DMOVH1M Approved Small molecular drug [18]
Simvastatin DM30SGU Approved Small molecular drug [19]
Sparfloxacin DMB4HCT Approved Small molecular drug [20]
Tetracycline DMZA017 Approved Small molecular drug [21]
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⏷ Show the Full List of 21 Drug(s)
This Disease is Treated as An Indication in 8 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
AR-301 DM2YQK8 Phase 3 Antibody [22]
Cethromycin DMIGX84 Phase 3 Small molecular drug [23]
Iclaprim DM7YNV9 Phase 3 Small molecular drug [24]
Zabofloxacin DMEY1F3 Phase 3 Small molecular drug [25]
AP-301-IH DM3ICYL Phase 2 NA [27]
Radezolid DMOI9EL Phase 2 NA [28]
Streptococcus pneumoniae vaccine DM3136S Phase 1 NA [29]
TP-271 DM3PJSE Phase 1 Small molecular drug [30]
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⏷ Show the Full List of 8 Drug(s)
This Disease is Treated as An Indication in 1 Drugs in Phase 2 Trial
Drug Name Drug ID Highest Status Drug Type REF
Heparin DM4ZP3W Phase 2/3 Trial Small molecular drug [26]
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This Disease is Treated as An Indication in 2 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Clinafloxacin DM6F8L5 Terminated Small molecular drug [31]
PGCvax DMKGYB9 Terminated NA [32]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 1 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
SD-102 DM0JRK1 Investigative NA [33]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 231 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ACE2 TTUI5H7 Limited Biomarker [34]
ACKR1 TTKY2NS Limited Biomarker [35]
ATP4A TTF1QVM Limited Biomarker [36]
CD248 TTYJWT7 Limited Biomarker [37]
CFD TT8D13I Limited Biomarker [38]
CFP TTLA0VS Limited Biomarker [38]
CPS1 TT42M75 Limited Biomarker [39]
ELANE TTPLTSQ Limited Biomarker [40]
F2RL1 TTQR74A Limited Biomarker [41]
FGG TTR31L7 Limited Altered Expression [42]
ICAM1 TTA1L39 Limited Altered Expression [43]
IL20 TTNZMY2 Limited Biomarker [44]
ITGAE TTH0Z37 Limited Biomarker [45]
LAIR1 TTSI7A8 Limited Biomarker [46]
LCT TTA0OSE Limited Biomarker [47]
LTB4R2 TTVJX54 Limited Biomarker [48]
MAP3K14 TT4LIAC Limited Genetic Variation [49]
NOD1 TTYSRXM Limited Altered Expression [50]
P2RY12 TTZ1DT0 Limited Biomarker [51]
PARP1 TTVDSZ0 Limited Biomarker [52]
PLA2G1B TT9V5JH Limited Altered Expression [53]
PREP TTNGKET Limited Biomarker [54]
SELPLG TTS5K8U Limited Altered Expression [55]
ST8SIA4 TTDP8YM Limited Biomarker [56]
TBXA2R TT2O84V Limited Biomarker [57]
TICAM1 TT2GQT6 Limited Biomarker [58]
TIRAP TTKU0LS Limited Biomarker [59]
ANGPT1 TTWNQ1T Disputed Biomarker [60]
AOC1 TTM3B5R Disputed Biomarker [61]
CLCA1 TT3AF4R Disputed Biomarker [62]
CXCL10 TTQOVYA Disputed Altered Expression [63]
CYBB TT5T8MR Disputed Biomarker [64]
DHPS TTBO2A9 Disputed Genetic Variation [65]
GAA TTLPC70 Disputed CausalMutation [66]
GP6 TTTJUVZ Disputed Biomarker [67]
IL36G TT8SLDN Disputed Altered Expression [68]
MMP12 TTXZ0KQ Disputed Biomarker [69]
NLRP3 TT4EN8X Disputed Biomarker [70]
SCGB1A1 TTONPVW Disputed Biomarker [71]
SERPINE1 TTTO43N Disputed Biomarker [72]
TLR8 TT8CWFK Disputed Biomarker [73]
TREM1 TTHZQP0 Disputed Biomarker [74]
C3 TTJGY7A moderate Biomarker [75]
CCL22 TTBTWI1 moderate Biomarker [76]
CXCL2 TTZF0K2 moderate Biomarker [77]
EPHX2 TT7WVHI moderate Biomarker [78]
FDPS TTIKWV4 moderate Biomarker [79]
FES TTLBY21 moderate Biomarker [79]
IRAK3 TTBPJOK moderate Biomarker [80]
ITGA4 TTJMF9P moderate Therapeutic [81]
REG3A TTL4H8N moderate Biomarker [82]
SLC11A2 TT2IS7P moderate Biomarker [83]
SMPD2 TTE5VI6 moderate Biomarker [84]
ABHD6 TTSINOV Strong Biomarker [85]
ADA TTLP57V Strong Altered Expression [86]
ADAM8 TTQWYMD Strong Biomarker [87]
ADORA2B TTNE7KG Strong Biomarker [88]
ADORA3 TTJFY5U Strong Biomarker [89]
ADRB2 TTG8ZWP Strong Biomarker [90]
AGRP TT4DE1O Strong Biomarker [91]
AHR TT037IE Strong Biomarker [92]
AIMP2 TTXWHGF Strong Biomarker [93]
ALOX12 TT12ABZ Strong Biomarker [94]
ALOX15 TTN9T81 Strong Biomarker [94]
ANK1 TTKFPMH Strong Biomarker [95]
AOAH TT2EJXQ Strong Biomarker [96]
AOC3 TT7HC21 Strong Biomarker [97]
ARG1 TT7ZQEV Strong Biomarker [98]
BDKRB1 TTG5QIA Strong Biomarker [99]
BMP1 TT0L58T Strong Biomarker [100]
BTK TTGM6VW Strong Biomarker [101]
C3AR1 TTI6B3F Strong Altered Expression [102]
CAMP TTULOB6 Strong Altered Expression [103]
CCL11 TTCF05Y Strong Altered Expression [104]
CCL17 TTMPHAE Strong Biomarker [105]
CCL2 TTNAY0P Strong Biomarker [106]
CCL20 TT2XAZY Strong Biomarker [105]
CCL3 TT8I4WB Strong Biomarker [107]
CCR1 TTC24WT Strong Biomarker [105]
CCR2 TTFZYTO Strong Biomarker [108]
CCR4 TT7HQD0 Strong Biomarker [109]
CCR6 TTFDB30 Strong Biomarker [105]
CCR8 TTE836A Strong Biomarker [110]
CCR9 TTIPS8B Strong Biomarker [105]
CD2 TTJDUNO Strong Genetic Variation [111]
CD276 TT6CQUM Strong Biomarker [112]
CD86 TT53XHB Strong Biomarker [113]
CFI TT6ATLX Strong Biomarker [114]
CLEC6A TTQ02HK Strong Biomarker [115]
CLEC9A TTGUSRB Strong Biomarker [116]
CMKLR1 TT4UGZL Strong Biomarker [117]
CR2 TT0HUN7 Strong Genetic Variation [118]
CRK TTFEUYR Strong Biomarker [93]
CRLF2 TTRMZ0N Strong Altered Expression [119]
CSF1 TT0IQER Strong Genetic Variation [120]
CSF2 TTNYZG2 Strong Biomarker [91]
CTSA TT5NILS Strong Altered Expression [121]
CTSG TTQAJF1 Strong Biomarker [122]
CX3CL1 TT1OFBQ Strong Biomarker [105]
CXCL1 TTLK1RW Strong Biomarker [123]
CXCL13 TT0NIZ1 Strong Altered Expression [124]
CXCL9 TTWE5PB Strong Biomarker [105]
CXCR2 TT30C9G Strong Altered Expression [125]
CXCR3 TT1UCIJ Strong Biomarker [105]
CYSLTR1 TTGKOY9 Strong Biomarker [126]
DEFB4A TTIVY12 Strong Biomarker [127]
DNASE1 TTYWGOJ Strong Biomarker [128]
ECE1 TTQ9RYT Strong Biomarker [129]
EGR1 TTE8LGD Strong Therapeutic [130]
ENTPD1 TTYM8DJ Strong Altered Expression [131]
F2R TTL935N Strong Biomarker [132]
F8 TT1290U Strong Biomarker [133]
FABP4 TTHWMFZ Strong Biomarker [123]
FABP5 TTNT2S6 Strong Biomarker [134]
FCGR1A TTZK4I3 Strong Altered Expression [135]
FCGR2A TTXT21W Strong Genetic Variation [136]
FCGR2B TT5RWKQ Strong Biomarker [137]
FER TTRA9G0 Strong Biomarker [138]
FOXP3 TT1X3QF Strong Biomarker [139]
FPR1 TT5Y4EM Strong Biomarker [140]
FPR2 TTOJ1NF Strong Biomarker [141]
GCLM TTNFESW Strong Altered Expression [142]
GHRHR TTG4R8V Strong Biomarker [143]
GLA TTIS03D Strong Biomarker [144]
HMOX1 TTI6V2A Strong Biomarker [145]
HSD11B1 TTN7BL9 Strong Altered Expression [146]
ICOS TTE5VP6 Strong Biomarker [147]
ICOSLG TTB9Z8R Strong Biomarker [148]
ID2 TTW8A5N Strong Genetic Variation [149]
IFNB1 TT4TZ8J Strong Biomarker [150]
IFNG TT93WF5 Strong Altered Expression [151]
IKBKB TTJ3E9X Strong Biomarker [152]
IL10RB TTJTRMK Strong Biomarker [153]
IL16 TTW4R0B Strong Biomarker [154]
IL17A TTG0MT6 Strong Biomarker [155]
IL17D TTC5LTG Strong Biomarker [156]
IL18 TTRICUF Strong Biomarker [72]
IL19 TT87RWS Strong Biomarker [157]
IL1R1 TTWOTEA Strong Biomarker [105]
IL1R2 TT51DEV Strong Biomarker [105]
IL1RN TT6GSR3 Strong Genetic Variation [158]
IL22 TTLDX4N Strong Biomarker [159]
IL25 TTVMO5W Strong Biomarker [160]
IL2RB TT9721Y Strong Biomarker [105]
IL31 TT1RJXK Strong Biomarker [161]
IL31RA TT9HPX0 Strong Genetic Variation [161]
IL33 TT5MD4P Strong Biomarker [162]
IL37 TTQTX98 Strong Biomarker [163]
IL4 TTLGTKB Strong Altered Expression [164]
IL5RA TTXH9AD Strong Biomarker [105]
IL6 TTT1V78 Strong Altered Expression [165]
IL7 TT8FRMO Strong Biomarker [166]
IL9 TT0JTFD Strong Altered Expression [167]
ITCH TT5SEWD Strong Biomarker [168]
ITGB2 TTIJWR7 Strong Biomarker [105]
JAK3 TTT7PJU Strong Biomarker [169]
KNG1 TTDJ4MY Strong Biomarker [170]
LILRB4 TTREOKA Strong Biomarker [171]
LNPEP TTY2KP7 Strong Biomarker [172]
LY96 TT8S9AV Strong Biomarker [173]
MAP3K19 TTRHJA3 Strong Biomarker [174]
MAP3K7 TTJQT60 Strong Biomarker [175]
MARK2 TTAJ45Y Strong Biomarker [176]
MASP2 TTR01E9 Strong Biomarker [136]
MBL2 TTMQDZ5 Strong Biomarker [177]
MMP8 TTGA1IV Strong Altered Expression [107]
MUC5AC TTEL90S Strong Genetic Variation [178]
MYLK TT18ETS Strong Biomarker [179]
NAAA TTMN4HY Strong Biomarker [180]
NAMPT TTD1WIG Strong Genetic Variation [181]
NFKB1 TTUIZKC Strong Biomarker [182]
NFKB2 TTKLNRV Strong Altered Expression [183]
NOD2 TTYPUHA Strong Altered Expression [184]
NPR1 TTM9IYA Strong Biomarker [185]
OSM TTIVXSE Strong Biomarker [186]
P2RY6 TTNVSKA Strong Genetic Variation [187]
PDE4A TTZ97H5 Strong Altered Expression [188]
PDE7A TT1BC3A Strong Biomarker [189]
PF4 TTSG7Q5 Strong Biomarker [190]
PIKFYVE TTA4M1N Strong Biomarker [191]
PLD1 TT3T17P Strong Biomarker [192]
PLD2 TTRLMKF Strong Biomarker [192]
PMEL TT8MK59 Strong Altered Expression [183]
POMC TT21AKM Strong Biomarker [193]
PRCP TTTJZ4M Strong Biomarker [100]
PRDX4 TTPBL9I Strong Biomarker [194]
PRKCD TT7A1BO Strong Biomarker [195]
PRMT1 TTVOJAI Strong Biomarker [196]
PROC TTZUXYS Strong Biomarker [197]
PTAFR TTQL5VC Strong Biomarker [198]
PTGER3 TTPNGDE Strong Biomarker [199]
ROS1 TTSZ6Y3 Strong Biomarker [200]
S1PR2 TTVSMOH Strong Biomarker [201]
SDC2 TT5H2F0 Strong Biomarker [202]
SELL TT2IYXF Strong Biomarker [203]
SGPL1 TT618Q2 Strong Altered Expression [204]
SIRT1 TTUF2HO Strong Biomarker [205]
SLC52A2 TT6TKEN Strong Biomarker [176]
SLC5A1 TT2UE56 Strong Genetic Variation [206]
SLC8A1 TTCF82X Strong Genetic Variation [207]
SOCS3 TTI0ME6 Strong Biomarker [208]
SPP1 TT8ME6I Strong Biomarker [209]
STK39 TTYQTIU Strong Biomarker [210]
TBX21 TTNF9PH Strong Altered Expression [211]
TFPI TT068JH Strong Biomarker [212]
TLR2 TTY7ZHS Strong Biomarker [213]
TLR3 TTD24Y0 Strong Altered Expression [214]
TLR4 TTISGCA Strong Biomarker [215]
TLR5 TTCXP8J Strong Biomarker [216]
TNFRSF1B TT63WSF Strong Biomarker [217]
TNFRSF25 TTDV6BQ Strong Biomarker [218]
TRPA1 TTELV3W Strong Biomarker [95]
TRPM8 TTXDKTO Strong Biomarker [219]
TRPV2 TTBECWA Strong Biomarker [220]
TSLP TTHMW3T Strong Biomarker [119]
USP13 TTVJIO2 Strong Biomarker [221]
VSIR TT51SK8 Strong Biomarker [222]
WWP2 TT6TU05 Strong Biomarker [223]
AGT TT5C0UB Definitive Biomarker [224]
CASP1 TTCQIBE Definitive Biomarker [225]
CD40LG TTIJP3Q Definitive Genetic Variation [226]
CD83 TTT9MRQ Definitive Biomarker [227]
FCAR TTGUJAO Definitive Biomarker [228]
IL5 TTPREZD Definitive Altered Expression [164]
MPO TTVCZPI Definitive Biomarker [229]
POR TTOQ9GZ Definitive Biomarker [230]
PTGDR2 TTQDMX5 Definitive Biomarker [231]
SFTPD TTGLMU7 Definitive Altered Expression [232]
SSRP1 TTETDKQ Definitive Genetic Variation [233]
TNFRSF1A TTG043C Definitive Biomarker [234]
UGCG TTPHEX3 Definitive Genetic Variation [235]
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⏷ Show the Full List of 231 DTT(s)
This Disease Is Related to 4 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC9A6 DTN0JXW Disputed Genetic Variation [236]
ABCA3 DT2T6VQ Strong Biomarker [237]
SLC12A2 DTHKL3Q Strong Biomarker [210]
SLC2A10 DT3BI6S Definitive Biomarker [238]
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This Disease Is Related to 7 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
SMOX DEOH5V3 Limited Altered Expression [239]
BAAT DERA3OF Disputed Biomarker [240]
AOC2 DE8DP90 Strong Biomarker [97]
CYP2A13 DEXZA9U Strong Altered Expression [241]
GCLC DESYL1F Strong Genetic Variation [235]
PGPEP1 DEVDR46 Strong Biomarker [100]
PTGDS DER3H9C Strong Biomarker [242]
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⏷ Show the Full List of 7 DME(s)
This Disease Is Related to 225 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ATXN7 OTL3YF1H Limited Biomarker [243]
CCDC22 OT1A1ZXH Limited Genetic Variation [244]
CCL24 OT9LGHV0 Limited Biomarker [245]
CD5L OTPY4WQR Limited Biomarker [246]
CDK15 OT8S67QS Limited Genetic Variation [49]
CDK16 OTUBXIIT Limited Genetic Variation [49]
CELF2 OTLJJ4VT Limited Genetic Variation [247]
CILK1 OTWOYEYP Limited Genetic Variation [49]
CLDN2 OTRF3D6Y Limited Altered Expression [248]
COLEC11 OT4GC46Y Limited Biomarker [249]
CRLS1 OT7XNL0K Limited Biomarker [250]
CRPPA OTC85K8Q Limited Biomarker [251]
DCDC2 OTSUFH1H Limited Biomarker [252]
DPT OTINRFC7 Limited Biomarker [253]
DUOXA1 OTNG3HH4 Limited Biomarker [251]
FBXO15 OTJHEFE5 Limited Biomarker [250]
FCN2 OTTHJBKZ Limited Genetic Variation [254]
GIPC1 OTXLVCPJ Limited Biomarker [251]
GPR15 OTK8674M Limited Biomarker [255]
GPRC5A OTPOCWR7 Limited Altered Expression [256]
HCCS OTQE88BE Limited Biomarker [257]
IBTK OTB2GM4G Limited Biomarker [258]
JAM3 OTX0F9QL Limited Altered Expression [259]
MORF4L1 OTEA6FYJ Limited Altered Expression [260]
MOXD1 OTUMCWRN Limited Biomarker [37]
MPRIP OT5FV5NS Limited Biomarker [261]
MS4A2 OTMCAS2D Limited Biomarker [262]
MYO18A OT2YPT7O Limited Biomarker [263]
NCF2 OTAUW7L2 Limited Biomarker [264]
PES1 OTMZK7XE Limited Biomarker [265]
PGLYRP4 OTI115BR Limited Biomarker [266]
PIWIL4 OTDA9MY0 Limited Altered Expression [267]
PLEKHA7 OTNUMAZ0 Limited Biomarker [268]
PPP6R2 OTERHESI Limited Biomarker [269]
PRKACG OTKOQYF8 Limited Genetic Variation [49]
PRSS2 OTOMVUWL Limited Biomarker [270]
SIX2 OTYOVGSC Limited Genetic Variation [271]
TLK1 OTICTXI8 Limited Genetic Variation [49]
TRIM69 OTTEGTRD Limited Biomarker [58]
AIDA OTMRLWGT Disputed Biomarker [272]
AMBP OTLU8GU8 Disputed Genetic Variation [273]
DECR1 OTCDIR6X Disputed Genetic Variation [274]
DNAJC5 OTCZDXAL Disputed Biomarker [275]
HTRA3 OTXJ0H4X Disputed Altered Expression [276]
MCEE OTTJP3GM Disputed Biomarker [277]
MEIS1 OTH9DKAD Disputed Biomarker [278]
MPP1 OTA2ENZQ Disputed Biomarker [234]
NLRP6 OTEREN4W Disputed Biomarker [279]
PIK3R3 OTXGJ8N1 Disputed Biomarker [234]
POLG2 OTDBMZJB Disputed Biomarker [234]
PSMD12 OTWICA51 Disputed Biomarker [234]
RAC2 OTAOHFNH Disputed Biomarker [280]
RBM8A OT5SR6G0 Disputed Biomarker [281]
SAA2 OTYAVJWG Disputed Biomarker [282]
SARS1 OTFKXQ1O Disputed Biomarker [283]
SARS2 OTU4T99W Disputed Biomarker [283]
SFTPB OTOHS07E Disputed Genetic Variation [284]
BPIFA1 OTQFD2J5 moderate Biomarker [285]
C4BPB OTJ70B0K moderate Altered Expression [286]
HPR OTXSC9UB moderate Altered Expression [287]
IL22RA2 OTGOFDCY moderate Biomarker [159]
MPPE1 OTINBJVE moderate Biomarker [288]
OSBP2 OTDGLB4J moderate Biomarker [289]
SH2D1A OTLU49I5 moderate Biomarker [290]
ABCF1 OT6Q079J Strong Biomarker [105]
AHSA1 OTC7AFHT Strong Biomarker [93]
ALDH7A1 OTV57BZD Strong Biomarker [291]
AQP5 OT77GBY8 Strong Altered Expression [292]
AREL1 OTSYV9R3 Strong Biomarker [293]
ARHGEF5 OTUVGFT9 Strong Biomarker [294]
ARID3B OTUP9MS4 Strong Genetic Variation [295]
ARIH1 OTO3XDR2 Strong Biomarker [281]
ASCC2 OT3B204T Strong Altered Expression [183]
BST1 OTAV5SE7 Strong Biomarker [296]
BTRC OT2EZDGR Strong Biomarker [297]
BUD23 OTJS7VU3 Strong Biomarker [298]
CAP1 OTYM8A2N Strong Biomarker [172]
CARD10 OT2RPM4I Strong Biomarker [299]
CARD11 OTRCTLYC Strong Biomarker [300]
CCL13 OTNX0JD0 Strong Altered Expression [301]
CCL19 OTQ2UJMH Strong Biomarker [302]
CCL26 OT2B7HR9 Strong Altered Expression [303]
CCL4 OT6B8P25 Strong Biomarker [105]
CCL7 OTDIS99H Strong Biomarker [105]
CCL8 OTCTWYN8 Strong Biomarker [110]
CEMIP OTK80FYN Strong Biomarker [304]
CENPJ OTZCQZN5 Strong Biomarker [305]
CFAP97 OT0RSQO4 Strong Biomarker [306]
CFHR1 OT72R16T Strong Biomarker [307]
CIRBP OTXWTPBL Strong Biomarker [308]
CLEC1B OTO38TRG Strong Biomarker [67]
CLEC7A OTRTBH27 Strong Biomarker [309]
CXCL5 OTZOUPCA Strong Altered Expression [310]
CYTB OTAHB98A Strong Biomarker [311]
DCD OTV5PBGJ Strong Genetic Variation [312]
DDT OTF5HTYL Strong Altered Expression [313]
DROSHA OTCE68KZ Strong Biomarker [314]
EMP1 OTSZHUHQ Strong Genetic Variation [315]
EPG5 OT3P5HQD Strong Biomarker [316]
ESAM OTF518AI Strong Altered Expression [317]
EXO1 OTI87RS5 Strong Biomarker [318]
FEV OTYEC4IR Strong Biomarker [319]
FLT3LG OTU0YGC4 Strong Altered Expression [320]
FOSB OTW6C05J Strong Biomarker [321]
FOXD1 OT80PRHS Strong Genetic Variation [322]
FOXF1 OT2CJZ5K Strong Biomarker [323]
FOXN1 OTE80D6I Strong Biomarker [324]
FXYD5 OT81DIOD Strong Biomarker [325]
GGPS1 OTVEHG28 Strong Biomarker [326]
GRAP2 OTS5NIZ3 Strong Biomarker [93]
GSDMB OTWA7P10 Strong Biomarker [327]
GTF2H4 OTPD1DIU Strong Altered Expression [183]
HACD1 OTEC7EP7 Strong Biomarker [172]
HAVCR1 OT184CRZ Strong Biomarker [294]
HLA-E OTX1CTFB Strong Altered Expression [328]
HPX OT14T7Q1 Strong Biomarker [329]
HRG OTPLUFOG Strong Biomarker [330]
HSH2D OTOGB2BR Strong Biomarker [117]
HSPA14 OTZCA5LK Strong Biomarker [331]
HSPA1A OTKGIE76 Strong Biomarker [194]
IKBKG OTNWJWSD Strong Biomarker [332]
IL17B OTS86H50 Strong Biomarker [44]
IL17C OTKXIVNQ Strong Biomarker [333]
IL17RE OTMFTNLS Strong Biomarker [333]
IL20RA OTSIVBVS Strong Biomarker [157]
IL27 OTIS3OF8 Strong Biomarker [156]
IL27RA OTSQBAKI Strong Altered Expression [334]
IL6ST OT1N9C70 Strong Biomarker [335]
IMMT OTBDSLE7 Strong Biomarker [336]
INSRR OT3F75WA Strong Genetic Variation [337]
ITGAX OTOGIMHE Strong Altered Expression [175]
JTB OT314JB6 Strong Biomarker [338]
JUNB OTG2JXV5 Strong Biomarker [321]
JUND OTNKACJD Strong Biomarker [321]
KCNK6 OTCY281R Strong Biomarker [339]
KLF10 OT4F4UGS Strong Biomarker [185]
KLHL2 OT1NG8V7 Strong Altered Expression [340]
LAMA1 OTQZMP86 Strong Genetic Variation [341]
LCLAT1 OTCOP0JN Strong Altered Expression [342]
LSP1 OTSPSIFO Strong Biomarker [343]
MARCHF1 OTI2EYO6 Strong Genetic Variation [344]
MLKL OTDSLC81 Strong Biomarker [261]
MMP28 OTHQZXM1 Strong Biomarker [345]
MTSS2 OTKMNSBF Strong Biomarker [346]
MUC2 OT3X4QVX Strong Altered Expression [248]
MYDGF OT9HRPL6 Strong Biomarker [156]
NBEAL2 OTMCAXWR Strong Genetic Variation [347]
NBR1 OTVRL7J9 Strong Biomarker [348]
NCF4 OTX007YL Strong Biomarker [207]
NELFCD OTOLTZPU Strong Altered Expression [349]
NEO1 OTGJ1997 Strong Biomarker [350]
NFATC2 OTK5T6HZ Strong Altered Expression [351]
NFATC3 OTYOORME Strong Biomarker [352]
NINJ1 OTLRZ1EU Strong Biomarker [353]
NKX2-1 OTCMEJTA Strong Biomarker [354]
NLRC4 OTAIA3NA Strong Biomarker [355]
NLRP12 OTGR132Z Strong Biomarker [356]
NMU OTW9X7BQ Strong Biomarker [357]
NR2C2 OTDZWVOJ Strong Altered Expression [175]
OAS3 OT6E5FYS Strong Altered Expression [183]
OR10A4 OTYYB8SY Strong Biomarker [358]
P4HB OTTYNYPF Strong Altered Expression [359]
PCP4 OTM1XXYX Strong Genetic Variation [360]
PGAM5 OT6Q5M0C Strong Biomarker [361]
PHLPP2 OTXB1OUI Strong Biomarker [291]
PI3 OT47MTC3 Strong Altered Expression [362]
PIAS1 OTZVAHZI Strong Altered Expression [307]
PLA2G5 OTQRSKCZ Strong Biomarker [363]
PLCL1 OTJL2C79 Strong Biomarker [310]
PLXNC1 OTJ5XKYY Strong Biomarker [364]
POLDIP2 OT8SZSJ6 Strong Biomarker [93]
PPM1K OTNZ4N4E Strong Genetic Variation [295]
PPP1R11 OTSHYPPW Strong Biomarker [365]
PROCR OTRHED17 Strong Biomarker [176]
RAG1 OTV131E4 Strong Biomarker [366]
RAP1B OTHEIIMM Strong Biomarker [367]
RETNLB OT9JJQQQ Strong Biomarker [368]
RIPK3 OTL1D484 Strong Biomarker [74]
RNF19A OTKWCV80 Strong Biomarker [93]
RNGTT OT59E0KX Strong Genetic Variation [312]
RPS19 OTBKGP48 Strong Biomarker [369]
RRBP1 OT4ZTPTM Strong Biomarker [370]
SART3 OTC1AM7S Strong Altered Expression [183]
SCAF1 OT16TM3N Strong Biomarker [371]
SCAF11 OTX59D0X Strong Biomarker [355]
SCGB3A2 OTB63PHR Strong Biomarker [372]
SDC4 OTKUVUGZ Strong Biomarker [373]
SEMA4A OT8901H3 Strong Biomarker [374]
SEMA7A OT0ZJK64 Strong Biomarker [375]
SERPINB1 OT5RDUFO Strong Biomarker [376]
SERPINB6 OT7G55IK Strong Biomarker [172]
SFRP5 OTLCVVSH Strong Biomarker [377]
SFTPA1 OT87XL1U Strong Altered Expression [232]
SFTPA2 OT6SFOMU Strong Altered Expression [232]
SFTPC OTIZJD09 Strong Biomarker [378]
SIGIRR OTNC3XFD Strong Biomarker [221]
SIGLEC8 OTQ5TRRV Strong Altered Expression [379]
SMC3 OTWGFRHD Strong Genetic Variation [312]
SND1 OTT734JN Strong Altered Expression [183]
SOCS2 OTBPNKJQ Strong Biomarker [293]
SORBS1 OTWH8762 Strong Biomarker [172]
SPESP1 OTWXKKTJ Strong Biomarker [380]
SULF1 OTJCNCO0 Strong Biomarker [381]
TIMELESS OTD8DCBJ Strong Biomarker [294]
TM7SF2 OTILU5S7 Strong Biomarker [60]
TNFAIP8L2 OTII0RM0 Strong Altered Expression [382]
TRAF1 OTTLM5RU Strong Biomarker [383]
TRAF3IP2 OTLLZERL Strong Biomarker [384]
TRAF5 OTSBTLO0 Strong Biomarker [186]
TRIM65 OTSQTK3A Strong Biomarker [385]
TTF1 OT4K90WD Strong Biomarker [354]
BATF2 OT4XBZC9 Definitive Biomarker [386]
COL4A5 OTHG60RE Definitive Biomarker [238]
FUT2 OTLXM6WI Definitive Genetic Variation [387]
GZMA OT43R33L Definitive Altered Expression [135]
HLA-DQA2 OT1DH0N9 Definitive Biomarker [388]
MYH11 OTVNVWY3 Definitive Biomarker [389]
PIGW OTT9SMTF Definitive Biomarker [390]
RIT1 OTVNOGOH Definitive Genetic Variation [391]
RNF19B OTYCWKBP Definitive Biomarker [392]
RTL1 OTOT33IM Definitive Biomarker [393]
RTN3 OTGZ51QF Definitive Biomarker [394]
SAFB OTGRV2LW Definitive Biomarker [394]
SETMAR OTE2MIMZ Definitive Biomarker [393]
SIVA1 OTDT0XZK Definitive Altered Expression [395]
------------------------------------------------------------------------------------
⏷ Show the Full List of 225 DOT(s)

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116 CLEC9A modulates macrophage-mediated neutrophil recruitment in response to heat-killed Mycobacterium tuberculosis H37Ra.PLoS One. 2017 Oct 24;12(10):e0186780. doi: 10.1371/journal.pone.0186780. eCollection 2017.
117 Specialized Pro-Resolving Lipid Mediators Regulate Ozone-Induced Pulmonary and Systemic Inflammation.Toxicol Sci. 2018 Jun 1;163(2):466-477. doi: 10.1093/toxsci/kfy040.
118 Pediatric hyperimmunoglobulin E syndrome: A case series of 4 children in China.Medicine (Baltimore). 2018 Apr;97(14):e0215. doi: 10.1097/MD.0000000000010215.
119 IL-7R Expression Regulates Murine Dendritic Cell Sensitivity to Thymic Stromal Lymphopoietin.J Immunol. 2017 May 15;198(10):3909-3918. doi: 10.4049/jimmunol.1600753. Epub 2017 Apr 12.
120 Colony-stimulating factor 1 and its receptor are new potential therapeutic targets for allergic asthma.Allergy. 2020 Feb;75(2):357-369. doi: 10.1111/all.14011. Epub 2019 Oct 11.
121 A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome and Trigger Inflammation.Cell Host Microbe. 2016 May 11;19(5):664-74. doi: 10.1016/j.chom.2016.04.004. Epub 2016 Apr 28.
122 Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment.Circulation. 2016 Oct 18;134(16):1176-1188. doi: 10.1161/CIRCULATIONAHA.116.024790. Epub 2016 Sep 22.
123 Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia.FASEB J. 2019 Mar;33(3):3562-3574. doi: 10.1096/fj.201802002R. Epub 2018 Nov 21.
124 Evaluation of the Diagnostic Efficacies of Serological Markers KL-6, SP-A, SP-D, CCL2, and CXCL13 in Idiopathic Interstitial Pneumonia.Respiration. 2019;98(6):534-545. doi: 10.1159/000503689. Epub 2019 Oct 30.
125 p53- and PAI-1-mediated induction of C-X-C chemokines and CXCR2: importance in pulmonary inflammation due to cigarette smoke exposure.Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15;310(6):L496-506. doi: 10.1152/ajplung.00290.2015. Epub 2016 Jan 8.
126 Leukotriene C4 Potentiates IL-33-Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation.J Immunol. 2017 Aug 1;199(3):1096-1104. doi: 10.4049/jimmunol.1601569. Epub 2017 Jun 30.
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128 STING-dependent sensing of self-DNA drives silica-induced lung inflammation.Nat Commun. 2018 Dec 6;9(1):5226. doi: 10.1038/s41467-018-07425-1.
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