Details of the Drug

General Information of Drug (ID: DMNFCXW)

Drug Name
THIOCTIC ACID
Synonyms
dl-Thioctic acid; thioctic acid; 1077-28-7; 5-(1,2-Dithiolan-3-yl)pentanoic acid; DL-alpha-Lipoic acid; 1,2-dithiolane-3-pentanoic acid; Thioctacid; 6,8-Thioctic acid; 6-Thioctic acid; Lipothion; Biletan; dl-Lipoic acid; Tioctacid; Thioctsan; Liposan; Rac-lipoate; 1,2-Dithiolane-3-valeric acid; DL-6,8-Thioctic acid; alpha-Liponsaeure; DL-6-Thioctic acid; alpha-liponic acid; Thioktsaeure; Tioctidasi; (RS)-Lipoic acid; 6,8-Dithiooctanoic acid; espa-lipon; Thioctic acid dl-form; 62-46-4
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Affected Organisms
Humans and other mammals
ATC Code
A16AX01: THIOCTIC ACID
A16AX: Various alimentary tract and metabolism products
A16A: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A: ALIMENTARY TRACT AND METABOLISM
A16AX01: THIOCTIC ACID
A16AX: Various alimentary tract and metabolism products
A16A: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A: ALIMENTARY TRACT AND METABOLISM
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 206.3
Logarithm of the Partition Coefficient (xlogp) 1.7
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
ADMET Property
Clearance
The drug present in the plasma can be removed from the body at the rate of 11.5 mL/min/kg [2]
Half-life
The concentration or amount of drug in body reduced by one-half in 0.21 hours [2]
Vd
Fluid volume that would be required to contain the amount of drug present in the body at the same concentration as in the plasma 0.1 L/kg [2]
Chemical Identifiers
Formula
C8H14O2S2
IUPAC Name
5-(dithiolan-3-yl)pentanoic acid
Canonical SMILES
C1CSSC1CCCCC(=O)O
InChI
InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
InChIKey
AGBQKNBQESQNJD-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
864
ChEBI ID
CHEBI:16494
CAS Number
1077-28-7
UNII
VLL71EBS9Z
DrugBank ID
DB00166
TTD ID
D0P6PQ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Acetylcholinesterase (AChE) TT1RS9F ACES_HUMAN Inhibitor [3]
Prostaglandin G/H synthase 2 (COX-2) TTVKILB PGH2_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Drug Response [4]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [4]
Catalase (CAT) OTHEBX9R CATA_HUMAN Gene/Protein Processing [5]
Epididymal secretory glutathione peroxidase (GPX5) OTQMMNNT GPX5_HUMAN Gene/Protein Processing [5]
Glutamate--cysteine ligase catalytic subunit (GCLC) OTESDI4D GSH1_HUMAN Gene/Protein Processing [6]
Glutamate--cysteine ligase regulatory subunit (GCLM) OT6CP234 GSH0_HUMAN Gene/Protein Processing [6]
Glutathione peroxidase 1 (GPX1) OTE2O72Q GPX1_HUMAN Gene/Protein Processing [5]
Glutathione peroxidase 3 (GPX3) OT6PK94R GPX3_HUMAN Gene/Protein Processing [5]
Glutathione reductase, mitochondrial (GSR) OTM2TUYM GSHR_HUMAN Gene/Protein Processing [5]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Gene/Protein Processing [7]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Acetylcholinesterase (AChE) DTT ACHE 6.39E-02 -1.07 -1.15
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 8.8145 11.1543 6.0946 1.6647
TC-71 GDSC2 7.4283 9.2501 6.1457 3.5974
CAL-78 GDSC2 7.5831 17.9101 1.9666 24.8023
SK-PN-DW GDSC2 7.6649 10.339 5.7835 5.2854
EW-18 GDSC2 7.6866 10.8943 5.529 6.7937
ES8 GDSC2 7.8516 10.2604 5.9468 3.9121
SK-ES-1 GDSC2 7.908 9.5257 6.3183 1.7128
MG-63 GDSC2 7.9483 9.8178 6.2108 2.2286
EW-7 GDSC2 7.9928 10.2163 6.0559 3.0176
HuO-3N1 GDSC2 8.0258 17.167 2.6855 20.9336
ES4 GDSC2 8.1603 15.5929 3.568 16.6549
ES6 GDSC2 8.2331 11.1127 5.7898 4.1074
H-EMC-SS GDSC2 8.2856 11.3222 5.7252 4.382
EW-24 GDSC2 8.354 10.538 6.119 2.1134
ES1 GDSC2 8.4203 10.6883 6.0894 2.1735
HOS GDSC2 8.447 10.2148 6.3032 1.1259
EW-22 GDSC2 8.4943 12.6924 5.2158 6.9249
G-292 clone A141B1 GDSC2 8.615 11.3873 5.8897 2.9324
A-673 GDSC2 8.6528 10.3588 6.3402 0.7933
CAL-72 GDSC2 8.6568 12.0653 5.6092 4.3864
SaOS-2 GDSC2 8.6691 10.094 6.4479 0.4237
EW-13 GDSC2 8.815 10.7133 6.2732 0.9155
CADO-ES1 GDSC2 8.8328 10.3006 6.4371 0.3715
HuO9 GDSC2 8.9131 11.1903 6.1275 1.4172
MHH-ES-1 GDSC2 8.9328 11.3867 6.0563 1.709
ES7 GDSC2 8.9382 15.014 4.4053 10.5509
U2OS GDSC2 8.986 11.7795 5.9183 2.2904
EW-3 GDSC2 8.9898 11.4097 6.0745 1.5687
CHSA8926 GDSC2 9.0279 15.183 4.3847 10.4747
EW-1 GDSC2 9.2333 11.1886 6.2696 0.6392
EW-16 GDSC2 9.3274 11.3973 6.23 0.7062
SJSA-1 GDSC2 9.3748 10.7666 6.4733 0.1303
NOS-1 [Human HNSCC] GDSC2 9.4232 11.5908 6.1969 0.7524
NY GDSC2 9.4597 11.6812 6.1779 0.7904
EW-11 GDSC2 9.4986 11.8347 6.1359 0.9033
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC2 7.3669 11.1842 5.1471 9.9379
OACP4 C GDSC2 7.4849 9.5997 6.0158 4.2663
ESO-26 GDSC2 7.7914 10.0166 6.0228 3.5815
ESO-51 GDSC2 8.1797 10.5545 6.0133 2.9402
KYSE-220 GDSC2 8.6526 10.4909 6.2879 0.9956
KYAE-1 GDSC2 8.8571 10.5944 6.3374 0.656
OACM5.1 C GDSC2 8.9808 19.4195 2.2926 20.1655
SK-GT-4 GDSC2 9.2124 12.5339 5.7138 3.0035
FLO-1 GDSC2 9.8199 12.4303 6.0448 0.9943
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 7.7835 10.3888 5.8408 4.6821
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC2 7.4604 11.0101 5.3052 8.7225
SJNB-14 GDSC2 7.4792 10.6498 5.4973 7.4875
SK-N-DZ GDSC2 7.4908 10.0285 5.8111 5.5148
CHP-212 GDSC2 7.4995 9.2698 6.185 3.2049
SJNB-10 GDSC2 7.5152 9.3943 6.136 3.4678
IMR-5 GDSC2 7.7404 11.6877 5.1797 8.7964
TGW GDSC2 7.9888 9.9205 6.1881 2.2882
SK-N-AS GDSC2 8.379 15.1676 3.939 14.2632
SK-N-BE(2)-M17 GDSC2 8.4698 10.615 6.1472 1.8208
GI-ME-N GDSC2 8.717 14.0632 4.7113 9.3395
SJNB-13 GDSC2 8.7439 10.3484 6.3833 0.5784
KP-N-YN GDSC2 8.8738 11.3477 6.0434 1.8331
NH-12 GDSC2 8.9549 10.5999 6.3757 0.4794
NB1 GDSC2 8.9739 14.8148 4.5242 9.8363
SK-N-FI GDSC2 9.0207 10.7008 6.3648 0.4761
SJNB-7 GDSC2 9.092 10.7174 6.3868 0.3833
Kelly GDSC2 9.1475 10.375 6.5265 0.1028
GOTO GDSC2 9.1961 11.1693 6.2615 0.6869
SiMa GDSC2 9.4201 11.0904 6.3779 0.2789
SK-N-SH GDSC2 9.7034 11.3711 6.3831 0.1919
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 7.2774 9.2013 6.0609 4.4745
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC2 6.0326 7.7495 5.6445 11.0805
MRK-nu-1 GDSC2 7.4888 9.2651 6.18 3.2578
MDA-MB-468 GDSC2 7.6325 10.62 5.624 6.3363
MFM-223 GDSC2 7.7469 16.3627 2.868 20.907
HCC1806 GDSC2 7.8509 11.8575 5.1766 8.5524
CAL-85-1 GDSC2 7.8627 10.4658 5.8569 4.4229
CAL-120 GDSC2 7.8632 9.8935 6.1255 2.8504
Evsa-T GDSC2 7.9344 10.1509 6.0503 3.1528
HCC1395 GDSC2 8.0038 10.351 6.0006 3.3131
CAMA-1 GDSC2 8.028 10.2238 6.0737 2.8569
MDA-MB-415 GDSC2 8.0534 9.823 6.2677 1.7678
Hs 578T GDSC2 8.0612 15.1307 3.7217 16.1477
CAL-51 GDSC2 8.0752 11.6115 5.4522 6.3974
MCF-7 GDSC2 8.0759 10.4085 6.018 3.0879
DU4475 GDSC2 8.1012 9.3559 6.4881 0.6806
MDA-MB-361 GDSC2 8.1283 10.9541 5.7981 4.252
MDA-MB-175-VII GDSC2 8.1956 10.1613 6.1974 1.931
MDA-MB-453 GDSC2 8.2099 11.8083 5.4483 6.1416
HCC1419 GDSC2 8.3048 9.6029 6.4817 0.5421
JIMT-1 GDSC2 8.3158 10.8356 5.9658 2.9813
MDA-MB-231 GDSC2 8.3395 10.7025 6.0387 2.5528
EFM-192A GDSC2 8.3538 11.3331 5.762 4.0509
HDQ-P1 GDSC2 8.3551 10.5101 6.1317 2.0474
HCC1937 GDSC2 8.4002 12.0276 5.4683 5.6486
HCC1500 GDSC2 8.4132 11.3462 5.7918 3.7818
T-47D GDSC2 8.5559 16.4547 3.4369 16.3156
BT-474 GDSC2 8.6896 10.4087 6.3369 0.777
UACC-812 GDSC2 8.6921 10.2867 6.3849 0.6067
MDA-MB-157 GDSC2 8.6983 11.2701 5.9861 2.322
COLO 824 GDSC2 8.7579 17.6289 3.0084 17.7771
CAL-148 GDSC2 8.7711 10.2222 6.4414 0.3894
BT-549 GDSC2 8.8144 10.7943 6.2409 1.0409
OCUB-M GDSC2 8.8506 10.8558 6.233 1.0412
BT-20 GDSC2 8.8614 11.2228 6.0892 1.6381
ZR-75-30 GDSC2 8.8806 12.5598 5.517 4.5224
HCC1954 GDSC2 8.9846 10.7964 6.3143 0.6494
HCC70 GDSC2 9.0074 11.1833 6.1741 1.1382
HCC1187 GDSC2 9.0455 18.4834 2.7989 18.007
EFM-19 GDSC2 9.0652 12.476 5.6594 3.4811
HCC1428 GDSC2 9.0662 11.8195 5.9422 2.0826
MDA-MB-436 GDSC2 9.221 11.0544 6.3145 0.5144
HCC38 GDSC2 9.4344 11.2977 6.3095 0.4273
AU565 GDSC2 9.6867 11.5699 6.308 0.3339
HCC1143 GDSC2 9.837 21.4876 1.9 19.7391
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GB-1 GDSC2 7.4528 9.786 5.9022 5.0402
NMC-G1 GDSC2 7.5436 10.782 5.48 7.4356
SF539 GDSC2 7.6601 9.4135 6.2219 2.6656
U-251MG GDSC2 7.6918 12.6995 4.6447 12.0973
A-172 GDSC2 7.7048 10.1297 5.9118 4.4204
T98G GDSC2 7.7187 9.6646 6.1416 3.024
LN-229 GDSC2 7.7886 11.6974 5.21 8.4978
LN-18 GDSC2 7.8895 12.8528 4.7168 11.1831
SK-MG-1 GDSC2 7.9051 10.0518 6.0781 3.0466
D283 Med GDSC2 7.9876 9.7581 6.2599 1.9036
LN-405 GDSC2 8.0128 9.9151 6.2043 2.1625
LNZTA3WT4 GDSC2 8.0338 10.3718 6.0094 3.21
GaMG GDSC2 8.0415 12.3379 5.0783 8.6985
GI-1 GDSC2 8.0479 12.6056 4.9527 9.4261
YH-13 GDSC2 8.0577 9.7876 6.2856 1.67
U-118MG GDSC2 8.2343 10.0031 6.2859 1.4403
Becker GDSC2 8.2731 10.1408 6.2474 1.5786
ONS-76 GDSC2 8.2784 10.3996 6.1383 2.1196
Daoy GDSC2 8.286 10.4604 6.1158 2.2254
CAS-1 GDSC2 8.3214 9.4821 6.5345 0.3601
D-263MG GDSC2 8.377 15.7924 3.6309 15.8145
8-MG-BA GDSC2 8.4745 10.8416 6.052 2.2903
AM-38 GDSC2 8.5469 13.0774 5.0678 7.6711
SW1783 GDSC2 8.5894 16.1081 3.6312 15.3058
KALS-1 GDSC2 8.6402 12.2527 5.5134 4.9501
U-87MG ATCC GDSC2 8.6767 10.0024 6.4845 0.32
H4 GDSC2 8.7248 10.8641 6.1707 1.4204
MOG-G-CCM GDSC2 8.7318 10.8736 6.1701 1.4155
DK-MG GDSC2 8.7427 10.0429 6.4953 0.2663
42-MG-BA GDSC2 8.8359 10.5361 6.3507 0.626
SF268 GDSC2 8.8636 11.6852 5.8948 2.5608
D-392MG GDSC2 8.8702 11.3599 6.0365 1.8692
KS-1 [Human Krukenberg tumour] GDSC2 8.9595 11.702 5.9376 2.2301
MOG-G-UVW GDSC2 9.0398 11.6395 6.0041 1.8287
M059J GDSC2 9.104 10.7283 6.3875 0.3763
DBTRG-05MG GDSC2 9.1318 11.3868 6.1498 1.128
KINGS-1 GDSC2 9.146 11.0736 6.2768 0.6692
SW1088 GDSC2 9.157 10.7578 6.3972 0.3311
PFSK-1 GDSC2 9.3688 11.3646 6.2592 0.5945
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC2 7.7814 9.8115 6.1126 3.0744
TGBC24TKB GDSC2 8.1882 10.6029 5.9963 3.0201
ETK-1 GDSC2 9.225 11.5853 6.1132 1.1914
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC2 8.0973 10.9412 5.7845 4.3895
ESS-1 GDSC2 8.3894 10.4242 6.1869 1.7278
MFE-319 GDSC2 8.5157 16.1922 3.5363 15.939
RL95-2 GDSC2 8.6422 11.7599 5.739 3.6973
EN GDSC2 8.8659 10.3158 6.4444 0.3376
KLE GDSC2 9.41 11.7442 6.1328 0.9757
MFE-296 GDSC2 9.49 11.2823 6.3362 0.3428
AN3-CA GDSC2 10.1538 21.1652 2.2782 17.7158
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 130 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KY821 GDSC2 5.01 7.9786 4.474 22.0754
EM-2 GDSC2 6.4545 9.7279 5.1108 12.8483
MHH-CALL-2 GDSC2 6.7822 8.4111 6.056 5.8738
OCI-AML-2 GDSC2 6.9825 8.0784 6.3913 3.1601
P31/FUJ GDSC2 7.2096 9.5017 5.861 5.8983
HL-60 GDSC2 7.2266 14.0202 3.6213 18.9018
KM-H2 GDSC2 7.2591 9.1008 6.0968 4.2953
TUR GDSC2 7.2879 9.25 6.0447 4.5499
ML-2 GDSC2 7.2987 9.2469 6.0542 4.464
OCI-AML-5 GDSC2 7.3057 9.0872 6.1377 3.9283
NOMO-1 GDSC2 7.3784 9.0165 6.2239 3.2298
SCC-3 GDSC2 7.395 8.7757 6.351 2.4237
SU-DHL-5 GDSC2 7.4136 8.8581 6.3241 2.5473
MOLP-8 GDSC2 7.4216 9.4563 6.0408 4.2567
LAMA-84 GDSC2 7.4505 9.9502 5.8202 5.5539
JJN-3 GDSC2 7.4572 9.2228 6.1788 3.3324
P32/ISH GDSC2 7.4767 9.6951 5.9637 4.6054
P30/OHK GDSC2 7.4834 9.3772 6.1224 3.6183
Karpas-422 GDSC2 7.4877 9.7778 5.9313 4.78
WSU-DLCL2 GDSC2 7.5194 10.4795 5.6109 6.685
AMO1 GDSC2 7.5541 9.7111 6.0102 4.1477
K-562 GDSC2 7.5799 9.3492 6.2006 2.9466
ARH-77 GDSC2 7.6138 9.7889 6.0135 3.9985
OCI-M1 GDSC2 7.6274 9.8044 6.0153 3.9589
P12-Ichikawa GDSC2 7.6486 9.0477 6.3836 1.7638
ST486 GDSC2 7.6717 10.2788 5.8174 5.064
SU-DHL-10 GDSC2 7.679 8.7977 6.5117 1.0357
MM1.S GDSC2 7.6827 10.2671 5.8307 4.959
BL-41 GDSC2 7.6828 9.2294 6.3211 2.0557
KCL-22 GDSC2 7.7058 9.2197 6.3393 1.9148
DEL GDSC2 7.7227 9.1649 6.374 1.6967
Ramos.2G6.4C10 GDSC2 7.726 9.8184 6.0739 3.4078
SUP-T1 GDSC2 7.7528 10.2993 5.863 4.6129
ME1 GDSC2 7.755 17.1773 2.4687 22.503
ALL-PO GDSC2 7.7974 10.6087 5.7448 5.2314
CA46 GDSC2 7.8178 9.9001 6.0942 3.1134
IM-9 GDSC2 7.8208 10.1453 5.9812 3.7694
Karpas-1106P GDSC2 7.8249 9.8339 6.1294 2.8968
LC4-1 GDSC2 7.8403 10.4384 5.8551 4.479
MN-60 GDSC2 7.8866 9.8399 6.1644 2.5886
Namalwa GDSC2 7.8917 11.7106 5.2774 7.85
DB GDSC2 7.8972 9.8934 6.1462 2.6731
MOLT-4 GDSC2 7.9032 10.4902 5.8718 4.2536
Jurkat GDSC2 7.9048 9.4286 6.3592 1.5044
EJM GDSC2 7.9149 11.3482 5.4693 6.6403
JVM-2 GDSC2 7.9285 10.1635 6.0409 3.2179
NCI-H929 GDSC2 7.9306 9.797 6.2099 2.2619
BE-13 GDSC2 7.9564 10.2247 6.0298 3.2313
U-698-M GDSC2 7.978 17.7129 2.3771 22.2731
RC-K8 GDSC2 7.9819 9.5845 6.333 1.5322
CTV-1 GDSC2 7.9894 9.7013 6.286 1.764
L-540 GDSC2 8.0026 9.6676 6.3079 1.6315
SU-DHL-6 GDSC2 8.0047 9.6421 6.3202 1.5657
RPMI-8226 GDSC2 8.0086 10.6128 5.8819 3.99
PF-382 GDSC2 8.0187 10.4036 5.9855 3.373
Karpas-620 GDSC2 8.0642 11.8628 5.324 7.1854
MOLT-13 GDSC2 8.0895 11.7862 5.3782 6.8082
RPMI-8402 GDSC2 8.0956 11.1538 5.6834 4.985
DND-41 GDSC2 8.0967 10.233 6.11 2.5428
U266B1 GDSC2 8.1616 11.7701 5.4344 6.3224
RPMI-8866 GDSC2 8.1813 9.7705 6.357 1.1678
Karpas-45 GDSC2 8.1842 12.2934 5.199 7.6675
KMS-12-BM GDSC2 8.2087 9.7502 6.3789 1.0393
WIL2 NS GDSC2 8.2094 10.0467 6.2544 1.6248
Raji GDSC2 8.2095 9.5361 6.4658 0.6753
KMOE-2 GDSC2 8.2143 10.7948 5.9245 3.3766
SK-MM-2 GDSC2 8.2332 10.333 6.1427 2.1609
Karpas-299 GDSC2 8.2465 11.2936 5.7141 4.5176
HDLM-2 GDSC2 8.2506 10.5271 6.0665 2.5384
NKM-1 GDSC2 8.2569 11.8245 5.4715 5.9105
BC-1 GDSC2 8.2645 10.3191 6.1659 1.9968
MOLM-13 GDSC2 8.29 9.8983 6.3573 1.0497
GDM-1 GDSC2 8.3013 11.2924 5.7487 4.2195
SU-DHL-8 GDSC2 8.3178 9.8987 6.3704 0.9658
CESS GDSC2 8.3398 10.4525 6.1485 1.983
RS4;11 GDSC2 8.3599 11.5144 5.6822 4.4936
ATN-1 GDSC2 8.3763 10.0647 6.3306 1.0782
L-363 GDSC2 8.3821 9.6 6.5152 0.3835
EB2 GDSC2 8.4017 10.2388 6.2712 1.3153
A4/Fukuda GDSC2 8.4264 9.9753 6.3899 0.7881
A3/Kawakami GDSC2 8.4285 9.4139 6.6003 0.1527
KOPN-8 GDSC2 8.4349 10.3142 6.2563 1.3468
Mono-Mac-6 GDSC2 8.4459 14.0205 4.5461 10.8483
KE-37 GDSC2 8.5321 9.6916 6.5408 0.2433
RPMI-6666 GDSC2 8.5372 11.386 5.8463 3.2814
Daudi GDSC2 8.561 10.1936 6.3641 0.7762
JVM-3 GDSC2 8.5855 10.0243 6.4398 0.4963
SUP-M2 GDSC2 8.6081 9.6108 6.5969 0.1117
MHH-PREB-1 GDSC2 8.6227 10.2012 6.3881 0.6433
YT GDSC2 8.633 10.1213 6.4229 0.5206
Ku812 GDSC2 8.6499 10.4293 6.3111 0.9062
NALM-6 GDSC2 8.6551 11.1475 6.016 2.2297
Karpas-231 GDSC2 8.6726 10.1419 6.4315 0.4705
BV-173 GDSC2 8.6754 10.438 6.3192 0.8541
KG-1 GDSC2 8.7079 10.4774 6.3181 0.8321
MOLT-16 GDSC2 8.7291 10.1133 6.4646 0.3475
Reh GDSC2 8.7386 10.2265 6.4268 0.4475
MLMA GDSC2 8.7495 10.7061 6.2464 1.0762
L-1236 GDSC2 8.7563 11.0778 6.0976 1.7159
HH [Human lymphoma] GDSC2 8.7571 11.322 5.9947 2.204
MV4-11 GDSC2 8.8451 10.4193 6.3983 0.4729
OPM-2 GDSC2 8.8759 10.0367 6.5462 0.1289
BALL-1 GDSC2 8.8994 10.4762 6.3991 0.4421
HAL-01 GDSC2 8.9112 10.8505 6.2621 0.8813
HC-1 GDSC2 8.9467 10.6033 6.3711 0.497
DG-75 GDSC2 8.9522 10.563 6.3882 0.4455
GA-10 GDSC2 8.9844 10.3419 6.4798 0.2152
EoL-1 GDSC2 8.9877 11.0846 6.2043 1.0375
Loucy GDSC2 9.0404 10.4718 6.4549 0.2471
Hs 445 GDSC2 9.0578 10.3623 6.4993 0.1602
ALL-SIL GDSC2 9.0828 10.8187 6.3461 0.4965
JURL-MK1 GDSC2 9.0896 10.7209 6.3846 0.3899
CML-T1 GDSC2 9.1094 10.3736 6.5137 0.1268
WSU-NHL GDSC2 9.1106 10.4094 6.5019 0.1438
L-428 GDSC2 9.1215 11.002 6.2936 0.6313
SR GDSC2 9.1257 10.7008 6.4057 0.3237
H9 GDSC2 9.1419 10.5976 6.4482 0.2281
SUP-HD1 GDSC2 9.1773 11.2409 6.2264 0.8148
SUP-B15 GDSC2 9.183 10.6158 6.4568 0.2002
697 GDSC2 9.2052 10.5014 6.5039 0.1215
TK [Human B-cell lymphoma] GDSC2 9.2387 10.6634 6.4604 0.1793
CCRF-CEM GDSC2 9.2901 10.6847 6.4714 0.1502
Granta-519 GDSC2 9.3226 10.6999 6.4776 0.1345
GR-ST GDSC2 9.4495 11.5874 6.209 0.6989
VAL GDSC2 9.4712 11.4571 6.266 0.5231
MEG-01 GDSC2 9.506 11.6523 6.2078 0.6701
JSC-1 GDSC2 9.5213 11.4242 6.2974 0.4203
VL51 GDSC2 9.5329 11.3233 6.3377 0.3241
CTB-1 GDSC2 9.5559 11.4725 6.2933 0.4157
Jiyoye GDSC2 9.6065 11.2184 6.401 0.1864
⏷ Show the Full List of 130 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-195 GDSC2 7.7079 10.5795 5.6972 5.7165
A-498 GDSC2 7.7288 10.3211 5.8363 4.8255
KMRC-1 GDSC2 7.9126 9.3578 6.3941 1.3165
A-704 GDSC2 8.134 10.0322 6.2202 1.8996
BFTC-909 GDSC2 8.2005 10.1576 6.2016 1.9027
LB996-RCC GDSC2 8.348 13.169 4.8898 9.1164
KMRC-20 GDSC2 8.448 13.2334 4.9271 8.6857
SN12C GDSC2 8.6241 11.9269 5.6528 4.1999
ACHN GDSC2 8.7117 13.7128 4.8747 8.4339
769-P GDSC2 8.718 10.7387 6.2186 1.2205
SW13 GDSC2 8.7496 10.5632 6.303 0.8557
VMRC-RCZ GDSC2 8.8197 13.875 4.8688 8.2497
OS-RC-2 GDSC2 8.8316 12.6458 5.4488 4.979
CAL-54 GDSC2 9.0006 11.1307 6.1919 1.0745
RCC10RGB GDSC2 9.0456 11.1873 6.1897 1.0457
786-O GDSC2 9.0848 11.2751 6.1727 1.0788
TK-10 GDSC2 9.5357 11.5227 6.2673 0.4891
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C1 GDSC2 7.2947 9.2711 6.0393 4.5667
NCI-H747 GDSC2 7.323 11.5251 4.9433 11.2973
HT-29 GDSC2 7.8439 10.0032 6.0626 3.248
SNU-61 GDSC2 7.9366 10.254 6.0039 3.4164
SNU-C5 GDSC2 7.9442 10.4694 5.9081 3.9598
SNU-C2B GDSC2 7.9614 11.5506 5.4037 6.9331
SW1417 GDSC2 7.9814 10.1176 6.0943 2.8209
C2BBe1 GDSC2 7.9944 10.6216 5.8687 4.0938
CW-2 GDSC2 8.0417 11.0539 5.6955 5.0207
HCT 15 GDSC2 8.159 11.2985 5.6561 5.0209
CCK-81 GDSC2 8.1641 10.4011 6.0734 2.6356
KM12 GDSC2 8.2092 12.5716 5.0822 8.301
SW1116 GDSC2 8.2319 10.0167 6.2789 1.4765
SW837 GDSC2 8.2363 10.3591 6.133 2.2074
HCC2998 GDSC2 8.349 10.2401 6.2443 1.501
LS513 GDSC2 8.365 10.3512 6.2054 1.6683
SK-CO-1 GDSC2 8.461 9.9906 6.3993 0.7237
LS411N GDSC2 8.4657 10.1365 6.3436 0.938
SW1463 GDSC2 8.5042 10.6359 6.1561 1.7354
SNU-175 GDSC2 8.527 11.5364 5.7727 3.6987
COLO 678 GDSC2 8.5297 12.6619 5.2532 6.6394
CL-11 GDSC2 8.5656 11.9208 5.6206 4.4789
CaR-1 GDSC2 8.5848 11.357 5.8862 2.9954
HT-55 GDSC2 8.5908 10.1075 6.4104 0.5889
LS1034 GDSC2 8.6158 10.1432 6.4074 0.5823
T84 GDSC2 8.6196 10.8749 6.1139 1.7977
SNU-407 GDSC2 8.6319 10.8294 6.1393 1.664
HCT 116 GDSC2 8.6443 12.2427 5.5205 4.9031
LS180 GDSC2 8.6673 10.5587 6.2675 1.0649
MDST8 GDSC2 8.7024 10.624 6.2575 1.0734
SW948 GDSC2 8.7406 10.1763 6.4461 0.3917
SW626 GDSC2 8.768 14.1229 4.7169 9.2021
COLO205 GDSC2 8.9276 10.1955 6.51 0.1756
GP5d GDSC2 8.9498 11.3177 6.093 1.529
SW620 GDSC2 9.0884 10.5963 6.4288 0.2858
LS123 GDSC2 9.1305 10.8853 6.3406 0.4874
DiFi GDSC2 9.1619 11.5462 6.1001 1.2977
RCM-1 [Human ESC] GDSC2 9.1696 10.7459 6.4062 0.3059
LoVo GDSC2 9.1982 11.2893 6.2167 0.8334
RKO GDSC2 9.215 10.896 6.3698 0.3726
COLO 320HSR GDSC2 9.3077 10.9723 6.3777 0.318
SW48 GDSC2 9.3695 11.1793 6.3272 0.4114
NCI-H716 GDSC2 9.6454 11.4823 6.3235 0.3156
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 9.0624 10.946 6.2902 0.6785
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC2 6.7099 11.9055 4.2494 17.139
JHH-6 GDSC2 7.3016 8.6744 6.336 2.7151
Huh-7 GDSC2 7.3195 13.4323 3.9897 16.749
SNU-423 GDSC2 7.886 10.0055 6.0878 3.0255
HuH-1 GDSC2 8.2518 9.7599 6.3956 0.9232
JHH-4 GDSC2 8.2692 11.6399 5.5665 5.3309
HLE GDSC2 8.4089 10.6035 6.1201 2.0337
SNU-387 GDSC2 8.6305 10.6278 6.2222 1.2918
SNU-398 GDSC2 8.7178 15.6429 3.9499 13.4197
JHH-7 GDSC2 8.8147 10.6257 6.3072 0.7902
SK-HEP-1 GDSC2 9.3207 15.2264 4.5555 8.982
Hep-G2/C3A GDSC2 9.3458 10.4096 6.5817 0.0322
JHH-2 GDSC2 9.7899 18.3957 3.3608 13.9651
SNU-449 GDSC2 10.2984 18.8217 3.4931 12.3788
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 126 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1623 GDSC2 7.049 9.2469 5.8614 6.3257
DMS 273 GDSC2 7.1753 13.0253 4.0766 16.6955
HCC15 GDSC2 7.4065 10.3449 5.5933 7.0718
NCI-H2023 GDSC2 7.4882 9.5127 6.0603 3.9866
NCI-H2228 GDSC2 7.5432 9.945 5.8892 4.9118
NCI-H64 GDSC2 7.5566 9.3906 6.1656 3.2029
Ms-1 GDSC2 7.6491 10.2044 5.8376 4.9903
SBC-3 GDSC2 7.6587 12.2829 4.8257 11.1211
NCI-H1092 GDSC2 7.6709 9.8926 6.0024 3.9455
LC-1/sq GDSC2 7.6906 12.222 4.8797 10.7201
NCI-H1155 GDSC2 7.7009 9.4316 6.239 2.4916
NCI-H1694 GDSC2 7.731 9.5287 6.2127 2.5882
Calu-6 GDSC2 7.7558 10.75 5.648 5.9095
HCC78 GDSC2 7.7791 10.1369 5.9579 3.99
NCI-H226 GDSC2 7.7848 9.8031 6.1187 3.0326
DMS 53 GDSC2 7.7957 10.3296 5.8772 4.4382
NCI-H1648 GDSC2 7.8104 10.8967 5.615 5.9892
NCI-H1341 GDSC2 7.8213 9.7052 6.1866 2.5759
NCI-H847 GDSC2 7.8434 9.5515 6.2699 2.0731
NCI-H2122 GDSC2 7.8986 13.9483 4.1835 14.1568
NCI-H1963 GDSC2 7.9164 11.3163 5.4857 6.5382
LOU-NH91 GDSC2 7.9231 10.3672 5.9425 3.7987
NCI-H727 GDSC2 7.9452 11.3498 5.4894 6.453
NCI-H520 GDSC2 7.9594 9.901 6.1798 2.3811
COR-L105 GDSC2 7.9709 10.3709 5.971 3.5434
NCI-H2141 GDSC2 7.9829 10.2151 6.0505 3.0658
EBC-1 GDSC2 7.9926 10.6759 5.8421 4.2535
NCI-H322M GDSC2 8.0076 11.2168 5.5955 5.6844
NCI-H2087 GDSC2 8.0085 10.5008 5.934 3.6876
HOP-62 GDSC2 8.0229 10.0593 6.1454 2.4675
NCI-H526 GDSC2 8.0427 9.9651 6.199 2.1451
RERF-LC-KJ GDSC2 8.0634 10.9893 5.7402 4.7144
Calu-3 GDSC2 8.0685 10.627 5.9129 3.6995
HOP-92 GDSC2 8.0922 11.7625 5.3913 6.724
COR-L311 GDSC2 8.1086 12.8927 4.8561 9.851
NCI-H1792 GDSC2 8.1202 10.202 6.1374 2.3576
SW1271 GDSC2 8.143 10.5398 5.9983 3.0845
NCI-H1944 GDSC2 8.1657 11.0482 5.7777 4.3004
NCI-H1915 GDSC2 8.2033 11.1544 5.7518 4.3799
NCI-H810 GDSC2 8.205 10.7701 5.9302 3.3606
NCI-H1693 GDSC2 8.2123 11.6195 5.5393 5.6012
NCI-H1581 GDSC2 8.2156 9.8441 6.3433 1.1922
NCI-H2373 GDSC2 8.2172 11.8137 5.4505 6.1134
NCI-H1048 GDSC2 8.2327 15.0193 3.9046 14.7939
COR-L95 GDSC2 8.2406 10.316 6.1543 2.0903
SBC-5 GDSC2 8.2459 15.9491 3.4564 16.9767
NCI-H1688 GDSC2 8.248 10.2831 6.1727 1.9852
NCI-H524 GDSC2 8.2617 10.2559 6.1919 1.8684
NCI-H2347 GDSC2 8.2725 10.5105 6.0862 2.4008
NCI-H1876 GDSC2 8.2866 10.4386 6.1257 2.1731
NCI-H1781 GDSC2 8.313 9.9559 6.3448 1.081
RERF-LC-Sq1 GDSC2 8.32 13.3696 4.7734 9.8474
Lu-139 GDSC2 8.3261 10.0907 6.2954 1.2886
NCI-H2731 GDSC2 8.3304 11.1489 5.8323 3.6954
IA-LM GDSC2 8.3477 10.6553 6.0642 2.4063
Lu-135 GDSC2 8.349 11.6221 5.6254 4.8386
NCI-H1435 GDSC2 8.3518 10.4322 6.1637 1.8905
NCI-H1755 GDSC2 8.3548 10.0831 6.3127 1.1791
PC-14 GDSC2 8.3552 10.2607 6.2387 1.52
NCI-H1563 GDSC2 8.3648 15.7059 3.6644 15.6795
NCI-H2722 GDSC2 8.3701 10.8014 6.0121 2.6484
SK-MES-1 GDSC2 8.3927 12.1286 5.416 5.9662
NCI-H2818 GDSC2 8.3977 12.6388 5.1776 7.3422
NCI-H441 GDSC2 8.3995 10.4095 6.1983 1.6598
EPLC-272H GDSC2 8.4089 10.6912 6.082 2.2271
NCI-H3122 GDSC2 8.4139 10.5578 6.1425 1.9151
COR-L279 GDSC2 8.4191 10.6344 6.1122 2.0598
KNS-62 GDSC2 8.4352 9.9296 6.4118 0.6973
LK-2 GDSC2 8.4429 10.3786 6.2334 1.4431
NCI-H209 GDSC2 8.4482 10.2798 6.277 1.2391
NCI-H2461 GDSC2 8.4561 12.2137 5.4167 5.8396
COLO 668 GDSC2 8.4717 11.3587 5.8206 3.5253
COR-L88 GDSC2 8.4755 10.3505 6.2611 1.2811
NCI-H2591 GDSC2 8.4778 13.4157 4.8599 9.007
NCI-H1651 GDSC2 8.4932 11.4495 5.7922 3.6467
UMC-11 GDSC2 8.5015 10.1491 6.355 0.8605
CPC-N GDSC2 8.5071 10.3649 6.2706 1.2066
NCI-H1703 GDSC2 8.5159 10.539 6.2028 1.5019
NCI-H2369 GDSC2 8.519 9.9253 6.4495 0.5067
Lu-165 GDSC2 8.525 9.9814 6.4307 0.5649
LCLC-103H GDSC2 8.5312 9.7199 6.5303 0.2689
NCI-H2170 GDSC2 8.5332 12.7475 5.215 6.8521
NCI-H196 GDSC2 8.5362 10.3064 6.308 1.0192
NCI-H2009 GDSC2 8.5436 10.4956 6.2344 1.3278
EMC-BAC-2 GDSC2 8.5483 10.8334 6.0948 1.9782
SW1573 GDSC2 8.5525 12.3286 5.424 5.6159
NCI-H2405 GDSC2 8.5669 11.8752 5.6422 4.3556
NCI-H2795 GDSC2 8.5769 12.7402 5.2468 6.5841
NCI-H69 GDSC2 8.6147 10.316 6.34 0.8243
LXF 289 GDSC2 8.6238 10.7923 6.1507 1.6201
NCI-H1299 GDSC2 8.6258 11.3664 5.9049 2.8367
NCI-H1573 GDSC2 8.661 10.4085 6.3243 0.8462
NCI-H1975 GDSC2 8.662 10.7635 6.1816 1.4377
NCI-H2595 GDSC2 8.6686 13.634 4.8837 8.4715
NCI-H358 GDSC2 8.6729 11.0281 6.0763 1.9133
COR-L23 GDSC2 8.7143 10.4948 6.3141 0.8419
NCI-H513 GDSC2 8.7191 11.0386 6.0954 1.7685
NCI-H522 GDSC2 8.7367 12.3744 5.5159 4.7688
NCI-H1838 GDSC2 8.742 12.5083 5.4578 5.0836
NCI-H2342 GDSC2 8.7802 11.178 6.0676 1.8276
NCI-H1355 GDSC2 8.7842 10.7249 6.2548 1.0125
NCI-H82 GDSC2 8.8281 10.22 6.4644 0.3047
Lu-99A GDSC2 8.8353 11.238 6.07 1.7541
PaCa-3 GDSC2 8.8573 14.3765 4.6555 9.3579
NCI-H1993 GDSC2 8.8783 10.9443 6.2104 1.1066
NCI-H1793 GDSC2 8.8786 12.7367 5.4354 4.9728
LCLC-97TM1 GDSC2 8.8882 11.7741 5.8694 2.6549
VMRC-LCD GDSC2 8.9472 11.328 6.0875 1.5556
NCI-H596 GDSC2 8.9756 10.6335 6.3715 0.4804
SHP-77 GDSC2 8.9837 16.9038 3.525 14.9131
Lu-65 GDSC2 8.9966 10.8854 6.2855 0.737
NCI-H2066 GDSC2 9.0364 11.1285 6.2087 0.9814
NCI-H650 GDSC2 9.0785 10.6154 6.4182 0.3131
NCI-H1666 GDSC2 9.0949 12.7307 5.5635 3.9381
HCC827 GDSC2 9.1639 10.8123 6.3802 0.3685
NCI-H661 GDSC2 9.1913 11.5476 6.113 1.221
NCI-H2085 GDSC2 9.2051 11.0045 6.3265 0.4892
DMS 114 GDSC2 9.2425 10.8949 6.3807 0.3358
SK-LU-1 GDSC2 9.2539 17.8668 3.2477 15.5991
NCI-H23 GDSC2 9.2966 11.1129 6.3229 0.4546
A-549 GDSC2 9.3039 11.1236 6.3219 0.454
NCI-H446 GDSC2 9.4931 10.9927 6.438 0.1559
NCI-H1650 GDSC2 9.5052 12.6651 5.8076 2.2087
NCI-H1568 GDSC2 9.5212 11.3656 6.3184 0.371
EKVX GDSC2 9.5264 13.2169 5.5856 3.2275
HARA [Human squamous cell lung carcinoma] GDSC2 9.5751 11.4912 6.2939 0.4066
⏷ Show the Full List of 126 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 8.9324 10.9506 6.2323 0.976
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-6 GDSC2 7.8325 10.1655 5.9792 3.7582
KYSE-410 GDSC2 7.8944 9.9351 6.1254 2.7958
COLO 680N GDSC2 7.9834 9.6035 6.3255 1.5683
EC-GI-10 GDSC2 8.2524 22.5856 0.1672 28.3609
TE-5 GDSC2 8.3369 10.4478 6.149 1.984
TE-4 GDSC2 8.3516 10.6489 6.0691 2.3748
KYSE-140 GDSC2 8.3557 11.389 5.7375 4.1866
T.T GDSC2 8.3661 10.9248 5.9547 2.9625
KYSE-450 GDSC2 8.4088 11.7535 5.6016 4.8651
TE-10 GDSC2 8.5604 14.2671 4.5065 10.8127
TE-1 GDSC2 8.5956 14.912 4.2188 12.2943
OE19 GDSC2 8.6624 10.037 6.4662 0.3753
OE21 GDSC2 8.9538 11.2975 6.1032 1.4811
TE-9 GDSC2 8.9771 10.3043 6.4903 0.1975
KYSE-270 GDSC2 9.0602 11.1708 6.2027 0.9853
KYSE-70 GDSC2 9.0656 10.7606 6.3606 0.4647
KYSE-150 GDSC2 9.066 10.4089 6.4862 0.1801
KYSE-180 GDSC2 9.0822 11.1197 6.2322 0.8614
TE-15 GDSC2 9.2487 11.5641 6.1322 1.0998
OE33 GDSC2 9.2501 11.1921 6.2752 0.6128
TE-8 GDSC2 9.407 11.3598 6.2762 0.5267
KYSE-520 GDSC2 10.0146 11.9488 6.2957 0.2585
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVISE GDSC2 7.3423 8.7687 6.3186 2.7318
RMG-I GDSC2 7.5422 11.7401 5.006 10.3409
TOV-21G GDSC2 7.5478 9.8762 5.9259 4.6761
EFO-21 GDSC2 7.7826 10.1053 5.9752 3.8802
OVCAR-4 GDSC2 8.1167 10.4196 6.0373 2.9111
OC 314 GDSC2 8.1412 9.9383 6.265 1.6616
TYK-nu GDSC2 8.158 10.2333 6.1449 2.2602
TOV-112D GDSC2 8.1715 10.5303 6.0194 2.9197
OV56 GDSC2 8.1827 9.5651 6.4419 0.7948
DOV13 GDSC2 8.2578 10.2584 6.1887 1.8899
OVCAR-3 GDSC2 8.3081 13.2905 4.8034 9.7019
ES-2 GDSC2 8.3234 9.9424 6.3553 1.0247
IGROV-1 GDSC2 8.4658 10.8023 6.0644 2.2387
OV-90 GDSC2 8.5472 11.2973 5.8915 3.0235
OVKATE GDSC2 8.5828 10.3905 6.2959 1.0261
Kuramochi GDSC2 8.6988 11.1707 6.029 2.1099
A2780 GDSC2 8.7194 11.0832 6.0767 1.8556
OAW42 GDSC2 8.7706 10.4756 6.3461 0.6852
SK-OV-3 GDSC2 8.9709 10.6461 6.365 0.5017
Caov-3 GDSC2 8.9886 10.6405 6.3742 0.4661
OVCAR-5 GDSC2 8.9947 10.8949 6.2811 0.7534
Caov-4 GDSC2 9.0447 11.6703 5.9938 1.8699
OVTOKO GDSC2 9.1331 11.3011 6.184 0.9976
OAW28 GDSC2 9.1878 11.5914 6.0939 1.2994
OVCAR-8 GDSC2 10.0829 20.6645 2.4708 17.12
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Panc 04.03 GDSC2 7.6752 9.8208 6.0395 3.7143
KP-2 GDSC2 7.7456 9.2348 6.3558 1.7596
PaTu 8988t GDSC2 7.7457 9.7688 6.1099 3.1574
Panc 10.05 GDSC2 7.7483 10.0157 5.9952 3.8306
KP-4 GDSC2 7.8456 9.689 6.2087 2.4094
PaTu 8902 GDSC2 7.9652 9.6742 6.2845 1.807
YAPC GDSC2 8.0006 9.4297 6.4091 1.1328
Hs 766T GDSC2 8.1651 14.2892 4.2136 13.3312
CFPAC-1 GDSC2 8.1968 10.6581 5.9764 3.1165
Panc 03.27 GDSC2 8.2089 10.5903 6.0142 2.8879
PL4 GDSC2 8.2628 10.0998 6.2595 1.5324
SW1990 GDSC2 8.3136 11.7039 5.5648 5.2553
Panc 02.03 GDSC2 8.3494 10.8162 5.9937 2.7777
SU.86.86 GDSC2 8.3762 10.1671 6.2884 1.2653
Capan-1 GDSC2 8.4979 13.9031 4.639 10.2133
DAN-G GDSC2 8.544 10.3805 6.2817 1.1219
SUIT-2 GDSC2 8.6347 11.8645 5.6874 3.9915
MIA PaCa-2 GDSC2 8.7334 10.1676 6.4465 0.3944
Panc 08.13 GDSC2 8.742 11.2925 5.9994 2.2001
Capan-2 GDSC2 8.7452 11.9002 5.7352 3.5567
HuP-T4 GDSC2 8.7601 11.1307 6.0773 1.8055
BxPC-3 GDSC2 9.0023 11.1377 6.1899 1.0809
HPAC GDSC2 9.035 10.7405 6.3559 0.4938
AsPC-1 GDSC2 9.1826 11.0282 6.3088 0.5508
KP-3 GDSC2 9.2196 11.7986 6.0254 1.5515
HuP-T3 GDSC2 9.3348 11.1614 6.3202 0.4442
KP-1N GDSC2 9.4359 11.4552 6.2526 0.5776
PSN1 GDSC2 9.5239 11.1224 6.4045 0.2006
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC2 8.4503 11.3087 5.8308 3.5045
MPP 89 GDSC2 8.7183 10.2992 6.3912 0.5691
NCI-H28 GDSC2 8.7527 12.3237 5.5486 4.5604
NCI-H2052 GDSC2 8.834 10.605 6.3236 0.7185
IST-Mes1 GDSC2 9.1107 11.6553 6.032 1.6306
NCI-H2452 GDSC2 9.3639 11.4376 6.23 0.6845
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC2 8.1716 12.0117 5.3256 6.9456
VCaP GDSC2 8.1791 12.7697 4.9655 9.0517
LNCaP clone FGC GDSC2 8.5841 18.6677 2.368 20.8047
DU145 GDSC2 9.3185 14.4598 4.9111 7.0772
22Rv1 GDSC2 9.4126 12.0851 5.9999 1.4774
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 8.3561 10.3005 6.2223 1.5976
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-1 GDSC2 7.3421 8.9595 6.2261 3.2977
WM793 GDSC2 7.4743 9.5575 6.0289 4.2103
UACC-257 GDSC2 7.6019 10.3997 5.7096 5.8814
G-361 GDSC2 7.6525 10.7652 5.5675 6.6367
A2058 GDSC2 7.8089 10.8279 5.6472 5.7975
GAK GDSC2 7.8956 11.5948 5.3364 7.4855
WM115 GDSC2 7.922 9.3579 6.399 1.2797
A101D GDSC2 8.0239 10.0663 6.1428 2.4798
IGR-37 GDSC2 8.0452 9.6366 6.3441 1.3924
CHL-1 GDSC2 8.0934 11.0634 5.7246 4.7469
LOX-IMVI GDSC2 8.1514 10.2143 6.1496 2.2449
WM35 GDSC2 8.1575 10.35 6.0926 2.5418
RVH-421 GDSC2 8.1831 12.2859 5.2018 7.6531
WT2-iPS GDSC2 8.1835 9.5084 6.465 0.7008
UACC-62 GDSC2 8.2061 14.6074 4.0875 13.9053
COLO 679 GDSC2 8.2204 9.939 6.306 1.3612
COLO 792 GDSC2 8.3648 10.6376 6.0814 2.2921
A-375 GDSC2 8.3739 10.6005 6.1025 2.1704
SK-MEL-24 GDSC2 8.4369 12.7711 5.1407 7.4759
MeWo GDSC2 8.6654 10.7881 6.1731 1.4723
RPMI-7951 GDSC2 8.7569 10.0558 6.4961 0.259
SH-4 GDSC2 8.7659 17.2717 3.1894 16.9594
HT-144 GDSC2 8.8643 13.4154 5.1133 6.7927
COLO 829 GDSC2 9.0003 15.3208 4.3004 10.9794
WM1552C GDSC2 9.0027 11.3776 6.0938 1.4728
IGR-1 GDSC2 9.0284 18.7299 2.6658 18.5934
IST-MEL1 GDSC2 9.1988 11.1983 6.2517 0.7165
WM278 GDSC2 9.2734 11.1153 6.3129 0.4924
HMV-II GDSC2 9.3101 12.3934 5.824 2.3519
Mel JuSo GDSC2 9.9604 17.57 3.8646 11.2735
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1080 GDSC2 7.7876 10.4629 5.8081 4.8703
SK-UT-1 GDSC2 7.9049 9.8326 6.1786 2.4776
SW982 GDSC2 7.9801 9.4954 6.3705 1.3457
MES-SA GDSC2 7.9878 10.8104 5.7756 4.6545
MFH-ino GDSC2 8.1426 10.4147 6.0548 2.772
SW684 GDSC2 8.1823 10.0599 6.2343 1.7611
Rh30 GDSC2 8.2464 10.3677 6.1348 2.1836
EW-8 GDSC2 8.4244 10.1955 6.3002 1.1619
VA-ES-BJ GDSC2 8.5003 11.4801 5.7825 3.6888
GCT GDSC2 8.5004 10.4386 6.2369 1.3631
KYM-1 GDSC2 8.6919 10.0987 6.4553 0.3908
SW872 GDSC2 8.7148 10.6344 6.2591 1.0558
SK-LMS-1 GDSC2 8.7437 11.1217 6.0728 1.8454
G-402 GDSC2 8.7665 12.3783 5.532 4.6292
RD GDSC2 8.7773 13.6583 4.9436 7.9144
RKN GDSC2 8.7845 9.9569 6.541 0.1599
Hs 633.T GDSC2 8.7846 10.2028 6.4538 0.3501
A-204 GDSC2 9.1045 12.4076 5.7107 3.1631
Rh41 GDSC2 9.2553 10.9146 6.3785 0.3359
G-401 GDSC2 9.4975 11.6834 6.1927 0.7208
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-5 GDSC2 6.8078 8.1505 6.2083 4.8327
Fu97 GDSC2 7.3603 16.2561 2.6128 23.0119
SNU-1 GDSC2 7.7298 9.4202 6.262 2.3084
RERF-GC-1B GDSC2 7.8827 10.9673 5.6306 5.7374
MKN45 GDSC2 7.926 12.4515 4.9404 9.7847
AGS GDSC2 8.1327 11.3017 5.6377 5.1807
IM95 GDSC2 8.1591 10.7611 5.9066 3.5733
NUGC-4 GDSC2 8.2951 10.4889 6.1083 2.2515
NUGC-3 GDSC2 8.3338 12.5176 5.1928 7.3863
MKN28 GDSC2 8.3576 11.6625 5.612 4.8999
ECC10 GDSC2 8.4344 10.1796 6.3115 1.1028
Hs 746.T GDSC2 8.5369 10.2056 6.3486 0.8555
OCUM-1 GDSC2 8.5967 10.8019 6.133 1.7344
HSC-39 GDSC2 8.6794 10.3961 6.3373 0.7831
23132/87 GDSC2 8.7159 9.9823 6.5067 0.2504
KATO III GDSC2 8.7282 10.7811 6.2062 1.263
SNU-16 GDSC2 8.7456 9.9742 6.5207 0.2099
TGBC11TKB GDSC2 8.7679 10.4151 6.3681 0.6129
NCI-N87 GDSC2 8.8811 11.1307 6.1365 1.4101
SK-GT-2 GDSC2 8.9458 11.6278 5.962 2.1303
HGC-27 GDSC2 8.9506 15.7089 4.0802 12.2361
RF-48 GDSC2 8.9953 10.7284 6.3443 0.5495
GCIY GDSC2 9.0863 11.2741 6.1738 1.0734
SNG-M GDSC2 9.0325 10.6403 6.3916 0.3978
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC2 7.4297 9.1283 6.2055 3.2297
K5 GDSC2 7.8204 9.7194 6.1795 2.618
B-CPAP GDSC2 7.9664 11.4138 5.4732 6.5045
FTC-133 GDSC2 8.0108 12.6537 4.9027 9.8066
CGTH-W-1 GDSC2 8.3125 12.591 5.1433 7.7201
ASH-3 GDSC2 8.3807 9.9494 6.3793 0.8698
CAL-62 GDSC2 8.4906 10.0111 6.4044 0.682
WRO GDSC2 8.4992 12.7908 5.1724 7.1657
HTC-C3 GDSC2 8.5727 11.1679 5.9629 2.6115
8505C GDSC2 8.7073 11.5255 5.8799 2.8498
TT2609-C02 GDSC2 8.8241 13.1688 5.203 6.3647
8305C GDSC2 8.8408 10.5123 6.3617 0.5872
BHT-101 GDSC2 8.8653 10.4395 6.399 0.46
TT GDSC2 9.205 10.9556 6.3443 0.4411
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-4 GDSC2 7.4525 9.7167 5.9359 4.8325
HSC-2 GDSC2 7.6236 9.8555 5.9882 4.1305
HO-1-u-1 GDSC2 7.7442 10.5199 5.7511 5.3079
FaDu GDSC2 7.8951 9.7079 6.2294 2.2121
SCC-9 GDSC2 8.1421 11.6663 5.4709 6.1468
OSC-20 GDSC2 8.1627 12.9481 4.8674 9.6609
NCI-H3118 GDSC2 8.1685 10.3871 6.0822 2.5806
SKN-3 GDSC2 8.1792 10.7279 5.934 3.3835
Ca9-22 GDSC2 8.2133 12.0273 5.3462 6.7363
PCI-30 GDSC2 8.3074 11.618 5.6011 5.0567
SCC-15 GDSC2 8.3337 11.0341 5.8866 3.388
BICR 22 GDSC2 8.3342 9.5982 6.4961 0.4731
LB771-HNC GDSC2 8.5123 10.7322 6.1192 1.9038
Detroit 562 GDSC2 8.5299 12.7072 5.232 6.7611
UPCI-SCC-090 GDSC2 8.6088 11.1373 5.9958 2.3927
HSC-4 GDSC2 8.6167 13.9208 4.7119 9.5477
HSC-3 GDSC2 8.6299 10.2557 6.3702 0.7011
CAL-33 GDSC2 8.6612 10.867 6.1382 1.6357
BICR 78 GDSC2 8.7018 11.0546 6.0798 1.8618
HO-1-N-1 GDSC2 8.8463 10.7681 6.2656 0.9192
CAL-27 GDSC2 9.1012 16.3924 3.8544 13.055
SAT [Human HNSCC] GDSC2 9.1079 11.6512 6.0324 1.632
SAS GDSC2 9.1278 10.9632 6.3107 0.5754
JHU-022 GDSC2 9.3581 12.1852 5.9338 1.806
DOK GDSC2 9.472 12.6343 5.8041 2.261
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
639V GDSC2 7.5751 9.433 6.1576 3.2126
TCCSUP GDSC2 7.8064 10.1664 5.9618 3.9124
BFTC-905 GDSC2 7.9336 9.5386 6.3267 1.6316
5637 GDSC2 8.002 10.2275 6.0564 2.9987
SW780 GDSC2 8.0138 10.3162 6.0228 3.1688
HT-1197 GDSC2 8.0703 10.3344 6.0485 2.9262
647V GDSC2 8.1249 11.0382 5.7566 4.4996
CAL-29 GDSC2 8.1956 10.9084 5.861 3.7677
RT-4 GDSC2 8.1978 13.0958 4.8204 9.8529
RT-112 GDSC2 8.3527 13.2866 4.8363 9.4139
KU-19-19 GDSC2 8.5712 10.0096 6.4394 0.5063
SW1710 GDSC2 8.9583 10.6679 6.3518 0.5481
J82 GDSC2 8.9631 11.89 5.8592 2.6078
UM-UC-3 GDSC2 9.0705 16.316 3.8701 13.0431
HT-1376 GDSC2 9.1567 11.2579 6.211 0.8825
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-1 GDSC2 7.0217 9.333 5.7964 6.813
OVCA420 GDSC2 7.0617 13.2543 3.8694 18.1239
HeLa GDSC2 7.0808 9.1775 5.9216 5.8588
PA-1 GDSC2 7.5681 11.1491 5.3174 8.377
SiSo GDSC2 7.5872 9.8975 5.9431 4.484
DSH1 GDSC2 7.6282 16.1789 2.8659 21.2351
HT-3 GDSC2 7.9075 12.7503 4.7804 10.7691
C-4-I GDSC2 8.0864 10.2304 6.1052 2.5856
SiHa GDSC2 8.1339 15.0625 3.81 15.5209
MS751 GDSC2 8.1386 10.1888 6.1537 2.2424
HEY GDSC2 8.2406 12.6178 5.0815 8.2362
LB831-BLC GDSC2 8.3608 11.7449 5.5755 5.1039
PWR-1E GDSC2 8.4175 10.4421 6.1937 1.66
NT2-D1 GDSC2 8.4417 10.8662 6.0233 2.4846
KGN GDSC2 8.5546 13.6046 4.8213 9.0625
OVMIU GDSC2 8.575 17.0677 3.1498 17.5866
BPH-1 GDSC2 8.5886 12.7182 5.2646 6.4592
PEO1 GDSC2 8.6221 11.4515 5.8652 3.0508
NEC8 GDSC2 8.6696 10.3176 6.3635 0.696
CAL-39 GDSC2 8.7908 11.0918 6.1088 1.626
NCC-IT GDSC2 8.823 10.6983 6.2826 0.874
SW756 GDSC2 8.8719 10.4453 6.3995 0.4552
SKG-IIIa GDSC2 8.8817 11.4471 6.0057 1.9999
SKN GDSC2 9.1551 11.1618 6.2472 0.7596
ME-180 GDSC2 9.1557 11.7963 5.9959 1.7424
Ca Ski GDSC2 9.2528 12.5978 5.7076 2.9815
C-33 A GDSC2 9.3938 11.3715 6.2666 0.5599
DoTc2 4510 GDSC2 9.3953 11.2779 6.3015 0.4649
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug

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