Details of Disease

General Information of Disease (ID: DIS3K8ZM)

Disease Name	Proctitis
Synonyms	rectitis; anus inflammation; inflammation of anus
Disease Class	DB33: Noninfectious colitis/proctitis
Definition	An inflammatory process affecting the anus. It is usually caused by sexually transmitted infectious agents and/or inflammatory bowel disease.
Disease Hierarchy	DIS184KT: Skin inflammation DISZ1FMV: Anal fissure DISWD40R: Disease DISGN23E: Inflammatory bowel disease DIS3K8ZM: Proctitis
ICD Code	ICD-11 ICD-11: DB33.Z
Disease Identifiers	MONDO ID MONDO_0005538 MESH ID D011349 UMLS CUI C0033246 MedGen ID 46113 SNOMED CT ID 3951002

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 5 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Cortisone Acetate	DMG8K57	Approved	Small molecular drug	[1]
Hydrocortisone	DMGEMB7	Approved	Small molecular drug	[2]
Mesalazine	DMOL5IU	Approved	Small molecular drug	[3]
Phenylephrine	DMZHUO5	Approved	Small molecular drug	[4]
Pramoxine	DMZ2LGD	Approved	Small molecular drug	[5]
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This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
AP-004	DM1H351	Investigative	NA	[6]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Cortisone acetate FDA Label
2	Hydrocortisone FDA Label
3	Optimized Management of Ulcerative Proctitis: When and How to Use Mesalazine Suppository. Digestion. 2018;97(1):59-63.
4	Isoproterenol FDA Label
5	Pramoxine FDA Label
6	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.