Details of Disease | DrugMAP

General Information of Disease (ID: DIS5IK09)

Disease Name	Glucose metabolism disease
Synonyms	glucose metabolism disorder; disorder of glucose metabolism
Definition	A metabolic disorder characterized by abnormal blood glucose levels.
Disease Hierarchy	DIS71G5H: Metabolic disorder DIS5IK09: Glucose metabolism disease
Disease Identifiers	MONDO ID MONDO_0002908 MESH ID D044882 UMLS CUI C1257958 MedGen ID 226229 SNOMED CT ID 126877002

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 3 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
G6PC	TTBQMJ8	Strong	Biomarker	[1]
GCK	TTDLNGZ	Strong	Altered Expression	[2]
NR3C1	TTOZRK6	Strong	Biomarker	[3]
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This Disease Is Related to 1 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
SLC2A2	DTUJPOL	Strong	Biomarker	[4]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ACSL1	OTB06ESI	Strong	Biomarker	[5]
TAS1R3	OTOVM44D	Strong	Biomarker	[6]
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References

1	Lupinus albus Conglutin Gamma Modifies the Gene Expressions of Enzymes Involved in Glucose Hepatic Production In Vivo.Plant Foods Hum Nutr. 2017 Jun;72(2):134-140. doi: 10.1007/s11130-016-0597-7.
2	The adverse effects of perinatal exposure to nonylphenol on carbohydrate metabolism in male offspring rats.Int J Environ Health Res. 2017 Oct;27(5):368-376. doi: 10.1080/09603123.2017.1373275. Epub 2017 Sep 11.
3	Association Between NR3C1 Gene Polymorphisms and Toxicity Induced by Glucocorticoids Therapy in Saudi Children with Acute Lymphoblastic Leukemia.Asian Pac J Cancer Prev. 2018 May 26;19(5):1415-1423. doi: 10.22034/APJCP.2018.19.5.1415.
4	Effects of polysaccharide from the fruiting bodies of Auricularia auricular on glucose metabolism in (60)Co--radiated mice.Int J Biol Macromol. 2019 Aug 15;135:887-897. doi: 10.1016/j.ijbiomac.2019.05.136. Epub 2019 May 25.
5	Differential Proteomic Analysis of Dimethylnitrosamine (DMN)-Induced Liver Fibrosis.Proteomics. 2017 Nov;17(22). doi: 10.1002/pmic.201700267.
6	Emerging Concepts in Brain Glucose Metabolic Functions: From Glucose Sensing to How the Sweet Taste of Glucose Regulates Its Own Metabolism in Astrocytes and Neurons.Neuromolecular Med. 2018 Sep;20(3):281-300. doi: 10.1007/s12017-018-8503-0. Epub 2018 Jul 18.